Data for Quantitative Metabolomics by 1H-NMR and LC-MS/MS Confirms Altered Metabolic Pathways in Diabetes (Study ST000091)

(Analysis AN000145)

Values for each metabolite have been scaled by dividing by the mean across all factors

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MetaboliteF1F2F3
1MH_1-Methylhistidine^ 0.8605 1.0588 1.0872
3MH_3-Methylhistidine^ 1.0145 0.9910 0.9936
AABA_alpha-Amino-N-butyric-acid 0.9494 1.1898 0.8819
AADA_alpha-Aminoadipic-acid 0.9361 1.3915 0.7159
Aileu_allo-Isoleucine 0.8498 1.2226 0.9523
Ala_Alanine 0.9991 0.9778 1.0207
Ans_Anserine NA 1.1314 0.8686
Arg_Arginine 1.1163 0.9781 0.9033
Asn_Asparagine 1.1174 0.8671 1.0008
Asp_Aspartic Acid 0.9080 1.1024 1.0010
BAIB_beta-Aminoisobutyric-acid 1.2839 0.9947 0.7208
B-ala_beta-Alanine^ 0.9616 0.9917 1.0458
Carn_Carnosine 1.0374 0.9105 0.9944
Cit_Citrulline 1.0409 0.9611 0.9937
Cys_Cystine 1.2985 0.7106 0.9587
Cyst1_Cystathionine 1 1.2806 1.2030 0.5390
Cyst2_Cystathionine 2 NA NA NA
EA_Ethanolamine 1.0979 0.9660 0.9323
GABA_gamma-Amino-N-butyric-acid 1.0880 0.9552 0.9518
Gln_Glutamine 1.1083 0.8778 1.0003
Glu_Glutamic Acid 1.0630 0.9019 1.0242
Gly_glysine 1.0658 0.7973 1.1143
HCys_Homocystine NA NA NA
His_Histidine 1.0489 0.9866 0.9631
HL1_Hydroxylysine 1 0.9858 1.0060 1.0088
HL2_Hydroxylysine 2 1.0805 0.9381 0.9745
HyPro_Hydroxyproline 0.9421 0.9438 1.1079
iLeu_Isoleucine 0.7754 1.5987 0.6925
Leu_Leucine 0.8043 1.5090 0.7432
Lys_Lysine 1.0147 0.9827 1.0007
Met_Methionine 1.0855 0.9318 0.9751
NH3_Ammonia 0.9966 0.9676 1.0322
Orn_Ornithine 1.0013 1.0811 0.9267
PEA_Phosphoethanolamine 1.5033 0.6943 0.7889
Phe_phenylalanine 1.0116 1.0581 0.9368
Pro_Proline 0.9614 1.0007 1.0379
PSer_Phosphoserine 1.0245 1.0411 0.8894
Sar_Sarcosine 1.0276 0.9581 1.0096
Ser_Serine 1.0608 0.8860 1.0406
Tau_Taurine 1.0386 1.0194 0.9442
Thr_Threonine 1.1921 0.8438 0.9468
Trp_Trypotphan 0.9310 1.0602 1.0156
Tyr_Tyrosine 0.9432 1.1065 0.9621
Val_Valine 0.9083 1.3154 0.8113
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Factors:

F1Treatment:Control
F2Treatment:Insulin Deprived
F3Treatment:Insulin Treatment
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