Data for Investigating TCA concentrations in mice muscle tissue lacking insulin receptors and IGF-1 receptors (Study ST000512)

(Analysis AN000785)

Values for each metabolite have been scaled by dividing by the mean across all factors

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MetaboliteF1F2F3F4F5F6F7F8
cis-Aconitic Acid 0.5211 2.6056 0.6514 0.5211 1.2507 0.7296 1.0423 1.0423
Citrate 0.8419 0.9487 1.0320 0.9126 1.0200 1.1049 0.7410 1.3229
Fumarate 0.9585 0.7136 0.9687 1.1058 0.8406 1.0733 0.8149 1.3780
Glutamate 0.7034 0.7319 1.0002 1.0566 0.8118 0.9302 0.7745 1.7344
Isocitrate 0.9137 0.3632 1.7876 1.5322 0.6628 0.9806 1.2863 0.5070
Ketoglutarate 0.4148 0.9481 0.4148 0.8889 0.6637 0.4741 0.4741 2.6864
Lactate 1.1376 1.2623 1.2737 1.1135 1.2722 0.9848 0.9104 0.3944
Malate 0.9665 0.7215 0.9611 1.0908 0.8409 1.0732 0.8122 1.3865
Oxaloacetate 0.6812 1.2429 1.3624 1.3983 0.6884 0.7171 0.7888 1.2907
Succinate 1.2793 0.5894 1.0817 1.2425 1.1253 1.0529 0.7502 0.9042
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Factors:

F1Group:CD | Genotype:Irlox | Diet:Chow
F2Group:Control | Genotype:IGFR lox | Diet:Chow
F3Group:Control | Genotype:Irlox | Diet:Chow
F4Group:Control | Genotype:IRlox IGFR lox | Diet:Chow
F5Group:HFD | Genotype:Irlox | Diet:High Fat Diet
F6Group:IGFRKO | Genotype:IGFR -/- | Diet:Chow
F7Group:IRKO | Genotype:IR -/- | Diet:Chow
F8Group:MIGIRKO | Genotype:IR -/- IGFR -/- | Diet:Chow
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