Summary of Study ST002392
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001539. The data can be accessed directly via it's Project DOI: 10.21228/M8RT4H This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
Study ID | ST002392 |
Study Title | Candida albicans NMR exometabolome |
Study Summary | The NMR-based metabolomics analysis of 95 C. albicans isolates using the culture supernatants collected after 14h of incubation. The processed data are used as binns or as annotated and quantified metabolites data for study of the isolates variability within and between genomic clades. |
Institute | Bioaster |
Department | Omics Hub |
Laboratory | Metabolomics |
Last Name | Bunescu |
First Name | Andrei |
Address | 40, avenue Tony Garnier, Lyon, 69007 |
andrei.bunescu@bioaster.org | |
Phone | +33481110650 |
Submit Date | 2022-12-06 |
Raw Data Available | Yes |
Raw Data File Type(s) | fid |
Analysis Type Detail | NMR |
Release Date | 2023-06-06 |
Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Project:
Project ID: | PR001539 |
Project DOI: | doi: 10.21228/M8RT4H |
Project Title: | Clade delineation and isolate-specific variability of Candida albicans exometabolome |
Project Summary: | The study includes the NMR-based metabolomics analysis of 95 C. albicans isolates from most of representative genomic clades including the so called clade 13, C. africana. The metabolomics study is based on the supernatants of C. albicans growth after 14h of incubation. All generated data were then quantified with the help of Chenomx NMR suite. |
Institute: | Bioaster |
Department: | Omics Hub |
Laboratory: | Metabolomics |
Last Name: | Bunescu |
First Name: | Andrei |
Address: | 40, avenue Tony Garnier, Lyon, 69007 |
Email: | andrei.bunescu@bioaster.org |
Phone: | +33 (0)4.81.11.06.50 |
Funding Source: | We received funding from the European Union's Horizon 2020 research and innovation program under the Marie Sklodowska-Curie action, Innovative Training Network: FunHoMic; grant N° 812969. BIOASTER received funding from the French Government ‘Investissement d'Avenir’ program (Grant No. ANR-10-AIRT-03). |
Subject:
Subject ID: | SU002481 |
Subject Type: | Yeast |
Subject Species: | Candida albicans |
Species Group: | Yeast |
Factors:
Subject type: Yeast; Subject species: Candida albicans (Factor headings shown in green)
mb_sample_id | local_sample_id | Conditions | Type | Media | Cluster | Country | Site | Provenance | PreCultureMorphology |
---|---|---|---|---|---|---|---|---|---|
SA238197 | YPD B_12 | Mediablank | Blank | YPDbroth | Control | - | - | - | - |
SA238198 | YPD A_09 | Mediablank | Blank | YPDbroth | Control | - | - | - | - |
SA238199 | YPD A_05 | Mediablank | Blank | YPDbroth | Control | - | - | - | - |
SA238200 | YPD A_11 | Mediablank | Blank | YPDbroth | Control | - | - | - | - |
SA238201 | YPD B_10 | Mediablank | Blank | YPDbroth | Control | - | - | - | - |
SA238202 | YPD B_04 | Mediablank | Blank | YPDbroth | Control | - | - | - | - |
SA238203 | YPD A_03 | Mediablank | Blank | YPDbroth | Control | - | - | - | - |
SA238204 | YPD B_06 | Mediablank | Blank | YPDbroth | Control | - | - | - | - |
SA238205 | YPD B_02 | Mediablank | Blank | YPDbroth | Control | - | - | - | - |
SA238206 | YPD A_01 | Mediablank | Blank | YPDbroth | Control | - | - | - | - |
SA238207 | YPD B_08 | Mediablank | Blank | YPDbroth | Control | - | - | - | - |
SA238208 | YPD B_14 | Mediablank | Blank | YPDbroth | Control | - | - | - | - |
SA238209 | YPD A_07 | Mediablank | Blank | YPDbroth | Control | - | - | - | - |
SA238210 | YPD A_13 | Mediablank | Blank | YPDbroth | Control | - | - | - | - |
SA238211 | succinate B_10 | Succinatestandard | Standard | water | Blank | - | - | - | - |
SA238212 | succinate A_03 | Succinatestandard | Standard | water | Blank | - | - | - | - |
SA238213 | succinate B_08 | Succinatestandard | Standard | water | Blank | - | - | - | - |
SA238214 | succinate A_13 | Succinatestandard | Standard | water | Blank | - | - | - | - |
SA238215 | succinate A_09 | Succinatestandard | Standard | water | Blank | - | - | - | - |
SA238216 | succinate B_12 | Succinatestandard | Standard | water | Blank | - | - | - | - |
SA238217 | succinate B_06 | Succinatestandard | Standard | water | Blank | - | - | - | - |
SA238218 | succinate A_07 | Succinatestandard | Standard | water | Blank | - | - | - | - |
SA238219 | succinate B_01 | Succinatestandard | Standard | water | Blank | - | - | - | - |
SA238220 | succinate A_11 | Succinatestandard | Standard | water | Blank | - | - | - | - |
SA238221 | succinate B_14 | Succinatestandard | Standard | water | Blank | - | - | - | - |
SA238222 | succinate A_01 | Succinatestandard | Standard | water | Blank | - | - | - | - |
SA238223 | succinate A_05 | Succinatestandard | Standard | water | Blank | - | - | - | - |
SA238224 | succinate A_04 | Succinatestandard | Standard | water | Blank | - | - | - | - |
SA238225 | CEC3548_03 | Supernatantsample | Sample | YPDbroth | A | Belgium | commensal | Human | no slide |
SA238226 | CEC3548_04 | Supernatantsample | Sample | YPDbroth | A | Belgium | commensal | Human | no slide |
SA238227 | CEC3548_02 | Supernatantsample | Sample | YPDbroth | A | Belgium | commensal | Human | yeast |
SA238228 | CEC3548_01 | Supernatantsample | Sample | YPDbroth | A | Belgium | commensal | Human | yeast |
SA238229 | CEC3548_05 | Supernatantsample | Sample | YPDbroth | A | Belgium | commensal | Human | yeast |
SA238230 | CEC3548_06 | Supernatantsample | Sample | YPDbroth | A | Belgium | commensal | Human | yeast |
SA238231 | CEC3715_04 | Supernatantsample | Sample | YPDbroth | A | France | superficial | Human | no slide |
SA238232 | CEC3715_03 | Supernatantsample | Sample | YPDbroth | A | France | superficial | Human | no slide |
SA238233 | CEC3715_05 | Supernatantsample | Sample | YPDbroth | A | France | superficial | Human | yeast |
SA238234 | CEC3715_02 | Supernatantsample | Sample | YPDbroth | A | France | superficial | Human | yeast |
SA238235 | CEC3715_01 | Supernatantsample | Sample | YPDbroth | A | France | superficial | Human | yeast |
SA238236 | CEC3715_06 | Supernatantsample | Sample | YPDbroth | A | France | superficial | Human | yeast |
SA238237 | CEC4038_03 | Supernatantsample | Sample | YPDbroth | A | UK | superficial | Human | long pseudohyphae |
SA238238 | CEC4038_04 | Supernatantsample | Sample | YPDbroth | A | UK | superficial | Human | long pseudohyphae |
SA238239 | CEC4038_06 | Supernatantsample | Sample | YPDbroth | A | UK | superficial | Human | no slide |
SA238240 | CEC4038_05 | Supernatantsample | Sample | YPDbroth | A | UK | superficial | Human | no slide |
SA238241 | CEC4038_01 | Supernatantsample | Sample | YPDbroth | A | UK | superficial | Human | yeast |
SA238242 | CEC4038_02 | Supernatantsample | Sample | YPDbroth | A | UK | superficial | Human | yeast |
SA238243 | CEC4254_02 | Supernatantsample | Sample | YPDbroth | B | France | invasive | Human | yeast |
SA238244 | CEC4254_01 | Supernatantsample | Sample | YPDbroth | B | France | invasive | Human | yeast |
SA238245 | CEC4254_03 | Supernatantsample | Sample | YPDbroth | B | France | invasive | Human | yeast |
SA238246 | CEC4254_05 | Supernatantsample | Sample | YPDbroth | B | France | invasive | Human | yeast |
SA238247 | CEC4254_04 | Supernatantsample | Sample | YPDbroth | B | France | invasive | Human | yeast |
SA238248 | CEC4254_06 | Supernatantsample | Sample | YPDbroth | B | France | invasive | Human | yeast |
SA238249 | CEC3708_06 | Supernatantsample | Sample | YPDbroth | B | France | superficial | Human | yeast |
SA238250 | CEC3708_02 | Supernatantsample | Sample | YPDbroth | B | France | superficial | Human | yeast |
SA238251 | CEC3708_04 | Supernatantsample | Sample | YPDbroth | B | France | superficial | Human | yeast |
SA238252 | CEC3708_05 | Supernatantsample | Sample | YPDbroth | B | France | superficial | Human | yeast |
SA238253 | CEC3708_01 | Supernatantsample | Sample | YPDbroth | B | France | superficial | Human | yeast |
SA238254 | CEC3708_03 | Supernatantsample | Sample | YPDbroth | B | France | superficial | Human | yeast |
SA238269 | CEC3672_01 | Supernatantsample | Sample | YPDbroth | C01 | France | invasive | Human | few hyphae |
SA238270 | CEC3672_02 | Supernatantsample | Sample | YPDbroth | C01 | France | invasive | Human | few hyphae |
SA238271 | CEC3672_06 | Supernatantsample | Sample | YPDbroth | C01 | France | invasive | Human | no slide |
SA238272 | CEC3672_05 | Supernatantsample | Sample | YPDbroth | C01 | France | invasive | Human | no slide |
SA238273 | CEC3672_03 | Supernatantsample | Sample | YPDbroth | C01 | France | invasive | Human | yeast |
SA238274 | CEC3672_04 | Supernatantsample | Sample | YPDbroth | C01 | France | invasive | Human | yeast |
SA238275 | CEC3678_03 | Supernatantsample | Sample | YPDbroth | C01 | France | superficial | Human | no slide |
SA238276 | CEC4512_03 | Supernatantsample | Sample | YPDbroth | C01 | France | superficial | Human | no slide |
SA238277 | CEC4512_04 | Supernatantsample | Sample | YPDbroth | C01 | France | superficial | Human | no slide |
SA238278 | CEC3678_04 | Supernatantsample | Sample | YPDbroth | C01 | France | superficial | Human | no slide |
SA238279 | CEC4512_06 | Supernatantsample | Sample | YPDbroth | C01 | France | superficial | Human | short pseudohyphae |
SA238280 | CEC4512_05 | Supernatantsample | Sample | YPDbroth | C01 | France | superficial | Human | short pseudohyphae |
SA238281 | CEC4256_05 | Supernatantsample | Sample | YPDbroth | C01 | France | superficial | Human | short pseudohyphae/hyphae |
SA238282 | CEC4256_06 | Supernatantsample | Sample | YPDbroth | C01 | France | superficial | Human | short pseudohyphae/hyphae |
SA238283 | CEC3660_04 | Supernatantsample | Sample | YPDbroth | C01 | France | superficial | Human | with long pseudohyphae |
SA238284 | CEC3660_03 | Supernatantsample | Sample | YPDbroth | C01 | France | superficial | Human | with long pseudohyphae |
SA238285 | CEC3678_06 | Supernatantsample | Sample | YPDbroth | C01 | France | superficial | Human | yeast |
SA238286 | CEC3660_01 | Supernatantsample | Sample | YPDbroth | C01 | France | superficial | Human | yeast |
SA238287 | CEC4512_02 | Supernatantsample | Sample | YPDbroth | C01 | France | superficial | Human | yeast |
SA238288 | CEC3679_04 | Supernatantsample | Sample | YPDbroth | C01 | France | superficial | Human | yeast |
SA238289 | CEC4256_02 | Supernatantsample | Sample | YPDbroth | C01 | France | superficial | Human | yeast |
SA238290 | CEC4256_01 | Supernatantsample | Sample | YPDbroth | C01 | France | superficial | Human | yeast |
SA238291 | CEC3660_02 | Supernatantsample | Sample | YPDbroth | C01 | France | superficial | Human | yeast |
SA238292 | CEC3660_06 | Supernatantsample | Sample | YPDbroth | C01 | France | superficial | Human | yeast |
SA238293 | CEC3660_05 | Supernatantsample | Sample | YPDbroth | C01 | France | superficial | Human | yeast |
SA238294 | CEC3679_01 | Supernatantsample | Sample | YPDbroth | C01 | France | superficial | Human | yeast |
SA238295 | CEC3678_02 | Supernatantsample | Sample | YPDbroth | C01 | France | superficial | Human | yeast |
SA238296 | CEC3678_01 | Supernatantsample | Sample | YPDbroth | C01 | France | superficial | Human | yeast |
SA238297 | CEC3679_02 | Supernatantsample | Sample | YPDbroth | C01 | France | superficial | Human | yeast |
SA238298 | CEC4256_04 | Supernatantsample | Sample | YPDbroth | C01 | France | superficial | Human | yeast |
SA238299 | CEC3679_03 | Supernatantsample | Sample | YPDbroth | C01 | France | superficial | Human | yeast |
SA238300 | CEC4256_03 | Supernatantsample | Sample | YPDbroth | C01 | France | superficial | Human | yeast |
SA238301 | CEC4512_01 | Supernatantsample | Sample | YPDbroth | C01 | France | superficial | Human | yeast |
SA238302 | CEC3679_05 | Supernatantsample | Sample | YPDbroth | C01 | France | superficial | Human | yeast |
SA238303 | CEC3678_05 | Supernatantsample | Sample | YPDbroth | C01 | France | superficial | Human | yeast |
SA238304 | CEC3679_06 | Supernatantsample | Sample | YPDbroth | C01 | France | superficial | Human | yeast |
SA238305 | CEC3534_05 | Supernatantsample | Sample | YPDbroth | C01 | Morocco | commensal | Human | no slide |
SA238306 | CEC3534_06 | Supernatantsample | Sample | YPDbroth | C01 | Morocco | commensal | Human | no slide |
SA238307 | CEC3534_03 | Supernatantsample | Sample | YPDbroth | C01 | Morocco | commensal | Human | yeast |
SA238308 | CEC3534_04 | Supernatantsample | Sample | YPDbroth | C01 | Morocco | commensal | Human | yeast |
SA238309 | CEC3534_01 | Supernatantsample | Sample | YPDbroth | C01 | Morocco | commensal | Human | yeast |
SA238310 | CEC3534_02 | Supernatantsample | Sample | YPDbroth | C01 | Morocco | commensal | Human | yeast |
Collection:
Collection ID: | CO002474 |
Collection Summary: | The 96 clinical C. albicans isolates from the Fungal Biology and Pathogenecity Unit of the Institut Pasteur(Paris, France). |
Sample Type: | Yeast cells |
Storage Conditions: | -80℃ |
Treatment:
Treatment ID: | TR002493 |
Treatment Summary: | No treatement was applied during the yeast culture. The growth of C. albicans isoltes were conducted in YPD media. |
Sample Preparation:
Sampleprep ID: | SP002487 |
Sampleprep Summary: | The C.albicans isolates were grown in deep-weel plates with initial inoculum of 0.2 andin YPD growth media. |
Analysis:
Analysis ID: | AN003897 |
Laboratory Name: | Omics |
Analysis Type: | NMR |
Operator Name: | Andrei Bunescu, ALABAN Leovigildo-Rey |
Data Format: | FID |
Num Factors: | 150 |
Num Metabolites: | 40 |
Units: | µM |
NMR:
NMR ID: | NM000257 |
Analysis ID: | AN003897 |
Instrument Name: | Ascend 600MHz Avance III HD |
Instrument Type: | FT-NMR |
NMR Experiment Type: | 1D-1H |
Spectrometer Frequency: | 600MHz |
NMR Probe: | QCI 1H/13C/15N/31P |
NMR Solvent: | H2O D2O |
NMR Tube Size: | 3mm |
Shimming Method: | topshim and topshim 3d |
Pulse Sequence: | noesygppr1d |
Water Suppression: | presaturation |