metabolite_name MXP500L-0-5711_1036867631_66_0_1_1_00_1036867045_2_R22V2 MXP500L-0-5711_1036867631_71_0_1_1_00_1036867050_3_R22V3 MXP500L-0-5711_1036867631_42_0_1_1_00_1036867079_5_R24V2 MXP500L-0-5711_1036867631_89_0_1_1_00_1036867083_6_R24V3 MXP500L-0-5711_1036867631_94_0_1_1_00_1036867109_8_R26V2 MXP500L-0-5711_1036867631_40_0_1_1_00_1036867113_9_R26V3 MXP500L-0-5711_1036867631_72_0_1_1_00_1036866380_11_R28V2 MXP500L-0-5711_1036867631_10_0_1_1_00_1036866394_12_R28V3 MXP500L-0-5711_1036867631_46_0_1_1_00_1036866405_13_R29V2 MXP500L-0-5711_1036867631_60_0_1_1_00_1036866410_14_R29V3 MXP500L-0-5711_1036867631_52_0_1_1_00_1036866424_15_R30V2 MXP500L-0-5711_1036867631_19_0_1_1_00_1036866439_16_R30V3 MXP500L-0-5711_1036867631_82_0_1_1_00_1036866477_20_R22V2 MXP500L-0-5711_1036867631_30_0_1_1_00_1036866481_21_R22V3 MXP500L-0-5711_1036867631_48_0_1_1_00_1036866507_23_R24V2 MXP500L-0-5711_1036867631_58_0_1_1_00_1036866511_24_R24V3 MXP500L-0-5711_1036867631_95_0_1_1_00_1036866531_26_R26V2 MXP500L-0-5711_1036867631_06_0_1_1_00_1036866545_27_R26V3 MXP500L-0-5711_1036867631_93_0_1_1_00_1036866564_29_R28V2 MXP500L-0-5711_1036867631_45_0_1_1_00_1036865818_30_R28V3 MXP500L-0-5711_1036867631_24_0_1_1_00_1036865822_31_R29V2 MXP500L-0-5711_1036867631_33_0_1_1_00_1036865837_32_R29V3 MXP500L-0-5711_1036867631_05_0_1_1_00_1036865841_33_R30V2 MXP500L-0-5711_1036867631_17_0_1_1_00_1036865856_34_R30V3 MXP500L-0-5711_1036867631_66_0_1_1_00_1036867045_2_D1 MXP500L-0-5711_1036867631_42_0_1_1_00_1036867079_5_D2 MXP500L-0-5711_1036867631_67_0_1_1_00_1036867128_10_D3 MXP500L-0-5711_1036867631_72_0_1_1_00_1036866380_11_D4 MXP500L-0-5711_1036867631_46_0_1_1_00_1036866405_13_D5 MXP500L-0-5711_1036867631_52_0_1_1_00_1036866424_15_D6 MXP500L-0-5711_1036867631_82_0_1_1_00_1036866477_20_D1 MXP500L-0-5711_1036867631_48_0_1_1_00_1036866507_23_D2 MXP500L-0-5711_1036867631_07_0_1_1_00_1036866550_28_D3 MXP500L-0-5711_1036867631_93_0_1_1_00_1036866564_29_D4 MXP500L-0-5711_1036867631_24_0_1_1_00_1036865822_31_D5 MXP500L-0-5711_1036867631_05_0_1_1_00_1036865841_33_D6 TMAO 1.44 1.61 2.2 2.68 2.07 3.2 1.28 1.72 1.56 1.26 1.4 2.37 1.65 2.1 2.53 3.03 2.4 4.14 1.53 2.07 1.32 1.39 1.84 2.14 1.44 2.2 7.54 1.28 1.56 1.4 1.65 2.53 8.37 1.53 1.32 1.84 Ala 393 346 363 322 320 377 281 286 351 438 327 462 414 424 454 374 400 494 383 362 326 436 410 431 393 363 433 281 351 327 414 454 549 383 326 410 Arg 87.2 80.7 84.4 80.9 79.6 90.8 73.8 86.2 102 90.6 68.7 93.4 115 121 111 105 95.4 118 107 108 90.9 95.7 95.2 93.5 87.2 84.4 103 73.8 102 68.7 115 111 122 107 90.9 95.2 Asn 37.8 40.1 59 63.9 48.7 52.9 47.9 51.4 73.9 65.9 39.2 57.7 39.3 50.2 71.7 69.1 57.2 69.4 62.4 59.3 68.6 70.1 49.8 51.8 37.8 59 50.8 47.9 73.9 39.2 39.3 71.7 61.5 62.4 68.6 49.8 Asp 6.82 29.5 2.53 12.3 10.9 9.64 2.72 4.19 4.25 21.6 2.27 12.8 8.44 11 7.53 6.14 8.77 12 9.25 9.32 9.87 8.92 9.62 10 6.82 2.53 3.19 2.72 4.25 2.27 8.44 7.53 10.3 9.25 9.87 9.62 Cys 84.6 95.1 77.5 63.3 78.4 68.7 76 75.7 101 92.8 93.9 95.2 114 108 103 90.2 114 102 106 103 98.4 79.2 97.2 85.4 84.6 77.5 84.5 76 101 93.9 114 103 114 106 98.4 97.2 Gln 632 488 589 653 573 672 565 650 709 620 481 572 651 590 679 703 677 853 720 757 627 605 548 511 632 589 702 565 709 481 651 679 818 720 627 548 Glu 36.3 69.7 22.7 52.6 91.7 88.4 20.3 34.2 45.1 73 17.6 66 28.5 41.1 24.4 17 41.8 43.2 24.8 39.5 34.2 22.1 24.3 24.3 36.3 22.7 30.9 20.3 45.1 17.6 28.5 24.4 36.4 24.8 34.2 24.3 Gly 179 165 209 211 265 275 275 265 361 313 258 286 189 195 245 233 311 353 361 316 331 312 311 263 179 209 262 275 361 258 189 245 311 361 331 311 His 80.9 76.1 88.2 90.1 84.1 85.5 75.8 86.7 102 77.4 84.7 102 84.9 86.6 102 98 101 110 99.6 104 95.5 76.6 99.3 92.9 80.9 88.2 80 75.8 102 84.7 84.9 102 93.9 99.6 95.5 99.3 Ile 63.2 67.3 107 97.8 67.3 69.8 57.8 69.9 105 64 64.7 102 62.2 76 124 105 75.8 83.9 73.6 79.6 91.5 61.5 69.4 93.8 63.2 107 62.3 57.8 105 64.7 62.2 124 71.4 73.6 91.5 69.4 Leu 92.5 105 149 165 124 128 110 121 188 101 125 194 93.4 124 173 178 147 156 145 140 157 95.2 136 172 92.5 149 97.2 110 188 125 93.4 173 115 145 157 136 Lys 131 143 133 124 130 162 132 136 209 146 142 227 139 175 177 144 160 219 170 167 174 139 180 229 131 133 102 132 209 142 139 177 126 170 174 180 Met 21.2 14.8 27.2 29.8 22.8 31.2 26.4 25.9 36.1 24.8 25.2 39.3 20.2 15.9 30.2 31.3 25.3 36.9 31.6 28.6 32.1 23 26.8 34.9 21.2 27.2 21.3 26.4 36.1 25.2 20.2 30.2 23.8 31.6 32.1 26.8 Phe 57 51.2 71.5 83.3 48.5 55.4 48.2 50.1 71.1 55.9 66.6 80.3 58.3 64.5 82.9 87.2 55.1 66.9 64 61.9 65.4 55.2 72.9 76.5 57 71.5 51.6 48.2 71.1 66.6 58.3 82.9 63.6 64 65.4 72.9 Pro 171 198 119 151 162 207 163 223 270 200 118 223 177 238 140 165 187 260 204 257 238 197 137 198 171 119 173 163 270 118 177 140 205 204 238 137 Ser 75.8 79.5 90.7 112 108 122 120 136 168 122 119 172 84.5 87.8 121 129 132 162 165 174 158 128 154 163 75.8 90.7 85.7 120 168 119 84.5 121 114 165 158 154 Thr 119 114 94.4 82.5 111 145 114 139 204 171 92.3 147 124 137 114 93.3 133 185 153 168 185 171 110 135 119 94.4 101 114 204 92.3 124 114 123 153 185 110 Trp 60 49.8 81.8 72.9 64 62.5 56.9 66.9 57.5 39.6 55.2 75.3 63.8 64.2 94.5 83.8 86.6 76.4 74.4 82.3 56.1 42.2 64.8 70 60 81.8 54.8 56.9 57.5 55.2 63.8 94.5 63.2 74.4 56.1 64.8 Tyr 56.4 57.1 50.1 70.2 45.4 55.8 64.3 53.8 62.8 46 53.9 88.9 56.7 65.6 57.4 73 52.9 68.6 81.3 62.2 56.9 44.4 60.3 80.7 56.4 50.1 51.4 64.3 62.8 53.9 56.7 57.4 58.8 81.3 56.9 60.3 Val 175 217 209 191 187 204 174 198 261 159 215 269 176 248 226 212 210 236 213 221 216 152 227 233 175 209 162 174 261 215 176 226 183 213 216 227 1-Met-His 2.82 2.04 5.14 2.61 3.3 2.73 2.67 2.73 6.17 4.4 4.22 4.59 2.8 2.47 6.07 2.97 3.82 3.41 3.48 3.44 5.55 4.26 5.17 4.12 2.82 5.14 3.71 2.67 6.17 4.22 2.8 6.07 4.42 3.48 5.55 5.17 3-Met-His 0.267 0.227 24.2 0.265 0.51 1.35 1.61 0.922 4.98 3.31 7.5 8.53 0.27 0.254 26.7 0.287 0.555 1.48 1.99 1.11 4.22 3.07 8.61 7.93 0.267 24.2 0.358 1.61 4.98 7.5 0.27 26.7 0.385 1.99 4.22 8.61 AABA 10.7 9.31 9.13 9.12 11.9 9.21 12.1 14.8 16.2 12.3 13.2 16.3 10.7 10.1 10.9 9.17 13.4 10.3 15 16 13.1 11 15.3 14.6 10.7 9.13 7.26 12.1 16.2 13.2 10.7 10.9 8.29 15 13.1 15.3 ADMA 0.497 0.512 0.366 0.401 0.517 0.513 0.421 0.457 0.447 0.424 0.509 0.574 0.516 0.548 0.433 0.432 0.568 0.61 0.512 0.511 0.417 0.405 0.577 0.54 0.497 0.366 0.504 0.421 0.447 0.509 0.516 0.433 0.605 0.512 0.417 0.577 alpha-AAA 0.699 0.721 0.855 0.594 0.708 0.859 0.529 0.618 1.16 0.831 0.693 1.16 0.708 0.805 0.914 0.592 0.762 0.988 0.654 0.74 1.05 0.712 0.957 1.09 0.699 0.855 0.539 0.529 1.16 0.693 0.708 0.914 0.683 0.654 1.05 0.957 Betaine 22.4 20.3 28 25.9 27 30.8 23 27.2 30.7 25.6 21.8 21.7 19.6 18.2 28.2 24.1 23.9 30.4 23.5 25.2 23.1 22.1 15.6 15 22.4 28 38.3 23 30.7 21.8 19.6 28.2 40.1 23.5 23.1 15.6 Cit 25.5 26.3 23.3 20.8 23.1 26.4 19.5 22.4 37.5 31.2 26.2 29.3 26.3 26.8 26.9 23.2 27.5 33.7 24.4 27.6 33.7 31.2 30.9 25.5 25.5 23.3 37.1 19.5 37.5 26.2 26.3 26.9 44.6 24.4 33.7 30.9 Creatinine 45.7 36.3 63 57.8 56.5 54.2 48.8 50.6 93.6 80 59.4 64.4 46.3 43.7 71.1 62.1 65 65 60 56.8 80.4 79.3 66.1 58.6 45.7 63 62.8 48.8 93.6 59.4 46.3 71.1 73.8 60 80.4 66.1 HArg 3.62 3.76 2.08 1.5 2.63 3 1.56 1.89 3.55 3.33 2.32 2.34 3.83 4.5 2.5 1.65 3.2 3.85 1.9 2.14 3.24 3.5 2.94 2.18 3.62 2.08 1.69 1.56 3.55 2.32 3.83 2.5 2.01 1.9 3.24 2.94 HCys 6.56 9.93 7.97 7.94 12.8 10.1 7.56 6.69 12.4 14.4 7.91 10.3 10.9 12.3 14.7 13.8 18 14.5 10.9 10.6 12.2 16.2 9.43 10.4 6.56 7.97 21.9 7.56 12.4 7.91 10.9 14.7 33.1 10.9 12.2 9.43 Kynurenine 1.95 1.68 1.8 1.63 2 1.99 2.02 1.73 1.93 1.28 1.72 1.97 2.09 1.97 1.91 1.68 2.36 2.35 2.6 1.96 1.73 1.3 2.11 1.96 1.95 1.8 1.98 2.02 1.93 1.72 2.09 1.91 2.39 2.6 1.73 2.11 Met-SO 0.538 0.607 1.04 0.956 0.504 0.547 0.507 0.571 0.536 0.437 0.444 0.818 0.55 0.653 1.24 1.06 0.519 0.796 0.559 0.636 0.598 0.466 0.595 0.833 0.538 1.04 0.547 0.507 0.536 0.444 0.55 1.24 0.718 0.559 0.598 0.595 Orn 45.3 52.9 50.3 51.7 53.6 56.1 42.7 63.8 73.3 50.1 37.3 54.4 51 68.8 75.6 64 84.6 97.9 72.2 94.3 94.5 74.2 60.9 67.4 45.3 50.3 80.5 42.7 73.3 37.3 51 75.6 135 72.2 94.5 60.9 ProBetaine 1.58 1.49 0.611 0.444 3.36 6.51 3.31 7.55 0.83 0.431 0.952 0.406 1.5 1.6 0.62 0.415 3.55 6.99 3.77 7.61 0.681 0.368 0.916 0.313 1.58 0.611 28.4 3.31 0.83 0.952 1.5 0.62 27.9 3.77 0.681 0.916 Sarcosine 3.98 3.36 3.3 3.2 4.16 4.11 3.07 3.97 3.75 3.35 7.09 4.55 1.02 1.08 1.51 1.1 1.62 2.53 1.97 1.98 1.47 1.32 1.96 2.11 3.98 3.3 4.14 3.07 3.75 7.09 1.02 1.51 1.49 1.97 1.47 1.96 SDMA 0.397 0.325 0.424 0.44 0.521 0.5 0.429 0.435 0.66 0.513 0.471 0.519 0.437 0.392 0.485 0.473 0.646 0.604 0.54 0.491 0.594 0.535 0.513 0.479 0.397 0.424 0.552 0.429 0.66 0.471 0.437 0.485 0.667 0.54 0.594 0.513 t4-OH-Pro 4.74 6.19 4.81 4.55 17.4 7.04 7.11 11.4 20.2 15.7 7.76 12.9 5.04 7.23 5.44 4.72 20.3 8.92 8.92 12.7 17.9 16.4 8.84 11.6 4.74 4.81 6.69 7.11 20.2 7.76 5.04 5.44 7.4 8.92 17.9 8.84 Taurine 137 307 58.7 231 ? 258 73.5 100 57.2 327 52.8 ? 119 85.7 97.9 78.8 124 144 97.4 128 85.6 84.3 96.8 115 137 58.7 78 73.5 57.2 52.8 119 97.9 117 97.4 85.6 96.8 TrpBetaine 0.852 1.84 2.03 2.38 0.467 0.498 1.25 1.31 0.113 0.075 0.706 0.835 0.859 2.06 2.34 2.42 0.52 0.606 1.58 1.35 0.1 0.074 0.765 0.7 0.852 2.03 1.36 1.25 0.113 0.706 0.859 2.34 1.56 1.58 0.1 0.765 beta-Ala 3.04 3.56 9.63 2.34 2.48 2.29 1.81 1.96 2.33 3.63 2.03 3.05 2.94 2.62 12.2 1.99 2.28 2.41 2.38 2.25 2.71 2.55 2.61 2.26 3.04 9.63 2.01 1.81 2.33 2.03 2.94 12.2 2.53 2.38 2.71 2.61 GABA 0.163 0.164 0.139 0.158 0.197 0.181 0.138 0.169 0.177 0.185 0.151 0.175 0.17 0.19 0.175 0.15 0.228 0.222 0.187 0.22 0.173 0.179 0.209 0.165 0.163 0.139 0.137 0.138 0.177 0.151 0.17 0.175 0.173 0.187 0.173 0.209 Putrescine 0.09 0.165 0.062 0.107 0.298 0.244 0.114 0.131 0.2 0.374 0.12 0.199 0.119 0.151 0.095 0.09 0.233 0.248 0.143 0.151 0.23 0.258 0.169 0.13 0.09 0.062 0.099 0.114 0.2 0.12 0.119 0.095 0.134 0.143 0.23 0.169 Serotonin 0.289 1.25 0.152 0.834 2.29 1.67 0.32 0.459 0.202 2.39 0.081 2.25 0.813 0.793 0.452 0.427 0.882 0.862 0.804 0.839 0.535 0.561 1.07 0.723 0.289 0.152 0.377 0.32 0.202 0.081 0.813 0.452 0.646 0.804 0.535 1.07 HipAcid 0.602 0.449 7.56 10.8 5.6 3.48 1.31 3.05 0.63 0.252 0.693 2.06 0.507 0.493 8.35 11.5 6.66 4.08 1.68 3.42 0.493 0.22 0.772 1.76 0.602 7.56 9.97 1.31 0.63 0.693 0.507 8.35 11.7 1.68 0.493 0.772 Cortisol 0.146 0.211 0.21 0.149 0.173 0.161 0.153 0.186 0.218 0.113 0.151 0.191 0.169 0.253 0.212 0.182 0.188 0.171 0.189 0.198 0.206 0.118 0.185 0.182 0.146 0.21 0.143 0.153 0.218 0.151 0.169 0.212 0.149 0.189 0.206 0.185 3-IAA 1.03 1.09 1.63 4.94 1.99 2.16 1.45 1.53 2.36 1.11 3.61 4.85 1.11 1.33 1.83 5.1 2.39 2.61 1.77 1.78 2.02 1.19 4.23 4.38 1.03 1.63 1.01 1.45 2.36 3.61 1.11 1.83 1.22 1.77 2.02 4.23 3-IPA 0.562 0.403 2.53 2.39 2.27 2.38 0.039 0.01 0.047 0.014 0.225 0.383 0.572 0.527 2.83 2.41 2.77 2.91 0.052 0.015 0.037 0.017 0.271 0.368 0.562 2.53 2.14 0.039 0.047 0.225 0.572 2.83 2.6 0.052 0.037 0.271 Hypoxanthine 0.894 1.4 0.486 0.69 1.28 1.58 0.599 1.11 1.05 1.12 1.1 1.45 2.91 4.12 4.01 3.58 6.81 8.54 4.7 6.01 4.92 4.53 3.84 4.93 0.894 0.486 1.07 0.599 1.05 1.1 2.91 4.01 6.31 4.7 4.92 3.84 Xanthine 0.242 0.253 0.173 0.204 0.494 0.519 0.268 0.343 0.412 0.353 0.359 0.411 0.45 0.57 0.588 0.499 1.08 1.53 0.724 0.935 1.03 0.847 0.802 1.05 0.242 0.173 0.379 0.268 0.412 0.359 0.45 0.588 1.43 0.724 1.03 0.802 Choline 3.44 4.32 4.45 4.39 5.53 5.07 2.74 3.36 4.61 4.29 5.29 6.86 3.61 4.45 5.55 4.3 5.95 6.03 3.97 4.68 4.63 4.28 6.66 6.09 3.44 4.45 4.56 2.74 4.61 5.29 3.61 5.55 6.23 3.97 4.63 6.66 metabolite_name Precursor Ion Fragment Ion 1-Met-His 305.1 124.1 3-IAA 176 130.1 3-IPA 190.1 130.1 3-Met-His 305.1 168.2 AABA 239 104.1 ADMA 338.2 46 Ala 225.2 44.2 alpha-AAA 297.1 144.2 Arg 310 217 Asn 268.2 77 Asp 269.2 116.2 beta-Ala 225.1 90.1 Betaine 118.1 59.1 Choline 104 58.1 Cit 311.2 113.1 Cortisol 363.1 121.1 Creatinine 114.1 44.1 Cys 392 177 GABA 239 104.1 Gln 282.2 130 Glu 283.2 130.2 Gly 211.2 75.9 HArg 324.1 189.1 HCys 406 236.9 HipAcid 180.1 105 His 291.1 110.2 Hypoxanthine 137.1 110.1 Ile 267.3 69 Kynurenine 344.2 146.2 Leu 267.3 43 Lys 417.2 324.2 Met 285.1 104.2 Met-SO 301.2 88.1 Orn 403.2 310.2 Phe 301.2 120.2 Pro 251.2 70.3 ProBetaine 144.1 84.1 Putrescine 359.1 266.1 Sarcosine 225 90.1 SDMA 338.2 70.1 Ser 241.2 60 Serotonin 312.3 160.2 t4-OH-Pro 267.2 68 Taurine 261 126.1 Thr 255.2 74.1 TMAO 75.9 59.1 Trp 340.2 188.2 TrpBetaine 247 188.1 Tyr 317.2 136.1 Val 253.2 72.2 Xanthine 153 110.1