metabolite_name sample1 sample2 sample3 sample4 sample5 sample6 sample7 sample8 sample9 sample10 sample11 sample12 sample13 sample14 sample15 sample16 sample17 sample18 sample19 sample20 sample21 sample22 sample23 sample24 sample25 sample26 sample27 sample28 sample29 sample30 sample31 sample32 sample33 sample34 sample35 sample36 sample37 sample38 sample39 sample40 sample41 sample42 sample43 sample44 sample45 sample46 sample47 sample48 sample49 sample50 sample51 sample52 sample53 sample54 sample55 sample56 sample57 sample58 Citrate 129.409 151.45 132.09 160.582 139.822 240.655 150.787 161.508 206.101 111.822 151.149 161.742 121.657 128.015 212.104 161.439 140.06 155.595 154.462 137.393 97.643 154.683 156.613 146.307 159.329 153.502 128.017 158.248 169.83 121.615 165.4 134.54 101.11 182.76 146.54 151.19 135.915 120.29 121.44 160.7 138.44 151 143.61 176.203 140.49 146.08 145.09 146.63 143.91 106.71 137.517 139.24 120.96 125.09 171.23 130.4 111.603 106.19 cis.Aconitate 7.016 6.715 8.198 6.811 8.733 8.616 8.088 7.312 10.19 6.864 9.68 11.902 11.789 8.937 11.614 12.388 9.276 9.012 10.06 8.776 9.095 9.349 10.314 9.595 9.435 9.371 9.847 8.88 12.047 10.757 NA 9.71 8.35 8.23 8.49 7.71 3.824 8.37 7.61 9.43 8.84 9.69 8.93 4.636 8.26 8.81 7.22 9.26 9.95 9.46 4.447 8.01 9.4 8.89 11.61 6.42 4.853 8.53 Isocitrate 5.174 4.823 3.193 4.693 3.529 8.331 5.241 6.378 6.651 5.752 2.368 5.993 1.16 5.479 9.255 6.631 6.755 6.608 5.65 7.009 NA 3.999 5.607 2.916 4.518 6.191 4.886 5.016 NA 5.537 5.37 5.39 3.81 5.85 6.1 4.66 5.568 3.71 6.2 6.81 6.75 6.08 5.79 6.512 4.26 5.89 6.07 4.53 1.98 5.48 5.69 7.85 1.56 2.28 4.65 1.51 3.653 2.56 Ketoglutarate 17.043 7.759 9.32 8.77 12.235 14.028 10.882 13.581 13.709 7.695 12.939 15.085 9.809 12.485 11.337 15.079 8.577 12.148 12.049 10.911 10.316 14.67 21.656 10.782 11.113 14.517 11.444 13.338 12.055 9.916 8.65 8.25 11.11 11.4 9.77 13.78 9.407 12.68 9.93 9.19 10.91 9.69 9.96 10.064 10.56 12.71 10.59 8.67 13.38 11.06 9.434 13.44 11.26 9.7 13.28 12.43 7.275 8.7 succinate 4.163 2.579 2.817 2.607 3.253 4.951 3.258 3.821 3.809 2.495 3.749 4.896 4.6 3.405 4.523 4.874 2.616 3.459 3.437 2.896 2.739 5.719 4.683 3.454 4.082 5.88 4.388 5.7 5.643 3.055 4.59 2.43 5.14 4.08 2.82 5.26 3.773 4.12 NA 3.08 2.94 3.25 2.72 4.711 3.84 5.18 3.72 4.61 4.03 3.74 1.802 3.28 4.66 3.21 4.14 4.54 1.17 3.91 fummarate 1.927 0.997 1.553 1.046 1.445 2.322 1.728 1.753 1.834 1.174 2.099 2.54 1.837 1.738 2.468 2.561 1.47 1.737 1.762 2.033 1.394 2.908 3.674 1.954 2.231 2.98 2.133 3.127 2.214 2.172 1.77 1.21 2.09 2.21 1.2 1.78 1.518 2.78 1.49 2.04 2.11 1.63 1.72 2.429 1.32 2.15 1.49 2.04 2.18 2.04 1.288 1.81 1.8 1.38 1.81 1.94 0.929 1.59 Malate 4.83 2.246 4.431 2.865 3.739 7.132 4.769 4.479 4.598 2.52 3.831 4.183 3.627 3.35 6.496 4.154 4.136 3.927 4.839 4.02 2.469 5.412 6.337 3.521 4.308 5.365 4.661 5.004 4.339 3.083 4.39 2.09 4.56 4.68 2.55 3.84 2.683 6.23 3.16 4.42 3.98 3.67 3.84 8.92 3.61 4.79 4.2 3.45 4.74 3.51 2.603 4.43 4.51 3.5 5.56 3.54 2.74 2.41 Oxaloacetate 0.988 0.685 0.638 0.449 1.094 0.198 0.471 1.539 0.455 0.862 1.306 1.434 1.372 1.562 1.494 1.417 0.832 0.541 0.673 0.764 1.139 1.04 1.437 1.334 1.406 1.602 1.425 1.774 1.439 1.448 NA 0.63 1.27 2.19 0.74 1.28 0.357 1.42 1.45 1.31 0.79 2.22 0.98 0.655 0.78 1.41 1.54 1.26 0.39 1.38 1.033 0.73 1.38 0.85 0.87 1.51 0.988 1.26 Aspartate 0.426 0.882 2.113 0.291 1.509 0.24 0.832 2.505 0.157 1.076 1.518 1.743 2.61 0.924 0.969 1.718 2.751 0.731 2.614 1.378 1.893 2.393 1.21 1.313 1.546 2.34 2.617 1.173 0.648 1.544 NA 0.79 0.81 1.25 0.92 0.76 0.69 1.22 1.55 2.18 1.43 0.79 0.91 1.303 3.66 1.1 1.25 2.06 1.57 1.71 1.364 1.33 1.41 1.88 1.11 1 0.54 1.26 Glutamate 119.374 86.447 118.767 74.218 120.377 23.964 39.453 369.402 31.138 133.69 288.466 261.847 234.399 155.741 99.413 273.395 195.569 157.737 180.506 170.106 435.011 332.078 422.406 346.439 300.114 382.792 214.579 234.834 60.201 593.966 NA 212.32 58.94 76.25 124.62 85.99 56.348 133.94 402.74 341.29 180.65 156.21 247.71 127.927 273.56 123.93 305.62 257.66 182.52 263.24 241.339 135.19 166.74 273.12 131.69 71.24 98.966 280.48 Lacatate 80.199 59.895 27.472 73.667 44.132 70.29 50.013 85.155 56.179 64.61 172.298 133.209 72.363 114.601 127.77 134.176 53.29 99.514 208.27 44.562 98.247 NA 83.018 121.839 71.672 NA 88.389 17.251 120.304 162.041 82.6 97.11 247.64 188.32 152.55 123.54 102.913 NA 171.37 63.66 47.18 52.41 61.51 212.425 49.99 188.48 42.37 62.51 90.09 126.8 77.364 123.04 133.02 47.79 156.93 103.32 80.37 51.88 Alanine 383.673 356.072 399.334 385.052 405.646 434.298 357.49 440.415 381.397 311.723 386.988 392.706 333.001 347.981 432.635 393.753 419.033 428.607 383.098 398.638 385.287 422.021 314.328 375.073 380.41 428.762 345.497 353.356 348.808 416.794 68.74 431.45 395.21 465.32 410.93 399.83 362.082 427.84 420.21 376.5 408.15 371.21 316.97 384.216 389.61 413.54 372.58 373.2 439.15 430.95 359.997 453.24 440.81 350.66 457.72 355.98 251.086 331.75 metabolite_name Citrate cis.Aconitate Isocitrate Ketoglutarate succinate fummarate Malate Oxaloacetate Aspartate Glutamate Lacatate Alanine