Data for (Study ST004042)

(Analysis AN006681)

Values for each metabolite have been scaled by dividing by the mean across all factors

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Metabolite	F1	F2
11,12,15-THETA	1.4770	0.7615
11,14,15-THETA	1.6263	0.6868
11b,17a,21-Trihydroxypreg-nenolone	1.0000	NA
11b,21-Dihydroxy-3,20-oxo-5b-pregnan-18-al	1.0000	NA
11-cis-Retinaldehyde	1.0000	NA
11-cis-Retinol	1.0000	NA
11H-14,15-EETA	1.0000	NA
1,2-Dihydronaphthalene-1,2-diol	1.0000	NA
12(R)-HPETE	1.0000	NA
12(S)-HPETE	1.0000	NA
15H-11,12-EETA	1.0000	NA
15(S)-HPETE	1.0000	NA
16a-Hydroxyandrost-4-ene-3,17-dione	0.9809	1.0191
16b-Hydroxyestrone	1.0000	NA
17alpha,21-Dihydroxypregnenolone	1.0000	NA
17-beta-Estradiol-3-glucuronide	1.2912	0.8544
17-Hydroxyprogesterone	NA	1.0000
19-Hydroxyandrost-4-ene-3,17-dione	0.5787	1.4213
19-Oxoandrost-4-ene-3,17-dione	1.0938	0.9062
19-Oxotestosterone	0.7339	1.2661
1a,11b-Dihydro-4,9-dimethylbenz[a]anthra[3,4-b]oxirene	1.0000	NA
(1aalpha,2beta,3alpha,11calpha)-1a,2,3,11c-Tetrahydro-6,11-dimethylbenzo[6,7]phenanthro[3,4-b]oxirene-2,3-diol	NA	1.0000
1-Methylxanthine	1.0000	NA
1-Naphthol	0.8277	1.1723
1-Nitronaphthalene-5,6-oxide	NA	1.0000
1-Nitronaphthalene-7,8-oxide	NA	1.0000
1-Pyrroline-4-hydroxy-2-carboxylate	NA	1.0000
20a-Dihydroprogesterone	1.0000	NA
20-Hydroxy-leukotriene B4	0.9122	1.0878
21-Deoxycortisol	1.0000	NA
24-Hydroxycalcitriol	1.0000	NA
2-Hydroxy-3-(4-hydroxyphenyl)propenoic acid	1.0000	NA
2-Hydroxyestrone	1.0000	NA
2-Methoxyestradiol	0.9139	1.0861
2-Methoxy-estradiol-17b 3-glucuronide	NA	1.0000
2-Methoxyestrone	0.7654	1.2346
2-Oxo-4-methylthiobutanoic acid	0.5759	1.4241
2-Oxoarginine	1.0000	NA
2-(S-Glutathionyl)acetyl glutathione	NA	1.0000
3,4-Dihydroxyphenylacetaldehyde	1.0000	NA
3,4-Dihydroxyphenylglycol	1.2661	0.7339
3a,21-Dihydroxy-5b-pregnane-11,20-dione	1.0000	NA
3a,7a,12a-Trihydroxy-5b-cholestan-26-al	NA	1.0000
3a,7a-Dihydroxycoprostanic acid	NA	1.0000
3beta,7alpha-Dihydroxy-5-cholestenoate	1.0000	NA
3beta-Hydroxypregn-5-en-20-one sulfate	NA	1.0000
3-Hydroxylidocaine	1.6648	0.3352
3-ketosphinganine	NA	1.0000
3-Methoxy-4-hydroxyphenylglycolaldehyde	1.0000	NA
4a-Carboxy-4b-methyl-5a-cholesta-8,24-dien-3b-ol	NA	1.0000
4a-Hydroxytetrahydrobiopterin	NA	1.0000
4-Guanidinobutanoic acid	1.0000	NA
4-Hydroxy-4-(methylnitrosoamino)-1-(3-pyridinyl)-1-butanone	NA	1.0000
4-Hydroxydebrisoquine	0.2285	1.7715
4-[(Hydroxymethyl)nitrosoamino]-1-(3-pyridinyl)-1-butanone	NA	1.0000
4-Hydroxyphenylacetaldehyde	1.0000	NA
4-Hydroxyphenylpyruvic acid	1.0000	NA
4-Hydroxy tolbutamide	0.9625	1.0250
4-Pyridoxic acid	NA	1.0000
4-Trimethylammoniobutanoic acid	1.0000	NA
5,10-Methylene-THF	1.0000	NA
5,6-Dihydro-5-fluorouracil	NA	1.0000
5,7,24(28)-Ergostatrienol	1.0000	NA
5-Acetylamino-6-formylamino-3-methyluracil	1.0000	NA
5a-Dihydrotestosterone sulfate	0.5358	1.9284
5-alpha-Dihydrotestosterone glucuronide	0.9549	1.1352
5-Androstenediol	1.0000	NA
5a-Pregnane-3,20-dione	1.0000	NA
5b-Dihydrotestosterone	1.0000	NA
5-Fluorouridine	NA	1.0000
5-Formiminotetrahydrofolic acid	NA	1.0000
5-Hydroxykynurenine	NA	1.0000
5-L-Glutamyl-taurine	1.0000	NA
5-Methoxyindoleacetate	1.0000	NA
5-Methyltetrahydrofolic acid	1.0000	NA
5^-Methylthioadenosine	NA	1.0000
5-phosphonooxy-L-lysine	NA	1.0000
5(S)-Hydroperoxyeicosatetraenoic acid	1.0000	NA
6-Hydroxymelatonin	NA	1.0000
6-Methylthiopurine	1.0000	NA
7,12-Dimethylbenz[a]anthracene 5,6-oxide	1.0000	NA
7,8-Dihydroneopterin	1.0000	NA
7alpha-Hydroxy-3-oxo-4-cholestenoate	1.0000	NA
7-Hydroxymethyl-12-methylbenz[a]anthracene	1.0000	NA
7-Hydroxymethyl-12-methylbenz[a]anthracene sulfate	NA	1.0000
7-Methylxanthine	1.0000	NA
8-Isoprostaglandin F2a	1.3553	0.6447
8(S)-HPETE	1.0000	NA
9-cis-Retinal	1.0000	NA
9-cis-Retinoic acid	NA	1.0000
9-cis-Retinol	1.0000	NA
9-Hydroxybenzo[a]pyrene	NA	1.0000
Acetylcholine chloride	1.0000	NA
Acetyl-CoA	NA	1.0000
Adenosine	0.8740	1.2520
ADP-ribose 2^-phosphate	1.0000	NA
Adrenic acid	NA	1.0000
Adrenosterone	0.6545	1.3455
Aflatoxin B1	NA	1.0000
all-trans-Decaprenyl diphosphate	1.0000	NA
All-trans-retinoic acid	NA	1.0000
alpha-Fluoro-beta-ureidopropionic acid	NA	1.0000
Alpha-Lactose	NA	1.0000
Alpha-Tocotrienol	0.9606	1.0788
Aminoadipic acid	1.0000	NA
Androstanedione	NA	1.0000
Androstenedione	1.0000	NA
Androsterone	1.0000	NA
Androsterone glucuronide	1.0000	NA
Anserine	0.0020	1.9980
Arachidic acid	NA	1.0000
Arachidonic acid	1.0000	NA
Argininosuccinic acid	1.0000	NA
B-Carotene	1.0000	NA
Benzo[a]pyrene	NA	1.0000
Benzo[a]pyrene-4,5-oxide	NA	1.0000
Benzo[a]pyrene-7,8-dihydrodiol-9,10-oxide	NA	1.0000
Benzo[a]pyrene-7,8-diol	1.5333	0.4667
Benzo[a]pyrene-7,8-oxide	NA	1.0000
Benzo[a]pyrene-9,10-oxide	NA	1.0000
beta-Alanyl-L-arginine	NA	1.0000
beta-Alanyl-L-lysine	NA	1.0000
Betaine	0.9614	1.0771
Beta-tocopherol	1.0327	0.9673
Bilirubin	1.3406	0.6594
Bilirubin glucuronide	1.6153	0.3847
Biliverdin	1.0000	NA
Biocytin	0.8378	1.1622
Biotin	0.9298	1.1404
Biotinyl-5^-AMP	1.0000	NA
Cadaverine	1.0000	NA
Caffeine	1.0000	NA
Calcidiol	NA	1.0000
Capric acid	NA	1.0000
Carnosine	NA	1.0000
CerP(d18:1/12:0)	1.3739	0.6261
Chenodeoxycholic acid	1.0000	NA
Chenodeoxyglycocholic acid	1.3917	0.6083
Chitin	0.5826	1.4174
Cholesterol	NA	1.0000
Cholesterol sulfate	NA	1.0000
Choline	0.6371	1.3629
Chondroitin	1.0000	NA
Citalopram aldehyde	0.9234	1.0766
CMP-N-trimethyl-2-aminoethylphosphonate	1.0000	NA
Codeine-6-glucuronide	1.0475	0.9525
Coproporphyrin III	1.0000	NA
Coproporphyrinogen I	1.0000	NA
Coproporphyrinogen III	1.0000	NA
Cortexolone	1.0000	NA
Corticosterone	1.0000	NA
Cytidine	1.0000	NA
D-4^-Phosphopantothenate	NA	1.0000
Debrisoquine	1.0000	NA
Dehydroepiandrosterone	NA	1.0000
Dehydroepiandrosterone sulfate	NA	1.0000
Deoxycorticosterone	NA	1.0000
Deoxycytidine	NA	1.0000
Deoxyguanosine	0.8740	1.2520
Deoxyinosine	0.5769	1.4231
Deoxyribose 1-phosphate	NA	1.0000
Deoxyribose 5-phosphate	NA	1.0000
D-Erythrose 4-phosphate	NA	1.0000
DG(20:0/20:0/0:0)	1.0000	NA
D-Glutamic acid	NA	1.0000
D-Glutamine	1.0000	NA
Didemethylcitalopram	NA	1.0000
Dihydrocortisol	1.0000	NA
Dihydrofolic acid	NA	1.0000
Dihydrotestosterone	1.0854	0.8292
Dihydrouracil	1.0000	NA
Dimethylglycine	1.0000	NA
D-Maltose	NA	1.0000
Docosa-4,7,10,13,16-pentaenoyl CoA	0.4457	2.1086
Docosahexaenoic acid	1.0000	NA
Dodecanoic acid	1.0000	NA
Dolichyl b-D-glucosyl phosphate	1.0000	NA
Dopamine	1.0000	NA
Dopamine 3-O-sulfate	NA	1.0000
D-Pantothenoyl-L-cysteine	0.0963	1.4518
D-Proline	NA	1.0000
D-Ribose	1.0000	NA
D-Xylose	1.0000	NA
D-Xylulose	1.0000	NA
Eicosapentaenoic acid	0.8760	1.3720
Elaidic acid	1.4887	0.5113
Enol-phenylpyruvate	1.0000	NA
Estradiol	NA	1.0000
Estrone	NA	1.0000
Estrone glucuronide	1.1388	0.9075
Estrone sulfate	1.5204	0.4796
Etiocholanedione	NA	1.0000
Etiocholanolone	1.0000	NA
Etiocholanolone glucuronide	1.0000	NA
Farnesyl pyrophosphate	1.0000	NA
Formiminoglutamic acid	NA	1.0000
Formylanthranilic acid	NA	1.0000
(Gal)2 (GlcA)1 (Xyl)1 (Ser)1	1.0000	NA
(Gal)2 (Xyl)1 (Ser)1	NA	1.0000
Gamma-Aminobutyric acid	1.0000	NA
Geranylgeranyl-PP	1.0000	NA
(GlcA)1 (GlcNAc)1	NA	1.0000
Gluconic acid	1.0000	NA
Gluconolactone	NA	1.0000
Glutarylcarnitine	NA	1.0000
Glyceric acid	1.0000	NA
Glycerol 3-phosphate	NA	1.0000
Glycocholic acid	1.0397	0.9735
Guanosine	1.2857	0.7143
Guanosine monophosphate	0.8103	1.1897
Gulonic acid	1.0000	NA
Heptadecanoic acid	1.0000	NA
Homocarnosine	1.2673	0.7327
Homovanillic acid	1.0000	NA
Indolepyruvate	1.0000	NA
L-3-Hydroxykynurenine	NA	1.0000
L-4-Hydroxyglutamate semialdehyde	NA	1.0000
L-Alpha-aminobutyric acid	1.0000	NA
L-Arabinose	1.0000	NA
L-Asparagine	NA	1.0000
Lc4Cer	NA	1.0000
L-Cystathionine	NA	1.0000
L-Cystine	1.0000	NA
Leukotriene A4	1.0000	NA
Leukotriene B4	1.0000	NA
Leukotriene C4	1.3167	0.8944
Leukotriene D4	1.0000	NA
L-Glutamic acid	NA	1.0000
L-Glutamine	1.0000	NA
L-Glyceric acid	1.0000	NA
L-Gulonolactone	NA	1.0000
Linoleic acid	1.0000	NA
Liothyronine	1.3542	0.6458
L-Methionine	NA	1.0000
L-Octanoylcarnitine	NA	1.0000
L-Proline	NA	1.0000
L-Threo-2-pentulose	1.0000	NA
L-Tryptophan	0.3916	1.6084
L-Tyrosine	0.7777	1.4446
L-Valine	NA	1.0000
LysoPC(0:0/18:0)	1.2288	0.5423
LysoSM(d18:1)	1.5273	0.4727
Maleylacetoacetic acid	1.3265	0.6735
Malonyl-Carnitin	NA	1.0000
Maltotriose	1.0000	NA
Menaquinol	NA	1.0000
Metanephrine	NA	1.0000
Mevalonic acid	NA	1.0000
Myristic acid	1.0000	NA
N10-Formyl-THF	NA	1.0000
N(1)-(5-Phospho-D-ribosyl)glycinamide	NA	1.0000
N(2)-Formyl-N(1)-(5-phospho-D-ribosyl)glycinamide	NA	1.0000
N6,N6,N6-Trimethyl-L-lysine	0.9086	1.0914
NA	1.0336	0.9664
N-Acetylaspartylglutamylglutamate	1.0000	NA
N-Acetyl-D-Glucosamine 6-Phosphate	1.0000	NA
N-Acetyl-D-mannosamine 6-phosphate	1.0000	NA
N-Acetylneuraminate	1.0031	0.9969
N-Acetylputrescine	1.0000	NA
NADH	1.0000	NA
Naphthalene-1,2-diol	1.0000	NA
Naphthalene epoxide	0.8277	1.1723
Nervonic acid	0.6622	1.3378
Nicotinamide riboside	1.8231	0.1769
Nicotinamide ribotide	NA	1.0000
Nicotinic acid adenine dinucleotide phosphate	1.0000	NA
N(omega)-Hydroxyarginine	NA	1.0000
NPC	1.0000	NA
Obtusifoliol	NA	1.0000
Omeprazole	0.0325	1.9675
OPC4-CoA	NA	1.0000
O-Phospho-4-hydroxy-L-threonine	NA	1.0000
Ophthalmic acid	1.0000	NA
Orotidylic acid	NA	1.0000
Ortho-Hydroxyphenylacetic acid	1.0000	NA
Oxalacetic acid	NA	1.0000
Oxidized glutathione	0.9873	1.0127
Oxoadipic acid	1.0000	NA
Oxoglutaric acid	NA	1.0000
Palmitic acid	1.0000	NA
Pantothenic acid	1.1199	0.7602
Pentadecanoic acid	1.0000	NA
Pentaglutamyl folate	1.0632	0.9368
Phenylacetic acid	1.0000	NA
Phenylethylamine	1.0000	NA
Phenylpyruvic acid	1.0000	NA
p-Hydroxyphenylacetic acid	1.0000	NA
Pregnenolone	1.0000	NA
Presqualene diphosphate	1.0000	NA
Propinol adenylate	1.0000	NA
Prostaglandin D2	1.1415	0.8585
Prostaglandin E2	1.1415	0.8585
Prostaglandin F2a	1.3883	0.8059
Prostaglandin H2	0.1713	1.8287
Prostaglandin I2	1.9874	0.0126
Protoporphyrin IX	1.4344	0.5656
Protoporphyrinogen IX	1.0000	NA
Putrescine	1.0000	NA
Pyridoxamine	1.0000	NA
Pyroglutamic acid	NA	1.0000
Pyrrolidonecarboxylic acid	NA	1.0000
Pyrroline hydroxycarboxylic acid	NA	1.0000
(R)-3-Ureidoisobutyrate	1.0000	NA
(R)-b-aminoisobutyric acid	1.0000	NA
Retinal	1.0000	NA
Retinoyl b-glucuronide	1.0000	NA
Riboflavin	1.6605	0.3395
Riboflavin reduced	1.0000	NA
S-Adenosylhomocysteine	NA	1.0000
(S)-b-aminoisobutyric acid	1.0000	NA
Selenomethionine	NA	1.0000
Serotonin	1.0000	NA
SN-38	NA	1.0000
SN38 glucuronide	1.0000	NA
Sphinganine 1-phosphate	0.7663	1.4674
Sphingosine	NA	1.0000
Sphingosine 1-phosphate	1.9682	0.0318
Squalene	NA	1.0000
Stachyose	1.0000	NA
Stearidonic acid	0.9046	1.0954
Sucrose	NA	1.0000
Tamoxifen N-oxide	NA	1.0000
T antigen	1.5597	0.4403
Taurochenodesoxycholic acid	1.2377	0.7623
Taurocholic acid	0.9968	1.0032
Testosterone	NA	1.0000
Tetracosahexaenoic acid	NA	1.0000
Tetracosanoic acid	1.0000	NA
Tetrahydrocortisol	NA	1.0000
Tetrahydrofolic acid	0.5742	1.2839
Tetrahydrofolyl-[Glu](n)	1.0000	NA
TG(8:0/8:0/8:0)	1.0652	0.9348
THF-L-glutamate	1.0000	NA
Thiamine	NA	1.0000
Thiamine monophosphate	NA	1.0000
Thiamine pyrophosphate	NA	1.0000
Thromboxane A2	1.1415	0.8585
Thymidine	NA	1.0000
Thyroxine	1.0000	NA
trans-3,4-Dihydro-3,4-dihydroxy-7,12-dimethylbenz[a]anthracene	1.0000	NA
trans-5,6-Dihydro-5,6-dihydroxy-7,12-dimethylbenz[a]anthracene	1.0000	NA
Trehalose	NA	1.0000
Triiodothyronine sulfate	1.0000	NA
Trypanothione	1.0000	NA
Tyramine-O-sulfate	0.2364	1.7636
Uracil	1.0000	NA
Ureidopropionic acid	NA	1.0000
Uridine	1.2894	0.5658
Uridine 5^-monophosphate	NA	1.0000
Uridine triphosphate	1.0000	NA
Urobilinogen	1.2455	0.5090
Vaccenic acid	1.4887	0.5113
Vitamin A	1.0000	NA
Vitamin D3	1.5733	0.4267
Xanthosine	NA	1.0000
(Xyl)1 (Ser)1	NA	1.0000

Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study

Factors:

F1	Sample source:wildtype | Treatment:GFP
F2	Sample source:wildtype | Treatment:P2_HNF4a