Metabolite_name RefMet_name M-1 M-3 M-4 M-5 M-6 M-7 G-1 G-2 G-4 G-5 G-6 G-7 Factors - Treatment:2 times per week with 3 weeks consecutive respectively intraperitoneal injection with 0.2ml normal saline Treatment:2 times per week with 3 weeks consecutive respectively intraperitoneal injection with 0.2ml normal saline Treatment:2 times per week with 3 weeks consecutive respectively intraperitoneal injection with 0.2ml normal saline Treatment:2 times per week with 3 weeks consecutive respectively intraperitoneal injection with 0.2ml normal saline Treatment:2 times per week with 3 weeks consecutive respectively intraperitoneal injection with 0.2ml normal saline Treatment:2 times per week with 3 weeks consecutive respectively intraperitoneal injection with 0.2ml normal saline Treatment:2 times per week with 3 weeks consecutive respectively intraperitoneal injection with 25mg/kg gemcitabine in 0.2ml Treatment:2 times per week with 3 weeks consecutive respectively intraperitoneal injection with 25mg/kg gemcitabine in 0.2ml Treatment:2 times per week with 3 weeks consecutive respectively intraperitoneal injection with 25mg/kg gemcitabine in 0.2ml Treatment:2 times per week with 3 weeks consecutive respectively intraperitoneal injection with 25mg/kg gemcitabine in 0.2ml Treatment:2 times per week with 3 weeks consecutive respectively intraperitoneal injection with 25mg/kg gemcitabine in 0.2ml Treatment:2 times per week with 3 weeks consecutive respectively intraperitoneal injection with 25mg/kg gemcitabine in 0.2ml 2^-Deoxyinosine Deoxyinosine 1706577.2010 1610218.8050 1002763.9520 910480.1672 2028078.4480 1776796.7900 1470159.8730 1489556.3100 1898027.9120 1255986.2800 1760496.3790 1285836.9130 2-hydroxy-2-phenylpropanoic acid 633396.2675 476599.9890 804634.4719 1105647.5270 470868.6053 634929.7779 709441.2235 814818.6217 655515.8340 983600.8236 564194.1110 570318.7426 3-Hydroxybenzoic acid 3-Hydroxybenzoic acid 27636.7187 27186.9696 41239.5577 47380.6674 17564.4274 32382.6118 35769.8187 29705.2921 37677.8084 37293.4425 24847.4779 29987.2769 3-Hydroxyphenylpropionic acid 3-(3-Hydroxyphenyl)propanoic acid 633396.2675 476599.9890 804634.4719 1105647.5270 470868.6053 634929.7779 709441.2235 814818.6217 655515.8340 983600.8236 564194.1110 531550.4489 4-Hydroxybenzoic acid 4-Hydroxybenzoic acid 32302.0923 34064.6071 46397.0771 49653.0570 19114.4289 33753.5897 37793.7316 34588.2702 42174.6954 48219.9026 26488.9889 34958.5417 Allantoin Allantoin 26173.4517 24442.0065 41401.2416 50587.2392 21493.2574 30947.1178 22660.2581 19177.2368 28816.0769 22901.8599 17760.7424 22996.1384 Azelaic acid Azelaic acid 928120.8750 599379.5366 897255.7432 1026170.9480 486079.9367 723083.1296 755238.8513 542680.1834 500950.0973 866609.7098 822168.9801 283769.5550 Cinnamoylglycine Cinnamoylglycine 30303.2017 27339.1550 62028.4204 38425.0335 16548.9083 26212.4606 23448.0963 39140.9551 26137.4247 42430.8544 15394.3080 57240.2625 Cis-Aconitic acid cis-Aconitic acid 406025.2483 366621.2472 390788.0905 699300.7983 381030.8480 354044.8371 491166.5654 335073.4401 623720.2539 409939.4765 409816.0160 404354.6930 Citraconic acid Citraconic acid 347822.5884 235341.5354 292062.8603 601573.0478 240792.7042 406274.0196 252203.1673 340120.3446 411193.1294 334125.1724 372738.3850 303879.6155 Citramalic acid Citramalic acid 59105.6619 59254.1270 70884.8497 75344.0118 46744.3431 47075.8993 44151.2025 41096.2008 66919.4492 80960.6900 45835.0717 69753.5154 Citrate Citric acid 45172579.9800 41062444.6600 61394756.1600 45003714.7100 35228968.8900 38090727.1600 50774017.9200 47699342.8900 59684517.0300 64543934.4200 49528116.8500 42501022.4100 D-Fructose Fructose 2445575.7120 3342083.2180 2596066.7520 1863970.7180 2895747.8370 2480991.0120 2898635.7260 2306808.2270 2842074.3830 2917088.7770 3161895.6700 2189390.1020 D-Glucose 6-phosphate Glucose 6-phosphate 876994.6114 920505.7641 587570.1181 515015.9433 1155988.6260 1364810.1880 1073200.7780 1174495.7310 1321224.1880 862294.9038 1045095.1400 1359042.9760 Docosahexaenoic acid Docosahexaenoic acid 186139.8519 167942.3595 173444.2973 185820.9929 151750.9329 176675.4474 155481.8168 159615.7004 198064.4012 148035.7328 157308.8714 181711.4826 dUMP dUMP 36602.8942 41296.2468 43677.2956 32824.3507 19377.0162 34322.4774 47211.3254 70281.9116 46626.9053 74559.4048 50399.0082 73438.8153 Flavin adenine dinucleotide FAD 2511513.2330 2331275.4240 2202276.3450 1748250.8140 2052786.9070 2066503.7480 2445232.5450 2145927.7880 2676720.1650 2380210.5190 2363701.7280 2364256.7170 Fumarate Fumaric acid 843369.8122 748994.0810 730540.7571 476044.8251 420448.1679 894694.1559 857859.8184 1162977.5780 923850.7099 1229747.0490 830777.4665 1578256.6030 Gluconic acid Gluconic acid 67730.1046 83469.8097 113102.9895 84095.1522 59598.3023 101128.6320 86274.7130 73545.1119 131775.9376 175161.0839 94043.4646 109513.6684 Glucose Glucose 3453200.2600 4056576.2070 3407530.4550 3101665.9530 4123298.1880 3841600.4660 4072175.3400 3374661.0220 4166156.0660 3757564.8230 4611976.3910 3531337.1180 Glutaric acid Glutaric acid 63142.1792 75629.6069 86429.6812 68563.9868 55387.9305 65062.2340 76791.6022 76355.6932 102432.5639 96176.6616 77918.8966 90312.6688 Indoxyl sulfate Indoxyl sulfate 216711.5429 386174.6520 912610.4466 342709.1821 199493.8030 416573.9966 1437799.5490 1040026.0350 889238.3142 970177.3990 594867.4892 954022.7126 Isocitric acid Isocitric acid 32665618.5500 38601395.8900 47171450.6300 34620235.9700 33590105.3300 38254428.2600 38649213.7700 30106026.8600 47333753.3200 46826498.8900 44592182.8900 33906813.0500 L-Lactate Lactic acid 13430319.2500 13291584.6900 12080827.0500 10593406.3100 13897443.5900 12285680.4900 12416600.8500 11639375.4200 13513366.3600 13773044.1200 13373707.4200 12831753.1100 Maleic acid Maleic acid 843369.8122 725568.8775 730540.7571 476044.8251 752089.7314 894694.1559 857859.8184 1162977.5780 923850.7099 1247035.1290 847698.8558 1578256.6030 Malic acid Malic acid 22108980.0800 19328863.0100 20726060.7200 18614506.3600 18904180.7000 20960258.5700 21685047.7100 22488028.6800 23320485.4100 23345238 21663062.8300 23191530.7400 Malonic acid Malonic acid 2990925.0770 2196115.4870 819300.9076 2989902.9140 2616162.0870 3009578.0960 554604.1869 1451534.7820 4165497.8840 2370677.7240 4642656.1330 1586875.3970 Methylmalonic acid Methylmalonic acid 10262175.0200 12304771.8700 10566728.6100 9527978.5650 15479423.8400 13072131.5500 10343217.9800 11027647.6500 16523961.6400 12976911 16094005.4200 11128933.2600 N-Acetylglutamic acid N-Acetylglutamic acid 157552.7928 103400.2267 269395.5845 62630.4393 116565.9989 104370.3221 139923.9752 147399.3324 174411.7635 341631.9781 274490.0694 132865.0132 N-Acetyl-L-tryptophan N-Acetyl-tryptophan 12637.3719 10846.5588 26151.9833 8261.9034 13328.6945 8764.7470 12343.4871 13822.3446 37318.8671 33347.7103 21339.2887 18697.5902 Oxalic acid Oxalic acid 1929631.6620 2075042.9380 1855046.8510 1663249.7430 1962335.4470 1887535.1160 1800374.4620 1774855.5700 2153950.5800 1902151.7090 2023540.4960 1979743.1430 Phenyllactic acid Phenyllactic acid 151466.7912 126050.0094 262114.0609 207357.7433 122072.9670 96149.9379 184208.9790 101854.2560 86986.2722 95715.5216 105778.6531 142711.6650 p-Hydroxyphenylpropionic acid 288898.4919 253652.8129 516426.0674 431988.7390 120742.2804 411942.7118 228315.8946 232263.0490 429908.8878 277792.6660 330104.1834 364564.8206 Sebacic acid Sebacic acid 115903.8727 75391.9655 97200.2490 143956.0855 53048.2970 82262.0219 103775.0480 86282.4149 84105.2968 115567.7102 93229.9783 118330.0225 Succinic acid Succinic acid 10293883.9600 11039360.8800 10661151.2700 9108569.8680 14007734.3000 12099899.9300 10322404.9700 11043405.7300 15637607.5100 11794805.2000 16152471.1700 9709185.8170 Taurochenodeoxycholic acid Taurochenodeoxycholic acid 5265.5246 4895.7246 11960.9557 19372.0480 1831.4219 8263.8591 8128.8208 5741.6471 8938.7331 7067.7145 26865.2729 33887.9765 Taurocholic acid Taurocholic acid 19645.4838 21730.8012 12886.6460 137518.0565 7149.5747 6667.8713 31354.1961 9342.9800 16558.1932 7254.2994 229875.2907 204648.5543 Uridine Uridine 3647511.2930 5151176.6330 2747837.1690 3137497.8620 3606412.0760 3550243.3320 3274481.5800 3029662.8330 5396667.4770 3026953.2150 3616212.6820 3887594.1130