Data for 13C targeted metabolomics (Study ST000147)
(Analysis AN000234)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 |
|---|---|---|---|---|---|---|---|---|
| Alanine_123 | 0.1605 | 0.8237 | 0.3197 | 1.3853 | 0.2103 | 1.4649 | 0.6901 | 2.9455 |
| Alanine_123_13C_1 | 0.5769 | 1.2041 | 0.9819 | 2.8613 | 0.2506 | 0.5981 | 0.1278 | 0.7883 |
| Alanine_123_13C_2 | NA | NA | NA | NA | NA | NA | NA | NA |
| Alanine_123_13C_3 | NA | NA | NA | NA | NA | NA | NA | NA |
| alpha-Ketoglutarate_12345 | 0.5633 | 1.0680 | 0.9716 | 1.3930 | 0.3076 | 1.5118 | 0.4157 | 1.7689 |
| alpha-Ketoglutarate_12345_13C_1 | 0.9262 | 0.2701 | 0.5410 | NA | 0.9653 | 1.4624 | 1.7178 | 1.5464 |
| alpha-Ketoglutarate_12345_13C_2 | 2.0664 | 0.2188 | 2.3557 | 0.5887 | 0.7211 | 0.5733 | 1.0340 | 0.1629 |
| alpha-Ketoglutarate_12345_13C_3 | 0.3976 | 0.0066 | 0.5178 | 0.0898 | 1.4445 | 0.3367 | 3.1728 | 0.8473 |
| alpha-Ketoglutarate_12345_13C_4 | 1.9621 | NA | 0.8191 | NA | 0.7937 | NA | 0.8798 | 0.2108 |
| alpha-Ketoglutarate_12345_13C_5 | 0.2134 | NA | 0.0532 | NA | 0.7615 | 0.3741 | 2.4065 | 1.2979 |
| Aspartate_1234 | 0.1083 | 1.7192 | 0.2811 | 1.8250 | 0.0558 | 1.8211 | 0.1265 | 2.0630 |
| Aspartate_1234_13C_1 | 0.8939 | 0.3709 | 1.1623 | 0.3350 | 0.7876 | NA | 1.8000 | 1.0277 |
| Aspartate_1234_13C_2 | 0.9415 | 0.2418 | 2.1000 | 0.1143 | 0.5685 | 0.0911 | 1.8314 | NA |
| Aspartate_1234_13C_3 | 0.9839 | 0.1477 | 1.2222 | 0.1622 | 1.0793 | 0.1443 | 3.5467 | 0.4295 |
| Aspartate_1234_13C_4 | 0.1035 | 0.0891 | 0.1998 | 0.1061 | 1.0591 | 0.1840 | 4.8553 | 0.5035 |
| Fumarate_1234 | 0.6001 | 1.1792 | 1.1514 | 1.2709 | 0.2962 | 1.4504 | 0.5887 | 1.4631 |
| Fumarate_1234_13C_1 | 0.7812 | 1.1233 | 1.3080 | 1.1948 | 0.4373 | 1.2064 | 0.8023 | 1.1467 |
| Fumarate_1234_13C_2 | 0.7938 | NA | 0.9886 | NA | 0.5997 | NA | 1.6179 | NA |
| Fumarate_1234_13C_3 | 0.9607 | 0.0473 | 1.0624 | NA | 0.9580 | 0.0227 | 2.7037 | 0.2761 |
| Fumarate_1234_13C_4 | 0.0587 | 0.0885 | 0.0783 | 0.0665 | 0.9231 | 0.6533 | 3.8934 | 1.9271 |
| Glutamate_12345 | 1.3974 | 0.9632 | 1.7886 | 1.1173 | 0.4884 | 0.8819 | 0.4823 | 0.8809 |
| Glutamate_12345_13C_1 | 2.3277 | 0.0969 | 1.3635 | 0.0702 | 2.1112 | 0.1501 | 1.7697 | 0.1108 |
| Glutamate_12345_13C_2 | 3.1888 | 0.1888 | 2.5061 | 0.2067 | 0.7878 | 0.1268 | 0.8520 | 0.1430 |
| Glutamate_12345_13C_3 | 1.2180 | 0.0453 | 0.5831 | 0.0240 | 2.2879 | 0.3123 | 3.0141 | 0.5153 |
| Glutamate_12345_13C_4 | 2.8512 | 0.1463 | 1.7202 | 0.1102 | 0.9381 | 0.2715 | 1.4612 | 0.5012 |
| Glutamate_12345_13C_5 | 0.0913 | 0.0052 | 0.0350 | 0.0023 | 2.0792 | 0.5245 | 3.8856 | 1.3769 |
| Glutamine_12345 | 0.8652 | 3.3672 | 0.7844 | 2.8703 | 0.0126 | 0.0495 | 0.0168 | 0.0340 |
| Glutamine_12345_13C_1 | 0.9770 | 1.7111 | 1.5912 | 3.9782 | 0.2740 | 1.0831 | 0.1326 | 0.4232 |
| Glutamine_12345_13C_2 | 0.8588 | 1.9660 | 0.4786 | 2.3318 | 0.2838 | 1.3461 | 0.2992 | 0.5838 |
| Glutamine_12345_13C_3 | 0.0089 | 0.0297 | 0.0056 | 0.0063 | 0.4360 | 3.1143 | 0.6599 | 2.7454 |
| Glutamine_12345_13C_4 | 0.2423 | 0.4259 | 0.2421 | 0.0727 | 0.5628 | 2.8868 | 0.6996 | 1.9969 |
| Glutamine_12345_13C_5 | 0.0003 | 0.0009 | 0.0002 | 0.0003 | 0.3830 | 2.8932 | 0.6057 | 2.4504 |
| Lactate_123 | 0.2568 | 1.0212 | 0.2539 | 1.0563 | 0.4071 | 2.3680 | 0.4682 | 2.1686 |
| Lactate_123_13C_1 | 0.4407 | 1.9282 | 0.4664 | 2.0109 | 0.1105 | 1.5139 | 0.1023 | 1.4270 |
| Lactate_123_13C_2 | 0.7914 | 3.1644 | 0.7568 | 3.1413 | 0.0064 | 0.0575 | 0.0120 | 0.0702 |
| Lactate_123_13C_3 | 0.1624 | 0.8935 | 0.2215 | 0.9679 | 0.2610 | 1.5566 | 0.6506 | 3.2866 |
| Oxaloacetate_1234 | 1.1038 | NA | 0.8443 | NA | NA | NA | NA | NA |
| Oxaloacetate_1234_13C_1 | NA | NA | 1.0000 | NA | NA | NA | NA | NA |
| Oxaloacetate_1234_13C_2 | 1.1721 | NA | 0.8279 | NA | NA | NA | NA | NA |
| Oxaloacetate_1234_13C_3 | NA | NA | NA | NA | NA | NA | NA | NA |
| Oxaloacetate_1234_13C_4 | NA | NA | NA | NA | NA | NA | NA | NA |
| Pyruvate_123 | 0.0827 | 0.4608 | 0.1509 | 1.6924 | 0.1331 | 1.1464 | 0.2920 | 4.0418 |
| Pyruvate_123_13C_1 | 0.1400 | 1.3243 | 0.4161 | 3.5793 | 0.1470 | 0.7042 | 0.1931 | 1.2271 |
| Pyruvate_123_13C_2 | 0.2699 | 1.3317 | 0.5193 | 5.6494 | 0.0127 | 0.0361 | 0.0325 | 0.1484 |
| Pyruvate_123_13C_3 | 0.0377 | 0.1388 | 0.0522 | 1.0675 | 0.0684 | 0.7571 | 0.4078 | 5.4705 |
Factors:
| F1 | Treatment:13C glucose labeled | Cell type:Cloned Jurkat cell mid level Noxa | Harvest:cells |
| F2 | Treatment:13C glucose labeled | Cell type:Cloned Jurkat cell mid level Noxa | Harvest:spent medium |
| F3 | Treatment:13C glucose labeled | Cell type:Noxa overexpressed Jurkat cell | Harvest:cells |
| F4 | Treatment:13C glucose labeled | Cell type:Noxa overexpressed Jurkat cell | Harvest:spent medium |
| F5 | Treatment:13C glutamine labeled | Cell type:Cloned Jurkat cell mid level Noxa | Harvest:cells |
| F6 | Treatment:13C glutamine labeled | Cell type:Cloned Jurkat cell mid level Noxa | Harvest:spent medium |
| F7 | Treatment:13C glutamine labeled | Cell type:Noxa overexpressed Jurkat cell | Harvest:cells |
| F8 | Treatment:13C glutamine labeled | Cell type:Noxa overexpressed Jurkat cell | Harvest:spent medium |
