Metabolite_name RefMet_name D_Serum_1 D_Serum_10 D_Serum_11 D_Serum_12 D_Serum_13 D_Serum_14 D_Serum_15 D_Serum_16 D_Serum_17 D_Serum_18 D_Serum_19 D_Serum_2 D_Serum_20 D_Serum_21 D_Serum_22 D_Serum_23 D_Serum_24 D_Serum_25 D_Serum_26 D_Serum_27 D_Serum_28 D_Serum_29 D_Serum_3 D_Serum_30 D_Serum_4 D_Serum_5 D_Serum_6 D_Serum_7 D_Serum_8 D_Serum_9 C_Serum_61 C_Serum_62 C_Serum_63 C_Serum_64 C_Serum_65 C_Serum_66 C_Serum_67 C_Serum_68 C_Serum_69 C_Serum_70 C_Serum_71 C_Serum_72 C_Serum_73 C_Serum_74 C_Serum_75 C_Serum_76 C_Serum_77 C_Serum_78 C_Serum_79 C_Serum_80 C_Serum_81 C_Serum_82 C_Serum_83 C_Serum_84 C_Serum_85 C_Serum_86 C_Serum_87 C_Serum_88 C_Serum_89 C_Serum_90 B_Serum_31 B_Serum_32 B_Serum_33 B_Serum_34 B_Serum_35 B_Serum_36 B_Serum_37 B_Serum_38 B_Serum_39 B_Serum_40 B_Serum_41 B_Serum_42 B_Serum_43 B_Serum_44 B_Serum_45 B_Serum_46 B_Serum_47 B_Serum_48 B_Serum_49 B_Serum_50 B_Serum_51 B_Serum_52 B_Serum_53 B_Serum_54 B_Serum_55 B_Serum_56 B_Serum_57 B_Serum_58 B_Serum_59 B_Serum_60 Factors - Factor:Control Factor:Control Factor:Control Factor:Control Factor:Control Factor:Control Factor:Control Factor:Control Factor:Control Factor:Control Factor:Control Factor:Control Factor:Control Factor:Control Factor:Control Factor:Control Factor:Control Factor:Control Factor:Control Factor:Control Factor:Control Factor:Control Factor:Control Factor:Control Factor:Control Factor:Control Factor:Control Factor:Control Factor:Control Factor:Control Factor:eARDS Factor:eARDS Factor:eARDS Factor:eARDS Factor:eARDS Factor:eARDS Factor:eARDS Factor:eARDS Factor:eARDS Factor:eARDS Factor:eARDS Factor:eARDS Factor:eARDS Factor:eARDS Factor:eARDS Factor:eARDS Factor:eARDS Factor:eARDS Factor:eARDS Factor:eARDS Factor:eARDS Factor:eARDS Factor:eARDS Factor:eARDS Factor:eARDS Factor:eARDS Factor:eARDS Factor:eARDS Factor:eARDS Factor:eARDS Factor:pARDS Factor:pARDS Factor:pARDS Factor:pARDS Factor:pARDS Factor:pARDS Factor:pARDS Factor:pARDS Factor:pARDS Factor:pARDS Factor:pARDS Factor:pARDS Factor:pARDS Factor:pARDS Factor:pARDS Factor:pARDS Factor:pARDS Factor:pARDS Factor:pARDS Factor:pARDS Factor:pARDS Factor:pARDS Factor:pARDS Factor:pARDS Factor:pARDS Factor:pARDS Factor:pARDS Factor:pARDS Factor:pARDS Factor:pARDS 16_0_SM SM 18:1;O2/16:0 88702.4496 58064.1099 65529.1451 62568.4909 48817.8972 47699.4279 52107.5129 48512.2777 54447.2904 48426.2631 68123.6240 73674.7518 58662.0096 73218.0047 77827.3706 47689.2088 49639.3252 43966.2594 34556.8874 62967.7511 35716.5145 52878.9954 65965.7381 71548.9916 57280.8998 49669.4685 73647.9167 62335.2273 49637.3106 46982.2917 58354.3068 33763.5287 49767.0509 44595.1809 30152.9779 54947.3485 38555.4924 27589.1099 51830.5871 40979.6401 39672.7655 22764.1408 22632.5561 48817.8972 23224.6870 24944.2563 46791.9842 59694.1857 44899.6613 35266.0175 47334.6422 49284.7586 71267.8883 53184.9913 31556.4282 41514.6499 65982.7816 30266.2671 33629.1857 20989.2504 35129.6830 49083.9737 46741.9949 34544.1883 51035.6228 48482.9546 45250.7576 25280.3977 26434.7538 29089.7727 74345.3152 31448.7262 50067.9512 28817.0337 36185.7729 44899.6613 55221.4225 56597.6574 49114.3805 44211.5439 72863.4380 21096.7132 31024.5782 40243.3101 20210.2967 36992.1043 47660.6735 39775.2093 40007.1347 37224.0297 18_0_SM SM 18:1;O2/18:0 17175.3378 11465.7961 13081.9091 13081.9091 11810.0568 10295.9470 9750.8674 13783.6207 13416.0575 12956.6035 24351.0632 16644.1417 16448.4540 16419.4877 17600.4718 9828.8349 11219.3483 11371.7334 7195.0500 13457.4083 8047.7967 13017.7108 12748.7043 16921.6917 14342.2924 13102.8350 12272.2588 11465.7961 12389.1374 11115.1601 9118.8649 7684.6357 11774.8450 9472.9956 2965.8444 6720.5227 7433.4825 3962.1864 7702.3034 7445.1703 8781.8371 5953.4799 3791.3311 6722.6477 3688.3716 4511.8385 11762.0230 11578.2414 8426.3868 4824.2672 6476.3641 5314.4282 14628.9636 9124.0541 6228.7384 5849.3092 5982.5508 3917.3050 3957.2775 3371.0142 7976.7935 14342.2924 6516.0044 8056.4729 13191.3677 9911.3099 8017.8757 2711.5848 5645.2390 5493.2968 12657.9583 6480.3902 8721.2727 7328.2917 6298.6970 12221.4770 23432.1552 18102.4885 24167.2816 16172.7816 18933.8408 3600.0965 8000.2144 8990.7172 3904.8666 6715.3800 10219.6358 10046.4217 12578.0133 8247.6592 18_1_SM SM 18:1;O2/18:1 8177.0679 6737.1037 6412.6448 6661.6795 5534.7973 5802.5097 4681.8533 6822.5739 8324.7921 7072.9436 14128.0037 9100.4507 8002.8882 5516.7380 6958.0479 3180.8219 4622.1318 4241.0959 2754.1971 5202.3723 2730.6569 5296.5328 5858.3510 7509.3066 6802.2534 5591.5960 6961.2805 5698.8110 7020.2744 5474.6341 3365.2174 2144.3001 6104.5864 4165.4825 980.8378 2241.7683 3268.2622 1510.2439 3787.4085 3079.4817 4077.9440 1799.2761 1214.0444 2384.5077 989.9131 1225.0231 6089.3484 4140.0416 2575.2311 1394.9168 2451.8836 1938.3134 5549.8716 2816.3527 2103.9812 1989.1423 2471.7153 1447.7190 1200.5474 919.2427 3016.3839 4965.7476 2072.4814 2513.6532 5304.3213 3657.6220 4247.5610 849.5122 2642.9268 2076.5854 4949.5656 2266.2162 3156.5154 2565.0579 3312.1622 4891.1506 8432.0933 8074.4224 6232.4168 8941.7745 5798.3733 1176.2414 3263.6558 2087.4144 1555.6207 2377.5547 2577.6460 3001.3686 3672.2628 2742.4270 24_0_SM SM 18:1;O2/24:0 33700.1944 20997.2473 22130.1633 20383.0452 14966.9789 16714.0970 16189.9616 16946.1915 22368.9728 17115.6534 24487.2467 32639.6987 19742.3131 22575.0751 24941.8168 16949.5120 14673.7988 13144.5195 8980.2200 17710.6742 10024.6957 14872.4251 31107.8717 14758.8951 26865.8892 16850.0972 27429.9299 20875.8759 12865.3654 20390.3904 12843.7804 6186.2245 18735.4227 13197.2789 3912.0505 10377.2522 12258.5085 4527.1522 7452.2022 9224.2242 6522.5744 2841.9789 2294.5485 9958.5735 4018.3718 6592.0685 10252.4458 15759.9581 9744.0601 4278.9133 6590.4655 7336.8994 15110.7357 11232.9204 7009.1967 6686.9148 6584.7378 4507.1395 4268.7266 4529.8455 10051.1419 11017.3712 9308.7949 7258.5034 14257.7745 13472.2222 7209.4595 5194.6947 6262.7628 4794.1692 18111.7916 4228.0259 10715.6580 4950.1681 6930.2354 12624.9127 14743.1866 13556.9532 13980.6080 10337.1768 11688.0631 3404.4670 9303.1156 5825.8258 3641.1411 8106.0393 6527.9728 7901.6854 8435.2762 5710.5571 24_1_SM SM 18:1;O2/24:1 69588.3576 39853.3181 40684.0737 47880.2817 30371.3976 27934.8862 36151.0292 32527.0049 36721.2766 34752.5368 48704.9100 87746.5697 45623.4043 40395.8955 42737.6866 26735.4478 27125.7463 18695.2985 21645.6938 33532.0574 18392.5837 36534.9282 47189.6050 37786.1244 40122.0374 35664.0333 36861.3272 36143.2494 43922.4256 27526.3158 44362.5780 28922.6611 42514.1372 33706.8607 21202.7027 36382.6087 25372.0824 16276.4302 24654.0046 24414.6453 25158.3965 13542.4702 12069.2308 24138.4615 13599.1333 12326.0229 28418.3306 53755.1555 30558.2651 12069.2308 23808.2090 26150 53275.7463 26735.4478 17992.7612 18142.3445 27025.8373 14388.7560 18392.5837 12111.5789 23051.1434 46537.2141 29248.8566 23159.8753 35337.8378 36741.6476 26329.5194 16994.5080 19747.1396 13882.8375 49636.8364 18018.8516 21531.9610 18075.5146 21248.6457 26107.2013 43226.6776 46821.7676 38347.6268 28675.1227 33760.8209 15085.0373 12489.5522 22051.8657 10850.2985 20894.9761 23022.0096 24273.2057 23397.3684 24523.4450 C14_Ceramide Cer 18:1;O2/14:0 7.4964 11.1642 16.0407 11.2645 9.1018 11.1744 12.0756 10.7385 11.4258 12.7144 10.3090 8.4151 9.3640 13.0425 12.7333 8.7143 12.1923 10.1635 5.9446 5.3747 5.0799 5.8365 7.9518 7.9392 7.3651 9.5731 8.6299 11.8340 4.3540 11.2758 14.4368 5.2652 6.4618 7.5195 7.7974 9.5007 19.7606 5.4370 10.5055 9.1546 16.4012 11.8052 8.4619 12.8866 12.2558 7.1304 10.8244 10.9103 7.0445 12.8862 17.1967 15.3611 9.1973 9.4099 13.1197 7.4872 7.2318 9.2264 5.5122 8.4993 9.4959 10.6539 6.1453 3.9682 6.2843 10.4162 12.0573 3.4051 7.5023 12.1690 10.1832 6.1640 8.1736 9.4622 9.4622 9.1922 9.9654 10.3949 7.0531 11.2540 10.7238 17.6605 6.6661 10.2601 5.6421 5.4042 8.3912 6.8977 5.0406 4.6771 C16_Ceramide Cer 18:1;O2/16:0 207.9768 211.5376 326.8702 206.0704 168.9619 198.1750 205.2808 188.0617 213.4540 174.5720 224.5631 173.3140 223.7696 251.4622 279.5863 203.4859 264.6970 191.9054 172.4845 225.9304 131.1854 212.5689 163.6855 293.9524 182.9426 204.1254 255.2355 192.6680 118.1830 192.6680 1193.9411 184.8683 405.3622 346.6280 248.4168 295.9540 504.5122 254.2423 450.8829 480.6769 526.6243 370.2950 424.7734 562.9432 363.1892 318.1972 369.7753 434.8430 369.7753 618.9372 694.8298 627.0011 532.7028 375.5389 367.2672 428.7819 730.0224 392.3415 323.1047 258.7267 221.4568 540.1620 163.6855 210.8654 275.3767 321.7755 490.6083 95.1423 268.1462 429.0340 947.4500 251.0743 450.0387 177.6469 300.0258 245.1943 285.6633 452.3003 616.5567 588.7838 464.8742 400.3543 258.0796 572.4074 266.3514 258.7267 437.2846 225.9304 242.9359 438.4993 C18_1_Ceramide Cer 18:1;O2/18:1 16.1460 24.0825 29.4982 18.8484 16.4818 23.3281 13.4390 16.1381 17.0159 17.2860 27.2794 15.5986 17.2860 18.0744 26.3237 11.6232 25.9530 18.2227 11.0134 12.1598 8.9888 19.0264 10.9464 22.6854 17.5143 19.6123 18.4026 12.2684 11.9276 21.1289 33.5690 8.5564 24.5382 17.4230 5.1357 6.7931 38.7364 7.6678 16.3579 16.5851 27.2161 16.5663 12.1712 13.4390 9.2974 9.5208 14.4500 10.1960 8.4404 12.8969 23.1723 13.9775 30.7728 16.0538 20.2062 11.4403 12.6843 14.8797 7.1227 4.0492 10.5815 28.3695 3.3387 6.6773 17.9704 14.1996 30.1031 3.0557 17.4939 16.9259 32.5410 9.2974 14.7914 10.9879 13.6926 11.3439 13.2346 16.2731 26.6717 40.7165 22.9869 23.5430 19.2793 19.6501 10.0290 10.0621 12.3184 11.4890 10.5499 16.2213 C18_Ceramide Cer 18:1;O2/18:0 71.8163 84.6562 228.1312 76.2707 105.6667 102.3753 75.3627 122.3503 113.6730 149.2500 205.6526 67.3367 156.1919 109.2649 148.5558 93.0209 133.7002 103.8502 93.3782 73.4610 78.1170 148.7327 52.3335 151.3193 95.9921 111.6353 63.5625 55.6875 49.7812 110.6250 647.7692 91.7258 195.5395 135.1000 36.4770 30.7500 190.3125 93.0938 132.1875 199.6875 276.9354 250.8308 179.3270 152.0875 161.1673 149.2500 209.9913 154.4564 156.1919 266.3939 173.5465 132.4507 281.8395 169.3814 194.3721 84.8423 144.8527 139.6794 116.7875 31.0399 79.6379 396.7675 30.1486 115.1906 154.2985 135 143.4375 18.7500 169.6875 195.9375 365.4639 81.9456 149.8175 98.2894 135.0627 131.8953 170.9433 200.4462 688.9797 510.2267 265.1791 176.3233 170.7698 304.0535 105.7940 123.7714 223.7457 140.9727 204.3458 262.5455 C20_Ceramide Cer 18:1;O2/20:0 128.2233 101.5233 303.0824 87.5790 118.0841 104.3076 74.7866 150.7430 160.5546 186.4218 203.3692 78.3994 173.0422 110.9649 174.6802 89.0582 139.8873 113.2557 92.6056 87.4995 83.5539 149.7008 87.1918 163.6265 139.2138 161.9277 111.9742 85.3137 49.9085 143.9668 361.2233 64.6978 188.3050 144.3428 30.0409 33.8055 163.1624 63.5587 82.0078 138.6347 115.1320 148.5891 76.5578 105.2916 79.8051 99.0087 191.7736 126.6598 109.7123 122.1999 72.4493 88.1992 177.5438 132.7283 114.6875 55.8187 101.7733 97.1315 67.1913 23.9057 94.5189 262.3082 35.0965 97.4497 141.4119 129.0370 94.4849 26.2340 133.3026 120.5056 293.2421 48.2177 113.1639 69.7680 85.6109 99.9007 173.9342 145.3911 319.3253 369.2756 168.9529 102.5172 91.9219 167.5211 61.7108 72.0653 138.0961 99.3363 102.0054 156.6636 C24_1_Ceramide Cer 18:1;O2/24:1 1349.7910 700.4864 2676.8363 1046.0252 897.7697 789.0490 812.1109 1147.2316 1052.3478 1017.8446 1500.8894 1108.1618 1630.2764 749.1960 1123.0432 624.5802 795.7392 463.9310 665.0917 650.7531 502.9549 1411.8033 707.3905 1191.2090 841.5364 1124.8259 1132.7263 953.5049 729.7709 1125.6980 2807.8986 719.8885 1683.0728 1758.0611 644.0670 698.1436 1757.0729 838.7095 1153.8112 1815.6420 1474.3191 1235.4629 1004.8432 1400.1913 1153.0987 814.2756 1768.2893 2061.5665 1440.5088 1216.2380 1034.4609 882.8201 1906.7713 1071.9958 687.6388 644.1352 1202.2387 1158.1199 815.0958 340.8181 714.0561 3349.4814 452.4300 941.5209 1074.8336 1569.6518 1593.0794 372.4995 1300.2340 928.9059 4315.8837 873.0604 1153.0987 848.3512 971.8975 940.2123 1811.4183 1940.8053 2277.2115 3234.6755 1216.1297 1177.0934 539.0007 1214.6283 668.1206 751.1235 1466.9518 905.5394 712.5195 1367.6844 C24_Ceramide Cer 18:1;O2/24:0 3071.9865 2081.8905 5926.7569 2158.4010 2600.6963 2547.6209 2149.5551 3083.6143 4406.6515 2052.2703 5323.4017 1963.2997 2979.4381 2202.4949 3577.3006 2090.2658 2216.5235 1921.9223 1491.7310 2178.7124 1678.1974 3336.7668 2548.4400 2581.0873 2771.7172 2502.2447 3515.3234 2138.7728 1036.3947 3822.4876 1547.5421 469.6521 2201.9753 2340.5612 448.8642 728.0929 1717.8441 596.1260 1097.8275 1695.0912 1716.1057 719.1721 624.5210 2061.0961 1273.8104 927.1678 1791.8299 1156.3554 1343.8724 930.2931 707.0429 531.6851 1697.4642 1795.6646 613.0511 621.2275 1050.1001 877.3734 468.1288 453.4077 597.4590 1924.8036 556.6532 823.8159 2047.9910 1581.3267 1051.1841 340.1559 1058.0099 845.2703 3405.6738 675.8272 2370.7028 1052.6628 1300.3482 1760.5771 2812.7563 2177.2817 2771.0858 4156.6287 1697.4642 705.6401 1262.5767 918.8753 662.1513 981.4020 1413.2189 1334.7067 978.4578 869.5222 SA Sphinganine 2.2400 3.6700 0.2730 0.4770 3.4100 6 7.1400 3.1100 7.3400 5.7200 11.1000 14.2000 4.6200 2.5600 5.2000 3.8900 3.8300 4 5.9700 6.3600 5.0500 8.3400 6.5100 4 11.1000 11 2.6600 3.3800 4.4200 2.9000 70.4000 5.8300 14.2000 18.9000 3.9000 6.3400 12.1000 1.3500 12.9000 5.0800 2.0200 0.1960 19.4000 5.6300 10.2000 3.8800 5.7300 12.2000 1.3800 22.9000 10.2000 5.6300 7.5600 2.4700 4.5700 22.4000 5.7600 7.3200 1.4900 14.2000 11.3000 45.6000 9.1600 19.4000 10.4000 2.5000 5.5700 4.1100 3.1600 0.2550 10.1000 0.5000 6.6100 1.8500 2.6800 2.9500 2.5000 0.2510 5.6500 4.0500 2.5100 3.9600 2.4800 2.1800 1.3800 3.9300 3.3000 1.2400 0.9040 6.7700 SO Sphingosine 12.8136 7.0513 30.9244 21.0349 20.8779 25.9012 40.0291 8.7644 15.7500 11.8588 27.9794 15.2777 14.9162 7.0665 11.3148 15.2826 12.9412 13.9787 10.9176 10.0227 7.3381 6.4253 17.6802 8.7520 17.3722 29.3233 7.6179 11.8125 7.4853 14.5848 86.2451 16.3866 15.4625 16.0786 14.3537 34.3527 46.0446 11.2460 59.6652 30.7366 14.7401 35.7907 84.9244 44.2674 45.5233 10.6544 20.1044 38.8191 4.9103 75.8779 37.4355 26.6395 27.4807 18.3672 22.9941 58.7045 8.6804 16.4659 3.0068 31.7685 3.5176 36.0997 14.7233 19.0971 8.8709 9.6429 22.0580 8.8232 19.4062 13.7411 65.3023 22.6047 27.9419 11.3180 8.1471 8.6440 3.4187 4.5582 23.4397 12.6000 14.0068 11.3007 15.0022 21.8724 10.2632 6.1747 5.2530 1.5034 4.3581 24.7884