Summary of study ST001140

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000761. The data can be accessed directly via it's Project DOI: 10.21228/M89Q32 This work is supported by NIH grant, U2C- DK119886.

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Study IDST001140
Study TitleChanges in the Canine Plasma Lipidome after Short- and Long-Term Excess Glucocorticoid Exposure
Study SummaryGlucocorticoids (GCs) are widely used in veterinary and human medicine. Chromic endogenous or iatrogenic GC overexposure impairs metabolic function and can result in diverse side-effects, including Cushing’s syndrome. This study examines the effects of experimentally induced short-term and long-term GC excess (induced by prednisolone and tetracosactide, respectively) on the plasma lipidome of Beale dogs. Both, long- and short-term GC resulted in significant changes of the plasma lipidome.
Institute
National University of Singapore;University of Zurich
DepartmentSingapore Lipidomics Incubator (SLING);Vetsuisse Faculty, University of Zurich
LaboratorySingapore Lipidomics Incubator (SLING), National University of Singapore
Last NameBurla
First NameBo
Address28 Medical Drive, Singapore 117456, Singapore
Emailbo.burla@nus.edu.sg
Phone+6565166683
Submit Date2019-01-19
Num Groups2
Total Subjects14
Num Males9
Num Females5
Raw Data AvailableYes
Raw Data File Type(s).d
Analysis Type DetailLC-MS
Release Date2019-03-06
Release Version1
Bo Burla Bo Burla
https://dx.doi.org/10.21228/M89Q32
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Project:

Project ID:PR000761
Project DOI:doi: 10.21228/M89Q32
Project Title:Changes in the Canine Plasma Lipidome after Short- and Long-Term Excess Glucocorticoid Exposure
Project Summary:Glucocorticoids (GCs) are widely used in veterinary and human medicine. Chromic endogenous or iatrogenic GC overexposure impairs metabolic function and can result in diverse side-effects, including Cushing’s syndrome. This study examines the effects of experimentally induced short-term and long-term GC excess (induced by prednisolone and tetracosactide, respectively) on the plasma lipidome of Beale dogs. Both, long- and short-term GC resulted in significant changes of the plasma lipidome.
Institute:National University of Singapore;University of Zurich
Department:Singapore Lipidomics Incubator (SLING);Vetsuisse Faculty, University of Zurich
Laboratory:Singapore Lipidomics Incubator (SLING)
Last Name:Burla
First Name:Bo
Address:28 Medical Drive, Singapore 117456, Singapore
Email:bo.burla@nus.edu.sg
Phone:+6565166683
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