Clustering data with hclust algorithm for (Study ST001349)
(Analysis AN002243)| Metabolite | Structure | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 | F10 | F11 | F12 | F13 | F14 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Spermidine | ME314378 | 1.85 | 0.66 | 0.71 | 0.84 | 0.84 | 1.59 | 1.22 | 0.98 | 0.73 | 0.53 | 0.82 | 0.90 | 0.63 | 1.54 |
| Spermine | ME314379 | 2.06 | 0.49 | 0.66 | 0.85 | 0.81 | 1.96 | 1.38 | 0.97 | 0.55 | 0.38 | 0.74 | 0.94 | 0.43 | 1.58 |
| Betaine | ME314390 | 1.85 | 0.60 | 1.08 | 0.58 | 1.56 | 0.52 | 0.88 | 0.46 | 1.38 | 0.66 | 0.83 | 0.47 | 0.77 | 0.78 |
| ProBetaine | ME314403 | 1.12 | 0.66 | 1.26 | 0.66 | 1.38 | 0.56 | 1.32 | 0.57 | 1.29 | 0.57 | 1.07 | 0.62 | 0.70 | 0.79 |
| 5-AVA | ME314384 | 0.93 | 0.54 | 0.89 | 0.55 | 1.74 | 1.01 | 1.61 | 1.16 | 0.82 | 0.56 | 0.98 | 1.05 | 0.50 | 0.71 |
| TMAO | ME314412 | 0.88 | 0.85 | 1.28 | 0.70 | 1.42 | 1.10 | 1.51 | 0.81 | 0.94 | 0.88 | 0.88 | 0.94 | 0.43 | 0.47 |
| Cortisol | ME314409 | 0.86 | 0.94 | 0.70 | 1.24 | 0.70 | 0.54 | 0.85 | 0.97 | 0.67 | 0.41 | 1.53 | 1.44 | 0.88 | 1.20 |
| c4-OH-Pro | ME314391 | 0.95 | 1.48 | 0.88 | 1.37 | 0.81 | 1.05 | 0.81 | 1.18 | 0.73 | 1.31 | 0.70 | 1.05 | 1.39 | 1.41 |
| t4-OH-Pro | ME314406 | 0.96 | 1.32 | 0.90 | 1.47 | 0.82 | 0.97 | 0.75 | 1.12 | 0.75 | 1.03 | 0.80 | 1.12 | 1.35 | 1.65 |
| TrpBetaine | ME314408 | 0.84 | 0.61 | 0.92 | 0.86 | 1.02 | 0.71 | 0.61 | 0.71 | 1.08 | 1.08 | 1.86 | 1.02 | 1.02 | 1.17 |
| Serotonin | ME314377 | 1.25 | 1.25 | 0.92 | 0.59 | 1.04 | 1.02 | 1.00 | 0.53 | 1.19 | 0.63 | 0.87 | 0.84 | 1.50 | 1.18 |
| Sarcosine | ME314404 | 0.96 | 0.93 | 0.91 | 1.19 | 0.87 | 1.19 | 0.77 | 1.00 | 0.99 | 1.66 | 0.92 | 1.18 | 1.01 | 1.00 |
| Glu | ME314359 | 0.96 | 1.24 | 0.91 | 1.03 | 0.99 | 1.46 | 1.04 | 0.99 | 0.79 | 1.14 | 0.92 | 0.99 | 1.11 | 0.85 |
| PAG | ME314402 | 0.74 | 0.94 | 0.94 | 0.85 | 1.22 | 1.47 | 1.24 | 1.04 | 0.80 | 1.05 | 1.00 | 1.05 | 0.87 | 0.86 |
| Carnosine | ME314392 | 0.85 | 1.22 | 0.82 | 0.84 | 0.84 | 1.04 | 0.90 | 0.73 | 1.06 | 1.12 | 1.38 | 1.16 | 0.91 | 1.27 |
| 3-IAA | ME314380 | 1.09 | 1.06 | 0.86 | 0.90 | 0.92 | 0.85 | 1.37 | 1.01 | 1.06 | 0.75 | 1.07 | 1.15 | 0.77 | 0.79 |
| HCys | ME314398 | 1.11 | 1.17 | 0.93 | 0.84 | 0.86 | 1.11 | 0.94 | 1.00 | 1.04 | 1.25 | 1.11 | 0.89 | 0.93 | 0.82 |
| Met-SO | ME314400 | 1.13 | 0.96 | 0.94 | 1.05 | 1.15 | 0.96 | 0.95 | 0.93 | 1.04 | 1.39 | 0.93 | 0.97 | 0.85 | 0.63 |
| HArg | ME314397 | 0.80 | 1.06 | 0.79 | 0.83 | 0.91 | 1.06 | 1.00 | 1.21 | 1.24 | 1.34 | 1.07 | 1.27 | 0.94 | 0.66 |
| Val | ME314372 | 0.86 | 1.01 | 0.79 | 0.92 | 1.05 | 1.01 | 1.00 | 1.03 | 1.15 | 1.22 | 1.03 | 1.17 | 0.95 | 0.92 |
| Ile | ME314362 | 0.92 | 1.04 | 0.82 | 0.98 | 0.98 | 1.05 | 1.01 | 1.01 | 1.20 | 1.19 | 0.94 | 1.17 | 0.93 | 0.88 |
| Lys | ME314364 | 0.92 | 1.04 | 0.85 | 0.96 | 0.99 | 1.04 | 1.02 | 0.94 | 1.13 | 1.20 | 1.03 | 1.14 | 0.95 | 0.85 |
| Arg | ME314354 | 0.87 | 1.00 | 0.87 | 1.02 | 0.93 | 0.97 | 1.02 | 1.10 | 1.18 | 1.14 | 1.05 | 1.19 | 0.89 | 0.88 |
| Leu | ME314363 | 0.89 | 1.01 | 0.81 | 0.93 | 0.97 | 0.95 | 1.01 | 1.01 | 1.27 | 1.14 | 1.02 | 1.19 | 0.94 | 0.90 |
| His | ME314361 | 0.74 | 0.78 | 0.94 | 0.89 | 1.13 | 0.80 | 1.22 | 1.00 | 1.11 | 1.04 | 1.16 | 1.09 | 0.98 | 0.83 |
| Taurine | ME314407 | 0.82 | 0.82 | 0.85 | 0.88 | 0.98 | 1.05 | 1.14 | 0.92 | 1.14 | 0.91 | 1.25 | 1.26 | 0.84 | 0.96 |
| alpha-AAA | ME314387 | 0.88 | 0.95 | 1.00 | 0.71 | 1.17 | 0.92 | 1.01 | 0.77 | 1.17 | 1.09 | 1.17 | 0.98 | 0.97 | 0.81 |
| Orn | ME314401 | 0.82 | 0.89 | 0.86 | 0.89 | 0.99 | 1.10 | 1.13 | 1.07 | 1.15 | 1.13 | 1.18 | 1.12 | 0.81 | 0.74 |
| Cys | ME314357 | 0.96 | 0.83 | 0.91 | 0.83 | 1.14 | 0.99 | 1.01 | 0.96 | 1.19 | 1.10 | 1.14 | 1.01 | 0.80 | 0.76 |
| Cystine | ME314395 | 0.87 | 0.76 | 0.87 | 0.76 | 1.15 | 1.08 | 1.07 | 0.98 | 1.27 | 1.21 | 1.25 | 0.96 | 0.67 | 0.61 |
| 1-Met-His | ME314382 | 1.21 | 1.01 | 0.97 | 0.88 | 0.90 | 0.78 | 0.94 | 0.70 | 1.02 | 1.07 | 1.13 | 1.03 | 1.13 | 1.05 |
| Choline | ME314411 | 1.10 | 0.87 | 1.01 | 0.77 | 0.96 | 0.92 | 0.87 | 0.78 | 1.16 | 1.01 | 1.01 | 0.95 | 1.13 | 1.36 |
| Asn | ME314355 | 1.20 | 1.00 | 0.93 | 1.07 | 1.05 | 0.85 | 1.03 | 1.00 | 0.93 | 1.12 | 0.94 | 1.10 | 0.90 | 0.80 |
| BABA | ME314389 | 1.24 | 0.95 | 1.12 | 1.07 | 1.13 | 0.89 | 0.92 | 0.78 | 0.85 | 1.01 | 0.97 | 1.02 | 0.85 | 0.98 |
| Ser | ME314368 | 0.97 | 1.04 | 1.06 | 0.95 | 1.05 | 0.85 | 1.02 | 0.99 | 1.14 | 0.87 | 1.07 | 0.78 | 0.96 | 0.93 |
| Asp | ME314356 | 1.08 | 0.99 | 1.09 | 0.86 | 1.08 | 1.01 | 1.04 | 0.94 | 0.84 | 0.93 | 0.98 | 1.00 | 1.04 | 1.04 |
| Kynurenine | ME314399 | 0.94 | 1.00 | 1.06 | 0.90 | 1.09 | 1.04 | 1.16 | 0.91 | 0.95 | 0.92 | 1.01 | 0.91 | 1.03 | 0.82 |
| Phe | ME314366 | 0.94 | 1.08 | 1.00 | 0.90 | 0.98 | 1.04 | 1.11 | 0.96 | 1.03 | 1.04 | 0.98 | 1.01 | 0.92 | 0.96 |
| Tyr | ME314371 | 0.98 | 0.95 | 0.95 | 0.96 | 1.06 | 1.12 | 1.12 | 1.00 | 1.06 | 1.07 | 0.96 | 1.02 | 0.80 | 0.81 |
| Cit | ME314393 | 0.92 | 0.90 | 1.00 | 0.91 | 1.07 | 0.85 | 1.04 | 0.98 | 1.15 | 0.84 | 1.08 | 1.06 | 0.90 | 1.06 |
| Pro | ME314367 | 0.88 | 0.99 | 0.91 | 1.02 | 1.07 | 0.92 | 1.07 | 0.99 | 1.13 | 0.96 | 1.10 | 0.97 | 0.90 | 0.95 |
| Gln | ME314358 | 0.97 | 1.02 | 0.98 | 1.03 | 1.03 | 0.91 | 1.06 | 0.98 | 0.99 | 0.98 | 1.07 | 1.09 | 0.97 | 0.84 |
| Trp | ME314370 | 1.02 | 0.89 | 0.95 | 0.97 | 1.02 | 0.91 | 1.05 | 1.00 | 1.11 | 1.01 | 1.06 | 1.07 | 0.88 | 0.85 |
| SDMA | ME314405 | 1.10 | 1.04 | 0.88 | 0.99 | 1.00 | 0.84 | 1.08 | 0.87 | 0.90 | 0.94 | 1.10 | 1.12 | 1.02 | 1.07 |
| ADMA | ME314386 | 0.89 | 1.04 | 0.91 | 1.02 | 1.06 | 0.99 | 1.05 | 1.09 | 0.90 | 1.01 | 0.97 | 1.16 | 0.99 | 1.12 |
| Met | ME314365 | 0.88 | 1.10 | 0.90 | 0.95 | 0.96 | 1.01 | 1.01 | 0.94 | 1.06 | 1.19 | 1.06 | 1.06 | 1.01 | 1.00 |
| Ala | ME314353 | 0.98 | 1.17 | 0.93 | 0.94 | 0.97 | 0.97 | 0.95 | 0.95 | 0.98 | 1.14 | 1.00 | 1.03 | 1.08 | 1.12 |
| beta-Ala | ME314373 | 0.95 | 1.20 | 0.93 | 1.00 | 0.97 | 0.96 | 1.02 | 0.91 | 1.00 | 1.11 | 1.03 | 0.95 | 1.09 | 1.00 |
| Thr | ME314369 | 0.98 | 1.05 | 0.95 | 1.08 | 1.09 | 0.89 | 0.99 | 0.92 | 1.06 | 1.06 | 0.93 | 0.93 | 0.98 | 1.09 |
| Cortisone | ME314410 | 1.02 | 0.94 | 0.95 | 0.94 | 0.95 | 0.95 | 0.94 | 1.00 | 1.03 | 1.01 | 1.12 | 0.95 | 1.08 | 1.08 |
| Creatinine | ME314394 | 1.09 | 1.00 | 0.98 | 0.98 | 1.04 | 0.94 | 0.95 | 0.98 | 0.98 | 0.98 | 0.95 | 1.03 | 1.04 | 1.09 |
| DOPA | ME314396 | 1.02 | 1.01 | 0.96 | 1.03 | 0.97 | 1.05 | 1.02 | 1.04 | 0.97 | 0.97 | 1.02 | 0.99 | 0.98 | 1.02 |
| Histamine | ME314375 | 1.00 | 0.98 | 1.00 | 0.99 | 1.01 | 0.99 | 1.01 | 1.01 | 0.99 | 1.01 | 1.01 | 1.01 | 1.00 | 1.01 |
| GABA | ME314374 | 1.00 | 0.91 | 0.88 | 0.82 | 1.02 | 0.99 | 1.21 | 0.93 | 1.05 | 1.08 | 0.86 | 0.97 | 1.12 | 1.14 |
| Putrescine | ME314376 | 1.14 | 0.86 | 1.01 | 1.02 | 1.02 | 1.10 | 1.00 | 0.79 | 0.89 | 1.16 | 0.86 | 1.02 | 1.19 | 1.01 |
| Gly | ME314360 | 1.03 | 0.72 | 1.22 | 0.93 | 0.97 | 0.91 | 1.15 | 1.00 | 1.00 | 0.80 | 0.91 | 1.03 | 0.91 | 1.15 |
| 3-Met-His | ME314383 | 1.12 | 1.02 | 0.92 | 0.94 | 1.14 | 0.77 | 1.12 | 0.89 | 0.99 | 0.75 | 0.87 | 1.11 | 1.02 | 1.20 |
| Anserine | ME314388 | 1.16 | 0.97 | 0.96 | 0.89 | 1.15 | 0.70 | 0.97 | 0.89 | 1.03 | 0.82 | 1.00 | 1.02 | 1.00 | 1.16 |
| 3-IPA | ME314381 | 1.41 | 1.16 | 1.08 | 1.17 | 0.80 | 1.05 | 0.77 | 0.60 | 1.32 | 1.07 | 0.84 | 0.68 | 0.98 | 0.85 |
| AABA | ME314385 | 1.22 | 1.06 | 1.16 | 1.04 | 1.10 | 0.62 | 0.86 | 0.69 | 1.13 | 0.90 | 0.68 | 0.98 | 1.03 | 1.38 |
Factors:
| F1 | Day:14 | Group:control | Parity:multiparous |
| F2 | Day:14 | Group:control | Parity:primiparous |
| F3 | Day:14 | Group:treatment | Parity:multiparous |
| F4 | Day:14 | Group:treatment | Parity:primiparous |
| F5 | Day:21 | Group:control | Parity:multiparous |
| F6 | Day:21 | Group:control | Parity:primiparous |
| F7 | Day:21 | Group:treatment | Parity:multiparous |
| F8 | Day:21 | Group:treatment | Parity:primiparous |
| F9 | Day:42 | Group:control | Parity:multiparous |
| F10 | Day:42 | Group:control | Parity:primiparous |
| F11 | Day:42 | Group:treatment | Parity:multiparous |
| F12 | Day:42 | Group:treatment | Parity:primiparous |
| F13 | Day:7 | Group:control | Parity:primiparous |
| F14 | Day:7 | Group:treatment | Parity:primiparous |