Data for (Study ST001439)

(Analysis AN002403)

Values for each metabolite have been scaled by dividing by the mean across all factors

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MetaboliteF1F2
1H-Imidazole-4-propionic acid 1.2380 0.4050
1-Methyl-4-imidazoleacetic acid 0.6759 1.1297
1-Methylhistidine and/or 3-Methylhistidine 1.0588 0.9412
2,6-Diaminopimelic acid 0.8627 1.1373
2-(Creatinine-3-yl)propionic acid 0.8400 1.2133
2^-Deoxycytidine 0.6257 1.3743
2^-Deoxyguanosine 0.6939 1.3061
2-Hydroxy-4-methylvaleric acid 1.0690 0.9310
2-Hydroxyglutaric acid 1.0000 NA
2-Hydroxyvaleric acid 0.8571 1.2857
3^-CMP and/or 2^-CMP 1.0000 1.0000
3-Hydroxybutyric acid 1.1512 0.8791
3-Indoxylsulfuric acid 0.4674 1.5326
3-Methylguanine 0.9756 1.0244
3-Ureidopropionic acid NA 1.0000
4-Acetamidobutanoic acid NA 1.0000
4-Methyl-2-oxovaleric acid and/or 3-Methyl-2-oxovaleric acid 1.0615 0.9231
4-Pyridoxic acid 0.8837 1.1163
4-(β-Acetylaminoethyl)imidazole 0.7500 1.1667
5,6,7,8-Tetrahydrobiopterin 0.6667 1.5000
5-Aminovaleric acid 1.2375 0.5250
5-Hydroxylysine 1.2381 0.7619
5-Methylcytosine 0.9000 1.2000
5-Oxoproline 1.0143 0.9857
7,8-Dihydrobiopterin 0.8167 1.2444
7-Methylguanine 0.9855 1.0145
8-Hydroxyoctanoic acid and/or 2-Hydroxyoctanoic acid NA NA
Adenine 1.3972 0.3380
Adenosine 1.2500 0.6667
ADMA 0.9600 1.0667
ADP 1.0000 NA
ADP-ribose 1.0938 0.6250
Ala 1.0256 0.9744
Allantoic acid 0.2128 1.7872
Allantoin 1.0087 0.9913
AMP 1.1915 0.8085
Arg 1.0826 0.9174
Arg-Glu 1.7973 0.6811
Argininosuccinic acid 0.9714 1.0286
Ascorbate 2-sulfate 0.5333 1.7778
Asn 1.0263 0.9737
Asp 1.0633 0.9367
Azelaic acid 0.9231 1.0769
Betaine 0.9610 1.0390
Betaine aldehyde_+H2O 0.2857 1.2381
Biopterin NA 1.0000
Cadaverine 1.3714 0.5357
Carboxymethyllysine 0.9649 1.0351
Carnitine 1.0545 0.9455
cGMP NA 1.0000
Choline 1.0085 0.9915
Citric acid 1.2059 0.7941
Citrulline 1.0821 0.9179
CMP 1.1045 0.8955
CMP-N-acetylneuraminate 1.0000 1.0000
Creatine 0.9625 1.0375
Creatinine 0.7911 1.2611
Cys 1.0395 0.9605
Cys-Gly 0.9811 1.0189
Cysteic acid 1.0000 1.0000
Cysteine glutathione disulfide 1.0187 0.9888
Cysteinesulfinic acid 1.6000 0.8000
Cystine 0.6667 1.3333
Cytidine 1.0827 0.9173
Cytosine 0.9419 1.0581
Daminozide, Ala-Ala 0.9595 1.0405
dAMP 1.1259 0.9244
dCMP 0.9529 1.0376
Desthiobiotin 1.0000 NA
Diethanolamine 1.0193 0.9759
Diethylaminomalonic acid 1.0435 0.9565
Digalacturonic acid 0.7500 1.2500
Diphenylcarbazide NA 1.0000
dTMP 0.8760 1.1240
Dyphylline 0.9488 1.0640
Ethanolamine 0.9835 1.0165
Ethanolamine phosphate 1.2143 0.8571
Ethyl glucuronide 1.0667 0.9167
Formiminoglutamic acid 1.2375 0.7031
Fructose 6-phosphate 1.1250 0.7500
Fumaric acid 0.9872 1.0051
GABA 1.1307 0.8258
Galactosamine and/or Glucosamine 0.8437 1.3125
Galacturonic acid-3 1.1429 0.8571
Gln 1.0144 0.9856
Glu 1.0901 0.9099
Glucaric acid 1.2471 0.7529
Gluconic acid 1.3259 0.6741
Gluconolactone 1.2276 0.7724
Glucose 1-phosphate 1.0000 1.0000
Glucose 6-phosphate 1.2632 0.7368
Glucuronic acid-1 and/or Galacturonic acid-1 0.6475 1.3525
Glucuronic acid-2 and/or Galacturonic acid-2 0.9381 1.0619
Glu-Glu 0.8231 1.1769
Glutathione (GSH) 0.7692 1.2308
Glutathione (GSSG)_divalent 0.6821 1.2385
Gly 1.0064 0.9936
Gly-Asp 0.8889 1.1111
Glyceric acid 1.1459 0.8541
Glycerol 1.0354 0.9646
Glycerol 3-phosphate 1.1915 0.8085
Glycerophosphocholine 1.0421 0.9579
Gly-Gly 1.1102 0.8898
Glyoxylic acid NA 1.0000
GMP 0.8000 1.3333
Guanine 1.5362 0.4638
Guanosine 0.9591 1.0409
Hexanoic acid 1.0000 NA
His 1.0518 0.9482
His-Glu 0.9157 1.0843
Homovanillic acid 1.1818 0.8182
Hydroxyproline 1.0417 0.9583
Hypotaurine 1.1171 0.8829
Hypoxanthine 1.2379 0.7621
Ile 1.0164 0.9836
IMP 1.0000 NA
Inosine 1.0784 0.9216
Isethionic acid 0.6460 1.3540
Isobutyric acid and/or Butyric acid 1.4586 0.5414
Isocitric acid 1.0000 NA
Isoglutamic acid 0.6863 1.4706
Isovaleric acid and/or Valeric acid 1.0185 0.9722
Isovalerylalanine and/or N-Acetylleucine 1.1429 0.8571
Lactic acid 0.6126 1.3874
Lauric acid 1.0000 1.0000
Leu 1.0093 0.9907
Lys 1.0334 0.9666
Malic acid 1.0296 0.9704
Mannosamine 1.0345 0.9310
Met 1.0337 0.9663
Methionine sulfoxide 1.0058 0.9942
Mevalonic acid 1.0667 0.6667
Mucic acid 1.1163 0.8837
myo-Inositol 1-phosphate and/or myo-Inositol 3-phosphate 1.2500 0.8333
myo-Inositol 2-phosphate 1.0588 0.9412
N1-Acetylspermine 1.0000 1.0000
N1,N8-Diacetylspermidine 1.3370 0.7304
N2-Succinylornithine 1.2143 0.5714
N6-Methyladenine 0.9508 1.0492
N6,N6,N6-Trimethyllysine 0.9630 1.0370
N8-Acetylspermidine 0.8073 1.1927
N-Acetylalanine 0.9024 1.0976
N-Acetylasparagine 1.0435 0.9565
N-Acetylaspartic acid 1.4857 0.5143
N-Acetylcysteine 1.0000 1.0000
N-Acetylgalactosamine, N-Acetylmannosamine and/or N-Acetylglucosamine 1.0455 0.9545
N-Acetylglucosamine 1-phosphate 1.2500 0.7500
N-Acetylglutamic acid 1.4795 0.5205
N-Acetylglutamine 0.9000 1.1000
N-Acetylglycine 1.1032 0.8710
N-Acetylhistidine 1.1321 0.8679
N-Acetyllysine 0.8277 1.1723
N-Acetylmethionine 0.8657 1.1343
N-Acetylmuramic acid 1.1765 0.8235
N-Acetylneuraminic acid 0.3056 1.6944
N-Acetylornithine 0.7634 1.2366
N-Acetylphenylalanine 1.0000 1.0000
N-Acetylputrescine 0.5663 1.4337
N-Acetylserine 1.2249 0.7751
NAD+ 1.1667 0.5000
N-Carbamoylaspartic acid 1.0000 NA
N-Formylmethionine 0.7692 1.2308
N-Glycolylneuraminic acid 0.8000 1.2000
Nicotinamide 1.3258 0.6742
Nicotinic acid 1.1429 0.8571
NMN 1.5455 0.4545
O-Acetylcarnitine 1.1129 0.9323
o-Coumaric acid and/or p-Coumaric acid 1.0000 1.0000
Ophthalmic acid 0.9559 1.0441
Ornithine 1.0042 0.9958
O-Succinylhomoserine 1.0000 1.0000
Oxamic acid NA 1.0000
Pantothenic acid 0.7667 1.2333
Pelargonic acid NA 1.0000
Phe 0.9939 1.0061
Phosphorylcholine 0.9315 1.0685
p-Hydroxyphenylacetic acid 1.0000 1.0000
Pro 1.0235 0.9765
Propionic acid 1.1429 0.8571
Putrescine 0.8227 1.2216
Pyridoxamine 0.8065 1.2903
Pyridoxine 1.2000 0.8000
Pyruvic acid 1.0000 NA
Quinic acid 1.3171 0.7463
Quinolinic acid 1.0588 0.9265
Ribose 5-phosphate 1.1077 0.8654
Ribulose 5-phosphate 1.1250 0.7500
S-Adenosylmethionine 0.8205 1.1795
Sarcosine 1.1351 0.8649
Sedoheptulose 7-phosphate 1.0000 NA
Ser 0.9539 1.0461
Ser-Glu 0.9547 1.0453
S-Lactoylglutathione 1.0000 1.0000
S-Methylmethionine 1.2500 0.9167
Spermidine 1.1023 0.8977
Spermine 0.8000 1.3333
S-Sulfocysteine 1.1444 0.8556
Stachydrine 0.8395 1.1605
Suberic acid 1.1250 0.7500
Succinic acid 1.2184 0.7816
Taurine 0.8745 1.1255
Terephthalic acid 1.0204 0.9796
Thiamine 0.6667 1.3333
Thiamine phosphate 1.1667 0.7778
Thiaproline 0.2437 2.0084
Thr 1.0354 0.9646
Thr-Asp 0.7269 1.2185
Threonic acid 1.0800 0.9200
Thymidine 0.9076 1.0924
Triethanolamine 1.0000 NA
Trimethylamine 1.2222 0.8889
Trimethylamine N-oxide 0.3947 1.4035
Trp 1.0351 0.9649
Tyr 1.0262 0.9738
Tyramine NA 1.0000
Tyr-Glu 0.9508 1.0492
Tyrosine methyl ester 0.4444 1.5556
UDP-glucose and/or UDP-galactose 1.1111 0.6667
UDP-N-acetylgalactosamine and/or UDP-N-acetylglucosamine 1.1636 0.7273
UMP 1.1707 0.8293
Uracil 1.2364 0.7636
Urea 0.5416 1.3667
Ureidoglycolic acid NA 1.0000
Uric acid 0.9823 1.0177
Uridine 1.1216 0.8784
Urocanic acid 0.5548 1.4452
Val 1.0391 0.9609
Xanthine 1.1213 0.8787
Xanthosine 1.0000 1.0000
Xanthurenic acid NA 1.0000
β-Ala 1.0240 0.9600
β-Ala-Lys 1.4211 0.7895
γ-Butyrobetaine 0.8727 1.1273
γ-Glu-Cys 1.1136 0.8864
γ-Glu-Val-Gly 1.0660 0.9175
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Factors:

F1Genotype:DAOG181R
F2Genotype:wild type
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