Metabolite_name RefMet_name 20181221_hProdh2_OE_1_M62 20181221_hProdh2_OE_2_M62 20181221_hProdh2_OE_3_M62 20181221_hProdh2_OE_4_M62 20181221_hProdh2_OE_5_M62 20181221_hProdh2_OE_Vector1_M62 20181221_hProdh2_OE_Vector2_M62 20181221_hProdh2_OE_Vector3_M62 20181221_hProdh2_OE_Vector4_M62 20181221_hProdh2_OE_Vector5_M62 Factors - Genotype:PRODH2_OE | Treatment:PRODH2 Genotype:PRODH2_OE | Treatment:PRODH2 Genotype:PRODH2_OE | Treatment:PRODH2 Genotype:PRODH2_OE | Treatment:PRODH2 Genotype:PRODH2_OE | Treatment:PRODH2 Genotype:Vector_OE | Treatment:Control Genotype:Vector_OE | Treatment:Control Genotype:Vector_OE | Treatment:Control Genotype:Vector_OE | Treatment:Control Genotype:Vector_OE | Treatment:Control 2-Hydroxy-Glutarate 2-Hydroxyglutaric acid 19140 20065 17383 27650 5763 43202 3879 25582 43366 6616 3-Phosphoserine Phosphoserine 1968 3001 878 6420 2976 2051 722 2442 2808 646 4-Hydroxy-Glutamate Erythro-4-hydroxy-glutamic acid 951 1208 3492 4155 3755 6300 3382 2946 6041 2656 4-Hydroxyproline cis-4-Hydroxyproline 47082 60066 68003 51383 65504 111449 156937 116312 138532 175782 Anserine Anserine 1072 2752 1595 2533 792 6567 1036 2801 3031 1164 Arginine Arginine 824313 864002 1063356 782954 980753 1254486 888562 1063438 1210823 756655 Argininosuccinate Argininosuccinic acid 1235 3082 2542 3363 3183 3149 1984 1603 3472 2733 Aspartic acid Aspartic acid 262024 188968 206615 307343 248102 669462 550116 692076 423341 457646 Choline Choline 48604 94374 40526 58028 79363 18755 16472 26950 25612 37119 Citrulline Citrulline 2259 9008 7373 2752 3765 1853 2570 1890 2845 1435 Cystathionine Cystathionine 1167 1907 2336 3702 1116 2440 1871 2619 2800 1226 Cysteine Cysteine 8145 5658 9692 17265 10735 20403 6595 1866 23348 6201 Cystine Cystine 6809 7638 10820 10351 5970 3314 490 1438 9123 3205 Fumarate Fumaric acid 371169 206622 146301 155752 103204 124135 75114 198665 291479 92950 Glutamate Glutamic acid 1135091 1417242 1676107 1776951 1031736 355124 141338 253678 447163 509152 Glutamine Glutamine 817893 998139 1343620 1379413 701559 2177009 887833 1772151 2489780 985467 Glutathione Glutathione 1470537 911867 1597407 762426 1431081 921413 604123 487883 1620478 1019804 Glyine 669 1552 1107 1336 994 2772 1545 1595 2009 1133 Glyoxylate Glyoxylic acid 3193 1450 1596 1384 1564 1430 1022 1717 1959 2434 Guanine Guanine 25574 38572 18967 24089 25096 20808 24335 13872 13608 10681 Histidine Histidine 816556 964912 997551 922590 1012593 1771187 1079282 1450365 1706363 1125901 Homocystine Homocystine 288 2058 1325 984 1394 473 449 875 1629 1120 Lactate Lactic acid 2297 1858 1654 2148 1805 1774 993 1183 749 762 Leucine Leucine 729055 698269 498362 465365 626195 925260 654986 1314280 2172796 1108789 Lysine Lysine 1739 4982 2612 1182 1913 1537 1637 2687 3865 2384 Malate Malic acid 2466 1588 3451 4448 2989 3476 5557 5757 5807 5391 Methionine Methionine 9992 31879 34112 32449 17776 28378 14648 44762 55402 20079 Ornithine Ornithine 29229 18443 23510 21021 19829 74512 39949 77101 96890 37660 Oxaloacetate Oxaloacetic acid 44026 45214 34558 28376 36482 51981 44469 72558 97556 69089 Oxo-glutarate 2-Oxoglutaric acid 24202 21136 34484 38906 18712 67864 21720 48780 72103 31016 Oxoproline Oxoproline 445316 96070 214330 230874 136518 1735415 1454747 983490 1352858 816916 PHC 3957 3094 3554 4512 3806 1401 2604 1719 2412 1132 Phenylalanine Phenylalanine 122000 143264 157312 149922 182668 339919 198992 187418 194564 160759 Proline Proline 2543357 4455294 3259016 3462500 2358333 2823719 3638626 4286561 6440219 3087870 Pyruvate Pyruvic acid 1167 858 1160 805 825 3121 2563 1871 1473 2384 Spermidine Spermidine 206822 515459 327648 93700 273430 107887 111647 330073 548680 215443 Spermine Spermine 265372 139276 76612 48855 43190 42471 36872 159882 221133 87789 Sphinganine Sphinganine 43878 22062 20403 35196 39059 32621 25332 30326 39073 31656 Succinate Succinic acid 14492 10502 14282 7773 11305 10719 12032 8978 3968 4207 Taurine Taurine 25812 52821 676736 145371 255438 285448 501681 55922 192604 575081 Threonine Threonine 580 1550 3087 923 1124 1129 2326 3357 2629 399 Tryptophan Tryptophan 19105 16018 17618 16552 26498 14206 17648 19085 16338 11956 Tyrosne 75233 44268 47975 46778 49910 264182 42504 61903 73028 43442 Valine Valine 117614 123922 582183 286282 388072 435192 414758 168393 170461 166457