Metabolite_name RefMet_name AF20_BC_196 AF20_BC_197 AF20_BC_198 AF20_BC_205 AF20_BC_191 AF20_BC_192 AF20_BC_194 AF20_BC_195 AF19_BC_217 AF19_BC_218 AF19_BC_219 AF20_BC_209 AF19_BC_214 AF19_BC_215 AF19_BC_216 AF20_BC_206 Factors - Organ:Cecum | Treatment:Germfree | Diet:Fiber-free Organ:Cecum | Treatment:Germfree | Diet:Fiber-free Organ:Cecum | Treatment:Germfree | Diet:Fiber-free Organ:Cecum | Treatment:Germfree | Diet:Fiber-free Organ:Cecum | Treatment:Germfree | Diet:Fiber-rich Organ:Cecum | Treatment:Germfree | Diet:Fiber-rich Organ:Cecum | Treatment:Germfree | Diet:Fiber-rich Organ:Cecum | Treatment:Germfree | Diet:Fiber-rich Organ:Cecum | Treatment:Gnotobiote (14SM) | Diet:Fiber-free Organ:Cecum | Treatment:Gnotobiote (14SM) | Diet:Fiber-free Organ:Cecum | Treatment:Gnotobiote (14SM) | Diet:Fiber-free Organ:Cecum | Treatment:Gnotobiote (14SM) | Diet:Fiber-free Organ:Cecum | Treatment:Gnotobiote (14SM) | Diet:Fiber-rich Organ:Cecum | Treatment:Gnotobiote (14SM) | Diet:Fiber-rich Organ:Cecum | Treatment:Gnotobiote (14SM) | Diet:Fiber-rich Organ:Cecum | Treatment:Gnotobiote (14SM) | Diet:Fiber-rich 10-Hydroxydecanoate 10-Hydroxydecanoic acid 1-Aminoethylphosphonate 2^_3^-cCMP 2',3' cyclic CMP 2_3-DPG 2,3-Diphosphoglyceric acid 2_3-Pyridinedicarboxylate Quinolinic acid 26 15 17 11 40 15 17 13 20 36 15 15 8.9000 13 10 19 2_4-Dihydroxypyrimidine-5-carboxylate Uracil-5-carboxylic acid 2_5-Dihydroxybenzoate Gentisic acid 34 48 37 2-Amino-3-phosphonopropionate 2-Aminoethylphosphonate Ciliatine 2-Deoxyglucose 6-phosphate 2-Deoxy-D-glucose 6-phosphate 64 51 44 128 2-Deoxyribose 1-phosphate Deoxyribose 1-phosphate 2-Furoate 2-Furoic acid 2-Hydroxy-4-methylpentanoate D-Leucic acid 55 57 49 50 44 30 16 36 2-Hydroxybutyrate 2-Hydroxybutyric acid 23 23 25 19 31 35 27 26 41 62 50 54 2-Hydroxyglutarate 2-Hydroxyglutaric acid 6.4000 14 9.8000 12 13 15 25 32 28 36 108 165 69 71 2-Hydroxyisobutyrate 2-Hydroxyisobutyric acid 23 22 23 2-Hydroxyoctanoate 2-Hydroxyoctanoic acid 2-Hydroxypentanoate 2-Hydroxyvaleric acid 80 110 95 52 192 228 188 383 2-Hydroxyphenylacetate 2-Hydroxyphenylacetic acid 2-Isopropylmalate 2-Isopropylmalic acid 4.1000 1.5000 3.1000 4.5000 114 186 111 120 2-Oxoadipate Oxoadipic acid 2-Oxobutyrate 3-Methyl pyruvic acid 2-Oxoglutarate 2-Oxoglutaric acid 2-Oxoisopentanoate Ketoisovaleric acid 15 16 2-Oxooctanoate 2PG 2-Phosphoglyceric acid 2-Quinolinecarboxylate Quinaldic acid 2-Thiopheneacetate 2-Thienylacetic acid 3-(2-Hydroxyphenyl)propionate 3-(2-Hydroxyphenyl)propanoic acid 3-(4-Hydroxyphenyl)propionate Desaminotyrosine 3^_5^-Cyclic dAMP 3^-AMP 3'-AMP 3-Hydroxy-3-methylglutarate 3-Hydroxymethylglutaric acid 846 1201 743 537 3-Hydroxybutyrate 3-Hydroxybutyric acid 284 591 536 403 76 83 138 88 1705 1394 1271 1051 371 502 384 1691 3-Hydroxypropionate Hydroxypropionic acid 3-Indolebutyrate 3-Indolebutyric acid 3-Indoxyl sulfate Indoxyl sulfate 8.8000 35 5.3000 3-Methylbutanoate Isovaleric acid 27 34 29 34 573 771 519 658 3PG 3-Phosphoglyceric acid 3-Phenyllactate Phenyllactic acid 3-Phenylpropionate Hydrocinnamic acid 3-Ureidopropionate Ureidopropionic acid 4-Acetylbutyrate 5-Ketocaproic acid 13 15 16 10 18 16 15 16 12 14 15 16 15 9.5000 4-Hydroxy-3-methoxymandelate Vanillylmandelic acid 4-Hydroxymandelate 4-Hydroxymandelic acid 92 103 67 4-Methyl-2-oxopentanoate Ketoleucine 13 16 23 18 12 18 20 55 33 23 26 4-Methylthio-2-oxobutyrate 2-Oxo-4-methylthiobutanoic acid 4-Oxohexanoate 4-Oxopentanoate Levulinic acid 4-Pyridoxate 4-Pyridoxic acid 5.8000 5.1000 4.2000 3.2000 8.9000 6.5000 8.3000 2.8000 7 11 5.8000 3.7000 24 29 23 16 6-Hydroxyhexanoate 6-Hydroxycaproic acid 6-Phosphogluconate 6-Phosphogluconic acid Acetyl CoA Acetyl-CoA 1.8000 Adenosine 3^_5^-diphosphate Adenosine 3',5'-diphosphate Adenosine 5^-phosphosulfate Adenosine phosphosulfate Adenylosuccinate Adenylsuccinic acid Adipate Adipic acid 37 36 31 27 ADP ADP 3.8000 4.3000 8.4000 6.3000 22 ADP-glucose ADP-glucose ADP-ribose ADP-ribose 12 16 23 22 26 39 Allantoate Allantoic acid 61 69 47 47 225 164 132 152 35 65 70 126 73 111 189 AMP AMP 3.6000 3.6000 11 3.5000 37 24 13 17 9.4000 39 61 49 49 184 ATP ATP Azelate Azelaic acid 39 37 29 26 45 49 43 16 33 32 35 33 52 55 41 35 Barbiturate Barbituric acid 44 Benzoate Benzoic acid Benzoylformate Phenylglyoxylic acid Benzylsuccinate (R)-2-Benzylsuccinic acid Biotin Biotin Butyrate Butyric acid 78 41 2087 3151 2268 2580 679 836 645 11096 cAMP 3',5' cyclic AMP 9.4000 14 Carbamoylaspartate Carbamoylaspartate 20 21 13 23 50 57 27 45 Carbamoylphosphate Carbamoylphosphate CDP CDP CDP-choline CDP-choline cGMP 3',5' cyclic GMP Cholate Cholic acid 10 30 cIMP cis-Aconitate cis-Aconitic acid 2.5000 9.8000 12 6.4000 4.6000 12 5 7.9000 Citraconate Citraconic acid 45 26 18 11 15 11 13 4.6000 7.5000 19 9.9000 7.5000 32 45 27 41 Citramalate Citramalic acid 244 375 198 151 Citrate Citric acid 45 9 11 18 187 286 143 208 124 6.3000 102 23 261 139 109 508 CMP CMP 3.8000 3 6.5000 46 53 30 32 11 13 10 25 CMP-N-acetylneuraminate CMP-N-acetylneuraminic acid 20 11 5.9000 10 6.2000 11 6.6000 12 9.8000 14 CoA Coenzyme A Crotonate Crotonic acid CTP CTP Cysteate Cysteic acid 7.4000 20 26 23 16 Cysteine S-sulfate Cysteine-S-sulfate 1312 1779 1737 1933 299 360 327 188 71 96 71 106 5.1000 9.3000 Cysteine sulfinate 3-Sulfino-alanine 47 52 29 56 36 39 dADP dADP dAMP dAMP dATP dATP DCA Deoxycholic acid dCDP dCDP dCMP dCMP dCTP dCTP Deamido-NAD+ Nicotinic acid adenine dinucleotide 72 87 51 17 Decanoate Capric acid 29 33 36 25 27 28 40 19 91 343 59 46 31 22 15 dGTP dGTP DHAP Dihydroxyacetone phosphate Digalacturonate Digalacturonic acid 13 8.4000 Dihydroorotate 4,5-Dihydroorotic acid dITP dITP Dodecanedioate Dodecanedioic acid 1.1000 1 1.2000 1.3000 0.8900 0.7600 1.6000 1.2000 1 1.6000 1.3000 0.8200 1.3000 0.7600 Dodecanoate Lauric acid 41 37 66 39 31 34 24 96 283 70 50 22 dTDP dTDP 8.5000 dTMP dTMP 16 16 18 10 16 dTTP dTTP dUDP dUDP dUMP dUMP dUTP dUTP F1_6P Fructose 1,6-bisphosphate F6P Fructose 6-phosphate 41 47 31 43 FAD FAD 14 9 14 20 21 19 37 Folate Folic acid Fumarate Fumaric acid 30 29 11 15 20 33 13 98 102 56 105 67 100 61 63 G1P Glucose 1-phosphate 25 30 22 67 G3P Glyceraldehyde 3-phosphate G6P Glucose 6-phosphate 7.7000 7.7000 6.8000 42 247 244 132 305 Galacturonate 1-phosphate GDP GDP GDP-mannose GDP-mannose Gluconate Gluconic acid 3485 2804 2615 2379 20121 16456 17658 9448 880 1759 796 663 1597 1848 1195 1460 Glucosamine 6-phosphate Glucosamine 6-phosphate Glucuronate Glucuronic acid 8917 9082 7332 8738 2410 1834 1668 1593 139 240 122 204 98 116 56 93 Glutarate Glutaric acid 21 19 22 29 30 26 28 365 399 292 204 Glycerate Glyceric acid 290 315 429 230 323 291 303 347 374 365 421 249 280 209 320 Glycerophosphate sn-Glycero-3-phosphate 9.2000 6.6000 10 10 26 9.6000 30 53 43 41 121 Glycocholate Glycocholic acid Glycolate Glycolic acid 187 263 351 220 282 345 330 505 709 486 573 306 370 289 389 Glyoxylate Glyoxylic acid GMP GMP 5.8000 5.4000 6.6000 4.4000 4.9000 20 GTP GTP Heptanoate Heptylic acid 13 11 Hexanoate Caproic acid 15 16 15 13 16 9.1000 23 22 17 24 14 15 Hippurate Hippuric acid Homovanillate Homovanillic acid IDP IDP IMP IMP 7.8000 18 14 Indolelactate Indolelactic acid 19 18 14 15 18 22 18 13 17 20 17 18 49 89 53 578 Isethionate 2-Hydroxyethanesulfonate 348 229 181 219 309 195 154 77 10 6.7000 7 9.9000 13 Isobutyryl CoA Isobutyryl-CoA 3.5000 Isocitrate Isocitric acid 4.4000 15 22 12 8.6000 5.9000 Itaconate Itaconic acid ITP ITP Lactate Lactic acid 2571 1414 2852 1395 1014 1027 2634 1602 1563 1013 871 1236 773 2776 1871 3453 Malate Malic acid 94 27 117 28 107 101 198 110 631 409 326 741 1402 1460 1126 1024 Malonate Malonic acid 38 32 41 20 194 215 241 96 110 153 92 169 589 809 553 474 Malonyl CoA Malonyl-CoA Methanesulfonate Methanesulfonic acid Methyl sulfate Methyl sulfate 30 32 21 27 18 18 12 35 28 86 91 40 40 36 26 (Methylthio)acetate (Methylthio)acetic acid m-Hydroxybenzoate 3-Hydroxybenzoic acid Mucate Galactaric acid 14 13 28 14 152 187 202 46 6.8000 15 7.6000 21 N-Acetylaspartate N-Acetylaspartic acid 7.3000 272 490 367 271 80 99 77 105 N-Acetyl-beta-alanine N-Acetyl-beta-alanine N-Acetylglucosamine 1-phosphate N-Acetyl-D-glucosamine 1-phosphate 6.1000 9.1000 11 14 6.2000 18 30 21 79 26 22 20 55 N-Acetylglucosamine 6-phosphate N-Acetyl-glucosamine 6-phosphate 4.9000 44 30 25 91 N-Acetylglutamate N-Acetylglutamic acid 5.1000 3.7000 3.1000 12 8.4000 6.9000 6.4000 56 75 68 91 89 138 90 442 N-Acetylleucine N-Acetylleucine 11 9.6000 9.3000 9.7000 11 10 9.5000 7.6000 35 32 32 28 33 32 31 31 N-Acetylmethionine N-Acetylmethionine 32 42 37 36 31 34 32 17 50 47 51 58 11 23 15 19 N-Acetylmuramate N-Acetylmuramic acid N-Acetylneuraminate N-Acetylneuraminic acid 1711 1392 1227 1759 244 177 183 145 59 55 57 61 38 49 32 30 N-Acetylphenylalanine N-Acetylphenylalanine 14 15 13 12 21 21 19 11 NAD+ NAD 558 566 581 622 NADH NADH NADP+ NADP 7.7000 NADPH NADPH N-Carbamylglutamate Carglumic acid N-Formylaspartate N-Formyl-aspartic acid 9.4000 12 12 11 N-Formylmethionine N-Formylmethionine 12 11 8.9000 9.2000 11 9.3000 7.3000 6 38 43 39 34 62 41 39 35 Nicotinate Nicotinic acid 174 193 139 111 549 472 469 547 o-Coumarate trans-o-Coumaric acid Octanoate Caprylic acid 10 12 7.8000 9.3000 13 27 15 18 8.2000 o-Hydroxybenzoate Salicylic acid o-Hydroxyhippurate Salicyluric acid O-Phosphoserine Phosphoserine 13 Orotate Orotic acid 68 86 54 132 Orotidine 5^-monophosphate Orotidylic acid P1_ P4-Di(adenosine-5^) tetraphosphate Pantothenate Pantothenic acid 9.4000 9.5000 15 8.7000 7.2000 6.5000 6.2000 5.8000 36 28 30 37 27 30 29 22 p-Coumarate cis-p-Coumaric acid 43 27 26 Pelargonate Pelargonic acid 21 31 25 18 25 19 15 34 47 24 42 15 15 Pentanoate Valeric acid PEP Phosphoenolpyruvic acid Phenaceturate Phenylacetylglycine Phenyl phosphate Phenyl phosphate Phenylpyruvate Phenylpyruvic acid Phosphonoacetate Phosphonoacetate Phthalate Phthalic acid 3.7000 2.7000 2.3000 2.6000 6.2000 5.9000 5 3.1000 3.8000 4.8000 3.3000 3.6000 5.2000 6.4000 4.9000 3.4000 p-Hydroxybenzoate 4-Hydroxybenzoic acid 97 109 84 79 p-Hydroxyphenylacetate 4-Hydroxyphenylacetic acid 2040 2323 2116 2985 Pimelate Pimelic acid 5.4000 5.3000 5.4000 3.8000 22 28 19 14 Porphobilinogen Porphobilinogen Propionate Propionic acid 238 222 164 247 10023 16084 11062 10898 10329 12590 11955 4987 Prostaglandin E2 PGE2 685 1022 688 835 7648 7321 9915 1678 1185 1427 1294 Prostaglandin F2alpha PGF2alpha PRPP Phosphoribosyl pyrophosphate Pyrrole-2-carboxylate Pyrrole-2-carboxylic acid Pyruvate Pyruvic acid 215 Quinate Quinic acid 379 286 144 164 463 427 365 317 41 51 56 52 R5P Ribose 5-phosphate 22 Ribulose 1_5-diphosphate Ribulose 1,5-bisphosphate Ru5P Ribulose 5-phosphate 10 20 19 19 15 25 S7P Sedoheptulose 7-phosphate 53 43 27 75 Saccharate Glucaric acid 265 374 379 91 Sebacate Sebacic acid 2.6000 4.1000 4.3000 3.2000 1.8000 1.9000 1.7000 3.7000 2.7000 2.7000 2.7000 2 Serine O-sulfate Serine-O-sulfate Shikimate Shikimic acid Sinapate Sinapic acid 235 261 283 328 Sorbitol 6-phosphate Pseudouridine Succinate Succinic acid 213 80 163 86 107 95 155 107 17380 13155 18849 40141 164298 197902 160743 103702 Succinyl CoA Succinyl-CoA Syringate Syringic acid Tartrate Tartaric acid 8.6000 10 13 7.2000 50 58 47 15 Taurocholate Taurocholic acid 890 1063 3034 1865 203 213 1243 250 957 409 1091 2233 186 260 171 373 TDP-glucose dTDP-glucose Terephthalate Terephthalic acid 17 19 19 16 18 16 20 16 9.3000 14 8.6000 12 11 16 14 13 threo-beta-methylaspartate 612 832 681 519 408 411 Threonate Threonic acid 649 551 512 524 369 322 275 197 568 701 534 509 624 702 565 588 Tiglate Tiglic acid trans-4-Hydroxy-3-methoxycinnamate trans-Ferulic acid trans-Aconitate trans-Aconitic acid trans-Cinnamate trans-Cinnamic acid Trehalose 6-phosphate Trehalose 6-phosphate UDP UDP 9.5000 12 UDP-glucose UDP-glucose 8.4000 6.4000 41 64 45 48 UDP-glucuronate UDP-glucuronic acid 8.4000 12 7.4000 10 UDP-N-acetylglucosamine UDP-N-acetylglucosamine 15 4.6000 6.8000 28 42 30 79 UMP UMP 8.5000 6.3000 13 23 14 37 48 29 78 46 45 35 99 Undecanoate Undecylic acid 8.7000 21 113 15 7.9000 Urate Uric acid 134 164 169 121 205 221 252 151 55 49 37 45 73 UTP UTP Xanthurenate Xanthurenic acid 38 110 35 22 68 76 51 12 XMP XMP XTP Xanthosine 5-triphosphate