Metabolite_name RefMet_name 314 318 319 321 322 311 312 316 320 serumPBQC_1 serumPBQC_2 serumPBQC_3 serumPBQC_5 serumPBQC_6 326 327 330 334 335 324 328 332 333 Factors - Treatment:Fasted/CSF1-Fc Treatment:Fasted/CSF1-Fc Treatment:Fasted/CSF1-Fc Treatment:Fasted/CSF1-Fc Treatment:Fasted/CSF1-Fc Treatment:Fasted/Saline Treatment:Fasted/Saline Treatment:Fasted/Saline Treatment:Fasted/Saline Treatment:Pooled Biological Quality Control Treatment:Pooled Biological Quality Control Treatment:Pooled Biological Quality Control Treatment:Pooled Biological Quality Control Treatment:Pooled Biological Quality Control Treatment:Unfasted/CSF1-Fc Treatment:Unfasted/CSF1-Fc Treatment:Unfasted/CSF1-Fc Treatment:Unfasted/CSF1-Fc Treatment:Unfasted/CSF1-Fc Treatment:Unfasted/Saline Treatment:Unfasted/Saline Treatment:Unfasted/Saline Treatment:Unfasted/Saline 1_5-Anhydrosorbitol_HMDB0002712 1,5-Anhydrosorbitol 114216 122183 124539 101124 175279 115859 167958 138393 144288 207075 173192 136457 123868 142735 127203 204971 144215 124251 98126 179383 119327 127917 142834 1-Hexadecanol_HMDB0003424 Cetyl alcohol 26587 34221 30727 33427 34267 36495 31251 31970 45237 56766 53217 39694 45220 41903 34653 41577 76745 38593 29596 49342 36624 96826 30436 2_3-Dihydroxybutanedioic acid_HMDB0059916 Camphene 6546 33578 36799 114081 30374 24563 23753 26050 40681 45683 47450 38627 32655 35841 46036 41729 65860 60436 27990 36337 31644 45314 51379 2-Aminoheptanedioic acid_HMDB0034252 2838895 4304917 3612763 3878796 5132221 2899881 3647492 3449767 6339815 5883783 5526337 4483747 3746914 4152842 3546951 5697239 5659969 4668650 4473504 4687329 2853387 2821021 2998810 2-Deoxyglucose_HMDB0062477 2-Deoxy-glucose 2296358 2197096 3749777 2731436 2264831 2614359 3543719 3455611 5630852 5116100 4718441 4049938 3364046 3730859 4075731 3984444 5043023 4877844 3392921 4052157 3035930 4032277 4493898 2-Hydroxy-3-methylbutyric acid_HMDB0000407 2-Hydroxy-3-methylbutyric acid 1293307 1237305 1207845 1307232 1459028 1479863 1852047 1806314 1497984 1404743 1331638 1109652 945808 1061974 531395 742917 618421 492618 544584 559194 437610 453641 392778 2-Hydroxybutyric acid_HMDB0000008 2-Hydroxybutyric acid 2695820 3574936 1330677 2306938 3132711 3329058 3431311 3647026 2442986 2568527 2356281 1995121 1764873 1888581 813767 1148789 969237 538852 621082 823719 518512 302353 414463 2-Ketobutyric acid_HMDB0000005 3-Methyl pyruvic acid 188551 177227 189314 168841 189370 172656 188826 195056 186760 268143 229205 212801 199313 202460 223664 237048 286667 219358 205455 257719 187892 228262 240350 2-Methyl-3-hydroxybutyric acid_HMDB0000354 2-Methyl-3-hydroxybutyric acid 17909 21193 13378 12184 21523 15554 20027 16853 34712 21645 19025 16333 16196 14969 12749 11967 14494 10592 10384 11927 6359 6247 6357 3-aminoglutaric acid_1 834086 3015747 1114295 4564226 742662 1748534 2389617 2703601 1514222 3541682 3146110 2600694 2428070 2667120 2968271 1291183 14827028 3828450 1641933 2095935 1381312 4905353 1245755 3-Hydroxybutyric acid_HMDB0000357 3-Hydroxybutyric acid 36716465 35934012 34429610 34863988 37606338 37532633 38495168 37981197 37616450 36017945 35400331 35038132 33883200 34200719 19329926 22657972 21949309 11685260 18241703 23979907 17309159 15541698 14776059 3-Hydroxyglutaric acid_HMDB0000428 3-Hydroxyglutaric acid 13554 18629 8975 10857 20574 29920 39972 32707 18403 20030 17472 14655 14321 15067 5661 6184 8127 6305 4916 6681 4052 5368 4120 3-Hydroxyisovaleric acid_HMDB0000754 3-Hydroxyisovaleric acid 530189 793855 452339 437355 874806 602466 944597 664374 1197127 711850 732949 537193 461278 529361 203840 372166 436062 337232 327759 244455 240318 228906 227857 3-Hydroxymethylglutaric acid_HMDB0000355 3-Hydroxymethylglutaric acid 13311 9935 6026 7694 17287 17005 22873 23546 12356 14643 14099 11006 10853 10757 4304 5594 6287 4851 6572 6597 3199 2312 5278 4-Hydroxybenzoic acid_HMDB0000500 4-Hydroxybenzoic acid 76334 122795 63118 177104 91354 135672 209297 217020 190172 211147 182012 148510 139018 150080 103216 118403 282895 100012 146937 163499 148714 189368 84776 4-Hydroxyphenylpyruvic acid_HMDB0000707 4-Hydroxyphenylpyruvic acid 717118 954051 695576 627361 957300 668373 847426 724019 944754 1146126 1083145 854646 707803 794563 946242 876701 1266839 819034 757545 852584 391259 524400 617640 4-Hydroxyproline_HMDB0000725 cis-4-Hydroxyproline 2656526 3581236 4660003 4988597 4655086 4121856 5215138 5233783 6794659 7392001 6200277 5199728 4910283 5298581 6119173 4426845 8823581 6893833 4546374 7753349 4747324 7660693 6343313 5-Aminopentanoic acid_HMDB0003355 5-Aminopentanoic acid 19451 40382 36936 82655 67620 29037 30263 33445 57531 46576 40866 35950 26234 28579 51916 40310 64538 46865 40562 27548 27166 40514 41041 5-Methoxytryptamine_HMDB0004095 5-Methoxytryptamine 226940 124396 255396 80917 332813 2207331 2705821 1739657 1716404 1704421 1641846 1177233 745291 561397 274553 459562 369042 234189 1977310 2065379 1089141 1048969 590540 5-Methoxytryptamine_HMDB0004095_b 5-Methoxytryptamine 227219 121041 260707 66967 338002 2281091 2780735 1785396 1772028 1786980 1699557 1207904 768174 787371 281010 466883 382936 223630 2025819 2147128 1102082 1092079 600772 Acetoacetic acid_HMDB0000060 Acetoacetic acid 39812 43610 32444 34102 55207 71086 39672 40327 34994 44367 42182 38914 43158 41617 37583 35598 32209 39406 30896 36314 36003 30182 35908 Acetoacetic acid_HMDB0000060_a Acetoacetic acid 59483 68334 54876 74822 90216 81357 69950 68727 68605 65719 64063 56056 66383 65779 61172 52578 52960 50434 45393 48785 49942 47769 48328 Acetoacetic acid_HMDB0000060_b Acetoacetic acid 1538577 1458157 1614247 1473327 1504639 1337458 1483913 1556548 1151791 1979160 1640335 1524935 1550447 1354455 1567282 1764464 1565875 1429861 1488129 1689836 1383010 1460476 1656938 Acetylglycine_HMDB0000532 N-Acetylglycine 471930 515575 503504 664350 727043 920129 808131 726659 1624124 595353 577461 509194 408329 466377 144143 248790 242517 226139 91444 156486 201630 189578 172443 Acetylglycine_HMDB0000532_b N-Acetylglycine 517567 264868 342571 313809 478787 435155 684189 746742 185693 515997 492787 350056 362448 407967 138028 211852 233968 166372 75479 208542 135303 110195 212203 Adipic acid_HMDB0000448 Adipic acid 22769 22833 12810 21597 18419 21441 21654 26904 23130 31421 24316 19967 16487 18720 19766 17012 19170 15994 17011 21091 11808 13221 13249 Allantoin_HMDB0000462 Allantoin 132756 141771 157112 206437 198657 136330 159795 166634 122249 265914 236306 192737 142754 149363 118414 254488 230477 168268 144698 171944 152152 160335 149001 Alpha-Hydroxyisobutyric acid_HMDB0000729 2-Hydroxyisobutyric acid 593691 430292 532016 549761 778451 977538 1138223 888279 1165296 790491 736463 623642 583353 620616 333983 441860 233961 266794 260926 452960 516867 481556 302870 Aminoadipic acid_HMDB0000510 Aminoadipic acid 73947 102380 92998 139162 110181 117114 128864 130931 130597 141213 125300 103281 92652 99201 148031 113685 167250 92242 57654 82231 64450 83071 83917 Arachidonic acid_HMDB0001043 Arachidonic acid 1204805 2265358 1713913 6038462 1794619 2490548 3153736 3864343 5255545 3197265 3585939 2982379 2717779 3316918 1496436 2279868 2417187 2228680 2406246 2028988 2603406 6997354 1936157 Benzoic acid_HMDB0001870 Benzoic acid 1911211 1595673 1501784 1864250 1946864 2136293 2215977 2253681 2191564 3461482 2241616 2069616 1882267 2011090 1944283 1919117 2027242 2072984 1832816 2223221 1879349 1818810 1971908 Beta-Alanine_HMDB0000056 beta-Alanine 438166 445273 398026 282452 508877 447153 570761 699942 99479 877438 770225 583602 528108 586179 645451 562543 1078781 435242 725653 713548 240324 300762 523871 Beta-Alanine_HMDB0000056_b beta-Alanine 31454 89882 50539 211937 79623 84841 95419 85723 104604 102299 97778 72533 56834 62597 45428 29274 261689 50802 70732 73896 43118 67398 23967 Beta-Glycerophosphoric acid_HMDB0002520 sn-Glycero-2-phosphate 46434 60352 54329 108937 52389 69029 87834 99428 97427 113582 99753 97906 86556 108636 89268 81151 165645 90922 78670 92270 91695 139540 79466 Capric acid_HMDB0000511 Capric acid 178087 203389 161413 184367 189158 217812 190726 235549 281670 263215 243762 186070 215526 261235 159383 238494 198815 210924 157153 204707 180747 287023 171868 Caproic acid_HMDB0000535 Caproic acid 674406 662554 631813 732834 676150 644403 652553 757283 1020992 779387 671687 673900 629645 705183 650020 737503 563380 581758 648707 589838 604575 632113 603461 Caprylic acid_HMDB0000482 Caprylic acid 276653 264429 251038 264033 294295 286326 289058 340143 361938 349641 297153 282738 283286 289450 276699 297834 264174 256750 273128 277270 250718 283204 258848 Cholesterol_HMDB0000067 Cholesterol 676743 1187585 1191508 4223480 1567373 778281 1230964 1532638 2059633 2220298 2307543 1817983 1383398 1665956 1291136 1998716 2419868 1610684 983153 1486011 1447215 2720280 1862270 cis-Aconitic acid_HMDB0000072 cis-Aconitic acid 40832 42438 40840 39465 63118 36447 51679 45398 65025 71036 66683 43575 38947 38930 38789 66507 59631 41308 51479 55448 30186 33827 42058 Citramalic acid_HMDB0000426 Citramalic acid 89682 132752 258753 66115 66324 72672 58474 56056 225318 363872 314930 277217 241713 268443 364597 822285 230037 252856 491182 656544 453347 357683 418066 Citric acid_HMDB0000094 Citric acid 3669568 5608052 4673490 4993454 6631295 3695231 4722881 4380530 8110988 7875109 7141592 5801255 4845032 5502130 4553908 7318777 7467487 6275483 5842029 5999960 3696873 3597334 3897065 Creatinine_HMDB0000562 Creatinine 359094 1026150 407752 204898 574238 615489 570939 458075 299513 430610 543243 344632 159009 239962 112542 287536 373388 546270 163574 139791 48513 326535 124010 Cytosine_HMDB0000630 Cytosine 39326 71516 41367 146424 50892 24308 21005 35467 37819 112356 55409 44941 44507 41187 46266 51603 59793 50088 23921 35308 18453 31882 42770 D-Alpha-aminobutyric acid_HMDB0000650 2R-Aminobutyric acid 95360 119514 116601 83825 136239 134890 170113 124669 90088 120840 112446 95049 94840 96362 63044 93228 80662 71056 46826 52933 34343 28790 67461 D-Arabinose_HMDB0029942 Arabinose 83896 54199 95640 114960 81545 79159 110927 120516 149338 185152 154707 113578 126888 126586 124364 150677 175909 126938 145872 208089 218528 184969 139836 D-Arabitol_HMDB0000568 Arabitol 28179 20563 22488 34775 21985 15495 25136 24495 27525 54565 42207 41183 31040 30207 50749 53938 61184 41290 27387 50106 28970 42838 42508 D-Erythrose 4-phosphate_HMDB0001321 Erythrose 4-phosphate 47612 22621 51531 44309 42851 41053 49820 44826 58071 80232 62732 77251 67311 69753 75146 79624 75824 69430 59951 81062 82063 88574 58830 D-Fructose_HMDB0000660 Fructose 12964925 4785030 16398699 5419398 6821319 8503582 11855380 10375304 17952109 24778343 23944388 22970688 21109592 22192406 21370430 26187538 26305673 22777705 26622622 28651096 28616231 28139200 26247909 D-Fucose_HMDB0029196 D-Fucose 40025 33038 38164 54002 49049 38280 39733 54631 49085 56786 48287 43306 36217 43532 24180 48915 32030 32030 31614 32837 21915 55346 25887 D-Fucose_HMDB0029196_b D-Fucose 138813 131685 150236 153040 174759 121003 147062 191651 177475 190893 176431 140145 119454 130878 90147 146207 128015 121253 102761 106944 84520 116835 90056 D-Galactose_HMDB0000143 Galactose 4477776 2241417 5510130 3260066 3706638 3517209 4739323 4198618 5920094 11793614 9842576 8273843 6505502 7242263 5165158 13218955 10621777 8434776 10140498 14597536 18687302 15085518 12197366 D-Glucose_HMDB0000122 Glucose 26801859 22237142 28504411 25262575 25567930 27633972 29352017 27857450 30298905 33835864 33142727 31617125 30904109 31413205 31299626 33380741 34453505 31556630 32737110 35079183 34463829 35385404 32806094 D-Glucose_HMDB0000122_b Glucose 36154344 33235181 37427190 34930635 35292518 36652400 37484073 36859481 38926628 41521517 40767232 39639314 39859259 39817036 39146313 41197465 42060198 39189041 40094547 42462436 41812445 42600481 40146973 Dihydrouracil_HMDB0000076 Dihydrouracil 71598 231343 81916 21399 62399 76308 88517 49753 108080 141977 147982 101512 112599 117435 28899 127698 19333 153680 319952 137771 87350 55306 120467 Dihydroxyacetone phosphate_HMDB0001473 Dihydroxyacetone phosphate 648106 528327 609022 2514808 1091269 1239670 1976377 1921830 1329615 2633633 2292041 1633898 806179 947082 573291 1659985 4766514 926452 1435628 2029644 752202 2750051 1337639 Dimethylglycine_HMDB0000092 Dimethylglycine 294026 406648 361226 482378 422454 303038 280759 322403 510289 482878 397297 368056 370835 378593 484328 403559 621992 508332 301895 334196 283524 356182 366678 D-Mannose_HMDB0000169 Mannose 297971 168107 483627 174859 205302 220951 241278 224260 458245 1396740 1065585 971745 841185 906797 878602 1888918 1852596 1294680 1790776 3197131 5504595 2863098 2251471 Docosahexaenoic acid_HMDB0002183 Docosahexaenoic acid 161296 197762 206035 566251 231671 296830 371132 413006 471627 268349 347694 349861 314060 353007 125743 245783 246659 193407 177091 165928 255128 445234 187209 Dodecanoic acid_HMDB0000638 Lauric acid 177341 236228 132308 242848 146916 174034 219772 148400 274848 194936 214558 138814 205308 317404 112503 143520 131995 201159 109582 89345 207561 194695 93316 Dopamine_HMDB0000073 Dopamine 143880 604760 288037 1262462 456748 378265 236594 368335 350516 482826 398834 344121 273541 282589 581624 313634 672639 371059 263539 217162 121297 341494 223108 Dopamine_HMDB0000073_b Dopamine 15993 21921 32161 33216 51473 24034 31227 26614 38144 10959 12574 18751 21084 19082 19370 1137 33868 17976 920 10358 29668 16287 29233 D-Ribose_HMDB0000283 Ribose 49732 32665 52851 52373 56308 65810 76185 76262 82562 124108 112514 88330 84919 89684 61195 101561 108925 82920 116818 143786 146095 138453 82055 D-Tagatose_HMDB0003418 D-Tagatose 298472 308761 373693 268811 412266 296077 399251 354024 543100 721807 603798 511436 432739 455068 539989 691426 789253 621398 467939 796696 845595 748517 693912 D-Threitol_HMDB0004136 Threitol 11898 11718 10721 10390 12739 9877 19539 18625 15306 15934 16735 14127 14834 19806 29018 16615 22103 19504 15056 18780 12121 9225 18886 D-Xylitol_HMDB0002917 Xylitol 28626 41637 53454 68563 60680 37397 54631 52281 80553 117382 90945 73450 60867 61963 99781 85716 185995 110910 51401 87921 54887 83479 143273 D-Xylulose_HMDB0001644 L-Ribulose 238904 83453 219746 100683 244474 202229 271616 284433 304119 471526 434401 345505 291794 308759 250064 340920 373777 230203 356126 492383 427073 533940 265196 Eicosapentaenoic acid_HMDB0001999 Eicosapentaenoic acid 145460 220605 63408 199725 80325 275758 145837 402023 213814 456635 509014 174270 153092 494588 289317 465470 573294 432403 224045 511161 528841 983071 392777 Elaidic acid_HMDB0000573 Elaidic acid 439313 510935 357088 1059907 705555 477228 617585 592432 1102701 907997 881037 697202 634451 713024 441001 815597 1194070 881004 491647 705071 472042 1126574 595430 Erythritol_HMDB0002994 Erythritol 20675 22720 30443 26272 25745 21732 33095 30027 38668 44268 44527 38232 34332 37499 37247 46410 44007 37961 29025 39730 29902 37194 33030 Ethanolamine_HMDB0000149 Ethanolamine 79926 82467 101532 81507 105085 77514 111929 121272 37820 166825 109489 127379 112492 117199 128664 111682 186122 105727 132576 111171 116540 100238 88851 Ethanolamine_HMDB0000149_b Ethanolamine 429284 735990 664528 1227177 873636 487798 645345 671828 493518 1240188 772687 807157 596493 643285 626652 616927 1424446 666529 692897 567703 597737 816280 353469 Fumaric acid_HMDB0000134 Fumaric acid 120652 233467 150900 188391 128869 198906 235875 223292 558163 461318 415205 319513 311672 331347 240109 244850 836971 335886 600474 615528 246545 349790 148945 Galacturonic acid_HMDB0002545 Galacturonic acid 518042 500733 731641 796139 588104 780533 1111362 913289 1678130 1746008 1643249 1238348 989739 1074919 1413329 989228 3694250 1465326 640403 1226595 939233 1023600 2732579 Gamma-Aminobutyric acid_HMDB0000112 gamma-Aminobutyric acid 17240 37550 13395 96635 30917 30074 29059 39083 14848 41210 28119 26063 20334 24731 18818 17217 74170 19395 34685 13902 18896 21774 9453 Glucaric acid_HMDB0000663 Glucaric acid 27276 24027 27808 75222 38348 33450 45910 44512 51490 77230 68844 58982 52457 54495 94707 46411 144730 78606 35310 75996 46791 68444 98823 Gluconic acid_HMDB0000625 Gluconic acid 152972 84584 153309 311786 371146 186332 212956 233417 297515 420052 519735 292143 234279 248239 272462 421596 521800 287367 562410 511187 565889 596385 436763 Gluconolactone_HMDB0000150 Gluconolactone 345137 201977 515210 240038 258476 247384 322518 304858 621660 1532369 1216605 1091108 971259 1091284 1059868 2070639 2139787 1590906 1944229 3475706 6052434 3145022 2475053 Glucosamine_HMDB0001514 Glucosamine 823981 409471 1069639 614916 763391 792998 1064044 916772 1112583 2152277 1894817 1533525 1225390 1351490 1275141 1961859 2097512 1284224 1528557 2388785 1943075 2052353 1915514 Glutaric acid_HMDB0000661 Glutaric acid 44019 62315 31474 160542 53013 61983 82300 75800 91485 98234 87693 70416 63594 65374 71440 54923 60614 56376 78428 92518 44464 45274 37058 Glyceraldehyde_HMDB0001051 Glyceraldehyde 14038 9185 7717 9148 13999 12854 15586 14669 15315 22254 17801 17793 15885 18380 17424 22454 17245 16917 15447 24128 22681 22896 21251 Glyceric acid_HMDB0000139 Glyceric acid 17897409 21124043 22529516 21420760 19025850 17697519 19361419 19629018 23204149 26202764 25541112 24428364 23408866 23799347 25312452 26325629 27394652 26896182 24287099 26170490 25738086 26257459 27140136 Glycerol 1-octadecanoate_HMDB0031075 7129 2814 116810 63265 3884 101476 17311 21801 68615 24888 8327 7401 22181 209404 18331 7737 704 11135 3753 171021 27261 66521 168782 Glycerol 3-phosphate_HMDB0000126 sn-Glycero-3-phosphate 1362328 1132943 1277014 5458897 2266556 2619231 4301807 4218145 2818585 5772217 4943170 3514917 1785930 1986078 1226843 3674680 10456116 2036645 3004751 4368815 1637248 5855697 2902251 Glycerol_HMDB0000131 Glycerol 5368293 9494286 3302976 16657925 6032064 5713686 5394567 7073786 6313783 8435234 7232374 6468849 6288477 7105004 4607171 5390386 7952192 7152252 3492409 5049130 3825774 9881101 3746218 Glycine_HMDB0000123 Glycine 2541023 1899351 2930445 1887189 2392402 2517416 3363128 2875726 2001585 5837149 4102099 4266275 4334935 4395961 6748041 4858711 8198702 6011772 3952521 5281398 3491259 5201175 5942548 Glycine_HMDB0000123_b Glycine 9083589 15917289 15420109 21256565 22477509 12880080 10626151 9500081 20819068 20919805 21608259 17763080 14840065 15231880 20499183 19612151 25600261 23409781 16668457 15338214 14732261 23037637 20019705 Glycolic acid_HMDB0000115 Glycolic acid 3617890 5042510 4841587 5953160 4125153 4606955 5353070 6008509 7516439 8971378 8355869 7160237 6506001 7028552 7773531 7346015 10315867 8736313 8562700 8943319 8723316 8171308 8401706 Glycyl-glycine_HMDB0011733 Gly-Gly 8365 28366 16670 46469 24533 19816 20075 22857 9917 33583 27751 16550 18202 18316 31847 19408 63627 33243 15160 11530 6077 21405 14818 Glyoxylic acid_HMDB0000119 Glyoxylic acid 314981 432857 385894 502493 449316 316550 292371 338140 538704 509327 411280 385040 390836 402439 516305 420519 659616 558072 307940 339629 298981 376134 391972 Hippuric acid_HMDB0000714 Hippuric acid 214371 233364 249110 197068 313789 233607 328354 290972 308562 465577 375998 308961 270405 293056 290680 426494 333641 287259 224687 420370 366437 308765 312029 Homocysteine_HMDB0000742 Homocysteine 40791 43604 73096 80008 69068 62402 76014 71350 65951 80930 76583 70884 78412 83868 83054 81121 71446 92568 58189 62192 54067 79324 63348 Hydroquinone_HMDB0002434 Hydroquinone 6589 10980 8926 9879 10934 8412 10926 10492 10076 14607 9814 10555 17923 13227 16665 12120 9814 26296 12863 11535 24008 14729 11087 Hydroxylamine_HMDB0003338 Hydroxylamine 21268283 25029185 21521456 25482311 25954371 20740213 21627162 22794339 17338823 26358192 22606434 21967778 20184584 17813364 21265437 22249154 26332618 23393279 21142781 21718869 18813547 24521094 21335282 Hydroxypropionic acid_HMDB0000700 Hydroxypropionic acid 2269126 4063884 3669234 3769793 2657310 3221919 3901584 3588029 5456606 6822763 6950696 6071459 6031915 6556444 7247171 7360322 10703802 9976994 6781302 8304818 9665059 9560486 9389121 Hydroxypyruvic acid_HMDB0001352 Hydroxypyruvic acid 3693 5063 3577 8204 5167 4691 4044 4944 7206 7355 7314 4343 6657 6056 11276 6495 10654 10217 6974 7955 7150 8261 8632 Hypoxanthine_HMDB0000157 Hypoxanthine 2727 2874 2871 95420 1268023 759437 1007733 2116406 204345 476711 419834 343378 255415 243314 2796 6856 7103 160836 32558 3298 5707 164720 30988 Indoleacetic acid_HMDB0000197 Indoleacetic acid 108582 114073 196887 110183 146045 272421 319216 279883 496920 448020 439872 346926 293584 329372 218547 272564 378650 190239 693391 428677 330320 250928 252552 Isocitric acid_HMDB0000193 Isocitric acid 179254 280572 207252 284472 266644 150186 198039 191037 315214 342953 313761 239922 206603 246023 187591 312878 338396 296543 230154 206546 144945 170936 192203 Itaconic acid_HMDB0002092 Itaconic acid 9545 11341 9764 10223 9436 5941 10146 10844 19951 37917 21100 13794 9273 14186 11669 23381 28219 15428 17113 32251 14213 10356 14282 ITSD_Sorbitol 4920365 5163806 6012035 4331141 5822281 5075593 6349663 5957317 7333400 9496531 8562142 6777098 5525474 5985834 5315821 7588399 7494968 5770328 6114447 7680742 5652349 6758311 7016757 ITSD_Valine 10059678 12691990 11240034 10828594 12791750 10551294 13490789 13510183 7562922 15665877 13530694 11102339 9963146 10685370 9632971 10693753 10567672 9216628 9218379 10618806 7589009 8074607 9816946 L-2-Hydroxyglutaric acid_HMDB0000694 2-Hydroxyglutaric acid 128020 256856 109143 157369 157274 149017 187430 182631 250591 316379 283090 227650 207479 220173 245645 231212 455843 270235 318761 345068 155587 214642 190689 Lactitol_HMDB0040937 Lactitol 78617 49939 68076 82199 70051 69703 124297 77473 109788 1316346 1299243 917764 747244 849680 340329 255251 30099914 252388 143540 304525 182241 361916 214006 L-Alanine_HMDB0000161 Alanine 1220374 1548989 2622269 1585188 1712237 1639511 1967144 1537967 2610396 5374454 4772499 3943144 3736329 4072645 6468742 5399296 10001707 6337175 3232822 6425566 3492762 5226540 5301990 L-Arginine_HMDB0000517 Arginine 491884 470999 686891 640031 1196781 737719 857342 573819 920740 904258 899905 748131 590007 742662 519109 973721 595645 702773 839876 771553 577773 607240 584643 L-Asparagine_HMDB0000168 Asparagine 355286 528795 780552 634944 996159 754904 855466 571658 1202661 996882 1005762 772388 721958 714352 956905 1163970 840645 1055291 995566 1057660 515616 1403745 1088693 L-Aspartic acid_HMDB0000191 Aspartic acid 790722 2936964 1102602 4484241 753885 1716169 2349704 2695737 1519961 3495327 3114405 2516607 2430085 2595011 2901700 1299055 14761744 3775996 1618115 2092933 1340919 4877482 1260622 L-Cysteine_HMDB0000574 Cysteine 3963329 4835496 5750832 4350260 4624297 3967086 4598485 4236029 6625197 8340443 7226604 6239850 5122170 5448643 5448656 6587778 13521986 7862420 3045139 4831284 3922138 5802640 6878575 L-Erythrulose_HMDB0006293 Erythrulose 24032 10101 23075 19068 23786 17417 20569 10931 32110 61719 57686 42157 37595 42145 46022 60939 66362 45815 37476 71979 51439 68776 51586 Levoglucosan_HMDB0000640 Glucosan 112781 144347 130376 191715 153042 132208 128398 147250 195269 272058 224299 177622 198803 192189 213757 192057 437196 279559 135405 212033 147237 201883 234300 L-Glutamic acid_HMDB0000148 Glutamic acid 369260 876994 317158 784547 327452 513130 669800 858599 498053 930798 865638 685370 642165 698273 817950 519811 3261020 1074790 553261 446253 363587 1070091 389054 L-Glutamine_HMDB0000641 Glutamine 318964 162409 533627 443497 573956 289115 668853 583728 108756 1125615 895295 515732 537717 627940 645185 857691 485894 619257 695086 797538 336660 680528 1183175 L-Glutamine_HMDB0000641_b Glutamine 1619649 1597139 3568442 5117954 6001926 5160269 7430483 5401670 4266127 6511794 7633493 4611247 3893957 4222272 3829031 6821784 5683375 4207986 6534469 4628987 2250973 6574959 7322765 L-Histidine_HMDB0000177 Histidine 61863 35400 159707 110991 435062 273503 348925 192502 166441 325728 510371 299314 140824 98722 75704 394548 738296 113561 396428 234745 37383 532742 263966 L-Homoserine_HMDB0000719 Homoserine 3213 3487 4450 5511 5615 1868 4399 2757 3178 5764 5593 5370 4357 5741 7711 7701 8717 7855 4912 5118 4408 4568 7485 Linoleic acid_HMDB0000673 Linoleic acid 2512385 3185092 2332530 11699653 3562128 3291544 4218260 4450012 6811432 5232323 5444997 4423223 4281924 5744175 3571247 3505875 5765939 3765147 2438569 4375858 4228025 10390294 3293620 L-Isoleucine_HMDB0000172 Isoleucine 19062636 22327173 21986934 23836772 22939335 22422828 23276140 22204495 21507750 23050875 22312250 20375173 19501991 20270795 17193133 18819942 17479874 17644469 16232401 19337659 14727937 17091440 16268521 L-Kynurenine_HMDB0000684 Kynurenine 1948401 2642367 2500121 2557299 2745571 1997643 2960678 3016446 3742246 4201488 3694970 3087845 2467168 2770170 2823568 2789758 4754307 3942593 2034108 3181924 1811202 5020447 2646252 L-Lactic acid_HMDB0000190 Lactic acid 7403671 10618291 8482337 11353738 9668155 13431187 13590563 13564477 17636048 17735377 17028835 14960305 14961852 15747917 14091808 18808817 18654846 13655003 15992993 19813725 15667371 16422251 9643051 L-Leucine_HMDB0000687 Leucine 25606883 28519319 27582663 30224908 28568083 28534822 29052105 28326952 27084512 28953737 28376734 27100530 26665950 27230597 24556477 26806800 26483745 26095234 23323440 26018446 23736201 25192910 24377422 L-Lysine_HMDB0000182 Lysine 479525 1210728 852131 1650361 2158195 1115305 1020041 788319 1466000 1070106 918674 710921 599424 587862 867570 1015454 1189461 729436 401212 426880 242223 482885 512936 L-Lysine_HMDB0000182_b Lysine 10911 10686 21469 11461 23210 14717 29924 20072 24239 19696 14423 13279 19001 16432 23406 21261 18539 15172 11127 11667 4645 11894 15726 L-Methionine_HMDB0000696 Methionine 3970 4804 4969 7509 17813 7547 3883 3299 5072 9388 7964 6384 4259 7136 10680 14105 11218 5316 6114 5931 6591 8046 5917 L-Phenylalanine_HMDB0000159 Phenylalanine 4495478 7307076 5683004 9417477 6856591 5564765 6274852 6162203 9517759 8618984 8049761 6136004 5711147 6305827 7019813 6552327 6553194 5901564 7259489 5448474 3535651 5624649 5194001 L-Proline_HMDB0000162 Proline 23664891 25479557 27243025 26894207 27300336 23323445 24695057 23748833 24190014 30134361 29092344 28038772 27503512 28058144 31910519 28669648 32005862 30422276 27508304 29318971 23831130 28445343 30154354 L-Serine_HMDB0000187 Serine 7987673 11245096 13570284 14058855 15462222 15695088 18322441 13620045 20879334 21815324 20611199 19426255 18171754 19037217 22024948 20264019 22853255 21764510 18991538 22084642 18075272 22127297 21905917 L-Threonine_HMDB0000167 Threonine 8408848 6556804 14218137 11708304 15062940 9688334 12026064 9042783 15054192 17366508 15594184 13367319 12331995 13257074 18595122 17187841 17817774 16403782 8595821 14623317 7467078 12252086 18286087 L-Tryptophan_HMDB0000929 Tryptophan 5462548 3366288 5962485 4159766 8275645 16771944 19147157 17019669 11097406 16839456 16380744 12559914 9110915 10509990 9497340 15415990 10429915 5689181 17572638 16265274 9246153 10186910 10352696 L-Tyrosine_HMDB0000158 Tyrosine 13924041 18920160 15451727 15739125 17493259 15277073 15126801 12291719 20360665 22013794 20758915 19118971 17892449 18762522 22499815 21346340 21284820 20994699 22376303 20114878 12716431 20230867 19072185 L-Valine_HMDB0000883 Valine 26752925 27778170 27641854 28961926 28857710 28617611 29545658 28641616 27736331 29968312 28862275 28134047 27053255 27496943 27482136 27265515 27189216 26351001 26311891 27297525 24605438 26169550 26434374 Lyxose_1 Lyxose 123295 96163 135816 97035 115904 133038 134797 79729 174449 492200 225321 199865 161659 204045 292196 352180 429157 310573 222259 456518 303169 371016 300015 Maleic acid_HMDB0000176 Maleic acid 19447 32102 34094 35825 35552 21511 23592 20775 23314 59788 50261 40572 35246 42211 83371 52346 80944 63724 41724 50951 20864 43921 56823 Malic acid_HMDB0000744 Malic acid 45504 113263 62585 85895 51390 84957 105152 103456 278254 235849 221827 166029 153938 166339 120752 124121 548749 197851 322077 314126 120293 181161 81546 Mannose 6-phosphate_HMDB0001078 Mannose 6-phosphate 207532 116617 249417 145049 253203 222903 265407 208477 375889 457720 435975 315818 273703 300100 198109 333920 503361 230615 211215 415195 216744 476709 243170 Mesaconic acid_HMDB0000749 Mesaconic acid 16120 17543 25727 14566 15967 11953 15450 15574 26093 63659 36387 27781 23313 24928 30109 77500 35289 24642 40432 68803 38555 32048 39242 Methylmalonic acid_HMDB0000202 Methylmalonic acid 5487 8375 8250 4656 5892 5775 7181 7289 10656 13172 9445 7231 8393 8457 9073 9518 7251 7892 8088 9360 5278 4353 7526 Methylsuccinic acid_HMDB0001844 Methylsuccinic acid 8262 15638 26783 7503 6595 3543 4766 4426 24402 36655 32238 22045 19892 24348 37269 94877 22179 20487 39254 47222 25305 23982 30991 MG(18:0e/0:0/0:0)_HMDB0011143 MG O-18:0 67176 108217 75020 215479 97483 138142 148777 168440 203981 215414 170396 145621 140078 180551 113542 146104 144904 121206 118996 152185 152729 218988 117316 myo-Inositol_HMDB0000211 Myo-inositol 4337368 5961466 5671904 5721923 6181297 4495944 6764950 6802094 8478397 9780249 8480912 7090949 5589032 6236029 6344368 6254504 11149291 8993356 4508960 7406754 3950716 11632604 6031361 Myristic acid_HMDB0000806 Myristic acid 604088 994069 329142 850470 785653 557693 722466 614290 801840 784279 789278 575090 590691 771400 264633 424803 606396 728953 270750 368714 407613 1119940 325726 N6-Acetyl-L-lysine_HMDB0000206 N6-Acetyllysine 69091 103846 139133 138452 175111 114870 123882 110851 144076 167433 180964 148736 131895 162887 183076 185757 186159 172802 133786 145871 133199 164779 158023 N-Acetylglutamine_HMDB0006029 N-Acetylglutamine 6043415 3822116 7295275 5510437 4994344 6408539 7639210 6614841 9298371 12149571 11803063 10649886 10461352 10946533 10535422 12285262 13197422 10581859 11366818 13766599 13483043 13801109 11473939 N-Acetyl-L-alanine_HMDB0000766 N-Acetylalanine 35624 59024 66147 61254 59704 59138 50545 52618 127637 98929 99740 75351 68688 73363 112987 102541 133852 121220 63269 90649 61079 85006 99889 N-Acetyl-L-alanine_HMDB0000766(2) N-Acetylalanine 25373873 28312767 27454902 29996516 28362700 28322182 28861404 27997721 26840329 28746820 28136869 26948982 26450735 26947704 24243287 26504698 26267337 25767020 23105838 25843036 23356027 24939635 24151372 N-Acetyl-L-methionine_HMDB0011745 N-Acetylmethionine 242940 768752 411515 949959 418137 835496 664464 616976 420965 608257 611446 514603 482635 475708 270999 328282 1366700 660816 328045 292987 285396 723707 139756 N-Acetyl-L-tyrosine_HMDB0000866 N-Acetyltyrosine 8390 18500 11685 10338 13616 6509 7157 5471 21190 19411 21385 12105 9817 14904 22297 19501 14510 25461 18762 13934 6481 14257 13136 N-Acetylserine_HMDB0002931 N-Acetylserine 16887 32713 32736 35776 33898 28392 33354 30153 57144 45880 47561 37839 36464 36885 55931 35995 58087 61812 27429 41016 21208 39364 50375 N-Formyl-L-Methionin_HMDB0001015 344941 1122272 589089 1351402 603006 1204203 948600 874410 605060 873584 855553 762226 695193 717332 394149 475785 1953451 940005 467517 430408 420649 1016020 195325 Niacinamide_HMDB0001406 Niacinamide 198398 551287 382027 685575 227560 294654 384902 381835 721836 808242 773979 614308 516888 599033 405270 508809 3084439 982470 247529 616277 467405 726490 672973 Nicotinic acid_HMDB0001488 Nicotinic acid 12369 9596 10693 16965 12534 8952 9847 12662 18244 42842 21648 18850 17336 16058 28040 23479 54399 21478 26397 32566 20060 23408 26806 Norvaline_HMDB0013716 Norvaline 24250 26775 30349 44414 45141 59846 49811 33339 64120 64650 64359 56034 44863 51143 55635 44359 54190 41253 57692 55901 20904 36774 48947 Oleic acid_HMDB0000207 Oleic acid 6882218 9012481 5320938 20372368 11009935 7735065 10189281 10788394 15987975 13294633 13125048 10592149 9212304 11332747 5815532 8568615 14460304 9896193 3842282 8069811 6153731 18103600 6948743 O-Phosphoethanolamine_HMDB0000224 Phosphoethanolamine 90180 344026 117420 303990 130495 153581 199425 194037 174858 217481 225718 172662 188292 203926 112463 146018 978988 290199 92612 107310 77355 249383 124992 Ornithine_HMDB0000214 Ornithine 966467 556685 1139292 982773 2452208 965128 2103426 1354869 1417679 1396917 1296073 1159530 1147784 1125406 1065399 1394301 765710 901013 1695272 1392651 668868 1134616 1174481 Ornithine_HMDB0000214_b Ornithine 2213953 10417954 4269518 17980437 7763135 6440374 3755846 5872917 5414144 7387721 6253021 4983178 4181320 4181290 9748179 4436223 10177635 5168120 3659092 2740614 1074725 4749595 3250604 Orotic acid_HMDB0000226 Orotic acid 54446 65867 78132 76772 82371 30938 34396 37542 50805 72158 62719 52821 44294 48424 36638 65003 48879 57906 30152 33004 18862 29197 37775 Oxalic acid_HMDB0002329 Oxalic acid 972797 1535131 1238043 1507667 1663481 1345775 1229144 1187033 1212277 1539272 1553703 1195601 966656 1188036 1442813 1712172 2677173 1671808 1135624 1249527 1120561 1524792 1460514 Palmitic acid_HMDB0000220 Palmitic acid 21306966 21870528 20317404 26037741 23649516 23307743 25126622 25110287 26410783 25355445 24788810 23683640 23269243 23784216 20377446 23582631 24340125 22189261 20807961 23604383 22561473 25793674 22399169 Palmitoleic acid_HMDB0003229 Palmitoleic acid 1228989 2096428 409842 1573872 1798877 1178893 1373191 1244587 1264470 1684238 1569961 1174710 1018164 1147340 200978 975903 1314512 1553545 251037 610729 602170 2684186 500366 Pantothenic acid_HMDB0000210 Pantothenic acid 48582 84856 75125 82326 73995 43336 69339 61203 81481 97082 99198 75343 63961 67974 86505 76057 112607 83236 71940 62623 42354 95798 51428 Pelargonic acid_HMDB0000847 Pelargonic acid 712311 701070 610655 627546 768134 800259 683520 872968 1012771 775655 712037 601460 775866 836586 905744 1054027 814188 747811 649296 866667 841516 847303 699479 Phenylacetic acid_HMDB0000209 Phenylacetic acid 129397 271534 126984 235504 238157 222336 219200 191171 435634 211948 192740 156702 140631 152264 124664 112201 110153 92657 127991 83655 64979 85173 82969 Phenyllactic acid_HMDB0000779 Phenyllactic acid 36862 42285 35317 35094 41959 43446 52873 51569 64523 51850 52395 39343 35694 39339 37943 36721 42743 28608 34651 30504 16961 17118 20876 Phosphoric acid_HMDB0002142 Phosphoric acid 26537050 32522469 30323185 42628202 30072735 28370017 31913989 31710093 32977420 37180569 35971158 33278318 29666892 31148228 26089105 33663389 36201901 33111165 29166250 34680211 26508028 35394856 35324872 p-Hydroxyphenylacetic acid_HMDB0000020 4-Hydroxyphenylacetic acid 14949 26835 16758 30875 27175 19707 24133 22139 34300 30311 30207 18205 17903 21851 41461 21032 27917 25627 26314 16134 11066 13067 20606 p-Octopamine_HMDB0004825 Octopamine 32380 111258 71596 171377 70518 95363 93539 88280 140944 81328 93856 66684 70597 67839 90781 53046 120925 153325 56143 57221 41186 132853 73006 Psicose_1 Psicose 426456 274233 683809 214731 227640 250355 338932 305769 643306 1814123 1423370 1245454 1075493 1179969 1096339 2371397 2128544 1639349 2274180 3922515 5501658 3465499 2721480 Psicose_2 Psicose 1163510 643765 1440681 441305 478222 415079 661000 604775 1333805 4088162 2876118 2973620 2325392 2448740 2546395 5441021 4960349 3956845 5850239 9405449 13632352 8417657 6499667 Pyridoxal_HMDB0001545 Pyridoxal 50633 46906 61531 41631 62800 46617 57781 54688 93041 121727 96746 79184 75464 81037 91196 122396 133259 103191 88337 140085 168984 134654 129598 Pyroglutamic acid_HMDB0000267 Pyroglutamic acid 24836663 30559102 28543927 32890056 27953072 28426210 29604130 30428561 31590551 31339259 28323243 28492283 28536355 28737249 28188109 26829602 31913628 31755048 26945788 26297408 24190238 30140940 27884405 Pyruvic acid_HMDB0000243 Pyruvic acid 14336 20890 18819 32889 17386 14574 16569 16179 19823 23057 21355 17819 18827 22478 22936 18522 25628 28073 14840 18696 14318 18639 15144 Pyruvic acid_HMDB0000243_b Pyruvic acid 51130 79079 76159 89259 63850 40114 39333 46720 53526 97396 70023 78737 75911 70195 133666 130630 121417 100182 79125 100963 91424 86173 95989 Quinolinic acid_HMDB0000232 Quinolinic acid 2986 3723 3240 9471 4652 6163 5901 5908 13358 10050 8906 4917 4586 4818 8560 3790 7236 4082 2484 9332 3283 3814 3824 Ribitol_HMDB0000508 Ribitol 32573 32493 39205 33864 53263 40523 65021 67171 37999 79928 64989 43203 45916 47206 47745 56743 52374 48427 41559 58104 26883 41067 63934 Ribonic acid_HMDB0000867 Ribonic acid 1343255 1669820 2483206 1827659 1311822 1471792 1866913 1807733 3700017 3907855 3614258 2905963 2485697 2751616 3000558 3478311 4563764 3860128 2798512 3738396 2941240 3203141 3862091 (S)-3-Hydroxyisobutyric acid_HMDB0000023 3-Hydroxyisobutyric acid 25948290 24967042 22309276 22767690 27108679 26899708 28177917 27508989 27444033 24542178 24055072 22884465 21745914 22344609 5767194 6739750 6109848 3467753 4504399 6364141 3837750 3392399 3118717 Sarcosine_HMDB0000271 Sarcosine 12532604 7977601 11462981 3386859 10494752 6618278 9291899 5276558 3337473 13758962 9485812 10122224 4711737 7958625 10497218 10049539 4496401 6386693 7190764 6204536 9041629 4925858 9992135 Sorbitol_HMDB0000247 Sorbitol 421688 424378 646942 279325 299764 621155 759687 569667 1240678 1313359 1178756 966703 801161 829710 810923 1230207 1257010 710363 906734 2114555 1147106 1068361 998216 Stearic acid_HMDB0000827 Stearic acid 11223755 11795310 10412850 16059899 13227954 16492388 18651776 17881833 20158946 17902773 18409352 16059176 16019663 18987178 13922683 16131419 16555710 14250243 16376358 18545589 17260914 19339353 15589392 Stigmasterol_HMDB0000937 Stigmasterol 589427 1921701 1083909 2177164 549104 1175720 1131596 616144 1038018 12664 549451 637725 2206803 3454348 1610163 132481 382292 1920863 1016121 24863 2922437 1705373 222405 Succinic acid_HMDB0000254 Succinic acid 407738 659906 445604 762192 444766 553160 597448 846214 936240 1164323 1001690 797239 712776 798632 692952 620968 1347749 775953 1516838 1183097 549357 739105 467053 Sucrose_HMDB0000258 Sucrose 574674 173694 178143 198038 259426 273393 316704 246445 220248 827129 755471 567160 442533 948499 453723 224646 485640 445104 254539 329234 224503 352527 322284 Taurine_HMDB0000251 Taurine 9389674 21960498 15856495 23637812 16284883 23542927 21827377 20849604 16186697 20884052 20489244 19209904 17426674 17605512 10281342 12534222 27633312 21284946 12748681 11559634 11178714 22097253 5576346 Threonic acid_HMDB0000943 Threonic acid 4492085 5625860 6316546 3841147 5061888 4318578 5076154 4773204 7584000 8603593 7510811 6476770 5328107 5728262 5892158 6401589 12939170 8229323 3350227 4915689 4169834 5733929 7481173 Thymidine_HMDB0000273 Thymidine 51906 79521 101302 112588 99094 29685 27516 47151 37596 49712 83001 62321 51764 73316 68287 107170 65596 109081 40333 31355 25469 49673 74371 Thymine_HMDB0000262 Thymine 119070 190261 180671 175110 167699 53465 55654 75844 42589 264354 131404 104699 100391 94809 115440 183540 152599 145053 64668 86562 40055 63392 141148 Triethanolamine_HMDB0032538 Triethanolamine 92859 81002 59804 76335 86455 114273 180983 138940 133526 162247 140666 119765 107838 113437 97617 109069 141883 174393 106041 94081 109314 125743 98136 Tyramine_HMDB0000306 Tyramine 3089779 7496377 5622913 10201413 13169486 7464496 6475893 5011268 9010767 6685455 5719397 4627124 3818396 3918465 5587166 6280106 7201923 4619653 2698633 2692179 1513642 3143357 3292435 Uracil_HMDB0000300 Uracil 219434 477834 302082 315363 242887 210911 163417 249288 241587 509603 382183 274901 286846 287560 216858 288496 1438306 323538 212948 208017 114094 183673 198270 Urea_HMDB0000294 Urea 50595791 50553545 51676564 54698970 55409631 52865507 56380027 58065322 62198406 57692968 54822678 52008047 50891480 51792241 51361397 50932377 51998954 46971330 48247976 54095567 48272017 49277622 50443274 Uridine_HMDB0000296 Uridine 199400 361836 329136 528122 252913 303928 280382 269779 396296 476559 421813 280543 308012 401156 348864 403836 558894 460658 356826 461428 365471 737902 312737 Xanthine_HMDB0000292 Xanthine 2824 1708 2432 226435 1129470 958924 1339405 2049120 539711 545310 613797 396893 320230 364393 2920 3523 4686 288036 121643 2498 20802 534634 18759