Metabolomics Workbench : NIH Data Repository

Clustering data with hclust algorithm for (Study ST002263)

(Analysis AN003696)

Metabolite	Structure	F1	F2	F3	F4	F5	F6
Glycocholic acid	ME543996	0.64	3.87	0.17	0.21	0.49	0.20
Histamine	ME543971	0.20	0.43	2.61	0.09	2.95	0.12
3-Methylglutarylcarnitine	ME543924	0.52	1.02	3.22	0.91	0.41	0.46
Benzyldimethyltetradecylammonium cation	ME544028	0.70	0.66	3.04	0.66	0.67	0.78
Adipoyl-L-carnitine	ME543892	0.92	2.00	1.74	0.33	0.50	0.70
OPHTHALMIC ACID	ME543942	1.47	2.31	0.81	0.13	1.05	0.18
Taurocholic acid	ME544026	0.90	2.46	0.61	0.85	0.57	0.52
Tauroursodeoxycholic acid	ME543890	1.46	2.64	0.46	0.46	0.52	0.32
4-Guanidinobutyric acid	ME544012	0.65	0.35	1.31	1.39	0.47	1.91
Equol	ME543881	0.18	0.25	1.23	1.50	0.22	1.88
TMAO	ME544018	0.47	0.73	1.41	0.76	2.10	0.64
2-Indolinone	ME543949	0.93	1.04	0.58	0.38	2.18	0.79
N-omega-Acetylhistamine	ME544032	1.17	1.10	0.48	0.48	2.23	0.40
Guanidinosuccinic acid	ME544021	0.40	1.16	0.86	0.58	1.87	1.10
Stachydrine	ME543894	0.71	1.18	0.46	0.74	1.83	0.94
Maltose	ME543904	0.61	1.50	0.51	0.61	1.63	1.02
Ala-Lys	ME543991	0.78	1.60	0.46	0.76	1.53	0.73
Maltotriose	ME544003	0.65	1.59	0.61	0.77	1.34	0.95
Ser-Arg	ME544004	1.16	1.78	0.76	0.31	1.39	0.55
Carnosine	ME543896	1.18	1.44	0.65	0.39	1.78	0.48
Arg-Tyr	ME544036	1.10	1.45	0.76	0.46	1.53	0.65
Gln-Thr	ME543925	1.03	1.59	0.67	0.65	1.43	0.55
His-Ala	ME543913	1.11	1.49	0.79	0.59	1.43	0.54
Arg-Ala	ME544030	0.91	1.59	0.64	0.59	1.58	0.59
Gln-Gly	ME543944	1.13	1.58	0.56	0.54	1.61	0.48
N6,N6-dimethyllysine	ME544037	1.43	1.20	1.03	0.29	1.28	0.77
1-Methyl-L-histidine	ME543891	1.41	1.29	0.90	0.56	1.33	0.48
3-Methylhistidine	ME543943	1.38	1.33	0.67	0.57	1.41	0.56
Gln-Ala	ME543907	1.00	2.03	0.56	0.31	1.70	0.29
Methacholine cation	ME543975	1.39	1.67	0.33	0.29	1.81	0.35
Palmitoylcarnitine	ME544034	1.54	0.84	1.54	0.82	0.54	0.86
Nicotinamide riboside cation	ME543946	0.90	1.05	1.65	1.17	0.86	0.54
Isomer of Taurocholic acid	ME543972	0.91	1.12	1.72	0.88	0.80	0.76
Stearoyl-L-carnitine	ME543911	1.06	1.18	1.58	0.96	0.58	0.78
Myristoyl-L-carnitine	ME543986	1.18	0.60	2.12	0.92	0.39	1.05
Decanoyl-L-carnitine	ME543963	0.86	0.89	2.07	0.77	0.69	0.99
Linoleoylcarnitine	ME543965	1.15	0.85	1.99	0.87	0.78	0.60
Oleoyl-L-carnitine	ME543940	1.23	0.84	1.95	0.99	0.45	0.78
N-Acetylhistidine	ME543951	0.99	0.50	1.26	0.93	1.16	1.23
Phosphocholine	ME544039	1.38	0.31	1.20	0.99	0.99	1.17
SEROTONIN	ME543992	0.46	0.81	1.39	0.99	1.02	1.44
Cystathionine	ME543939	0.74	0.62	1.59	1.27	0.60	1.32
NALPHA-ACETYL-L-LYSINE	ME544019	0.90	0.70	1.73	1.06	0.62	1.16
Taurine	ME544033	1.24	0.60	1.02	1.31	0.35	1.48
Hexanoyl-L-carnitine	ME544023	1.20	0.69	1.07	0.84	0.34	1.88
Octanoylcarnitine	ME543899	1.21	0.63	1.34	0.77	0.46	1.67
1-Hexadecanoyl-2-sn-glycero-3-phosphate	ME544040	0.74	1.13	0.37	0.93	0.87	1.81
1-Oleoyl-2-myristoyl-sn-glycero-3-phosphocholine	ME543955	0.84	0.61	0.54	1.22	0.76	1.91
Putrescine	ME543953	0.79	0.56	0.69	1.66	0.42	1.81
2-Methylbutyryl-L-carnitine	ME543937	0.67	0.90	0.84	1.37	0.63	1.54
Cytosine	ME543980	0.60	0.95	0.61	1.41	0.68	1.66
Propionylcarnitine; [M+H]+; HCD (NCE 20-30-40%)	ME544016	0.63	1.06	0.84	1.30	0.80	1.32
Protoporphyrin IX	ME543982	0.79	0.98	0.65	1.27	0.83	1.39
Sarcosine	ME543914	0.75	0.98	0.63	1.33	0.94	1.28
HYPOTAURINE	ME544022	0.68	0.73	1.08	1.57	0.59	1.37
NAD+	ME543887	0.90	0.64	1.26	1.12	0.73	1.42
C18+M160T67	ME544011	0.76	0.60	1.04	1.33	0.97	1.31
TRIGONELLINE	ME544031	0.73	0.56	1.13	1.28	0.97	1.36
4-IMIDAZOLEACETIC ACID	ME543985	0.76	0.73	1.02	1.05	0.91	1.52
Palmitoyleicosapentaenoyl phosphatidylcholine	ME543956	0.89	0.66	0.87	1.21	0.93	1.41
1-(1Z-Octadecenyl)-sn-glycero-3-phosphocholine	ME544025	1.80	0.91	1.08	0.46	1.19	0.58
Nudifloramide	ME543948	1.76	0.91	0.96	0.75	0.82	0.78
Glutamic acid	ME544027	1.15	1.54	1.19	0.59	1.08	0.50
L-Arachidonoylcarnitine	ME543993	1.16	1.56	1.22	0.75	0.85	0.51
Cytidine-5^-monophosphate	ME543934	1.32	1.29	1.10	0.56	0.95	0.79
3-Hydroxybutyrylcarnitine	ME544015	0.98	1.44	1.07	0.71	1.06	0.76
Uridine-5-diphosphoacetylglucosamine	ME543960	1.12	1.24	1.08	0.73	1.01	0.84
Glucose-1-phosphate	ME543930	1.12	1.35	1.03	0.68	0.89	0.94
Glucose-6-phosphate	ME543968	1.08	1.47	1.01	0.61	0.98	0.86
Ergothioneine	ME544008	1.38	1.23	0.84	0.75	0.89	0.87
L-Glutarylcarnitine	ME543974	1.37	1.50	1.00	0.66	0.74	0.73
S-Adenosyl-methionine	ME543964	0.94	1.02	1.49	0.78	0.80	1.10
N,N-Dimethylarginine	ME543973	0.85	1.00	1.35	0.92	1.09	0.87
Targinine	ME543970	0.85	0.99	1.38	0.81	1.00	1.07
5^-Methylthioadenosine	ME544029	1.06	1.05	1.23	0.87	0.99	0.86
Adenosine	ME543978	1.19	1.01	1.20	0.74	1.02	0.89
Ethanolamine	ME543931	1.32	0.92	1.21	0.96	0.87	0.77
UMP	ME543902	1.23	0.90	1.28	0.98	0.92	0.76
1-Stearoyl-2-hydroxy-sn-glycero-3-phosphocholine	ME543938	1.32	0.82	1.30	0.83	0.89	0.91
Pyridoxamine	ME543969	1.23	1.01	1.33	0.73	0.85	0.94
N-Acetyl-glutamine	ME543958	1.20	0.73	1.50	0.99	0.87	0.84
(2R)-3-Hydroxyisovaleroylcarnitine	ME543936	1.07	0.90	1.29	1.12	0.65	1.05
1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphocholine	ME543912	1.07	0.81	1.27	1.03	0.87	1.01
Acetylcarnitine	ME543995	1.09	0.95	1.39	0.92	0.78	0.96
(R)-Butyrylcarnitine	ME543990	1.17	0.93	1.21	0.94	0.52	1.29
Lysine	ME543952	0.96	1.02	1.20	1.32	0.67	0.89
Adenine	ME543917	0.80	1.12	1.09	1.06	0.76	1.19
Histidine	ME543927	0.92	0.97	1.03	1.24	0.71	1.13
N-epsilon-Acetyllysine	ME543906	0.84	0.86	1.13	1.15	0.84	1.21
gamma-Glutamyl-cysteine	ME543998	0.72	1.48	1.18	0.97	0.88	0.82
Ornithine	ME543883	0.98	1.36	0.97	0.99	0.87	0.82
S-Adenosyl-homocysteine	ME544045	1.07	1.26	1.11	1.00	0.88	0.71
3-Dehydrocarnitine	ME544041	1.03	1.56	0.68	0.80	1.05	0.79
N-Methylalanine	ME543916	1.01	1.30	0.73	0.80	1.12	0.97
Val-Arg	ME543933	1.02	1.36	0.67	0.85	1.14	0.88
4-Pyridoxic acid	ME543928	0.78	1.24	0.78	0.90	1.17	1.08
Betaine	ME543959	0.87	1.28	0.71	0.83	1.24	1.00
Tyrosine	ME543981	0.95	1.32	0.99	0.99	1.13	0.61
Inosine	ME544017	0.73	1.45	0.83	1.04	1.08	0.83
Hypoxanthine	ME543908	0.80	1.45	0.85	0.98	1.12	0.77
Pantothenic acid	ME543919	0.84	1.38	0.92	0.93	1.12	0.78
1-Oleoyl-sn-glycero-3-phosphoethanolamine	ME543987	0.91	1.20	0.74	1.01	1.15	0.92
Methionine	ME543909	0.92	1.29	0.88	1.01	1.11	0.76
2-Arachidonoylglycerol	ME543994	0.89	1.35	0.80	1.00	1.04	0.88
Carnitine	ME543983	1.00	1.30	0.79	0.95	1.01	0.88
Uracil	ME543941	0.92	1.11	0.68	1.08	1.02	1.11
Xanthosine	ME544013	0.92	1.21	0.56	1.10	1.01	1.09
1-Palmitoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine	ME544043	1.11	1.05	0.60	1.03	0.94	1.16
1-Stearoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine	ME543888	1.10	0.88	0.69	1.01	1.01	1.23
SN-GLYCERO-3-PHOSPHOCHOLINE	ME544009	0.84	0.88	1.06	1.27	1.19	0.77
Ala-Gln	ME543926	1.06	1.00	0.81	1.25	0.96	0.87
Betaine aldehyde cation	ME544010	1.07	0.91	0.83	1.36	1.04	0.76
1-Palmitoyl-sn-glycero-3-phosphocholine	ME543884	1.17	0.86	0.88	0.96	0.94	1.17
1,2-Dipalmitoleoyl-sn-glycero-3-phosphocholine	ME543920	1.00	0.77	0.82	1.09	1.02	1.25
1-Palmitoyl-2-linoleoyl-sn-glycero-3-phosphocholine	ME543947	1.02	0.81	0.91	1.01	1.08	1.14
Pipecolic acid	ME543929	1.02	0.87	0.90	1.06	1.02	1.09
2-Arachidonoyl-1-palmitoyl-sn-glycero-3-phosphoethanolamine	ME543905	0.90	0.82	0.88	1.22	1.06	1.08
2-Linoleoyl-1-palmitoyl-sn-glycero-3-phosphoethanolamine	ME543922	1.05	0.76	0.92	1.16	1.16	0.94
Choline [M]+	ME543977	0.96	0.85	1.05	1.26	0.94	0.96
3-Guanidinopropionic acid	ME543957	0.98	0.65	1.03	1.18	0.99	1.17
N,N-Diethyl-2-aminoethanol	ME543889	0.99	0.78	1.07	1.10	0.98	1.10
Glutamine	ME544044	1.11	1.07	0.89	1.07	1.03	0.80
Phenylalanine	ME543895	1.04	1.15	1.04	1.01	0.98	0.80
Tryptophan	ME543988	1.03	1.08	1.14	0.99	0.99	0.80
Riboflavin	ME543885	0.94	1.04	1.04	1.11	1.04	0.85
1-Methyladenosine	ME543918	0.89	1.10	1.17	1.04	0.96	0.87
Isoleucine	ME543882	0.95	1.05	1.14	1.10	0.95	0.85
Serine	ME543966	0.85	1.18	1.04	0.94	1.24	0.76
Adenosine 5^-diphosphoribose	ME544006	1.10	1.13	1.04	0.92	1.10	0.73
Nicotinamide	ME543901	1.05	1.17	0.97	0.97	1.09	0.75
Threonine	ME543886	1.02	1.15	1.01	0.95	1.06	0.81
Leucine	ME543999	0.95	1.10	1.01	0.99	1.14	0.81
NEPSILON,NEPSILON,NEPSILON-TRIMETHYLLYSINE	ME543967	0.99	1.16	1.03	0.92	1.17	0.75
Glutathione (reduced)	ME544002	0.99	1.22	0.87	0.87	0.98	1.05
1,2-Dihexadecanoyl-sn-glycero-3-phosphocholine	ME543954	1.11	1.01	1.02	0.82	1.03	1.01
1-Oleoyl-sn-glycero-3-phosphocholine	ME544038	1.13	1.06	0.98	0.81	1.08	0.93
AMP	ME544014	1.16	1.07	1.03	0.88	0.96	0.91
Guanosine 5^-monophosphate	ME544000	1.21	1.13	0.98	0.80	1.02	0.87
Inosine-5^-monophosphate	ME543921	1.19	1.13	0.90	0.88	0.99	0.88
1-Palmitoyl-2-docosahexaenoyl-sn-glycero-3-phosphocholine	ME543935	0.99	1.11	0.87	0.93	1.10	0.98
2-Docosahexaenoyl-1-stearoyl-sn-glycero-3-phosphoserine	ME543961	1.09	1.12	0.84	0.86	1.18	0.88
FAD	ME544024	1.11	1.14	0.88	0.81	1.11	0.92
Alanine	ME543989	0.78	1.08	0.98	0.96	1.05	1.15
Urea	ME544035	1.00	0.92	0.94	0.88	1.13	1.11
DEOXYCARNITINE	ME543945	0.90	0.91	1.10	0.99	1.02	1.11
1_Lysine-d8	ME543875	0.98	1.03	1.01	1.10	0.85	1.03
Arginine	ME543976	0.98	1.04	1.00	1.08	0.88	1.01
1,2-Dilinoleoyl-sn-glycero-3-phosphocholine	ME543915	1.05	0.96	1.05	0.97	1.08	0.90
1_CUDA	ME543870	0.99	0.93	1.02	0.96	1.07	1.03
CYTIDINE 5^-DIPHOSPHOCHOLINE	ME544005	0.99	0.92	1.01	0.99	1.12	0.97
Proline	ME543979	1.03	1.08	0.99	1.02	0.98	0.89
1_HippuricAcid-d5	ME543874	1.00	1.03	0.98	1.04	0.96	0.98
1_Tryptophan-d5	ME543880	0.97	1.05	0.97	1.03	0.98	1.00
1_Methionine_d8	ME543876	0.99	1.03	0.99	1.02	1.00	0.97
1_Serine-d8	ME543878	0.99	1.05	0.98	1.02	1.00	0.97
1_D3-1-Methylnicotinamide	ME543871	0.95	1.05	0.97	0.95	1.02	1.05
1_D9-Choline iSTD	ME543872	0.98	1.04	0.98	0.94	1.04	1.01
1_Glutamine_d5	ME543873	0.99	1.02	0.98	0.97	1.02	1.02
1_TMAO_d9	ME543879	0.98	1.02	1.00	0.97	1.02	1.01
1_Carnitine_d3	ME543869	1.01	0.98	1.02	0.98	1.02	0.99
1_Acetylcarnitine_d3	ME543868	1.00	1.00	1.03	1.00	0.97	1.01
1_Phenylalanine-d8	ME543877	0.98	1.00	0.99	1.00	0.99	1.03
1-Heptadecanoyl-sn-glycero-3-phosphocholine	ME544007	1.36	0.93	1.10	0.74	1.18	0.71
Palmitoyl sphingomyelin	ME544001	1.33	1.05	1.01	0.74	1.18	0.70
Aspartic acid	ME543893	1.30	1.08	1.18	0.57	1.18	0.74
1-Hexadecyl-sn-glycero-3-phosphocholine	ME544020	1.37	1.03	1.13	0.71	1.06	0.74
N-Acetyl-D-lactosamine	ME543923	1.41	1.09	1.23	0.64	1.02	0.67
N-Methyllysine	ME543984	1.23	0.99	0.98	0.65	1.22	0.93
1-Palmitoyl-2-arachidonoyl-sn-glycero-3-phosphoserine	ME543903	1.22	0.85	1.11	0.80	1.11	0.94
Citrulline	ME543997	1.19	0.86	1.05	0.88	1.24	0.79
Creatinine	ME543900	1.12	0.94	0.98	0.81	1.23	0.92
Thiamine Cation	ME543950	0.88	1.25	0.80	0.78	1.47	0.78
Glutathione (oxidized)	ME544042	1.05	1.12	0.80	0.69	1.37	0.91
N-Methylproline	ME543898	1.11	1.14	0.61	0.84	1.34	0.86
1,2-Diarachidonoyl-sn-glycero-3-phosphocholine	ME543962	0.96	1.10	1.18	0.77	1.34	0.70
Creatine	ME543897	1.07	1.21	1.00	0.71	1.28	0.74
1-Methylhistamine	ME543910	1.10	1.08	1.07	0.66	1.53	0.57
Thiamine monophosphate	ME543932	1.20	1.26	0.95	0.68	1.41	0.49

Factors:

F1	Genotype:Klb Knockout \| Treatment:ad libitum feeding
F2	Genotype:Klb Knockout \| Treatment:intermittent fasting
F3	Genotype:Tbx3 Knockout \| Treatment:ad libitum feeding
F4	Genotype:Tbx3 Knockout \| Treatment:intermittent fasting
F5	Genotype:Wild-type \| Treatment:ad libitum feeding
F6	Genotype:Wild-type \| Treatment:intermittent fasting

Data matrix