Data for (Study ST002172)
(Analysis AN003559)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 |
|---|---|---|---|---|
| 1,3-Diaminopropane | NA | 0.9333 | NA | 1.2667 |
| 1-Amino-1-cyclopentanecarboxylate | NA | NA | NA | NA |
| 1-Aminocyclopropane-1-carboxylate | NA | NA | NA | NA |
| 1-Methyl-2-pyrrolidinone | NA | NA | NA | NA |
| 1-Methyladenosine | 1.0261 | 1.3993 | 0.4378 | 0.9963 |
| 1-Methylhistamine | 0.9466 | 0.6614 | 0.8432 | 1.4508 |
| 1-Methylnicotinamide | 1.2450 | 0.6026 | 0.6623 | 1.4901 |
| 2,3-Diaminopropionate | NA | NA | NA | NA |
| 2,4-Diaminobutyrate | NA | NA | NA | 1.0000 |
| 2,4-Dimethylaniline | NA | NA | NA | NA |
| 2AB | 0.1607 | 0.0797 | 2.6085 | 1.1511 |
| 2-Aminobenzimidazole | NA | NA | NA | NA |
| 2-Aminophenol | NA | NA | NA | 1.0000 |
| 2^-Deoxycytidine | 2.3426 | 1.4726 | 0.0455 | 0.1393 |
| 2^-Deoxyguanosine | 1.8701 | 1.3376 | 0.1482 | 0.2415 |
| 2^-Deoxyinosine | 1.2059 | 0.7941 | NA | NA |
| 2-Deoxystreptamine | NA | NA | NA | NA |
| 2-Guanidinobenzimidazole | 0.6237 | NA | 1.3763 | NA |
| 3,3^,5-Triiodothyronine | NA | NA | NA | NA |
| 3,5-Diiodo-tyrosine | NA | NA | NA | NA |
| 3-Aminoisobutyrate | NA | NA | NA | NA |
| 3-Aminopropane-1,2-diol | NA | NA | 0.9570 | 1.0430 |
| 3-Aminopropionitrile | NA | NA | NA | NA |
| 3-Chloroalanine | NA | NA | NA | NA |
| 3-Hydroxyanthranilate | NA | NA | NA | NA |
| 3-Hydroxykynurenine | NA | NA | NA | NA |
| 3-Iodotyrosine | NA | NA | NA | NA |
| 3-Methoxytyramine | NA | NA | NA | NA |
| 3-Methyladenine | NA | NA | NA | NA |
| 3-Methylguanine | NA | NA | NA | NA |
| 3-Methylhistidine | 0.2820 | 1.0430 | 0.2795 | 2.3955 |
| 4-Amino-3-hydroxybutyrate | NA | NA | 0.6471 | 1.1765 |
| 4-Aminosalicylate | NA | NA | NA | NA |
| 4-(beta-Acetylaminoethyl)imidazole | NA | NA | 0.3064 | 1.6936 |
| 4-Hydroxymethylimidazole | NA | NA | 1.1473 | 0.7790 |
| 4-Methyl-5-thiazoleethanol | NA | NA | 1.0000 | NA |
| 5,6-Dimethylbenzimidazole | NA | NA | NA | NA |
| 5-Aminolevulinate | 0.4953 | 0.4617 | 0.9066 | 2.1364 |
| 5-Aminovalerate | 0.2434 | 0.2356 | 2.5473 | 0.9736 |
| 5^-Deoxyadenosine | NA | NA | NA | NA |
| 5-Hydroxyindoleacetate | 0.0921 | 0.2850 | 0.0817 | 2.6281 |
| 5-Hydroxylysine | 0.4190 | 1.1798 | 0.7370 | 1.6642 |
| 5-Hydroxytryptophan | NA | NA | NA | NA |
| 5-Methoxyindoleacetate | NA | NA | NA | NA |
| 5-Methoxytryptamine | NA | NA | NA | NA |
| 5-Methyl-2^-deoxycytidine | 0.6794 | 1.3206 | NA | NA |
| 5-Methylcytosine | NA | NA | NA | NA |
| 5-Methyltetrahydrofolate | NA | NA | NA | 1.0000 |
| 5-Methylthioadenosine | 0.8978 | 0.2530 | 1.5370 | 1.3121 |
| 5-Oxoproline | 1.1466 | 1.5881 | 0.5751 | 0.6902 |
| 6-Aminohexanoate | 0.9517 | 0.2207 | 2.3557 | 0.4718 |
| 6-Hydroxynicotinate | NA | NA | NA | NA |
| 6-Methylaminopurine | NA | NA | NA | NA |
| 7,8-Dihydrobiopterin | 0.7446 | 0.5774 | 1.6460 | 1.0320 |
| 7,8-Dihydroneopterin | NA | NA | NA | NA |
| 7-Methylguanine | 0.7148 | 0.9485 | 0.9210 | 1.4158 |
| Acetylcholine | 0.1992 | 0.1497 | 3.1956 | 0.4556 |
| Adenine | NA | NA | 0.7392 | 1.2608 |
| Adenosine | 0.4061 | 1.5092 | 0.5632 | 1.5215 |
| ADMA | 0.3461 | 0.3728 | 1.1249 | 2.1561 |
| Agmatine | 0.1543 | 0.6679 | 0.5305 | 2.0130 |
| AICAR | NA | NA | NA | NA |
| Ala | 0.8762 | 0.6467 | 1.7445 | 0.7327 |
| Ala-Ala | 0.1032 | 0.1070 | 0.8491 | 2.9407 |
| Allantoin | 0.8672 | 0.7497 | 0.8338 | 1.5493 |
| Alliin | NA | NA | NA | NA |
| alpha-Aminoadipate | 0.4446 | 1.6133 | 0.5012 | 1.4409 |
| alpha-Methylbenzylamine | NA | NA | NA | NA |
| Alpha-Methylserine | NA | NA | 0.7317 | 1.2683 |
| Amantadine | NA | NA | NA | NA |
| Aniline | NA | NA | NA | NA |
| Anserine | 0.0852 | 2.0149 | 0.1014 | 1.7985 |
| Anthranilate | NA | NA | NA | 1.0000 |
| Arg | 1.6572 | 1.4585 | 0.7055 | 0.1789 |
| Arginine ethyl ester | NA | NA | NA | NA |
| Argininosuccinate | 0.8327 | 1.0855 | 0.9160 | 1.1658 |
| Asn | 2.2737 | 1.6452 | 0.0405 | 0.0407 |
| Asp | 1.4592 | 0.8809 | 0.7321 | 0.9278 |
| Benzamide | NA | NA | NA | NA |
| Benzamidine | NA | NA | NA | NA |
| Benzimidazole | NA | NA | NA | NA |
| beta-Ala | 0.2235 | 0.8212 | 1.1508 | 1.8045 |
| beta-Ala-Lys | NA | 1.0000 | NA | NA |
| beta-Cyanoalanine | NA | NA | NA | NA |
| beta-Imidazolelactate | NA | NA | NA | NA |
| Betaine | 0.4416 | 0.3811 | 1.4821 | 1.6952 |
| Betaine aldehyde | 1.6779 | 0.6794 | 0.8578 | 0.6691 |
| beta-Leucine | NA | NA | NA | NA |
| Betonicine | NA | NA | NA | NA |
| Bis(3-aminopropyl)amine | NA | NA | NA | NA |
| Cadaverine | 0.0048 | 0.0198 | 3.6044 | 0.3711 |
| Canavanine | NA | NA | NA | NA |
| Carnitine | 1.1929 | 0.9446 | 1.4457 | 0.4169 |
| Carnosine | 1.3234 | 0.7367 | NA | 0.4963 |
| Castanospermine | NA | NA | NA | 1.0000 |
| Choline | 0.8732 | 0.3693 | 2.2073 | 0.5502 |
| Citrulline | 0.2249 | 0.2841 | 2.5818 | 0.9092 |
| Creatine | 1.1655 | 0.4034 | 1.4544 | 0.9767 |
| Creatinine | 0.2060 | 1.7813 | 0.2539 | 1.7588 |
| Cyanocobalamin | NA | NA | NA | NA |
| Cyclohexylamine | NA | NA | NA | NA |
| Cys | NA | NA | NA | NA |
| Cys-Gly | NA | NA | NA | NA |
| Cystathionine | NA | NA | NA | NA |
| Cysteamine | NA | NA | NA | NA |
| Cysteine-glutathione disulphide | 1.7111 | 1.1145 | 0.1459 | 0.4687 |
| Cystine | 2.3582 | 1.0935 | 0.5210 | 0.0272 |
| Cytidine | 1.9005 | 1.5375 | 0.2726 | 0.2894 |
| Cytosine | NA | 1.0570 | 0.9070 | 1.0256 |
| Desthiobiotin | NA | NA | NA | NA |
| Diethanolamine | 0.4372 | 0.9108 | 1.0376 | 1.2095 |
| Dihydrouracil | NA | NA | NA | NA |
| DOPA | 0.1343 | 3.0767 | 0.1666 | 0.1977 |
| Dopamine | NA | NA | NA | 1.0000 |
| Ectoine | NA | NA | NA | NA |
| Epinephrine | NA | NA | NA | NA |
| Ethanolamine phosphate | NA | NA | NA | NA |
| GABA | 0.2612 | 0.9794 | 0.8083 | 1.7664 |
| gamma-Butyrobetaine | 0.0624 | 0.1098 | 1.4664 | 2.3613 |
| gamma-Glu-2AB | NA | NA | NA | NA |
| gamma-Glu-cys | NA | NA | NA | NA |
| gamma-Guanidinobutyrate | 1.0986 | 0.8704 | 0.3752 | 1.6557 |
| Gln | 1.6005 | 1.2609 | 0.4061 | 0.7326 |
| Glu | 1.8337 | 0.7868 | 0.6440 | 0.7354 |
| Glucosaminate | NA | 0.6773 | NA | 1.3227 |
| Glucosamine | 0.8378 | 2.2016 | 0.3244 | 0.6362 |
| Glu-Glu | 0.2364 | 0.1779 | 3.4229 | 0.1628 |
| Glutathione(ox) | 0.9893 | 0.9661 | NA | 1.1570 |
| Glutathione(red) | NA | NA | NA | 1.0000 |
| Gly | 1.2400 | 0.9948 | 1.3841 | 0.3811 |
| Glycerophosphorylcholine | 1.0814 | 1.1923 | 0.3550 | 1.3713 |
| Gly-Gly | 2.2431 | 0.9919 | 0.4084 | 0.3566 |
| Gly-Leu | 0.7958 | 0.5192 | 1.9021 | 0.1320 |
| Gramine | NA | NA | NA | NA |
| Guanidinoacetate | 0.7316 | 0.8850 | 1.1327 | 1.2507 |
| Guanidinosuccinate | 0.8636 | 0.5064 | 1.2823 | 1.3477 |
| Guanine | 0.1367 | 1.4413 | 1.1887 | 1.2333 |
| Guanosine | 2.1566 | 1.2898 | 0.2761 | 0.2775 |
| Harman | NA | NA | NA | NA |
| Hexylamine | NA | NA | NA | NA |
| His | 1.9157 | 1.2543 | 0.5130 | 0.3169 |
| Histamine | 0.2550 | 0.5801 | 0.2445 | 2.9204 |
| Histidinol | NA | NA | 0.7000 | 1.2250 |
| Homocarnosine | NA | NA | NA | NA |
| Homocysteine | NA | NA | NA | NA |
| Homocystine | NA | NA | NA | NA |
| Homoserine | 0.4998 | 0.2448 | 1.2176 | 2.0378 |
| Hydroxyproline | 0.0288 | 0.3466 | 0.1234 | 3.5012 |
| Hydroxyurea | NA | NA | NA | NA |
| Hypotaurine | 2.5227 | 0.8451 | 0.1494 | 0.2701 |
| Hypoxanthine | 0.8770 | 0.8811 | 1.0820 | 1.1598 |
| Ibotenate | NA | NA | NA | NA |
| Ile | 1.5402 | 0.7271 | 1.5799 | 0.1527 |
| Imidazole-4-acetate | 0.9921 | 0.5945 | 1.0836 | 1.3298 |
| Indole-3-acetaldehyde | 0.9222 | 0.7138 | 0.9417 | 1.4223 |
| Indole-3-acetamide | NA | NA | NA | NA |
| Indole-3-acetate | 0.9163 | 0.7833 | 1.3005 | NA |
| Indole-3-ethanol | 0.8312 | 0.9091 | 0.8225 | 1.4372 |
| Inosine | 1.3537 | 0.7224 | 0.9829 | 0.9410 |
| Isoamylamine | NA | NA | NA | NA |
| Isobutylamine | NA | NA | NA | NA |
| Isonicotinamide | NA | NA | NA | NA |
| Isopropanolamine | 0.0373 | 0.0292 | 0.8101 | 1.9160 |
| Kynurenine | NA | 1.0000 | NA | NA |
| Leu | 1.3093 | 0.7651 | 1.7942 | 0.1314 |
| Leu-Leu-Tyr | NA | NA | NA | NA |
| Lys | 1.1127 | 0.8041 | 1.8761 | 0.2072 |
| Lysinamide | 0.9725 | NA | 1.2967 | 0.6411 |
| Mannosamine | 0.6500 | 1.5072 | 0.2901 | 1.3753 |
| Melamine | NA | NA | NA | NA |
| Melatonin | NA | NA | NA | NA |
| Met | 0.8918 | 0.5007 | 2.3378 | 0.2697 |
| Metformin | NA | NA | NA | NA |
| Methionine sulfoxide | 1.1329 | 0.7226 | 1.7669 | 0.3776 |
| Methionine sulfoximine | NA | NA | NA | NA |
| Methylguanidine | NA | NA | NA | NA |
| Muramate | NA | NA | NA | NA |
| Muscimol | NA | NA | NA | NA |
| N1-Acetylspermidine | 0.5087 | 0.2416 | 1.1869 | 2.0629 |
| N1-Acetylspermine | NA | NA | NA | 1.0000 |
| N1,N12-Diacetylspermine | 0.1131 | NA | 0.3558 | 6.2378 |
| N1,N8-Diacetylspermidine | 0.4760 | 0.5600 | 0.7980 | 1.9040 |
| N6-Methyl-2^-deoxyadenosine | NA | NA | NA | NA |
| N6,N6,N6-Trimethyllysine | 0.6868 | 0.6932 | 1.2083 | 1.4118 |
| N8-Acetylspermidine | 0.2535 | 0.1801 | 1.1713 | 2.3951 |
| N-Acetylglucosamine | 1.0489 | 1.2981 | 0.8395 | 0.8136 |
| N-Acetylglucosylamine | 0.5256 | 1.0341 | 2.0853 | 0.3549 |
| N-Acetylhistidine | 1.1401 | 2.2638 | 0.2296 | 0.3664 |
| N-Acetylornithine | 0.2837 | 0.2631 | 1.5622 | 1.8911 |
| N-Acetylputrescine | 0.1143 | 0.1698 | 1.8259 | 1.8900 |
| N-Acetylvaline | 1.1275 | 0.2873 | 1.7953 | 0.7899 |
| N-alpha-Benzenolarginine ethylester | NA | NA | NA | NA |
| N-alpha,N-alpha-Dimethylhistidine | NA | 0.8699 | NA | 1.1301 |
| n-Butyl a-Picolinate | NA | NA | NA | NA |
| N-epsilon-Acetyllysine | 0.6863 | 0.7375 | 1.4955 | 1.0807 |
| N-gamma-Ethylglutamine | NA | NA | NA | NA |
| Nicotinamide | 0.6594 | 0.9389 | 1.3919 | 1.0098 |
| Nicotine | NA | NA | NA | NA |
| N-Methylalanine | NA | NA | 0.8691 | 1.1309 |
| N-Methylaniline | NA | NA | NA | NA |
| N-Methylglutamate | NA | NA | NA | NA |
| NMN | 0.0639 | 0.1249 | 1.9654 | 1.6117 |
| N,N-Dimethylglycine | 0.9129 | 0.9369 | 0.9449 | 1.2052 |
| N-omega-Methyltryptamine | NA | NA | NA | NA |
| Noradrenaline | NA | NA | NA | 1.0000 |
| Nornicotine | NA | NA | NA | NA |
| o-Acetylcarnitine | 1.5106 | 1.0348 | 0.6910 | 0.7636 |
| O-Acetylserine | NA | NA | NA | 1.0000 |
| Octopine | NA | 1.1929 | NA | 0.7429 |
| Octylamine | NA | NA | NA | NA |
| Ophthalmate | 0.3390 | 2.0533 | 0.2712 | 1.3366 |
| Ornithine | 0.0673 | 0.0760 | 3.4834 | 0.3733 |
| o-Succinylhomoserine | 1.0813 | 1.3949 | 0.7414 | 0.7824 |
| p-Aminobenzoate | NA | NA | NA | NA |
| Phe | 1.1406 | 0.8478 | 1.7965 | 0.2152 |
| Phenethylamine | NA | NA | NA | NA |
| Phenylethanolamine | NA | NA | NA | NA |
| Phe-Phe | NA | NA | NA | NA |
| Phosphorylcholine | 0.4439 | 0.7626 | 0.9959 | 1.5195 |
| Picolinamide | NA | NA | NA | NA |
| Pipecolate | 0.0449 | 0.0776 | 1.6788 | 2.1988 |
| Pro | 0.8537 | 0.4434 | 1.9862 | 0.7168 |
| Proline betaine | NA | 0.7930 | NA | 1.1035 |
| Pseudopelletierine | NA | NA | NA | NA |
| Pterin | NA | NA | NA | NA |
| Purine | NA | NA | NA | NA |
| Purine riboside | NA | NA | NA | NA |
| Putrescine(1,4-Butanediamine) | 0.1476 | 0.1865 | 1.1736 | 2.4924 |
| Pyrazole | NA | NA | NA | NA |
| Pyridoxal | NA | 0.7918 | 0.4312 | 1.7770 |
| Pyridoxamine | NA | NA | 0.4917 | 1.5083 |
| Pyridoxamine 5^-phosphate | NA | NA | NA | 1.0000 |
| Pyridoxine | NA | 0.5596 | 0.1371 | 1.6561 |
| Riboflavin | NA | NA | 0.6467 | 1.1178 |
| Saccharopine | 0.3936 | 2.2574 | 1.0967 | 0.3007 |
| SAH | 0.2553 | 0.3440 | 1.1325 | 2.1042 |
| SAM+ | 0.5112 | 0.1525 | 1.4170 | 1.9193 |
| Sarcosine | 0.7240 | 0.7968 | 1.1608 | 1.3185 |
| SDMA | 0.4526 | 0.4975 | 1.1295 | 1.9205 |
| Sepiapterin | NA | NA | NA | NA |
| Ser | 1.9955 | 1.0894 | 0.6479 | 0.2671 |
| Serotonin | 0.8380 | 0.7664 | 0.7146 | 1.5999 |
| S-Lactoylglutathione | NA | NA | NA | NA |
| S-Methylmethionine | NA | NA | NA | NA |
| Spermidine | 0.0998 | 0.0773 | 0.8643 | 2.9586 |
| Spermine | 0.7433 | NA | 0.6782 | 1.5144 |
| Synephrine | NA | NA | NA | NA |
| Taurine | 0.3387 | 0.1355 | 2.4121 | 1.1138 |
| Taurocyamine | NA | NA | NA | NA |
| Tetrahydropalmatine | NA | NA | NA | NA |
| Thiamine | 1.0241 | 1.7237 | 0.7807 | 0.4715 |
| Thiamine monophosphate | NA | NA | 1.0773 | 0.7680 |
| Thr | 2.2002 | 1.3606 | 0.2834 | 0.1557 |
| Thymidine | 0.7536 | 1.3522 | 0.4650 | 1.4292 |
| Thymine | 0.4852 | 2.4137 | 0.4512 | 0.6500 |
| trans-Zeatin | NA | NA | 1.0000 | NA |
| TRH | NA | NA | NA | NA |
| Trientine | NA | NA | NA | NA |
| Trigonelline | NA | 1.3035 | NA | 0.6965 |
| Trimethylamine | 0.5455 | 0.8021 | 0.6203 | 2.0321 |
| Trimethylamine N-oxide | 0.0980 | 1.9020 | NA | NA |
| Trimethylsulfonium | NA | NA | NA | NA |
| Tropine | NA | NA | NA | NA |
| Tropinone | NA | NA | NA | NA |
| Trp | 1.7007 | 1.1225 | 0.7299 | 0.4469 |
| Tryptamine | NA | NA | NA | NA |
| Tyr | 1.4202 | 0.7830 | 1.6511 | 0.1458 |
| Tyramine | NA | NA | 0.3699 | 1.2100 |
| Uracil | 1.4386 | 0.7498 | 1.0834 | 0.7283 |
| Urea | 0.9763 | 0.9909 | 1.1508 | 0.8820 |
| Uridine | 2.0239 | 0.6841 | 0.7644 | 0.5276 |
| Urocanate | 2.4794 | 1.2333 | 0.2360 | 0.0512 |
| Val | 1.3014 | 0.7336 | 1.7569 | 0.2081 |
| Xanthine | 0.9310 | 1.3319 | 0.7371 | NA |
| Xanthopterin | NA | NA | NA | NA |
| Xanthosine | 1.9751 | 0.9929 | 0.3630 | 0.5587 |
Factors:
| F1 | Organ:Cecum | Treatment:Germfree | Diet:Fiber-free |
| F2 | Organ:Cecum | Treatment:Germfree | Diet:Fiber-rich |
| F3 | Organ:Cecum | Treatment:Gnotobiote (14SM) | Diet:Fiber-free |
| F4 | Organ:Cecum | Treatment:Gnotobiote (14SM) | Diet:Fiber-rich |
