Data for Timecourse of Amino Acid Metabolites in LNCaP Cell pellets (Study ST000505)
(Analysis AN000774)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 |
|---|---|---|---|---|---|---|---|---|
| 1-Methylhistidine | 0.8337 | 1.0333 | 1.4207 | 0.7750 | 0.2583 | 0.6575 | 0.5871 | 1.5734 |
| 3-Methylhistidine | 1.0792 | 0.6996 | 1.0963 | 0.9555 | 0.9555 | 1.0835 | 1.0110 | 1.1389 |
| Alanine | 0.6538 | 1.3775 | 0.6343 | 1.1935 | 0.6195 | 1.1973 | 0.6651 | 1.5675 |
| allo-Isoleucine | NA | NA | NA | NA | NA | NA | NA | NA |
| alpha-Aminoadipic-acid | 0.3939 | 1.1818 | 0.3939 | 1.7727 | 0.3939 | 1.1818 | 0.3939 | 1.7727 |
| alpha-Amino-N-butyric-acid | 1.0000 | 1.0000 | 1.0000 | NA | NA | NA | NA | 1.0000 |
| Anserine | NA | NA | NA | NA | NA | NA | NA | NA |
| Arginine | 1.2995 | 0.5525 | 1.3381 | 0.5296 | 1.4314 | 0.6582 | 1.3543 | 0.8813 |
| Asparagine | 1.0611 | 0.9447 | 1.0235 | 0.9203 | 0.9768 | 0.9323 | 1.0551 | 1.0408 |
| Aspartic Acid | 1.0119 | 0.9517 | 1.0692 | 0.9521 | 1.0261 | 0.9462 | 1.0222 | 1.0067 |
| beta-Alanine | NA | NA | NA | 1.0000 | NA | NA | NA | NA |
| beta-Aminoisobutyric-acid | NA | NA | NA | NA | NA | NA | NA | NA |
| Carnosine | NA | NA | NA | NA | NA | NA | NA | NA |
| Citrulline | NA | NA | NA | NA | NA | NA | NA | NA |
| Cystathionine 1 | 0.3673 | 1.7166 | 0.3752 | 1.7725 | 0.3633 | 1.8643 | 0.3673 | 1.2874 |
| Cystathionine 2 | NA | NA | NA | NA | NA | NA | NA | NA |
| Cystine | 1.1271 | 0.7770 | 1.2241 | 0.7586 | 1.2231 | 0.7653 | 1.1906 | 0.9284 |
| Ethanolamine | NA | NA | NA | NA | NA | NA | NA | 1.0000 |
| gamma-Amino-N-butyric-acid | NA | NA | NA | NA | NA | NA | NA | NA |
| Glutamic Acid | 0.7442 | 1.3716 | 0.7253 | 1.3516 | 0.7621 | 1.1958 | 0.7663 | 1.0621 |
| Glutamine | 0.4852 | 1.1653 | 0.4741 | 1.7948 | 0.5327 | 1.8772 | 0.5042 | 1.3715 |
| Glycine | 0.7042 | 1.2980 | 0.7126 | 1.2790 | 0.7065 | 1.1960 | 0.6937 | 1.3612 |
| Histidine | 1.0556 | 0.9283 | 0.9677 | 0.8154 | 1.1541 | 0.7419 | 1.2043 | 1.0806 |
| Homocystine | 1.2615 | 0.9894 | 1.1625 | 0.8657 | 1.2367 | 0.8410 | 1.0141 | 0.6678 |
| Hydroxylysine 1 | NA | NA | NA | NA | NA | NA | NA | NA |
| Hydroxylysine 2 | NA | NA | NA | NA | NA | NA | NA | NA |
| Hydroxyproline | 0.9785 | 0.9585 | 1.0019 | 0.9814 | 1.0930 | 1.0282 | 1.0210 | 0.9981 |
| Isoleucine | 1.0538 | 0.9310 | 1.0642 | 0.8864 | 1.0755 | 0.8766 | 1.0704 | 1.0181 |
| Leucine | 1.0953 | 0.8827 | 1.0958 | 0.8082 | 1.1145 | 0.8205 | 1.1077 | 1.0427 |
| Lysine | 1.0811 | 0.8497 | 1.0592 | 0.8071 | 1.0326 | 0.8483 | 1.1693 | 1.0931 |
| Methionine | 1.2172 | 0.6572 | 1.1999 | 0.5167 | 1.2519 | 0.5757 | 1.2831 | 1.2120 |
| Ornithine | 0.3733 | 1.8744 | 0.3596 | 1.9047 | 0.3409 | 1.5321 | 0.3114 | 1.2401 |
| Phenylalanine | 1.0658 | 0.8527 | 1.0677 | 0.7674 | 1.1047 | 0.7837 | 1.1455 | 1.1567 |
| Phosphoethanolamine | NA | 1.0714 | NA | 0.5357 | 0.3571 | 0.7143 | 0.5357 | 2.3214 |
| Proline | 0.9852 | 1.0197 | 0.9466 | 0.9329 | 0.9931 | 0.9090 | 1.0372 | 1.1274 |
| Sarcosine | NA | 0.8235 | NA | 1.6471 | NA | 1.2353 | NA | 0.4118 |
| Serine | 1.3782 | 0.5227 | 1.3629 | 0.3828 | 1.3848 | 0.4666 | 1.3973 | 1.0303 |
| Taurine | 1.1737 | 0.4611 | 1.1737 | 0.6287 | 1.4251 | 0.4192 | 1.5928 | 1.0479 |
| Threonine | 1.0584 | 0.8822 | 1.0697 | 0.7923 | 1.0763 | 0.7940 | 1.1285 | 1.1338 |
| Tryptophan | 1.1839 | 0.2577 | 1.1678 | NA | 1.2725 | 0.0483 | 1.4416 | 1.2886 |
| Tyrosine | 1.0287 | 0.9118 | 1.0920 | 0.8448 | 1.1105 | 0.8528 | 1.0782 | 1.0630 |
| Valine | 1.1102 | 0.8222 | 1.1159 | 0.7475 | 1.1294 | 0.7319 | 1.1456 | 1.1279 |
Factors:
| F1 | Treatment Factor:treated-100 pM R1881 | 13C media incubation time:24 hours |
| F2 | Treatment Factor:treated-100 pM R1881 | 13C media incubation time:72 hours |
| F3 | Treatment Factor:treated-10 nM R1881 | 13C media incubation time:24 hours |
| F4 | Treatment Factor:treated-10 nM R1881 | 13C media incubation time:72 hours |
| F5 | Treatment Factor:treated-1 nM R1881 | 13C media incubation time:24 hours |
| F6 | Treatment Factor:treated-1 nM R1881 | 13C media incubation time:72 hours |
| F7 | Treatment Factor:treated-vehicle (ethanol) | 13C media incubation time:24 hours |
| F8 | Treatment Factor:treated-vehicle (ethanol) | 13C media incubation time:72 hours |
