Metabolite_name RefMet_name LV17-07 LV17-08 LV17-09 LV17-10 LV17-11 LV17-12 LV17-01 LV17-02 LV17-03 LV17-04 LV17-05 LV17-06 Factors - Genotype:Fh1-/- CL1 | Treatment:Cas9 Genotype:Fh1-/- CL1 | Treatment:Cas9 Genotype:Fh1-/- CL1 | Treatment:Cas9 Genotype:Fh1-/- CL1 | Treatment:sg1Hira Genotype:Fh1-/- CL1 | Treatment:sg1Hira Genotype:Fh1-/- CL1 | Treatment:sg1Hira Genotype:Fh1 fl/fl | Treatment:Cas9 Genotype:Fh1 fl/fl | Treatment:Cas9 Genotype:Fh1 fl/fl | Treatment:Cas9 Genotype:Fh1 fl/fl | Treatment:sg1Hira Genotype:Fh1 fl/fl | Treatment:sg1Hira Genotype:Fh1 fl/fl | Treatment:sg1Hira 2/3-phosphoglycerate Phosphoglyceric acid 161278336.8000 136244516.6000 140014053.8000 148835306.7000 139967625.5000 202587025 129245685.3000 157768401.5000 138896047.9000 87308679.9500 120749191.2000 104645190 2-hydroxyglutarate 2-Hydroxyglutaric acid 58379905.2200 52984143.5300 55885234.0100 50740765.1700 50735500.0400 54449278.2900 77070560.2200 80417789.9300 87152487.3000 49899743.8600 51772007.9400 48470887.7100 2-oxoglutarate 2-Oxoglutaric acid 102007024.1000 101310692.4000 101846727.7000 110812147 115036239.7000 113340084.1000 214271666.6000 220047498 245852061.2000 167740952.8000 175127204.9000 159803426.5000 3-phosphoserine Phosphoserine 4362898.5270 3709497.9260 2671935.0050 5721515.1700 5553863.3700 4657994.3850 18776436.6200 20604020.6000 20474949.9600 20559437.7800 20580397.9400 17934058.3700 4-hydroxyphenyllactate 4-Hydroxyphenyllactic acid 23883600.8300 22008556.2800 23316311.2200 18662044.9100 19417994.2300 23323683.5800 20190131.4800 24583323.4500 28321705.8000 17154568.1900 18351200.7700 15914669.4400 4-hydroxyphenylpyruvate 4-Hydroxyphenylpyruvic acid 17188871.2700 14058077.5300 17076403.6900 10691241.9100 11522294.7400 14678323.9000 6264060.7950 7749919.5760 8821316.6860 6732662.5170 7515324.8960 6172828.5500 4-hydroxyproline cis-4-Hydroxyproline 278633326.6000 321031619.3000 396548927.4000 368860499.2000 440877784.3000 366686841.4000 319052264.6000 398320552.4000 467552474.4000 363193157.3000 373987300.9000 349704607.7000 6-phosphogluconate 6-Phosphogluconic acid 8765834.0050 7495956.2550 6934072.5470 11141822.6200 9460830.6620 10770096.6100 12447279.2400 14689560.3400 12988133.4500 8235765.8140 9051694.7350 8086226.3450 acetyl-CoA Acetyl-CoA 6432027.2770 5197869.0060 5324366.3460 8844681.3090 9127606.2840 7925718.8120 9173705.1320 8181651.2150 8886104.2820 6788632.1320 6889868.8640 5138885.8880 aconitate trans-Aconitic acid 19842792.9200 14001181.5900 17077397.9500 21667702.0400 19659018.8300 22961010.9100 44210784.0200 49974586.7000 48995565.4800 40934881.4200 43488021.0600 37156724.8900 adenosine Adenosine 14559636.0500 12584263.1100 19900506.9400 15105037.7200 11703338.6800 22236271.3800 10453922.1400 11097265.9800 10322891.5600 10272323.5900 10570436.6300 9877657.8950 adenylosuccinate Adenylsuccinic acid 7660400.0840 6217532.8230 5109649.3540 17406493.7200 15699603.1600 17233842.4300 85974.6244 41651.2743 59675.0200 128499.5587 30688.4199 68175.0373 ADP ADP 132816718.1000 99315592.8900 78274106.0700 116964050.9000 102101236 97750258.2500 109629479.6000 112399849.2000 115739825.6000 103873765.7000 101421102.7000 92311020.4900 ADP-ribose ADP-ribose 4932958.2730 3579741.8930 2600718.4120 5450692.2260 3725462.1030 3786761.8740 1797823.7260 2086325.5920 1930352.8930 1693321.9230 1635090.5310 1611340.5710 alanine Alanine 786142488.4000 654161930.4000 640583490.7000 799742339.8000 752265247.2000 842580537.1000 839047494.2000 952259079.9000 945216956.1000 806705264.7000 842039653.2000 756283524 AMP AMP 68326389.3500 57536413.8200 38883893.1200 90129778.2500 63625620.2200 51438379.1200 35232523.9300 37476451.0800 36326031.6400 48052789.7800 43871878.1500 36799444.2700 arginine Arginine 2021082467 1857133030 2267239059 2063051464 2193315142 2739093855 1440690430 1837574102 2136230306 1306443907 1452244331 1295436048 argininosuccinate Argininosuccinic acid 450421806.8000 381283388.9000 353993430.6000 396553811.6000 374998847.3000 421007570.4000 5518054.3130 6199624.7480 6200640.9270 4753893.8910 5256246.6380 4825546.5340 asparagine Asparagine 48631863.5400 40191911.6100 36938124.4000 56244282.2900 50956718.4400 53408305.0400 29625261.4700 30758288.2600 32483331.5400 30471187.3100 31678383.4400 27213559.1500 aspartate Aspartic acid 225985429.8000 225206230.6000 245044403.4000 311609395.7000 303195540.9000 378917886.5000 1484425952 1670387415 1624905763 1381273997 1416121403 1271808912 ATP ATP 777146207.9000 606874731.5000 537846727.8000 733443031.8000 682146443.9000 821025320.9000 802872043.6000 907735475.6000 867156792.1000 670582231.8000 642014193 604840499.3000 beta-alanine beta-Alanine 220977290.4000 189391928 180505362.8000 351195402.6000 317264921.6000 351096108.1000 215028161.5000 240658665.8000 233575518.1000 138793832.2000 136792062.5000 124971629.6000 betaine Betaine 2212215099 1851076559 1923205500 3475808952 3143322748 3939768332 4417437248 4636805588 4820271973 2422356692 2516284291 2252089959 carnitine Carnitine 816982207.1000 653876169.4000 669558882.3000 1465790643 1335668274 1625823469 1133532628 1347729240 1402363668 700309969.7000 702670309.2000 613470431.9000 carnitine C14 CAR 14:0 698572.5889 391534.3090 546133.0904 3916773.8910 2682190.5830 3663791.8700 1164404.9780 1545050.8820 1443738.2880 684825.2450 386685.4372 436645.0774 carnitine C14:1 CAR 14:1 4880473.8120 5211560.6170 4481896.8520 9066318.0710 7301187.8640 10062350.4000 4521965.6430 9512584.0390 5284832.8540 3428785.5150 4659069.7720 2950072.5470 carnitine C16 CAR 16:0 1921839.0330 1893315.9890 2140361.1810 6751595.9690 6952937.2140 7767461.8950 2543180.3410 2958590.4010 2569737.4450 1038854.2950 1178730.7040 982737.2263 carnitine C16:1 CAR 16:1 495986.4539 561759.4269 439321.2244 4815609.0470 3584374.6000 5091177.2320 1217770.0230 1500740.7100 1785333.0650 887403.1100 608837.3509 334789.8783 carnitine C2 CAR 2:0 1213734612 1048678948 977374430.5000 2010730605 1780835936 1976704939 628188385 701193904.1000 710102863.9000 478989523.8000 473922879 406226788.8000 carnitine C3 CAR 3:0 20577701.5300 19015153.2100 26196161.9400 30894992.6900 30593763.1100 39338625.4200 289145454.7000 337973696 349646270.3000 125516635.5000 132994638.6000 115809660.4000 carnitine C4 CAR 4:0 178141336.6000 152938888.9000 141646144.7000 329418540.4000 301862583.2000 349442527.7000 545535720.5000 641477735.4000 637389438.2000 370748539 387176901.6000 333436813 carnitine C5 CAR 5:0 14651579.9500 12582572.1700 13228350.9100 19584157.6800 17967820.4200 20660138.9000 51660234.0900 60394030.1800 61322566.2300 21157918.6600 22701267.1400 19853925.3200 carnitine C6 CAR 6:0 6741239.6540 5143431.4120 4841938.1930 11144617.9100 9388410.6140 11844563.0900 4452307.3800 4576092.4410 4733453.1640 3418145.8060 3859034.4410 3629113.8190 carnosine Carnosine 15444356.3900 15327265.4100 25832190.0600 21119525.7800 23611107.2200 30667182.8400 15086138.3500 18811188.1600 27476555.8400 13299732.7500 15365123.2800 12201660.5000 CDP CDP 14167676.8300 10643884.4100 9263308.6930 16239265.3700 14795359.1700 13885399.1100 20609808.2900 21699644.9400 21919269.9900 16237861.6700 15947405.6100 14866273.8900 choline Choline 2339436626 1983942345 1992424641 4632575885 4174547137 3283918944 476169890.3000 626350416.4000 755657419.8000 339754954.6000 341496809.6000 297180530.2000 citicoline CDP-choline 15879849.8700 12344471.8500 10647178.4600 15256252.2500 13445662.5300 13184442.9700 7563502.5930 7786909.0030 8252662.0510 3971110.1800 3484807.6620 3389255.3530 citrate Citric acid 1199335648 918188777.7000 988043258.3000 1366089690 1231260311 1272831977 1686325856 1923560664 1745465625 1738914704 1813287882 1715024107 citrulline Citrulline 38358820.8200 41249817.1400 46803601.3600 42469867.0600 43999939.3600 42972232.6000 25264278.8100 28318458.0400 33277287.5200 34116112.1900 33974274.7900 31438160.5500 CMP CMP 2866983.1490 2629070.0930 2222212.7720 5013648.1950 4102001.1620 4361492.0820 4260489.9230 4773697.1200 5091760.0620 4237120.3570 3925676.4660 2667817.6850 CMP-acetylneuraminate 24007380.9200 19570151.4500 18131349.2200 24890079.2500 21277125.9800 25359269.1100 17991993.5700 19222144.8300 19819033.6200 9853977.7550 9606291.8050 9238377.0780 Coenzyme A Coenzyme A 11510392.2800 9425725.8970 6339669.2150 8402876.7280 8658065.1570 6646695.2010 4074018.9730 5924187.2040 6118540.6600 3048845.4640 3105613.9750 2247168.3470 creatine Creatine 22567357745 19512409987 18457344302 25313058433 23584293881 26306401363 22545363683 24217920779 24125542355 18521417444 19227584494 18307177609 creatinine Creatinine 937568100.3000 864780832.9000 1220256182 1154207715 1255150485 1734025952 864935479 1146610867 1421423281 772141507.6000 820943840.7000 711524461.4000 CTP CTP 49382791.0800 36546544.6900 36195772.5200 58341231.2400 54779988.9200 70068055.0700 80883982.7500 96477812.5900 89288099.8300 56970091.8300 55255331.5700 53287648.5200 cyclic ADP-ribose Cyclic ADP-ribose 36500129.1700 27942584.4900 22848429.4900 37913012.3800 34754844.4000 32957825.2200 27161329.7800 30359733.5300 29745928.5200 20754619.0900 21438226.1000 17807020.4400 cyclic AMP 3',5' cyclic AMP 1694448.8610 1085974.6000 754730.9590 1820109.4120 1562709.3610 1793766.5530 1469673.8610 1537484.4920 1666863.3350 929647.3829 968779.8309 846251.3123 cystathionine Cystathionine 10320327.8100 8354240.8010 7080711.9040 8392724.1980 7721087.0090 7993761.1090 21229036.0300 22693156.3700 23662207.8100 61708597.9100 59095511.9100 48850924.8900 cysteate Cysteic acid 4537052.4990 4433353.9790 5070764.4400 13940522.9300 12466020.2600 15753372.4400 1125960.3110 1555268.9580 1901024.0370 1060761.5000 1222712.5980 1053963.4170 cysteinylglycine Cys-Gly 56086482.5900 46287735.7700 40919464.8600 52396766.8700 48401672.8700 52165494.6100 16881322.5700 17876827.1300 18209965.3800 26336756.9600 26567194.2200 22433252.7200 cytidine Cytidine 6492000.3710 4908511.6350 7374019.6260 9159736.6000 9082366.4480 13215162.2900 9550815.3410 11655938.2400 14052291.8600 7524423.1210 6985229.7790 5623832.8750 cytosine Cytosine 7470020.3430 6115804.8710 8137427.4150 9342344.5700 9306459.9000 12865813.2900 10033364.8000 11965180.5500 14242307.2200 8344907.4160 8132601.8600 7016252.2620 dCTP dCTP 1370061.9290 908831.5821 737634.5919 1408369.2950 1364741.3340 1692515.5380 3814237.8790 4773939.0370 4116737.2760 2800253.3320 2767059.7000 2421556.5730 deoxycarnitine 3-Dehydroxycarnitine 376042279 302873786.7000 283657024.4000 517049332.1000 481925221.3000 590380557.8000 225213499 273111709.1000 273116365 171650453.5000 168166173.3000 146532660.3000 dihydroorotate 4,5-Dihydroorotic acid 42690722.9000 32548526.7400 36989761.4900 35945509.1900 37923313.5900 56267240.4500 21772376.5200 26391476.6400 21647876.7300 14749918.3300 15555088.4900 12538729.2000 dihydroxyacetone phosphate Dihydroxyacetone phosphate 193950433.9000 150329873.3000 123578168.3000 197590513.5000 183945150.2000 189338024.2000 132982334.5000 129850925.6000 120844553.5000 111409886.8000 103538834.5000 94892683.3100 dTMP dTMP 666332.4708 578208.3599 312333.2062 446977.7597 427563.6716 632493.3772 897685.3960 753279.6414 737687.8420 702763.8537 888778.9045 640713.9234 dTTP dTTP 7427871.8500 5458595.3390 5147796.3050 7706918.1850 7279256.6430 8488678.1590 15226243.1000 17452742.7500 17138147.0800 11426506.1200 11219458.8100 10740003.6400 flavin adenine dinucleotide FAD 5933126.2790 4431775.2360 3961304.8920 6967771.5170 5761957.3160 6470671.8250 3247948.4560 3695296.9610 3868230.5540 2647634.3590 2918103.1180 2686998.0010 fructose 6-phosphate Fructose 6-phosphate 53921838.5300 37626256.2800 32928142.3100 59775978.6400 44303158.7300 51491650.7300 35539189.2300 38914372.5500 38796712.7300 22791968.3000 20301500.8900 18070158.1000 fructose bisphosphate Fructose 1,6-bisphosphate 152405780.5000 145570750.9000 132288624.8000 149937347.3000 157105537.6000 219940016.2000 105304166.9000 123491989.6000 94030891.9500 58769446.6000 68851303.9700 64101402.2000 fumarate Fumaric acid 1549956408 1290989425 1120049359 1902281988 1761560580 1838423265 122379354.1000 139778019.9000 134842775.1000 103825650.7000 106450818.8000 88596520.2700 gamma-glutamylcysteine gamma-Glutamylcysteine 163346362.4000 142886048.6000 122615754.1000 265843398.1000 250798568 274782437.8000 7539848.3960 9303782.1280 8832795.2030 10298469.4000 11279798.1500 9705267.2400 gamma-glutamylglutamate gamma-Glutamylglutamic acid 6913716.1940 5957470.8480 5304372.1100 8561335.4520 7914835.0020 8730651.4580 7040461.1600 8092989.3980 8271825.3080 7460934.1750 8647298.8850 7448562.3840 gamma-glutamylproline 74783975.8900 62517042.7800 59070939.3800 87810261.4000 82622750.1400 86851437.9900 53629980.9400 58797531.9000 55342028.3000 64933419.4400 67861811 63036961.1800 GDP GDP 32654169.3000 26125448.7500 21549711.0400 33470864.2800 30677354.1900 34343815.5700 21071943.5600 23479580.6400 20954339.2100 17164187.4600 16126448.5200 15827092.8800 GDP-fucose GDP-L-fucose 8376267.5230 6581938.6450 5871726.3750 9520473.9880 8466604.5820 9606624.1830 4203931.8780 4811818.1180 4611739.1070 3110664.7960 3130347.2920 2781768.9090 GDP-glucose GDP-glucose 4292771.0630 3340935.4550 2621906.9680 4407187.4830 3780778.5830 4130824.4750 2844586.1190 3409993.4650 3379671.1220 1889941.6910 2072046.1540 1677194.6560 gluconate Gluconic acid 1336999558 1066777942 979719467.6000 1110616844 1003353302 1168798983 1452955525 1600332522 1599249066 1205564946 1202801929 1005736145 glucose Glucose 186952853.3000 201938943.5000 356135027.1000 230521832.3000 309197655.3000 384159338.6000 205545905.2000 308533489.4000 434068182.2000 194295663.8000 226246731.8000 195461309.5000 glucose 6-phosphate Glucose 6-phosphate 81389250.5200 62431532.8700 55660411.1400 116555910.7000 87131948.7500 96348169.7200 53885352.5800 58379349.6700 61939552.6500 40673031.1900 36237361.6100 31301770.9600 glucuronate Glucuronic acid 12235999.4900 11671540.1800 11457678.2700 14342401.9100 14057270.4100 15286773.2000 5679862.5580 6545239.7700 7459242.1780 5715437.3530 5831066.4660 5119238.8570 glutamate Glutamic acid 1698942506 1397553950 1266438840 1588972849 1443538640 1682668819 3979826943 4598124096 4544582008 2902685937 3007869621 2714176813 glutamine Glutamine 6812176654 5778432979 5807240993 6848921795 6670483329 7700964510 4997493262 5555385979 5715953368 5434812710 5480873397 5025034881 glutathione reduced Glutathione 7575975882 6181328782 5645498507 7218070812 6610058901 7771364769 2708757423 2998444624 2808149536 3794671821 3848630418 3397348572 glyceraldehyde 3-phosphate Glyceraldehyde 3-phosphate 118684429.6000 97925922.0900 86248454.6200 115506173.4000 108217960.3000 120153265.6000 49146047.8200 55524315.2800 49682668.3200 19606720.4200 20880994.3900 17398225.7100 glycerol 3-phosphate sn-Glycero-3-phosphate 156741373.1000 134525975 114024987.1000 224801884.1000 214123888.5000 229168192.8000 92180793.1900 106975188.5000 105157260 107642559.8000 111577521.7000 95479595.4100 glycerylphosphorylcholine sn-Glycero-3-phosphocholine 21029533263 15822031644 15500985438 20146193656 18188787769 24377187205 20334715642 21651402897 21908723148 8746041797 8903032778 8074288186 Glycerylphosphorylethanolamine sn-Glycero-3-phosphoethanolamine 138431191.5000 111708755.3000 108616817.4000 194557192 171859466.5000 202285960.4000 108514844.7000 115054536.4000 124789565 46240037.3100 46195102.4800 39828057.4100 glycine Glycine 74307194.7800 59856472.8700 61156902.4300 83951398.5500 84886280.7000 94125709.9600 51081275.4300 59957598.6500 59533698.4100 42017995.9300 39595803.5300 33241975.9200 glycylglycine Gly-Gly 13433304.2800 12712895.6100 15639539.1000 19545220.2300 21675031.8700 24283971.5400 12905748.4300 19559660.6600 24109495.0200 10237959.4300 11533109.1900 9590120.8700 GMP GMP 6634585.5580 5543281.4540 4549310.9750 7070668.7780 6208357.1560 7087774.2870 3777159.6470 3671664.3920 3929616.5040 3401120.3690 3366212.4930 2982190.4080 GTP GTP 63145792.4500 48194040.7500 43391612.4400 65759800.0700 61451943.2800 81687850.3900 41256194.9900 47663616.7500 40436616.9900 30625098.7600 28908272.4200 29256246.2100 guanidinoacetate Guanidoacetic acid 7671884.0150 6966086.4310 7677384.4400 10631814.6500 10869900.9000 11767751.1800 8026897.2510 8968037.4430 10561330.6800 4673419.4790 5490905.1370 5282606.2980 guanosine Guanosine 2809111.6270 1608034.9270 1578668.0250 3946603.5060 3139168.2570 5491323.9830 2016317.4720 1956930.0090 2404906.6760 1615084.6920 1116680.3000 668344.8695 histidine Histidine 2607586633 2397954440 2843971244 2429770686 2592855422 3062280101 1814123522 2108959981 2460995146 2406988830 2598164815 2386181859 homoarginine Homoarginine 22173536.6400 18752791.9300 22887682.8200 22620427.7800 24217405.6700 29844994.2300 13274894.1000 18248213.8800 21392309.6200 12129742.3300 14320687.4400 12333665.4400 homocitrulline Homocitrulline 3787072.2310 3587914.1860 4336283.2680 4119639.6270 4578764.0710 5623592.0310 3492059.7930 4684607.8610 5174566.2970 2887175.1570 3689889.8110 2060006.7710 homocysteine Homocysteine 1476494.9000 1386654.8540 1526314.3500 1514645.7040 1306851.8240 1938619.6130 1113085.4060 1504514.6300 1543107.7860 1464693.0430 921510.1287 926518.8335 hypotaurine Hypotaurine 31524719.2700 26154971.8800 26603724.3900 44175735.7100 41909350.9600 45233449.4400 27521953.0900 30574772.5200 33135129.9300 19766853.6400 19112696.2300 17860363.5600 IMP IMP 4260694.8880 3856950.3210 3291335.0130 5650713.0420 4776585.9630 4843346.9420 1470698.7340 1618779.6930 2226709.1490 1915769.1790 1752228.8910 1482258.7850 inosine Inosine 4414791.5580 3106558.6490 3136232.6170 4861737.6700 3965852.3640 5030581.4560 2045859.5040 2698325.2330 2780851.4300 2607628.3130 2188529.8650 1635193.6030 inositol Inositol 470436329.5000 422466830.4000 421081327.5000 899042218.9000 842911262.6000 946701422.1000 432614994.5000 448250227.7000 502376161.3000 444242487.1000 429429874.1000 419754608.4000 isoleucine Isoleucine 5322461172 4791765786 5328646709 5649373366 5675199183 6295991716 4245358501 5241380377 5738791857 3446691037 3794088928 3120369572 ketoleucine Ketoleucine 44202579.9000 49335454.9800 88991638.6300 56727952.2000 68131641.3800 107597399 58546049.3900 88505418.6900 137786842.9000 44988579.0400 51707173.9100 42253057.5200 ketovaline Ketoisovaleric acid 8680827.2180 6956679.3000 10420191.9200 8442839.7090 10399349.4000 13561227.7500 8693459.6010 14275199.9000 18538492.7700 8710668.9690 8489007.9930 7697836.3570 kynurenine Kynurenine 11978906.4000 9014821.7560 10486903.8200 10604975.7400 11639530.5900 15992155.7000 9434442.2400 12066903.3700 13103983.5900 7638247.2320 7872669.8100 7108864.5140 lactate Lactic acid 3938113525 3462351517 4492457739 4245884490 4509202908 5969428720 1569868234 2195964763 2805267232 1080362250 1186711465 975239801.5000 leucine Leucine 7007175363 5901331946 6569184347 6544859391 6608573669 9107222433 4827719069 5771011493 6529443734 3968357848 4303907787 3717485116 lysine Lysine 513412111.6000 463888253.9000 644863647.5000 572566893.5000 641304059 880323970 317684366.8000 462187610.9000 591486560.6000 273089694.9000 312713213.5000 254410262.2000 malate Malic acid 262072096.6000 218363945 194455856.8000 435269083.2000 396283595.6000 365197097.2000 1571602219 1779504752 1715917752 1349230371 1379746493 1172582917 methionine Methionine 4350791635 3662827786 3723390288 3978370575 3811787047 4731682562 2918860563 3426978609 3665211443 3214640439 3358780529 3019150894 methylthioadenosine Methylthioadenosine 464404884.8000 338906458.7000 293098218.8000 388270070.4000 342496431.2000 343569969.7000 403869620.3000 458713199.1000 412305750 455813082.9000 446955204 431262498.9000 N6_N6_N6-trimethyllysine N-6-Trimethyllysine 109913125.3000 87085222.7500 88417716.4700 118625273 111913403.6000 129151508.6000 35492043.8600 43951499.0800 53279314.7400 38341687.6800 40591511.8000 33025769.9700 N-acetylarginine N-Acetylarginine 9704348.8330 8746491.0370 7698791.7330 9989083.6550 9136456.8510 9896349.7360 3958012.7500 4609453.1130 5135426.4290 5119749.3570 5107766.2160 4747796.7870 N-acetylaspartate N-Acetylaspartic acid 7377029.0880 6685547.3040 7735729.3600 7715663.1080 7912549.8010 9038689.8690 86755167.6200 100540849.3000 96990488.7400 10813058 10570117.9200 9100260.7230 N-acetylaspartylglutamate N-Acetyl-Asp-Glu 2178564.9020 1580889.6820 1493498.2600 2208400.4810 2101269.3120 2315942.8230 5759944.8040 5910004.0100 6762535.8220 5098013.3580 5570674.8340 4391751.5090 N-acetylglutamate N-Acetylglutamic acid 7070556.6690 6084456.3520 5558403.3300 6952215.3040 6644023.6750 7512817.3290 33836958.5500 38019870.4200 36911444.9900 24469419.2900 24509986.9200 22432632.0300 N-acetylhexosamine phosphate 9730426.0650 6889351.7030 5851843.2680 15838623.4000 13418066.8800 13607696.7000 8213717.8750 8664448.7150 9221704.2030 7330179.5250 6447024.5750 6318544.6040 N-acetylhistidine N-Acetylhistidine 74594019.4900 91750339.8800 186612064.1000 112971290.6000 159809592.5000 218778284 78507968.5200 133676026.2000 192331470.5000 69147407.6200 89487168.4900 71227861.8700 N-acetylneuranimic acid 36284700.8000 33991998 42567161.1900 34182135.2500 34938873 44000604.2900 20922128.4800 28446757.0700 33371421.1700 19186891.1100 22490669.3900 18667576.8900 N-acetylserine N-Acetylserine 402246389.6000 352169877.9000 331739034 608656650.4000 555717437 617432669.2000 814348983.5000 931172275.1000 925665910.6000 762819972.2000 782344873.1000 682768214.9000 NAD NAD+ 257390637.9000 202271529.6000 168761239 273416055.4000 247808162.7000 226039968.6000 209898531 227837908.1000 229226024.1000 159903032.6000 161870342.8000 138284616 NADH NADH 83672082.0800 97852909.5200 122534579.6000 109803509.6000 115187154.1000 222268191 25132279.8300 42920300.9800 33681107.9600 9254026.8050 12845273.9800 11916135.1400 NADP NADP+ 9597337.8590 8458582.8460 11011827.4800 8398322.3730 8444291.7940 14104890.6500 4079253.3690 4650239.8900 4621754.9590 2790065.9360 3133004.4940 2805449.6120 NADPH NADPH 10044272.7000 6514195.6270 2188545.0610 11062484.8600 8778178.0850 5205034.0960 7766375.5800 8647451.6660 8424144.7620 7118886.2060 6793331.0510 6023405.3870 N-carbamoylaspartate N-Carbamoylaspartic acid 8584477.4320 6917324.9140 5753050.7310 7383137.8670 7132361.7150 7737408.3780 8672290.6460 10370429.4300 10196159.0400 7843540.2370 8578425.0040 7238130.8980 N_N-dimethylarginine Dimethylarginine 84175918.2200 67332614.6800 77450355.0100 79799608.9700 76907298.2300 92560883.2000 41175801.9300 53847893.4700 63991568.1000 41760159.8500 45987800.9200 36757150.1400 ophthalmate Ophthalmic acid 5220100.1080 4617210.8170 4241185.0970 3480892.0370 3420999.6640 3455610.1730 175310961.2000 199022108.7000 191495050.1000 78989208.6100 82525334.4900 69671313.4700 ornithine Ornithine 11573459.8300 9634404.2690 13158042.0900 13636494.1200 14915961.3400 17724534.1800 9898182.4740 11874257.1400 16522548.7300 11438666.3800 12717946.1900 10299359.5600 orotate Orotic acid 54149484.0900 27451791.0200 22028903.4700 83784345.8000 63385164.6000 66153955.1900 25352483.7500 23965754.9900 25737477.2800 26962208.4600 20101564.7500 22297504.3800 orotidine Orotidine 10297045.9900 7920058.7050 5654308.6230 13555763.2500 11319631.8400 9648918.8430 32174864.7800 30603482.7300 31401144.3200 21931421.7400 17303624.9800 15521722.9400 oxidized glutathione Oxidized glutathione 46787631.7000 42358662.1700 59827939.4300 49269591.0700 52627139 65931717.2000 16821859.9900 29789068.7300 34742944.5400 20783411.7400 26276948.7200 24012738.7200 pantothenate Pantothenic acid 1160844609 968387763 950031269.5000 1400518457 1322900989 1524291115 493028401.8000 600256793.9000 646811047.8000 444919912.2000 475541714.5000 413574013.6000 pentose phosphate 42183769.0400 33857167.8100 30479113.7200 52415984.7300 43652983.9300 51017347.2000 38267293.9300 38667452.7900 41479971.0400 28372623.7100 29303951.4100 24888198.4000 phenylalanine Phenylalanine 6504986121 5777790939 6576149623 6657717505 6568087014 7775565278 5063976371 6195134207 6777743249 4057054923 4384158375 3733030937 phosphocholine Choline phosphate 30337277152 25047787585 22998050747 32348035710 30630363454 33322811801 38828909696 42242466738 40223189672 33083353214 33526752011 30464894340 phosphocreatine Phosphocreatine 74312290.2100 57933426.3100 52700950.7300 139854769.6000 122446272.8000 157697471.4000 751198092 866230083.4000 844960177.2000 490771582.7000 504155665.7000 445212277.2000 phosphoenolpyruvate Phosphoenolpyruvic acid 34049725.0800 56435015.3200 64023708.8800 64732873.3900 65718427.0900 100635646.4000 7840487.1310 15400951.0400 16091854.2700 11381555.1500 12301372.7800 11409546.7200 proline Proline 5205358199 4298494711 4104693402 4740535860 4304009101 5449028007 11519700915 12898487958 12745905888 10891490714 11157505299 9870395284 pyridoxine Pyridoxine 48317458.1100 49568734.8600 73962906.4800 59990803.4700 72658036 91366473 51396642.8400 72195380.9000 87334736.1200 40849687.5600 47559785.1600 38394558.1900 pyroglutamate Pyroglutamic acid 4447268793 4173703906 5650658910 5293702866 5746426957 7871930570 3765878338 5101484219 5838734841 3138016525 3517697015 2990497013 pyruvate Pyruvic acid 72223410.9400 59475980.2500 94215095.7900 90717527.4800 97998532.2100 170053897.1000 91578157.9400 137494546.6000 182217816.3000 80896975.0800 85197388.0600 70822403.7000 S-(2-succinyl)cysteine 213029683.7000 179035225.7000 174623185 198602375.8000 192273689 227503067.9000 288320.4411 313856.9656 378343.7831 347807.5325 382955.4819 313078.1820 S-adenosylhomocysteine S-Adenosylhomocysteine 8637051.2850 6364419.8290 6353979.4720 14694513.2700 11044275.5400 13589439.4700 7808175.6260 9164950.3520 9214897.0270 5642865.9120 5800361.4460 4697991.3300 S-adenosylmethionine S-Adenosylmethionine 461762696.6000 439717597.8000 402809356.2000 429601288.3000 415847350.1000 451311827.9000 358318622.7000 386642846.2000 379340373.5000 368306644.2000 396538587 367966133.4000 SAICAR SAICAR 11323729.5100 8959567.5400 7559327.7500 42846551.8000 37416939.7800 43700540.1400 363935.7586 398703.4784 351468.5313 289951.0292 262557.6107 191206.5591 sarcosine Sarcosine 15358284.4200 12266151.0300 13799107.9400 20098959.1500 18180652.9000 20598097.5100 9171026.4970 11315694.6000 11020766.6400 3302213.1710 4447058.6830 1527405.3130 sedoheptulose 7-phosphate Sedoheptulose 7-phosphate 13902925.1300 11085009.5800 9733810.2610 10638129.9700 9138241.5770 10854752.7600 15157251.7600 18153797.0400 16822804.5700 8404169.5410 8669797.1910 7330654.6080 serine Serine 277631021.9000 237809268.6000 232369311.3000 324194874.1000 326057845 350741300.3000 196184080.9000 230510962 234974231 168193336 172681812.9000 143651516.6000 S-Succinylglutathione S-Succinylglutathione 138639696.5000 111063172.8000 102389710.5000 133605460.3000 122740582.6000 137027279.4000 1153326.4040 1277946.8330 1264858.2100 1806258.7400 1725123.8620 1470281.7790 succinate Succinic acid 844754707.2000 705838442.8000 612194412.1000 858980849.3000 806892942.3000 899244046.5000 121840785.9000 141366790.7000 153799292 68351768.7900 69707945.6000 58484421.7300 succinyladenosine Succinyladenosine 7761846.9710 6366910.6450 5779143.0060 8576281.2540 7054202.7880 8026198.6260 16316.0500 39924.0226 82886.4602 34501.0349 85431.0947 64367.0494 taurine Taurine 3565572427 3143766800 3587486712 4591334185 4677225703 5195785465 3433302121 4079405444 4702192976 2850464148 3015461180 2682307677 threonine Threonine 3102496855 2748388968 2803947219 3466134401 3449969438 3778889174 2135516298 2626480729 2895862901 2005551177 2152438691 1835844458 tryptophan Tryptophan 1128538944 897957474.4000 998260833.1000 1077658095 1065981107 1442189995 743774677.5000 951347784.9000 1066843461 561824463.7000 622733122.2000 507064375.9000 tyrosine Tyrosine 4867738305 4185847150 4544091104 4671605198 4729592470 6007460797 3526040760 4357148544 4833630960 3013775169 3017706813 2639079091 UDP UDP 86755459.2500 66019167.2500 56185534.5000 97624555.8000 87518684.3800 86748171.3900 105352939.6000 114863445.6000 111637340.7000 89509467.4000 87081368.4500 79801009.6900 UDP-GlcNac UDP-N-acetylglucosamine 867382344.6000 639446587.6000 581084188.6000 1028219713 861109411.2000 1118655252 561403222.7000 655589179.9000 634967524.6000 488056486.2000 489961756.2000 430307436.3000 UDP-glucose UDP-glucose 338387356 266085191.3000 243090679.7000 408810488.3000 361231040.9000 410143369.5000 340711785 397153253.7000 389802158.2000 292975446.3000 288130377 242761800.9000 UMP UMP 28950768.5800 23092149.2600 20770111.7800 60642248.2000 51347046.5600 51451640.3500 19704397.1700 21617307.1400 20982390 20884445.0700 19334594.1800 16384402.1200 uric acid Uric acid 16719372.3100 18431112.9700 65448543.1600 24778070.4200 34094125.0600 111262318.1000 13490767.2800 21428057.9400 56916100.1900 19062779.7500 21135364.2100 15634927.0900 uridine Uridine 2581233.6400 2747461.2560 3498307.5840 4699282.5320 4503482.6570 5475800.1940 2681486.8870 3330815.0400 4483956.3520 2476906.2420 2225083.1110 1852666.6520 UTP UTP 209102564.2000 153518392.7000 141764858.8000 267550965.8000 250960673 307567084.1000 304645549.6000 361210569.9000 332989545.6000 213587369.8000 201773216.6000 192581653.4000 valine Valine 2836218404 2368459814 2760959089 2747840872 2773338071 3599795433 2084555086 2588792097 2892612347 1658594776 1802383451 1551519642 xanthine Xanthine 64165885 61491132.2600 98463531.4400 72016293.1500 86753258.3200 129750450.4000 58415977.8000 80711685.1600 102099562.3000 47366159.5000 54605636.9800 46958208.3000 xanthosine Xanthosine 1370022.6370 1487779.0080 2170847.5050 1635760.0430 1965213.6670 2737810.7270 1110842.0550 1543973.5230 2051991.4740 957301.0298 1222245.9470 859189.8646