Data for Insights into myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) phenotypes through comprehensive metabolomics (part III)) (Study ST000802)
(Analysis AN001274)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 |
|---|---|---|---|---|---|---|---|---|
| 10_11-DHHep | NA | NA | NA | NA | NA | NA | NA | NA |
| 10-Nitrolinoleate | NA | NA | NA | NA | NA | NA | NA | NA |
| 10-Nitrooleate | NA | 0.5032 | NA | NA | NA | 1.2484 | NA | NA |
| 11,12-DiHETrE | 0.8928 | 1.1377 | 1.0087 | 1.1230 | 0.9728 | 0.9295 | 0.9539 | 0.9696 |
| 11(12)-EpETE | 1.0000 | NA | NA | NA | NA | NA | NA | NA |
| 11,12-EpETrE | 1.1216 | 0.9017 | 0.8577 | 1.0185 | 1.1732 | 0.9017 | 0.9787 | 0.9897 |
| 11-HETE | 0.7543 | 1.0697 | 0.3320 | 0.5802 | 0.7335 | 1.1595 | 3.7411 | 0.8349 |
| 12,13-DiHODE | 0.9623 | 1.4453 | NA | 0.4022 | 0.7209 | 0.8630 | NA | 2.8562 |
| 12_13-DiHOME | 0.8000 | 1.1200 | NA | 0.8000 | 1.2000 | 1.0667 | 0.8000 | 0.8000 |
| 12(13)Ep-9-KODE | 0.4901 | 1.3129 | 0.5331 | 0.3625 | 0.7679 | 0.9520 | 2.5115 | 1.9386 |
| 12(13)-EpOME | 0.6225 | 1.2025 | 0.2663 | 1.0315 | 1.1198 | 0.9669 | 1.2286 | 1.0181 |
| 12S-HEPE | 0.6930 | 1.0519 | 0.2565 | 0.9682 | 1.2082 | 1.2186 | 0.6945 | 0.5173 |
| 12S-HETE | 0.8819 | 1.1319 | 0.6358 | 0.7154 | 0.9918 | 1.0900 | 0.9923 | 0.9144 |
| 13-HOTE | 0.6149 | 1.3493 | 0.2190 | 0.9146 | 0.6896 | 1.0524 | 2.3420 | 0.9367 |
| 13-KODE | 0.3382 | 1.1175 | 0.1824 | 0.2380 | 0.4924 | 1.0332 | 4.5477 | 3.0893 |
| 13S-HODE | 0.4738 | 1.2070 | 0.2447 | 0.5900 | 0.7028 | 1.0162 | 3.8462 | 1.6896 |
| 14,15-DiHETE | 0.7923 | 1.0694 | 0.4579 | 1.1813 | 0.8694 | 1.2186 | 0.9992 | 0.6210 |
| 14,15-DiHETrE | 0.9347 | 1.1094 | 0.9778 | 1.0873 | 0.9802 | 0.9634 | 0.8895 | 0.8929 |
| 14(15)-EpETE | NA | NA | NA | NA | NA | NA | NA | NA |
| 14,15-EpETrE | NA | NA | NA | NA | NA | NA | NA | NA |
| 14-HDoHE | 0.9343 | 1.3166 | 0.3472 | 0.5610 | 1.0850 | 1.0206 | 0.4962 | 0.5427 |
| 15,16-DiHODE | 0.8997 | 0.9575 | 0.2967 | 1.5415 | 0.8113 | 1.1450 | 0.8772 | 0.8654 |
| 15,16-EpODE | 0.5557 | 1.1124 | 0.0730 | 0.9341 | 0.6818 | 1.3803 | 4.3548 | 0.2118 |
| 15-deoxy PGJ2 | 0.8837 | 0.9879 | 0.9390 | 0.9194 | 0.9482 | 1.0547 | 1.3172 | 1.2650 |
| 15-HEPE | 0.8809 | 1.1372 | 0.2445 | 1.1998 | 0.7462 | 1.1710 | 1.3284 | 0.4570 |
| 15-HETE | 0.8887 | 1.1237 | 0.5533 | 0.8182 | 0.8768 | 1.0460 | 1.6780 | 0.9637 |
| 15-KETE | NA | NA | NA | NA | NA | NA | NA | NA |
| 15-Keto PGE2 | NA | NA | NA | NA | NA | NA | NA | NA |
| 16(17)-EpDPE | NA | NA | NA | NA | NA | NA | NA | NA |
| 17,18-DiHETE | 0.8064 | 1.0533 | 0.4821 | 1.2885 | 0.8478 | 1.1948 | 0.9593 | 0.7089 |
| 17(18)-EpETE | 0.6703 | 1.3791 | NA | NA | 0.6269 | 1.1776 | 1.5190 | 0.5642 |
| 17-HDoHE | 0.9747 | 1.1355 | 0.2968 | 0.9224 | 0.9232 | 1.0232 | 1.5909 | 0.5797 |
| 19,20-DiHDPE | 1.0047 | 1.2180 | 0.4175 | 1.1527 | 0.8651 | 0.9796 | 0.7691 | 0.5872 |
| 19(20)-EpDPE | NA | NA | NA | NA | NA | NA | NA | NA |
| 20-HETE | NA | NA | NA | NA | NA | NA | NA | NA |
| 4-HDoHE | 1.0295 | 1.1462 | 0.2764 | 1.0032 | 0.9651 | 0.9437 | 1.3969 | 0.5739 |
| 5,6-DiHETrE | 0.8613 | 1.2202 | 0.3276 | 1.1687 | 0.8494 | 0.9850 | 0.8989 | 0.9367 |
| 5-HETE | 0.9081 | 1.1127 | 0.4891 | 0.8186 | 0.8916 | 0.9766 | 2.2798 | 0.8973 |
| 5-KETE | 1.0419 | 0.9934 | 0.5321 | 0.6034 | 0.8608 | 1.0888 | 2.5276 | 0.7903 |
| 5S,15R-diHETE | 0.6454 | 1.0344 | NA | 1.1915 | 0.4965 | 0.8979 | 3.0085 | 1.9957 |
| 5S-HEPE | 1.0150 | 1.1463 | 0.3245 | 1.3781 | 0.7740 | 1.0705 | 0.5934 | 0.5424 |
| 6-keto-PGF1alpha | NA | NA | NA | NA | NA | 1.0000 | NA | NA |
| 6-trans-LTB4 | 0.8186 | 1.2106 | 0.4559 | 0.5518 | 1.0133 | 0.9887 | 2.0473 | 0.8437 |
| 8,15-DiHETE | 0.3377 | 1.1110 | 0.1292 | 0.8434 | 0.4796 | 1.0627 | 4.6275 | 1.6616 |
| 8,9-DiHETrE | 1.0105 | 1.1106 | 0.7145 | 1.1455 | 0.7785 | 0.9993 | 1.0769 | 0.9734 |
| 8(9)-EpETrE | NA | NA | NA | NA | NA | NA | NA | NA |
| 8S-HETE | 0.8540 | 1.1291 | 0.4719 | 0.7886 | 0.8595 | 1.0241 | 2.3096 | 0.9139 |
| 9,10-DiHODE | 0.6170 | 1.5695 | 0.0840 | 1.2656 | 0.7172 | 0.7388 | 0.7556 | 1.0410 |
| 9,10-DiHOME | 0.5355 | 1.2175 | 0.2844 | 1.5102 | 0.7287 | 1.0746 | 1.0723 | 1.3195 |
| 9,10-e-DiHO | 0.7220 | 1.1750 | 1.2384 | 1.2187 | 0.8985 | 1.0006 | 0.8734 | 1.1046 |
| 9,10-EpO | 0.6366 | 0.9906 | 1.2720 | 1.4832 | 0.8872 | 0.9262 | 2.1822 | 1.4016 |
| 9(10)-EpOME | 0.6019 | 1.1956 | 0.3635 | 0.8360 | 0.9987 | 0.9395 | 2.0407 | 1.3293 |
| 9,12,13-TriHOME | 0.6788 | 1.1198 | 0.7735 | 1.1179 | 0.8919 | 0.9658 | 1.8913 | 1.3087 |
| 9-HEPE | 0.9705 | 1.1509 | 0.2877 | 1.3000 | 0.7562 | 1.1168 | 0.8076 | 0.5188 |
| 9-HETE | 0.7578 | 1.0684 | 0.4174 | 0.6317 | 0.7754 | 1.1384 | 3.5466 | 0.8103 |
| 9-HODE | 0.4822 | 1.1817 | 0.2404 | 0.5908 | 0.6870 | 1.0256 | 3.9743 | 1.7099 |
| 9-HOTE | 0.7640 | 1.3473 | 0.2654 | 1.4613 | 0.8175 | 0.9118 | 1.0776 | 0.6180 |
| 9-KODE | 0.3240 | 1.1229 | 0.1565 | 0.2225 | 0.5052 | 1.0977 | 3.9082 | 3.1583 |
| 9-Nitrooleate | NA | NA | NA | NA | NA | NA | NA | NA |
| alpha-12(13)-EpODE | 0.5395 | 1.3347 | 0.2516 | 1.1622 | 0.9882 | 1.0359 | 1.0826 | 0.7224 |
| Alpha-9(10)-EpODE | 0.5142 | 1.1728 | 0.1232 | 0.3373 | 0.6405 | 1.1735 | 3.9296 | 1.4708 |
| CUDA | NA | NA | NA | NA | NA | NA | NA | NA |
| d11-14,15-DiHETrE | NA | NA | NA | NA | NA | NA | NA | NA |
| d17-10-Nitrooleate | NA | NA | NA | NA | NA | NA | NA | NA |
| d4-12(13)-EpOME | NA | NA | NA | NA | NA | NA | NA | NA |
| d4 6-keto PGF1a | NA | NA | NA | NA | NA | NA | NA | NA |
| d4-9(S)-HODE | NA | NA | NA | NA | NA | NA | NA | NA |
| d4-LTB4 | NA | NA | NA | NA | NA | NA | NA | NA |
| d4-PGD2 | NA | NA | NA | NA | NA | NA | NA | NA |
| d4-PGF2a | NA | NA | NA | NA | NA | NA | NA | NA |
| d4-TXB2 | NA | NA | NA | NA | NA | NA | NA | NA |
| d6-20-HETE | NA | NA | NA | NA | NA | NA | NA | NA |
| d8-12(S)-HETE | NA | NA | NA | NA | NA | NA | NA | NA |
| d8-5(S)-HETE | NA | NA | NA | NA | NA | NA | NA | NA |
| Lipoxin A4 | NA | 0.6452 | NA | NA | NA | 1.3364 | 0.8410 | NA |
| LTB4 | 0.6150 | 1.0583 | NA | 0.3289 | 0.7341 | 0.9312 | 3.1177 | 0.4719 |
| LTB5 | NA | NA | NA | NA | NA | NA | NA | NA |
| PGD2 | 0.8330 | 1.2390 | NA | 0.5171 | 0.5863 | 1.0140 | 2.4315 | 0.6024 |
| PGE1 | 0.8448 | 0.9483 | 0.8720 | 0.9810 | 1.0900 | 0.9810 | 2.0166 | 0.7630 |
| PGE2 | NA | NA | NA | NA | NA | NA | NA | NA |
| PGE3 | NA | NA | NA | NA | NA | NA | NA | NA |
| PGF2alpha | 0.7084 | 0.9050 | 0.3317 | 1.2043 | 0.8753 | 1.1730 | 1.3028 | 1.6413 |
| PGF3alpha | NA | NA | NA | NA | NA | NA | NA | NA |
| PHAU | NA | NA | NA | NA | NA | NA | NA | NA |
| Resolvin D1 | NA | NA | NA | NA | NA | NA | NA | NA |
| TXB2 | 0.8700 | 1.1671 | NA | 0.5928 | 0.7873 | 1.0374 | 1.3199 | 1.5783 |
Factors:
| F1 | CaseStatus:Case | SEX:Female | AGE_DICH:20_50 |
| F2 | CaseStatus:Case | SEX:Female | AGE_DICH:over50 |
| F3 | CaseStatus:Case | SEX:Male | AGE_DICH:20_50 |
| F4 | CaseStatus:Case | SEX:Male | AGE_DICH:over50 |
| F5 | CaseStatus:Control | SEX:Female | AGE_DICH:20_50 |
| F6 | CaseStatus:Control | SEX:Female | AGE_DICH:over50 |
| F7 | CaseStatus:Control | SEX:Male | AGE_DICH:20_50 |
| F8 | CaseStatus:Control | SEX:Male | AGE_DICH:over50 |
