metabolite_name SGBS_ctrl_d0_1 SGBS_ctrl_d0_2 SGBS_ctrl_d0_3 SGBS_ctrl_d0_4 SGBS_ctrl_d0_5 SGBS_ctrl_d0_6 SGBS_ctrl_d3_1 SGBS_ctrl_d3_2 SGBS_ctrl_d3_3 SGBS_ctrl_d3_4 SGBS_ctrl_d3_5 SGBS_ctrl_d3_6 SGBS_ctrl_d6_1 SGBS_ctrl_d6_2 SGBS_ctrl_d6_3 SGBS_ctrl_d6_4 SGBS_ctrl_d6_5 SGBS_ctrl_d6_6 SGBS_ctrl_d9_1 SGBS_ctrl_d9_2 SGBS_ctrl_d9_3 SGBS_ctrl_d9_4 SGBS_ctrl_d9_5 SGBS_ctrl_d9_6 SGBS_ctrl_d12_1 SGBS_ctrl_d12_2 SGBS_ctrl_d12_3 SGBS_ctrl_d12_4 SGBS_ctrl_d12_5 SGBS_ctrl_d12_6 3T3L1_ctrl_d0_1 3T3L1_ctrl_d0_2 3T3L1_ctrl_d0_3 3T3L1_ctrl_d0_4 3T3L1_ctrl_d0_5 3T3L1_ctrl_d0_6 3T3L1_ctrl_d3_1 3T3L1_ctrl_d3_2 3T3L1_ctrl_d3_3 3T3L1_ctrl_d3_4 3T3L1_ctrl_d3_5 3T3L1_ctrl_d3_6 3T3L1_ctrl_d5_1 3T3L1_ctrl_d5_2 3T3L1_ctrl_d5_3 3T3L1_ctrl_d5_4 3T3L1_ctrl_d5_5 3T3L1_ctrl_d5_6 3T3L1_ctrl_d7_1 3T3L1_ctrl_d7_2 3T3L1_ctrl_d7_3 3T3L1_ctrl_d7_4 3T3L1_ctrl_d7_5 3T3L1_ctrl_d7_6 3T3L1_ctrl_d10_1 3T3L1_ctrl_d10_2 3T3L1_ctrl_d10_3 3T3L1_ctrl_d10_4 3T3L1_ctrl_d10_5 3T3L1_ctrl_d10_6 Glucose-6-phosphate 1.39E+06 1.65E+06 1.56E+06 1.49E+06 1.55E+06 1.41E+06 1.68E+05 1.73E+05 4.23E+05 1.72E+05 2.26E+05 1.80E+05 5.32E+05 5.37E+05 5.24E+05 5.56E+05 5.28E+05 5.62E+05 1.77E+06 1.42E+06 1.82E+06 1.55E+06 1.77E+06 2.49E+06 9.89E+06 1.09E+07 1.12E+07 1.01E+07 9.75E+06 1.86E+06 2.06E+06 2.21E+06 1.65E+06 2.02E+06 2.05E+06 5.78E+06 7.50E+06 6.48E+06 6.61E+06 6.63E+06 6.07E+06 2.16E+07 1.87E+07 1.99E+07 1.96E+07 2.02E+07 2.05E+07 2.68E+07 2.48E+07 2.51E+07 2.75E+07 2.60E+07 2.88E+07 2.48E+07 2.79E+07 2.41E+07 2.99E+07 2.84E+07 Citrate 3.87E+07 3.57E+07 4.22E+07 4.14E+07 4.42E+07 4.18E+07 1.91E+07 2.19E+07 6.03E+07 1.63E+07 1.88E+07 2.29E+07 7.64E+06 1.09E+07 7.91E+06 8.63E+06 7.55E+06 9.14E+06 1.09E+07 8.61E+06 1.39E+07 7.31E+06 9.20E+06 1.15E+07 4.56E+06 4.95E+06 5.00E+06 4.75E+06 5.62E+06 6.38E+06 3.76E+07 4.26E+07 3.93E+07 3.31E+07 3.69E+07 3.84E+07 3.42E+08 3.74E+08 3.39E+08 3.41E+08 3.58E+08 3.10E+08 5.40E+08 4.88E+08 5.03E+08 4.90E+08 5.20E+08 5.22E+08 5.48E+08 5.42E+08 5.29E+08 5.41E+08 5.56E+08 6.13E+08 4.86E+08 4.83E+08 4.81E+08 4.64E+08 4.43E+08 5.09E+08 a-Ketoglutarate 2.84E+06 3.16E+06 3.57E+06 3.60E+06 3.44E+06 3.60E+06 5.53E+05 7.31E+05 7.02E+05 6.81E+05 7.06E+05 6.72E+05 1.29E+06 1.39E+06 1.42E+06 1.51E+06 1.39E+06 1.59E+06 4.95E+05 4.56E+05 4.86E+05 4.70E+05 4.97E+05 5.02E+05 4.12E+05 4.55E+05 4.21E+05 6.70E+05 4.50E+05 5.41E+05 3.53E+06 3.66E+06 3.67E+06 3.35E+06 3.36E+06 4.21E+06 2.16E+07 2.27E+07 2.01E+07 2.24E+07 1.94E+07 1.73E+07 3.89E+07 2.93E+07 3.62E+07 3.34E+07 2.89E+07 3.05E+07 3.09E+07 3.32E+07 3.23E+07 4.00E+07 3.22E+07 4.37E+07 1.62E+07 2.08E+07 1.57E+07 2.24E+07 1.63E+07 2.41E+07 Succinate 5.13E+06 4.32E+06 4.84E+06 4.56E+06 7.26E+06 4.29E+06 8.24E+05 7.70E+05 9.12E+05 8.39E+05 7.91E+05 7.38E+05 1.10E+06 1.30E+06 1.09E+06 1.06E+06 1.09E+06 1.11E+06 5.72E+05 7.18E+05 7.74E+05 6.21E+05 9.17E+05 7.24E+05 6.02E+05 5.74E+05 1.06E+06 6.73E+05 4.88E+05 5.58E+05 1.04E+07 1.41E+07 2.22E+07 9.19E+06 1.10E+07 1.42E+07 4.41E+07 5.65E+07 5.09E+07 4.51E+07 4.46E+07 4.76E+07 7.24E+07 6.08E+07 6.56E+07 6.77E+07 6.52E+07 6.68E+07 1.09E+08 1.09E+08 9.99E+07 1.15E+08 1.11E+08 1.19E+08 2.55E+08 2.24E+08 2.56E+08 2.30E+08 2.81E+08 2.48E+08 Phosphoenolpyruvate 4.47E+05 5.41E+05 5.11E+05 5.51E+05 5.25E+05 5.46E+05 1.84E+05 1.98E+05 2.01E+05 2.06E+05 1.96E+05 2.15E+05 8.28E+05 9.84E+05 8.68E+05 1.00E+06 8.07E+05 8.81E+05 1.88E+06 1.65E+06 1.81E+06 1.54E+06 1.51E+06 1.98E+06 1.11E+06 1.60E+06 1.38E+06 4.89E+05 1.49E+06 1.32E+06 7.04E+05 7.47E+05 7.48E+05 7.31E+05 6.70E+05 7.92E+05 2.47E+06 2.60E+06 1.91E+06 1.87E+06 2.24E+06 1.64E+06 4.54E+06 3.17E+06 5.09E+06 5.12E+06 5.23E+06 6.11E+06 3.00E+06 5.08E+06 2.16E+06 3.30E+06 3.38E+06 4.07E+06 4.52E+06 2.29E+06 2.34E+06 1.24E+06 2.28E+06 2.52E+06 Pyruvate 2.16E+05 2.37E+05 2.41E+05 2.42E+05 2.70E+05 2.31E+05 5.51E+05 7.73E+05 2.06E+06 5.57E+05 6.42E+05 7.80E+05 1.82E+05 1.67E+05 1.82E+05 1.97E+05 2.16E+05 2.46E+05 3.98E+05 3.79E+05 4.41E+05 3.52E+05 3.80E+05 4.38E+05 5.22E+05 5.40E+05 5.43E+05 2.03E+05 5.31E+05 4.92E+05 1.16E+06 1.02E+06 1.80E+06 1.03E+06 1.09E+06 1.61E+06 1.35E+06 1.93E+06 1.20E+06 1.98E+06 1.17E+06 1.66E+06 7.55E+06 4.72E+06 5.40E+06 6.71E+06 5.45E+06 6.45E+06 2.58E+06 3.98E+06 3.38E+06 4.74E+06 3.74E+06 5.86E+06 1.53E+06 1.88E+06 1.43E+06 1.98E+06 1.62E+06 2.50E+06 Fructose-6-phosphate 1.99E+05 2.12E+05 1.87E+05 2.44E+05 2.87E+05 2.12E+05 7.16E+03 1.16E+04 3.77E+04 7.23E+03 1.34E+04 8.43E+03 9.51E+04 8.72E+04 7.90E+04 6.80E+04 7.16E+04 9.08E+04 3.77E+05 1.74E+05 3.78E+05 2.65E+05 3.19E+05 5.18E+05 1.91E+06 2.18E+06 2.29E+06 1.49E+05 1.97E+06 1.94E+06 6.29E+05 6.48E+05 6.31E+05 4.01E+05 6.38E+05 6.96E+05 2.42E+06 3.51E+06 3.08E+06 2.42E+06 2.66E+06 2.12E+06 7.31E+06 7.71E+06 1.02E+07 8.01E+06 8.49E+06 7.18E+06 6.78E+06 7.14E+06 8.81E+06 8.91E+06 9.91E+06 7.77E+06 1.07E+07 7.65E+06 9.02E+06 5.89E+06 7.92E+06 7.95E+06 Glyceraldehyde-3-phosphate 3.62E+04 3.65E+04 4.59E+04 5.18E+04 5.42E+04 7.12E+03 8.16E+03 8.99E+03 1.99E+04 6.94E+03 8.95E+03 7.37E+03 1.01E+05 1.05E+05 9.83E+04 1.09E+05 7.91E+04 1.07E+05 1.46E+05 2.11E+05 1.66E+05 1.58E+05 1.57E+05 1.84E+05 2.40E+05 4.00E+05 2.55E+05 9.63E+04 3.30E+05 2.97E+05 3.11E+04 3.15E+04 2.19E+04 2.12E+04 2.75E+04 3.53E+04 2.86E+05 3.45E+05 3.08E+05 3.40E+05 3.04E+05 3.04E+05 6.59E+05 5.09E+05 5.35E+05 6.15E+05 5.27E+05 5.89E+05 3.16E+05 3.50E+05 3.58E+05 4.66E+05 3.34E+05 4.58E+05 8.77E+05 3.05E+05 2.79E+05 3.36E+05 2.14E+05 2.58E+05 Fumarate 2.35E+05 2.71E+05 2.64E+05 2.45E+05 2.38E+05 2.36E+05 9.95E+04 1.06E+05 1.22E+05 1.04E+05 1.09E+05 1.04E+05 7.10E+04 7.76E+04 7.23E+04 7.67E+04 7.23E+04 7.60E+04 1.10E+05 1.06E+05 1.05E+05 1.04E+05 9.80E+04 1.13E+05 8.23E+05 1.29E+06 1.05E+06 1.07E+05 9.56E+05 9.63E+05 2.38E+05 2.29E+05 1.89E+05 2.03E+05 2.24E+05 2.72E+05 3.16E+06 3.43E+06 3.03E+06 3.14E+06 3.16E+06 2.84E+06 5.63E+06 5.00E+06 5.32E+06 5.18E+06 5.18E+06 5.63E+06 5.25E+06 4.83E+06 4.89E+06 5.74E+06 5.28E+06 5.67E+06 2.75E+06 2.46E+06 2.73E+06 2.63E+06 2.99E+06 2.74E+06 Oxaloacetate 5.68E+04 5.88E+04 5.88E+04 6.49E+04 5.57E+04 5.38E+04 4.77E+04 2.90E+04 2.38E+04 2.30E+04 1.81E+04 1.88E+04 1.80E+05 1.73E+05 1.87E+05 1.88E+05 1.69E+05 1.82E+05 1.56E+05 1.47E+05 1.73E+05 1.46E+05 1.39E+05 1.68E+05 1.41E+05 1.71E+05 1.56E+05 7.51E+04 1.55E+05 1.51E+05 1.04E+05 5.88E+04 1.05E+05 7.03E+04 8.06E+04 2.11E+05 1.30E+05 3.17E+05 2.70E+05 2.64E+05 3.09E+05 2.48E+05 5.70E+05 5.76E+05 3.52E+05 5.46E+05 5.95E+05 4.81E+05 7.31E+05 6.46E+05 3.74E+05 5.60E+05 6.54E+05 3.51E+05 2.74E+05 3.08E+05 3.83E+05 2.07E+05 4.87E+05 3.78E+05 Fructose-1,6-bisphosphate 1.31E+07 1.49E+07 1.70E+07 1.56E+07 1.53E+07 1.48E+07 2.58E+05 3.90E+05 6.22E+05 3.34E+05 6.16E+05 2.17E+05 1.01E+06 1.17E+06 1.09E+06 8.04E+05 9.01E+05 8.94E+05 4.23E+06 2.68E+06 3.84E+06 3.15E+06 3.54E+06 6.15E+06 1.29E+07 1.22E+07 1.30E+07 1.32E+06 1.16E+07 1.33E+07 2.06E+07 2.02E+07 1.92E+07 1.92E+07 1.72E+07 1.96E+07 7.67E+07 5.82E+07 6.45E+07 6.86E+07 7.25E+07 5.82E+07 1.51E+08 1.40E+08 1.43E+08 1.31E+08 1.25E+08 1.32E+08 1.09E+08 8.16E+07 9.86E+07 1.07E+08 8.19E+07 1.14E+08 4.84E+06 5.17E+07 6.01E+07 7.60E+07 5.27E+07 8.69E+07 Cis-Aconitate 2.40E+06 2.43E+06 2.51E+06 2.42E+06 2.44E+06 2.40E+06 2.28E+05 2.40E+05 3.26E+05 2.35E+05 2.95E+05 2.44E+05 4.22E+05 4.85E+05 4.41E+05 4.84E+05 4.52E+05 4.82E+05 5.73E+05 7.23E+05 8.62E+05 4.50E+05 6.06E+05 6.11E+05 3.41E+05 4.81E+05 3.79E+05 3.44E+05 3.78E+05 4.11E+05 1.39E+06 1.54E+06 1.61E+06 1.30E+06 1.33E+06 1.68E+06 1.43E+07 1.57E+07 1.38E+07 1.39E+07 1.45E+07 1.25E+07 2.51E+07 2.08E+07 2.39E+07 2.38E+07 2.35E+07 2.35E+07 2.73E+07 2.65E+07 2.65E+07 2.85E+07 2.91E+07 3.34E+07 2.19E+07 2.04E+07 2.02E+07 1.90E+07 1.93E+07 2.29E+07 Malate 4.28E+07 4.49E+07 4.56E+07 4.38E+07 4.62E+07 4.24E+07 1.69E+07 1.76E+07 2.01E+07 1.79E+07 1.75E+07 1.76E+07 1.37E+07 1.58E+07 1.54E+07 1.57E+07 1.38E+07 1.51E+07 2.23E+07 1.83E+07 2.43E+07 1.92E+07 1.75E+07 2.32E+07 1.22E+08 1.68E+08 1.44E+08 2.00E+07 1.48E+08 1.42E+08 5.68E+07 5.95E+07 4.63E+07 5.02E+07 5.56E+07 6.02E+07 4.09E+08 4.50E+08 4.07E+08 4.20E+08 4.16E+08 3.90E+08 6.12E+08 5.55E+08 5.78E+08 5.73E+08 5.81E+08 5.84E+08 5.34E+08 5.35E+08 5.33E+08 5.80E+08 5.66E+08 5.82E+08 4.08E+08 3.89E+08 4.09E+08 3.81E+08 4.15E+08 4.03E+08 Acetyl-CoA 2.31E+05 2.46E+05 2.26E+05 1.99E+05 2.42E+05 1.87E+05 2.37E+05 2.51E+05 2.79E+05 2.51E+05 2.71E+05 2.42E+05 9.98E+05 4.07E+05 8.37E+05 5.12E+05 8.29E+05 7.90E+05 1.34E+06 1.37E+06 1.25E+06 1.50E+06 1.36E+06 1.57E+06 1.37E+06 1.57E+06 1.46E+06 6.10E+05 1.50E+06 1.38E+06 4.85E+05 4.22E+05 4.77E+05 4.94E+05 4.57E+05 5.75E+05 5.37E+06 3.08E+06 4.36E+06 3.87E+06 4.68E+06 3.91E+06 9.26E+06 7.75E+06 1.06E+07 7.55E+06 7.57E+06 6.33E+06 5.73E+06 3.99E+06 5.64E+06 6.03E+06 4.95E+06 5.95E+06 1.57E+06 1.34E+06 1.28E+06 2.39E+06 1.31E+06 1.70E+06 3-Phosphoglycerate 3.63E+05 4.67E+05 4.45E+05 5.15E+05 5.51E+05 4.87E+05 1.63E+05 1.67E+05 2.06E+05 2.13E+05 1.78E+05 1.98E+05 8.02E+05 8.51E+05 8.10E+05 9.61E+05 8.05E+05 1.01E+06 2.13E+06 1.45E+06 2.36E+06 1.67E+06 1.62E+06 2.56E+06 1.07E+06 1.35E+06 1.28E+06 4.55E+05 1.39E+06 1.30E+06 1.21E+06 1.26E+06 1.25E+06 1.23E+06 1.16E+06 1.34E+06 4.03E+06 4.55E+06 3.38E+06 3.31E+06 4.03E+06 2.97E+06 7.93E+06 5.70E+06 8.77E+06 8.68E+06 8.69E+06 1.07E+07 5.07E+06 8.75E+06 3.53E+06 5.59E+06 5.46E+06 6.62E+06 7.79E+06 3.68E+06 3.65E+06 2.05E+06 3.59E+06 4.04E+06 metabolite_name m/z KEGG_ID Glucose-6-phosphate 259 C00668 Citrate 191 C00158 a-Ketoglutarate 145 C00026 Succinate 117 C00042 Phosphoenolpyruvate 167 C00074 Pyruvate 87 C00022 Fructose-6-phosphate 259 C00085 Glyceraldehyde-3-phosphate 169 C00118 Fumarate 115 C00122 Oxaloacetate 131 C00036 Fructose-1,6-bisphosphate 339 C05378 Cis-Aconitate 173 C00417 Malate 133 C00711 Acetyl-CoA 808 C00024 3-Phosphoglycerate 185 C00197