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5.26301327419988 0.806045022112033 0.676691033948161 2.56683994577782 0.399477800160397 0.897179888673091 1.81687040811044 0.414757844052915 0.361603115192788 2.97659169076416 1.97254673797083 15.9748622463906 0.475897694328661 1.82475134467154 0.284095614751085 0.565941127834923 1.79629626336893 1.54939564267885 0.962444074999333 0.283508275846959 1.30285932938791 0.624540946529618 0.968140648570623 0.408618857200745 0.989488503777572 0.647328073119933 0.671507443102192 10.0057359033437 1.45312524913297 0.323807854988016 5.56487452572696 0.660514919301648 0.639826118331406 1.12686883807411 17.5789058979558 3.12662070684628 0.345031363822847 1.37120981400091 0.80499404470669 2.51255778469661 0.925277026639747 1.08555394869908 2.65553954067567 0.675642019527955 0.476697587385138 0.506048691292388 3.36834057415952 0.629213991460729 0.357833803042292 0.530749619935811 0.995141731646838 3.55061127293846 0.821791690280691 0.588728029409306 1.88628345299247 1.71830766629278 0.245801730378107 0.445151513330137 1.00159027485464 0.861383995081819 0.505999498831478 2.51303833431021 0.74862475335545 0.394254614439 1.58736324539065 7.86783775032943 0.852435294397104 0.570490322892028 3.14610344852324 3-methyladipate 1 1 1 0 0 1 1 0 1 1 0 1 0 0 1 1 1 0 0 1 1 1 0 1 1 1 0 1 1 0 1 1 1 1 0 1 0 0 1 1 1 1 0 1 1 1 0 1 1 1 1 0 1 0 1 1 1 0 1 1 1 1 1 1 1 1 0 1 1 1 1 0 1 1 1 1 1 1 0 1 1 1 1 1 1 0 1 0 1 1 1 1 1 1 1 1 0 1 0 1 0 0 1 1 0 1 1 1 0 1 1 1 0 1 1 1 0 1 1 1 1 1 1 0 1 1 1 1 1 1 0 1 1 0 1 0 1 0 0 1 1 1 1 1 1 1 1 1 0 1 0 1 1 1 1 1 1 1 1 1 0 1 1 1 0 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 0 0 1 1 1 1 1 1 1 1 0 1 1 1 1 1 1 0 0 1 1 1 0 1 0 1 1 1 1 0 1 0 1 1 1 1 0 0 0 1 0 1 0 1 1 1 0 1 1 0 1 1 0 1 0 1 1 1 1 0 1 1 1 1 1 1 1 1 0 1 1 0 1 1 1 1 1 0 0 0 1 0 0 1 0 1 1 1 1 1 0 1 0 1 1 1 1 1 1 0 0 1 0 1 0 1 1 1 1 1 1 1 1 1 1 1 1 1 1 0 1 1 1 0 1 1 1 0 0 0 0 1 0 1 0 1 0 1 1 1 0 1 1 1 0 0 0 1 0 1 0 1 1 1 0 1 1 1 0 0 0 1 1 1 0 1 1 1 1 1 1 1 0 0 1 1 1 0 1 0 1 0 1 0 0 1 1 1 1 1 1 1 0 1 1 0 0 0 1 1 1 1 1 0 1 0 1 0 1 1 0 1 0 1 0 0 1 1 1 0 0 0 1 1 1 0 0 1 1 1 1 1 1 0 1 1 1 1 1 1 0 1 1 0 0 1 1 1 0 1 0 0 1 1 1 1 1 1 0 1 0 1 1 0 1 0 1 1 1 0 1 1 1 1 0 1 1 1 1 0 1 1 1 1 1 0 1 1 1 0 1 0 0 0 0 0 1 0 0 1 1 1 0 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 0 1 1 1 1 0 1 1 0 1 1 1 0 1 1 1 1 1 1 1 0 1 1 0 0 1 1 0 0 1 0 1 1 1 1 0 1 1 1 1 0 1 0 0 1 1 1 1 1 1 1 0 1 1 0 0 1 1 0 1 0 1 1 1 1 1 1 0 1 1 1 1 1 1 1 1 1 1 1 1 0 1 1 0 0 1 1 1 1 0 1 1 1 0 1 0 1 1 1 0 0 1 1 1 1 0 0 0 1 1 0 0 1 1 1 1 1 0 1 1 1 0 1 1 1 1 0 1 1 1 1 0 1 0 1 1 1 1 0 0 0 0 1 1 1 1 1 0 0 0 1 1 0 1 1 1 0 1 1 1 0 1 1 0 1 0 0 1 0 1 1 1 0 1 1 1 1 0 1 1 1 1 1 1 1 1 0 1 1 1 1 1 0 0 0 0 0 1 0 1 1 1 1 1 1 1 1 1 0 1 1 1 1 1 1 1 0 0 0 0 0 0 1 0 0 1 1 1 1 0 1 1 0 0 1 1 1 1 0 0 1 0 1 1 1 0 1 1 0 1 1 1 0 1 0 1 1 0 1 1 1 0 1 1 1 1 1 0 1 0 1 1 1 0 0 1 1 0 1 1 0 1 1 1 0 1 0 1 0 1 0 1 1 1 1 1 1 0 1 1 1 1 1 1 1 1 0 1 1 0 0 1 1 1 1 0 1 0 1 1 1 1 1 0 1 1 1 1 0 1 0 0 1 1 0 1 0 0 1 1 1 1 1 1 1 0 1 0 1 0 0 0 0 1 1 1 1 1 1 1 1 0 1 1 0 1 0 1 0 1 1 1 1 1 0 0 1 1 1 1 0 0 1 1 1 1 1 1 0 1 1 1 1 1 1 1 1 0 1 1 1 1 1 1 1 0 1 0 1 1 1 1 0 1 1 1 0 1 1 1 0 1 0 1 1 1 1 1 1 0 1 1 1 1 0 1 1 0 1 1 1 1 1 1 1 1 1 0 1 1 1 0 0 1 0 1 1 0 0 0 1 1 1 1 1 0 1 1 0 1 1 1 1 1 1 1 1 1 1 1 0 1 0 1 1 1 0 1 1 1 1 1 1 1 1 1 0 1 1 0 1 1 1 0 1 1 1 1 1 0 0 0 1 0 1 1 0 1 0 0 1 1 1 0 1 1 1 0 0 0 1 1 1 1 0 1 0 0 1 1 1 1 1 1 1 1 1 0 1 1 1 1 1 1 1 1 1 0 1 1 1 1 1 0 0 1 1 1 0 1 1 1 0 0 0 0 1 1 1 0 0 0 1 1 1 1 1 1 1 0 0 1 0 1 1 0 0 0 0 1 1 1 0 0 1 1 1 1 0 0 1 1 0 1 1 0 1 1 1 1 1 0 1 0 0 1 0 N-acetylserine 0.849038624602809 1.10092939552419 0.849701399721151 1.07895835459036 0.747280483876481 0.679458894972231 0.862172185618502 0.756305354111907 1.04637483768745 1.29329035885714 1.14070985108401 0.784736784119325 0.833595423929582 0.840802014674919 1.15242969589261 1.1790620885992 1.01015209951419 1.05501649692125 1.51719684940491 1.27130304089858 0.873009477575443 0.921531593543363 0.506985152470871 1.05924419173691 0.834414774293659 1.38500258138474 0.708156710477266 1.8271578855547 1.26193224236154 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1.15197262033518 0.451282661075821 0.836484237484671 2.67933786024971 0.936759485830554 1.10049926758227 1.91042087805489 1.73318262917605 1.44844134305473 1.31973628284081 0.689766724753619 0.987125958305874 0.664213771287468 1.55842552823236 1.02762279115597 1.56434896823697 1.33019211526579 1.08408461191841 2.438589173542 1.29055543386426 1.43385438703944 2.26276445078543 0.675057764028749 1.50675112092576 1.79878683540677 1.46533111848895 1.29845227556717 1.46783463148062 0.920878394125157 0.997714316794939 0.870546328197342 1.33476139781211 0.815316454846054 1.59467068910968 N-methyltaurine 0 0 0 0 0 0 0 0 1 0 0 0 0 1 0 0 0 0 0 1 1 0 0 0 1 1 1 0 1 0 0 0 1 0 0 0 1 0 1 0 1 0 0 0 1 0 0 0 0 0 1 0 0 1 1 1 0 0 0 1 1 1 1 1 0 0 0 0 1 1 1 1 0 0 1 0 0 0 0 1 0 0 1 0 1 0 0 1 1 0 0 1 0 0 0 1 0 0 0 0 1 0 1 0 0 0 1 0 0 1 1 0 0 0 1 0 0 0 0 0 1 1 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 1 0 1 0 1 0 0 0 0 0 1 1 0 1 0 0 0 0 0 0 0 0 0 1 1 0 0 1 0 0 0 0 1 0 1 1 1 1 0 0 0 0 0 0 0 0 0 0 0 1 0 0 1 1 1 0 0 0 0 0 0 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NA NA NA NA NA NA NA NA NA NA NA NA NA NA 1 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 1.39146167997421 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.943165010339483 NA 0.711178545313703 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.54802900523355 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA metabolite_name CHEM_ID LIB_ID COMP_ID CHRO_LIB_ENTRY_ID SUPER_PATHWAY SUB_PATHWAY PATHWAY_SORTORDER INCHIKEY SMILES CAS CHEMSPIDER HMDB KEGG PUBCHEM PLATFORM miss_pct imputation alpha-ketoglutarate 93 305 528 146398 Energy TCA Cycle 1446 KPGXRSRHYNQIFN-UHFFFAOYSA-N O=C(C(O)=O)CCC(O)=O 328-50-7,22202-68-2,305-72-6 50 HMDB0000208 C00026 51 Polar 0 KNN 3-hydroxyisobutyrate 111 305 1549 147711 Amino Acid Leucine, Isoleucine and Valine Metabolism 428 DBXBTMSZEOQQDU-UHFFFAOYSA-N CC(C(O)=O)CO 2068-83-9 10140307 HMDB0000023,HMDB0000336 C01188,C06001 11966314 Polar 0.0325704225352113 KNN 3-hydroxy-3-methylglutarate 112 305 531 146400 Lipid Mevalonate Metabolism 3176 NPOAOTPXWNWTSH-UHFFFAOYSA-N CC(CC(O)=O)(CC(O)=O)O 503-49-1 4573695 HMDB0000355 C03761 1662,5459993 Polar 0.0132042253521127 KNN succinate 252 305 1437 147106 Energy TCA Cycle 1449 KDYFGRWQOYBRFD-UHFFFAOYSA-N OC(CCC(O)=O)=O 110-15-6 1078 HMDB0000254 C00042 1110 Polar 0.00176056338028169 KNN 3-hydroxybutyrate (BHBA) 254 305 542 145710 Lipid Ketone Bodies 1939 WHBMMWSBFZVSSR-UHFFFAOYSA-N CC(O)CC(O)=O 625-72-9 428 HMDB0000442,HMDB0000357,HMDB0000011 C03197,C01089 94318,441,92135 Polar 0.00616197183098592 KNN fumarate 330 305 1643 146876 Energy TCA Cycle 1450 VZCYOOQTPOCHFL-OWOJBTEDSA-N OC(/C=C/C(O)=O)=O 100-17-8 10197150 HMDB0000134 C00122 444972 Polar 0.0132042253521127 KNN gluconate 338 305 587 147098 Xenobiotics Food Component/Plant 4806 RGHNJXZEOKUKBD-SQOUGZDYSA-N OC([C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)=O 527-07-1 10240 HMDB0000625 C00257 10690,3085666 Polar 0.000880281690140845 KNN glutarate (C5-DC) 339 305 396 146390 Lipid Fatty Acid, Dicarboxylate 1660 JFCQEDHGNNZCLN-UHFFFAOYSA-N OC(CCCC(O)=O)=O 110-94-1 3618533 HMDB0000661 C00489 743,4418048 Polar 0.0492957746478873 KNN guanidinoacetate 344 305 43802 147630 Amino Acid Creatine Metabolism 527 BPMFZUMJYQTVII-UHFFFAOYSA-N NC(NCC(O)=O)=N 352-97-6 743 HMDB0000128 C00581 763 Polar 0.000880281690140845 KNN myo-inositol 363 305 1124 145716 Lipid Inositol Metabolism 2202 CDAISMWEOUEBRE-GPIVLXJGSA-N O[C@@H]1[C@@H](O)[C@H](O)[C@H](O)[C@H](O)[C@H]1O 87-89-8 10239179 HMDB0000211 C00137 892 Polar 0 KNN 2-aminoadipate 381 305 6146 147948 Amino Acid Lysine Metabolism 123 OYIFNHCXNCRBQI-UHFFFAOYSA-N OC(CCCC(N)C(O)=O)=O 1118-90-7,542-32-5 456 HMDB0000510 C00956 92136 Polar 0.198943661971831 KNN lactose 393 305 567 147468 Carbohydrate Disaccharides and Oligosaccharides 1305 GUBGYTABKSRVRQ-DCSYEGIMSA-N O[C@H]1[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](O)O[C@@H]2CO)O[C@H](CO)[C@H](O)[C@@H]1O 5965-66-2 5904 HMDB0041627 C01970 6134 Polar 0.492077464788732 Present/Absent methylmalonate (MMA) 418 305 1496 145730 Lipid Fatty Acid Metabolism (also BCAA Metabolism) 1775 ZIYVHBGGAOATLY-UHFFFAOYSA-N O=C(C(C(O)=O)C)O 516-05-2 473 HMDB0000202 C02170 487 Polar 0.051056338028169 KNN orotate 445 305 1505 146440 Nucleotide Pyrimidine Metabolism, Orotate containing 4208 PXQPEWDEAKTCGB-UHFFFAOYSA-N O=C(C1=CC(O)=NC(O)=N1)O 50887-69-9 942 HMDB0000226 C00295 967 Polar 0 KNN salicylate 501 305 1515 164364 Xenobiotics Drug - Topical Agents 5961 YGSDEFSMJLZEOE-UHFFFAOYSA-N OC1=C(C(O)=O)C=CC=C1 69-72-7 331 HMDB0001895 C00805 338 Polar 0 KNN glucose 572 305 48152 151982 Carbohydrate Glycolysis, Gluconeogenesis, and Pyruvate Metabolism 1223 WQZGKKKJIJFFOK-DVKNGEFBSA-N O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O 50-99-7 71358 HMDB0000122 C00031 5793 Polar 0 KNN alpha-ketobutyrate 796 305 4968 152126 Amino Acid Methionine, Cysteine, SAM and Taurine Metabolism 454 TYEYBOSBBBHJIV-UHFFFAOYSA-N OC(C(CC)=O)=O 600-18-0 2829426 HMDB0000005 C00109 58 Polar 0.0167253521126761 KNN mannose 803 305 48153 152039 Carbohydrate Fructose, Mannose and Galactose Metabolism 1353 WQZGKKKJIJFFOK-DXQLJALPSA-N O[C@@H]1C(CO)O[C@@H](O)[C@@H](O)[C@H]1O 3458-28-4 141983 HMDB0000169 C00159,C02209,C00936 82308,439680,185698,18950 Polar 0 KNN uracil 825 305 605 146422 Nucleotide Pyrimidine Metabolism, Uracil containing 4221 ISAKRJDGNUQOIC-UHFFFAOYSA-N O=C(NC=C1)NC1=O 66-22-8 1141 HMDB0000300 C00106 1174 Polar 0.0801056338028169 KNN xylose 826 305 15581 146484 Carbohydrate Pentose Metabolism 1267 PYMYPHUHKUWMLA-VPENINKCSA-N O=C[C@@H]([C@H]([C@@H](CO)O)O)O 609-06-3 85957 HMDB0000098 C00181 135191 Polar 0.147887323943662 KNN arabinose 828 305 575 146408 Carbohydrate Pentose Metabolism 1269 SRBFZHDQGSBBOR-SQOUGZDYSA-N O[C@@H]1CO[C@@H](O)[C@@H](O)[C@@H]1O 28697-53-2 59687 HMDB0029942 C00216 66308 Polar 0.0686619718309859 KNN fructose 878 305 48195 153126 Carbohydrate Fructose, Mannose and Galactose Metabolism 1347 RFSUNEUAIZKAJO-ARQDHWQXSA-N OC[C@@]1(O)O[C@H](CO)[C@@H](O)[C@@H]1O 57-48-7 5764 HMDB0000660 C00095 2723872 Polar 0.00176056338028169 KNN maltose 913 305 15586 146486 Carbohydrate Glycogen Metabolism 1300 GUBGYTABKSRVRQ-ASMJPISFSA-N O[C@@H]1[C@H]([C@H](O[C@@H]([C@H]1O)CO)O[C@H]2[C@@H]([C@H]([C@H](O[C@@H]2CO)O)O)O)O 6363-53-7 388469 HMDB0000163 C00208 10991489 Polar 0.171654929577465 KNN dihydroorotate 923 305 601 145712 Nucleotide Pyrimidine Metabolism, Orotate containing 4207 UFIVEPVSAGBUSI-UHFFFAOYSA-N O=C(C(NC1=O)CC(N1)=O)O 155-54-4 628 HMDB03349 C00337 648 Polar 0 KNN sucrose 935 305 1519 147116 Carbohydrate Disaccharides and Oligosaccharides 1326 CZMRCDWAGMRECN-UGDNZRGBSA-N OC[C@]1(O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O)[C@H]([C@@H]([C@@H](CO)O1)O)O 57-50-1 5768 HMDB0000258 C00089 5988 Polar 0.0105633802816901 KNN allantoin 1002 305 1107 146424 Nucleotide Purine Metabolism, (Hypo)Xanthine/Inosine containing 4134 POJWUDADGALRAB-UHFFFAOYSA-N O=C(N1)C(NC(N)=O)NC1=O 97-59-6 199 HMDB0000462 C02348,C01551,C02350 439714,204,439713 Polar 0 KNN xanthine 1004 305 3147 147146 Nucleotide Purine Metabolism, (Hypo)Xanthine/Inosine containing 4122 LRFVTYWOQMYALW-UHFFFAOYSA-N O=C(N1)C(N=CN2)=C2NC1=O 69-89-6 1151 HMDB0000292 C00385 1188 Polar 0.000880281690140845 KNN glycerate 1052 305 1572 146444 Carbohydrate Glycolysis, Gluconeogenesis, and Pyruvate Metabolism 1243 RBNPOMFGQQGHHO-UHFFFAOYSA-N O=C(O)C(O)CO 600-19-1 732 HMDB0000139,HMDB0006372 C00258 439194,752 Polar 0 KNN N-acetylalanine 1110 305 1585 147717 Amino Acid Alanine and Aspartate Metabolism 31 KTHDTJVBEPMMGL-VKHMYHEASA-N O=C(O)[C@@H](NC(C)=O)C 97-69-8 79449 HMDB0000766 C02847 88064 Polar 0.00616197183098592 KNN methylsuccinate 2051 305 15745 146490 Amino Acid Leucine, Isoleucine and Valine Metabolism 410 WXUAQHNMJWJLTG-UHFFFAOYSA-N CC(C(O)=O)CC(O)=O 498-21-5 9922 HMDB0001844 NA 10349 Polar 0.0264084507042254 KNN ethylmalonate 2054 305 15765 147158 Amino Acid Leucine, Isoleucine and Valine Metabolism 407 UKFXDFUAPNAMPJ-UHFFFAOYSA-N CCC(C(O)=O)C(O)=O 601-75-2 11263 HMDB0000622 NA 11756 Polar 0 KNN suberate (C8-DC) 100000016 305 15730 145770 Lipid Fatty Acid, Dicarboxylate 1677 TYFQFVWCELRYAO-UHFFFAOYSA-N OC(CCCCCCC(O)=O)=O 505-48-6 10025 HMDB0000893 C08278 10457 Polar 0.0378521126760563 KNN pimelate (C7-DC) 100000101 305 15704 147156 Lipid Fatty Acid, Dicarboxylate 1674 WLJVNTCWHIRURA-UHFFFAOYSA-N OC(CCCCCC(O)=O)=O 111-16-0 376 HMDB0000857 C02656 385 Polar 0.470950704225352 Present/Absent glucuronate 100000257 305 15443 146478 Carbohydrate Aminosugar Metabolism 1407 AEMOLEFTQBMNLQ-QIUUJYRFSA-N O[C@@H]1O[C@H]([C@](O)=O)[C@@H](O)[C@H](O)[C@H]1O 207300-70-7 58552 HMDB0000127 C16245 441478,23677976,94715,65041,444791 Polar 0.00616197183098592 KNN allo-threonine 100000272 305 15142 145758 Amino Acid Glycine, Serine and Threonine Metabolism 19 AYFVYJQAPQTCCC-HRFVKAFMSA-N O=C(O)[C@@H](N)[C@H](C)O 28954-12-3 89699 HMDB0004041 C05519 99289 Polar 0.244718309859155 Present/Absent 2-isopropylmalate 100000409 305 15667 152132 Xenobiotics Food Component/Plant 4781 BITYXLXUCSKTJS-UHFFFAOYSA-N OC(CC(O)=O)(C(C)C)C(O)=O 3237-44-3 76 HMDB0000402 C02504 77 Polar 0.0774647887323944 KNN quinate 100000442 305 18335 146498 Xenobiotics Food Component/Plant 4906 AAWZDTNXLSGCEK-WYWMIBKRSA-N O[C@@]1([C@](O)(C[C@@](C(O)=O)(C[C@]1(O)[H])O)[H])[H] 77-95-2 10246715 HMDB0003072 C00296 6508 Polar 0.00792253521126761 KNN gentisate 100000447 305 18280 152144 Amino Acid Tyrosine Metabolism 219 WXTMDXOMEHJXQO-UHFFFAOYSA-N O=C(O)C1=CC(O)=CC=C1O 490-79-9 3350 HMDB0000152 C00628 3469 Polar 0.0757042253521127 KNN maleate 100000707 305 20676 147767 Lipid Fatty Acid, Dicarboxylate 1672 VZCYOOQTPOCHFL-UHFFFAOYSA-N O=C(C=CC(O)=O)O 110-16-7 392248 HMDB0000176 C01384 444266 Polar 0 KNN erythritol 100000846 305 20699 146508 Xenobiotics Food Component/Plant 4896 UNXHWFMMPAWVPI-UHFFFAOYSA-N OCC(O)C(CO)O 149-32-6 13835932 HMDB0002994 C00503 222285 Polar 0.00176056338028169 KNN ribonate 100001007 305 27731 147186 Carbohydrate Pentose Metabolism 1263 QXKAIJAYHKCRRA-BXXZVTAOSA-N OC([C@H](O)[C@H](O)[C@H](O)CO)=O 5336-08-3 4574162 HMDB0000867 C01685 5460677 Polar 0.00176056338028169 KNN threonate 100001022 305 27738 146524 Cofactors and Vitamins Ascorbate and Aldarate Metabolism 4354 JPIJQSOTBSSVTP-UHFFFAOYSA-N O=C(O)C(O)([H])C([H])(O)CO 70753-61-6 133224 HMDB0062620,HMDB0000943 C01620 151152,5460407 Polar 0 KNN galactonate 100001026 305 27719 152158 Carbohydrate Fructose, Mannose and Galactose Metabolism 1373 RGHNJXZEOKUKBD-MGCNEYSASA-N O[C@H]([C@H]([C@H]([C@@H](CO)O)O)O)C(O)=O 299-28-5 114198 HMDB0000565 C00880,C15930 12310779,128869 Polar 0.0748239436619718 KNN sebacate (C10-DC) 100001211 305 32398 165423 Lipid Fatty Acid, Dicarboxylate 1682 CXMXRPHRNRROMY-UHFFFAOYSA-N OC(CCCCCCCCC(O)=O)=O 111-20-6 5004 HMDB0000792 C08277 5192 Polar 0.0492957746478873 KNN N-acetylglutamine 100001253 305 33943 146952 Amino Acid Glutamate Metabolism 48 KSMRODHGGIIXDV-YFKPBYRVSA-N OC([C@H](CCC(N)=O)NC(C)=O)=O 2490-97-3 158492 HMDB0006029 C02716 182230 Polar 0 KNN alpha-hydroxyisovalerate 100001300 305 46537 146562 Amino Acid Leucine, Isoleucine and Valine Metabolism 424 NGEWQZIDQIYUNV-UHFFFAOYSA-N OC(C(O)=O)C(C)C 600-37-3 90190 HMDB0000407 NA 99823 Polar 0 KNN erythronate* 100001320 305 42420 148204 Carbohydrate Aminosugar Metabolism 1432 JPIJQSOTBSSVTP-PWNYCUMCSA-N OC[C@@H](O)[C@@H](O)C(O)=O 88759-55-1 2061231 HMDB0000613 NA 2781043 Polar 0 KNN 5-acetylamino-6-formylamino-3-methyluracil 100001402 305 34401 165248 Xenobiotics Xanthine Metabolism 4605 RDZNZFGKEVDNPK-UHFFFAOYSA-N O=C(NC(NC=O)=C1NC(C)=O)N(C)C1=O 85438-96-6 97287 HMDB0011105 C16365 108214 Polar 0.0730633802816901 KNN 5-acetylamino-6-amino-3-methyluracil 100001403 305 34424 165245 Xenobiotics Xanthine Metabolism 4604 POQOTWQIYYNXAT-UHFFFAOYSA-N O=C(NC(N)=C1NC(C)=O)N(C)C1=O 1196153-01-1 79659 HMDB0004400 C16366 88299 Polar 0.0246478873239437 KNN orotidine 100001416 305 35172 147813 Nucleotide Pyrimidine Metabolism, Orotate containing 4210 FKCRAVPPBFWEJD-XVFCMESISA-N O=C(C=C(C(O)=O)N1[C@H]2[C@H](O)[C@H](O)[C@@H](CO)O2)NC1=O 314-50-1 83729 HMDB0000788 NA 92751 Polar 0 KNN gulonate* 100001586 305 46957 148205 Cofactors and Vitamins Ascorbate and Aldarate Metabolism 4358 RGHNJXZEOKUKBD-NRXMZTRTSA-N OC([C@H](O)[C@H](O)[C@H](O)[C@@H](O)CO)=O 20246-53-1 7969943 HMDB0003290 C00800 152304 Polar 0.0308098591549296 KNN glycerophosphoglycerol 100001619 305 48857 160476 Lipid Glycerolipid Metabolism 2848 LLCSXHMJULHSJN-UHFFFAOYSA-N OC(CO)COP(O)(OCC(CO)O)=O NA 388990 HMDB0240316 C03274 54575349 Polar 0.242077464788732 Present/Absent N2-acetyllysine 100001721 305 36751 145848 Amino Acid Lysine Metabolism 106 VEYYWZRYIYDQJM-ZETCQYMHSA-N OC([C@H](CCCCN)NC(C)=O)=O 1946-82-3 83869 HMDB0000446 C12989 92907 Polar 0.447183098591549 Present/Absent mannitol/sorbitol 100001740 305 46142 146560 Carbohydrate Fructose, Mannose and Galactose Metabolism 1352 FBPFZTCFMRRESA-UHFFFAOYSA-N OCC(O)C(O)C(O)C(O)CO NA 440 HMDB0000247,HMDB0000765 C00392,C00794 5780,6251 Polar 0 KNN 3-methyladipate 100001765 305 36749 146966 Lipid Fatty Acid, Dicarboxylate 1670 SYEOWUNSTUDKGM-UHFFFAOYSA-N O=C(O)CC(C)CCC(O)=O 3058-01-3 11789 HMDB0000555 NA 12292 Polar 0.29137323943662 Present/Absent N-acetylserine 100001851 305 37076 147598 Amino Acid Glycine, Serine and Threonine Metabolism 11 JJIHLJJYMXLCOY-BYPYZUCNSA-N OC[C@@H](C(O)=O)NC(C)=O 97-14-3 58744 HMDB0002931 NA 65249 Polar 0 KNN chiro-inositol 100001859 305 37112 145854 Lipid Inositol Metabolism 2203 CDAISMWEOUEBRE-LKPKBOIGSA-N O[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@@H](O)[C@@H]1O 643-12-9 10254647 HMDB0240209 C19891 NA Polar 0.444542253521127 Present/Absent 1-stearoyl-2-oleoyl-GPG (18:0/18:1) 100001866 305 52623 165367 Lipid Phosphatidylglycerol (PG) 2528 ZEFGRNLJASLRBZ-GXFQOPFSSA-N O=P(OCC(O)CO)(O)OC[C@H](OC(CCCCCCC/C=CCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O 322647-48-3 NA HMDB0010604 NA 24779551 Polar 0.0440140845070423 KNN alpha-ketoglutaramate* 100002397 305 62101 218946 Amino Acid Glutamate Metabolism 46 COJBGNAUUSNXHX-UHFFFAOYSA-N NC(CCC(C(O)=O)=O)=O 18465-19-5 NA HMDB0001552 C00940 48 Polar 0 KNN 2,3-dihydroxyisovalerate 100002417 305 38276 152194 Xenobiotics Food Component/Plant 4773 JTEYKUFKXGDTEU-UHFFFAOYSA-N OC(C(O)C(C)(O)C)=O 1756-18-9 657 HMDB0012141 C04039 677 Polar 0.00176056338028169 KNN 3-methylglutaconate 100002458 305 38667 145864 Amino Acid Leucine, Isoleucine and Valine Metabolism 367 WKRBKYFIJPGYQC-DUXPYHPUSA-N OC(C/C(C)=C/C(O)=O)=O 5746-90-7 1267861 HMDB0000522 NA 1551553 Polar 0.000880281690140845 KNN oxypurinol 100002489 305 41726 147004 Xenobiotics Drug - Metabolic 5804 HXNFUBHNUDHIGC-UHFFFAOYSA-N O=C(N1)NC2=C(C=NN2)C1=O 2465-59-0 4483 HMDB0000786 D02365 135398752 Polar 0.984154929577465 Exclude hydantoin-5-propionate 100002514 305 40473 152212 Amino Acid Histidine Metabolism 77 VWFWNXQAMGDPGG-UHFFFAOYSA-N O=C1NC(C(CCC(O)=O)N1)=O 5624-26-0 761 HMDB0001212 C05565 782 Polar 0.0132042253521127 KNN 4-hydroxy-2-oxoglutaric acid 100002537 305 40062 207371 Lipid Fatty Acid, Dicarboxylate 1665 WXSKVKPSMAHCSG-UHFFFAOYSA-N OC(C(O)=O)CC(C(O)=O)=O 1187-99-1 579 HMDB0002070 C01127 599 Polar 0.0633802816901408 KNN mannonate* 100003695 305 62864 220652 Xenobiotics Food Component/Plant 4960 RGHNJXZEOKUKBD-MBMOQRBOSA-N O=C([C@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O)O 642-99-9 2496757 NA NA 3246006 Polar 0 KNN succinimide 100003696 305 41888 152218 Xenobiotics Chemical 6201 KZNICNPSHKQLFF-UHFFFAOYSA-N O=C1NC(CC1)=O 123-56-8 10955 NA C07273 11439 Polar 0.00440140845070423 KNN N-methyltaurine 100004056 305 42989 180877 Amino Acid Methionine, Cysteine, SAM and Taurine Metabolism 472 SUZRRICLUFMAQD-UHFFFAOYSA-N O=S(O)(CCNC)=O 107-68-6 7594 NA NA 7882 Polar 0.684859154929577 Present/Absent 3-hydroxyadipate 100004396 305 62069 218878 Lipid Fatty Acid, Dicarboxylate 1669 YVOMYDHIQVMMTA-UHFFFAOYSA-N OC(CC(O)=O)CCC(O)=O NA 133894 HMDB0000345 NA 151913 Polar 0.161091549295775 KNN 2-keto-3-deoxy-gluconate 100005946 305 48141 160468 Xenobiotics Food Component/Plant 5131 WPAMZTWLKIDIOP-WVZVXSGGSA-N OC[C@@H](O)[C@@H](O)CC(C(O)=O)=O 17510-99-5 141630 HMDB0001353 C00204 161227 Polar 0 KNN arabonate/xylonate 100006115 305 48255 153226 Carbohydrate Pentose Metabolism 1283 QXKAIJAYHKCRRA-JJYYJPOSSA-N OC([C@H]([C@@H]([C@@H](CO)O)O)O)=O NA NA HMDB0000539 C00502,C05411 122045,6602431 Polar 0 KNN arabitol/xylitol 100006430 305 48885 160479 Carbohydrate Pentose Metabolism 1277 HEBKCHPVOIAQTA-IMJSIDKUSA-N OC[C@@H](C([C@H](CO)O)O)O NA NA HMDB0001851,HMDB0000568,HMDB0002917 C00379,C00542,C01904 94154,6912 Polar 0 KNN citraconate/glutaconate 100006438 305 47076 148336 Energy TCA Cycle 1463 HNEGQIOMVPPMNR-IHWYPQMZSA-N C/C(C(O)=O)=C/C(O)=O NA NA HMDB0000634,HMDB0000620 C02226,C02214 5280498,643798 Polar 0 KNN 2-hydroxybutyrate/2-hydroxyisobutyrate 100008928 305 52281 164309 Amino Acid Glutathione Metabolism 582 AFENDNXGAFYKQO-UHFFFAOYSA-N CCC(O)C(O)=O NA NA HMDB0000729,HMDB00008 C21297,C05984 440864,4277439 Polar 0 KNN 1-linoleoyl-GPA (18:2)* 100009082 305 52690 165463 Lipid Lysophospholipid 2588 ZQTAMPRZFOOEEP-KKFOGOCZSA-N O=C(CCCCCCC/C=CC/C=CCCCCC)OC[C@]([H])(COP(O)(O)=O)O NA 24766514 HMDB0007856 NA NA Polar 0.392605633802817 Present/Absent isocitric lactone 100009239 305 54724 207379 Energy TCA Cycle 1445 UKZDIMBDWHZXOK-UHFFFAOYSA-N OC(C(C1)C(C(O)=O)OC1=O)=O 4702-32-3 88729 NA NA 98259 Polar 0.0580985915492958 KNN caffeic acid sulfate 100009337 305 53254 179431 Xenobiotics Food Component/Plant 5205 SNVAIAITQIIEMQ-DUXPYHPUSA-N OS(OC1=CC=C(C=C1O)/C=C/C(O)=O)(=O)=O NA 30777608 HMDB0041708 NA 21668705 Polar 0.0924295774647887 KNN perfluorooctanesulfonate (PFOS) 100010955 305 57564 211466 Xenobiotics Chemical 6192 YFSUTJLHUFNCNZ-UHFFFAOYSA-N O=S(C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)(O)=O 1763-23-1 67068 HMDB0059586 C18142 74483 Polar 0.00264084507042254 KNN dexlansoprazole 100015794 305 57668 212835 Xenobiotics Drug - Gastrointestinal 5751 MJIHNNLFOKEZEW-RUZDIDTESA-N CC1=C(OCC(F)(F)F)C=CN=C1C[S@](C2=NC3=CC=CC=C3N2)=O 138530-94-6 7852369 NA D08903 9578005 Polar 0.985915492957746 Exclude lyxonate 100019968 305 61858 218556 Carbohydrate Pentose Metabolism 1290 QXKAIJAYHKCRRA-PZGQECOJSA-N OC[C@H](O)[C@@H](O)[C@@H](O)C(O)=O NA NA HMDB0060255 NA NA Polar 0.0202464788732394 KNN heptenedioate (C7:1-DC)* 100019981 305 61866 218583 Lipid Fatty Acid, Dicarboxylate 1675 OXQWBLJQOBXJPM-DUXPYHPUSA-N OC(CCC/C=C/C(O)=O)=O NA NA NA NA NA Polar 0.0404929577464789 KNN carboxyibuprofen glucuronide* 100020212 305 62067 218874 Xenobiotics Drug - Analgesics, Anesthetics 5400 FLVLKWAQHDRIPH-UHFFFAOYSA-N CC(C(OC1OC(C(O)=O)C(O)C(O)C1O)=O)C2=CC=C(CC(C)C(O)=O)C=C2 NA NA HMDB60564 NA 135390721 Polar 0.751760563380282 Present/Absent fibrinopeptide B (1-12)** 100020910 305 62814 220447 Peptide Fibrinogen Cleavage Peptide 1179 BQQBOORXDTXWLE-UHFFFAOYSA-N OC(C(CO)NC(C(CC1=CC=CC=C1)NC(C(CC2=CC=CC=C2)NC(CNC(C(CCC(O)=O)NC(C(CCC(O)=O)NC(C(CC(N)=O)NC(C(CC(O)=O)NC(C(CC(N)=O)NC(C(C(C)C)NC(CNC(C(CC3)NC3=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O NA NA NA NA 16132131 Polar 0.983274647887324 Exclude fibrinopeptide B (1-11)** 100020912 305 62815 220449 Peptide Fibrinogen Cleavage Peptide 1178 YXFOTICOZNPKPN-UHFFFAOYSA-N OC(C(CC1=CC=CC=C1)NC(C(CC2=CC=CC=C2)NC(CNC(C(CCC(O)=O)NC(C(CCC(O)=O)NC(C(CC(N)=O)NC(C(CC(O)=O)NC(C(CC(N)=O)NC(C(C(C)C)NC(CNC(C(CC3)NC3=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O NA NA NA NA 16132131 Polar 0.98943661971831 Exclude