Summary of study ST001610

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001035. The data can be accessed directly via it's Project DOI: 10.21228/M8X39Q This work is supported by NIH grant, U2C- DK119886.

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Study IDST001610
Study TitleControl (DMSO 0.1%; v/v) and 10 µM DRB18 treated A549 lung cancer cells in vitro for 48 hours
Study TypeAnticancer compound treatment experiment
Study SummaryControl (DMSO 0.1%; v/v) and 10 µM DRB18 were used to treated 5 million A549 lung cancer cells in vitro for 48 hours. The untargeted metabolomics analysis was performed on the cell lysates. The main objective of the study was to determine changes in metabolite abundances in lung cancer after treatment with DRB18, an inhibitor of glucose transporter proteins.
Institute
Ohio University
DepartmentBiological Sciences
LaboratoryDr. Xiaozhuo Chen, Edison biotechnology Institute
Last NameShriwas
First NamePratik
Address172 Water Tower, Building 25, The Ridges, Konnekar Research Centerm Athens Ohio - 45701, USA
Emailps774614@ohio.edu
Phone740-603-3801
Submit Date2020-11-08
Num Groups2
Raw Data AvailableYes
Raw Data File Type(s).raw
Analysis Type DetailLC-MS
Release Date2020-12-09
Release Version1
Pratik Shriwas Pratik Shriwas
https://dx.doi.org/10.21228/M8X39Q
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Project:

Project ID:PR001035
Project DOI:doi: 10.21228/M8X39Q
Project Title:Untargeted metabolomics analysis of A549 cancer cells treated in vitro and in vivo by control (DMSO) or DRB18
Project Type:Untargeted quantitative metabolomics analysis
Project Summary:DR18, a novel anticancer compound was used to A549 lung cancer cells in vitro and A549 cell line derived xenograft tumors in vivo in nude mice. The untargeted metabolomics data was generated from these studies.
Institute:Ohio University
Department:Biological Sciences
Laboratory:Dr. Xiaozhuo Chen, Edison biotechnology Institute
Last Name:Shriwas
First Name:Pratik
Address:172 Water Tower, Building 25, The Ridges, Konnekar Research Centerm Athens Ohio - 45701, USA
Email:ps774614@ohio.edu
Phone:740-603-3801
Contributors:Campus Chemical Instrument Center, Ohio State University
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