Metabolite_name RefMet_name S00015200 S00015209 S00015215 S00015218 S00015224 S00015233 S00015236 S00015239 S00015202 S00015211 S00015217 S00015220 S00015226 S00015235 S00015238 S00015241 S00015201 S00015210 S00015216 S00015219 S00015225 S00015234 S00015237 S00015240 S00015194 S00015197 S00015203 S00015206 S00015212 S00015221 S00015227 S00015230 S00015242 S00015196 S00015199 S00015205 S00015208 S00015214 S00015223 S00015229 S00015232 S00015244 S00015195 S00015198 S00015204 S00015207 S00015213 S00015222 S00015228 S00015231 S00015243 Factors - Genotype:FLOX | Intestinal Segment:Duodenum Genotype:FLOX | Intestinal Segment:Duodenum Genotype:FLOX | Intestinal Segment:Duodenum Genotype:FLOX | Intestinal Segment:Duodenum Genotype:FLOX | Intestinal Segment:Duodenum Genotype:FLOX | Intestinal Segment:Duodenum Genotype:FLOX | Intestinal Segment:Duodenum Genotype:FLOX | Intestinal Segment:Duodenum Genotype:FLOX | Intestinal Segment:Illeum Genotype:FLOX | Intestinal Segment:Illeum Genotype:FLOX | Intestinal Segment:Illeum Genotype:FLOX | Intestinal Segment:Illeum Genotype:FLOX | Intestinal Segment:Illeum Genotype:FLOX | Intestinal Segment:Illeum Genotype:FLOX | Intestinal Segment:Illeum Genotype:FLOX | Intestinal Segment:Illeum Genotype:FLOX | Intestinal Segment:Jejunum Genotype:FLOX | Intestinal Segment:Jejunum Genotype:FLOX | Intestinal Segment:Jejunum Genotype:FLOX | Intestinal Segment:Jejunum Genotype:FLOX | Intestinal Segment:Jejunum Genotype:FLOX | Intestinal Segment:Jejunum Genotype:FLOX | Intestinal Segment:Jejunum Genotype:FLOX | Intestinal Segment:Jejunum Genotype:Knockout | Intestinal Segment:Duodenum Genotype:Knockout | Intestinal Segment:Duodenum Genotype:Knockout | Intestinal Segment:Duodenum Genotype:Knockout | Intestinal Segment:Duodenum Genotype:Knockout | Intestinal Segment:Duodenum Genotype:Knockout | Intestinal Segment:Duodenum Genotype:Knockout | Intestinal Segment:Duodenum Genotype:Knockout | Intestinal Segment:Duodenum Genotype:Knockout | Intestinal Segment:Duodenum Genotype:Knockout | Intestinal Segment:Illeum Genotype:Knockout | Intestinal Segment:Illeum Genotype:Knockout | Intestinal Segment:Illeum Genotype:Knockout | Intestinal Segment:Illeum Genotype:Knockout | Intestinal Segment:Illeum Genotype:Knockout | Intestinal Segment:Illeum Genotype:Knockout | Intestinal Segment:Illeum Genotype:Knockout | Intestinal Segment:Illeum Genotype:Knockout | Intestinal Segment:Illeum Genotype:Knockout | Intestinal Segment:Jejunum Genotype:Knockout | Intestinal Segment:Jejunum Genotype:Knockout | Intestinal Segment:Jejunum Genotype:Knockout | Intestinal Segment:Jejunum Genotype:Knockout | Intestinal Segment:Jejunum Genotype:Knockout | Intestinal Segment:Jejunum Genotype:Knockout | Intestinal Segment:Jejunum Genotype:Knockout | Intestinal Segment:Jejunum Genotype:Knockout | Intestinal Segment:Jejunum 3a_7a_12a-trihydroxycholestanoic acid Coprocholic acid 2.3174 0.0612 0.0388 0.1978 10.7481 0.6203 0.5899 3.0297 0.0155 1.6035 0.0020 1.7829 2.2582 0.5866 0.0135 0.0543 3.0531 5.0684 2.3766 0.5901 3.5781 0.4765 2.0536 1.9197 1.6230 0.9199 3.2875 0.3094 0.6564 0.0604 0.8848 5.2267 1.2804 0.1065 0.0387 5.3738 14.5239 0.1555 0.0831 3.4931 2.5940 0.0223 ?a-Muricholic acid alpha-Muricholic acid 2.0664 0.0977 0.0196 6.3867 4.8118 1.2941 2.9597 3.2506 0.0496 9.8206 0.0050 14.6753 8.3781 7.4685 0.0598 0.5674 5.6850 4.3341 6.1324 6.1104 9.2041 12.8177 2.5753 3.3323 0.7993 0.9370 0.9202 0.0190 1.8346 2.1621 0.1585 0.2564 2.9553 1.3296 9.3004 5.2502 1.7497 2.8096 0.8327 3.1205 0.3748 14.0893 0.0119 10.8567 0.0289 9.1706 3.7346 7.0077 3.4671 9.3158 2.4120 b-Muricholic acid beta-Muricholic acid 18.8766 0.4961 0.2199 91.5925 119.1985 20.0930 37.3278 50.7077 0.3470 149.5015 0.0919 432.0082 85.9873 81.4420 0.2753 5.3864 63.7110 34.1057 267.6919 109.2263 168.9052 277.7720 11.7740 68.2866 10.1676 12.9621 15.4474 1.2314 26.8102 64.8596 4.2455 9.7774 30.4050 12.5267 194.5796 49.2603 17.4459 31.1769 9.5093 18.2219 4.4573 664.4989 0.3814 242.2974 0.4681 105.7443 50.7113 128.3958 29.5237 155.0101 16.3569 Chenodeoxycholic acid Chenodeoxycholic acid 0.6284 0.1674 9.3933 11.0033 4.2342 1.6701 5.0570 10.1714 16.7297 1.7570 5.3067 0.4513 1.3981 13.0511 11.1558 7.7967 9.1741 12.5925 4.4666 0.1783 2.8555 0.3586 0.5727 2.2414 4.1751 0.1028 5.3436 0.2957 0.0183 18.2435 15.1185 0.8601 0.2524 2.1912 0.2418 1.7476 1.4880 Cholic acid Cholic acid 26.3831 4.4717 0.9858 103.4476 107.4458 27.7588 41.2221 54.8004 0.1866 212.8737 523.1755 81.0905 106.0941 1.4346 8.9694 68.6333 113.1704 275.8770 124.4639 168.8645 346.2511 13.7646 82.4185 9.6620 29.3742 17.8550 4.4726 23.5602 53.2955 5.3851 9.2594 42.9672 13.2422 268.0682 39.7019 9.8358 26.3986 7.4414 12.2384 3.2120 797.1083 0.2722 407.7830 0.9542 65.1743 45.1083 103.9832 21.6189 126.2462 24.9799 Deoxycholic acid Deoxycholic acid 0.6282 0.1671 9.3935 11.0036 4.2341 1.6699 5.0569 10.1716 16.7302 1.7568 5.3067 0.4510 1.3978 13.0514 11.1560 7.7968 9.1743 12.5928 4.4665 0.1780 2.8554 0.3583 0.5724 2.2412 4.1750 0.1025 5.3435 0.2954 0.0179 18.2441 15.1189 0.8598 0.2521 2.1910 0.2415 1.7473 1.4878 Glychocholic acid Glycocholic acid 0.1539 0.0117 0.0035 0.5605 1.0590 0.0564 0.0292 0.6992 0.0004 0.3173 3.3818 0.1088 0.2075 0.0019 0.0226 0.2690 0.6149 0.4431 0.9858 0.4288 0.1025 0.0019 0.9402 0.2071 0.2597 0.1398 0.0084 0.0371 0.2051 0.0140 0.0499 0.0724 0.0433 0.9311 0.1496 0.0097 0.0338 0.0090 0.0096 0.0028 1.4683 0.0006 2.6963 0.0078 0.0167 0.0474 0.2123 0.0400 0.1910 0.0284 Glycochenodeoxycholic acid Glycochenodeoxycholic acid 0.0063 0.0046 0.0053 0.0062 0.0161 0.0050 0.0048 0.0135 0.0051 0.0080 0.0054 0.0184 0.0040 0.0055 0.0041 0.0051 0.0071 0.0167 0.0041 0.0108 0.0073 0.0049 0.0050 0.0147 0.0062 0.0069 0.0074 0.0050 0.0051 0.0058 0.0048 0.0057 0.0047 0.0039 0.0082 0.0066 0.0037 0.0048 0.0036 0.0042 0.0038 0.0132 0.0045 0.0208 0.0038 0.0047 0.0044 0.0046 0.0049 0.0057 0.0041 Glycodeoxycholic acid Glycodeoxycholic acid 0.0012 0.0001 0.0081 0.0083 0.0003 0.0010 0.0102 0.0002 0.0083 0.0001 0.0807 0.0006 0.0020 0.0001 0.0006 0.0010 0.0313 0.0039 0.0206 0.0008 0.0036 0 0.0144 0.0002 0.0068 0.0003 0.0001 0.0007 0.0001 0.0003 0.0013 0.0001 0.0132 0.0002 0.0001 0.0001 0.0384 0.0814 0.0001 0.0001 0.0002 0.0001 0 0.0011 0.0004 Glycohyocholic acid Glycohyocholic acid 0.0115 0.0009 0.0333 0.0032 0.0079 0.0055 0.0132 0.0092 0.0185 0.0221 0.0082 0.0308 0.0014 0.0107 0.0192 0.0040 0.0019 0.0033 0.0024 0.0154 0.0013 0.0657 0.0849 0.0025 0.0192 0.0507 0.0027 Glycohyodeoxycholic acid Glycohyodeoxycholic acid 0.0015 0.0002 0 0.0039 0.0062 0.0003 0.0006 0.0041 0.0002 0.0050 0.0003 0.0248 0.0011 0.0012 0.0002 0.0006 0.0020 0.0101 0.0020 0.0075 0.0021 0.0012 0.0046 0.0005 0.0018 0.0004 0.0005 0.0007 0.0002 0.0001 0.0006 0 0.0046 0.0004 0.0001 0.0011 0.0001 0.0001 0.0139 0.0141 0 0.0002 0.0005 0 0.0010 0.0002 Glycolithocholic acid Glycolithocholic acid Glycoursodeoxycholic acid Glycoursodeoxycholic acid 0.0018 0.0001 0.0001 0.0026 0.0074 0.0002 0.0007 0.0087 0.0001 0.0040 0.0001 0.0240 0.0003 0.0001 0.0035 0.0076 0.0027 0.0074 0.0008 0.0012 0 0.0105 0.0034 0.0036 0.0023 0.0001 0.0003 0.0039 0.0002 0.0012 0.0003 0.0006 0.0102 0.0005 0.0021 0.0003 0.0002 0.0002 0.0002 0.0109 0.0002 0.0322 0.0001 0.0002 0.0002 0.0034 0.0005 0.0028 0.0002 g-Muricholic acid (hyocholic acid) Hyocholic acid 0.1242 0.0042 0.0012 0.8581 1.8027 0.0891 0.2666 0.4063 0.0017 4.0573 0.0007 4.7134 3.1636 1.0400 0.0010 0.0347 0.8064 0.4851 4.0995 0.7880 3.2490 9.3893 0.0481 0.5344 0.0366 0.0991 0.0468 0.0038 0.1408 0.6078 0.0083 0.0407 0.2660 0.0667 8.1790 0.4876 0.2067 0.3152 0.0812 0.1746 0.0536 22.4618 0.0007 7.4014 0.0010 1.3230 0.3083 3.0209 0.1798 6.2448 0.1140 Hyodeoxycholic acid Hyodeoxycholic acid 0.1010 0.0330 0.0035 1.8227 1.8883 0.6784 0.0963 0.4756 0.0026 6.2540 0.0015 7.2578 1.1402 2.5530 0.0074 0.0921 0.4954 2.8150 2.0332 2.2171 2.6364 6.0703 0.0157 0.4012 0.0235 0.1483 0.0048 0.0084 1.3026 0.2738 0.0097 0.0094 0.8189 0.0291 1.6420 0.0547 0.0827 0.9246 0.0379 0.0326 0.0069 4.3376 0.0029 2.0943 0.0010 0.7643 1.6606 0.7372 0.0746 0.3831 0.3151 Isolithocholic acid Isolithocholic acid 0.2334 0.0217 Lithocholic acid Lithocholic acid 0.1025 0.0519 0.0604 0.0185 0.0188 0.0244 0.0028 0.0982 0.0124 0.1267 0.0418 0.0057 0.0115 0.0986 0.0583 0.0287 0.0612 0.0478 0.0055 0.0256 0.0043 0.0172 0.0037 0.0025 0.0262 0.0047 0.0155 0.5373 0.0127 0.0205 0.0050 0.0172 0.0174 0.1492 0.0065 0.0192 0.0029 0.0122 0.0031 Tauro-alpha-muricholic acid Tauro-alpha-muricholic acid 182.7412 31.2015 7.7139 260.4351 826.7803 114.0855 68.9627 489.4664 0.1849 383.7088 0.3853 687.6796 434.1754 236.0250 1.9973 19.9845 228.5984 528.4691 716.3359 283.7841 555.9308 246.3618 1.7695 431.4165 258.6790 228.9640 150.4010 38.4597 5.5365 336.4938 34.8736 79.3891 76.3473 149.5319 618.2590 223.6921 1.0406 1.1014 3.3138 0.4314 0.1920 696.3098 1.7167 826.5460 11.1741 93.7258 5.4922 466.6174 23.0450 390.1191 14.0871 TAURO-BETA-MURICHOLIC ACID Tauro-beta-muricholic acid 821.9420 65.7850 24.2497 341.3586 1677.3890 178.4781 306.6801 1389.4320 0.5207 642.7341 2.1210 1731.8770 240.1933 173.6226 2.9112 17.6827 1091.4400 1190.8270 1258.6420 685.6458 578.7899 152.3780 3.0232 1301.1430 1337.2960 474.0340 814.1309 242.9250 73.7505 1124.1430 270.5725 358.0648 134.4876 488.8699 1067.1070 601.5273 6.8759 14.7391 10.4764 3.6473 1.2635 1239.9870 10.4603 1941.4970 85.7077 670.6898 105.2372 1056.7250 240.3247 1231.1020 19.3478 Taurochenodeoxycholic acid Taurochenodeoxycholic acid 1.5402 0.3149 0.0095 0.7865 35.3602 0.7663 0.0050 14.6097 0.0016 0.6100 0.0010 7.7964 0.0313 0.0386 0.0020 0.0093 1.0112 27.1971 2.5621 1.0327 0.9556 0.1945 0.0003 26.0911 4.0656 1.1996 2.7878 0.0591 0.0029 1.6570 0.0678 0.0814 0.0360 0.2725 1.6025 0.1857 0.0021 0.0014 0.0018 0.0012 0.0004 9.3953 0.0169 29.9977 0.0555 0.0046 0.0019 0.0395 0.0032 0.0023 Taurocholic acid Taurocholic acid 22.6146 7.4000 1.3052 15.7612 19.8852 4.1991 0.0344 9.2728 0.0204 35.7448 3.8090 11.2835 0.2118 0.6635 8.0666 17.5560 38.8866 4.6643 0.0390 50.2423 31.6951 28.6820 1.9271 0.1911 30.8265 3.5238 5.9771 2.4889 4.1968 14.7057 9.6556 0.0446 0.1306 0.0516 0.0457 0.0163 38.9217 0.2677 2.4847 0.4419 0.1631 9.7785 0.7051 2.6921 0.1103 Taurodeoxycholic acid Taurodeoxycholic acid 0.7115 0.7466 0.1356 1.6409 15.3622 0.7335 0.1233 29.1953 0.1151 0.8239 0.1141 16.2790 0.1321 0.2205 0.1144 0.1258 0.3256 49.9914 3.3268 2.6654 0.2882 0.6413 0.1130 52.3417 0.7986 3.3908 0.6389 0.1204 0.1158 1.1985 0.1260 0.1600 0.1670 0.1610 2.7002 0.1416 0.1157 0.1147 0.1141 0.1142 0.1130 19.9351 0.1186 77.4249 0.1256 0.1166 0.1139 0.1601 0.1154 0.1473 0.1163 TAUROHYODEOXYCHOLIC ACID Taurohyodeoxycholic acid 1.1036 0.2999 0.0176 1.1689 3.0560 0.4558 0.0752 3.7650 0.0013 1.7174 0.0016 5.5981 0.0729 0.1604 0.0032 0.0170 1.6038 5.9806 1.0990 2.3044 0.3609 0.0738 0.0008 3.4736 2.4027 1.6638 1.1708 0.1013 0.0623 1.5371 0.1015 0.2295 0.1404 0.3615 2.6945 0.1553 0.0026 0.0039 0.0030 0.0009 0.0006 1.5997 0.0147 6.4140 0.0409 0.0423 0.0100 0.6793 0.0208 0.5295 0.0078 Taurolithocolic acid Taurolithocholic acid 0.0069 0.0033 0.0002 0.0034 0.0373 0.0008 0.0155 0.0467 0.0035 0.0098 0.0049 0.0361 0.0007 0.0005 0.0004 0.0016 0.0020 0.1070 0.0057 0.0043 0.0046 0.0030 0.0001 0.0588 0.0112 0.0055 0.0016 0.0004 0.0007 0.0050 0.0008 0.0005 0.0004 0.0008 0.0087 0.0008 0.0011 0.0009 0.0012 0.0027 0.0005 0.0291 0.0004 0.1131 0.0005 0.0007 0.0003 0.0006 0.0004 0.0125 0.0019 Ursodeoxycholic acid Ursodeoxycholic acid 0.1218 0.0171 0.0138 2.1328 8.7080 1.6837 1.4638 2.5158 0.0060 3.3474 0.0055 3.0058 0.6509 0.8349 0.0100 0.1734 0.6157 0.4965 3.9195 0.8313 4.9056 3.8692 0.1766 2.0508 0.2874 0.2381 0.4130 0.0330 0.4917 1.3433 0.1347 0.0747 1.4432 0.1092 3.0603 0.5854 0.4222 0.2370 0.1163 0.2514 0.0762 4.8737 0.0047 3.5343 0.0090 4.0809 0.5682 2.8790 0.7821 3.9658 0.3892 w-Muricholic acid omega-Muricholic acid 1.2722 0.0626 0.0449 3.5083 4.9980 0.9468 1.7832 1.9665 0.1006 8.8678 0.0159 12.3458 11.6218 6.1889 0.0661 2.1661 3.5785 2.2289 6.7250 3.2639 9.1859 11.2375 2.0951 1.9494 0.6694 0.6615 0.3530 0.1001 1.1716 2.7637 0.3852 0.4181 4.4049 0.7270 8.9755 3.3198 5.8435 2.7724 2.5139 4.0834 1.5272 13.6561 0.0107 9.4745 0.0149 12.2451 2.5942 7.9159 3.3465 10.4976 4.0436