Data for Identification of RXR Ligands (Study ST000890)
(Analysis AN001452)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 |
|---|---|---|---|---|---|---|---|---|
| Fatty Acid C18:3 α-Linoleic acid | 0.6765 | 0.4867 | 2.8567 | NA | 1.3196 | 1.3648 | 0.5755 | 0.4391 |
| Fatty Acid C20:2 Eicosadienoic acid | 0.6988 | 0.4899 | 2.7736 | NA | 1.4332 | 1.4543 | 0.4549 | 0.3241 |
| Fatty Acid C20:3 Mead acid | 0.7716 | 0.5721 | 1.8881 | NA | 1.6460 | 1.4206 | 0.5782 | 0.4642 |
| Fatty Acid C20:5 | 0.7532 | 0.6287 | 1.8448 | NA | 1.7275 | 1.7426 | 0.0654 | 0.0595 |
| Fatty Acid C22:0 Behenic acid | 0.6327 | 0.6831 | 2.6363 | NA | 1.2983 | 1.4760 | 0.3687 | 0.3983 |
| Fatty Acid C22:1 Erucic acid | 0.5671 | 0.6166 | 2.4195 | NA | 1.6586 | 1.2041 | 0.6055 | 0.6119 |
| Fatty Acid C22:2 Docosadienoic acid | 0.2629 | 0.3260 | 2.0639 | NA | 1.7631 | 1.7076 | 0.7694 | 0.7207 |
| Fatty Acid C22:3 | 0.4118 | 0.3263 | 3.0164 | NA | 1.6216 | 1.8011 | 0.3386 | 0.2028 |
| Fatty Acid C22:4 Docosateraenoic acid | 1.2980 | 0.7747 | 1.4577 | NA | 0.5384 | 0.3613 | 1.9395 | 1.1358 |
| Fatty Acid C22:5 | 1.2212 | 0.7835 | 1.0106 | NA | 0.3748 | 0.3972 | 2.1007 | 1.5161 |
| Fatty Acid C22:6 Docosahexaenoic acid | 0.6549 | 0.4234 | 2.4907 | NA | 1.8259 | 1.7699 | 0.1236 | 0.1360 |
| Fatty Acid C24:0 Lignoceric acid | 1.3141 | 1.5920 | 1.2575 | NA | 0.6474 | 0.6030 | 0.6593 | 0.7122 |
| Fatty Acid C24:1 | 0.8740 | 0.8026 | 2.0743 | NA | 1.2872 | 1.4622 | 0.3517 | 0.3142 |
| Fatty Acid C24:2 | 2.1964 | 1.9278 | 0.7289 | NA | 0.3263 | 0.2761 | 0.4680 | 0.2832 |
| Fatty Acid C24:3 | 0.6871 | 0.4908 | 2.0637 | NA | 1.2151 | 2.0586 | 0.3072 | 0.2564 |
| Fatty Acid C24:4 | 1.6023 | 0.7621 | 1.6258 | NA | 0.4615 | 0.3065 | 1.6249 | 1.0543 |
| Fatty Acid C24:5 | 1.3743 | 0.5108 | 2.5229 | NA | 0.9223 | 0.5091 | 1.3338 | 0.6329 |
| Fatty Acid C24:6 | 1.4115 | 0.7481 | 1.4867 | NA | 1.9258 | 1.1401 | 0.1651 | 0.1084 |
| Fatty Acid C26:0 Cerotic acid | 1.3996 | 2.1777 | 0.3952 | NA | 0.2169 | 0.2281 | 0.9730 | 1.0049 |
| Fatty Acid C26:1 | 0.9518 | 1.9303 | 2.3692 | NA | 0.8739 | 0.7451 | 0.0415 | 0.0327 |
| Fatty Acid C26:2 | 2.8053 | 1.4048 | 1.0022 | NA | 0.4543 | 0.3928 | 0.0639 | 0.1011 |
| Fatty Acid C26:3 | 2.0133 | 0.8602 | 1.5215 | NA | 0.8964 | 1.0629 | 0.1290 | 0.0797 |
| Fatty Acid C26:4 | 1.9954 | 0.7390 | 2.1734 | NA | 0.7913 | 0.9571 | 0.1541 | 0.1753 |
Factors:
| F1 | Diet of subject mice:control chow | Feeding period (wk):12 | PHZ dose (mg):1 |
| F2 | Diet of subject mice:control chow | Feeding period (wk):12 | PHZ dose (mg):mock |
| F3 | Diet of subject mice:control chow | Feeding period (wk):4 | PHZ dose (mg):1 |
| F4 | Diet of subject mice:control chow | Feeding period (wk):4 | PHZ dose (mg):mock |
| F5 | Diet of subject mice:Non-fat-diet | Feeding period (wk):4 | PHZ dose (mg):1 |
| F6 | Diet of subject mice:Non-fat-diet | Feeding period (wk):4 | PHZ dose (mg):mock |
| F7 | Diet of subject mice:vitamin A deficient diet | Feeding period (wk):12 | PHZ dose (mg):1 |
| F8 | Diet of subject mice:vitamin A deficient diet | Feeding period (wk):12 | PHZ dose (mg):mock |
