Metabolite_name	RefMet_name	D_Serum_1	D_Serum_10	D_Serum_11	D_Serum_12	D_Serum_13	D_Serum_14	D_Serum_15	D_Serum_16	D_Serum_17	D_Serum_18	D_Serum_19	D_Serum_2	D_Serum_20	D_Serum_21	D_Serum_22	D_Serum_23	D_Serum_24	D_Serum_25	D_Serum_26	D_Serum_27	D_Serum_28	D_Serum_29	D_Serum_3	D_Serum_30	D_Serum_4	D_Serum_5	D_Serum_6	D_Serum_7	D_Serum_8	D_Serum_9	C_Serum_61	C_Serum_62	C_Serum_63	C_Serum_64	C_Serum_65	C_Serum_66	C_Serum_67	C_Serum_68	C_Serum_69	C_Serum_70	C_Serum_71	C_Serum_72	C_Serum_73	C_Serum_74	C_Serum_75	C_Serum_76	C_Serum_77	C_Serum_78	C_Serum_79	C_Serum_80	C_Serum_81	C_Serum_82	C_Serum_83	C_Serum_84	C_Serum_85	C_Serum_86	C_Serum_87	C_Serum_88	C_Serum_89	C_Serum_90	B_Serum_31	B_Serum_32	B_Serum_33	B_Serum_34	B_Serum_35	B_Serum_36	B_Serum_37	B_Serum_38	B_Serum_39	B_Serum_40	B_Serum_41	B_Serum_42	B_Serum_43	B_Serum_44	B_Serum_45	B_Serum_46	B_Serum_47	B_Serum_48	B_Serum_49	B_Serum_50	B_Serum_51	B_Serum_52	B_Serum_53	B_Serum_54	B_Serum_55	B_Serum_56	B_Serum_57	B_Serum_58	B_Serum_59	B_Serum_60
Factors	-	Factor:Control	Factor:Control	Factor:Control	Factor:Control	Factor:Control	Factor:Control	Factor:Control	Factor:Control	Factor:Control	Factor:Control	Factor:Control	Factor:Control	Factor:Control	Factor:Control	Factor:Control	Factor:Control	Factor:Control	Factor:Control	Factor:Control	Factor:Control	Factor:Control	Factor:Control	Factor:Control	Factor:Control	Factor:Control	Factor:Control	Factor:Control	Factor:Control	Factor:Control	Factor:Control	Factor:eARDS	Factor:eARDS	Factor:eARDS	Factor:eARDS	Factor:eARDS	Factor:eARDS	Factor:eARDS	Factor:eARDS	Factor:eARDS	Factor:eARDS	Factor:eARDS	Factor:eARDS	Factor:eARDS	Factor:eARDS	Factor:eARDS	Factor:eARDS	Factor:eARDS	Factor:eARDS	Factor:eARDS	Factor:eARDS	Factor:eARDS	Factor:eARDS	Factor:eARDS	Factor:eARDS	Factor:eARDS	Factor:eARDS	Factor:eARDS	Factor:eARDS	Factor:eARDS	Factor:eARDS	Factor:pARDS	Factor:pARDS	Factor:pARDS	Factor:pARDS	Factor:pARDS	Factor:pARDS	Factor:pARDS	Factor:pARDS	Factor:pARDS	Factor:pARDS	Factor:pARDS	Factor:pARDS	Factor:pARDS	Factor:pARDS	Factor:pARDS	Factor:pARDS	Factor:pARDS	Factor:pARDS	Factor:pARDS	Factor:pARDS	Factor:pARDS	Factor:pARDS	Factor:pARDS	Factor:pARDS	Factor:pARDS	Factor:pARDS	Factor:pARDS	Factor:pARDS	Factor:pARDS	Factor:pARDS
16_0_SM	SM 18:1;O2/16:0	88702.4496	58064.1099	65529.1451	62568.4909	48817.8972	47699.4279	52107.5129	48512.2777	54447.2904	48426.2631	68123.6240	73674.7518	58662.0096	73218.0047	77827.3706	47689.2088	49639.3252	43966.2594	34556.8874	62967.7511	35716.5145	52878.9954	65965.7381	71548.9916	57280.8998	49669.4685	73647.9167	62335.2273	49637.3106	46982.2917	58354.3068	33763.5287	49767.0509	44595.1809	30152.9779	54947.3485	38555.4924	27589.1099	51830.5871	40979.6401	39672.7655	22764.1408	22632.5561	48817.8972	23224.6870	24944.2563	46791.9842	59694.1857	44899.6613	35266.0175	47334.6422	49284.7586	71267.8883	53184.9913	31556.4282	41514.6499	65982.7816	30266.2671	33629.1857	20989.2504	35129.6830	49083.9737	46741.9949	34544.1883	51035.6228	48482.9546	45250.7576	25280.3977	26434.7538	29089.7727	74345.3152	31448.7262	50067.9512	28817.0337	36185.7729	44899.6613	55221.4225	56597.6574	49114.3805	44211.5439	72863.4380	21096.7132	31024.5782	40243.3101	20210.2967	36992.1043	47660.6735	39775.2093	40007.1347	37224.0297
18_0_SM	SM 18:1;O2/18:0	17175.3378	11465.7961	13081.9091	13081.9091	11810.0568	10295.9470	9750.8674	13783.6207	13416.0575	12956.6035	24351.0632	16644.1417	16448.4540	16419.4877	17600.4718	9828.8349	11219.3483	11371.7334	7195.0500	13457.4083	8047.7967	13017.7108	12748.7043	16921.6917	14342.2924	13102.8350	12272.2588	11465.7961	12389.1374	11115.1601	9118.8649	7684.6357	11774.8450	9472.9956	2965.8444	6720.5227	7433.4825	3962.1864	7702.3034	7445.1703	8781.8371	5953.4799	3791.3311	6722.6477	3688.3716	4511.8385	11762.0230	11578.2414	8426.3868	4824.2672	6476.3641	5314.4282	14628.9636	9124.0541	6228.7384	5849.3092	5982.5508	3917.3050	3957.2775	3371.0142	7976.7935	14342.2924	6516.0044	8056.4729	13191.3677	9911.3099	8017.8757	2711.5848	5645.2390	5493.2968	12657.9583	6480.3902	8721.2727	7328.2917	6298.6970	12221.4770	23432.1552	18102.4885	24167.2816	16172.7816	18933.8408	3600.0965	8000.2144	8990.7172	3904.8666	6715.3800	10219.6358	10046.4217	12578.0133	8247.6592
18_1_SM	SM 18:1;O2/18:1	8177.0679	6737.1037	6412.6448	6661.6795	5534.7973	5802.5097	4681.8533	6822.5739	8324.7921	7072.9436	14128.0037	9100.4507	8002.8882	5516.7380	6958.0479	3180.8219	4622.1318	4241.0959	2754.1971	5202.3723	2730.6569	5296.5328	5858.3510	7509.3066	6802.2534	5591.5960	6961.2805	5698.8110	7020.2744	5474.6341	3365.2174	2144.3001	6104.5864	4165.4825	980.8378	2241.7683	3268.2622	1510.2439	3787.4085	3079.4817	4077.9440	1799.2761	1214.0444	2384.5077	989.9131	1225.0231	6089.3484	4140.0416	2575.2311	1394.9168	2451.8836	1938.3134	5549.8716	2816.3527	2103.9812	1989.1423	2471.7153	1447.7190	1200.5474	919.2427	3016.3839	4965.7476	2072.4814	2513.6532	5304.3213	3657.6220	4247.5610	849.5122	2642.9268	2076.5854	4949.5656	2266.2162	3156.5154	2565.0579	3312.1622	4891.1506	8432.0933	8074.4224	6232.4168	8941.7745	5798.3733	1176.2414	3263.6558	2087.4144	1555.6207	2377.5547	2577.6460	3001.3686	3672.2628	2742.4270
24_0_SM	SM 18:1;O2/24:0	33700.1944	20997.2473	22130.1633	20383.0452	14966.9789	16714.0970	16189.9616	16946.1915	22368.9728	17115.6534	24487.2467	32639.6987	19742.3131	22575.0751	24941.8168	16949.5120	14673.7988	13144.5195	8980.2200	17710.6742	10024.6957	14872.4251	31107.8717	14758.8951	26865.8892	16850.0972	27429.9299	20875.8759	12865.3654	20390.3904	12843.7804	6186.2245	18735.4227	13197.2789	3912.0505	10377.2522	12258.5085	4527.1522	7452.2022	9224.2242	6522.5744	2841.9789	2294.5485	9958.5735	4018.3718	6592.0685	10252.4458	15759.9581	9744.0601	4278.9133	6590.4655	7336.8994	15110.7357	11232.9204	7009.1967	6686.9148	6584.7378	4507.1395	4268.7266	4529.8455	10051.1419	11017.3712	9308.7949	7258.5034	14257.7745	13472.2222	7209.4595	5194.6947	6262.7628	4794.1692	18111.7916	4228.0259	10715.6580	4950.1681	6930.2354	12624.9127	14743.1866	13556.9532	13980.6080	10337.1768	11688.0631	3404.4670	9303.1156	5825.8258	3641.1411	8106.0393	6527.9728	7901.6854	8435.2762	5710.5571
24_1_SM	SM 18:1;O2/24:1	69588.3576	39853.3181	40684.0737	47880.2817	30371.3976	27934.8862	36151.0292	32527.0049	36721.2766	34752.5368	48704.9100	87746.5697	45623.4043	40395.8955	42737.6866	26735.4478	27125.7463	18695.2985	21645.6938	33532.0574	18392.5837	36534.9282	47189.6050	37786.1244	40122.0374	35664.0333	36861.3272	36143.2494	43922.4256	27526.3158	44362.5780	28922.6611	42514.1372	33706.8607	21202.7027	36382.6087	25372.0824	16276.4302	24654.0046	24414.6453	25158.3965	13542.4702	12069.2308	24138.4615	13599.1333	12326.0229	28418.3306	53755.1555	30558.2651	12069.2308	23808.2090	26150	53275.7463	26735.4478	17992.7612	18142.3445	27025.8373	14388.7560	18392.5837	12111.5789	23051.1434	46537.2141	29248.8566	23159.8753	35337.8378	36741.6476	26329.5194	16994.5080	19747.1396	13882.8375	49636.8364	18018.8516	21531.9610	18075.5146	21248.6457	26107.2013	43226.6776	46821.7676	38347.6268	28675.1227	33760.8209	15085.0373	12489.5522	22051.8657	10850.2985	20894.9761	23022.0096	24273.2057	23397.3684	24523.4450
C14_Ceramide	Cer 18:1;O2/14:0	7.4964	11.1642	16.0407	11.2645	9.1018	11.1744	12.0756	10.7385	11.4258	12.7144	10.3090	8.4151	9.3640	13.0425	12.7333	8.7143	12.1923	10.1635	5.9446	5.3747	5.0799	5.8365	7.9518	7.9392	7.3651	9.5731	8.6299	11.8340	4.3540	11.2758	14.4368	5.2652	6.4618	7.5195	7.7974	9.5007	19.7606	5.4370	10.5055	9.1546	16.4012	11.8052	8.4619	12.8866	12.2558	7.1304	10.8244	10.9103	7.0445	12.8862	17.1967	15.3611	9.1973	9.4099	13.1197	7.4872	7.2318	9.2264	5.5122	8.4993	9.4959	10.6539	6.1453	3.9682	6.2843	10.4162	12.0573	3.4051	7.5023	12.1690	10.1832	6.1640	8.1736	9.4622	9.4622	9.1922	9.9654	10.3949	7.0531	11.2540	10.7238	17.6605	6.6661	10.2601	5.6421	5.4042	8.3912	6.8977	5.0406	4.6771
C16_Ceramide	Cer 18:1;O2/16:0	207.9768	211.5376	326.8702	206.0704	168.9619	198.1750	205.2808	188.0617	213.4540	174.5720	224.5631	173.3140	223.7696	251.4622	279.5863	203.4859	264.6970	191.9054	172.4845	225.9304	131.1854	212.5689	163.6855	293.9524	182.9426	204.1254	255.2355	192.6680	118.1830	192.6680	1193.9411	184.8683	405.3622	346.6280	248.4168	295.9540	504.5122	254.2423	450.8829	480.6769	526.6243	370.2950	424.7734	562.9432	363.1892	318.1972	369.7753	434.8430	369.7753	618.9372	694.8298	627.0011	532.7028	375.5389	367.2672	428.7819	730.0224	392.3415	323.1047	258.7267	221.4568	540.1620	163.6855	210.8654	275.3767	321.7755	490.6083	95.1423	268.1462	429.0340	947.4500	251.0743	450.0387	177.6469	300.0258	245.1943	285.6633	452.3003	616.5567	588.7838	464.8742	400.3543	258.0796	572.4074	266.3514	258.7267	437.2846	225.9304	242.9359	438.4993
C18_1_Ceramide	Cer 18:1;O2/18:1	16.1460	24.0825	29.4982	18.8484	16.4818	23.3281	13.4390	16.1381	17.0159	17.2860	27.2794	15.5986	17.2860	18.0744	26.3237	11.6232	25.9530	18.2227	11.0134	12.1598	8.9888	19.0264	10.9464	22.6854	17.5143	19.6123	18.4026	12.2684	11.9276	21.1289	33.5690	8.5564	24.5382	17.4230	5.1357	6.7931	38.7364	7.6678	16.3579	16.5851	27.2161	16.5663	12.1712	13.4390	9.2974	9.5208	14.4500	10.1960	8.4404	12.8969	23.1723	13.9775	30.7728	16.0538	20.2062	11.4403	12.6843	14.8797	7.1227	4.0492	10.5815	28.3695	3.3387	6.6773	17.9704	14.1996	30.1031	3.0557	17.4939	16.9259	32.5410	9.2974	14.7914	10.9879	13.6926	11.3439	13.2346	16.2731	26.6717	40.7165	22.9869	23.5430	19.2793	19.6501	10.0290	10.0621	12.3184	11.4890	10.5499	16.2213
C18_Ceramide	Cer 18:1;O2/18:0	71.8163	84.6562	228.1312	76.2707	105.6667	102.3753	75.3627	122.3503	113.6730	149.2500	205.6526	67.3367	156.1919	109.2649	148.5558	93.0209	133.7002	103.8502	93.3782	73.4610	78.1170	148.7327	52.3335	151.3193	95.9921	111.6353	63.5625	55.6875	49.7812	110.6250	647.7692	91.7258	195.5395	135.1000	36.4770	30.7500	190.3125	93.0938	132.1875	199.6875	276.9354	250.8308	179.3270	152.0875	161.1673	149.2500	209.9913	154.4564	156.1919	266.3939	173.5465	132.4507	281.8395	169.3814	194.3721	84.8423	144.8527	139.6794	116.7875	31.0399	79.6379	396.7675	30.1486	115.1906	154.2985	135	143.4375	18.7500	169.6875	195.9375	365.4639	81.9456	149.8175	98.2894	135.0627	131.8953	170.9433	200.4462	688.9797	510.2267	265.1791	176.3233	170.7698	304.0535	105.7940	123.7714	223.7457	140.9727	204.3458	262.5455
C20_Ceramide	Cer 18:1;O2/20:0	128.2233	101.5233	303.0824	87.5790	118.0841	104.3076	74.7866	150.7430	160.5546	186.4218	203.3692	78.3994	173.0422	110.9649	174.6802	89.0582	139.8873	113.2557	92.6056	87.4995	83.5539	149.7008	87.1918	163.6265	139.2138	161.9277	111.9742	85.3137	49.9085	143.9668	361.2233	64.6978	188.3050	144.3428	30.0409	33.8055	163.1624	63.5587	82.0078	138.6347	115.1320	148.5891	76.5578	105.2916	79.8051	99.0087	191.7736	126.6598	109.7123	122.1999	72.4493	88.1992	177.5438	132.7283	114.6875	55.8187	101.7733	97.1315	67.1913	23.9057	94.5189	262.3082	35.0965	97.4497	141.4119	129.0370	94.4849	26.2340	133.3026	120.5056	293.2421	48.2177	113.1639	69.7680	85.6109	99.9007	173.9342	145.3911	319.3253	369.2756	168.9529	102.5172	91.9219	167.5211	61.7108	72.0653	138.0961	99.3363	102.0054	156.6636
C24_1_Ceramide	Cer 18:1;O2/24:1	1349.7910	700.4864	2676.8363	1046.0252	897.7697	789.0490	812.1109	1147.2316	1052.3478	1017.8446	1500.8894	1108.1618	1630.2764	749.1960	1123.0432	624.5802	795.7392	463.9310	665.0917	650.7531	502.9549	1411.8033	707.3905	1191.2090	841.5364	1124.8259	1132.7263	953.5049	729.7709	1125.6980	2807.8986	719.8885	1683.0728	1758.0611	644.0670	698.1436	1757.0729	838.7095	1153.8112	1815.6420	1474.3191	1235.4629	1004.8432	1400.1913	1153.0987	814.2756	1768.2893	2061.5665	1440.5088	1216.2380	1034.4609	882.8201	1906.7713	1071.9958	687.6388	644.1352	1202.2387	1158.1199	815.0958	340.8181	714.0561	3349.4814	452.4300	941.5209	1074.8336	1569.6518	1593.0794	372.4995	1300.2340	928.9059	4315.8837	873.0604	1153.0987	848.3512	971.8975	940.2123	1811.4183	1940.8053	2277.2115	3234.6755	1216.1297	1177.0934	539.0007	1214.6283	668.1206	751.1235	1466.9518	905.5394	712.5195	1367.6844
C24_Ceramide	Cer 18:1;O2/24:0	3071.9865	2081.8905	5926.7569	2158.4010	2600.6963	2547.6209	2149.5551	3083.6143	4406.6515	2052.2703	5323.4017	1963.2997	2979.4381	2202.4949	3577.3006	2090.2658	2216.5235	1921.9223	1491.7310	2178.7124	1678.1974	3336.7668	2548.4400	2581.0873	2771.7172	2502.2447	3515.3234	2138.7728	1036.3947	3822.4876	1547.5421	469.6521	2201.9753	2340.5612	448.8642	728.0929	1717.8441	596.1260	1097.8275	1695.0912	1716.1057	719.1721	624.5210	2061.0961	1273.8104	927.1678	1791.8299	1156.3554	1343.8724	930.2931	707.0429	531.6851	1697.4642	1795.6646	613.0511	621.2275	1050.1001	877.3734	468.1288	453.4077	597.4590	1924.8036	556.6532	823.8159	2047.9910	1581.3267	1051.1841	340.1559	1058.0099	845.2703	3405.6738	675.8272	2370.7028	1052.6628	1300.3482	1760.5771	2812.7563	2177.2817	2771.0858	4156.6287	1697.4642	705.6401	1262.5767	918.8753	662.1513	981.4020	1413.2189	1334.7067	978.4578	869.5222
SA	Sphinganine	2.2400	3.6700	0.2730	0.4770	3.4100	6	7.1400	3.1100	7.3400	5.7200	11.1000	14.2000	4.6200	2.5600	5.2000	3.8900	3.8300	4	5.9700	6.3600	5.0500	8.3400	6.5100	4	11.1000	11	2.6600	3.3800	4.4200	2.9000	70.4000	5.8300	14.2000	18.9000	3.9000	6.3400	12.1000	1.3500	12.9000	5.0800	2.0200	0.1960	19.4000	5.6300	10.2000	3.8800	5.7300	12.2000	1.3800	22.9000	10.2000	5.6300	7.5600	2.4700	4.5700	22.4000	5.7600	7.3200	1.4900	14.2000	11.3000	45.6000	9.1600	19.4000	10.4000	2.5000	5.5700	4.1100	3.1600	0.2550	10.1000	0.5000	6.6100	1.8500	2.6800	2.9500	2.5000	0.2510	5.6500	4.0500	2.5100	3.9600	2.4800	2.1800	1.3800	3.9300	3.3000	1.2400	0.9040	6.7700
SO	Sphingosine	12.8136	7.0513	30.9244	21.0349	20.8779	25.9012	40.0291	8.7644	15.7500	11.8588	27.9794	15.2777	14.9162	7.0665	11.3148	15.2826	12.9412	13.9787	10.9176	10.0227	7.3381	6.4253	17.6802	8.7520	17.3722	29.3233	7.6179	11.8125	7.4853	14.5848	86.2451	16.3866	15.4625	16.0786	14.3537	34.3527	46.0446	11.2460	59.6652	30.7366	14.7401	35.7907	84.9244	44.2674	45.5233	10.6544	20.1044	38.8191	4.9103	75.8779	37.4355	26.6395	27.4807	18.3672	22.9941	58.7045	8.6804	16.4659	3.0068	31.7685	3.5176	36.0997	14.7233	19.0971	8.8709	9.6429	22.0580	8.8232	19.4062	13.7411	65.3023	22.6047	27.9419	11.3180	8.1471	8.6440	3.4187	4.5582	23.4397	12.6000	14.0068	11.3007	15.0022	21.8724	10.2632	6.1747	5.2530	1.5034	4.3581	24.7884