Data for 13C mass isotopomer analysis (LCMS flux studies) MLL-AF9 (part III) (Study ST000170)

(Analysis AN000447)

Values for each metabolite have been scaled by dividing by the mean across all factors

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MetaboliteF1F2F3
2 or 3-phosphoglycerate 1.4960 0.5877 0.4621
6-Phosphogluconate 0.9504 0.9348 1.1148
Acetyl-CoA 1.4861 0.2709 NA
Adenosine diphosphate 1.1509 1.4005 0.4486
Adenosine monophosphate 0.2974 2.1503 0.5524
Adenosine triphosphate 1.0951 1.0163 0.8885
Citrate or Isocitrate 0.9243 1.0306 1.0451
Erythrose 4-phosphate 0.8039 1.1859 1.0103
Fructose 1,6-bisphosphate 0.9800 1.6842 0.3358
Malate 1.5534 0.9443 0.5023
Nicotinamide Adenine Dinucleotide oxidized 1.3765 0.4982 1.1253
Nicotinamide Adenine Dinucleotide reduced 1.4559 0.9488 0.3674
Phosphoenolpyruvate 0.8567 1.1433 NA
Ribose-5-phosphate or xylulose 5-phosphate 0.8553 1.1956 0.9491
Sedoheptulose 7-phosphate 1.0830 1.1932 0.7238
Sucrose NA NA 1.0000
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Factors:

F1GENOTYPE:AMPKαfl/fl | GROUP:Bone marrow
F2GENOTYPE:AMPKαfl/fl | GROUP:Spleen
F3GENOTYPE:AMPKαΔ/Δ | GROUP:Bone marrow
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