Metabolite_name RefMet_name L-isoleucine 1 L-isoleucine 2 L-isoleucine 3 PBS 1 PBS 2 PBS 3 Factors - Group:L-isoleucine Group:L-isoleucine Group:L-isoleucine Group:PBS Group:PBS Group:PBS 1-Methylnicotinamide 1-Methyl nicotinamide 4249390 2863372 2777217 4635830 3562369 3421097 2_3-Diphosphoglyceric acid 2,3-Diphosphoglyceric acid 3-Hydroxybutyric acid 3-Hydroxybutyric acid 1942468 2452051 2141340 2813537 3500328 2316222 3-Phosphoglyceric acid 3-Phosphoglyceric acid 282093 327558 146408 172429 226270 232587 4_5-Dihydroorotic acid 4,5-Dihydroorotic acid 23746 22340 24727 36447 4-Hydroxyproline cis-4-Hydroxyproline 8803071 9408142 6465230 10564256 8091488 13279929 5^-Methylthioadenosine 5'-Methylthioadenosine 8973991 8043298 7062992 8193215 8593253 12044370 5-Phosphoribosylamine 5-Phosphoribosylamine 10869 6-Phosphogluconic acid 6-Phosphogluconic acid 17751 18977 12085 16899 16416 33106 Acetoacetic acid Acetoacetic acid 1460125 1213765 951267 1329576 1290384 1421756 Acetyl-CoA Acetyl-CoA 67917 Acetylcysteine N-Acetylcysteine 74548 115898 198837 135425 97648 350873 Adenine Adenine 83246392 76494512 77880056 88142400 84732496 81453808 Adenosine Adenosine 671242688 651015104 610686272 701713024 683250048 670434240 Adenosine diphosphate ribose ADP-ribose 20692 12308 33185 17502 16728 34444 Adenosine monophosphate AMP 22167626 24772412 26533096 35229224 43344572 52479668 Adenosine triphosphate ATP 81343 94551 65399 73145 78238 99313 Adenylsuccinic acid Adenylsuccinic acid 175204 219253 212402 398024 428242 469944 ADP ADP 2068797 2646324 2166823 2741345 2835510 3590616 Allantoin Allantoin 1767438 1620240 1622055 1622678 1486903 1591407 Aminoadipic acid Aminoadipic acid 526769 342537 345955 449928 415904 421425 Argininosuccinic acid Argininosuccinic acid 137184 140519 131999 144168 126367 147442 Beta-Alanine beta-Alanine 13271733 14381044 10118144 12678376 11905221 13344714 Betaine Betaine 604121920 429970400 377316928 452135840 422163648 475783424 Butyrylcarnitine CAR 4:0 19926424 15704778 12651025 22153812 23200970 17129492 Carbamoyl phosphate Carbamoylphosphate 2099359 2168751 2019106 2193320 2203592 2346300 Carnosine Carnosine 9270963 9280964 7661969 9905975 8222194 7898454 CDP CDP 60896 56641 43636 67820 47997 55959 Choline Choline 720862 575122 542750 746582 663091 661368 cis-Aconitic acid cis-Aconitic acid 2577777 2727502 2324350 2634226 2257640 3983312 Citric acid Citric acid 32668446 31040678 27308106 34585700 27886548 42398588 Citrulline Citrulline 38162784 39763436 38163084 40800616 36428712 41802860 Creatine Creatine 2139475200 2066985728 2347261184 2157418496 2144221440 2193171456 Creatinine Creatinine 52159168 41663524 37787008 47590344 42504876 48190316 Cyclic AMP 3',5' cyclic AMP 61642 72184 64951 58156 61097 104148 Cytidine Cytidine 13815188 11644981 9740854 11580956 10083112 12068753 Cytidine monophosphate CMP 1420778 1662060 1495719 1903435 2037192 2254936 Cytidine triphosphate CTP Cytosine Cytosine D-2-Hydroxyglutaric acid D-2-Hydroxyglutaric acid 10156437 10127568 10459637 10581814 11723587 14084360 D-Glucose Glucose 406158 307895 243837 334106 266379 157164 D-Glyceraldehyde 3-phosphate Glyceraldehyde 3-phosphate 635898 537435 284969 592030 501833 326762 Dihydrofolic acid Dihydrofolic acid Dihydroxyacetone phosphate Dihydroxyacetone phosphate 714110 551120 278415 589966 488559 335261 D-Ribose 5-phosphate Ribose 5-phosphate 821397 1014485 901018 778795 1022638 835045 D-Sedoheptulose 7-phosphate D-Sedoheptulose 7-phosphate 1093804 1061017 967674 1320233 1584729 2144290 dTDP dTDP 13788 FAD FAD 33180 35114 31358 35940 35126 45221 Folic acid Folic acid Fructose 1_6-bisphosphate Fructose 1,6-bisphosphate 48699 34138 33090 44521 34541 70577 Fructose 6-phosphate Fructose 6-phosphate 3834442 700530 1375895 1242128 1579466 3843600 Fumaric acid Fumaric acid 7780646 7419650 6524558 7062854 7081206 6358326 Glucose 6-phosphate Glucose 6-phosphate 1633371 1603117 1774589 1899608 2155604 3951443 Glutathione Glutathione 18172562 22073482 16528939 13958232 13316762 Glycerol 3-phosphate sn-Glycero-3-phosphate 14595171 11274823 10616502 13175567 10405906 10874453 Glycine Glycine 14482960 14835672 13146725 13446512 13766066 14125195 Guanidoacetic acid Guanidoacetic acid 38691744 50616728 31566580 44266984 23038106 37663376 Guanine Guanine 116892304 105537248 97032512 95830144 84810168 96635304 Guanosine Guanosine 25754032 23954416 19821026 21928268 21668552 18762114 Guanosine diphosphate GDP 328575 369201 252377 336102 304869 337912 Guanosine monophosphate GMP 8462942 9357850 10413250 12436119 14257473 15013494 Guanosine triphosphate GTP 14126 12888 14471 Homocysteine Homocysteine 15153 15098 13704 15919 12583 16663 Hypotaurine Hypotaurine 56292332 67908848 57580504 60985584 41285836 81991840 Hypoxanthine Hypoxanthine 370240544 337836000 294658144 315647808 276949536 303414080 Inosine Inosine 32524910 34586652 25885574 27504282 26595778 28834710 Inosinic acid IMP 361805 690707 592513 537142 632003 1601149 L-Acetylcarnitine CAR 2:0 378421344 344848192 273062624 350004160 421838592 332630624 L-Alanine Alanine 28017554 27517926 27770236 26928612 27168492 26577286 L-Arginine Arginine 20584814 14981508 15957908 19267802 16490404 16037659 L-Asparagine Asparagine 3808000 3946038 3255908 3574364 4074160 3968505 L-Aspartic acid Aspartic acid 56184080 52250672 47420456 51364520 54353256 56433260 L-Carnitine Carnitine 811192896 684923968 585865472 736363008 679726976 756743232 L-Cystathionine Cystathionine 2642399 2350286 2088639 2441014 2330690 2530474 L-Cysteine Cysteine L-Cystine Cystine 49977 L-Glutamic acid Glutamic acid 66898100 70089800 68031760 73400824 70128008 81068560 L-Glutamine Glutamine 385018592 395980000 365262976 393044704 396838208 379921280 L-Histidine Histidine 49101808 61957700 50802004 54920856 51775900 54777488 L-Isoleucine Isoleucine 28581514 25268470 21279226 26684316 31188894 26967100 L-Kynurenine Kynurenine 263747 158413 170717 233315 210201 177412 L-Lactic acid Lactic acid 269218624 269157600 209358032 268875168 242419216 262065760 L-Leucine Leucine 22274654 23812256 22030314 26841148 28208258 22457300 L-Lysine Lysine 27671210 18663348 20940600 27695128 24462844 24473440 L-Malic acid Malic acid 83756904 81134728 71607232 77798400 79644560 73069792 L-Methionine Methionine 94893912 75555376 71489640 86296272 76928088 84796032 L-Phenylalanine Phenylalanine 161306400 126483168 151517280 170115440 148272416 175530400 L-Proline Proline 409929984 393898688 368377984 379826336 415305088 421982080 L-Serine Serine 18229188 18815044 15711841 19367272 15587901 18408308 L-Threonine Threonine 3719369 3659611 2650220 3288722 3031066 3757657 L-Tryptophan Tryptophan 80530448 65921188 61259336 85367928 61234424 71711680 L-Tyrosine Tyrosine 198778336 158700144 152740800 177376048 160500496 169280752 L-Valine Valine 41066172 39090104 32330998 41152724 38683484 37911940 N6-Acetyl-L-lysine N6-Acetyllysine N-Acetylglutamic acid N-Acetylglutamic acid 257369 398983 245573 281585 319748 287669 N-Acetylglutamine N-Acetylglutamine 1112962 784954 955111 1158574 1220494 1163992 N-Acetyl-L-alanine N-Acetylalanine 1132596 995509 783137 1021278 794609 930358 N-Acetyl-L-methionine N-Acetylmethionine 294783 289541 181349 213617 227100 176247 N-Acetyl-L-phenylalanine N-Acetylphenylalanine 377111 279092 368527 438353 288825 263076 N-Acetylornithine N-Acetylornithine 294753 178699 158734 220498 266276 209717 N-Acetylserine N-Acetylserine 4570092 4176326 3092084 4484424 3736331 4821056 NAD NAD 742623 759100 840526 1061483 1148056 817346 NADH NADH 26996 31014 27095 37120 40206 27581 NADP NADP 97246 95534 77376 111672 84198 102144 NADPH NADPH Niacinamide Niacinamide 420984608 407195584 399931520 387290240 394347840 439666080 Nicotinic acid Nicotinic acid 28839 26502 30977 O-Phosphoethanolamine Phosphoethanolamine 15151705 13969881 13022355 15939495 15435910 16343020 Ornithine Ornithine 3302452 3256602 2726025 3727926 2999114 3367523 Orotic acid Orotic acid 82255 104052 62050 124166 79501 229893 Orotidylic acid Orotidylic acid 32358 Oxidized glutathione Oxidized glutathione 10031442 7770010 7997618 11046459 9813726 16811650 Oxoadipic acid Oxoadipic acid Oxoglutaric acid 2-Oxoglutaric acid 136539 155272 122377 155222 174454 525512 Palmitic acid Palmitic acid 9233180 12253842 19292610 24043662 79991192 65985864 Pantothenic acid Pantothenic acid 28664986 25615306 21824172 26532986 26991144 29669090 Phenol Phenol Phosphocreatine Phosphocreatine 513842 222393 202683 382459 245577 250369 Phosphoenolpyruvic acid Phosphoenolpyruvic acid 879442 773103 524715 595539 620190 1106507 Phosphoribosyl pyrophosphate Phosphoribosyl pyrophosphate Phosphorylcholine Choline phosphate 854369920 693303808 584894208 765639040 695561920 819299584 Phosphoserine Phosphoserine 10878 12892 Pipecolic acid Pipecolic acid 14439983 12418024 12369291 13908488 15427647 13522105 Propionylcarnitine CAR 3:0 16719592 11420047 9066338 12511647 13065424 13619304 Pyruvic acid Pyruvic acid 569365 536204 476600 604959 609902 606438 Ribose 1-phosphate Ribose 1-phosphate 1979096 2200607 2065145 2247784 2554705 2338502 Saccharopine Saccharopine 66466 40197 54273 53502 78313 52352 S-Adenosylhomocysteine S-Adenosylhomocysteine 913279 835017 729116 1022091 970745 1185353 S-Adenosylmethionine S-Adenosylmethionine 3230051 2976122 3309104 2811616 3658221 3281404 Sarcosine Sarcosine 2364109 3034935 2780678 2561350 2395074 2683546 Succinic acid Succinic acid 8813557 9346692 10005264 11812261 14063670 11648768 Taurine Taurine 472701664 444544832 439155616 459129824 500327808 480981184 Thymidine Thymidine 545556 351938 354332 509427 496505 442047 Uracil Uracil 7026970 7109172 5222488 6203316 5475362 6149857 Ureidopropionic acid Ureidopropionic acid 2841595 2494395 2215581 2530961 2553499 2556492 Ureidosuccinic acid N-Carbamoylaspartic acid 16491 17918 22725 13612 17279 Uric acid Uric acid Uridine Uridine 11296742 11204658 8703716 10407844 8945147 9985778 Uridine 5^-diphosphate UDP 1508570 1368388 1028489 1456240 1242796 1893581 Uridine 5^-monophosphate UMP 7177066 9345739 9861106 11710335 12951104 13934011 Uridine diphosphate glucose UDP-glucose 12686967 10884087 8248676 11232975 9208108 9100103 Uridine diphosphate-N-acetylglucosamine UDP-N-acetylglucosamine 989443 981749 793194 910389 1015516 1127594 Uridine triphosphate UTP 16897 16319 11852 16007 11640 13509 Valerylcarnitine CAR 5:0 5589399 4148155 3727842 5713435 7781748 5451185 Xanthine Xanthine 8118156 8272256 5426721 6637688 4189880 6861037 Xanthosine Xanthosine 10036 Xanthylic acid XMP 263324 174593 135494 233982 217021 373686