Data for Age and exercise effect on metabolomics in rats (Study ST000759)
(Analysis AN001194)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 | F10 |
|---|---|---|---|---|---|---|---|---|---|---|
| 16:0 LYSO PC (M+CL)- | 0.7932 | 0.9561 | 0.6999 | 0.6767 | 0.8799 | 1.0479 | 1.2214 | 1.1805 | 1.1137 | 1.1821 |
| 16:0 LYSO PC (M+HCOO)- | 0.7345 | 0.9171 | 0.7736 | 0.6853 | 0.8667 | 0.9671 | 1.3920 | 1.1689 | 1.0511 | 1.1852 |
| 18:0 LYSO-PE (M-H)- | 0.6332 | 0.6583 | 0.5259 | 0.4146 | 0.7282 | 0.9428 | 1.3221 | 1.1209 | 1.0433 | 1.9856 |
| 2-DEOXY-D-GLUCOSE (M+CL)- | 1.0115 | 1.1708 | 1.3216 | 1.0357 | 0.3833 | 0.1571 | 2.4125 | 1.5478 | 0.2049 | 0.5781 |
| 2-HYDROXY-3-METHYLBUTYRIC ACID (M-H)- | 0.9179 | 0.5640 | 0.8423 | 0.6598 | 1.3034 | 2.4686 | 0.4957 | 0.6736 | 1.0084 | 1.1798 |
| 2-HYDROXYBUTYRIC ACID (M-H)- | 0.8493 | 1.1185 | 1.0604 | 0.8269 | 0.7551 | 1.2507 | 0.8207 | 0.8685 | 0.7780 | 1.5737 |
| 3-(2-HYDROXYPHENYL)PROPANOIC ACID (M-H)- | 0.9985 | 0.5194 | 0.9533 | 0.5587 | 2.0054 | 1.1710 | 0.8591 | 0.9085 | 0.7890 | 0.8943 |
| 3-HYDROXY-3-METHYLGLUTARIC ACID (M-H)- | 0.2861 | 0.4100 | 0.5117 | 0.3822 | 1.2763 | 0.8060 | 1.0263 | 0.9767 | 1.9146 | 1.6347 |
| 4-COUMARIC ACID (M-H)- | 2.2185 | 1.5973 | 1.4108 | 1.0545 | 1.7732 | 1.4660 | 0.4647 | 0.3092 | 0.3158 | 0.3590 |
| 4-HYDROXYBENZOIC ACID (M-H)- | 0.7166 | 0.9028 | 0.9088 | 0.7777 | 1.1804 | 1.1979 | NA | 0.5175 | 1.1229 | 1.2169 |
| 4-NITROPHENOL (M-H)- | 1.0542 | 0.9639 | 1.0474 | 1.1030 | 0.9853 | 1.0534 | 0.8086 | 0.9104 | 1.0509 | 1.0452 |
| 4-PYRIDOXIC ACID (M-H)- | 0.3938 | 0.2598 | 0.2478 | 0.1564 | 1.0483 | 0.6519 | 0.9589 | 1.1189 | 2.5451 | 1.5594 |
| 5^-METHYLTHIOADENOSINE (M+CL)- | 0.4969 | 0.4576 | 0.4847 | 0.4608 | 0.8293 | 0.9014 | 0.6993 | 0.6299 | 2.3552 | 1.7669 |
| 5-VALEROLACTONE (M+HCOO)- | 1.0800 | 0.2118 | NA | NA | 0.9125 | 0.8374 | 0.4174 | 0.4803 | 1.3227 | 1.8808 |
| ADENOSINE 5^-MONOPHOSPHATE (M-H)- | NA | NA | NA | NA | 0.5578 | 0.5375 | NA | NA | 1.2579 | 1.4801 |
| ADENOSINE (M+CL)- | 0.0194 | 0.0521 | 0.0285 | 0.0401 | 0.7172 | 0.4373 | 2.7412 | 2.3157 | 2.3824 | 1.9879 |
| ADIPIC ACID (M-H)- | 1.0470 | 1.0559 | 1.0585 | 1.2394 | 0.2561 | 0.3656 | 0.3363 | 0.4349 | 2.3928 | 1.2827 |
| ALLANTOIN (M-H)- | 1.5593 | 1.3721 | 1.8967 | 1.8489 | 0.4708 | 0.5651 | 0.5798 | 0.2218 | 0.6799 | 0.7868 |
| ARACHIDIC ACID (M-H)- | 0.4303 | 0.6768 | 0.6643 | 0.6789 | 0.7158 | 0.5815 | 1.8796 | 1.3843 | 0.7371 | 1.0488 |
| ARACHIDONIC ACID (M-H)- | 0.4803 | 0.8943 | 0.6533 | 0.6222 | 0.6694 | 0.7659 | 1.6085 | 0.9440 | 1.3803 | 1.4357 |
| AZELAIC ACID (M-H)- | 1.2014 | 0.9422 | 0.9253 | 0.8916 | 1.1104 | 1.0972 | 0.5252 | 0.4628 | 1.3392 | 1.3922 |
| BEHENIC ACID (M-H)- | 0.5433 | 0.8184 | 0.8520 | 0.5219 | 0.5055 | 0.5454 | 1.9770 | 1.2475 | 0.6819 | 0.9778 |
| BENZOIC ACID (M-H)- | 0.9913 | 1.2890 | 1.0399 | 1.0266 | 1.1820 | 1.0531 | 0.6481 | 0.7441 | 1.0522 | 1.0662 |
| CHOLIC ACID (2M-H)- | 0.4902 | 0.4944 | 0.3829 | 0.2175 | 0.3448 | 0.5318 | 0.6797 | 1.5673 | 1.3819 | 2.7712 |
| CHOLIC ACID (M-H)- | 1.0837 | 1.4238 | 0.6526 | 0.5477 | 0.4612 | 0.6062 | 0.5138 | 0.8151 | 2.2078 | 1.1680 |
| CIS-11-EICOSENOIC ACID (M-H)- | 0.4598 | 0.8459 | 0.7273 | 0.7647 | 0.4485 | 0.8492 | 1.7454 | 1.2734 | 1.0444 | 1.3762 |
| CIS-ACONITIC ACID (M-H)- | 0.2959 | 0.0446 | NA | NA | 2.5529 | 2.7581 | 0.2081 | 0.3189 | 0.8350 | 0.6965 |
| CITRAMALIC ACID (M-H)- | 0.8196 | 0.2427 | 0.3338 | 0.1821 | 1.2774 | 1.3415 | 0.6001 | 1.0667 | 1.5524 | 1.2563 |
| CITRIC ACID (M-H)- | 0.1227 | 0.0247 | 0.0287 | 0.0146 | 2.1629 | 2.0884 | 0.1233 | 0.1844 | 2.1131 | 2.3358 |
| CORTICOSTERONE (M+CL)- | 0.2599 | 0.6702 | 0.9229 | 0.5093 | 1.7275 | 1.4217 | 1.4659 | 0.9420 | 1.2135 | 0.7722 |
| CORTICOSTERONE (M+HCOO)- | 0.2110 | 0.5199 | 0.7072 | 0.4226 | 2.0026 | 1.8346 | 1.0372 | 0.6963 | 1.4971 | 0.9265 |
| DEHYDROASCORBIC ACID (M-H)- | 0.1431 | 0.0019 | NA | NA | 1.3316 | 1.3103 | 0.0849 | 0.1042 | 1.7129 | 1.6773 |
| DEOXYCHOLIC ACID (2M-H)- | 0.8888 | 0.5245 | 0.2640 | 0.1537 | 0.2459 | 1.0947 | 0.4108 | 1.5465 | 1.2782 | 1.7582 |
| DEOXYCHOLIC ACID (M-H)- | 0.3830 | 0.3387 | 0.4555 | 0.3685 | 0.6716 | 0.6496 | 0.7910 | 1.5646 | 1.5815 | 1.8297 |
| DEOXYURIDINE (M+CL)- | 0.8378 | 0.9333 | 0.7268 | 0.6591 | 0.7725 | 1.5585 | 0.8510 | 1.2157 | 1.1078 | 1.1779 |
| DOCOSAHEXAENOIC ACID (M-H)- | 0.6753 | 1.2303 | 0.9725 | 0.8676 | 0.7062 | 0.8494 | 0.7032 | 0.6417 | 1.3337 | 1.6780 |
| EDTA (M-H)- | NA | NA | NA | NA | 1.6662 | 0.8433 | NA | NA | 0.6389 | 0.9352 |
| ERUCIC ACID (M-H)- | 0.3896 | 0.6004 | 0.4038 | 0.5104 | 0.4655 | 0.6710 | 2.0563 | 1.5053 | 0.7744 | 1.1062 |
| ETHYLMALONIC ACID (M-H)- | 0.8411 | 0.3153 | 0.4455 | 0.3853 | 0.7450 | 0.8602 | 0.6886 | 1.2663 | 1.7283 | 1.2217 |
| GLUCOSE (M+CL)- | 0.8239 | 1.1578 | 1.2278 | 1.7030 | 0.2214 | 0.1449 | 2.4751 | 1.8530 | 0.1485 | 0.2706 |
| GLUTARIC ACID (M-H)- | 1.2152 | 1.3066 | 0.9073 | 0.8423 | 0.7547 | 0.8743 | 0.7567 | 0.5457 | 2.1485 | 0.4975 |
| GLYCERIC ACID (M-H)- | 0.7379 | 1.6201 | 0.8760 | 1.6948 | 0.6588 | 0.5433 | 1.4075 | 1.2378 | 0.5994 | 0.6395 |
| GLYCOCHOLIC ACID (M-H)- | 0.8837 | 0.3568 | 0.6472 | 0.5696 | 0.4747 | 0.4336 | 0.5262 | 0.2408 | 1.8818 | 2.9018 |
| HEPTADECANOIC ACID (M-H)- | 0.6188 | 0.9622 | 0.9311 | 0.9630 | 0.5316 | 0.8069 | 1.4644 | 0.9067 | 1.0008 | 1.4809 |
| HIPPURIC ACID (M-H)- | 1.1836 | 1.1040 | 0.8529 | 0.5614 | 0.9917 | 0.6389 | 1.5198 | 1.8285 | 0.5334 | 0.7879 |
| HYODEOXYCHOLIC ACID (M-H)- | 0.9040 | 1.1927 | 1.0461 | 1.0879 | 0.6515 | 1.1405 | 0.9314 | 0.8448 | 1.1836 | 0.9877 |
| INDOLE-3-ACETIC ACID (M-H)- | 0.8338 | 0.4761 | 0.7576 | 0.4640 | 1.0965 | 1.1770 | 1.0146 | 1.3455 | 1.2114 | 1.0574 |
| INOSINE (M-H)- | 0.0664 | NA | NA | NA | 0.4072 | 0.6754 | 1.1943 | 1.8332 | 0.5436 | 0.5548 |
| KYNURENIC ACID (M-H)- | 1.7815 | 0.7638 | 0.4871 | NA | 1.9107 | 1.0611 | 0.6522 | 0.8161 | 0.9066 | 0.9447 |
| L-[15N]ANTHRANILIC ACID [ISTD] (M-H)- | 1.0025 | 1.0773 | 1.1083 | 1.1610 | 1.0763 | 0.8958 | 0.9102 | 0.8571 | 1.0262 | 0.9685 |
| LEUCINE (M-H)- | 0.9475 | 0.6412 | 1.0519 | 0.7343 | 1.1119 | 1.2618 | 1.4277 | 2.1760 | 0.5240 | 0.5033 |
| LEUKOTRIENE B4 (M-H)- | NA | NA | NA | NA | NA | NA | 0.3076 | NA | 1.0136 | 1.3259 |
| LIGNOCERIC ACID (M-H)- | 0.6124 | 0.8145 | 0.6277 | 0.7363 | 0.4651 | 0.6314 | 2.5755 | 1.6072 | 0.7033 | 0.8861 |
| LINOLEIC ACID (M-H)- | 0.7396 | 1.5186 | 1.2351 | 1.1234 | 0.5989 | 0.8717 | 1.0501 | 0.5871 | 0.9656 | 1.2784 |
| L-TRYPTOPHAN-15N2 [ISTD] (M-H)- | 1.0604 | 1.1180 | 1.1988 | 1.2098 | 0.9740 | 0.9734 | 0.9157 | 0.9484 | 0.8807 | 0.8762 |
| MALEIC ACID (M-H)- | 1.2430 | 1.1156 | 1.1017 | 0.9776 | 1.3456 | 0.9690 | 0.9588 | 0.8374 | 0.8778 | 0.7485 |
| MALIC ACID (M-H)- | 0.3208 | 0.0756 | 0.2266 | 0.2181 | 2.0352 | 2.0473 | 0.5822 | 0.5119 | 1.6049 | 1.3174 |
| MALIC ACID (M-H)+[-H2O] | 1.0925 | 0.5711 | 0.9214 | 0.3802 | 1.4448 | 1.4005 | 0.8151 | 0.7958 | 1.3600 | 0.8303 |
| MANDELIC ACID #2 (M-H)- | 1.1941 | 0.1860 | NA | NA | 0.6509 | 0.8223 | 1.1549 | 0.6153 | 1.2472 | 1.2918 |
| MANDELIC ACID (M-H)- | 1.0436 | NA | 0.4447 | NA | 0.9049 | 0.9337 | 0.4021 | 0.6144 | 1.4757 | 1.4379 |
| METHYLMALONIC ACID (M-H)- | 0.4564 | 0.3762 | 0.2763 | 0.1971 | 0.4526 | 0.6285 | 1.1064 | 1.6195 | 1.8430 | 1.8269 |
| MEVALONIC ACID (M-H)- | 1.1212 | 1.4517 | 1.5219 | 1.3272 | NA | 0.8208 | 0.7956 | 0.6783 | 0.8836 | 0.6665 |
| MYRISTIC ACID (M-H)- | 0.4385 | 0.5914 | 0.6641 | 0.6045 | 0.4416 | 0.5473 | 0.8663 | 0.5383 | 1.6360 | 2.6685 |
| MYRISTOLEIC ACID (M-H)- | 0.4171 | 1.0599 | 0.6215 | 0.8046 | 0.6490 | 0.8815 | 0.8966 | 0.5647 | 1.5724 | 1.7897 |
| N-ACETYL-D-GLUCOSAMINE (M+CL)- | 0.5728 | 2.0623 | 1.9873 | NA | 0.2143 | 0.2308 | 1.6290 | 1.4226 | 0.2802 | 0.4888 |
| N-ACETYL-L-LEUCINE (M-H)- | 1.4738 | 0.6114 | 0.6824 | 0.3658 | 1.2918 | 1.4574 | 0.7766 | 1.1588 | 1.4238 | 0.7603 |
| NERVONIC ACID (M-H)- | 0.3888 | 0.5702 | 0.3587 | 0.4801 | 0.3424 | 0.7302 | 2.8937 | 1.8843 | 0.7793 | 0.9919 |
| OLEOYL-GLYCEROL (M+HCOO)- | 0.9229 | 2.5534 | 2.5420 | 1.1670 | 0.6735 | 0.7591 | 0.4136 | 0.3155 | 0.3848 | 0.5929 |
| OMEGA-HYDROXYDODECANOIC ACID (M-H)- | NA | NA | NA | NA | NA | NA | NA | NA | 0.8325 | 1.1675 |
| PALMITIC ACID (M-H)- | 0.5320 | 0.9658 | 1.0459 | 1.0235 | 0.5315 | 0.6772 | 1.2675 | 0.6000 | 1.2456 | 1.6809 |
| PALMITOLEIC ACID (M-H)- | 0.7551 | 2.0886 | 1.2474 | 1.5069 | 0.3603 | 0.5207 | 0.9249 | 0.3669 | 0.7680 | 1.5028 |
| PANTOTHENIC ACID (M+CL)- | 0.6643 | 0.2533 | NA | NA | 0.9467 | 0.9779 | 0.5200 | 1.0063 | 1.0017 | 1.6248 |
| PANTOTHENIC ACID (M-H)- | 0.5626 | 0.5196 | 0.3772 | 0.2998 | 0.8785 | 1.2199 | 0.7029 | 0.9576 | 1.4325 | 2.2787 |
| PHENYLALANINE (M-H)- | 0.9767 | 0.6163 | 0.8279 | 0.6506 | 0.8822 | 1.3945 | 1.2666 | 1.3820 | 0.9702 | 0.9238 |
| PIMELIC ACID (M-H)- | NA | 0.5929 | 0.5266 | NA | 0.6960 | NA | 0.3386 | NA | 1.6203 | 0.9851 |
| PYRUVIC ACID (M-H)- | 0.6605 | 1.3131 | 1.4195 | 1.6104 | 0.3505 | 0.8038 | NA | NA | 1.5646 | 0.7512 |
| SALICYLATE #2 (M-H)- | 1.2823 | 1.0804 | 1.3844 | 0.8330 | 1.6844 | 1.2296 | 1.1961 | 1.3573 | 0.2004 | 0.3423 |
| SEBACIC ACID (M-H)- | 0.1762 | 0.1197 | 0.1505 | 0.1454 | 0.2220 | 0.2258 | 0.1330 | 0.1189 | 2.4166 | 2.7699 |
| STEARIC ACID (M-H)- | 0.5368 | 0.6097 | 0.3079 | 0.4540 | 0.5107 | 0.7424 | 2.7966 | 1.9949 | 0.5173 | 1.0489 |
| SUBERIC ACID (M-H)- | 0.7555 | 0.5339 | 0.6479 | 0.5498 | 0.6996 | 0.6984 | 0.5625 | 0.9231 | 1.7707 | 1.6747 |
| SUCCINIC ACID (M-H)- | 0.8272 | 1.1836 | 0.9366 | 1.2421 | 0.3733 | 0.3703 | 1.3395 | 1.1401 | 1.9125 | 0.3991 |
| THYMIDINE (M+CL)- | 0.5350 | 0.4606 | 0.3998 | 0.3158 | 1.1880 | 1.0841 | 0.7224 | 0.7075 | 2.3231 | 1.4964 |
| THYMIDINE (M+HCOO)- | 0.7962 | 0.9476 | 0.8518 | 0.7809 | 0.8204 | 1.0383 | 1.0161 | 1.0218 | 1.3080 | 1.1703 |
| TRANS-ACONITIC ACID (M-H)- | 0.1268 | 0.0747 | 0.0614 | 0.0473 | 1.6850 | 1.6017 | 0.2351 | 0.2603 | 2.3166 | 2.1886 |
| TRANS-VACCENIC ACID (M-H)- | 0.6052 | 1.5931 | 1.1720 | 1.1661 | 0.4632 | 0.6990 | 1.1558 | 0.4677 | 0.9753 | 1.5395 |
| TRICARBALLYLIC ACID (M-H)- | 0.1807 | 0.0366 | 0.0175 | 0.0258 | 1.0380 | 0.9806 | 0.2189 | 0.2300 | 2.5765 | 1.7877 |
| TRICARBALLYLIC ACID (M-H)-[-H2O] | 0.1678 | 0.2067 | 0.1269 | 0.1297 | 0.6737 | 0.6421 | 0.1278 | 0.1626 | 2.5569 | 1.3146 |
| TRICOSANOIC ACID (M-H)- | 0.6229 | 0.7878 | 0.7774 | 0.7503 | 0.5133 | 0.6402 | 1.8146 | 1.4498 | 0.7591 | 0.8059 |
| TRYPTOPHAN (M-H)- | 1.0368 | 0.9472 | 0.9829 | 0.7994 | 1.1272 | 1.1540 | 1.2508 | 1.2754 | 0.7133 | 0.8166 |
| TYROSINE (M-H)- | 1.2142 | 0.7408 | 0.7443 | 0.7637 | 1.0077 | 1.4025 | 1.0570 | 1.4309 | 0.6613 | 1.0167 |
| URIC ACID (M-H)- | 0.7053 | 0.8292 | 0.9424 | 0.8852 | 0.7247 | 0.5166 | 2.1255 | 2.0712 | 0.5732 | 0.5272 |
| URIDINE (M+CL)- | 0.6510 | 0.8023 | 0.7959 | 0.6930 | 0.4712 | 0.5486 | 1.7482 | 2.0188 | 1.0361 | 0.8500 |
| URIDINE (M-H)- | 0.6242 | 0.7669 | 0.8310 | 0.7588 | 0.6041 | 1.5129 | 1.2556 | 1.8249 | 0.8140 | 0.7821 |
| URSODIOL (M+HCOO)- | 0.3585 | 0.3546 | 0.2324 | 0.4110 | 0.3347 | 1.1301 | 0.6124 | 1.0274 | 3.1459 | 1.2734 |
| XANTHOSINE (M-H)- | NA | NA | NA | NA | 0.1175 | NA | 0.1560 | NA | 1.7083 | 0.3692 |
| ZEATIN [ISTD] (M+CL)- | 0.7403 | 0.7649 | 0.8194 | 0.7446 | 1.1711 | 1.2684 | 0.9266 | 0.8776 | 1.2388 | 1.2519 |
| ZEATIN [ISTD] (M-H)- | 0.8121 | 0.8585 | 0.9126 | 0.8479 | 1.1045 | 1.2258 | 0.9898 | 0.9219 | 1.0955 | 1.1371 |
Factors:
| F1 | Age:106 week | Line:HRT | Sex:Female | Training:no |
| F2 | Age:106 week | Line:HRT | Sex:Female | Training:yes |
| F3 | Age:106 week | Line:LRT | Sex:Female | Training:no |
| F4 | Age:106 week | Line:LRT | Sex:Female | Training:yes |
| F5 | Age:126 week | Line:HCR | Sex:Male | Training:no |
| F6 | Age:126 week | Line:LCR | Sex:Male | Training:no |
| F7 | Age:14 week | Line:HCR | Sex:Male | Training:no |
| F8 | Age:14 week | Line:LCR | Sex:Male | Training:no |
| F9 | Age:4 week | Line:HCR | Sex:Male | Training:no |
| F10 | Age:4 week | Line:LCR | Sex:Male | Training:no |
