Metabolite_name RefMet_name KR1M0 KR1M2 KR2M0 KR2M2 KR3M0 KR3M2 KR4M2 KR5M2 WT1M0 WT1M2 WT2M0 WT2M2 WT3M0 WT3M2 WT4M2 WT5M2 Factors - Genotype:KR Genotype:KR Genotype:KR Genotype:KR Genotype:KR Genotype:KR Genotype:KR Genotype:KR Genotype:WT Genotype:WT Genotype:WT Genotype:WT Genotype:WT Genotype:WT Genotype:WT Genotype:WT 2-Phosphoglyceric acid-m0 2-Phosphoglyceric acid 1623305 1080059 1939541 3276394 1251180 2788213 3085875 15198956 1258293 427564 391838 543124 1075535 1703916 6585807 2-Phosphoglyceric acid-m1 2-Phosphoglyceric acid 2-Phosphoglyceric acid-m2 2-Phosphoglyceric acid 2-Phosphoglyceric acid-m3 2-Phosphoglyceric acid 3-Phosphoglyceric acid-m0 3-Phosphoglyceric acid 2412072 735489 6348822 2835436 6262029 2166888 1886326 11640639 5995179 2043281 3297274 1722476 3805596 2554582 7471147 3-Phosphoglyceric acid-m1 3-Phosphoglyceric acid 3-Phosphoglyceric acid-m2 3-Phosphoglyceric acid 3-Phosphoglyceric acid-m3 3-Phosphoglyceric acid 6-Phosphogluconic acid-m0 6-Phosphogluconic acid 7377369 2566911 20887471 9302165 21345003 8749927 8331143 18237067 16075140 7783399 9210643 7672428 12739936 7741825 7443369 6-Phosphogluconic acid-m1 6-Phosphogluconic acid 2443465 512290 7869952 2721968 8071235 2630209 2576892 6983318 5406248 2153334 3397240 2505711 4952930 2205788 2492325 6-Phosphogluconic acid-m2 6-Phosphogluconic acid 12639338 5499956 36790607 18059878 37303003 18116408 17938724 29043339 28191513 14944876 17458354 14062890 20420081 15231187 13236158 6-Phosphogluconic acid-m3 6-Phosphogluconic acid 2292962 564089 7788074 2844319 8158631 2859628 2539824 7033385 5532190 2125249 3363169 1968136 4331142 2266549 2668649 6-Phosphogluconic acid-m4 6-Phosphogluconic acid 6-Phosphogluconic acid-m5 6-Phosphogluconic acid 6-Phosphogluconic acid-m6 6-Phosphogluconic acid cis-Aconitic acid-m0 cis-Aconitic acid 88625916 67589242 97293492 10098200 24694000 86972979 160956721 59833583 139916390 107430957 47888571 86522302 127233424 123069981 1922055 38327297 cis-Aconitic acid-m1 cis-Aconitic acid 24151910 14831734 28787388 2295938 6963409 23384906 39868906 19104606 34428869 22657483 7481888 19511255 31946434 25176442 7709965 cis-Aconitic acid-m2 cis-Aconitic acid 15864935 12003366 20505126 2063715 5111384 20339496 32160469 14140278 22331962 16690713 4038165 15805864 22603657 19139337 5203802 cis-Aconitic acid-m3 cis-Aconitic acid 6049041 3409344 7328368 521737 1563127 5395504 8536669 5316931 7936988 4945328 1500329 5739406 8734015 5256999 1969547 cis-Aconitic acid-m4 cis-Aconitic acid 25533363 23521100 34325286 4132112 8180367 42731480 70897413 21790191 36765084 30425906 7176327 26849782 30745240 35053524 8216971 cis-Aconitic acid-m5 cis-Aconitic acid 3329715 2229570 4747177 974192 1251400 4568052 6595399 4107891 5021185 3525645 651687 4475614 5988806 4176718 1737567 cis-Aconitic acid-m6 cis-Aconitic acid Citric acid-m0 Citric acid 2182657436 1991748473 4274753279 3175137425 3808480571 3670050554 4603495842 5171242696 4573096315 3926743634 3216584514 4102686128 3983173282 4577970762 151328196 4905156692 Citric acid-m1 Citric acid 472480386 378853809 924747194 619055332 851303534 734676259 896678598 1203728951 893738962 621420743 547795644 608051764 794600038 679404480 21376860 773643140 Citric acid-m2 Citric acid 300205768 271723523 618914101 446190149 580570397 543471213 659834786 854041940 537518186 400571270 325335716 381466250 505455797 407759984 11516752 445419314 Citric acid-m3 Citric acid 95668365 71139809 206523556 116527150 194248329 146323668 173422451 304968138 173139615 113573403 108380738 115921219 185444106 113363059 3131952 160202858 Citric acid-m4 Citric acid 489104750 519631584 999777294 829529140 935013834 1082227391 1314028167 1310145996 870225897 719286699 559916096 657607513 706825325 741086897 24168702 706663002 Citric acid-m5 Citric acid 70922724 55841059 156566454 91301223 151348343 111346747 143461573 243403111 133818186 94992436 93373911 96214539 146350665 89168945 2291147 143385512 Citric acid-m6 Citric acid Erythrose 4-phosphate-m0 Erythrose 4-phosphate 382331 445543 857938 1133846 1694996 1025728 1087513 799465 2611194 1044615 955337 798834 1342270 1536785 1064679 Erythrose 4-phosphate-m1 Erythrose 4-phosphate Erythrose 4-phosphate-m2 Erythrose 4-phosphate Erythrose 4-phosphate-m3 Erythrose 4-phosphate Erythrose 4-phosphate-m4 Erythrose 4-phosphate F16P-m0 Fructose 1,6-bisphosphate 15249711 7636153 1321945 1126255 1080685 2301592 504664 1606203 1695814 1443834 3402135 970998 1790298 F16P-m1 Fructose 1,6-bisphosphate F16P-m2 Fructose 1,6-bisphosphate F16P-m3 Fructose 1,6-bisphosphate F16P-m4 Fructose 1,6-bisphosphate F16P-m5 Fructose 1,6-bisphosphate F16P-m6 Fructose 1,6-bisphosphate Fructose 6-phosphate-m0 Fructose 6-phosphate 11369163 11058747 44852613 29866928 71782116 24810219 25272756 36768227 128673832 30181294 36522882 26015416 59970074 46579173 520147 49172957 Fructose 6-phosphate-m1 Fructose 6-phosphate 586708 632981 2813310 2043571 4704831 1409612 1606023 2199800 8873641 2030757 2591263 1623284 3944390 3178023 3069987 Fructose 6-phosphate-m2 Fructose 6-phosphate Fructose 6-phosphate-m3 Fructose 6-phosphate Fructose 6-phosphate-m4 Fructose 6-phosphate Fructose 6-phosphate-m5 Fructose 6-phosphate Fructose 6-phosphate-m6 Fructose 6-phosphate Fumaric acid-m0 Fumaric acid Fumaric acid-m1 Fumaric acid Fumaric acid-m2 Fumaric acid Fumaric acid-m3 Fumaric acid Fumaric acid-m4 Fumaric acid Glucose 6-phosphate-m0 Glucose 6-phosphate 13962590 15683800 51666436 64760828 93420350 54754424 68269496 57209338 147527978 51228726 50297913 47533549 70200901 93861021 1527716 58621931 Glucose 6-phosphate-m1 Glucose 6-phosphate 878978 1011783 3401483 4567770 6445615 3658819 4735519 4076992 10361238 3540794 3378671 3266509 4849647 6473097 46652 3783377 Glucose 6-phosphate-m2 Glucose 6-phosphate Glucose 6-phosphate-m3 Glucose 6-phosphate Glucose 6-phosphate-m4 Glucose 6-phosphate Glucose 6-phosphate-m5 Glucose 6-phosphate Glucose 6-phosphate-m6 Glucose 6-phosphate Glucose-m0 Glucose 985697 6044014 3653675 19807901 2265440 45764118 34784290 7909816 5246287 36878826 5146321 25890644 3183260 39369834 1052421 6122321 Glucose-m1 Glucose 161902 95054 983122 45170 2754547 1923476 160152 140539 2089293 46950 1243068 43094 2252253 131623 Glucose-m2 Glucose Glucose-m3 Glucose Glucose-m4 Glucose Glucose-m5 Glucose Glucose-m6 Glucose Glutamic acid-m0 Glutamic acid 1065784085 836138533 2444532210 2336663818 2500937191 1933570476 1707043003 2599744968 2185787330 1809687584 1875494906 1501281007 1972717032 2034601371 57797637 1965119603 Glutamic acid-m1 Glutamic acid 299352353 208377925 681541380 583832631 663964264 498967634 437231511 830276748 520685401 379418003 411778068 332722550 475017353 416129868 11607190 395288759 Glutamic acid-m2 Glutamic acid 124119699 92630205 284495759 252558098 286937162 222870358 196025131 377152496 210735873 156299464 163796013 139352084 201033343 175297179 4685077 168515549 Glutamic acid-m3 Glutamic acid 259943544 230485691 631833670 636524686 610353987 578014802 507895767 806815623 435623726 408591248 374479272 362694025 421311508 433127269 12342755 355680872 Glutamic acid-m4 Glutamic acid 41311881 34604375 92816744 89280066 83097459 84465255 72712370 111497608 60042620 51254575 51547856 44969039 49420305 58139815 1888233 48226561 Glutamic acid-m5 Glutamic acid 784538559 644764659 1736559506 1732388045 1535383858 1665232963 1404237643 2084403709 1098593954 935865406 992000924 792741225 876772152 1047677934 27140402 924901477 Glutamine-m0 Glutamine 29958252 25957718 114061448 92636213 130439699 110213874 108915208 154445369 138935433 243081114 96191699 190958628 103024335 307991029 6058334 185055303 Glutamine-m1 Glutamine 4542827 3132631 18008172 11846731 20081206 14613697 15179561 27535956 18335888 21624072 10848681 19131129 13916013 24528451 438157 17853270 Glutamine-m2 Glutamine 1550343 1067611 6720375 3815176 7701275 5485813 5302393 11633314 6133407 5684736 3271590 5406061 4582244 6091008 25059 5353429 Glutamine-m3 Glutamine 4482253 3580785 19059300 13084226 20188380 19198670 20251559 30113908 17681229 17504119 10255380 18481763 13074853 17080195 281188 13675305 Glutamine-m4 Glutamine 6595447 14922660 24312400 47285358 30452316 77159922 61671723 63496453 29478426 53407479 19683515 43352107 29328688 68560934 1755946 25988637 Glutamine-m5 Glutamine 150974791 351526977 571877902 1117094904 716999650 1857710776 1493967766 1505204140 689966398 1260141662 459772285 1022788469 698422836 1602956038 34971852 604747774 Glyceraldehyde-3-phosphate-m0 Glyceraldehyde 3-phosphate 3207989 14035806 141823730 75699075 131510966 66697743 76726607 154446889 160497401 4342788 66091818 5274695 64734961 44536862 136753610 Glyceraldehyde-3-phosphate-m1 Glyceraldehyde 3-phosphate 67612 396019 5186053 2620775 4766798 2353848 2484954 5709871 5867605 79404 2258474 104037 2222060 1470739 4747922 Glyceraldehyde-3-phosphate-m2 Glyceraldehyde 3-phosphate Glyceraldehyde-3-phosphate-m3 Glyceraldehyde 3-phosphate Isocitric acid -m0 Isocitric acid Isocitric acid -m1 Isocitric acid Isocitric acid -m2 Isocitric acid Isocitric acid -m3 Isocitric acid Isocitric acid -m4 Isocitric acid Isocitric acid -m5 Isocitric acid Isocitric acid -m6 Isocitric acid Lactic acid-m0 Lactic acid 164269820 261559332 662355266 846143723 481813464 901559003 751508986 617123077 632439573 1121684097 409976145 660986952 419761474 1336866199 49157372 652974680 Lactic acid-m1 Lactic acid 5869942 9448267 24421820 32132725 18201123 33525721 27216387 23309022 25460651 40672694 14004903 23963564 16441644 49861658 1257749 23782510 Lactic acid-m2 Lactic acid 837819 1902675 5076813 7438462 3990890 6508245 5507348 4731513 5457065 7691192 2363194 4591876 3211904 10797119 4895633 Lactic acid-m3 Lactic acid 1242329 2321526 4324701 5957145 4791903 4483067 5795215 4580875 5961663 3754991 2151586 4252394 3885066 7179345 3119986 Malic acid-m0 Malic acid 472818894 256197146 159529711 388596792 143307722 325434923 411815957 297884871 180243103 524364955 105583616 462659206 212090901 159425907 19481592 201950016 Malic acid-m1 Malic acid 132421265 62906184 42028007 94029890 39134663 82285135 100537043 92941215 41915102 107006113 21444170 89501221 50908617 32242529 3510105 38414610 Malic acid-m2 Malic acid 116948456 63837313 39596778 94434575 32080433 85600971 103556926 93303993 34199567 106170242 19157271 88353450 44994792 30619337 3295308 33380736 Malic acid-m3 Malic acid 29201617 16517395 9575108 20145795 9907744 19217698 20146594 20750850 6968677 21067904 6532838 19597260 12048018 6901694 8931326 Malic acid-m4 Malic acid 261474143 153099237 88655929 220669018 69851879 214421627 247831991 192987865 75030287 220705504 44559349 179429966 78662379 66191048 9938976 72795168 Oxoglutaric acid-m0 2-Oxoglutaric acid 22572491 8417671 15606089 8812484 20272706 7541530 11317630 11709374 17608380 5812652 12516721 4432989 17903242 6982616 3159800 10075843 Oxoglutaric acid-m1 2-Oxoglutaric acid 7209143 2745082 4822929 1623771 4981365 2437458 2093334 4173301 3839962 2886851 4423396 1536784 1929407 Oxoglutaric acid-m2 2-Oxoglutaric acid 2261218 850273 1789517 413941 1898596 640060 1477418 1483142 702385 1414738 717938 Oxoglutaric acid-m3 2-Oxoglutaric acid 5347510 2186280 4144959 2229347 4743987 2737119 3752378 3519075 3590208 1584183 2162725 6664548 3930029 2750344 608049 1789605 Oxoglutaric acid-m4 2-Oxoglutaric acid Oxoglutaric acid-m5 2-Oxoglutaric acid 19198572 8936605 12602018 7375058 12694347 8118120 9765375 9600838 8850695 4309227 7725061 3126798 8349153 4228966 2579062 5675991 Phenylalanine-d5 Phenylalanine 27983600 32443815 107012086 117024105 95198445 83979045 81510894 102119053 144281828 83823022 99678126 96042404 95936543 110400570 2795780 135025113 Phosphoenolpyruvic acid-m0 Phosphoenolpyruvic acid Phosphoenolpyruvic acid-m1 Phosphoenolpyruvic acid Phosphoenolpyruvic acid-m2 Phosphoenolpyruvic acid Phosphoenolpyruvic acid-m3 Phosphoenolpyruvic acid Pyruvic acid-m0 Pyruvic acid 3409340 5407137 15186844 13785931 14451074 12848654 12463126 13471370 14691939 11080795 8666526 9657389 12193502 14706471 12318509 Pyruvic acid-m1 Pyruvic acid 11896 48372 339391 299096 400460 153626 213122 237320 647748 155373 157607 466999 479549 216820 Pyruvic acid-m2 Pyruvic acid Pyruvic acid-m3 Pyruvic acid Ribose-5-phosphate -m0 Ribose 5-phosphate 4777623 1530089 4963083 2867027 6426248 2884110 2969308 3553792 8743766 3711091 3356647 3579697 5712602 4859298 10975 4927098 Ribose-5-phosphate -m1 Ribose 5-phosphate Ribose-5-phosphate -m2 Ribose 5-phosphate Ribose-5-phosphate -m3 Ribose 5-phosphate Ribose-5-phosphate -m4 Ribose 5-phosphate Ribose-5-phosphate -m5 Ribose 5-phosphate Ru5P/Xu5P-m0 Ribulose 5-phosphate 643583 1236399 1178177 1245821 1152959 1062225 1894612 574605 4364074 2196860 838286 2513496 1569694 2087139 63187 2862724 Ru5P/Xu5P-m1 Ribulose 5-phosphate Ru5P/Xu5P-m2 Ribulose 5-phosphate Ru5P/Xu5P-m3 Ribulose 5-phosphate Ru5P/Xu5P-m4 Ribulose 5-phosphate Ru5P/Xu5P-m5 Ribulose 5-phosphate Sedoheptulose 7-phosphate-m0 Sedoheptulose 7-phosphate 2118862 3243747 13418080 10568971 31647795 8272332 11556558 10540297 44788700 11887956 17047953 10219265 25858816 22179238 150953 5953749 Sedoheptulose 7-phosphate-m1 Sedoheptulose 7-phosphate 97404 174208 867712 596821 2124722 464482 783785 530779 3212562 913132 1099730 769657 1902012 1641356 195542 Sedoheptulose 7-phosphate-m2 Sedoheptulose 7-phosphate Sedoheptulose 7-phosphate-m3 Sedoheptulose 7-phosphate Sedoheptulose 7-phosphate-m4 Sedoheptulose 7-phosphate Sedoheptulose 7-phosphate-m5 Sedoheptulose 7-phosphate Sedoheptulose 7-phosphate-m6 Sedoheptulose 7-phosphate Sedoheptulose 7-phosphate-m7 Sedoheptulose 7-phosphate Succinic acid-m0 Succinic acid 8944300 19709144 16185689 34913413 13978646 39648448 99570817 15900436 25474759 30023804 14666185 61159110 11400138 31738646 8527467 12695700 Succinic acid-m1 Succinic acid 2062057 3069397 3098127 5157884 2819824 4716636 7602260 3606477 4074588 3048845 2289820 3910945 1881040 3109411 444172 1542081 Succinic acid-m2 Succinic acid 1756514 2983661 2347907 5506784 2546757 4426270 4664127 2459366 3724342 2354249 1831923 2230299 2084408 2526032 1176406 Succinic acid-m3 Succinic acid 169371 232846 176913 462009 242880 355285 382702 193129 182740 128205 91413 164201 76210 164589 46868 Succinic acid-m4 Succinic acid 15271829 20779730 14236927 25004624 16431745 24073043 21279856 15196299 14382571 15751682 13387438 13159633 11988503 14312651 10430163