Data for Metabolic effects of weight reduction of very low energy diet vs dietary counseling (Study ST000708)
(Analysis AN001100)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 | F5 |
|---|---|---|---|---|---|
| 16:0 LYSO PC (M+CL)- | NA | 1.8406 | 0.2943 | 1.1995 | 0.7325 |
| 18:0 LYSO-PE (M-H)- | NA | 0.4281 | 0.2210 | 0.4700 | 2.2539 |
| 1-METHYLADENOSINE (M+CL)- | NA | 0.8541 | 1.1132 | 0.8795 | 1.2116 |
| 1-METHYLURIC ACID (M-H)- | NA | 0.7305 | 0.6277 | 1.3293 | 1.6036 |
| 1-METHYLXANTHINE (M-H)- | NA | 0.1742 | 0.4761 | 0.5439 | 2.4062 |
| 3-METHYLXANTHINE (M-H)- | NA | 0.6024 | 0.8272 | 1.0179 | 1.4003 |
| 4-NITROPHENOL (M-H)- | NA | 1.0081 | 0.8455 | 1.0736 | 1.0227 |
| 4-PYRIDOXIC ACID (M-H)- | NA | 0.7994 | 0.3850 | 1.0262 | 1.5510 |
| 5^-METHYLTHIOADENOSINE (M+CL)- | NA | 1.1019 | 0.5933 | 0.9422 | 1.3915 |
| 5-VALEROLACTONE (M+HCOO)- | NA | 0.8870 | 1.4482 | 0.9871 | 0.8808 |
| ARACHIDIC ACID (M-H)- | NA | 0.8029 | 0.4726 | 0.7921 | 1.7238 |
| ARACHIDONIC ACID (M-H)- | NA | 0.6012 | 0.7560 | 0.7659 | 1.7291 |
| BEHENIC ACID (M-H)- | NA | 0.9643 | 0.7154 | 0.9049 | 1.2020 |
| BILIVERDIN (M-H)- | NA | 0.7400 | 0.6287 | 0.8938 | 1.4869 |
| CIS-VACCENIC ACID (M-H)- | NA | 0.9604 | 0.5944 | 0.9688 | 1.3346 |
| CITRAMALIC ACID (M-H)- | NA | 1.0515 | 0.7288 | 1.0208 | 1.1205 |
| CITRIC ACID (M-H)- | NA | 0.8986 | 0.9844 | 1.0303 | 1.0646 |
| CORTICOSTERONE (M+CL)- | NA | 0.3326 | 0.7594 | 1.3912 | 1.2944 |
| CORTICOSTERONE (M+HCOO)- | NA | 0.3085 | 0.8578 | 1.2846 | 1.1679 |
| CORTISOL (M+CL)- | NA | 0.8049 | 0.8840 | 1.1572 | 1.0826 |
| CORTISOL (M+HCOO)- | NA | 0.8250 | 0.8905 | 1.1445 | 1.0743 |
| CORTISONE (M+CL)- | NA | 0.9895 | 1.0580 | 1.0112 | 0.9589 |
| DEOXYADENOSINE (M+CL)- | NA | 1.2307 | 0.9612 | 0.8691 | 0.9645 |
| DEOXYCHOLIC ACID (2M-H)- | NA | 1.3290 | 0.4585 | 0.9227 | 1.2411 |
| DEOXYCHOLIC ACID (M+CL)- | NA | 1.0994 | 0.6387 | 0.9103 | 1.2250 |
| DEOXYCHOLIC ACID (M-H)- | NA | 1.0958 | 0.6118 | 1.0056 | 1.1734 |
| EPIBRASSINOLIDE [ISTD] (M+CL)- | NA | 1.0445 | 0.8982 | 0.9909 | 1.0399 |
| EPIBRASSINOLIDE [ISTD] (M+HCOO)- | NA | 1.0561 | 0.8962 | 0.9946 | 1.0278 |
| ERUCIC ACID (M-H)- | NA | 1.1962 | 0.5149 | 0.9633 | 1.0072 |
| GLUCOSE (M+CL)- | NA | 0.6757 | 0.8314 | 1.0389 | 1.3438 |
| HEPTADECANOIC ACID (M-H)- | NA | 0.7971 | 0.7001 | 0.9188 | 1.4502 |
| HYODEOXYCHOLIC ACID (M-H)- | NA | 0.7873 | 0.6208 | 0.8319 | 1.5982 |
| HYPOXANTHINE (M-H)- | NA | 1.1870 | 1.0311 | 0.5102 | 1.2779 |
| IBUPROFEN (M-H)- | NA | NA | NA | 0.8952 | 1.1048 |
| ISOLEUCINE (M-H)- | NA | 1.9766 | 1.0259 | 0.9318 | 0.3929 |
| KYNURENIC ACID (M-H)- | NA | 1.1378 | 0.6645 | 1.0329 | 1.1154 |
| L-[15N]ANTHRANILIC ACID [ISTD] (M-H)- | NA | 1.1280 | 1.0202 | 1.0133 | 0.8666 |
| LIGNOCERIC ACID (M-H)- | NA | 0.8812 | 0.5938 | 0.8426 | 1.6174 |
| L-TRYPTOPHAN-15N2 [ISTD] (M-H)- | NA | 1.0679 | 0.9181 | 1.0111 | 0.9869 |
| MANDELIC ACID (M-H)- | NA | 1.3793 | 0.6359 | 0.9581 | 1.0373 |
| MEVALONIC ACID (M-H)- | NA | 0.7350 | 1.2043 | 0.8477 | 1.3234 |
| N-ACETYL-DL-METHIONINE (M-H)- | NA | 0.6772 | 0.7041 | 0.7735 | 1.4880 |
| OMEPRAZOLE SULFONE (M-H)- | NA | NA | NA | 0.6378 | 1.7244 |
| PHYTANIC ACID (M-H)- | NA | 0.8519 | 0.8620 | 1.0597 | 1.1868 |
| S-ADENOSYL-L-HOMOCYSTEINE (M-H)- | NA | 1.1033 | 1.7298 | 0.6486 | 0.8008 |
| THEOPHYLLINE (M-H)- | NA | 1.2306 | 0.8777 | 1.2077 | 0.6817 |
| URACIL 5-CARBOXYLIC ACID (M-H)- | NA | 1.2327 | 0.8211 | 1.0097 | 0.9156 |
| URIC ACID (M-H)- | NA | 1.1458 | 1.2725 | 0.9182 | 0.7786 |
| URIDINE (M+CL)- | NA | 1.1053 | 1.0333 | 0.9495 | 0.9406 |
| URSODIOL (M-H)- | NA | 0.4557 | 0.6243 | 0.8046 | 1.8995 |
Factors:
| F1 | GROUP:POOLED | VISIT:POOLED |
| F2 | GROUP:Standard | VISIT:visit 1 |
| F3 | GROUP:Standard | VISIT:visit 2 |
| F4 | GROUP:VLED | VISIT:visit 1 |
| F5 | GROUP:VLED | VISIT:visit 2 |
