Data for Statin Immuno-Metabolomics in Asthma (part IV) (Study ST000846)
(Analysis AN001369)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 | F5 | F6 |
|---|---|---|---|---|---|---|
| 10-Nitrooleate | 0.8746 | 0.9291 | 0.9804 | 1.3177 | 0.7515 | 1.1468 |
| 11_12-DiHETrE | 1.0796 | 1.4014 | 1.0484 | 1.0536 | 0.6436 | 0.7734 |
| 11(12)-EpETE | NA | NA | NA | NA | NA | NA |
| 11(12)-EpETrE | 1.2551 | 0.9270 | 1.3815 | 0.8006 | 0.9451 | 0.6907 |
| 11-HETE | 1.7475 | 0.8064 | 1.4730 | 0.6077 | 0.5848 | 0.7806 |
| 12_13-DiHODE | NA | NA | NA | NA | NA | NA |
| 12_13-DiHOME | 0.6530 | 1.1189 | 1.0008 | 1.0925 | 0.6919 | 1.4429 |
| 12(13)-Ep-9-KODE | 0.7007 | 0.9168 | 0.7720 | 0.8882 | 0.7470 | 1.9753 |
| 12(13)-EpODE | 0.6443 | 1.6268 | 0.7007 | 1.5060 | 0.6121 | 0.9101 |
| 12(13)-EpOME | 0.6249 | 1.4026 | 0.6831 | 1.3418 | 0.7220 | 1.2256 |
| 12-HEPE | 1.0586 | 1.5891 | 1.6135 | 1.1480 | 0.1590 | 0.4318 |
| 12-HETE | 1.1469 | 1.2002 | 1.5899 | 0.9906 | 0.3797 | 0.6927 |
| 12-HpETE screen | NA | NA | NA | NA | NA | NA |
| 13-HODE | 0.5619 | 1.3246 | 1.4137 | 1.4274 | 0.3724 | 0.9001 |
| 13-HOTE | 0.4674 | 1.3862 | 1.1133 | 1.4601 | 0.3908 | 1.1822 |
| 13-KODE | 0.6551 | 0.9149 | 0.9627 | 1.1423 | 0.8252 | 1.4998 |
| 14_15-DiHETE | NA | NA | NA | NA | NA | NA |
| 14_15-DiHETrE | 1.1618 | 1.2341 | 1.2948 | 1.0665 | 0.4769 | 0.7659 |
| 14(15)-EpETE | NA | NA | NA | NA | NA | NA |
| 14(15)-EpETrE | 1.3583 | 0.9041 | 1.1881 | 0.6567 | 1.0211 | 0.8718 |
| 14-HDoHE | 0.8723 | 1.2853 | 1.3402 | 1.0737 | 0.5203 | 0.9083 |
| 15_16-DiHODE | 0.8055 | 1.0427 | 0.8707 | 0.8103 | 0.8558 | 1.6150 |
| 15(16)-EpODE | 0.5021 | 1.5500 | 0.6738 | 1.2246 | 0.5508 | 1.4987 |
| 15-deoxy PGJ2 | 2.5068 | 0.4564 | 1.4467 | 0.1668 | 0.6283 | 0.7951 |
| 15-HEPE | 0.9681 | 1.5705 | 1.7495 | 1.0204 | 0.2549 | 0.4366 |
| 15-HETE | 1.2800 | 1.0303 | 1.4592 | 0.9324 | 0.5824 | 0.7157 |
| 15-HpETE screen | NA | NA | NA | NA | NA | NA |
| 15-KETE | 1.0692 | 0.9534 | 1.2814 | 0.7126 | 1.0540 | 0.9294 |
| 15-Keto PGE2 | 2.3157 | 0.3903 | 0.8338 | 0.2777 | 1.0831 | 1.0994 |
| 16(17)-EpDPE | NA | NA | NA | NA | NA | NA |
| 17_18-DiHETE | 0.6904 | 0.9928 | 1.5250 | 0.8105 | 0.6795 | 1.3018 |
| 17(18)-EpETE | NA | NA | NA | NA | NA | NA |
| 17-HDoHE | 0.8223 | 1.1875 | 1.0606 | 0.8500 | 0.9115 | 1.1682 |
| 19_20-DiHDoPA | 1.0964 | 1.5801 | 1.0878 | 1.2179 | 0.4187 | 0.5991 |
| 19(20)-EpDPE | 0.8391 | 1.4430 | 0.8535 | 0.5099 | 1.3345 | 1.0199 |
| 20-HETE | 1.8351 | 1.7402 | 1.3480 | 0.8383 | 0.1592 | 0.0792 |
| 4-HDoHE | 0.9334 | 0.7000 | 0.5662 | 0.3799 | 1.5629 | 1.8577 |
| 5_15-DiHETE | 1.1188 | 0.5090 | 2.9805 | 0.5594 | 0.2407 | 0.5915 |
| 5_6-DiHETrE | 0.9966 | 1.2785 | 1.5403 | 0.9161 | 0.5638 | 0.7047 |
| 5-HEPE | 2.0600 | 0.9086 | 0.8857 | 0.8086 | 0.5800 | 0.7571 |
| 5-HETE | 1.7974 | 0.6254 | 0.9569 | 0.4711 | 0.9902 | 1.1591 |
| 5-HpETE screen | NA | NA | NA | NA | NA | NA |
| 5-KETE | 1.1709 | 0.8263 | 1.0069 | 0.6021 | 1.1740 | 1.2197 |
| 6-keto PGF1a | 2.3641 | 0.5080 | 1.2417 | 0.2962 | 0.6041 | 0.9859 |
| 6-trans-LTB4 | 1.1138 | 1.0408 | 1.5310 | 0.9345 | 0.4347 | 0.9450 |
| 8_15-DiHETE | 0.9724 | 1.2225 | 1.8308 | 1.2507 | 0.1953 | 0.5284 |
| 8_9-DiHETrE | 1.0839 | 1.5982 | 1.3217 | 1.0009 | 0.4645 | 0.5309 |
| 8(9)-EpETrE | 0.8232 | 0.6418 | 1.0476 | 0.5229 | 1.6837 | 1.2808 |
| 8-HETE | 1.6158 | 0.8565 | 1.6251 | 0.7789 | 0.4385 | 0.6852 |
| 9_10-DiHODE | 0.5294 | 1.4118 | 0.8824 | 1.2605 | 0.4538 | 1.4622 |
| 9_10-DiHOME | 0.5855 | 1.3870 | 1.0166 | 1.1553 | 0.6346 | 1.2209 |
| 9_10-e-DiHO | 0.8605 | 0.9771 | 1.8799 | 0.8901 | 0.3780 | 1.0143 |
| 9_10-EpO | 1.0111 | 1.1883 | 1.4721 | 0.8195 | 0.5091 | 0.9998 |
| 9(10)-EpODE | 0.6889 | 1.1073 | 0.8394 | 1.3458 | 0.6929 | 1.3258 |
| 9(10)-EpOME | 0.6532 | 1.3455 | 0.8005 | 1.3002 | 0.7280 | 1.1727 |
| 9_12_13-TriHOME | 0.7685 | 0.8593 | 1.4022 | 0.9643 | 0.7347 | 1.2711 |
| 9-HEPE | 1.6081 | 1.2849 | 1.7104 | 0.8733 | 0.1170 | 0.4063 |
| 9-HETE | 1.3523 | 1.1167 | 1.6918 | 0.8934 | 0.4001 | 0.5457 |
| 9-HODE | 0.6566 | 1.0744 | 0.9273 | 1.0380 | 0.7377 | 1.5661 |
| 9-HOTE | 0.4433 | 1.5567 | 0.6649 | 1.4691 | 0.8041 | 1.0619 |
| 9-KODE | 0.6872 | 1.0785 | 0.9690 | 0.9115 | 0.8392 | 1.5145 |
| Lipoxin A4 | 1.4324 | 0.9729 | 1.6033 | 0.7622 | 0.4238 | 0.8054 |
| LTB4 | NA | NA | NA | NA | NA | NA |
| LTB5 | NA | NA | NA | NA | NA | NA |
| PGD2 | 1.9368 | 0.6747 | 1.6699 | 0.7330 | 0.3166 | 0.6691 |
| PGE1 | 2.2650 | 0.4801 | 0.9428 | 0.3294 | 0.6757 | 1.3070 |
| PGE2 | 2.4712 | 0.6693 | 1.2518 | 0.3928 | 0.4607 | 0.7542 |
| PGE3 | 2.5606 | 0.8509 | 1.3965 | 0.6159 | 0.2071 | 0.3690 |
| PGF2a | 1.7449 | 0.8070 | 1.5328 | 0.4816 | 0.7037 | 0.7300 |
| Resolvin D1 | NA | NA | NA | NA | NA | NA |
| TXB2 | 2.2894 | 0.3607 | 1.0026 | 0.2833 | 1.1762 | 0.8878 |
Factors:
| F1 | Tissue:Left Lung | Treatment:Control |
| F2 | Tissue:Left Lung | Treatment:Simvastatin |
| F3 | Tissue:Right Lung | Treatment:Control |
| F4 | Tissue:Right Lung | Treatment:Simvastatin |
| F5 | Tissue:Trachea | Treatment:Control |
| F6 | Tissue:Trachea | Treatment:Simvastatin |
