Metabolite_name RefMet_name KO-1 KO-2 KO-3 WT-1 WT-2 WT-3 Factors - Genotype:circLARP2-deficiency Genotype:circLARP2-deficiency Genotype:circLARP2-deficiency Genotype:Wild-type Genotype:Wild-type Genotype:Wild-type Arachidic acid m+0 Arachidic acid 65.8199 62.0970 66.5744 43.3174 46.3954 46.0486 Arachidic acid m+10 Arachidic acid 1.7447 2.9545 3.3207 3.3810 4.0294 3.5015 Arachidic acid m+12 Arachidic acid 5.9175 6.3429 5.8194 6.9783 6.4080 6.5889 Arachidic acid m+14 Arachidic acid 4.5316 3.8269 2.7695 8.1654 8.1786 8.3091 Arachidic acid m+16 Arachidic acid 2.9699 2.8846 3.2421 7.5937 6.7301 6.3663 Arachidic acid m+18 Arachidic acid 0.8834 1.2147 0.7688 4.0821 3.6477 3.7712 Arachidic acid m+2 Arachidic acid 11.4655 13.0192 12.9955 15.9532 13.9158 14.7085 Arachidic acid m+20 Arachidic acid 0.2139 0.7003 0.5431 Arachidic acid m+4 Arachidic acid 4.2366 4.3463 2.2295 6.8302 6.6682 6.4753 Arachidic acid m+6 Arachidic acid 0.2557 0.3079 0.0736 0.2354 0.2260 Arachidic acid m+8 Arachidic acid 1.1776 2.0451 1.0580 0.5822 1.2343 1.5511 Behenic acid m+0 Behenic acid 72.7991 70.9511 72.5679 56.0235 57.8558 64.8660 Behenic acid m+10 Behenic acid 1.8372 2.1694 2.1757 1.5921 1.6857 1.2580 Behenic acid m+12 Behenic acid 2.8366 3.2413 2.9141 3.1265 2.9179 2.6569 Behenic acid m+14 Behenic acid 3.2540 3.5469 3.0627 4.7083 4.6664 4.1219 Behenic acid m+16 Behenic acid 2.3481 2.9471 2.4461 5.3185 4.9781 4.0990 Behenic acid m+18 Behenic acid 1.3168 1.5926 1.2342 3.8497 3.4414 3.1029 Behenic acid m+2 Behenic acid 6.0757 5.8685 5.4711 7.5152 7.3754 6.2757 Behenic acid m+20 Behenic acid 0.3991 0.4002 0.4642 1.7919 1.7086 1.5443 Behenic acid m+4 Behenic acid 5.5407 5.7415 5.5032 9.0081 8.5990 6.8428 Behenic acid m+6 Behenic acid 1.7979 1.6870 1.8192 3.1103 3.1250 2.5733 Behenic acid m+8 Behenic acid 0.9956 1.1486 1.0380 0.6050 0.6621 0.4115 Docosadienoic acid m+0 Docosadienoic acid 50.3717 51.3162 49.1392 38.8793 37.1196 43.5271 Docosadienoic acid m+10 Docosadienoic acid 0 0 Docosadienoic acid m+12 Docosadienoic acid 1.7091 0.8399 0.9313 1.3221 0.9308 Docosadienoic acid m+14 Docosadienoic acid 3.4237 1.6143 2.9345 Docosadienoic acid m+16 Docosadienoic acid 1.6043 2.1450 2.5687 Docosadienoic acid m+2 Docosadienoic acid 32.0852 32.1900 38.4310 30.8112 30.3589 29.3413 Docosadienoic acid m+4 Docosadienoic acid 15.8335 15.6536 12.4298 22.5744 26.1681 18.8874 Docosadienoic acid m+6 Docosadienoic acid 1.7219 1.2717 1.8100 Docosapentaenoic acid m+0 Docosapentaenoic acid 95.9877 96.4198 95.7934 92.8152 92.9969 92.8188 Docosapentaenoic acid m+2 Docosapentaenoic acid 4.0123 3.5802 4.2066 7.1724 7.0031 7.0893 Docosapentaenoic acid m+4 Docosapentaenoic acid 0.0124 0.0919 Docosatetraenoic acid m+0 Docosatetraenoic acid 89.4519 87.9756 89.5904 84.7439 85.6711 86.2535 Docosatetraenoic acid m+2 Docosatetraenoic acid 10.5481 12.0244 10.4096 14.0600 14.3289 13.7072 Docosatetraenoic acid m+4 Docosatetraenoic acid 0.0393 Eicosadienoic acid Eicosadienoic acid 71.4436 87.2583 71.4605 54.4599 60.1163 62.2680 Eicosadienoic acid m+2 Eicosadienoic acid 28.5564 12.7417 27.7665 39.8768 37.7386 34.0270 Eicosadienoic acid m+4 Eicosadienoic acid 3.1803 2.1451 3.7050 Eicosatrienoic acid m+0 Eicosatrienoic acid 96.0282 96.9076 98.9448 91.4184 92.5887 92.5911 Eicosatrienoic acid m+2 Eicosatrienoic acid 3.9718 3.0924 1.0552 7.5379 7.4113 6.1461 Eicosatrienoic acid m+4 Eicosatrienoic acid 0.5648 0.8252 Elaidic acid m+0 Elaidic acid 47.6735 77.5919 65.1585 29.9935 47.5856 39.4325 Elaidic acid m+10 Elaidic acid 6.2720 6.2173 6.9950 8.3009 6.7820 6.0331 Elaidic acid m+12 Elaidic acid 7.8263 4.6426 9.6330 9.8475 10.8726 10.9179 Elaidic acid m+14 Elaidic acid 6.0465 3.7098 2.2896 13.1404 8.5400 9.9087 Elaidic acid m+16 Elaidic acid 1.5618 0.2796 0.8469 7.0270 4.9242 6.4620 Elaidic acid m+18 Elaidic acid 0.9703 0.8393 0.8477 Elaidic acid m+2 Elaidic acid 7.5271 6.2594 14.3848 10.4586 12.4314 Erucic acid m+0 cis-Erucic acid 65.5746 65.2230 62.8606 60.8227 52.8513 63.3623 Erucic acid m+10 cis-Erucic acid 0.6315 0.6280 0.6920 0.3922 0.5672 0.5038 Erucic acid m+12 cis-Erucic acid 1.8811 2.4804 2.2788 1.3917 0.8220 0.9343 Erucic acid m+14 cis-Erucic acid 1.4509 1.0026 1.5415 1.4475 2.1346 0.8910 Erucic acid m+16 cis-Erucic acid 1.0421 0.5290 0.3044 1.1241 1.2841 0.8339 Erucic acid m+18 cis-Erucic acid 0.8627 Erucic acid m+2 cis-Erucic acid 15.7412 16.1679 16.8722 15.2625 20.1915 15.3309 Erucic acid m+20 cis-Erucic acid 0.1124 Erucic acid m+4 cis-Erucic acid 13.1158 13.5762 14.6922 16.2606 19.8858 15.7771 Erucic acid m+6 cis-Erucic acid 0.5629 0.3929 0.7583 3.1736 2.1785 1.3729 Gadoleic acid m+0 cis-Gadoleic acid 48.7170 55.8980 45.1380 37.8368 38.0743 40.0472 Gadoleic acid m+10 cis-Gadoleic acid 0.7519 0.7869 1.6034 1.1660 0.8067 0.8674 Gadoleic acid m+12 cis-Gadoleic acid 3.0733 3.2521 3.3900 3.5016 2.9673 3.1211 Gadoleic acid m+14 cis-Gadoleic acid 2.5287 2.2990 2.8314 4.3722 4.1261 3.7563 Gadoleic acid m+16 cis-Gadoleic acid 0.5682 1.0135 1.6278 3.3396 2.7269 3.2553 Gadoleic acid m+18 cis-Gadoleic acid 0.1079 0.4008 0.6410 1.8214 1.9058 1.4514 Gadoleic acid m+2 cis-Gadoleic acid 0.1390 0.2527 0.2563 0.7172 0.0497 0.1806 Gadoleic acid m+20 cis-Gadoleic acid 0.1171 0.1741 0.2440 Gadoleic acid m+8 cis-Gadoleic acid 0.0941 0.0744 0.0967 0.0366 Hexadecenoic acid Hexadecenoic acid 88.1443 87.0269 88.1733 75.9693 81.5469 78.1907 Hexadecenoic acid m+10 Hexadecenoic acid 3.4771 3.5374 2.4253 6.5009 3.2678 6.4559 Hexadecenoic acid m+12 Hexadecenoic acid 2.2124 3.1204 2.7196 7.5002 4.9381 6.4292 Hexadecenoic acid m+14 Hexadecenoic acid 2.1235 1.0922 2.0430 4.1131 4.7119 3.4006 Hexadecenoic acid m+16 Hexadecenoic acid 0.7182 0.5108 0.6723 Hexadecenoic acid m+6 Hexadecenoic acid 1.0522 0.7832 1.2120 1.5617 0.8010 0.6728 Hexadecenoic acid m+8 Hexadecenoic acid 2.9899 4.2129 3.4259 3.0378 4.2229 3.4815 Lignoceric acid m+0 Lignoceric acid 56.0714 54.7364 56.5335 47.1869 42.8841 53.1485 Lignoceric acid m+10 Lignoceric acid 1.8535 1.9834 1.9400 1.1042 1.2325 0.8864 Lignoceric acid m+12 Lignoceric acid 3.1120 3.3015 3.0641 2.1459 2.4776 2.0353 Lignoceric acid m+14 Lignoceric acid 4.2866 4.3071 3.9791 3.8219 4.0577 3.3120 Lignoceric acid m+15 Lignoceric acid 0.6182 0.6980 0.6955 0.7980 0.9275 0.8184 Lignoceric acid m+16 Lignoceric acid 4.1002 4.0834 4.0210 5.1115 5.3970 4.5453 Lignoceric acid m+18 Lignoceric acid 3.0053 2.9503 2.9185 4.8138 5.2636 4.3938 Lignoceric acid m+2 Lignoceric acid 7.5486 7.7162 7.2017 7.4392 8.0864 6.7117 Lignoceric acid m+20 Lignoceric acid 1.3875 1.6318 1.5791 3.4197 3.6751 2.9042 Lignoceric acid m+22 Lignoceric acid 0.3657 0.3439 0.4579 1.5449 1.5115 1.2332 Lignoceric acid m+4 Lignoceric acid 7.8304 7.8380 7.5953 8.5802 8.9215 7.5846 Lignoceric acid m+6 Lignoceric acid 5.5297 5.4533 5.2827 7.5255 8.0824 6.5205 Lignoceric acid m+8 Lignoceric acid 2.1034 2.0787 2.1338 2.5903 2.9522 2.3913 Myristic acid m+0 Myristic acid 58.1334 84.0504 80.0151 56.6436 61.5555 60.9646 Myristic acid m+10 Myristic acid 22.4325 19.9838 18.5302 17.4540 17.0129 Myristic acid m+12 Myristic acid 8.2633 10.6253 13.7874 Myristic acid m+14 Myristic acid 7.2644 Myristic acid m+6 Myristic acid 8.6938 4.5483 3.9026 5.9551 Myristic acid m+8 Myristic acid 10.7370 11.3996 9.2969 6.4611 2.2777 Nervonic acid m+0 Nervonic acid 56.5531 56.2379 58.1945 47.6533 48.8495 48.7953 Nervonic acid m+10 Nervonic acid 0.8610 0.8149 0.6641 0.5883 0.4985 0.4288 Nervonic acid m+12 Nervonic acid 1.1598 1.5964 1.2080 1.0798 0.9908 1.1732 Nervonic acid m+14 Nervonic acid 1.7365 1.8387 1.7834 1.9122 1.6999 1.6363 Nervonic acid m+16 Nervonic acid 1.7184 1.7930 1.7997 2.3762 2.0581 2.1264 Nervonic acid m+18 Nervonic acid 1.1692 1.2862 1.1736 2.1285 2.0240 2.0064 Nervonic acid m+2 Nervonic acid 11.9589 11.3264 10.9085 10.7165 10.5521 10.8899 Nervonic acid m+20 Nervonic acid 0.5800 0.5328 0.5893 1.3967 1.3210 1.2842 Nervonic acid m+22 Nervonic acid 0.1111 0.1042 0.0692 0.5475 0.5818 0.5593 Nervonic acid m+4 Nervonic acid 13.9998 14.2589 13.3925 16.0741 15.7829 15.6569 Nervonic acid m+6 Nervonic acid 7.7044 7.9750 7.7208 11.3580 11.2636 11.0592 Nervonic acid m+8 Nervonic acid 1.3689 1.2267 1.1477 1.7476 1.7256 1.8142 Oleic acid m+0 Oleic acid 82.0465 81.6604 81.3792 73.7074 75.3170 77.0943 Oleic acid m+10 Oleic acid 2.6794 3.0485 3.0223 3.1051 2.7757 2.6187 Oleic acid m+12 Oleic acid 2.8552 3.0510 3.0023 4.1761 3.9399 3.5684 Oleic acid m+14 Oleic acid 2.0217 2.0133 2.0815 3.8133 3.6346 3.2222 Oleic acid m+16 Oleic acid 0.8564 0.7887 0.8506 2.1195 2.0013 1.8493 Oleic acid m+18 Oleic acid 0.1232 0.0681 0.0719 0.4605 0.5221 0.4403 Oleic acid m+2 Oleic acid 4.7757 4.8925 5.2923 7.6498 7.4672 6.7156 Oleic acid m+4 Oleic acid 0.3440 0.3583 0.3561 0.3498 0.2312 0.3462 Oleic acid m+6 Oleic acid 0.8973 0.9824 0.9797 0.7524 0.6388 0.6900 Oleic acid m+8 Oleic acid 1.8849 1.9931 2.0122 1.7403 1.5739 1.4408 Palmitic acid m+0 Palmitic acid 70.9766 63.9859 67.6461 58.5571 66.8111 59.1641 Palmitic acid m+10 Palmitic acid 7.6744 9.2083 8.3894 9.1134 7.8796 8.6670 Palmitic acid m+12 Palmitic acid 6.3616 7.3204 7.4249 10.5004 8.0840 10.3177 Palmitic acid m+14 Palmitic acid 2.9286 3.4646 3.0830 6.9670 5.5124 6.5833 Palmitic acid m+16 Palmitic acid 0.5471 0.6447 0.3886 1.8949 1.5959 2.0379 Palmitic acid m+2 Palmitic acid 0.0823 0.3836 0.1340 0.2869 0.1496 0.3804 Palmitic acid m+4 Palmitic acid 0.7638 1.3523 1.0300 0.8306 0.5410 0.7371 Palmitic acid m+6 Palmitic acid 3.1021 3.9155 3.0621 2.5246 1.9796 2.2787 Palmitic acid m+8 Palmitic acid 6.0987 7.3789 6.4637 5.5716 4.3848 5.5003 Stearic acid m+0 Stearic acid 86.4611 82.2308 87.2806 72.5323 82.5727 71.4936 Stearic acid m+10 Stearic acid 2.4761 3.1931 2.1780 3.7191 2.2027 3.6891 Stearic acid m+12 Stearic acid 2.5763 3.2848 2.5746 4.9596 3.2830 5.2380 Stearic acid m+14 Stearic acid 1.8674 2.3766 1.6905 4.6793 3.0563 4.8711 Stearic acid m+16 Stearic acid 0.6335 0.9435 0.6694 2.7575 1.6659 2.7230 Stearic acid m+18 Stearic acid 0.0795 0.0614 0.1033 0.7050 0.4507 0.6710 Stearic acid m+2 Stearic acid 2.4265 3.4213 2.2837 5.2366 3.4549 5.5287 Stearic acid m+4 Stearic acid 0.1883 0.3881 0.1883 0.3378 0.0591 0.3061 Stearic acid m+6 Stearic acid 0.7118 0.9308 0.7484 0.8199 0.4515 0.7626 Stearic acid m+8 Stearic acid 1.6159 2.2305 1.3734 1.7984 1.1808 1.9393 Tricosanoic acid m+0 Tricosylic acid 98.6126 99.4333 100 99.7381 100 100 Tricosanoic acid m+2 Tricosylic acid 1.3874 0.5667 0.2619