Summary of study ST000876

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000607. The data can be accessed directly via it's Project DOI: 10.21228/M86Q34 This work is supported by NIH grant, U2C- DK119886.

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Study IDST000876
Study TitleHuman serum for a patient with neuropathy being treated with L-serine.
Study Typedrug dosage
Study SummaryOral serine dosing over 52 week study period
Institute
University of Helsinki
DepartmentMolecular Neurology
Last NameYlikallio
First NameEmil
AddressHartmaninkatu 8, 00290 Helsinki, Finland
Emailemil.ylikallio@helsinki.fi
PhoneNone
Submit Date2017-09-05
PublicationsClinical and metabolic consequences of L-serine supplementation in hereditary sensory and autonomic neuropathy type 1C, Cold Spring Harbor Molecular Case Studies
Analysis Type DetailLC-MS
Release Date2017-10-11
Release Version1
Emil Ylikallio Emil Ylikallio
https://dx.doi.org/10.21228/M86Q34
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Project:

Project ID:PR000607
Project DOI:doi: 10.21228/M86Q34
Project Title:Human serum for a patient with neuropathy being treated with L-serine.
Project Summary:Human serum for a patient with neuropathy being treated with L-serine.
Institute:University of Helsinki
Last Name:Ylikallio
First Name:Emil
Address:Haartmaninkatu 8, 00290, Helsinki, Finland
Email:emil.ylikallio@helsinki.fi
Phone:None

Subject:

Subject ID:SU000903
Subject Type:Human
Subject Species:Homo sapiens
Taxonomy ID:9606
Species Group:Human

Factors:

Subject type: Human; Subject species: Homo sapiens (Factor headings shown in green)

mb_sample_id local_sample_id L-serine (mg/kg/day) time point (weeks)
SA049379week6_100100 6
SA049380week52_200200 52
SA049381week9_200200 9
SA049382week12_300300 12
SA049383weel15_400400 15
SA049384week18_400400 18
SA049385week21_400400 21
SA049386week30_400400 30
SA049387week38_400400 38
SA049388week44_400400 44
SA049389week3_5050 3
SA049377week0_0- -
SA049378week-1_0- -
Showing results 1 to 13 of 13

Collection:

Collection ID:CO000897
Collection Summary:None
Sample Type:Blood
Blood Serum Or Plasma:Serum

Treatment:

Treatment ID:TR000917
Treatment Summary:Oral L-serine
Treatment Compound:L-serine
Treatment Route:Oral
Treatment Dose:0-400 mg/kg/day
Treatment Doseduration:52 weeks

Sample Preparation:

Sampleprep ID:SP000910
Sampleprep Summary:None

Combined analysis:

Analysis ID AN001413
Analysis type MS
Chromatography type None (Direct infusion)
Chromatography system None
Column none
MS Type ESI
MS instrument type Triple quadrupole
MS instrument name Waters Xevo-TQ-S
Ion Mode POSITIVE
Units ┬ÁM

Chromatography:

Chromatography ID:CH000988
Instrument Name:None
Column Name:none
Chromatography Type:None (Direct infusion)

MS:

MS ID:MS001304
Analysis ID:AN001413
Instrument Name:Waters Xevo-TQ-S
Instrument Type:Triple quadrupole
MS Type:ESI
Ion Mode:POSITIVE
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