Data for Toxicokinetics and Metabolomic Disrupting of the Flame Retardant Mixture Firemaster 550 (Study ST000415)

(Analysis AN000657)

Values for each metabolite have been scaled by dividing by the mean across all factors

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MetaboliteF1F2F3F4F5F6
1,5-anhydroglucitol 0.9851 1.1038 0.9016 0.8530 1.0283 1.0838
1-monopalmitin 0.9569 1.0437 0.6417 1.2240 1.1255 1.0080
1-monostearin 0.9279 1.0438 0.8646 1.2224 0.8956 1.0597
2-hydroxybutanoic acid 0.9058 1.0241 0.8437 0.7011 1.2435 1.3168
2-monopalmitin 0.9252 1.1554 0.7128 0.9508 1.3121 0.9035
alanine 0.9219 1.0653 0.9694 0.9027 1.0732 1.0740
alpha-ketoglutarate 0.7117 0.7754 0.4431 0.8500 1.3999 2.0764
aminomalonic acid 0.9531 1.0176 0.9036 0.7311 1.0297 1.3794
arachidiic acid 0.8898 1.1302 0.9211 0.9551 1.0894 1.0044
aspartate minor 0.7982 0.9759 1.2320 1.1437 0.9260 1.0371
behenic acid 1.5103 1.0063 1.2495 0.1933 1.1268 0.6556
benzoic acid 0.8442 1.1101 1.0430 0.9980 1.0209 1.0066
beta alanine 0.9862 0.9108 0.8256 0.7542 1.3975 1.1773
beta-hydroxybutyric acid 0.9857 1.1624 0.8914 0.6633 1.0532 1.1699
cellobiose 0.8181 1.1126 0.9046 0.7187 1.3483 1.1324
citric acid 0.9171 0.9916 0.9584 0.7888 1.1473 1.2424
creatine major dehydrated TMS3 0.7872 0.9575 1.1259 0.9759 1.1363 1.1449
cystine 0.9697 0.8849 0.8082 0.6575 1.7160 1.0365
enolpyruvate nist 1.0873 1.3050 0.7441 0.6612 1.0082 0.9981
fructose 0.9687 1.1123 0.9877 0.8865 0.9478 1.0564
fructose 2 1.0161 1.1362 0.9861 0.8813 0.9399 0.9642
glucose 0.7822 1.0064 0.8702 0.9083 1.4419 1.0968
glucose-1-phosphate 0.9494 1.0096 1.0595 0.8933 0.9596 1.1490
glucose 2 0.8125 0.9946 0.8845 0.9038 1.4403 1.0608
glucose-6-phosphate major 1.1214 0.7979 0.2239 0.1545 2.5326 1.2101
glutamic acid 2TMS 1.0689 1.2508 0.8351 0.7287 0.9544 1.0023
glutamine 3TMS major 0.8190 0.9735 0.6154 0.6955 1.6920 1.3082
glycerol 0.8493 1.2716 0.6980 0.6510 1.2478 1.2219
glycine 0.9547 0.8777 0.8897 0.8215 1.4126 1.1277
glycolic acid 0.9292 1.1244 1.0564 0.8412 0.9822 1.0399
guanosine 0.9044 1.5342 0.6509 0.8024 1.2844 0.6045
heptadecanoic acid 0.9321 1.0526 0.9825 1.0022 0.9536 1.0846
hexose-6-phosphate 0.7946 1.0565 1.1350 0.9791 1.1269 0.9824
histidine 2 1.0179 0.9280 0.7950 0.8084 1.3120 1.1658
isoleucine 0.9785 1.0153 0.8807 0.8383 1.1840 1.1064
isoleucine minor 0.8453 1.0840 1.1888 0.7368 1.0043 1.1762
leucine 1.0256 0.9435 0.9296 0.9196 1.1367 1.0605
linoleic acid 1.0043 1.1739 0.6826 0.8732 1.1738 1.0030
lysine 1.0365 0.9523 0.8331 0.7383 1.2756 1.1698
maleimide 0.7841 1.5334 0.8008 0.7967 1.0900 0.8361
malic acid 0.9457 1.0123 0.8760 0.8592 1.1186 1.2093
myristic acid 0.9568 1.0737 0.9294 0.9725 0.9280 1.1243
n-acetylgalactosamine 1.0728 1.0281 1.0626 1.0144 0.8686 0.9032
N-acetyl-L-aspartic acid 1 0.7751 0.8160 0.7173 0.6838 1.2907 1.9216
n-methylalanine 0.8889 1.0185 0.8689 0.7758 1.1981 1.2961
octadecanol 0.9582 1.1015 1.0211 1.0373 0.8365 1.0154
ornithine 4TMS 0.9764 0.9408 0.8273 0.7799 1.3781 1.1390
oxoproline 1.0985 0.8850 0.9027 0.8699 1.1091 1.1430
palmitoleic acid 0.8321 0.9946 0.6625 1.2571 1.3769 0.9635
pelargonic acid 0.8984 1.1063 1.1330 0.8633 1.0032 0.9934
phenylalanine 1.0052 0.9856 0.8469 0.8324 1.2131 1.1215
phosphate 1.0855 1.1840 0.9300 0.8825 1.0667 0.7165
phthalate ester 1.3188 1.0852 0.9563 0.8243 0.7308 0.8826
proline 0.8250 1.0338 1.0621 0.9452 1.1049 1.0995
ribitol 0.9650 1.0908 0.7004 0.9327 1.1432 1.1401
salicylic acid 0.9550 1.0616 1.0516 1.0225 0.7491 1.1520
serine 0.8926 1.1599 0.9023 0.8900 1.0074 1.1215
serine minor 0.9279 1.0635 1.0313 0.9331 0.9700 1.0786
shikimic acid 0.9741 1.0665 0.8897 0.8644 1.1078 1.0772
stearic acid 0.9151 1.0414 1.0122 1.0311 0.9828 1.0390
succinic acid 0.9182 1.0039 1.0192 0.8710 1.1445 1.0820
threonine 0.9487 1.0761 0.8912 0.8174 1.0865 1.1676
threonine minor 0.9542 1.1180 0.9921 0.8905 0.9419 1.0672
trans-4-hydroxy-L-proline minor1 0.9548 1.1659 1.1428 0.9158 0.8241 0.9363
tryptophan 0.9573 1.0472 0.8067 0.8109 1.2026 1.1730
tyrosine 1.0284 0.9653 0.8033 0.7935 1.2668 1.1457
udp-n-acetylglucosamine 0.9006 0.9185 0.8936 0.7852 1.2857 1.3068
uracil 0.9240 1.2234 0.8250 0.7749 1.1061 1.0729
urea 2.5753 0.4955 0.6498 0.6022 0.5809 0.5609
uric acid 0.9278 0.9611 0.8338 0.8054 1.2966 1.2310
uridine minor 0.7471 1.4281 0.6528 0.7309 1.4562 0.8973
valine 1.0096 1.0151 0.8589 0.8421 1.1525 1.1095
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Factors:

F1Group:CONTROL | Gender of Pup in Placenta:F
F2Group:CONTROL | Gender of Pup in Placenta:M
F3Group:HIGHDOSE | Gender of Pup in Placenta:F
F4Group:HIGHDOSE | Gender of Pup in Placenta:M
F5Group:LOWDOSE | Gender of Pup in Placenta:F
F6Group:LOWDOSE | Gender of Pup in Placenta:M
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