Data for ST003606
| Metabolite structure | All data | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 | F10 | F11 | F12 | F13 | F14 | F15 | F16 | F17 | F18 | F19 | F20 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 4-Acetamidobutanoate | 32599.67 | 33131.00 | 27323.33 | 31352.71 | 27530.00 | 29893.33 | 24235.00 | 24952.29 | 21702.33 | 29010.67 | 42821.67 | 46703.67 | 22729.33 | 19743.00 | 34144.00 | 28923.00 | 21612.33 | 81219.67 | 23216.67 | 23172.00 | |
| 5-Hydroxyisourate | 64615.00 | 93548.67 | 25732.67 | 28708.14 | 45556.00 | 48894.00 | 15130.33 | 11007.57 | 27780.67 | 40622.67 | 20987.67 | 54244.00 | 30377.33 | 17129.67 | 19741.67 | 12373.33 | 13613.67 | 8641.67 | 7492.00 | 5687.67 | |
| (5-L-Glutamyl)-L-glutamine | 19836.67 | 30443.33 | 16592.00 | 8957.14 | 15298.67 | 16499.67 | 5009.33 | 6523.50 | 35713.67 | 46694.00 | 16942.67 | 22758.00 | 36980.00 | 35389.00 | 38173.33 | 18196.57 | 31801.67 | 25773.33 | 20842.67 | 8781.43 | |
| 5-Oxoproline | 2450288.00 | 2796434.33 | 1463452.00 | 1580943.29 | 1839452.00 | 1745541.33 | 966575.67 | 829600.71 | 2305815.33 | 2322533.67 | 1990826.33 | 2599866.67 | 1414454.67 | 1336369.67 | 21224198.67 | 1045766.71 | 996306.33 | 895668.67 | 920724.33 | 857853.14 | |
| acetyl-carnitine | 410295.00 | 422384.00 | 179164.67 | 212130.29 | 332707.67 | 232494.00 | 98273.67 | 110884.86 | 420092.00 | 359146.00 | 185800.67 | 438292.67 | 1405671.67 | 770113.67 | 615819.33 | 776578.29 | 610839.00 | 1259914.33 | 174355.33 | 236453.57 | |
| Acetylcholine | 476176.00 | 600001.00 | 231615.00 | 227933.71 | 417040.00 | 465519.33 | 156128.67 | 219040.14 | 724455.33 | 728758.67 | 281317.67 | 426629.67 | 511936.00 | 427352.67 | 624862.00 | 453994.86 | 380271.67 | 549517.00 | 233939.00 | 215716.29 | |
| Adenine | 823170.00 | 704487.33 | 552990.33 | 456291.57 | 787148.00 | 1510874.33 | 981051.33 | 1236815.57 | 856923.33 | 1324817.33 | 1192525.33 | 1305437.00 | 681911.00 | 1097864.67 | 1114093.00 | 1652231.57 | 1061939.67 | 1254597.00 | 1393086.00 | 2125878.00 | |
| Adenosine | 2967158.00 | 2649248.67 | 1911380.33 | 1537554.29 | 1252296.67 | 3152516.67 | 703084.67 | 2201042.71 | 3257434.67 | 5676709.33 | 6185674.67 | 6339034.67 | 712407.00 | 1945005.67 | 2109682.67 | 3433359.43 | 835427.33 | 1047204.33 | 1378059.33 | 2266570.00 | |
| Alanine | 1060921.67 | 1171789.00 | 512173.67 | 626078.14 | 909380.67 | 743331.67 | 477557.00 | 462784.14 | 1039465.00 | 1046292.33 | 584104.33 | 814111.00 | 706389.00 | 588656.00 | 4694113.33 | 508912.00 | 534301.67 | 536376.33 | 344158.00 | 398000.43 | |
| Allantoate | 54406.00 | 79045.67 | 41737.00 | 59398.57 | 112699.00 | 85237.67 | 151930.67 | 89623.43 | 71413.00 | 25479.00 | 22298.00 | 48559.33 | 40746.00 | 28253.33 | 1729199.67 | 43199.00 | 58261.00 | 38341.67 | 38431.33 | 59546.57 | |
| Anthranilate | 58224.00 | 56451.33 | 42165.67 | 40672.86 | 47681.67 | 48980.00 | 42082.33 | 38973.14 | 67798.33 | 66683.33 | 42899.67 | 73124.00 | 75912.67 | 69356.33 | 136496.00 | 51608.86 | 56914.00 | 118694.67 | 77473.67 | 58605.00 | |
| Arginine | 3398100.67 | 3118808.00 | 1298888.67 | 1493022.43 | 2257137.00 | 1774917.67 | 855103.67 | 792692.86 | 2852822.00 | 2947413.00 | 1532225.00 | 1764629.33 | 4884962.33 | 3394904.33 | 25249148.67 | 1599426.43 | 3670190.67 | 2839930.00 | 2808696.00 | 2094743.29 | |
| Asparagine | 207593.00 | 245184.67 | 126658.33 | 190719.00 | 212203.33 | 219644.33 | 98717.00 | 96927.00 | 167709.00 | 157281.33 | 99424.33 | 120430.00 | 135283.67 | 105625.00 | 524469.00 | 116516.43 | 186009.00 | 189812.00 | 103097.67 | 93273.43 | |
| Aspartate | 185885.33 | 225125.33 | 140618.00 | 157733.71 | 132582.67 | 149845.67 | 199724.33 | 148983.71 | 790932.33 | 1539450.00 | 291256.33 | 478218.33 | 213523.00 | 287996.00 | 3059918.00 | 220768.71 | 246686.33 | 271312.00 | 195159.67 | 215675.43 | |
| butanoyl-l-carnitine | 33519.33 | 34943.33 | 31227.33 | 33705.29 | 33659.00 | 34103.67 | 36715.67 | 35169.86 | 36888.33 | 33724.33 | 33357.00 | 33429.67 | 43315.00 | 33933.33 | 74313.67 | 34349.71 | 34795.00 | 39852.67 | 37424.33 | 33380.86 | |
| Cadaverine | 267245.67 | 562463.33 | 212476.33 | 214514.71 | 256861.67 | 357891.67 | 112148.67 | 140514.14 | 9754.00 | - | - | - | 152797.67 | 191617.33 | 141761.33 | 123130.57 | 434344.67 | 349945.00 | 168611.67 | 151764.00 | |
| Creatine | 9111056.67 | 7989728.00 | 4067710.67 | 5399965.43 | 7075470.00 | 6048678.00 | 2510693.00 | 3389695.86 | 9590085.33 | 9803710.33 | 6162312.00 | 8491950.00 | 5478360.00 | 4025804.33 | 3459805.33 | 4796658.14 | 3472283.33 | 3727412.67 | 898509.33 | 2137695.43 | |
| Creatinine | 69887.33 | 73211.33 | 46889.00 | 55188.86 | 65219.00 | 64050.33 | 89992.33 | 47886.71 | 69744.67 | 55576.33 | 44837.00 | 67818.00 | 54781.00 | 53042.67 | 2067242.67 | 125552.57 | 42538.33 | 44479.67 | 17648.00 | 34486.43 | |
| Cys-Gly | 195613.67 | 274737.33 | 75226.33 | 111504.14 | 175791.00 | 165370.67 | 75759.33 | 63474.14 | 200860.67 | 273666.00 | 102946.33 | 163362.00 | 138987.33 | 132382.67 | 70665.00 | 92181.86 | 129256.33 | 125615.33 | 121271.00 | 88908.29 | |
| Cysteine | 1687283.33 | 2080105.00 | 1303936.00 | 1308154.57 | 1358547.67 | 1407811.33 | 789844.33 | 705730.14 | 1011247.33 | 1202831.67 | 931535.00 | 1317171.33 | 1354820.67 | 1119103.00 | 1110077.67 | 944643.57 | 1598317.67 | 1263500.67 | 818222.33 | 726139.43 | |
| gamma-Glutamyl-gamma-aminobutyrate | 122301.33 | 139395.00 | 74343.67 | 51391.71 | 97519.00 | 84464.67 | 45785.00 | 35461.57 | 203813.00 | 218547.33 | 106657.33 | 89892.67 | 240693.33 | 214386.33 | 286834.00 | 100861.57 | 154255.00 | 157544.33 | 146984.33 | 67245.71 | |
| gamma-Glutamyl-Se-methylselenocysteine | 17513.33 | 30037.00 | 15532.67 | 18772.57 | 46073.33 | 33104.00 | 47976.67 | 30420.57 | 31236.33 | 2915.67 | 6957.50 | 9929.67 | 19891.67 | 9838.00 | 875269.50 | 14149.00 | 14765.50 | 28063.50 | 9995.67 | 21567.29 | |
| gamma-L-Glutamyl-D-alanine | 55043.00 | 68795.33 | 43596.00 | 49645.00 | 57961.33 | 42118.67 | 55313.33 | 47846.71 | 119539.67 | 103831.67 | 55890.33 | 56784.00 | 114503.33 | 108378.33 | 189018.67 | 103839.57 | 91851.00 | 82961.33 | 83500.33 | 61084.57 | |
| gamma-L-Glutamyl-L-cysteine | 201275.00 | 287554.67 | 133377.00 | 190348.00 | 185136.67 | 171961.00 | 135694.67 | 126502.86 | 121652.33 | 146062.33 | 82482.00 | 145543.33 | 113680.67 | 95901.67 | 93338.67 | 95706.29 | 201602.67 | 175861.67 | 207313.00 | 140845.00 | |
| gamma-L-Glutamylputrescine | 78917.33 | 84749.33 | 55457.67 | 32807.86 | 55338.00 | 81464.67 | 30988.00 | 26991.14 | 223539.00 | 177362.33 | 110909.33 | 70673.33 | 168800.33 | 184170.33 | 226204.67 | 108306.00 | 120401.67 | 113986.00 | 108534.67 | 55970.00 | |
| Glutamate | 6355857.33 | 7244327.33 | 3656141.00 | 4450462.00 | 5022697.33 | 5069335.33 | 2281090.00 | 2431369.86 | 6518040.00 | 6599375.33 | 5594943.33 | 7064858.67 | 3942592.00 | 3834022.00 | 5139772.33 | 3296003.71 | 2954350.00 | 2747653.33 | 2999677.00 | 2740554.29 | |
| Glutamine | 1322828.33 | 1443203.00 | 804728.00 | 695853.14 | 965277.33 | 901449.67 | 490739.67 | 372320.43 | 937402.33 | 967025.00 | 918260.00 | 1499694.00 | 723636.33 | 532811.00 | 640053.67 | 325478.29 | 363721.67 | 314507.67 | 305009.33 | 283008.00 | |
| Glutathione 13C10 | 4157.35 | 3883.58 | - | - | 7837.67 | 4667.22 | 2118.09 | 3010.95 | - | - | - | - | - | - | 136822.01 | 3648.68 | 170263.80 | 124690.87 | 98486.80 | 44802.42 | |
| g-Oxalo-crotonate | 383604.67 | 413116.00 | 107395.00 | 177440.14 | 456360.00 | 392396.67 | 105975.67 | 125554.29 | 1172273.00 | 957300.33 | 344968.33 | 369926.67 | 311863.67 | 336011.33 | 1110175.00 | 191572.14 | 296877.33 | 348387.67 | 167830.00 | 182862.14 | |
| Guanidinoacetate | 134421.67 | 78519.00 | 63894.67 | 73855.57 | 109414.67 | 62128.33 | 29697.00 | 54721.43 | 235887.00 | 156532.00 | 146510.00 | 181793.67 | 178414.67 | 74369.33 | 168506.67 | 195553.71 | 134320.33 | 56129.33 | 60449.00 | 87095.43 | |
| Histidine | 224972.00 | 329338.67 | 125637.67 | 131266.29 | 216269.33 | 235981.33 | 212494.00 | 117807.71 | 276992.00 | 217055.33 | 127486.67 | 137603.00 | 201188.00 | 200194.33 | 922609.67 | 137932.14 | 226046.67 | 233784.33 | 237380.33 | 167363.00 | |
| Indole-3-acetate | 134113.33 | 186591.33 | 65403.33 | 131204.00 | 235812.33 | 152549.67 | 54204.00 | 91603.00 | 187535.67 | 181622.33 | 180561.33 | 453087.67 | 293267.33 | 186229.33 | 210940.67 | 191210.71 | 144090.67 | 128572.33 | 102880.00 | 119847.43 | |
| Indolepyruvate | 12546.33 | 22392.00 | 6622.67 | 6890.17 | 19882.67 | 17338.67 | 14308.67 | 9112.00 | 26395.67 | 15147.00 | 8660.33 | 10614.33 | 19480.00 | 17340.33 | 403092.67 | 12226.14 | 14688.00 | 28287.33 | 34893.00 | 16836.57 | |
| kynurenine | 21141.00 | 22397.33 | 21292.33 | 13449.86 | 6105.33 | 25543.67 | 7735.33 | 12624.43 | 36760.33 | 28047.67 | 20122.33 | 32724.67 | 7810.00 | 5024.67 | 41534.00 | 25976.00 | 5971.33 | 6924.33 | 5545.67 | 7516.71 | |
| L-Citrulline | 1650525.33 | 1608878.00 | 773156.33 | 786451.14 | 1771460.67 | 1297759.67 | 806856.67 | 867967.86 | 389958.33 | 239514.33 | 233996.00 | 318854.67 | 337428.67 | 174593.33 | 629337.67 | 309553.29 | 284555.67 | 247854.00 | 315059.33 | 335305.14 | |
| Leucine | 1911891.00 | 2403073.00 | 1166847.33 | 966985.29 | 1928032.33 | 1670134.00 | 972753.67 | 914480.14 | 4187096.33 | 3428315.00 | 1942763.67 | 1259395.00 | 2121218.67 | 2810688.67 | 38210665.00 | 1616831.29 | 2113316.67 | 3198185.33 | 1837347.00 | 1156694.57 | |
| L-Homocysteine | 71123.67 | 32904.00 | 78745.33 | 54390.00 | 47796.00 | 96931.33 | 75482.33 | 90741.71 | 72975.33 | 67934.00 | 40853.33 | 101384.00 | 95456.33 | 66431.00 | 85299.00 | 61916.86 | 63130.00 | 41544.33 | 67704.00 | 88000.71 | |
| L-Methionine S-oxide | 68464.00 | 114309.33 | 45227.33 | 43677.00 | 81053.00 | 52586.33 | 38868.67 | 43360.57 | 155871.33 | 107840.00 | 85062.00 | 28608.67 | 47999.67 | 81731.67 | 469834.00 | 57799.57 | 69682.33 | 94442.67 | 81887.33 | 53465.86 | |
| Methionine | 324492.33 | 426065.67 | 205374.00 | 154804.00 | 312934.67 | 337343.33 | 185779.00 | 128236.14 | 1245430.33 | 982496.00 | 439537.67 | 250870.67 | 497314.67 | 666546.00 | 4388279.00 | 329656.71 | 440413.67 | 442884.33 | 494270.00 | 308938.43 | |
| N-Acetyl-L-citrulline | 15315.67 | 17266.33 | 18662.67 | 5608.43 | 11995.33 | 7797.00 | 4356.33 | 4740.50 | 63890.00 | 42105.67 | 34831.33 | 17761.33 | 48343.00 | 51311.67 | 67511.33 | 46864.71 | 31925.00 | 28227.33 | 31809.00 | 26152.29 | |
| N-Acetylornithine | 90064.67 | 103011.00 | 68932.33 | 35369.14 | 67850.33 | 73538.33 | 45506.67 | 36472.57 | 312107.67 | 242535.00 | 160852.33 | 81458.67 | 233504.00 | 234953.67 | 2356520.00 | 123079.14 | 156860.33 | 158887.33 | 146044.33 | 63016.43 | |
| NAD+ | 69032.00 | 68084.00 | 22700.00 | 18505.57 | 90487.67 | 56429.67 | 80165.00 | 35046.71 | 98099.33 | 159631.00 | 90641.33 | 139329.67 | 175232.33 | 82816.00 | 63376.67 | 88084.29 | 271058.67 | 190113.00 | 403912.00 | 253542.14 | |
| N-formyl kynurenine | 27216.67 | 27809.67 | 33839.67 | 15797.71 | 16684.67 | 19034.33 | 24624.00 | 13275.50 | 55816.67 | 59372.67 | 39349.67 | 31416.33 | 55535.00 | 62903.33 | 77475.33 | 37592.57 | 49747.00 | 34035.33 | 36819.00 | 14391.86 | |
| Nicotinamide | 8421215.33 | 12108483.33 | 4346243.00 | 3419871.29 | 8746607.33 | 11114476.33 | 4853451.00 | 2997287.71 | 10520052.00 | 12374350.00 | 5431551.33 | 5894761.33 | 7164120.67 | 7434267.00 | 4383778.33 | 3507787.71 | 6811772.67 | 9390207.33 | 4689483.00 | 4327373.57 | |
| Ornithine | 119511.00 | 163685.00 | 92796.67 | 113957.43 | 243146.67 | 175150.00 | 301017.33 | 148176.71 | 146367.00 | 61143.00 | 47910.67 | 89833.00 | 92520.00 | 66777.33 | 5972625.33 | 90775.00 | 102768.67 | 116676.00 | 60576.00 | 128662.57 | |
| Phenylalanine | 218092.67 | 349024.00 | 108986.67 | 131172.14 | 240265.67 | 243618.00 | 183457.00 | 116769.29 | 696900.67 | 461360.00 | 211687.67 | 181889.33 | 322358.67 | 344699.00 | 14149649.00 | 228757.29 | 287974.33 | 452150.67 | 285181.00 | 173812.43 | |
| Picolinic acid | 151183.67 | 156449.00 | 136593.67 | 136190.57 | 214483.67 | 209058.67 | 372300.67 | 233514.00 | 115838.33 | 121433.33 | 104760.67 | 108754.00 | 172307.67 | 132183.33 | 162824.33 | 187368.14 | 403476.00 | 476045.33 | 705084.67 | 557602.71 | |
| Proline | 2998283.33 | 3430263.33 | 1208998.67 | 1643286.86 | 3186517.67 | 2601143.33 | 2563332.33 | 1784820.86 | 2437270.33 | 1968282.00 | 1018189.00 | 1689097.00 | 2359078.67 | 1858556.33 | 23967003.67 | 1669700.00 | 2449601.33 | 2685331.00 | 17252896.67 | 12404214.43 | |
| propionyl-carnitine | 75627.67 | 142566.00 | 49363.67 | 28895.14 | 72637.00 | 95036.00 | 39554.33 | 25255.00 | 227830.67 | 290373.00 | 91592.00 | 150878.00 | 327068.67 | 383755.67 | 172639.33 | 167660.43 | 308510.67 | 251816.00 | 63541.00 | 60244.00 | |
| Putrescine | 261452.67 | 545192.67 | 193657.00 | 362852.86 | 917968.67 | 1042741.33 | 868071.67 | 671588.86 | 139112.67 | 151393.00 | 125302.33 | 158856.33 | 241407.00 | 266252.33 | 388871.00 | 603000.57 | 1157218.33 | 1064603.33 | 898383.67 | 809052.71 | |
| S-Adenosyl-L-methionine | 63107.00 | 80475.67 | 35132.33 | 44666.00 | 52617.00 | 57556.00 | 59264.33 | 25559.43 | 32175.67 | 46528.33 | 60560.67 | 86609.33 | 27458.67 | 24324.00 | 31451.33 | 44228.43 | 43911.00 | 28615.33 | 72894.67 | 54270.71 | |
| Serine | 191423.00 | 222980.33 | 135424.00 | 118281.00 | 156377.00 | 172324.00 | 196924.67 | 100545.43 | 253471.00 | 174437.67 | 114404.67 | 131065.00 | 130461.33 | 110903.67 | 7103914.33 | 93233.57 | 113236.67 | 138042.33 | 97048.00 | 84779.71 | |
| Spermidine | 6367838.33 | 9478007.00 | 7488688.67 | 8190239.14 | 3284952.67 | 5976179.67 | 2736743.00 | 3023120.29 | 10384166.33 | 9246599.33 | 11485306.67 | 11860973.33 | 537462.00 | 1576537.67 | 4987323.67 | 6399604.71 | 601159.33 | 629412.67 | 1796949.33 | 2033649.43 | |
| spermidine 13C7 | 441427.17 | 675798.93 | 1257379.33 | 683405.84 | 106387.59 | 173746.50 | 25000.41 | 102259.84 | 3167.93 | 4243.30 | - | - | 56168.39 | 191664.22 | 694192.47 | 559007.59 | 63826.08 | 56480.32 | 64381.89 | 157730.97 | |
| Spermine | 44410.33 | 22938.33 | 115687.33 | 115820.71 | 5934.00 | 11254.33 | 9544.67 | 21501.57 | 109244.00 | 69405.67 | 1569685.33 | 390856.00 | 6285.67 | 5990.00 | 45883.67 | 99100.43 | 3395.67 | 2580.33 | 8003.33 | 12786.29 | |
| Threonine | 183884.67 | 240380.67 | 132682.00 | 111260.71 | 178214.67 | 184827.67 | 148073.67 | 90049.43 | 247611.33 | 185886.67 | 111379.67 | 119528.33 | 140688.67 | 125961.00 | 5104471.33 | 100982.29 | 135373.33 | 149643.67 | 159863.67 | 101796.00 | |
| Tryptophan | 447418.00 | 598034.33 | 232206.00 | 224121.57 | 515779.00 | 494935.00 | 399963.67 | 220308.57 | 500137.67 | 373103.00 | 167170.00 | 256093.00 | 496927.33 | 368666.33 | 1837381.67 | 250345.71 | 445023.00 | 579074.00 | 380018.00 | 267898.86 | |
| Tyrosine | 319990.67 | 447884.67 | 213045.67 | 172814.71 | 324735.33 | 347605.00 | 313104.67 | 198135.00 | 528554.00 | 401765.67 | 204346.33 | 239803.67 | 349170.00 | 368653.67 | 14384324.33 | 231360.71 | 376117.67 | 621061.67 | 604444.67 | 376510.43 | |
| Valine | 3181169.00 | 3497613.00 | 2150965.00 | 2037060.00 | 2713526.00 | 2867858.67 | 2280022.00 | 2016120.86 | 3358633.33 | 2991538.00 | 2133244.00 | 2222116.67 | 2526435.00 | 2592509.67 | 37852021.33 | 2294983.29 | 2550860.00 | 3946212.00 | 3771363.00 | 2832809.86 | |
| Xanthine | 302791.00 | 340301.33 | 242085.67 | 231560.57 | 284271.67 | 304925.33 | 231641.00 | 153351.29 | 315965.67 | 308155.67 | 243569.00 | 234185.00 | 229609.33 | 243291.00 | 5860525.67 | 181347.71 | 279126.00 | 275261.33 | 242490.67 | 196606.57 |
Factors:
| F1 | time (h):18 | E coli treatment:dead | genotype:Cre |
| F2 | time (h):18 | E coli treatment:dead | genotype:Cre KRAS +/+ |
| F3 | time (h):18 | E coli treatment:dead | genotype:HRAS +/+ |
| F4 | time (h):18 | E coli treatment:dead | genotype:WT |
| F5 | time (h):18 | E coli treatment:live | genotype:Cre |
| F6 | time (h):18 | E coli treatment:live | genotype:Cre KRAS +/+ |
| F7 | time (h):18 | E coli treatment:live | genotype:HRAS +/+ |
| F8 | time (h):18 | E coli treatment:live | genotype:WT |
| F9 | time (h):18 | E coli treatment:none | genotype:Cre |
| F10 | time (h):18 | E coli treatment:none | genotype:Cre KRAS +/+ |
| F11 | time (h):18 | E coli treatment:none | genotype:HRAS +/+ |
| F12 | time (h):18 | E coli treatment:none | genotype:WT |
| F13 | time (h):6 | E coli treatment:dead | genotype:Cre |
| F14 | time (h):6 | E coli treatment:dead | genotype:Cre KRAS +/+ |
| F15 | time (h):6 | E coli treatment:dead | genotype:HRAS +/+ |
| F16 | time (h):6 | E coli treatment:dead | genotype:WT |
| F17 | time (h):6 | E coli treatment:live | genotype:Cre |
| F18 | time (h):6 | E coli treatment:live | genotype:Cre KRAS +/+ |
| F19 | time (h):6 | E coli treatment:live | genotype:HRAS +/+ |
| F20 | time (h):6 | E coli treatment:live | genotype:WT |