Data for Metabolomic analysis on samples from rats expressing human amylin (cardiac tissue). (Study ST000347)

(Analysis AN000563)

Values for each metabolite have been scaled by dividing by the mean across all factors

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MetaboliteF1F2
1-Dodecanol 0.9390 1.0152
2-Aminoadipic acid 1.0059 0.9941
2-Hydroxybiphenyl 0.9980 1.0018
2-Hydroxypyridine 1.0048 0.9952
2-Phosphoglyceric acid 1.0050 0.9933
5-Aminovaleric acid 1.0000 NA
5-Cholesten-3-beta-7-alpha-diol 1.0034 0.9794
6-Hydroxynicotinic acid 1.0065 0.9935
6-Methyluracil 1.0000 NA
7H-Purine/Phenylalanine 1.0013 0.9991
Adenosine-5^-monophosphate 1.0344 0.9450
Alanine 0.9898 1.0102
Aldohexoses (unoximated) 1.0408 0.9592
Aldopentose-5-phosphate 1.0001 0.9999
Aldopentoses 0.9761 1.0239
alpha-Monopalmitin 0.9979 1.0021
alpha-Monostearin 0.9985 1.0015
alpha-Tocopherol 1.0119 0.9881
Aminomalonic acid 1.0042 0.9944
Arachidic acid 1.0002 0.9998
Arachidonic acid (also Eicosapentaenoic acid) 0.9773 1.0227
Aspartic acid 1.0133 0.9867
Benzoic acid 0.9965 1.0035
beta-Alanine or 3-Aminoisobutyric acid 0.9330 1.0287
beta-Hydroxybutyric acid 1.0934 0.9066
beta-Monopalmitin 0.9890 1.0110
beta-Monostearin 0.9989 1.0011
beta-Sitosterol 1.0145 0.9855
C10 hydrocarbon 0.9992 1.0008
C11 hydrocarbon 0.9960 1.0035
C12 hydrocarbon 0.9925 1.0126
C13 hydrocarbon 0.9969 1.0031
C15 hydrocarbon 1.0013 0.9987
C17 hydrocarbon 1.0049 0.9958
C19 hydrocarbon 1.0060 0.9985
C22 hydrocarbon 1.0170 0.9659
Campesterol 1.0233 0.9767
Chenodeoxycholic acid NA 1.0000
Cholesterol 1.0026 0.9974
Citric acid/isocitric acid 0.9747 1.0253
Creatinine 0.9948 1.0052
Decamethyltetrasiloxane 1.0228 0.9727
Dehydroascorbic acid 0.9797 1.0203
deuterated Myristic Acid (RTL std) 0.9993 1.0007
Dihydroxyacetone phosphate 0.9856 1.0144
Docosahexaenoic acid 0.9838 1.0162
Docosanoic acid 0.9859 1.0283
Dodecamethylpentasiloxane 1.0332 0.9668
Erythronic acid/Threonic acid 1.0049 0.9951
Ethanolamine 0.9697 1.0303
Fructose 1,6-bisphosphate 1.0000 NA
Fructose-6-phosphate 1.0354 0.9646
Fructose or similar ketohexose 1.1117 0.8883
Fumaric acid 1.0180 0.9820
gamma-Hydroxybutyric acid 1.0243 0.9660
Gentisic acid 0.9855 1.0116
Gluconic acid-6-phosphate 1.0045 0.9955
Glucose-6-phosphate or similar 1.0429 0.9571
Glucose and other aldohexoses 1.0246 0.9754
Glutamic acid 1.0148 0.9852
Glutamine 1.0012 0.9997
Glutathione (reduced) 0.9878 1.0140
Glyceric acid 0.9590 1.0205
Glycerol 0.9765 1.0235
Glycerol 1-phosphate 1.0473 0.9527
Glycine 0.9745 1.0255
Glyoxylic acid 1.0120 0.9940
Guanosine 1.0274 0.9863
Heptadecanoic acid/Octadecanol 1.0032 0.9968
Hexadecanol/Pentadecanoic acid 0.9786 1.0214
Hexanoic acid 0.9933 1.0134
Hexitols 1.1141 0.8859
Hexosamine 1.0274 0.9726
Hydroquinone NA 1.0000
Hydroxyprolines 0.9946 1.0081
Hypotaurine 0.9785 1.0215
Hypoxanthine 0.9746 1.0254
Inosine 5^-monophosphate 1.0000 NA
Inosine/Adenosine 0.9986 1.0014
Isoleucine/Leucine 1.0136 0.9864
Ketopentose-5-phosphate 0.9963 1.0037
Lactic acid 1.0041 0.9959
Linoleic acid 1.0138 0.9862
Lysine 0.9274 1.0726
Malic acid 1.0119 0.9881
Malonic acid 1.0162 0.9838
Maltose or similar disaccharide 0.9739 1.0261
Methionine 0.9990 1.0021
MSTFA artifact 1.0139 0.9861
Myoinositol 1.0118 0.9882
Myoinositol-2-phosphate 1.0104 0.9909
Myristic acid or Pentadecanol 0.9955 1.0045
N-Acetylaspartic acid NA 1.0000
N-Acetylneuraminic acid 0.9846 1.0154
Nicotinamide 0.9973 1.0027
Nonadecanoic acid 1.0043 0.9894
O-Benzyltyrosine 1.0071 0.9917
Oleic acid 1.0039 0.9961
O-Methylphosphate 1.0212 0.9788
O-Phosphocolamine 1.0053 0.9947
Palmitic acid 0.9976 1.0024
Palmitoleic acid 0.9068 1.0186
Pantothenic acid 0.9616 1.0384
Pentitols 0.9997 1.0003
Phenol 0.9254 1.0746
Phenylalanine 0.9717 1.0283
Phosphoenolpyruvic acid 1.0017 0.9983
Phosphoric acid 0.9935 1.0065
Proline 0.9871 1.0129
Prunetin or similar isoflavone 1.0110 0.9343
Pyrophosphate 0.9925 1.0064
Pyruvic acid 1.0255 0.9703
Serine 0.9393 1.0607
Squalene 1.0052 0.9948
Stearic acid 1.0006 0.9994
Succinic acid 1.0027 0.9919
Sucrose and similar disaccharides 1.0024 0.9980
Taurine 1.0118 0.9865
Tetradecanedioic acid 1.0331 0.9945
Threitol/erythritol 1.0000 NA
Threonine 0.9803 1.0197
Thymine 1.0050 0.9801
trans,trans-Muconic acid 0.9768 1.0271
Tris 0.9980 1.0012
Trisaccharide 1.0321 0.9679
Tryptophan NA 1.0000
Tyramine NA 1.0000
Tyrosine 0.9693 1.0307
Unknown-possibly propylene glycol 1.1213 0.8787
Uracil 0.9850 1.0150
Urea 1.0370 0.9630
Uridine/pseudouridine 1.0193 0.9807
Valine 1.0284 0.9716
Xanthine 0.9027 1.0556
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Factors:

F1Genotype:HIP
F2Genotype:WT
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