Data for ST002237
| Metabolite structure | All data | F1 | F2 | F3 | F4 |
|---|---|---|---|---|---|
| 1,3-bisphospho-D-glycerate | - | - | - | - | |
| 1-methylnicotinamide+ | 14721125.30 | 18433498.50 | 9032000.70 | 13088199.30 | |
| 2,3-bisphospho-D-glycerate | 309838.75 | 117026.00 | 419383.56 | 318621.67 | |
| 2/3-phosphoglycerate | 18586364.50 | 11371758.20 | 14663598.80 | 17923852.40 | |
| 2-aminobutanoate | 2226150.40 | 12042786.40 | 2702580.90 | 8247377.90 | |
| 2-aminoisobutanoate | 467377.60 | 430114.60 | 598821.80 | 400987.30 | |
| 2-(Formamido)-N1-(5-phospho-D-ribosyl)acetamidine | 178754.75 | 130991.80 | 304417.60 | 251917.10 | |
| 2-HG | 55464905.30 | 72402320.20 | 42252919.30 | 48674852.10 | |
| 2-hydroxybutanoic acid | 3760301.20 | 61732937.90 | 3623356.60 | 26831471.70 | |
| 2-keto-isovaleric acid | 1152168.11 | 1259475.10 | 1470732.33 | 1063329.00 | |
| 2-ketovaleric acid | 4532742.22 | 4750964.71 | 3183820.00 | 3169455.50 | |
| 2-oxobutanoic acid | 4666176.00 | 4698611.60 | 4032660.30 | 5883374.50 | |
| 3,4-dihydroxymandelic acid | - | - | - | - | |
| 3,4-dihydroxyphenylpropanoate | 23485.67 | 24882.50 | 20545.00 | 20433.00 | |
| 3- / 7-methylguanine | 302180.40 | 429027.50 | 303780.60 | 321121.20 | |
| 3-aminoisobutanoate | 989406.60 | 3724717.00 | 1615078.20 | 1730606.40 | |
| 3-hydroxybutanoic acid | 24076007.70 | 123223805.70 | 19934435.00 | 95881915.10 | |
| 3-hydroxyphenylacetic acid / vanillin | 2551523.10 | 3513273.80 | 3152669.90 | 2706150.40 | |
| 3-hydroxypropanoic acid | 327256884.80 | 242982510.70 | 298849214.10 | 286227365.30 | |
| 3-methoxytyramine | 46187.70 | 80243.60 | 172511.80 | 117579.40 | |
| 3-phosphohydroxypyruvic acid | - | - | - | - | |
| 3-phospho-serine | 155953.60 | 141778.50 | 186741.40 | 161628.20 | |
| 3-ureidopropionic acid | 19470.33 | 29660.50 | 20985.50 | 45463.38 | |
| 4-hydroxybutanoic acid | 4258594.40 | 11310506.00 | 4434953.80 | 8131873.30 | |
| 4-hydroxyphenylacetic acid | 249210.43 | 816429.25 | 357399.12 | 285684.75 | |
| 4-hydroxyphenylpyruvic acid - | 60999.00 | - | 115480.00 | 72297.50 | |
| 4-hydroxyproline | 6267391.60 | 5049922.90 | 4782611.10 | 5232429.50 | |
| 4-phosphopantothenate | - | - | - | - | |
| 5,6-dihydroxyindole | 13689.00 | 18055.50 | 15518.00 | 48638.00 | |
| 5-aminolevulinate | 355276.00 | 368700.00 | 399310.10 | 379597.80 | |
| 5-methylcytosine | 576069.80 | 396507.40 | 500697.40 | 441086.90 | |
| 5-methyl-THF | 23348.00 | 30183.60 | 19009.40 | 31773.33 | |
| 5^-methylthioadenosine | 23530299.20 | 23667206.00 | 21789597.40 | 22226264.70 | |
| 6-aminocaproic acid | 76844426.33 | 74770044.33 | 50565307.00 | 36583849.00 | |
| 6-O-methylguanine | - | - | - | - | |
| 6-phosphogluconic acid | 900363.40 | 440711.80 | 806120.60 | 690017.90 | |
| 6-phosphoglucono-D-lactone | 48082.75 | 71089.25 | 66368.20 | 67814.17 | |
| acetoacetic acid | 3002776.38 | 2856988.00 | 4080212.20 | 2327447.17 | |
| acetylcholine+ | 211585042.50 | 204926424.40 | 193041328.70 | 188538873.50 | |
| aconitic acid | 1043628.22 | 1162526.80 | 11142254.40 | 1889826.30 | |
| adenine | 76837208.50 | 83558624.90 | 76654551.60 | 70728267.80 | |
| adenosine | 575171801.80 | 626745465.90 | 467290322.00 | 482631312.40 | |
| adenylosuccinate | 5101578.60 | 4904434.50 | 4793613.00 | 5156612.30 | |
| ADP | 95906759.80 | 83413498.10 | 83514500.10 | 92516508.10 | |
| ADP-D-glucose | - | - | 31785.50 | 42260.00 | |
| agmatine | 14908.50 | 13231.50 | 15732.00 | 20319.67 | |
| AICA ribonucleotide | 116529.50 | 103062.00 | 54356.44 | 45842.83 | |
| a-KG | 22279406.50 | 17690302.80 | 21700767.30 | 15048736.50 | |
| alanine | 641794706.00 | 635409651.80 | 579421716.40 | 578517265.60 | |
| allantoin | 9155150.90 | 11537508.20 | 7345854.10 | 10498287.20 | |
| AMP / dGMP | 890120555.00 | 920192860.50 | 766668951.70 | 898612898.60 | |
| anandamide | 79140.67 | 192802.60 | 342408.00 | 143767.29 | |
| arginine | 250755067.00 | 187209808.80 | 298778533.00 | 259526919.90 | |
| asparagine | 14089273.90 | 11802050.30 | 18427336.90 | 15794274.00 | |
| aspartic acid | 1638835653.90 | 1686478024.80 | 1548501206.20 | 1623965917.00 | |
| ATP / dGTP | 8925366.60 | 8154952.70 | 8194109.20 | 8242938.30 | |
| b-alanine | 18999999.60 | 19632741.70 | 17066413.20 | 14860089.60 | |
| betaine | 400810577.50 | 388136726.10 | 193472702.70 | 217461382.20 | |
| carbamoyl phosphate | 121347.00 | 107852.25 | 111108.00 | 102814.00 | |
| carnitine+ | 863201260.30 | 813092769.30 | 805078683.70 | 788376432.10 | |
| CDP | 700242.60 | 564391.50 | 568291.40 | 653620.00 | |
| CDP-choline | 22208716.50 | 21814477.30 | 19630481.60 | 20149008.30 | |
| choline+ | 729025521.70 | 685326565.80 | 885117517.60 | 667112913.30 | |
| citraconic acid | 7473690.30 | 6395369.40 | 4456314.00 | 6730085.80 | |
| citramalic acid | 689954.67 | 687667.50 | 1038574.25 | 951903.17 | |
| citrate / citrate(iso) | 970973890.60 | 965393132.70 | 936115728.00 | 785157806.20 | |
| citrulline | 14720361.50 | 10997927.70 | 13381942.30 | 8237180.30 | |
| CMP | 18904266.00 | 20569815.70 | 16314711.30 | 19144130.30 | |
| creatine | 11216936866.70 | 11411210447.10 | 10357372281.00 | 10797109812.80 | |
| Creatinine | 63818491.50 | 71487879.60 | 62941280.60 | 71072336.10 | |
| CTP | 18534.17 | 15806.33 | 18918.20 | 16067.50 | |
| cystathionine | 3856410.50 | 3454104.10 | 3151996.00 | 4392435.00 | |
| cysteine | 71649.56 | 94650.25 | 218969.67 | 205307.62 | |
| cysteine-S-sulfate | - | - | - | - | |
| cystine | - | - | 1224807.00 | - | |
| cytidine | 23935309.90 | 30045311.20 | 19837046.70 | 21106681.20 | |
| cytosine | 871196.70 | 1132244.40 | 966691.60 | 1280860.20 | |
| dADP | 28407.00 | 15864.17 | 15431.00 | 16401.25 | |
| dAMP | 240393.62 | 249505.75 | 376801.67 | 232314.89 | |
| D-arabinono-1,4-lactone | 103441466.10 | 101538196.10 | 88805008.50 | 96348301.40 | |
| dATP | - | 24197.00 | - | - | |
| dCDP | 22270.00 | 12110.00 | - | - | |
| dCMP | 61530.80 | 63312.10 | 34121.40 | 54361.22 | |
| dCTP | 12745.00 | 15727.00 | - | - | |
| dehydroascorbic acid | 48440452.40 | 47290750.50 | 44328735.40 | 61849813.20 | |
| deoxyguanosine | 4943797.00 | 3463868.83 | 6620257.67 | 2619933.50 | |
| deoxyinosine | - | 19624.33 | 90315.00 | - | |
| deoxyuridine | 830613.40 | 1893788.70 | 876564.10 | 1158467.20 | |
| D-erythrose-4-phosphate | 35501.50 | 27813.50 | 28001.25 | 25635.00 | |
| D-galactonic acid | 12686762.90 | 13024463.30 | 9304324.10 | 9166522.30 | |
| D-galactosamine/glucosamine-1-phosphate | 101766.50 | 33779.71 | 96727.70 | 59848.70 | |
| D-galactosamine/glucosamine-6-phosphate | 1034603.70 | 431973.90 | 764806.60 | 662185.10 | |
| dGDP | 206266.00 | - | 579380.00 | 1140809.00 | |
| D-gluconic acid - | 369724.40 | 597526.75 | 278853.00 | 307534.00 | |
| dihydroorotate | 36216.00 | 30827.00 | 37306.50 | - | |
| dimethylglycine | 51151665.90 | 49843092.00 | 57179586.50 | 45377919.80 | |
| DL-DOPA | 21076.50 | 23049.67 | 43822.00 | 35548.00 | |
| DOPAC | 79276.50 | 48522.17 | 68290.33 | 48680.80 | |
| DOPAL | 505457.30 | 711178.70 | 550543.80 | 646632.40 | |
| dopamine / octopamine | 157514.22 | 182683.44 | 337799.80 | 201534.56 | |
| dopamine quinone | 680065.33 | 777098.60 | 642231.00 | 769867.20 | |
| DOPEG | 38920.50 | 32550.00 | - | 32241.50 | |
| DOPET | 44492.67 | 37801.00 | 42920.50 | 32998.00 | |
| D-ribose-1/5-phosphate / D-ribulose 5-phosphate | 16369955.80 | 16812627.20 | 16812830.90 | 14761732.20 | |
| D-sedoheptulose-7-phosphate | 2737761.70 | 2569246.70 | 2538113.70 | 2363312.00 | |
| dTMP | - | - | - | - | |
| dTTP | - | - | - | - | |
| dUMP | 47015.40 | 51838.25 | 60906.00 | - | |
| dUTP | - | - | - | - | |
| epinephrine | 52325.33 | 37850.20 | 82997.90 | 65045.60 | |
| F-1,6/2,6-DP | 6023497.40 | 4383028.70 | 5951731.90 | 6554962.10 | |
| F1P | 526870.00 | 334411.90 | 693895.20 | 521821.30 | |
| F6P / G1P | 11401415.40 | 6010667.80 | 9429491.70 | 9326334.50 | |
| FAD | 125818.00 | 156020.00 | 139207.00 | - | |
| FMN | 52218.00 | 34899.00 | 24351.00 | 37303.00 | |
| folic acid | - | - | - | - | |
| fructose / mannose | 5112179.00 | 2209981.80 | 5118863.90 | 3397488.10 | |
| fumaric acid | 16507348.70 | 19844179.90 | 11843986.60 | 12978139.90 | |
| G6P | 49591575.40 | 49485463.50 | 40149469.40 | 52125412.60 | |
| GABA | 547160689.00 | 509882469.40 | 601412920.30 | 485545267.40 | |
| galactosamine / glucosamine | 308030.30 | 74460.44 | 189739.44 | 75292.90 | |
| galactose / glucose | - | 12724.00 | - | - | |
| GalNAC/GlcNAC/ManNAC | 916913.40 | 888549.00 | 759097.00 | 542968.10 | |
| GAP / DHAP | 7322131.80 | 3779674.80 | 6047435.40 | 7407254.20 | |
| GDP | 8749272.00 | 8784887.90 | 8181978.50 | 9243128.20 | |
| GDP-L-fucose | 380439.90 | 388743.60 | 369321.70 | 397468.00 | |
| glucono-lactone | - | - | - | 2014001.00 | |
| glutamine | 785601614.50 | 532436486.00 | 1222612234.00 | 1096692225.70 | |
| glutaminic acid | 2505151685.60 | 2431121658.00 | 2639410848.10 | 2671878821.50 | |
| glutathione | 69764684.10 | 72490206.10 | 81743599.90 | 91326812.60 | |
| glutathione disulfide | 184491899.90 | 176392919.80 | 151861817.50 | 167122557.30 | |
| glyceraldehyde | - | - | - | - | |
| glyceric acid | 19601497.60 | 20785256.30 | 19047674.20 | 20626073.10 | |
| glycerol 2/3-phosphate | 251383318.50 | 220941860.30 | 193357868.80 | 163555497.90 | |
| glycine | 42542862.90 | 57954093.60 | 35027425.80 | 40654707.40 | |
| glycylglycine | - | 167581.00 | 212577.00 | - | |
| GMP | 115800150.30 | 121511667.60 | 108688761.30 | 113867331.30 | |
| GTP | 319272.10 | 385865.10 | 330562.80 | 402048.30 | |
| guanidine | 5348440.90 | 3890374.00 | 1887956.00 | 3251854.90 | |
| guanidinoacetate | 2773885.60 | 2706024.00 | 1618674.00 | 1873211.70 | |
| guanine | 2443277.90 | 2686073.20 | 3130113.20 | 2090230.30 | |
| guanosine | 10229888.70 | 11391608.70 | 13237069.20 | 8546523.00 | |
| gulonic-lactone | 2496770.75 | 2299900.88 | 2272910.14 | 2075792.29 | |
| histamine | 2064273.40 | 2199540.80 | 1877454.60 | 3971354.90 | |
| histidine | 183833621.30 | 141539152.70 | 228621373.50 | 202127611.80 | |
| homocysteine | 59852.80 | 56476.75 | 87590.86 | 71686.50 | |
| homoserine / theronine | 40896968.30 | 45826925.00 | 57277661.00 | 73951527.60 | |
| homovanillic acid | 43782.40 | 56113.25 | 74412.17 | 99286.25 | |
| hydroxyphenyllactic acid | 2657884.70 | 1298358.50 | 2734412.30 | 1610655.80 | |
| hypoxanthine | 37004470.80 | 40403109.70 | 87191032.90 | 38683722.70 | |
| IDA | 448320.75 | 621619.67 | 495229.71 | 487663.89 | |
| IDP | 54638.00 | - | 36676.00 | 35887.00 | |
| imidazole-4-acetate | 452816.10 | 346738.00 | 367440.10 | 312562.90 | |
| IMP | 77067340.00 | 92151516.20 | 81838795.00 | 92130397.50 | |
| inosine | 38175241.60 | 41821236.20 | 96439410.70 | 39648000.30 | |
| isonictinic acid | 65617.50 | 101571.90 | 119576.20 | 91571.10 | |
| itaconic acid | 76276833.70 | 71997106.00 | 66858769.70 | 73873695.80 | |
| kynurenine | 122085.90 | 279059.40 | 219365.50 | 377737.80 | |
| lactic acid | 7076685290.50 | 4877484305.20 | 6214668270.50 | 5761019207.60 | |
| L-arginino-succinate | 1714145.10 | 1338093.80 | 2355498.70 | 1726727.60 | |
| L-cysteic acid | 440629.00 | - | 368603.50 | - | |
| leucine / leucine(iso) | 163254473.90 | 209325081.40 | 230113686.70 | 257703316.70 | |
| levulinic acid | 2048390.00 | 5927181.00 | 6116447.33 | 6100700.33 | |
| L-NMMA | 1622564.80 | 874325.20 | 1891960.70 | 1073171.30 | |
| lysine | 124395940.50 | 95923042.50 | 124487790.90 | 103655826.00 | |
| maleic acid | 112933576.10 | 107209891.50 | 97778348.60 | 101260171.40 | |
| malic acid | 2839662810.70 | 2754347568.90 | 2467997879.80 | 2558265054.70 | |
| mesaconic acid | 10228000.40 | 9909215.20 | 8034971.20 | 8425956.40 | |
| methionine | 71157245.10 | 28964277.50 | 81923521.90 | 45670284.80 | |
| methyl acetoacetate | - | - | - | - | |
| methylglyoxal | - | 2949878.00 | 2977525.67 | 2689257.50 | |
| methylmalonic acid | 5233968.71 | 8537852.33 | 6762110.89 | 6366013.22 | |
| mevalonic acid | 1385455.00 | 867422.20 | 2282314.33 | 1323706.00 | |
| N1/N8-acetylspermidine | 22801565.20 | 17639644.20 | 19089343.10 | 15638988.40 | |
| N-acetylaspartic acid | 4496373675.60 | 4805689005.40 | 4475351607.10 | 4647748879.50 | |
| N-acetylaspartylglutamic acid | 68803029.90 | 69991175.80 | 58563824.10 | 72871911.50 | |
| N-acetyl-b-alanine | 878822.10 | 587840.30 | 1042019.90 | 858273.60 | |
| N-acetyl-DL-alanine | 4842951.20 | 4964097.10 | 4227126.20 | 3680779.40 | |
| N-acetyl-dopamine | 3620139.60 | 3445180.10 | 2577015.70 | 2254943.50 | |
| N-acetylglucosamine 1/6-phosphate | 35414.33 | 30703.00 | 32448.50 | 31738.00 | |
| N-acetyl-L-glutamic acid | 888628.20 | 831691.10 | 711773.90 | 484122.40 | |
| NAD+ | 126818795.00 | 124747655.80 | 101524553.30 | 111578652.00 | |
| NADH | 511831.86 | 527518.75 | 411157.17 | 477934.57 | |
| NADP+ | 1023375.10 | 962461.30 | 860866.10 | 1082607.40 | |
| NADPH | 136855.90 | 139696.70 | 159353.33 | 164037.50 | |
| N-carbamoyl-L-aspartate | 195892.30 | 139756.78 | 87216.10 | 78762.60 | |
| nicotinamide | 184794223.70 | 179790995.10 | 262118330.80 | 190437074.70 | |
| nicotinamide riboside+ | 1548967.10 | 1711165.10 | 1076885.30 | 1016993.20 | |
| nicotinic acid | 116902.33 | 105153.60 | 145845.80 | 133252.70 | |
| N-methyltryptamine | - | - | - | 14578.00 | |
| NMN | 661013.10 | 648419.20 | 441259.00 | 469232.50 | |
| N,N-dimethylaniline | 545163.30 | 495819.33 | 660942.33 | 482313.56 | |
| norepinephrine | 100977.00 | 101945.70 | 132094.80 | 123158.40 | |
| octopamine | 348458.44 | 250697.38 | 300254.00 | 319322.78 | |
| ornithine | 4188487.00 | 4484841.40 | 3454433.70 | 3217435.80 | |
| orotic acid | 494006.10 | 663666.50 | 550778.90 | 532112.40 | |
| orotidylic acid | - | 31376.00 | 29653.00 | 30664.50 | |
| oxalacetic acid | - | - | 57885.00 | 28630.00 | |
| pantothenic acid | 21414655.20 | 31043474.10 | 23822402.50 | 41530333.10 | |
| phenethylamine | 512145.70 | 438150.50 | 472029.89 | 480753.10 | |
| phenylalanine | 73996568.80 | 59434871.90 | 104996334.90 | 92612107.10 | |
| phenylephrine / synephrine | 82746.78 | 98684.40 | 64042.56 | 58445.30 | |
| phosphocreatine | 69805344.10 | 74108249.30 | 60707784.10 | 51363723.50 | |
| phosphoenolpyruvate | 2314937.20 | 979165.50 | 2696231.60 | 2246721.70 | |
| phosphorylcholine+ | 443162426.90 | 354330996.20 | 367451386.80 | 326623001.50 | |
| picolinic acid | 1980314.60 | 1071474.10 | 945048.10 | 1262853.70 | |
| proline | 267223847.90 | 275163578.70 | 232322025.90 | 246094133.20 | |
| PRPP | 23497.00 | - | - | 25624.50 | |
| pseudouridine | 3263331.90 | 4109207.30 | 2944494.30 | 3097706.70 | |
| putrescine | 5576899.30 | 5165200.50 | 5560861.70 | 4558147.30 | |
| pyridoxine | 37559.75 | 31853.56 | 33104.50 | 30325.56 | |
| pyruvic acid | 23510615.90 | 16366913.00 | 18382576.60 | 18106615.20 | |
| (S)-4-hydroxymandelonitrile + | - | 319156.00 | 724268.00 | 849101.00 | |
| S-adenosyl-L-homocysteine | 478447.10 | 411283.20 | 480486.70 | 517444.56 | |
| S-adenosyl-L-methionine+ | 22833618.30 | 24348778.10 | 18770713.80 | 21510529.70 | |
| S-adenosylmethioninamine+ | 30824.00 | - | - | - | |
| serine | 81627629.70 | 69543681.80 | 85928664.50 | 93229587.70 | |
| serotonin | 2978817.80 | 3114301.60 | 2995730.30 | 3837123.90 | |
| spermidine | 41965750.00 | 41728157.00 | 38031347.50 | 41345877.50 | |
| spermine | 24877328.30 | 24385696.20 | 23841086.60 | 24231222.50 | |
| succinic acid | 133088286.30 | 126115128.50 | 102078327.10 | 109788953.20 | |
| succinic semialdehyde | - | - | - | - | |
| taurine | 3936293126.00 | 3882242893.30 | 3201391762.90 | 3467316411.60 | |
| thiamine+ | 3966608.10 | 3049499.00 | 4803780.10 | 3711914.10 | |
| thymidine | 749087.00 | 1815564.70 | 925143.30 | 1112622.20 | |
| thymine | 1313647.90 | 2224403.60 | 1734364.40 | 1688796.30 | |
| tryptamine | - | 28465.50 | 37193.67 | 14790.00 | |
| tryptophan | 15525506.00 | 14788978.90 | 20144619.70 | 18458802.20 | |
| tyramine | 67309.50 | 71188.80 | 67377.60 | 68914.20 | |
| tyrosine | 39878434.90 | 16160970.60 | 45854575.20 | 26488436.30 | |
| UDP | 4089742.00 | 3615149.70 | 3626824.00 | 4482833.60 | |
| UDP-D-glucose | 16421271.70 | 16754222.50 | 14338023.80 | 15581840.50 | |
| UDP-N-acetyl-galactosamine/UDP-N-acetyl-glucosamine | 17528294.80 | 18788064.40 | 15291013.00 | 17305236.90 | |
| UMP | 41922598.60 | 48272443.40 | 35527898.40 | 47790732.40 | |
| uracil | 59807930.00 | 86537401.80 | 73274994.10 | 57825308.40 | |
| urea | 39998683.50 | 55703992.30 | 35871205.90 | 44361587.70 | |
| uric acid | 2658477.10 | 3347729.40 | 2556592.00 | 3183752.60 | |
| uridine | 38318838.90 | 45992417.00 | 33723517.30 | 35175451.90 | |
| UTP | 64018.43 | 98906.86 | 91392.00 | 109025.50 | |
| valine | 63462918.90 | 82147166.40 | 79403137.10 | 90323822.50 | |
| xanthine | 10763641.00 | 12623191.20 | 21805759.30 | 12069272.70 | |
| xanthosine | - | - | - | - | |
| XMP | 26835.50 | 24417.25 | 102613.29 | 26592.00 | |
| y-glutamylcysteine | 195708.00 | 130995.00 | 116430.00 | 222456.50 |
Factors:
| F1 | Genotype:Depdc5 KO | Treatment:Control |
| F2 | Genotype:Depdc5 KO | Treatment:Fasted |
| F3 | Genotype:Depdc5 WT | Treatment:Control |
| F4 | Genotype:Depdc5 WT | Treatment:Fasted |
