Data for Analysis of DJ-1 Knockout Mouse Brains (Study ST000260)

(Analysis AN000415)

Values for each metabolite have been scaled by dividing by the mean across all factors

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MetaboliteF1F2F3F4
1,2-dipalmitoylglycerol 1.0616 0.7983 1.0153 1.0516
1,5-anhydroglucitol (1,5-AG) 1.2516 0.7483 1.2728 0.7640
1-palmitoylglycerol (1-monopalmitin) 1.0430 0.9693 1.0654 0.9379
24(S)-hydroxycholesterol 0.9682 0.9987 1.0865 0.9598
2-aminoadipate 1.1631 1.1493 0.9116 0.8507
2-hydroxyglutarate 1.0197 1.0670 0.9623 0.9716
2-pyrrolidinone 1.0588 0.9315 1.1035 0.9211
3-phosphoglycerate 0.8986 0.8925 1.0309 1.1200
3-phosphoserine 0.9357 0.9285 1.1506 0.9800
4-acetamidobutanoate 1.0937 0.9736 1.0132 0.9363
5,6-dihydrouracil 0.9418 1.0937 0.9480 1.0241
7-alpha-hydroxycholesterol 0.9349 1.0544 1.1939 0.8694
7-beta-hydroxycholesterol 0.9711 0.9430 1.2076 0.9016
adenine 0.9995 0.9712 1.0745 0.9625
alanine 0.9688 1.0627 0.9860 0.9947
allo-threonine 1.0958 1.1143 0.9552 0.8903
alpha-ketoglutarate 0.8202 0.9111 1.1461 1.0991
arabinose 0.9341 1.1024 0.9583 1.0167
ascorbate (Vitamin C) 0.9478 1.0007 1.0256 1.0195
aspartate 1.0508 0.9636 1.0772 0.9267
benzoate 0.9995 1.0326 0.8469 1.0948
beta-alanine 1.0963 0.9463 1.0787 0.9023
chiro-inositol 0.8607 0.9144 1.1008 1.0824
cholesterol 0.9976 0.9737 1.0630 0.9710
cis-vaccenate (18:1n7) 0.9685 0.9841 1.0423 1.0018
citrate 0.9484 1.0942 1.0107 0.9718
cystathionine 0.9318 0.9820 1.0087 1.0559
cysteine 0.9743 1.4593 0.8318 0.8583
cysteinylglycine 1.0117 1.0856 1.0302 0.9151
dehydroascorbate 0.8857 1.4088 0.9199 0.8305
desmosterol 1.2493 0.9274 1.0117 0.9181
dopamine 0.9834 1.0549 0.9661 1.0036
erythritol 1.0606 0.9011 1.0989 0.9421
erythronate* 1.0068 1.0403 1.0021 0.9681
ethanolamine 1.0137 1.1007 1.0318 0.9029
fructose 1.1362 0.6437 1.2670 0.9203
fumarate 1.0177 1.0723 0.9997 0.9418
galactitol (dulcitol) 1.0346 1.0914 0.9930 0.9221
gamma-aminobutyrate (GABA) 1.0333 0.9852 1.0462 0.9496
glucose 0.8636 0.9522 0.9496 1.1699
glucose-6-phosphate (G6P) 0.8058 1.1702 0.9446 1.0808
glycerol 0.9990 1.0245 1.0154 0.9739
glycerol 2-phosphate 0.9926 1.0481 0.9911 0.9822
glycerol 3-phosphate (G3P) 0.9982 0.9876 1.0414 0.9780
glycerophosphoethanolamine 0.9386 1.0629 0.9836 1.0191
glycine 1.0181 1.0347 0.9956 0.9681
homoserine 0.9802 0.9326 1.0787 0.9980
inositol 1-phosphate (I1P) 0.8926 1.0811 1.0086 1.0235
inositol 4-phosphate 0.6966 1.2509 0.9280 1.1247
Isobar: pentulose 5-phosphates 0.8430 1.3181 0.9283 0.9728
lactate 0.9943 1.0169 0.9683 1.0175
lathosterol 1.3482 0.9523 0.9507 0.7779
malate 0.9475 1.0753 0.9775 1.0092
mannitol 0.9308 0.9979 1.0581 1.0096
myo-inositol 0.9953 0.9981 1.0061 1.0001
oleate (18:1n9) 0.9653 0.9941 1.0556 0.9881
ornithine 1.0623 1.0006 0.9695 0.9758
palmitoyl sphingomyelin 1.0166 0.9492 0.9848 1.0308
phosphate 0.9836 1.0128 1.0027 1.0022
putrescine 1.0075 0.8980 1.0686 1.0067
pyrophosphate (PPi) 1.2298 0.9943 0.9485 0.8698
ribose 0.9724 1.0965 1.0547 0.9193
ribose 5-phosphate 0.8124 1.7594 0.6580 0.9226
sarcosine (N-Methylglycine) 0.9789 0.9347 1.0529 1.0170
scyllo-inositol 1.1106 0.8390 0.9856 1.0285
serine 1.0756 1.0500 0.9605 0.9417
sorbitol 0.9998 0.9065 1.0805 0.9982
stearamide 0.9006 1.2494 0.9279 0.9727
stearoyl sphingomyelin 1.0104 0.9284 1.0741 0.9814
taurine 0.9645 0.9515 1.0403 1.0267
trans-4-hydroxyproline 0.9533 0.8023 1.1807 1.0231
UDP-galactose 0.9505 0.9715 1.1458 0.9456
uracil 0.9993 1.0347 1.0219 0.9624
urea 0.9445 0.9466 1.1222 0.9833
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Factors:

F1Sex:F | Genotype:DJ-1 Knockout
F2Sex:F | Genotype:WT
F3Sex:M | Genotype:DJ-1 Knockout
F4Sex:M | Genotype:WT
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