Data for (Study ST001411)

(Analysis AN002361)

Values for each metabolite have been scaled by dividing by the mean across all factors

Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study

Metabolite	F1	F2	F3
10-heptadecenoate (17:1n7)	1.0780	0.9746	0.7222
10-hydroxywarfarin	0.9645	1.1206	0.5325
10-nonadecenoate (19:1n9)	1.0371	0.9829	0.8955
10-undecenoate (11:1n1)	0.9595	1.0227	1.0922
11beta-hydroxyandrosterone glucuronide	0.9200	1.1303	0.7169
1-(1-enyl-oleoyl)-GPE (P-18:1)*	1.0467	0.9064	1.2605
1-(1-enyl-palmitoyl)-2-arachidonoyl-GPC (P-16:0/20:4)*	0.9465	1.0312	1.1152
1-(1-enyl-palmitoyl)-2-arachidonoyl-GPE (P-16:0/20:4)*	0.9724	1.0285	0.9919
1-(1-enyl-palmitoyl)-2-linoleoyl-GPC (P-16:0/18:2)*	0.9209	0.9694	1.5888
1-(1-enyl-palmitoyl)-2-linoleoyl-GPE (P-16:0/18:2)*	0.9869	0.9944	1.1009
1-(1-enyl-palmitoyl)-2-oleoyl-GPC (P-16:0/18:1)*	0.9317	0.9766	1.4916
1-(1-enyl-palmitoyl)-2-oleoyl-GPE (P-16:0/18:1)*	0.9878	1.0008	1.0607
1-(1-enyl-palmitoyl)-2-palmitoleoyl-GPC (P-16:0/16:1)*	0.9860	0.9783	1.1930
1-(1-enyl-palmitoyl)-2-palmitoyl-GPC (P-16:0/16:0)*	0.9406	0.9877	1.3836
1-(1-enyl-palmitoyl)-GPC (P-16:0)*	0.9429	0.9355	1.6554
1-(1-enyl-palmitoyl)-GPE (P-16:0)*	1.0067	1.0057	0.9331
1-(1-enyl-stearoyl)-2-arachidonoyl-GPE (P-18:0/20:4)*	0.9704	1.0218	1.0391
1-(1-enyl-stearoyl)-2-linoleoyl-GPE (P-18:0/18:2)*	0.9579	0.9678	1.4003
1-(1-enyl-stearoyl)-2-oleoyl-GPE (P-18:0/18:1)	0.9778	1.0001	1.1177
1-(1-enyl-stearoyl)-GPE (P-18:0)*	0.9978	0.9275	1.4063
12,13-DiHOME	1.0212	1.0282	0.7332
1,2,3-benzenetriol sulfate (2)	1.0743	0.9707	0.7627
1,2-dilinoleoyl-GPC (18:2/18:2)	0.9300	0.9154	1.8340
1,2-dilinoleoyl-GPE (18:2/18:2)*	1.1765	0.8880	0.6684
1,2-dipalmitoyl-GPC (16:0/16:0)	0.9913	0.9885	1.1091
(12 or 13)-methylmyristate (a15:0 or i15:0)	0.9899	1.0301	0.8902
1,3,7-trimethylurate	0.9799	1.1244	0.4297
1,3-dimethylurate	0.9658	1.0583	0.8651
13-HODE + 9-HODE	0.9921	1.0429	0.8082
14-HDoHE/17-HDoHE	0.8365	1.0265	1.7277
(14 or 15)-methylpalmitate (a17:0 or i17:0)	1.0224	0.9877	0.9473
1,5-anhydroglucitol (1,5-AG)	0.8879	1.0254	1.4594
16a-hydroxy DHEA 3-sulfate	0.8449	1.2435	0.5016
16-hydroxypalmitate	1.0288	1.0130	0.7755
(16 or 17)-methylstearate (a19:0 or i19:0)	0.9864	1.0055	1.0428
1,7-dimethylurate	0.9644	1.0698	0.8098
1-arachidonoyl-GPC (20:4n6)*	1.0463	0.9521	1.0140
1-arachidonoyl-GPE (20:4n6)*	1.0128	1.0020	0.9206
1-arachidonoyl-GPI (20:4)*	1.0256	0.9696	1.0291
1-arachidonylglycerol (20:4)	1.0508	1.0088	0.6814
1-carboxyethylisoleucine	1.0673	1.0772	0.2205
1-carboxyethylleucine	1.0691	1.0626	0.2911
1-carboxyethylphenylalanine	1.0344	1.0980	0.2831
1-carboxyethyltyrosine	1.0493	1.0927	0.2323
1-carboxyethylvaline	1.0642	1.0761	0.2432
1-dihomo-linolenylglycerol (20:3)	1.0464	1.0190	0.6491
1-docosahexaenoylglycerol (22:6)	1.0333	0.9800	0.9312
1H-indole-7-acetic acid	0.9705	1.0362	0.9601
1-linolenoylglycerol (18:3)	0.9986	1.0079	0.9645
1-linolenoyl-GPC (18:3)*	0.9715	0.9918	1.1962
1-linoleoyl-2-linolenoyl-GPC (18:2/18:3)*	0.8915	0.9270	1.9762
1-linoleoylglycerol (18:2)	1.1116	0.9267	0.8037
1-linoleoyl-GPA (18:2)*	1.0074	0.9492	1.2371
1-linoleoyl-GPC (18:2)	0.9732	0.9748	1.2798
1-linoleoyl-GPE (18:2)*	0.9872	0.9589	1.2922
1-linoleoyl-GPG (18:2)*	1.0570	0.9455	0.9930
1-linoleoyl-GPI (18:2)*	1.0336	0.9003	1.3635
1-methyl-4-imidazoleacetate	0.9879	1.0441	0.8243
1-methyl-5-imidazoleacetate	0.8911	1.1681	0.6656
1-methylhistidine	0.9167	1.0618	1.1076
1-methylnicotinamide	0.9850	0.9842	1.1662
1-methylurate	1.0311	0.9794	0.9467
1-methylxanthine	0.9057	1.1269	0.8119
1-myristoyl-2-arachidonoyl-GPC (14:0/20:4)*	0.9382	1.0776	0.9070
1-myristoyl-2-palmitoyl-GPC (14:0/16:0)	0.9678	1.0237	1.0430
1-oleoyl-2-arachidonoyl-GPE (18:1/20:4)*	1.0929	0.9544	0.7530
1-oleoyl-2-docosahexaenoyl-GPC (18:1/22:6)*	0.9527	0.9913	1.2994
1-oleoyl-2-docosahexaenoyl-GPE (18:1/22:6)*	1.0919	0.9630	0.7113
1-oleoyl-2-linoleoyl-GPE (18:1/18:2)*	1.0856	0.9324	0.9115
1-oleoylglycerol (18:1)	1.1030	0.9406	0.7740
1-oleoyl-GPC (18:1)	0.9834	0.9832	1.1801
1-oleoyl-GPE (18:1)	1.0336	0.9608	1.0343
1-oleoyl-GPG (18:1)*	0.9961	0.9654	1.2092
1-oleoyl-GPI (18:1)	1.0140	0.9231	1.3441
1-oleoyl-GPS (18:1)	0.9804	1.0016	1.0957
1-palmitoleoylglycerol (16:1)*	1.0534	0.9415	1.0337
1-palmitoleoyl-GPC (16:1)*	0.9930	1.0085	0.9912
1-palmitoyl-2-arachidonoyl-GPC (16:0/20:4n6)	0.9913	1.0154	0.9627
1-palmitoyl-2-arachidonoyl-GPE (16:0/20:4)*	1.0580	0.9825	0.7860
1-palmitoyl-2-arachidonoyl-GPI (16:0/20:4)*	0.9655	1.0325	1.0070
1-palmitoyl-2-dihomo-linolenoyl-GPC (16:0/20:3n3 or 6)*	0.9920	1.0056	1.0123
1-palmitoyl-2-docosahexaenoyl-GPC (16:0/22:6)	0.9421	1.0210	1.1947
1-palmitoyl-2-docosahexaenoyl-GPE (16:0/22:6)*	1.0534	0.9837	0.8038
1-palmitoyl-2-linoleoyl-GPC (16:0/18:2)	0.9769	0.9889	1.1834
1-palmitoyl-2-linoleoyl-GPE (16:0/18:2)	1.0635	0.9535	0.9145
1-palmitoyl-2-linoleoyl-GPI (16:0/18:2)	0.9988	0.8992	1.5551
1-palmitoyl-2-oleoyl-GPC (16:0/18:1)	0.9819	1.0039	1.0752
1-palmitoyl-2-oleoyl-GPE (16:0/18:1)	1.0898	0.9549	0.7664
1-palmitoyl-2-oleoyl-GPI (16:0/18:1)*	1.0224	0.9111	1.3641
1-palmitoyl-2-palmitoleoyl-GPC (16:0/16:1)*	1.0255	1.0129	0.7938
1-palmitoyl-2-stearoyl-GPC (16:0/18:0)	0.9776	0.9670	1.2996
1-palmitoyl-2-stearoyl-GPE (16:0/18:0)*	1.0703	0.9631	0.8259
1-palmitoyl-GPA (16:0)	1.0201	0.8744	1.5768
1-palmitoyl-GPC (16:0)	0.9712	0.9891	1.2127
1-palmitoyl-GPE (16:0)	0.9957	0.9809	1.1267
1-palmitoyl-GPG (16:0)*	1.0782	0.9313	0.9570
1-palmitoyl-GPI (16:0)	1.0488	0.8964	1.3039
1-ribosyl-imidazoleacetate*	1.0213	1.0147	0.8063
1-stearoyl-2-arachidonoyl-GPC (18:0/20:4)	0.9777	1.0298	0.9567
1-stearoyl-2-arachidonoyl-GPE (18:0/20:4)	1.0368	0.9881	0.8683
1-stearoyl-2-arachidonoyl-GPI (18:0/20:4)	0.9716	0.9985	1.1597
1-stearoyl-2-arachidonoyl-GPS (18:0/20:4)	1.0101	0.9900	1.0006
1-stearoyl-2-docosahexaenoyl-GPC (18:0/22:6)	0.9315	1.0313	1.1951
1-stearoyl-2-docosahexaenoyl-GPE (18:0/22:6)*	1.0741	0.9916	0.6509
1-stearoyl-2-linoleoyl-GPC (18:0/18:2)*	0.9744	0.9844	1.2217
1-stearoyl-2-linoleoyl-GPE (18:0/18:2)*	1.0610	0.9613	0.8858
1-stearoyl-2-linoleoyl-GPI (18:0/18:2)	0.9789	0.9039	1.6357
1-stearoyl-2-oleoyl-GPC (18:0/18:1)	0.9773	0.9939	1.1541
1-stearoyl-2-oleoyl-GPE (18:0/18:1)	1.0808	0.9664	0.7519
1-stearoyl-2-oleoyl-GPI (18:0/18:1)*	0.9860	0.8801	1.7273
1-stearoyl-2-oleoyl-GPS (18:0/18:1)	1.0079	0.9608	1.1713
1-stearoyl-GPC (18:0)	0.9510	1.0004	1.2592
1-stearoyl-GPE (18:0)	1.0118	0.9760	1.0677
1-stearoyl-GPG (18:0)	1.0989	0.9129	0.9465
1-stearoyl-GPI (18:0)	1.0504	0.9216	1.1576
1-stearoyl-GPS (18:0)*	1.0737	0.9253	1.0133
21-hydroxypregnenolone disulfate	0.8723	1.0863	1.2110
2,3-dihydroxy-2-methylbutyrate	1.0036	1.0327	0.8024
2,3-dihydroxy-5-methylthio-4-pentenoate (DMTPA)*	0.9852	1.0260	0.9376
2,3-dihydroxyisovalerate	1.0025	0.9613	1.1974
(2,4 or 2,5)-dimethylphenol sulfate	1.0974	1.0362	0.2835
2,6-dihydroxybenzoic acid	1.0423	0.9430	1.0845
2-acetamidophenol sulfate	1.0834	0.8415	1.4179
2-aminoadipate	1.0191	1.0617	0.5624
2-aminobutyrate	0.9743	1.0223	1.0159
2-aminoheptanoate	1.0872	0.9491	0.8123
2-aminooctanoate	0.9535	0.9886	1.3105
2-aminophenol sulfate	1.0417	0.9399	1.1048
2-arachidonoylglycerol (20:4)	0.8655	1.1191	1.0687
(2-butoxyethoxy)acetic acid	0.9189	1.1238	0.7585
2^-deoxyuridine	0.9831	0.9687	1.2605
2-ethylphenylsulfate	1.2316	0.8936	0.3441
2-hydroxy-3-methylvalerate	0.9929	1.0505	0.7625
2-hydroxy-4-(methylthio)butanoic acid	0.9382	1.0342	1.1435
2-hydroxyacetaminophen sulfate*	1.0202	1.1165	0.2582
2-hydroxyadipate	0.9112	1.1617	0.5933
2-hydroxybutyrate/2-hydroxyisobutyrate	0.9988	1.0577	0.6926
2-hydroxydecanoate	1.0362	0.9841	0.8936
2-hydroxyglutarate	0.9863	0.9896	1.1293
2-hydroxyhippurate (salicylurate)	1.3409	0.8465	0.0175
2-hydroxyibuprofen	1.4194	0.5542	1.1902
2-hydroxylaurate	0.9820	1.0109	1.0367
2-hydroxynervonate*	1.0030	1.0140	0.9077
2-hydroxyoctanoate	0.9281	0.9963	1.4037
2-hydroxypalmitate	0.9867	0.9857	1.1486
2-hydroxyphenylacetate	0.9303	1.0811	0.9298
2-hydroxysebacate	1.0836	0.9638	0.7508
2-hydroxystearate	0.9722	1.0130	1.0777
2-keto-3-deoxy-gluconate	1.0662	0.9574	0.8792
2-ketocaprylate	0.9406	1.0100	1.2622
2-linoleoylglycerol (18:2)	1.0073	0.9560	1.2003
2-methoxyacetaminophen glucuronide*	1.1069	1.0313	0.2590
2-methoxyacetaminophen sulfate*	0.9102	1.2422	0.1603
2-methylbutyrylcarnitine (C5)	0.9888	1.0348	0.8704
2-naphthol sulfate	0.8967	1.1647	0.6544
2-oleoylglycerol (18:1)	1.1532	0.8648	0.9192
2^-O-methylcytidine	0.9860	0.9720	1.2270
2^-O-methyluridine	1.1590	0.8245	1.1072
(2 or 3)-decenoate (10:1n7 or n8)	0.9562	1.0367	1.0337
2-oxoarginine*	0.9871	1.0796	0.6350
2-palmitoleoyl-GPC (16:1)*	1.0244	0.9748	1.0066
2-palmitoyl-GPC (16:0)*	1.0705	0.9015	1.1602
2-piperidinone	1.2863	0.7977	0.5741
2R,3R-dihydroxybutyrate	0.9606	1.0520	0.9271
2S,3R-dihydroxybutyrate	0.9647	1.0382	0.9802
2-stearoyl-GPE (18:0)*	1.0071	0.9455	1.2588
3-(3-amino-3-carboxypropyl)uridine*	1.0286	0.9932	0.8846
3-(3-hydroxyphenyl)propionate	0.8626	1.1553	0.8874
3-(3-hydroxyphenyl)propionate sulfate	0.8538	1.1195	1.1291
3,4-dihydroxybutyrate	1.0230	1.0262	0.7349
3-(4-hydroxyphenyl)lactate	0.9579	1.0233	1.0975
3,4-methyleneheptanoate	0.9489	0.9945	1.3029
3,5-dichloro-2,6-dihydroxybenzoic acid	0.9225	1.0974	0.8830
3,7-dimethylurate	1.1067	0.8602	1.1918
3-acetylphenol sulfate	0.9913	1.0675	0.6793
3-amino-2-piperidone	1.0377	0.9782	0.9177
3-aminoisobutyrate	0.9795	0.9944	1.1397
3beta-hydroxy-5-cholestenoate	0.9676	0.9283	1.5634
3b-hydroxy-5-cholenoic acid	0.9289	1.0532	1.0895
3-bromo-5-chloro-2,6-dihydroxybenzoic acid*	0.8688	1.1302	0.9907
3-carboxy-4-methyl-5-pentyl-2-furanpropionate (3-CMPFP)**	0.8918	1.0682	1.2060
3-carboxy-4-methyl-5-propyl-2-furanpropanoate (CMPF)	0.7605	1.1925	1.2296
3-(cystein-S-yl)acetaminophen*	1.0133	1.1045	0.3600
3-decenoylcarnitine	0.9324	0.9926	1.4007
3-ethylcatechol sulfate (1)	0.9744	1.0915	0.6384
3-formylindole	0.9174	1.0791	1.0095
3-hydroxy-2-ethylpropionate	0.9713	1.0438	0.9147
3-hydroxy-2-methylpyridine sulfate	1.0366	1.1064	0.2250
3-hydroxy-3-methylglutarate	1.1232	0.9552	0.5866
3-hydroxyadipate*	1.0270	1.0731	0.4583
3-hydroxybutyrate (BHBA)	1.1332	0.9091	0.7846
3-hydroxybutyroylglycine**	1.0303	1.0001	0.8379
3-hydroxycotinine glucuronide	1.0079	1.0496	0.6880
3-hydroxydecanoate	0.9623	1.0973	0.6710
3-hydroxydecanoylcarnitine	0.9698	0.9314	1.5351
3-hydroxydodecanedioate*	1.1642	0.9445	0.4268
3-hydroxyhexanoate	1.0145	1.0137	0.8479
3-hydroxyhexanoylcarnitine (1)	1.0069	0.9809	1.0670
3-hydroxyhippurate	0.9310	1.0959	0.8461
3-hydroxyhippurate sulfate	0.9592	1.1000	0.6732
3-hydroxyindolin-2-one sulfate	1.0870	0.9746	0.6743
3-hydroxyisobutyrate	1.0074	1.0419	0.7325
3-hydroxylaurate	0.9403	1.0778	0.8947
3-hydroxymyristate	0.9559	1.0717	0.8447
3-hydroxyoctanoate	0.9769	1.1084	0.5330
3-hydroxyoleoylcarnitine	1.0279	0.9557	1.0922
3-hydroxyphenylacetoylglutamine	1.0268	1.0106	0.7998
3-hydroxypyridine glucuronide	1.0179	1.1323	0.1845
3-hydroxypyridine sulfate	1.0059	1.0820	0.5218
3-hydroxysebacate	1.1349	0.9761	0.4104
3-hydroxystachydrine*	1.1085	1.0079	0.3784
3-hydroxystearate	1.0591	0.9548	0.9304
3-indoleglyoxylic acid	0.9936	0.9677	1.2099
3-indoxyl sulfate	0.9931	1.0452	0.7905
3-methoxycatechol sulfate (1)	1.0538	1.0097	0.6602
3-methoxycatechol sulfate (2)	0.9617	1.0567	0.8954
3-methoxytyrosine	0.9690	0.9892	1.2245
3-methyl-2-oxobutyrate	0.9807	1.0361	0.9065
3-methyl-2-oxovalerate	0.9720	1.0462	0.8982
3-methyladipate	0.9273	1.0346	1.1995
3-methyl catechol sulfate (1)	0.9258	1.1364	0.6533
3-methyl catechol sulfate (2)	0.9303	1.1646	0.4752
3-methylcytidine	0.9752	0.9928	1.1715
3-methylglutaconate	1.0274	1.0443	0.6128
3-methylglutarylcarnitine (2)	0.8888	1.1622	0.7100
3-methylhistidine	0.8827	1.1860	0.6129
3-(methylthio)acetaminophen sulfate*	0.9856	1.1264	0.3889
3-methylxanthine	1.0030	0.9706	1.1443
3-(N-acetyl-L-cystein-S-yl) acetaminophen	0.9878	1.1324	0.3442
3-phenylpropionate (hydrocinnamate)	0.8851	0.9806	1.7182
3-phosphoglycerate	1.0150	0.9684	1.0919
3-ureidopropionate	1.0466	0.9694	0.9183
4-acetamidobutanoate	1.0156	1.0021	0.9052
4-acetamidophenol	1.1672	0.9732	0.2540
4-acetamidophenylglucuronide	1.3896	0.7623	0.2165
4-acetaminophen sulfate	1.1629	0.9843	0.2167
4-acetylcatechol sulfate (1)	1.0314	1.0041	0.8099
4-acetylphenol sulfate	1.0151	0.9850	1.0013
4-allylcatechol sulfate	1.1125	0.8639	1.1410
4-allylphenol sulfate	1.0647	0.9028	1.1844
4-cholesten-3-one	1.0290	0.9780	0.9650
4-ethylcatechol sulfate	0.9777	1.0806	0.6798
4-ethylphenylsulfate	0.9249	0.9383	1.7366
4-guanidinobutanoate	1.1124	0.9320	0.7710
4-hydroxy-2-oxoglutaric acid	0.9681	1.0547	0.8724
4-hydroxychlorothalonil	0.9905	0.9316	1.4231
4-hydroxycoumarin	1.1704	0.8385	0.9707
4-hydroxyglutamate	1.0556	1.0581	0.3870
4-hydroxyhippurate	1.1215	0.9488	0.6306
4-hydroxyphenylacetate	1.0357	1.0532	0.5198
4-hydroxyphenylacetylglutamine	1.0722	1.0124	0.5472
4-hydroxyphenylpyruvate	1.0137	1.0267	0.7819
4-imidazoleacetate	1.0779	0.9642	0.7793
4-methoxyphenol sulfate	1.0025	0.9653	1.1761
4-methyl-2-oxopentanoate	0.9582	1.0572	0.9113
4-methylbenzenesulfonate	0.9773	1.0028	1.1058
4-methylcatechol sulfate	0.9498	0.9648	1.4596
4-methylguaiacol sulfate	0.9318	1.0369	1.1630
4-methylhexanoylglutamine	1.1258	0.8752	1.0087
4-vinylguaiacol sulfate	0.8835	1.2599	0.2062
4-vinylphenol sulfate	0.8480	1.1529	0.9781
5,6-dihydrothymine	0.9777	1.0000	1.1189
5,6-dihydrouracil	0.9588	0.9934	1.2555
5,6-dihydrouridine	1.0115	1.0020	0.9280
5-acetylamino-6-amino-3-methyluracil	0.9097	1.1090	0.8881
5-acetylamino-6-formylamino-3-methyluracil	0.8759	1.1810	0.6762
5alpha-androstan-3alpha,17beta-diol disulfate	1.0123	0.9507	1.2027
5alpha-androstan-3alpha,17beta-diol monosulfate (1)	1.1233	0.8380	1.2245
5alpha-androstan-3alpha,17beta-diol monosulfate (2)	0.9655	0.9683	1.3561
5alpha-androstan-3beta,17alpha-diol disulfate	0.8041	1.0008	2.0407
5alpha-androstan-3beta,17beta-diol disulfate	0.9250	1.0390	1.1878
5alpha-androstan-3beta,17beta-diol monosulfate (2)	1.0479	0.9132	1.2175
5alpha-pregnan-3beta,20alpha-diol disulfate	0.9053	1.0820	1.0586
5alpha-pregnan-3beta,20alpha-diol monosulfate (2)	0.8957	1.0388	1.3451
5alpha-pregnan-3beta,20beta-diol monosulfate (1)	0.9515	0.9705	1.4193
5-dodecenoate (12:1n7)	0.9881	1.0239	0.9332
5-dodecenoylcarnitine (C12:1)	0.9877	0.9785	1.1827
5-(galactosylhydroxy)-L-lysine	1.0905	0.9339	0.8771
5-hydroxy-2-methylpyridine sulfate	1.0691	1.0809	0.1912
5-hydroxyhexanoate	1.0541	0.9909	0.7606
5-hydroxyindoleacetate	1.0080	1.0420	0.7289
5-hydroxyindole sulfate	0.9268	1.0679	1.0207
5-hydroxylysine	1.0629	0.9720	0.8167
5-methylthioadenosine (MTA)	1.0046	1.0303	0.8106
5-methyluridine (ribothymidine)	0.9906	0.9751	1.1854
5-oxoproline	1.0050	0.9831	1.0653
6-bromotryptophan	0.9495	1.0389	1.0572
6-hydroxyindole sulfate	0.9609	1.0729	0.8118
6-oxopiperidine-2-carboxylate	1.0094	1.0506	0.6740
7-alpha-hydroxy-3-oxo-4-cholestenoate (7-Hoca)	1.0519	0.9862	0.7987
7-hydroxywarfarin	1.0085	1.0115	0.8923
7-methylguanine	1.0117	0.9780	1.0576
7-methylurate	1.0320	0.9710	0.9871
7-methylxanthine	1.0294	0.9165	1.2978
8-methoxykynurenate	0.9888	1.0476	0.8008
acesulfame	0.4792	1.5400	0.8377
acetoacetate	1.0101	0.9456	1.2423
acetylcarnitine (C2)	0.9779	1.0066	1.0823
acisoga	1.0274	1.0188	0.7513
aconitate [cis or trans]	0.9840	1.0406	0.8645
adenine	1.0079	1.0483	0.6949
adenosine	1.0283	1.0116	0.7863
adenosine 5^-diphosphoribose (ADP-ribose)	0.9317	1.0130	1.2933
adenosine 5^-monophosphate (AMP)	0.9963	0.9897	1.0758
adipoylcarnitine (C6-DC)	0.9796	1.0318	0.9358
adrenate (22:4n6)	1.0615	0.9972	0.6871
alanine	0.9957	1.0408	0.8008
allantoin	0.9898	1.0121	0.9889
allopurinol	1.0135	0.9888	0.9888
allopurinol riboside	1.0210	0.9826	0.9826
alpha-hydroxycaproate	1.1510	0.9070	0.7014
alpha-hydroxyisocaproate	0.9600	1.0468	0.9587
alpha-hydroxyisovalerate	0.9877	1.0628	0.7235
alpha-ketobutyrate	0.9849	1.0535	0.7895
alpha-ketoglutaramate*	1.0156	0.9714	1.0725
alpha-ketoglutarate	1.0173	1.0313	0.7376
alpha-tocopherol	0.9944	0.9554	1.2724
androstenediol (3alpha, 17alpha) monosulfate (2)	0.9239	1.0494	1.1371
androstenediol (3alpha, 17alpha) monosulfate (3)	1.0130	0.9184	1.3749
androstenediol (3beta,17beta) disulfate (1)	0.8543	1.1619	0.8955
androstenediol (3beta,17beta) disulfate (2)	0.9013	1.0808	1.0863
androstenediol (3beta,17beta) monosulfate (1)	0.9776	1.0119	1.0550
androstenediol (3beta,17beta) monosulfate (2)	0.9248	1.0476	1.1419
andro steroid monosulfate C19H28O6S (1)*	0.8765	1.2046	0.5452
androsterone glucuronide	0.9284	0.9933	1.4185
androsterone sulfate	1.0348	0.8802	1.4668
anthranilate	1.0401	1.0031	0.7693
arabinose	1.1320	0.9053	0.8119
arabitol/xylitol	1.0279	0.9929	0.8898
arabonate/xylonate	1.0155	0.9877	0.9841
arachidate (20:0)	1.0324	0.9615	1.0365
arachidonate (20:4n6)	1.0362	0.9973	0.8215
arachidonoylcarnitine (C20:4)	0.9682	0.9848	1.2523
arachidonoylcholine	1.0164	0.9931	0.9502
arachidoylcarnitine (C20)*	0.8775	0.9550	1.8983
argininate*	1.0307	0.9877	0.9033
arginine	0.9651	0.9825	1.2817
ascorbic acid 2-sulfate	0.9959	1.0172	0.9280
ascorbic acid 3-sulfate*	0.9799	1.0251	0.9707
asparagine	0.9823	1.0030	1.0777
aspartate	0.9867	1.0299	0.9078
atenolol	0.9791	1.0292	0.9526
azelate (C9-DC)	0.9990	1.0230	0.8806
behenoylcarnitine (C22)*	0.9361	0.9829	1.4339
behenoyl dihydrosphingomyelin (d18:0/22:0)*	0.9721	1.0311	0.9795
behenoyl sphingomyelin (d18:1/22:0)*	0.9566	0.9939	1.2650
benzoate	1.0504	0.9593	0.9531
benzoylcarnitine*	1.0090	0.9212	1.3810
beta-alanine	1.0149	1.0010	0.9154
beta-citrylglutamate	0.9750	1.0234	1.0064
beta-cryptoxanthin	0.8799	0.9322	2.0095
beta-hydroxyisovalerate	0.9564	1.0620	0.8948
beta-hydroxyisovaleroylcarnitine	0.9898	1.0088	1.0067
betaine	1.0229	0.9647	1.0701
bilirubin (E,E)*	0.9731	0.9207	1.5753
bilirubin (E,Z or Z,E)*	0.9154	1.0006	1.4480
bilirubin (Z,Z)	0.9256	0.9929	1.4352
biliverdin	0.9264	0.9383	1.7281
branched chain 14:0 dicarboxylic acid**	0.8475	1.0264	1.6696
branched-chain, straight-chain, or cyclopropyl 10:1 fatty acid (1)*	0.9905	1.0162	0.9622
branched-chain, straight-chain, or cyclopropyl 10:1 fatty acid (2)*	0.9851	1.0269	0.9333
branched-chain, straight-chain, or cyclopropyl 10:1 fatty acid (3)*	1.0039	0.9662	1.1634
branched-chain, straight-chain, or cyclopropyl 12:1 fatty acid*	0.9711	1.0303	0.9893
butyrate (4:0)	1.0069	1.0192	0.8587
butyrylcarnitine (C4)	0.9123	1.0643	1.1178
butyrylglycine	1.0517	0.9510	0.9908
caffeic acid sulfate	0.9667	1.1865	0.1622
caffeine	0.9927	1.0613	0.7054
campesterol	0.8675	1.0088	1.6585
caprate (10:0)	0.9385	1.1064	0.7487
caproate (6:0)	0.8762	1.1526	0.8295
caprylate (8:0)	0.9691	1.0782	0.7395
carboxyethyl-GABA	0.9943	1.0172	0.9364
carboxyibuprofen	1.2804	0.7163	1.0493
carnitine	0.9608	1.0222	1.0880
carnitine of C10H14O2 (5)*	0.9965	1.0293	0.8591
carotene diol (1)	0.9118	0.9145	1.9360
carotene diol (2)	0.9075	0.9209	1.9239
carotene diol (3)	0.7754	1.0255	2.0587
catechol sulfate	0.9706	0.9774	1.2803
ceramide (d16:1/24:1, d18:1/22:1)*	0.9527	1.0201	1.1428
ceramide (d18:1/14:0, d16:1/16:0)*	1.0261	0.9567	1.0964
ceramide (d18:1/17:0, d17:1/18:0)*	0.9918	0.9981	1.0542
ceramide (d18:1/20:0, d16:1/22:0, d20:1/18:0)*	0.9734	0.9951	1.1690
ceramide (d18:2/24:1, d18:1/24:2)*	0.9211	0.9999	1.4211
cerotoylcarnitine (C26)*	0.8811	1.0211	1.5194
cetirizine	0.9997	1.0003	0.9997
C-glycosyltryptophan	1.0161	0.9901	0.9681
chenodeoxycholate	1.0284	1.0166	0.7583
chenodeoxycholic acid sulfate (1)	0.9971	1.0892	0.5303
cholate	1.0986	0.9468	0.7642
cholesterol	0.9403	0.9825	1.4137
choline	1.0278	0.9815	0.9526
choline phosphate	0.9865	0.9996	1.0740
cinnamoylglycine	1.1240	0.7747	1.5653
cis-4-decenoate (10:1n6)*	1.0140	0.9733	1.0706
cis-4-decenoylcarnitine (C10:1)	0.9940	0.9649	1.2233
cis-urocanate	0.9835	1.0441	0.8482
citalopram N-oxide*	0.9947	1.0114	0.9659
citalopram propionate*	1.0182	0.9890	0.9628
citraconate/glutaconate	1.0395	1.0539	0.4961
citramalate	1.0144	1.0079	0.8803
citrate	0.9616	1.0241	1.0735
citrulline	0.9778	0.9705	1.2788
cortisol	0.9894	0.9614	1.2669
cortisone	0.9696	0.9930	1.2002
cortolone glucuronide (1)	0.9533	1.0924	0.7459
cotinine	0.8653	1.2733	0.2302
cotinine N-oxide	1.0285	1.0261	0.7057
creatine	0.9931	1.0454	0.7896
creatinine	0.9669	1.0163	1.0877
cys-gly, oxidized	0.9935	0.9717	1.1888
cystathionine	0.9256	1.1519	0.5698
cysteine	0.9715	1.0316	0.9799
cysteine-glutathione disulfide	1.0008	0.9812	1.0978
cysteine s-sulfate	1.0212	0.9949	0.9148
cysteine sulfinic acid	1.0113	1.0273	0.7911
cysteinylglycine	1.0146	0.9884	0.9851
cysteinylglycine disulfide*	0.9793	1.0066	1.0747
cystine	0.9763	1.0332	0.9456
cytidine	1.1191	0.9591	0.5876
cytosine	0.9430	1.1401	0.5412
decadienedioic acid (C10:2-DC)**	0.9183	1.0894	0.9487
decanoylcarnitine (C10)	0.9770	0.9606	1.3370
dehydroepiandrosterone sulfate (DHEA-S)	0.9256	1.0373	1.1939
deoxycarnitine	0.9687	0.9852	1.2473
deoxycholate	1.0550	1.0675	0.3391
deoxycholic acid (12 or 24)-sulfate*	1.0154	1.1226	0.2504
deoxycholic acid glucuronide	1.0269	0.9896	0.9130
desmethylcitalopram*	1.0182	0.9860	0.9792
desmethylnaproxen	1.0000	1.0000	1.0000
desmethylnaproxen sulfate	1.0000	1.0000	1.0000
dexlansoprazole	1.1238	0.9998	0.3407
diacylglycerol (14:0/18:1, 16:0/16:1) [1]*	1.1801	0.9198	0.4760
diacylglycerol (14:0/18:1, 16:0/16:1) [2]*	1.1598	0.9383	0.4837
diacylglycerol (16:1/18:2 [2], 16:0/18:3 [1])*	1.0911	0.9511	0.7806
didesmethylcitalopram*	1.0572	0.9526	0.9526
dihomo-linoleate (20:2n6)	1.0424	0.9867	0.8459
dihomo-linolenate (20:3n3 or n6)	1.0360	1.0022	0.7959
dihomo-linolenoylcarnitine (C20:3n3 or 6)*	0.9650	0.9881	1.2516
dihomo-linolenoyl-choline	1.0517	0.9748	0.8619
dihomo-linoleoylcarnitine (C20:2)*	0.9453	0.9578	1.5217
dihydrocaffeate sulfate (2)	0.8632	1.0608	1.3987
dihydroferulic acid sulfate	0.9701	1.0611	0.8269
dihydroorotate	1.0639	1.0302	0.4947
dimethylarginine (SDMA + ADMA)	0.9925	0.9900	1.0946
dimethylglycine	0.9936	1.0227	0.9105
dimethylguanidino valeric acid (DMGV)*	1.2126	0.9230	0.2855
dimethyl sulfone	0.7389	1.3318	0.5859
docosadienoate (22:2n6)	0.9972	0.9993	1.0190
docosadioate (C22-DC)	0.8895	1.0932	1.0818
docosahexaenoate (DHA; 22:6n3)	1.0106	0.9827	1.0379
docosahexaenoylcholine	1.0002	0.9675	1.1759
docosapentaenoate (n3 DPA; 22:5n3)	1.0186	1.0159	0.8143
docosapentaenoate (n6 DPA; 22:5n6)	1.0270	1.0082	0.8109
docosapentaenoylcarnitine (C22:5n3)*	0.9549	0.9668	1.4212
docosatrienoate (22:3n3)	1.0366	1.0282	0.6512
docosatrienoate (22:3n6)*	1.1340	0.9437	0.5918
dodecadienoate (12:2)*	0.9698	1.0100	1.1070
dodecanedioate (C12-DC)	1.0641	0.9499	0.9308
dodecenedioate (C12:1-DC)*	1.0975	0.9052	0.9963
dopamine 3-O-sulfate	1.2210	0.8339	0.7257
dopamine 4-sulfate	1.2496	0.8091	0.7081
ectoine	0.7776	1.1703	1.2590
EDTA	0.9714	1.0016	1.1436
eicosanedioate (C20-DC)	0.9191	1.0238	1.3017
eicosapentaenoate (EPA; 20:5n3)	1.0242	0.9975	0.8846
eicosapentaenoylcholine	1.1367	0.8879	0.8811
eicosenedioate (C20:1-DC)*	0.9455	1.0201	1.1813
eicosenoate (20:1)	1.0101	0.9972	0.9617
eicosenoylcarnitine (C20:1)*	0.9088	0.9823	1.5829
enalapril	0.3886	1.7185	0.3491
enalaprilat*	0.7951	1.2424	0.7735
epiandrosterone sulfate	0.9941	0.9483	1.3127
ergothioneine	0.9159	1.0406	1.2277
erucate (22:1n9)	1.0618	0.9222	1.0940
erythritol	0.9425	1.0865	0.8355
erythronate*	1.0236	1.0184	0.7741
escitalopram	1.0082	0.9935	0.9918
ethyl alpha-glucopyranoside	1.0907	0.9287	0.9046
ethyl glucuronide	1.6886	0.4741	0.1906
ethylmalonate	0.9631	0.9817	1.2962
etiocholanolone glucuronide	0.8744	1.0138	1.5948
eugenol sulfate	1.2057	0.8554	0.6902
febuxostat	0.4204	1.6742	0.4204
ferulic acid 4-sulfate	1.0960	1.0504	0.2140
fexofenadine	0.9174	1.1795	0.4634
Fibrinopeptide A, des-ala(1)*	1.8542	0.2962	0.2761
flavin adenine dinucleotide (FAD)	0.9600	1.0488	0.9479
fluoxetine	1.0000	1.0000	1.0000
formiminoglutamate	0.9540	1.1199	0.5927
fructose	0.9879	1.0484	0.8009
fructosyllysine	1.0510	0.9981	0.7379
fumarate	1.0678	1.0001	0.6379
furosemide	1.2423	0.8400	0.5791
galactonate	1.2314	0.8668	0.4908
gamma-CEHC	1.0028	0.9774	1.1083
gamma-CEHC glucuronide*	1.0928	0.9811	0.6078
gamma-glutamyl-2-aminobutyrate	0.9997	1.0060	0.9691
gamma-glutamylalanine	1.1345	0.9773	0.4061
gamma-glutamyl-alpha-lysine	0.9830	1.0065	1.0556
gamma-glutamylcitrulline*	0.9455	0.9491	1.5679
gamma-glutamyl-epsilon-lysine	0.9871	1.0123	1.0017
gamma-glutamylglutamate	0.9910	1.0342	0.8621
gamma-glutamylglutamine	1.0090	0.9737	1.0954
gamma-glutamylglycine	0.9894	0.9848	1.1394
gamma-glutamylhistidine	1.0442	0.9871	0.8345
gamma-glutamylisoleucine*	1.0309	1.0058	0.8038
gamma-glutamylleucine	1.0344	0.9971	0.8324
gamma-glutamylmethionine	0.9878	1.0012	1.0585
gamma-glutamylphenylalanine	1.0063	1.0059	0.9341
gamma-glutamylthreonine	0.9823	0.9920	1.1381
gamma-glutamyltryptophan	0.9909	1.0196	0.9419
gamma-glutamyltyrosine	1.0355	0.9759	0.9420
gamma-glutamylvaline	1.0313	1.0022	0.8207
gamma-tocopherol/beta-tocopherol	0.9789	0.9693	1.2799
gentisate	1.0996	0.9453	0.7664
gluconate	1.0408	1.0111	0.7220
glucose	1.0507	0.9915	0.7761
glucuronate	1.0292	1.0096	0.7920
glucuronide of C10H18O2 (7)*	1.5102	0.6527	0.1694
glucuronide of C10H18O2 (8)*	1.4205	0.7176	0.2946
glucuronide of piperine metabolite C17H21NO3 (3)*	0.8546	1.1630	0.8883
glucuronide of piperine metabolite C17H21NO3 (4)*	0.8569	1.1892	0.7330
glucuronide of piperine metabolite C17H21NO3 (5)*	0.9471	1.0530	0.9935
glutamate	1.0400	1.0107	0.7281
glutamine	0.9960	0.9808	1.1256
glutamine conjugate of C6H10O2 (1)*	1.1755	0.8805	0.7144
glutamine conjugate of C6H10O2 (2)*	1.2539	0.8174	0.6398
glutamine conjugate of C7H12O2*	1.2167	0.8357	0.7389
glutarate (C5-DC)	1.3619	0.7389	0.4919
glutarylcarnitine (C5-DC)	0.9640	0.9938	1.2257
glycerate	0.9684	1.0154	1.0848
glycerol	1.0013	1.0741	0.5897
glycerol 3-phosphate	1.1240	0.9698	0.5029
glycerophosphoethanolamine	1.0841	0.9492	0.8285
glycerophosphoinositol*	1.2500	0.8693	0.3786
glycerophosphorylcholine (GPC)	0.7776	1.1041	1.6193
glycerophosphoserine*	1.2274	0.8460	0.6256
glycine	0.9785	1.0034	1.0962
glycine conjugate of C10H12O2*	0.9952	1.0284	0.8708
glycine conjugate of C10H14O2 (1)*	0.9663	1.0321	1.0052
glyco-beta-muricholate**	0.9171	1.1718	0.5065
glycochenodeoxycholate	1.0441	1.0540	0.4705
glycochenodeoxycholate 3-sulfate	1.0107	1.0376	0.7382
glycochenodeoxycholate glucuronide (1)	0.9594	1.0989	0.6780
glycocholate	1.2598	0.8499	0.4317
glycocholenate sulfate*	0.9599	0.9744	1.3530
glycodeoxycholate	1.0093	1.1358	0.2109
glycodeoxycholate 3-sulfate	0.9058	1.2059	0.3814
glycolithocholate	1.0837	1.0628	0.2116
glycolithocholate sulfate*	0.9857	1.1048	0.5058
glycosyl ceramide (d16:1/24:1, d18:1/22:1)*	0.9587	0.9994	1.2236
glycosyl ceramide (d18:1/20:0, d16:1/22:0)*	0.9288	0.9765	1.5074
glycosyl ceramide (d18:1/23:1, d17:1/24:1)*	0.9096	1.0070	1.4439
glycosyl ceramide (d18:2/24:1, d18:1/24:2)*	0.9338	0.9503	1.6236
glycosyl-N-(2-hydroxynervonoyl)-sphingosine (d18:1/24:1(2OH))*	0.8973	1.1104	0.9469
glycosyl-N-behenoyl-sphingadienine (d18:2/22:0)*	0.8805	0.9665	1.8197
glycosyl-N-palmitoyl-sphingosine (d18:1/16:0)	0.9878	0.9494	1.3408
glycosyl-N-stearoyl-sphingosine (d18:1/18:0)	0.9481	0.9960	1.2986
glycosyl-N-tricosanoyl-sphingadienine (d18:2/23:0)*	0.8197	1.0158	1.8753
glycoursodeoxycholate	1.2018	0.9181	0.3697
glycoursodeoxycholic acid sulfate (1)	1.3338	0.7985	0.3170
glycyrrhetinate	0.7660	1.1614	1.3694
guaiacol sulfate	1.0461	0.9809	0.8582
guanidinoacetate	0.9348	0.9915	1.3940
guanidinosuccinate	0.8064	1.1882	1.0080
guanine	0.5422	0.3573	6.9408
gulonate*	1.0746	0.9881	0.6671
heme	1.0087	0.8282	1.8887
heneicosapentaenoate (21:5n3)	1.0419	1.0106	0.7188
heptanoate (7:0)	1.0184	0.9895	0.9591
heptenedioate (C7:1-DC)*	0.9802	1.0356	0.9118
hexadecadienoate (16:2n6)	1.0280	1.0030	0.8340
hexadecanedioate (C16-DC)	1.0407	0.9634	0.9821
hexadecasphingosine (d16:1)*	0.9578	1.0259	1.0843
hexadecenedioate (C16:1-DC)*	1.0242	0.9813	0.9730
hexanoylcarnitine (C6)	0.9988	0.9992	1.0109
hexanoylglutamine	1.1070	0.9397	0.7574
hexanoylglycine	1.0118	0.9574	1.1687
hippurate	0.9919	0.8992	1.5921
histidine	0.9809	0.9996	1.1044
histidine betaine (hercynine)*	0.9009	1.0105	1.4717
homoarginine	0.9448	1.0294	1.1339
homocitrulline	0.9735	1.0900	0.6517
homostachydrine*	0.9436	1.0905	0.8078
homovanillate (HVA)	0.9105	1.0577	1.1633
hydantoin-5-propionate	1.0052	1.0748	0.5650
hydrochlorothiazide	0.8298	1.3032	0.2573
hydroquinone sulfate	0.9676	1.0759	0.7595
hydroxyasparagine**	1.0049	1.0149	0.8926
hydroxy-CMPF*	0.8381	1.0074	1.8232
hydroxycotinine	1.0955	1.0287	0.3341
hydroxy-N6,N6,N6-trimethyllysine*	0.9747	1.0345	0.9473
hydroxypalmitoyl sphingomyelin (d18:1/16:0(OH))**	0.9545	0.9628	1.4454
hyocholate	0.8979	1.0437	1.3066
hypotaurine	1.0268	0.9634	1.0566
hypoxanthine	0.9997	1.0263	0.8583
ibuprofen	1.0215	1.0084	0.8397
ibuprofen acyl glucuronide	0.9563	1.0741	0.8293
imidazole lactate	0.9727	1.0093	1.0954
imidazole propionate	1.0826	1.0055	0.5297
iminodiacetate (IDA)	0.9852	0.9995	1.0816
indole-3-carboxylate	1.0021	1.0032	0.9709
indoleacetate	1.0547	0.8972	1.2677
indoleacetoylcarnitine*	1.1633	0.7626	1.4217
indoleacetylglutamine	1.1606	0.8574	0.9196
indolebutyrate	1.1089	0.9094	0.9128
indolelactate	0.9529	1.0430	1.0173
indolepropionate	1.0825	0.8857	1.1824
indolin-2-one	1.0088	1.0133	0.8810
inosine	1.0804	1.0120	0.5059
inosine 5^-monophosphate (IMP)	1.0011	0.9949	1.0222
isobutyrylcarnitine (C4)	0.9863	0.9781	1.1921
isobutyrylglycine	0.9873	0.9794	1.1801
isocitrate	0.9427	1.0783	0.8793
isocitric lactone	1.1037	1.0137	0.3724
isoleucine	1.0189	1.0010	0.8936
isoleucylglycine	0.9209	0.9935	1.4570
isoursodeoxycholate	1.2043	0.9347	0.2659
isoursodeoxycholate sulfate (1)	1.3399	0.8132	0.2042
isovalerate (i5:0)	1.0306	0.9503	1.1074
isovalerylcarnitine (C5)	0.9538	1.0145	1.1670
kynurenate	0.9702	1.0390	0.9468
kynurenine	0.9814	1.0213	0.9831
lactate	1.0318	1.0286	0.6746
lactosyl-N-behenoyl-sphingosine (d18:1/22:0)*	0.9216	0.9630	1.6198
lactosyl-N-nervonoyl-sphingosine (d18:1/24:1)*	0.9509	0.9483	1.5433
lactosyl-N-palmitoyl-sphingosine (d18:1/16:0)	0.9697	0.9484	1.4427
lanthionine	1.1005	0.9784	0.5815
laurate (12:0)	0.9535	1.0655	0.8917
laurylcarnitine (C12)	0.9454	0.9679	1.4662
leucine	1.0131	0.9999	0.9308
leucylalanine	0.9707	1.0185	1.0552
leucylglycine	0.9590	0.9800	1.3276
lignoceroylcarnitine (C24)*	0.8829	1.0360	1.4289
lignoceroyl sphingomyelin (d18:1/24:0)	0.9505	0.9781	1.3834
linoleate (18:2n6)	1.0472	0.9720	0.9004
linolenate [alpha or gamma; (18:3n3 or 6)]	1.0489	0.9902	0.7924
linolenoylcarnitine (C18:3)*	0.9685	0.9332	1.5319
linoleoyl-arachidonoyl-glycerol (18:2/20:4) [1]*	1.0955	0.9692	0.6581
linoleoyl-arachidonoyl-glycerol (18:2/20:4) [2]*	1.1062	0.9568	0.6686
linoleoylcarnitine (C18:2)*	0.9472	0.9598	1.5003
linoleoylcholine*	1.0264	0.9120	1.3382
linoleoyl-docosahexaenoyl-glycerol (18:2/22:6) [1]*	1.0333	0.9902	0.8758
linoleoyl ethanolamide	1.0438	0.9331	1.1304
linoleoyl-linolenoyl-glycerol (18:2/18:3) [1]*	1.0561	0.9363	1.0477
linoleoyl-linolenoyl-glycerol (18:2/18:3) [2]*	1.1823	0.8704	0.7336
linoleoyl-linoleoyl-glycerol (18:2/18:2) [1]*	1.0607	0.9182	1.1213
linoleoyl-linoleoyl-glycerol (18:2/18:2) [2]*	1.0433	0.9491	1.0464
lithocholate sulfate (1)	1.0340	1.0867	0.3466
lithocholic acid sulfate (2)	0.8847	1.1808	0.6306
L-urobilin	0.5986	1.4615	0.6285
lysine	0.9842	1.0038	1.0635
malate	1.0380	1.0064	0.7622
maleate	0.8500	1.2751	0.3020
malonate	0.9809	1.0261	0.9595
malonylcarnitine	1.0153	0.9812	1.0204
maltose	0.9254	0.9855	1.4765
maltotriose	0.8924	1.0144	1.4954
mannitol/sorbitol	1.0821	0.9389	0.8945
mannonate*	1.0649	0.9998	0.6549
mannose	1.0607	0.9909	0.7262
margarate (17:0)	1.0414	0.9834	0.8699
margaroylcarnitine (C17)*	0.8980	1.0225	1.4212
metabolonic lactone sulfate	1.0805	0.9507	0.8390
metformin	1.0704	1.1147	0.0002
methionine	0.9799	1.0063	1.0731
methionine sulfone	0.9626	1.0639	0.8515
methionine sulfoxide	1.0260	1.0017	0.8520
methyl-4-hydroxybenzoate sulfate	0.8907	1.2276	0.3438
methyl glucopyranoside (alpha + beta)	0.8338	1.0591	1.5645
methyl indole-3-acetate	1.0735	0.9345	0.9646
methylmalonate (MMA)	1.1635	0.8842	0.7587
methylsuccinate	1.0328	0.9878	0.8915
metoprolol	1.4813	0.6380	0.4038
metoprolol acid metabolite*	1.4756	0.7070	0.0589
myo-inositol	1.0237	0.9777	0.9953
myristate (14:0)	1.0389	1.0055	0.7625
myristoleate (14:1n5)	1.0101	1.0189	0.8435
myristoleoylcarnitine (C14:1)*	0.9609	0.9543	1.4578
myristoylcarnitine (C14)	0.9580	0.9822	1.3209
myristoyl dihydrosphingomyelin (d18:0/14:0)*	0.9350	0.9969	1.3636
myristoyl-linoleoyl-glycerol (14:0/18:2) [1]*	1.0665	1.0169	0.5536
myristoyl-linoleoyl-glycerol (14:0/18:2) [2]*	1.0910	0.9911	0.5632
N1-Methyl-2-pyridone-5-carboxamide	0.9736	1.0622	0.8025
N1-methyladenosine	1.0079	1.0011	0.9519
N1-methylinosine	0.9976	1.0126	0.9444
(N(1) + N(8))-acetylspermidine	1.0690	0.9243	1.0444
N2-acetyl,N6-methyllysine	1.0200	0.9651	1.0833
N2-acetyl,N6,N6-dimethyllysine	1.0584	0.9468	0.9779
N-(2-furoyl)glycine	0.9588	1.1893	0.1887
N2-methylguanosine	0.9725	1.0197	1.0395
N2,N2-dimethylguanosine	1.0300	0.9794	0.9525
N2,N5-diacetylornithine	0.9636	1.0076	1.1528
N4-acetylcytidine	1.0082	1.0209	0.8423
N6-acetyllysine	0.9991	1.0060	0.9717
N6-carbamoylthreonyladenosine	1.0039	0.9972	0.9940
N6-carboxymethyllysine	0.9733	1.0996	0.6003
N6-methyllysine	1.0280	1.0005	0.8477
N6,N6-dimethyllysine	1.0180	0.9733	1.0492
N6,N6,N6-trimethyllysine	0.9005	1.0532	1.2411
N6-succinyladenosine	1.0002	1.0340	0.8143
N-acetyl-1-methylhistidine*	0.8355	1.1388	1.1221
N-acetyl-2-aminooctanoate*	0.9289	1.0028	1.3642
N-acetyl-3-methylhistidine*	0.6348	1.3983	0.7791
N-acetylalanine	1.0106	0.9988	0.9500
N-acetylalliin	0.8771	0.9994	1.6585
N-acetylarginine	0.9871	0.9802	1.1763
N-acetylaspartate (NAA)	1.0109	1.0024	0.9289
N-acetyl-aspartyl-glutamate (NAAG)	0.8911	1.1121	0.9704
N-acetyl-beta-alanine	1.0873	0.9156	0.9937
N-acetylcarnosine	0.9448	1.0572	0.9830
N-acetylcitrulline	0.9490	1.0784	0.8448
N-acetylglucosamine/N-acetylgalactosamine	1.0518	1.0012	0.7172
N-acetylglucosaminylasparagine	0.9608	1.0495	0.9394
N-acetylglutamate	1.0599	0.9971	0.6963
N-acetylglutamine	0.9819	1.0079	1.0539
N-acetylglycine	1.0376	0.9113	1.2826
N-acetylhistidine	1.0476	0.9387	1.0801
N-acetyl-isoputreanine	1.0436	0.9714	0.9229
N-acetylleucine	1.0859	0.9453	0.8392
N-acetylmethionine	1.0272	0.9629	1.0573
N-acetylneuraminate	0.9821	1.0155	1.0112
N-acetylphenylalanine	1.0251	0.9930	0.9043
N-acetylproline	1.0684	0.9497	0.9087
N-acetylputrescine	1.0627	0.9605	0.8807
N-acetylserine	1.0253	0.9834	0.9553
N-acetyl sulfapyridine	1.0000	1.0000	1.0000
N-acetyltaurine	1.0698	0.9801	0.7358
N-acetylthreonine	1.0061	0.9966	0.9860
N-acetyltryptophan	0.9503	1.0518	0.9831
N-acetyltyrosine	1.0135	0.9855	1.0069
N-acetylvaline	1.0351	0.9681	0.9863
naproxen	1.0000	1.0000	1.0000
N-behenoyl-sphingadienine (d18:2/22:0)*	0.9087	0.9922	1.5294
N-carbamoylalanine	1.0235	1.0151	0.7928
N-carbamoylaspartate	0.9958	1.0036	1.0030
N-carbamoylvaline	1.0177	0.9871	0.9755
N-delta-acetylornithine	0.9327	1.0649	1.0054
N-desmethyl tramadol	0.6326	1.4274	0.6326
nervonate (24:1n9)*	1.0375	0.9066	1.3085
nervonoylcarnitine (C24:1)*	0.9160	1.0597	1.1232
N-formylanthranilic acid	0.9582	1.0724	0.8284
N-formylmethionine	1.0181	0.9888	0.9646
N-formylphenylalanine	0.9652	1.0717	0.7953
nicotinamide	0.9800	0.9756	1.2395
nisinate (24:6n3)	1.0810	0.9938	0.6016
N-methylhydroxyproline**	1.1295	0.9362	0.6567
N-methylpipecolate	0.9500	1.0920	0.7659
N-methylproline	1.1142	0.9511	0.6570
N-methyltaurine	0.7277	1.3187	0.7169
N,N-dimethyl-5-aminovalerate	1.1886	0.9355	0.3451
N,N-dimethylalanine	0.8673	1.0341	1.5219
N,N,N-trimethyl-5-aminovalerate	0.9567	1.0964	0.7064
N,N,N-trimethyl-alanylproline betaine (TMAP)	0.9386	1.0310	1.1585
N,O-didesmethylvenlafaxine glucuronide	1.0000	1.0000	1.0000
N-oleoylserine	0.9599	0.9714	1.3694
N-oleoyltaurine	1.0478	0.9148	1.2093
nonadecanoate (19:0)	0.9878	0.9968	1.0825
nonanoylcarnitine (C9)	1.0309	0.9173	1.2852
norcotinine	0.9961	1.0218	0.9021
norfluoxetine	1.0000	1.0000	1.0000
N-oxalyl glycine (NOG)	0.9452	1.0574	0.9800
N-palmitoylglycine	0.9924	0.9744	1.1800
N-palmitoyl-heptadecasphingosine (d17:1/16:0)*	0.9979	0.9670	1.1910
N-palmitoyl-sphingadienine (d18:2/16:0)*	0.9914	0.9583	1.2734
N-palmitoyl-sphinganine (d18:0/16:0)	1.0746	0.9479	0.8853
N-palmitoyl-sphingosine (d18:1/16:0)	1.0281	0.9529	1.1068
N-stearoyl-sphingadienine (d18:2/18:0)*	1.0022	0.9823	1.0842
N-stearoyl-sphinganine (d18:0/18:0)*	1.0647	0.9963	0.6753
N-stearoyl-sphingosine (d18:1/18:0)*	1.0121	0.9844	1.0202
N-stearoyltaurine	1.0222	0.9764	1.0100
o-cresol sulfate	1.1508	0.9796	0.3067
octadecadienedioate (C18:2-DC)*	1.2721	0.7493	0.9138
octadecanedioate (C18-DC)	1.0030	0.9847	1.0672
octadecanedioylcarnitine (C18-DC)*	0.9683	0.9768	1.2952
octadecenedioate (C18:1-DC)*	1.0453	0.9671	0.9376
octadecenedioylcarnitine (C18:1-DC)*	0.9994	0.9461	1.2971
octanoylcarnitine (C8)	1.0121	0.9387	1.2687
O-desmethyltramadol	0.7994	1.2333	0.7994
O-desmethyltramadol glucuronide	0.7844	1.2508	0.7844
O-desmethylvenlafaxine	1.0000	1.0000	1.0000
oleate/vaccenate (18:1)	1.0369	0.9853	0.8835
oleoyl-arachidonoyl-glycerol (18:1/20:4) [1]*	1.0707	0.9874	0.6918
oleoyl-arachidonoyl-glycerol (18:1/20:4) [2]*	1.0909	0.9777	0.6366
oleoylcarnitine (C18:1)	0.9421	0.9841	1.3956
oleoylcholine	1.0055	0.9644	1.1643
oleoyl ethanolamide	1.0310	0.9518	1.0970
oleoyl-linolenoyl-glycerol (18:1/18:3) [2]*	1.0648	0.9337	1.0151
oleoyl-linoleoyl-glycerol (18:1/18:2) [1]	1.0583	0.9433	0.9983
oleoyl-linoleoyl-glycerol (18:1/18:2) [2]	1.0851	0.9267	0.9455
oleoyl-oleoyl-glycerol (18:1/18:1) [1]*	1.0778	0.9484	0.8658
oleoyl-oleoyl-glycerol (18:1/18:1) [2]*	1.0910	0.9389	0.8472
omeprazole	0.7106	1.3758	0.4970
ornithine	0.9787	0.9994	1.1167
orotate	1.0606	0.9711	0.8343
orotidine	1.2059	0.8931	0.4838
O-sulfo-L-tyrosine	0.9683	1.0274	1.0200
oxalate (ethanedioate)	0.9768	1.0053	1.0953
oxypurinol	0.9981	1.0022	0.9981
palmitate (16:0)	1.0328	0.9939	0.8582
palmitoleate (16:1n7)	1.0987	0.9610	0.6860
palmitoleoyl-arachidonoyl-glycerol (16:1/20:4) [2]*	1.0856	0.9847	0.6268
palmitoleoylcarnitine (C16:1)*	0.9799	0.9661	1.2919
palmitoleoyl-linoleoyl-glycerol (16:1/18:2) [1]*	1.0998	0.9414	0.7864
palmitoleoyl-oleoyl-glycerol (16:1/18:1) [1]*	1.0982	0.9535	0.7296
palmitoleoyl-oleoyl-glycerol (16:1/18:1) [2]*	1.0662	0.9919	0.6909
palmitoyl-arachidonoyl-glycerol (16:0/20:4) [1]*	1.1099	0.9569	0.6483
palmitoyl-arachidonoyl-glycerol (16:0/20:4) [2]*	1.1460	0.9699	0.3852
palmitoylcarnitine (C16)	0.9411	1.0089	1.2657
palmitoylcholine	1.0446	0.9366	1.1070
palmitoyl dihydrosphingomyelin (d18:0/16:0)*	0.9526	0.9810	1.3560
palmitoyl-docosahexaenoyl-glycerol (16:0/22:6) [1]*	1.1377	0.9326	0.6323
palmitoyl-linoleoyl-glycerol (16:0/18:2) [1]*	1.0315	1.0029	0.8157
palmitoyl-linoleoyl-glycerol (16:0/18:2) [2]*	1.1144	0.9352	0.7428
palmitoyl-oleoyl-glycerol (16:0/18:1) [1]*	1.1296	0.9364	0.6550
palmitoyl-oleoyl-glycerol (16:0/18:1) [2]*	1.1370	0.9250	0.6776
palmitoyl sphingomyelin (d18:1/16:0)	0.9730	0.9838	1.2319
palmitoyl-sphingosine-phosphoethanolamine (d18:1/16:0)	0.9796	0.9751	1.2444
pantoate	0.9311	1.1480	0.5614
pantoprazole	0.3631	1.7534	0.2946
pantothenate	1.0055	1.0570	0.6604
paraxanthine	0.9590	1.0806	0.7798
p-cresol glucuronide*	1.0699	0.9675	0.8041
p-cresol sulfate	0.9660	1.0340	0.9958
pentadecanoate (15:0)	1.0326	0.9909	0.8757
pentose acid*	1.1344	0.8736	0.9717
perfluorooctanesulfonate (PFOS)	0.9108	1.0435	1.2388
perfluorooctanoate (PFOA)	0.8044	1.0811	1.6015
phenol sulfate	0.8945	1.1685	0.6450
phenylacetate	0.9616	1.0614	0.8706
phenylacetylcarnitine	1.0810	0.9226	0.9896
phenylacetylglutamate	0.8878	1.1283	0.8998
phenylacetylglutamine	0.9976	1.0210	0.8986
phenylacetylglycine	1.1627	0.9542	0.3821
phenylalanine	0.9919	1.0100	0.9885
phenyllactate (PLA)	0.9936	1.0124	0.9665
phenylpyruvate	0.9720	1.0381	0.9419
phosphate	1.0191	0.9819	0.9969
phosphoethanolamine	0.9667	1.0254	1.0394
picolinate	0.9993	1.0369	0.8033
picolinoylglycine	1.0018	1.0500	0.7182
pimeloylcarnitine/3-methyladipoylcarnitine (C7-DC)	0.9013	0.9841	1.6126
pipecolate	1.1148	0.8781	1.0518
piperine	0.8152	1.2257	0.7567
pregabalin	1.0007	1.0089	0.9477
pregnanediol-3-glucuronide	0.9099	1.0257	1.3405
pregnenediol disulfate (C21H34O8S2)*	0.8513	1.1389	1.0369
pregnenediol sulfate (C21H34O5S)*	0.8693	1.0705	1.3131
pregnenetriol disulfate*	0.9178	1.0793	1.0070
pregnenetriol sulfate*	0.8944	1.0587	1.2434
pregnenolone sulfate	0.9016	1.0599	1.1987
pro-hydroxy-pro	1.0458	0.9449	1.0558
proline	1.0293	1.0056	0.8130
prolylglycine	1.0688	0.9426	0.9455
propionylcarnitine (C3)	0.9842	1.0291	0.9258
propionylglycine	1.0179	1.0141	0.8278
propyl 4-hydroxybenzoate sulfate	0.8348	1.2480	0.5305
pseudouridine	1.0053	1.0005	0.9687
pyridoxate	1.1393	0.9157	0.7160
pyroglutamine*	1.0455	0.9332	1.1211
pyrraline	0.9907	1.0495	0.7803
pyruvate	1.0154	1.0332	0.7370
quinate	1.0190	1.0007	0.8952
quinine	0.3739	1.7497	0.2574
quinolinate	0.9935	0.9887	1.0964
(R)-3-hydroxybutyrylcarnitine	1.1996	0.8625	0.6842
retinal	1.0212	0.9767	1.0137
retinol (Vitamin A)	0.9450	1.0563	0.9871
ribitol	1.0648	0.9708	0.8131
ribonate	1.0328	1.0083	0.7800
ribulonate/xylulonate/lyxonate*	0.9837	1.0252	0.9497
S-1-pyrroline-5-carboxylate	0.9483	1.0203	1.1652
(S)-3-hydroxybutyrylcarnitine	1.0743	0.9573	0.8363
saccharin	0.7651	1.3964	0.0947
S-adenosylhomocysteine (SAH)	0.9840	1.0007	1.0815
salicylate	1.2820	0.9034	0.0216
salicyluric glucuronide*	1.1592	1.0221	0.0305
sarcosine	0.9944	0.9890	1.0894
sebacate (C10-DC)	1.0643	0.9674	0.8348
sedoheptulose	1.0733	0.9435	0.9167
serine	0.9688	1.0134	1.0936
serotonin	0.9450	1.0415	1.0676
sitagliptin	1.0098	1.1481	0.1412
S-methylcysteine	1.0365	0.9758	0.9372
S-methylcysteine sulfoxide	1.0460	0.9914	0.8013
spermidine	0.9864	0.9941	1.1048
sphingadienine	0.9550	0.9981	1.2507
sphinganine	0.9806	0.9880	1.1692
sphinganine-1-phosphate	0.9956	1.0063	0.9892
sphingomyelin (d17:1/14:0, d16:1/15:0)*	0.9101	0.9939	1.5126
sphingomyelin (d17:1/16:0, d18:1/15:0, d16:1/17:0)*	0.9409	0.9939	1.3482
sphingomyelin (d17:2/16:0, d18:2/15:0)*	0.8889	1.0344	1.4052
sphingomyelin (d18:0/18:0, d19:0/17:0)*	0.9616	1.0811	0.7632
sphingomyelin (d18:0/20:0, d16:0/22:0)*	0.9460	1.0728	0.8918
sphingomyelin (d18:1/14:0, d16:1/16:0)*	0.9606	0.9965	1.2294
sphingomyelin (d18:1/17:0, d17:1/18:0, d19:1/16:0)	0.9274	1.0272	1.2393
sphingomyelin (d18:1/18:1, d18:2/18:0)	0.9507	1.0340	1.0778
sphingomyelin (d18:1/19:0, d19:1/18:0)*	0.9267	1.0423	1.1607
sphingomyelin (d18:1/20:0, d16:1/22:0)*	0.9519	1.0187	1.1544
sphingomyelin (d18:1/20:1, d18:2/20:0)*	0.9396	1.0372	1.1196
sphingomyelin (d18:1/20:2, d18:2/20:1, d16:1/22:2)*	0.9249	1.0648	1.0474
sphingomyelin (d18:1/21:0, d17:1/22:0, d16:1/23:0)*	0.9242	1.0233	1.2769
sphingomyelin (d18:1/22:1, d18:2/22:0, d16:1/24:1)*	0.9343	1.0110	1.2905
sphingomyelin (d18:1/22:2, d18:2/22:1, d16:1/24:2)*	0.9479	1.0266	1.1327
sphingomyelin (d18:1/24:1, d18:2/24:0)*	0.9591	0.9959	1.2405
sphingomyelin (d18:1/25:0, d19:0/24:1, d20:1/23:0, d19:1/24:0)*	0.9634	1.0009	1.1900
sphingomyelin (d18:2/14:0, d18:1/14:1)*	0.9124	1.0198	1.3591
sphingomyelin (d18:2/16:0, d18:1/16:1)*	0.9402	1.0033	1.3009
sphingomyelin (d18:2/18:1)*	0.9380	1.0082	1.2860
sphingomyelin (d18:2/21:0, d16:2/23:0)*	0.8926	1.0472	1.3161
sphingomyelin (d18:2/23:0, d18:1/23:1, d17:1/24:1)*	0.9074	1.0131	1.4225
sphingomyelin (d18:2/23:1)*	0.8992	1.0207	1.4251
sphingomyelin (d18:2/24:1, d18:1/24:2)*	0.9335	1.0020	1.3441
sphingomyelin (d18:2/24:2)*	0.9382	1.0001	1.3287
sphingosine	1.0049	0.9870	1.0446
sphingosine 1-phosphate	0.9880	1.0031	1.0468
stachydrine	1.0605	0.9902	0.7307
stearate (18:0)	1.0186	0.9872	0.9702
stearidonate (18:4n3)	1.0106	1.0372	0.7407
stearoyl-arachidonoyl-glycerol (18:0/20:4) [1]*	1.0461	0.9893	0.8124
stearoyl-arachidonoyl-glycerol (18:0/20:4) [2]*	1.0452	0.9543	1.0075
stearoylcarnitine (C18)	0.9061	0.9978	1.5126
stearoylcholine*	1.0105	0.9749	1.0805
stearoyl sphingomyelin (d18:1/18:0)	0.9753	1.0329	0.9523
suberate (C8-DC)	1.1024	0.9428	0.7652
succinate	1.0223	0.9859	0.9579
succinimide	0.9171	0.9382	1.7786
succinoyltaurine	1.0004	1.0401	0.7796
succinylcarnitine (C4-DC)	0.9888	1.0396	0.8443
sucrose	1.2301	0.8673	0.4950
sulfate*	0.9692	1.0332	0.9840
sulfate of piperine metabolite C16H19NO3 (2)*	0.7855	1.2408	0.8331
sulfate of piperine metabolite C16H19NO3 (3)*	0.7591	1.2640	0.8473
sulfate of piperine metabolite C18H21NO3 (1)*	0.7225	1.2730	0.9935
sulfate of piperine metabolite C18H21NO3 (3)*	0.7374	1.2655	0.9550
tartarate	1.8586	0.2712	0.3891
tartronate (hydroxymalonate)	0.9591	1.0185	1.1176
taurine	0.9640	1.0099	1.1382
taurochenodeoxycholate	1.1290	0.9882	0.3763
taurochenodeoxycholic acid 3-sulfate	0.9924	1.0080	0.9972
taurocholate	1.4016	0.7535	0.1999
taurocholenate sulfate*	0.9642	0.9394	1.5212
taurodeoxycholate	1.0035	1.1569	0.1272
taurodeoxycholic acid 3-sulfate	0.8546	1.2446	0.4437
taurolithocholate 3-sulfate	0.9199	1.1418	0.6547
tetradecadienedioate (C14:2-DC)*	1.0328	0.9581	1.0535
tetradecadienoate (14:2)*	0.9784	1.0078	1.0730
tetradecanedioate (C14-DC)	1.0709	0.9193	1.0611
tetrahydrocortisol sulfate (1)	1.0063	1.0604	0.6377
theobromine	1.0034	0.9382	1.3183
theophylline	0.9679	1.0475	0.9129
thioproline	0.9927	1.0283	0.8848
threonate	1.0068	1.0071	0.9252
threonine	0.9628	1.0062	1.1649
thymol sulfate	0.5488	1.3917	1.2737
thyroxine	0.9966	1.0055	0.9884
tiglylcarnitine (C5:1-DC)	0.9902	1.0240	0.9214
tramadol	0.6277	1.4331	0.6277
trans-4-hydroxyproline	1.0151	1.0159	0.8331
trans-urocanate	1.0123	0.9529	1.1911
tricosanoyl sphingomyelin (d18:1/23:0)*	0.9425	0.9932	1.3439
tridecenedioate (C13:1-DC)*	0.9922	0.9972	1.0570
trigonelline (N^-methylnicotinate)	0.9879	1.0523	0.7799
trimethylamine N-oxide	0.9550	1.0448	0.9963
tryptophan	0.9683	1.0243	1.0369
tryptophan betaine	0.6038	1.1730	2.1714
tyramine O-sulfate	0.9237	1.2026	0.3040
tyrosine	0.9806	1.0174	1.0091
umbelliferone sulfate	0.9182	1.2323	0.1711
undecanedioate (C11-DC)	0.9829	1.0117	1.0278
undecenoylcarnitine (C11:1)	0.9427	1.0093	1.2550
uracil	0.9861	0.9848	1.1572
urate	0.9473	1.0459	1.0314
urea	0.9140	1.0829	1.0071
uridine	0.9928	0.9777	1.1594
ursodeoxycholate	1.1412	0.9759	0.3781
valine	1.0099	1.0027	0.9322
valylglycine	0.9645	0.9702	1.3513
vanillactate	0.9849	1.0254	0.9425
vanillic acid glycine	1.0079	1.0232	0.8317
vanillylmandelate (VMA)	0.9201	1.0246	1.2924
venlafaxine	1.0000	1.0000	1.0000
verapamil	1.0000	1.0000	1.0000
warfarin	0.9639	1.2175	0.0083
xanthine	0.9347	1.0848	0.8868
xanthurenate	0.9227	1.1217	0.7499
ximenoylcarnitine (C26:1)*	0.8548	1.0517	1.4932
xylose	1.0397	1.0080	0.7451
zolpidem	0.9607	1.0457	0.9607

Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study

Factors:

F1	Group:Diabetic Neuropathy
F2	Group:Diabetic non neuropathy
F3	Group:Normal