#METABOLOMICS WORKBENCH DATATRACK_ID:3902 STUDY_ID:ST002660 ANALYSIS_ID:AN004332 VERSION 1 CREATED_ON 05-02-2023 #PROJECT PR:PROJECT_TITLE MoTrPAC PR:PROJECT_SUMMARY MoTrPAC is a national research consortium designed to discover and perform PR:PROJECT_SUMMARY preliminary characterization of the range of molecular transducers (the PR:PROJECT_SUMMARY "molecular map") that underlie the effects of physical activity in humans. The PR:PROJECT_SUMMARY program's goal is to study the molecular changes that occur during and after PR:PROJECT_SUMMARY exercise and ultimately to advance the understanding of how physical activity PR:PROJECT_SUMMARY improves and preserves health. Preclinical and clinical studies will examine the PR:PROJECT_SUMMARY systemic effects of endurance and resistance exercise across a range of ages and PR:PROJECT_SUMMARY fitness levels by molecular probing of multiple tissues before and after acute PR:PROJECT_SUMMARY and chronic exercise. This program is the largest targeted NIH investment of PR:PROJECT_SUMMARY funds into the mechanisms of how physical activity improves health and prevents PR:PROJECT_SUMMARY disease. The MoTrPAC program is supported by the NIH Common Fund and is managed PR:PROJECT_SUMMARY by a trans-agency working group representing multiple NIH institutes and PR:PROJECT_SUMMARY centers, led by the NIH Office of Strategic Coordination, National Institute of PR:PROJECT_SUMMARY Arthritis and Musculoskeletal and Skin Diseases, National Institute of Diabetes PR:PROJECT_SUMMARY and Digestive and Kidney Diseases, National Institute on Aging, and National PR:PROJECT_SUMMARY Institute of Biomedical Imaging and Bioengineering. MoTrPAC Steering Committee: PR:PROJECT_SUMMARY Wendy Kohrt, Chair, Russ Tracy, Co-Chair; NIH Program Manager, Concepcion PR:PROJECT_SUMMARY Nierras. Euan Ashley and Matthew Wheeler are the PIs for the Motrpac PR:PROJECT_SUMMARY Bioinformatics / Data Coordination Center. PR:INSTITUTE MoTrPAC PR:LAST_NAME Ashley PR:FIRST_NAME Euan PR:ADDRESS Falk Building CV267, 870 Quarry Road, Stanford, California 94305 PR:EMAIL motrpac-data-deposition@lists.stanford.edu PR:PHONE (650) 725-1846 PR:DOI http://dx.doi.org/10.21228/M8V97D #STUDY ST:STUDY_TITLE MoTrPAC: Endurance exercise training study in young adult rats, Rat ST:STUDY_TITLE Gastrocnemius Powder - Targeted Acyl-CoA ST:STUDY_SUMMARY The goal of the endurance exercise training study in young adult rats (internal ST:STUDY_SUMMARY code: PASS1B-06) was to perform exercise training studies in adult (6 month) ST:STUDY_SUMMARY F344 rats, and from these rats collect as many tissues as feasible in order to ST:STUDY_SUMMARY provide high quality samples for detailed analysis by chemical analysis sites. ST:STUDY_SUMMARY Tissues were collected from 10-12 rats sedentary control rats concurrent with ST:STUDY_SUMMARY the collection of the 8-week training groups. The 8-week training group and ST:STUDY_SUMMARY controls were from the same cohort and same age at euthanasia (either 8). For ST:STUDY_SUMMARY the older age group, an additional set of controls (n=5-6) were collected with ST:STUDY_SUMMARY the 1-2 week training group. Rats were either sedentary or underwent an exercise ST:STUDY_SUMMARY training program. Rats were exercised on the rodent treadmill 5 days per week ST:STUDY_SUMMARY using a progressive training protocol designed to exercise the rats at ST:STUDY_SUMMARY approximately 70% of VO2max as outlined in the Table on the next page. Training ST:STUDY_SUMMARY was performed no earlier than 10:00 am and no later than 5:00 pm over 5 ST:STUDY_SUMMARY consecutive days per week. Training was initiated with the treadmill set at 70% ST:STUDY_SUMMARY of VO2 max (see tables) and 5 degrees grade for 20 minutes. The duration of ST:STUDY_SUMMARY exercise was increased by one minute each day until day 31 of training (start of ST:STUDY_SUMMARY week 7), when a duration of 50 min was reached. Speed and grade of each training ST:STUDY_SUMMARY session increased in larger increments due to treadmill parameters. The highest ST:STUDY_SUMMARY intensity and duration of training began on day 31. This intensity was ST:STUDY_SUMMARY maintained for the final 10 days of the protocol to ensure steady state had been ST:STUDY_SUMMARY achieved. If any rats were unable to perform at least 4 days of training per ST:STUDY_SUMMARY week they were removed from the study and euthanized. It is important to note ST:STUDY_SUMMARY that the starting treadmill speed varied depending on the sex and age of the ST:STUDY_SUMMARY rat. The initial and maximum speeds were based on VO2max measurements obtained ST:STUDY_SUMMARY during the pre-training testing of the compliant rats. Rats assigned to the ST:STUDY_SUMMARY control group followed a schedule similar to the training group. They were ST:STUDY_SUMMARY placed in one lane on the treadmill for 15 minutes/day, 5 days per week. The ST:STUDY_SUMMARY treadmill was set at 0 m/min at an incline that corresponded to the incline ST:STUDY_SUMMARY being used by the training group. ST:INSTITUTE Duke University ST:DEPARTMENT Duke Molecular Physiology Institute ST:LABORATORY Metabolomics Core Laboratory ST:LAST_NAME Newgard ST:FIRST_NAME Christopher ST:ADDRESS 300 N Duke St, Durham, NC 27701 ST:EMAIL chris.newgard@duke.edu ST:PHONE (919) 668-6059 ST:SUBMIT_DATE 2023-04-25 #SUBJECT SU:SUBJECT_TYPE Mammal SU:SUBJECT_SPECIES Rattus norvegicus SU:TAXONOMY_ID 10116 #SUBJECT_SAMPLE_FACTORS: SUBJECT(optional)[tab]SAMPLE[tab]FACTORS(NAME:VALUE pairs separated by |)[tab]Additional sample data SUBJECT_SAMPLE_FACTORS 1628FB23-6F66-47D4-8D82-63C87726F0FD 90245015514 Group:Control | Timepoint:8 weeks of training or control time | Sex:Female raw_file=Motrpac_PASS1B_Gastroc_CoA_081320_a035.zip SUBJECT_SAMPLE_FACTORS 69FD4884-786D-4F2A-97B1-6174FBD25D60 90248015514 Group:Control | Timepoint:8 weeks of training or control time | Sex:Female raw_file=Motrpac_PASS1B_Gastroc_CoA_081320_a048.zip SUBJECT_SAMPLE_FACTORS 07AF7369-F082-4CA7-99D5-D973F4A162C9 90252015514 Group:Control | Timepoint:8 weeks of training or control time | Sex:Female raw_file=Motrpac_PASS1B_Gastroc_CoA_081320_a028.zip SUBJECT_SAMPLE_FACTORS F9BEE1FA-E2DB-4BE4-A79C-99D585D6FD17 90265015514 Group:Control | Timepoint:8 weeks of training or control time | Sex:Female raw_file=Motrpac_PASS1B_Gastroc_CoA_081320_a075.zip SUBJECT_SAMPLE_FACTORS A77AC89A-1D9E-4516-9DA4-2BE99C8126EF 90266015514 Group:Control | Timepoint:8 weeks of training or control time | Sex:Female raw_file=Motrpac_PASS1B_Gastroc_CoA_081320_a055.zip SUBJECT_SAMPLE_FACTORS BC49E4EF-E2FE-4269-BAF0-461F768BD95D 90217015514 Group:Control | Timepoint:8 weeks of training or control time | Sex:Male raw_file=Motrpac_PASS1B_Gastroc_CoA_081320_a037.zip SUBJECT_SAMPLE_FACTORS 0559B193-BED3-4170-B045-10A2B6441CB6 90229015514 Group:Control | Timepoint:8 weeks of training or control time | Sex:Male raw_file=Motrpac_PASS1B_Gastroc_CoA_081320_a063.zip SUBJECT_SAMPLE_FACTORS 90CFE5A4-76FE-4458-A2B1-A66F0B60118E 90232015514 Group:Control | Timepoint:8 weeks of training or control time | Sex:Male raw_file=Motrpac_PASS1B_Gastroc_CoA_081320_a059.zip SUBJECT_SAMPLE_FACTORS F0D83B29-8EFA-4CDE-B1AA-2358AC220ECF 90237015514 Group:Control | Timepoint:8 weeks of training or control time | Sex:Male raw_file=Motrpac_PASS1B_Gastroc_CoA_081320_a041.zip SUBJECT_SAMPLE_FACTORS FCE9ABE6-B60B-4934-BAE5-56AF8B11ECEC 90239015514 Group:Control | Timepoint:8 weeks of training or control time | Sex:Male raw_file=Motrpac_PASS1B_Gastroc_CoA_081320_a066.zip SUBJECT_SAMPLE_FACTORS - 80008815502_1 Group:QC-ExternalStandard | Timepoint:0 hour | Sex:- raw_file=Motrpac_PASS1B_Gastroc_CoA_081320_a023.zip SUBJECT_SAMPLE_FACTORS - 80008815502_2 Group:QC-ExternalStandard | Timepoint:0 hour | Sex:- raw_file=Motrpac_PASS1B_Gastroc_CoA_081320_a042.zip SUBJECT_SAMPLE_FACTORS - 80008815502_3 Group:QC-ExternalStandard | Timepoint:0 hour | Sex:- raw_file=Motrpac_PASS1B_Gastroc_CoA_081320_a061.zip SUBJECT_SAMPLE_FACTORS - 80008815502_4 Group:QC-ExternalStandard | Timepoint:0 hour | Sex:- raw_file=Motrpac_PASS1B_Gastroc_CoA_081320_a079.zip SUBJECT_SAMPLE_FACTORS - 80009825502_1 Group:QC-ExternalStandard | Timepoint:0 hour | Sex:- raw_file=Motrpac_PASS1B_Gastroc_CoA_081320_a024.zip SUBJECT_SAMPLE_FACTORS - 80009825502_2 Group:QC-ExternalStandard | Timepoint:0 hour | Sex:- raw_file=Motrpac_PASS1B_Gastroc_CoA_081320_a043.zip SUBJECT_SAMPLE_FACTORS - 80009825502_3 Group:QC-ExternalStandard | Timepoint:0 hour | Sex:- raw_file=Motrpac_PASS1B_Gastroc_CoA_081320_a062.zip SUBJECT_SAMPLE_FACTORS - 80009825502_4 Group:QC-ExternalStandard | Timepoint:0 hour | Sex:- raw_file=Motrpac_PASS1B_Gastroc_CoA_081320_a080.zip SUBJECT_SAMPLE_FACTORS B73AB139-7210-4498-9CCF-E1DBE6EBA71C 90559015514 Group:Training | Timepoint:1 week of training or control time | Sex:Female raw_file=Motrpac_PASS1B_Gastroc_CoA_081320_a073.zip SUBJECT_SAMPLE_FACTORS EA5C8932-9325-4DA5-96BB-50CD49CEDD10 90560015514 Group:Training | Timepoint:1 week of training or control time | Sex:Female raw_file=Motrpac_PASS1B_Gastroc_CoA_081320_a031.zip SUBJECT_SAMPLE_FACTORS 0645F621-878C-4C9B-84A6-58862BAA17D9 90564015514 Group:Training | Timepoint:1 week of training or control time | Sex:Female raw_file=Motrpac_PASS1B_Gastroc_CoA_081320_a032.zip SUBJECT_SAMPLE_FACTORS 68083256-8DAA-4185-B446-0CAF600474B5 90567015514 Group:Training | Timepoint:1 week of training or control time | Sex:Female raw_file=Motrpac_PASS1B_Gastroc_CoA_081320_a046.zip SUBJECT_SAMPLE_FACTORS 6A013AA1-4D1E-4B75-B691-6BA22D928E51 90571015514 Group:Training | Timepoint:1 week of training or control time | Sex:Female raw_file=Motrpac_PASS1B_Gastroc_CoA_081320_a026.zip SUBJECT_SAMPLE_FACTORS 6D680EA2-C62B-4A35-8B6E-2ED6A79CB017 90421015514 Group:Training | Timepoint:1 week of training or control time | Sex:Male raw_file=Motrpac_PASS1B_Gastroc_CoA_081320_a067.zip SUBJECT_SAMPLE_FACTORS 53F914B0-FD4F-4340-84A6-48341EAB3798 90422015514 Group:Training | Timepoint:1 week of training or control time | Sex:Male raw_file=Motrpac_PASS1B_Gastroc_CoA_081320_a030.zip SUBJECT_SAMPLE_FACTORS D350D633-8D95-4783-99F2-BB8294D2EC32 90423015514 Group:Training | Timepoint:1 week of training or control time | Sex:Male raw_file=Motrpac_PASS1B_Gastroc_CoA_081320_a068.zip SUBJECT_SAMPLE_FACTORS 0DBFEB04-1B58-43CF-BAFD-9AA9915B67F6 90426015514 Group:Training | Timepoint:1 week of training or control time | Sex:Male raw_file=Motrpac_PASS1B_Gastroc_CoA_081320_a047.zip SUBJECT_SAMPLE_FACTORS 10E282EB-1DBA-406E-BD5D-81027083A01D 90430015514 Group:Training | Timepoint:1 week of training or control time | Sex:Male raw_file=Motrpac_PASS1B_Gastroc_CoA_081320_a058.zip SUBJECT_SAMPLE_FACTORS B137E81D-A9DE-4E3A-8E2B-AD6C22920B7E 90576015514 Group:Training | Timepoint:2 weeks of training | Sex:Female raw_file=Motrpac_PASS1B_Gastroc_CoA_081320_a029.zip SUBJECT_SAMPLE_FACTORS DC8B35E8-4AA8-4829-8569-F223D069620C 90578015514 Group:Training | Timepoint:2 weeks of training | Sex:Female raw_file=Motrpac_PASS1B_Gastroc_CoA_081320_a057.zip SUBJECT_SAMPLE_FACTORS 8904857C-2073-4BBA-AC7C-1EC239E5BFF7 90581015514 Group:Training | Timepoint:2 weeks of training | Sex:Female raw_file=Motrpac_PASS1B_Gastroc_CoA_081320_a036.zip SUBJECT_SAMPLE_FACTORS 1F9BD644-303F-43E7-94BE-FF6654306F5E 90585015514 Group:Training | Timepoint:2 weeks of training | Sex:Female raw_file=Motrpac_PASS1B_Gastroc_CoA_081320_a077.zip SUBJECT_SAMPLE_FACTORS 0409BED3-F9FE-4C06-9920-74F5E5CA04A3 90587015514 Group:Training | Timepoint:2 weeks of training | Sex:Female raw_file=Motrpac_PASS1B_Gastroc_CoA_081320_a070.zip SUBJECT_SAMPLE_FACTORS 4E974304-21EB-42E8-A729-A7FB6B406E64 90439015514 Group:Training | Timepoint:2 weeks of training | Sex:Male raw_file=Motrpac_PASS1B_Gastroc_CoA_081320_a064.zip SUBJECT_SAMPLE_FACTORS 6527EC12-E7EB-4F17-BF0A-0AC7CD1819A0 90441015514 Group:Training | Timepoint:2 weeks of training | Sex:Male raw_file=Motrpac_PASS1B_Gastroc_CoA_081320_a033.zip SUBJECT_SAMPLE_FACTORS AEB1611A-F29E-43F8-B9F3-A2BC4F9EB504 90444015514 Group:Training | Timepoint:2 weeks of training | Sex:Male raw_file=Motrpac_PASS1B_Gastroc_CoA_081320_a051.zip SUBJECT_SAMPLE_FACTORS FDA87A8D-3634-4C42-9A1A-0EA03B58BB01 90449015514 Group:Training | Timepoint:2 weeks of training | Sex:Male raw_file=Motrpac_PASS1B_Gastroc_CoA_081320_a045.zip SUBJECT_SAMPLE_FACTORS CDCFA3F1-07ED-4737-A36D-15EFEC325AA5 90450015514 Group:Training | Timepoint:2 weeks of training | Sex:Male raw_file=Motrpac_PASS1B_Gastroc_CoA_081320_a038.zip SUBJECT_SAMPLE_FACTORS 2E37478F-525F-4E5E-A882-EE75FD0CFB29 90406015514 Group:Training | Timepoint:4 weeks of training | Sex:Female raw_file=Motrpac_PASS1B_Gastroc_CoA_081320_a060.zip SUBJECT_SAMPLE_FACTORS A9CE3E3D-31A0-4443-8A7F-8FD831D79248 90410015514 Group:Training | Timepoint:4 weeks of training | Sex:Female raw_file=Motrpac_PASS1B_Gastroc_CoA_081320_a039.zip SUBJECT_SAMPLE_FACTORS 3D5BC47C-BB3D-45A2-8DB8-D7ADCD51997C 90412015514 Group:Training | Timepoint:4 weeks of training | Sex:Female raw_file=Motrpac_PASS1B_Gastroc_CoA_081320_a049.zip SUBJECT_SAMPLE_FACTORS 89D6F615-D17C-4EB9-88EB-A602940FF179 90416015514 Group:Training | Timepoint:4 weeks of training | Sex:Female raw_file=Motrpac_PASS1B_Gastroc_CoA_081320_a056.zip SUBJECT_SAMPLE_FACTORS FE012DC0-AF32-4C70-A4D4-F042B8BC4EC6 90420015514 Group:Training | Timepoint:4 weeks of training | Sex:Female raw_file=Motrpac_PASS1B_Gastroc_CoA_081320_a053.zip SUBJECT_SAMPLE_FACTORS 22D700B9-EDD0-4BC8-8155-EB9C39417F81 90280015514 Group:Training | Timepoint:4 weeks of training | Sex:Male raw_file=Motrpac_PASS1B_Gastroc_CoA_081320_a074.zip SUBJECT_SAMPLE_FACTORS 1CA4210C-3CE6-4A5A-996B-673EBDEB3B81 90281015514 Group:Training | Timepoint:4 weeks of training | Sex:Male raw_file=Motrpac_PASS1B_Gastroc_CoA_081320_a071.zip SUBJECT_SAMPLE_FACTORS 9F3E1040-D409-421E-B635-2572DC20ED89 90283015514 Group:Training | Timepoint:4 weeks of training | Sex:Male raw_file=Motrpac_PASS1B_Gastroc_CoA_081320_a025.zip SUBJECT_SAMPLE_FACTORS 569A9229-04E8-414A-A195-FE9E8F1B66AB 90289015514 Group:Training | Timepoint:4 weeks of training | Sex:Male raw_file=Motrpac_PASS1B_Gastroc_CoA_081320_a027.zip SUBJECT_SAMPLE_FACTORS E4271AF1-899A-4A65-9D8D-BF18CEE3F1CF 90292015514 Group:Training | Timepoint:4 weeks of training | Sex:Male raw_file=Motrpac_PASS1B_Gastroc_CoA_081320_a044.zip SUBJECT_SAMPLE_FACTORS 0D5071F5-D166-4CF1-BE8B-EB4DF6E04C0E 90251015514 Group:Training | Timepoint:8 weeks of training or control time | Sex:Female raw_file=Motrpac_PASS1B_Gastroc_CoA_081320_a054.zip SUBJECT_SAMPLE_FACTORS 2479BEE5-2A38-4D09-B15B-B1715F561A9F 90254015514 Group:Training | Timepoint:8 weeks of training or control time | Sex:Female raw_file=Motrpac_PASS1B_Gastroc_CoA_081320_a069.zip SUBJECT_SAMPLE_FACTORS 0A4A7935-3AF4-463F-84E3-DCF07671509D 90258015514 Group:Training | Timepoint:8 weeks of training or control time | Sex:Female raw_file=Motrpac_PASS1B_Gastroc_CoA_081320_a040.zip SUBJECT_SAMPLE_FACTORS 04C84D7E-FC8C-422F-AE4B-CAFADB63407B 90259015514 Group:Training | Timepoint:8 weeks of training or control time | Sex:Female raw_file=Motrpac_PASS1B_Gastroc_CoA_081320_a034.zip SUBJECT_SAMPLE_FACTORS 2B969165-1A52-43AA-8FD9-39AFA62F094F 90267015514 Group:Training | Timepoint:8 weeks of training or control time | Sex:Female raw_file=Motrpac_PASS1B_Gastroc_CoA_081320_a076.zip SUBJECT_SAMPLE_FACTORS 0BD282C7-7832-4581-9089-08A32D557034 90218015514 Group:Training | Timepoint:8 weeks of training or control time | Sex:Male raw_file=Motrpac_PASS1B_Gastroc_CoA_081320_a052.zip SUBJECT_SAMPLE_FACTORS 955498F4-70A0-4D50-A2BA-619A8FED8FEF 90222015514 Group:Training | Timepoint:8 weeks of training or control time | Sex:Male raw_file=Motrpac_PASS1B_Gastroc_CoA_081320_a072.zip SUBJECT_SAMPLE_FACTORS CFE06932-9314-4BCC-B2D9-73883D5FCDFB 90223015514 Group:Training | Timepoint:8 weeks of training or control time | Sex:Male raw_file=Motrpac_PASS1B_Gastroc_CoA_081320_a078.zip SUBJECT_SAMPLE_FACTORS 3719CB62-B551-49BE-94A0-E51DFE13D30D 90225015514 Group:Training | Timepoint:8 weeks of training or control time | Sex:Male raw_file=Motrpac_PASS1B_Gastroc_CoA_081320_a065.zip SUBJECT_SAMPLE_FACTORS F65955CE-E49F-48C7-B861-02A2FDF6F9B8 90227015514 Group:Training | Timepoint:8 weeks of training or control time | Sex:Male raw_file=Motrpac_PASS1B_Gastroc_CoA_081320_a050.zip #COLLECTION CO:SAMPLE_TYPE Gastrocnemius #TREATMENT TR:TREATMENT_SUMMARY - #SAMPLEPREP SP:SAMPLEPREP_SUMMARY 500 ul of tissue homogenate preprared at 50 mg/ml in 50% acetonitrile/0.3% SP:SAMPLEPREP_SUMMARY formic acid are spiked with C17 Acyl CoA. The acyl CoAs are purified by solid SP:SAMPLEPREP_SUMMARY phase extraction using 2-(2-pyridyl) ethyl functionalized Silica gel SP:SAMPLEPREP_SUMMARY (Sigma-Aldrich 54127-U). #CHROMATOGRAPHY CH:CHROMATOGRAPHY_SUMMARY 80% methanol/20% water containing 30 mM ammonium hydroxide is used as the mobile CH:CHROMATOGRAPHY_SUMMARY phase, the flow is 0.030 ml/min. CH:INSTRUMENT_NAME Waters Acquity UPLC CH:COLUMN_NAME No column CH:CHROMATOGRAPHY_TYPE Flow induction analysis #ANALYSIS AN:ANALYSIS_TYPE MS #MS MS:INSTRUMENT_NAME Waters Xevo TQ-S MS:INSTRUMENT_TYPE Triple quadrupole MS:MS_TYPE ESI MS:MS_COMMENTS Ion ratios of endogenous acyl CoAs to the C-17 CoA internal standard are MS:MS_COMMENTS computed from centroided spectra using a software package NeoLynx (Waters, MS:MS_COMMENTS Milford, MA). The ratios are converted to concentrations using calibrators MS:MS_COMMENTS prepared by spiking tissue homogenates with authentic CoAs (Sigma, St. Louis , MS:MS_COMMENTS MO) having saturated acyl chain lengths C0- C18. Corrections for the heavy MS:MS_COMMENTS isotope effects, mainly 13C, to the adjacent m+2 spectral peaks in a particular MS:MS_COMMENTS chain length cluster are made empirically by referring to the observed spectra MS:MS_COMMENTS for the analytical standards. The values are expressed in pmol/mg. Spectra are MS:MS_COMMENTS acquired in the multichannel acquisition mode monitoring the neutral loss of 507 MS:MS_COMMENTS amu (phosphoadenosine diphosphate) and scanning from m/z 750 to1060. MS:ION_MODE POSITIVE #MS_METABOLITE_DATA MS_METABOLITE_DATA:UNITS pmol/mg of tissue MS_METABOLITE_DATA_START Samples 90245015514 90248015514 90252015514 90265015514 90266015514 90217015514 90229015514 90232015514 90237015514 90239015514 80008815502_1 80008815502_2 80008815502_3 80008815502_4 80009825502_1 80009825502_2 80009825502_3 80009825502_4 90559015514 90560015514 90564015514 90567015514 90571015514 90421015514 90422015514 90423015514 90426015514 90430015514 90576015514 90578015514 90581015514 90585015514 90587015514 90439015514 90441015514 90444015514 90449015514 90450015514 90406015514 90410015514 90412015514 90416015514 90420015514 90280015514 90281015514 90283015514 90289015514 90292015514 90251015514 90254015514 90258015514 90259015514 90267015514 90218015514 90222015514 90223015514 90225015514 90227015514 Factors Group:Control | Timepoint:8 weeks of training or control time | Sex:Female Group:Control | Timepoint:8 weeks of training or control time | Sex:Female Group:Control | Timepoint:8 weeks of training or control time | Sex:Female Group:Control | Timepoint:8 weeks of training or control time | Sex:Female Group:Control | Timepoint:8 weeks of training or control time | Sex:Female Group:Control | Timepoint:8 weeks of training or control time | Sex:Male Group:Control | Timepoint:8 weeks of training or control time | Sex:Male Group:Control | Timepoint:8 weeks of training or control time | Sex:Male Group:Control | Timepoint:8 weeks of training or control time | Sex:Male Group:Control | Timepoint:8 weeks of training or control time | Sex:Male Group:QC-ExternalStandard | Timepoint:0 hour | Sex:- Group:QC-ExternalStandard | Timepoint:0 hour | Sex:- Group:QC-ExternalStandard | Timepoint:0 hour | Sex:- Group:QC-ExternalStandard | Timepoint:0 hour | Sex:- Group:QC-ExternalStandard | Timepoint:0 hour | Sex:- Group:QC-ExternalStandard | Timepoint:0 hour | Sex:- Group:QC-ExternalStandard | Timepoint:0 hour | Sex:- Group:QC-ExternalStandard | Timepoint:0 hour | Sex:- Group:Training | Timepoint:1 week of training or control time | Sex:Female Group:Training | Timepoint:1 week of training or control time | Sex:Female Group:Training | Timepoint:1 week of training or control time | Sex:Female Group:Training | Timepoint:1 week of training or control time | Sex:Female Group:Training | Timepoint:1 week of training or control time | Sex:Female Group:Training | Timepoint:1 week of training or control time | Sex:Male Group:Training | Timepoint:1 week of training or control time | Sex:Male Group:Training | Timepoint:1 week of training or control time | Sex:Male Group:Training | Timepoint:1 week of training or control time | Sex:Male Group:Training | Timepoint:1 week of training or control time | Sex:Male Group:Training | Timepoint:2 weeks of training | Sex:Female Group:Training | Timepoint:2 weeks of training | Sex:Female Group:Training | Timepoint:2 weeks of training | Sex:Female Group:Training | Timepoint:2 weeks of training | Sex:Female Group:Training | Timepoint:2 weeks of training | Sex:Female Group:Training | Timepoint:2 weeks of training | Sex:Male Group:Training | Timepoint:2 weeks of training | Sex:Male Group:Training | Timepoint:2 weeks of training | Sex:Male Group:Training | Timepoint:2 weeks of training | Sex:Male Group:Training | Timepoint:2 weeks of training | Sex:Male Group:Training | Timepoint:4 weeks of training | Sex:Female Group:Training | Timepoint:4 weeks of training | Sex:Female Group:Training | Timepoint:4 weeks of training | Sex:Female Group:Training | Timepoint:4 weeks of training | Sex:Female Group:Training | Timepoint:4 weeks of training | Sex:Female Group:Training | Timepoint:4 weeks of training | Sex:Male Group:Training | Timepoint:4 weeks of training | Sex:Male Group:Training | Timepoint:4 weeks of training | Sex:Male Group:Training | Timepoint:4 weeks of training | Sex:Male Group:Training | Timepoint:4 weeks of training | Sex:Male Group:Training | Timepoint:8 weeks of training or control time | Sex:Female Group:Training | Timepoint:8 weeks of training or control time | Sex:Female Group:Training | Timepoint:8 weeks of training or control time | Sex:Female Group:Training | Timepoint:8 weeks of training or control time | Sex:Female Group:Training | Timepoint:8 weeks of training or control time | Sex:Female Group:Training | Timepoint:8 weeks of training or control time | Sex:Male Group:Training | Timepoint:8 weeks of training or control time | Sex:Male Group:Training | Timepoint:8 weeks of training or control time | Sex:Male Group:Training | Timepoint:8 weeks of training or control time | Sex:Male Group:Training | Timepoint:8 weeks of training or control time | Sex:Male CoA(10:0) 0.0345 0.0344 0.0408 0.1489 0.0346 0.0494 0.0356 0.0450 0.0121 0.0572 0.0541 0.0656 0.0617 0.0355 0.0288 0.0298 0.0387 0.0745 0.0491 0.0341 0.0169 0.0254 0.0425 0.0302 0.0327 0.0337 0.0307 0.0390 0.0480 0.0265 0.0500 0.0197 0.0133 0.0237 0.0329 0.0452 0.0317 0.0366 0.0346 0.0274 0.0157 0.0406 0.0555 0.0319 0.0433 0.0452 0.0637 0.0815 0.0476 0.0399 0.0300 0.0261 0.0289 0.0461 CoA(10:1) 0.0022 0.0033 0.0063 0.0064 0.0010 0.0026 0.0052 0.0040 0.0170 0.0219 0.0127 0.0118 0.0059 0.0062 0.0100 0.0171 0.0035 0.0066 0.0062 0.0051 0.0056 0.0022 0.0051 0.0076 0.0106 0.0146 0.0118 0.0010 0.0025 0.0080 0.0038 0.0008 0.0036 0.0054 0.0026 0.0034 0.0007 0.0090 0.0157 0.0064 0.0039 0.0091 0.0066 0.0020 0.0078 0.0019 0.0038 0.0048 0.0021 0.0078 0.0066 0.0050 0.0063 CoA(10:2) 0.0053 0.0075 0.0040 0.0027 0.0040 0.0039 0.0011 0.0013 0.0052 0.0040 0.0091 0.0067 0.0021 0.0079 0.0048 0.0076 0.0022 0.0027 0.0052 0.0013 0.0053 0.0027 0.0112 0.0056 0.0024 0.0040 0.0010 0.0011 0.0027 0.0031 0.0022 0.0019 0.0053 0.0040 0.0010 0.0067 0.0067 0.0040 0.0040 0.0029 0.0010 0.0027 0.0008 0.0073 0.0027 0.0080 0.0027 0.0053 0.0053 0.0066 0.0021 0.0010 0.0039 0.0040 CoA(10:3) 0.0053 0.0013 0.0027 0.0013 0.0027 0.0067 0.0013 0.0053 0.0040 0.0053 0.0013 0.0093 0.0120 0.0027 0.0040 0.0027 0.0093 0.0053 0.0080 0.0013 0.0040 0.0120 0.0187 0.0053 0.0080 0.0013 0.0067 0.0040 0.0013 CoA(11:0) 0.0055 0.0066 0.0053 0.0083 0.0026 0.0024 0.0041 0.0080 0.0043 0.0042 0.0122 0.0080 0.0094 0.0055 0.0024 0.0049 0.0082 0.0043 0.0065 0.0042 0.0065 0.0002 0.0028 0.0037 0.0008 0.0039 0.0028 0.0039 0.0009 0.0001 0.0064 0.0029 0.0028 0.0039 0.0084 0.0035 0.0018 0.0001 0.0025 0.0040 0.0037 0.0054 0.0056 0.0002 0.0055 0.0028 0.0029 0.0070 0.0013 0.0014 0.0039 0.0041 0.0002 0.0043 0.0039 0.0041 CoA(11:1) 0.0022 0.0012 0.0016 0.0033 0.0013 0.0118 0.0001 0.0005 0.0007 0.0003 0.0028 0.0051 0.0027 0.0025 0.0037 0.0063 0.0017 0.0013 0.0047 0.0034 0.0020 0.0056 0.0093 0.0022 0.0007 0.0040 0.0004 0.0021 0.0016 0.0056 CoA(11:2) 0.0108 0.0203 0.0162 0.0243 0.0122 0.0081 0.0081 0.0149 0.0041 0.0176 0.0135 0.0095 0.0068 0.0108 0.0135 0.0135 0.0176 0.0095 0.0230 0.0149 0.0189 0.0162 0.0230 0.0095 0.0041 0.0054 0.0108 0.0135 0.0149 0.0216 0.0108 0.0068 0.0270 0.0068 0.0216 0.0324 0.0122 0.0311 0.0243 0.0203 0.0216 0.0149 0.0149 0.0270 0.0230 0.0149 0.0162 0.0203 0.0284 0.0392 0.0108 0.0068 0.0108 0.0243 0.0270 0.0122 0.0122 0.0176 CoA(12:0) 0.0089 0.0080 0.0171 0.1438 0.0096 0.0209 0.0104 0.0093 0.0018 0.0063 0.0325 0.0259 0.0280 0.0290 0.0157 0.0256 0.0157 0.0118 0.0317 0.0421 0.0071 0.0149 0.0132 0.0059 0.0094 0.0141 0.0158 0.0138 0.0129 0.0206 0.0310 0.0104 0.0122 0.0089 0.0132 0.0067 0.0149 0.0188 0.0059 0.0050 0.0083 0.0095 0.0211 0.0081 0.0151 0.0199 0.0531 0.0203 0.0184 0.0176 0.0224 0.0776 0.0098 0.0131 0.0067 0.0094 0.0260 0.0357 CoA(12:0-OH) 0.0018 0.0008 0.0048 0.0061 0.0020 0.0016 0.0046 0.0047 0.0007 0.0074 0.0007 0.0006 0.0036 0.0017 0.0007 0.0035 0.0033 0.0070 0.0014 0.0023 0.0048 0.0006 0.0018 0.0037 0.0037 0.0032 0.0014 0.0033 0.0018 CoA(12:1) 0.0069 0.0028 0.0078 0.0111 0.0055 0.0028 0.0096 0.0055 0.0180 0.0157 0.0083 0.0265 0.0082 0.0048 0.0081 0.0052 0.0275 0.0031 0.0118 0.0021 0.0055 0.0096 0.0017 0.0102 0.0071 0.0081 0.0137 0.0050 0.0056 0.0012 0.0077 0.0055 0.0018 0.0021 0.0035 0.0102 0.0055 0.0004 0.0082 0.0014 0.0064 0.0033 0.0026 0.0081 0.0023 0.0097 0.0049 0.0059 0.0018 0.0014 0.0131 CoA(12:2) 0.0336 0.0356 0.0520 0.0284 0.0418 0.0370 0.0285 0.0246 0.0149 0.0219 0.0164 0.0178 0.0574 0.0110 0.0353 0.0513 0.0256 0.0229 0.0123 0.0245 0.0310 0.0342 0.0133 0.0163 0.0205 0.0244 0.0366 0.0504 0.0378 0.0230 0.0255 0.0147 0.0178 0.0052 0.0231 0.0312 0.0452 0.0489 0.0504 0.0602 0.0397 0.0246 0.0192 0.0067 CoA(12:3) 0.0014 0.0068 0.0068 0.0164 0.0055 0.0041 0.0055 0.0068 0.0027 0.0014 0.0014 0.0027 0.0082 0.0014 0.0041 0.0041 0.0041 0.0014 0.0055 0.0055 0.0041 0.0014 0.0027 0.0027 0.0041 0.0027 0.0055 0.0027 0.0027 0.0055 0.0027 0.0041 0.0027 0.0014 0.0027 0.0041 0.0110 0.0178 0.0082 0.0014 CoA(13:0) 0.0102 0.0087 0.0073 0.0058 0.0073 0.0087 0.0044 0.0102 0.0087 0.0029 0.0219 0.0204 0.0131 0.0131 0.0102 0.0175 0.0087 0.0233 0.0087 0.0102 0.0073 0.0087 0.0073 0.0058 0.0131 0.0131 0.0073 0.0058 0.0117 0.0073 0.0160 0.0262 0.0160 0.0073 0.0087 0.0015 0.0131 0.0029 0.0102 0.0058 0.0058 0.0146 0.0044 0.0073 0.0073 0.0087 0.0102 0.0102 0.0044 0.0044 0.0102 0.0146 0.0073 0.0044 0.0087 0.0102 0.0087 CoA(14:0) 0.0488 0.0710 0.0908 0.1757 0.0582 0.0864 0.0550 0.0724 0.0951 0.0723 0.0889 0.0822 0.0873 0.0769 0.0861 0.0846 0.0752 0.0781 0.1373 0.0922 0.0587 0.0471 0.0742 0.0673 0.0904 0.0835 0.1007 0.1094 0.0961 0.0818 0.1104 0.0637 0.0588 0.1117 0.0733 0.0705 0.0691 0.0844 0.0659 0.0625 0.0610 0.0665 0.0966 0.0653 0.0593 0.1098 0.1107 0.1035 0.0973 0.0604 0.0989 0.1228 0.0709 0.0761 0.0535 0.1116 0.1114 0.1067 CoA(14:0-OH) 0.0019 0.0001 0.0015 0.0000 0.0016 0.0030 0.0010 0.0011 0.0011 0.0012 0.0016 0.0072 0.0006 0.0020 0.0019 0.0005 0.0039 0.0016 0.0048 0.0017 0.0118 0.0013 0.0050 0.0009 0.0019 0.0003 0.0028 0.0015 0.0002 0.0003 0.0005 0.0010 0.0002 0.0011 0.0030 0.0031 0.0013 0.0011 CoA(14:1) 0.0064 0.0230 0.0249 0.0188 0.0191 0.0440 0.0107 0.0208 0.0262 0.0076 0.0423 0.0465 0.0373 0.0411 0.0233 0.0391 0.0210 0.0278 0.0468 0.0143 0.0149 0.0090 0.0132 0.0078 0.0179 0.0136 0.0207 0.0168 0.0304 0.0364 0.0275 0.0085 0.0078 0.0105 0.0084 0.0096 0.0176 0.0031 0.0153 0.0109 0.0149 0.0116 0.0233 0.0234 0.0045 0.0136 0.0187 0.0136 0.0227 0.0100 0.0224 0.0118 0.0112 0.0143 0.0091 0.0110 0.0176 0.0285 CoA(14:2) 0.0140 0.0203 0.0327 0.0312 0.0125 0.0280 0.0187 0.0109 0.0187 0.0187 0.0623 0.0514 0.0499 0.0421 0.0327 0.0467 0.0405 0.0514 0.0639 0.0296 0.0234 0.0203 0.0249 0.0327 0.0078 0.0203 0.0280 0.0203 0.0405 0.0265 0.0218 0.0249 0.0327 0.0203 0.0265 0.0296 0.0280 0.0187 0.0327 0.0234 0.0249 0.0327 0.0343 0.0203 0.0203 0.0234 0.0421 0.0265 0.0234 0.0296 0.0296 0.0187 0.0156 0.0109 0.0280 CoA(15:0)_and_CoA(C14:1-OH) 0.0169 0.0134 0.0153 0.0170 0.0166 0.0159 0.0203 0.0119 0.0184 0.0237 0.0218 0.0302 0.0230 0.0220 0.0220 0.0203 0.0166 0.0231 0.0272 0.0169 0.0218 0.0099 0.0119 0.0133 0.0236 0.0286 0.0288 0.0311 0.0248 0.0166 0.0322 0.0153 0.0170 0.0237 0.0234 0.0198 0.0130 0.0218 0.0068 0.0129 0.0169 0.0134 0.0202 0.0170 0.0198 0.0146 0.0216 0.0233 0.0303 0.0119 0.0232 0.0149 0.0170 0.0218 0.0184 0.0166 0.0194 0.0218 CoA(15:1) 0.0014 0.0027 0.0095 0.0015 0.0017 0.0017 0.0064 0.0027 0.0057 0.0012 0.0022 0.0017 0.0007 0.0098 0.0057 0.0029 0.0025 0.0042 0.0047 0.0019 0.0062 0.0014 0.0010 0.0044 0.0064 0.0032 0.0032 0.0008 0.0041 0.0027 0.0010 0.0014 0.0032 0.0083 0.0014 CoA(15:2) 0.0034 0.0068 0.0084 0.0068 0.0068 0.0068 0.0034 0.0017 0.0034 0.0034 0.0034 0.0017 0.0017 0.0068 0.0101 0.0135 0.0017 0.0051 0.0118 0.0101 0.0101 0.0068 0.0034 0.0101 0.0051 0.0084 0.0101 0.0101 0.0051 0.0084 0.0084 0.0034 0.0152 0.0084 0.0051 0.0051 0.0034 0.0068 0.0084 0.0068 0.0034 0.0017 0.0017 0.0084 0.0034 0.0101 0.0068 0.0118 0.0068 0.0034 0.0017 0.0017 0.0034 CoA(16:0) 0.4603 0.7386 0.6376 0.5404 0.3422 0.7454 0.7308 0.7452 0.8070 0.9224 0.5808 0.5517 0.5550 0.5116 0.7268 0.7175 0.6684 0.6775 0.9925 0.7092 0.6534 0.4689 0.8523 0.8592 1.0224 1.0497 1.0508 1.1215 0.6203 0.6696 0.8750 0.7307 0.6053 1.2110 0.8506 0.8970 0.6117 0.9247 0.6618 0.5429 0.4508 0.7039 0.7584 0.7474 0.5760 1.1252 1.0760 1.3723 0.9347 0.7578 0.6654 0.5871 0.5078 1.0451 0.6218 1.3934 1.3928 1.0343 CoA(16:1) 0.0707 0.1245 0.1321 0.0848 0.0822 0.1124 0.1274 0.1139 0.1447 0.1234 0.1256 0.1556 0.1416 0.1303 0.1666 0.1488 0.1395 0.1410 0.1811 0.1210 0.1045 0.0946 0.1187 0.1425 0.1609 0.1480 0.1734 0.1891 0.1558 0.0911 0.1505 0.1109 0.0857 0.1850 0.1176 0.1358 0.1137 0.1369 0.1129 0.0967 0.0907 0.1191 0.1298 0.1110 0.0818 0.1716 0.1629 0.2399 0.1477 0.1183 0.1328 0.0822 0.0957 0.1389 0.0698 0.1608 0.1847 0.1528 CoA(16:2) 0.0165 0.0165 0.0326 0.0234 0.0130 0.0432 0.0235 0.0291 0.0365 0.0091 0.0772 0.0567 0.0664 0.0862 0.0401 0.0326 0.0322 0.0360 0.0428 0.0145 0.0126 0.0184 0.0182 0.0219 0.0230 0.0217 0.0456 0.0376 0.0369 0.0161 0.0337 0.0219 0.0141 0.0234 0.0107 0.0145 0.0310 0.0223 0.0202 0.0159 0.0200 0.0145 0.0363 0.0215 0.0161 0.0271 0.0219 0.0306 0.0254 0.0219 0.0256 0.0130 0.0252 0.0200 0.0068 0.0235 0.0440 0.0291 CoA(16:3) 0.0019 0.0019 0.0074 0.0074 0.0130 0.0056 0.0056 0.0056 0.0019 0.0074 0.0074 0.0037 0.0093 0.0074 0.0074 0.0111 0.0111 0.0167 0.0037 0.0037 0.0019 0.0037 0.0037 0.0111 0.0056 0.0074 0.0130 0.0019 0.0056 0.0148 0.0037 0.0074 0.0074 0.0037 0.0037 0.0056 0.0019 0.0074 0.0037 0.0037 0.0074 0.0074 0.0056 0.0074 0.0037 0.0093 0.0056 0.0037 0.0037 0.0074 0.0037 0.0056 0.0056 0.0056 0.0056 CoA(17:1) 0.0482 0.0594 0.0445 0.0390 0.0482 0.0334 0.0445 0.0501 0.0501 0.0594 0.0612 0.0724 0.0575 0.0779 0.0612 0.0445 0.0501 0.0482 0.0390 0.0464 0.0427 0.0482 0.0408 0.0297 0.0631 0.0501 0.0445 0.0594 0.0408 0.0353 0.0408 0.0594 0.0371 0.0538 0.0501 0.0538 0.0371 0.0427 0.0371 0.0371 0.0390 0.0371 0.0501 0.0482 0.0408 0.0464 0.0353 0.0612 0.0482 0.0427 0.0482 0.0427 0.0390 0.0427 0.0353 0.0445 0.0501 0.0575 CoA(18:0) 0.3273 0.6249 0.6051 0.5311 0.3129 0.6481 0.3902 0.3915 0.5740 0.5151 0.3146 0.2595 0.2805 0.2857 0.4619 0.3620 0.3529 0.3542 0.6134 0.7088 0.5190 0.3962 0.5553 0.4939 0.7102 0.5062 0.5542 0.5725 0.4193 0.7620 0.7929 0.4760 0.5195 0.6232 0.5165 0.4324 0.4443 0.4515 0.5017 0.5349 0.3650 0.5778 0.6827 0.5603 0.3794 0.6712 0.6185 0.7852 0.7581 0.6147 0.7165 0.5706 0.4670 0.6733 0.4822 0.6985 0.8921 0.7126 CoA(18:1) 0.7221 0.7755 0.8803 0.8296 0.6617 0.7926 1.3733 1.3230 1.1653 1.1871 1.1646 1.1713 1.2466 1.1226 1.5221 1.5553 1.5236 1.5503 1.2643 0.9271 0.8830 0.7803 1.1255 1.0167 1.2592 1.2115 1.2506 1.5435 0.9140 0.7456 1.0194 1.1622 0.7818 1.5588 1.2124 1.0822 0.8577 1.2718 0.9071 0.8141 0.8176 0.8045 0.8977 0.9643 0.6276 1.3295 1.1983 1.6081 0.9740 1.0604 0.8752 0.8130 0.7643 1.5788 0.7406 1.6353 1.6255 1.1990 CoA(18:2) 0.4211 0.4688 0.4860 0.4328 0.3993 0.4267 1.0318 0.9167 0.7892 0.7428 1.0455 1.0613 1.0415 1.1043 1.1062 1.0897 1.0729 1.0780 0.6302 0.5755 0.4421 0.4821 0.5983 0.5979 0.7923 0.8653 0.6984 0.9102 0.5421 0.3782 0.5349 0.8760 0.5456 0.9618 0.5111 0.6109 0.5781 0.5997 0.5281 0.4986 0.5235 0.4714 0.6334 0.6751 0.4623 1.0111 0.7560 1.0851 0.6060 0.5421 0.5909 0.5665 0.4949 0.9127 0.3277 0.9120 1.0983 0.9220 CoA(18:3) 0.0335 0.0377 0.0335 0.0419 0.0419 0.0398 0.0565 0.0565 0.0544 0.0586 0.0649 0.0544 0.0628 0.0628 0.0649 0.0628 0.0628 0.0544 0.0544 0.0377 0.0335 0.0314 0.0398 0.0439 0.0460 0.0670 0.0628 0.0586 0.0377 0.0439 0.0460 0.0460 0.0439 0.0649 0.0335 0.0398 0.0523 0.0460 0.0314 0.0335 0.0356 0.0335 0.0439 0.0460 0.0398 0.0732 0.0523 0.0858 0.0460 0.0377 0.0502 0.0439 0.0481 0.0356 0.0272 0.0607 0.0607 0.0649 CoA(19:0) 0.0371 0.0520 0.0395 0.0412 0.0305 0.0605 0.0454 0.0329 0.0301 0.0498 0.0387 0.0369 0.0430 0.0425 0.0518 0.0408 0.0400 0.0492 0.0590 0.0537 0.0432 0.0483 0.0429 0.0452 0.0429 0.0405 0.0353 0.0542 0.0547 0.0596 0.0701 0.0419 0.0410 0.0400 0.0475 0.0344 0.0609 0.0410 0.0564 0.0450 0.0473 0.0497 0.0551 0.0465 0.0533 0.0404 0.0344 0.0486 0.0411 0.0514 0.0464 0.0597 0.0431 0.0473 0.0428 0.0340 0.0528 0.0503 CoA(19:1) 0.0047 0.0196 0.0019 0.0050 0.0075 0.0190 0.0052 0.0048 0.0104 0.0036 0.0090 0.0066 0.0077 0.0116 0.0041 0.0085 0.0152 0.0080 0.0134 0.0057 0.0062 0.0155 0.0088 0.0069 0.0083 0.0109 0.0195 0.0191 0.0146 0.0092 0.0254 0.0067 0.0153 0.0052 0.0093 0.0157 0.0070 0.0008 0.0087 0.0071 0.0046 0.0118 0.0133 0.0089 0.0118 0.0097 0.0131 0.0065 0.0078 0.0139 0.0084 0.0071 0.0072 0.0093 0.0131 0.0128 0.0164 CoA(19:2) 0.0132 0.0012 0.0004 0.0045 0.0124 0.0142 0.0054 0.0082 0.0004 0.0032 0.0048 0.0009 0.0004 0.0002 0.0028 0.0119 0.0061 0.0064 0.0059 0.0065 0.0093 0.0030 CoA(19:3) 0.0460 0.0502 0.0419 0.0565 0.0795 0.0774 0.0649 0.0439 0.0314 0.0314 0.0188 0.0377 0.0419 0.0356 0.0314 0.0272 0.0398 0.0251 0.0586 0.0293 0.0439 0.0586 0.0628 0.0398 0.0314 0.0293 0.0419 0.0335 0.0670 0.0586 0.0398 0.0460 0.0293 0.0398 0.0711 0.0649 0.0732 0.0460 0.0544 0.0377 0.0565 0.0272 0.0356 0.0523 0.0335 0.0502 0.0377 0.0398 0.0460 0.1046 0.0670 0.0691 0.0586 0.0607 0.0439 0.0356 0.0314 0.0272 CoA(2:0) 0.4065 0.5427 0.4564 0.4678 0.3451 0.8878 0.4405 0.4019 0.3747 0.2657 0.6085 0.6426 0.6699 0.6699 0.4768 0.5313 0.4768 0.5200 0.5699 0.3497 0.4859 0.5927 0.5245 0.3474 0.5018 0.5722 0.3111 0.4973 0.5722 0.7766 1.0468 0.5699 0.6812 0.7198 0.8175 0.4791 0.3293 0.4768 0.2657 0.3542 0.2907 0.4110 0.7153 0.2452 0.4905 0.5881 0.4451 0.3656 0.6176 0.3202 0.5858 0.4201 0.4337 0.4723 0.4678 0.4110 0.5177 0.7743 CoA(20:0) 0.0446 0.0287 0.0543 0.0561 0.0372 0.0453 0.0417 0.0264 0.0393 0.0375 0.0299 0.0374 0.0414 0.0271 0.0545 0.0448 0.0721 0.0577 0.0565 0.0411 0.0548 0.0671 0.0619 0.0417 0.1071 0.0505 0.0411 0.0342 0.0574 0.0568 0.0587 0.0561 0.0507 0.0532 0.0375 0.0562 0.0297 0.0433 0.0352 0.0527 0.0422 0.0393 0.0509 0.0482 0.0425 0.0485 0.0349 0.0524 0.0530 0.0625 0.0576 0.0441 0.0491 0.0434 0.0326 0.0652 0.0422 0.0591 CoA(20:1) 0.0413 0.0511 0.0472 0.0341 0.0343 0.0984 0.0632 0.0522 0.0496 0.0636 0.0268 0.0326 0.0186 0.0321 0.0303 0.0249 0.0396 0.0374 0.0931 0.0675 0.0588 0.0456 0.0684 0.0787 0.0748 0.0909 0.0523 0.0724 0.0712 0.0910 0.1231 0.0652 0.0736 0.0866 0.1098 0.0645 0.0593 0.0665 0.0490 0.0743 0.0284 0.0961 0.0728 0.0773 0.0572 0.0904 0.0978 0.1076 0.0876 0.0640 0.0690 0.0609 0.0551 0.1124 0.0533 0.0909 0.0908 0.0740 CoA(20:2) 0.0196 0.0246 0.0222 0.0264 0.0092 0.0309 0.0278 0.0319 0.0356 0.0407 0.0341 0.0375 0.0328 0.0239 0.0482 0.0322 0.0327 0.0386 0.0272 0.0293 0.0190 0.0357 0.0369 0.0349 0.0394 0.0309 0.0376 0.0308 0.0233 0.0336 0.0286 0.0402 0.0394 0.0337 0.0255 0.0347 0.0242 0.0229 0.0219 0.0324 0.0186 0.0321 0.0262 0.0432 0.0507 0.0556 0.0329 0.0371 0.0314 0.0297 0.0260 0.0512 0.0238 0.0401 0.0407 0.0255 CoA(20:3) 0.0252 0.0195 0.0370 0.0212 0.0245 0.0191 0.0267 0.0275 0.0306 0.0240 0.0106 0.0168 0.0052 0.0394 0.0403 0.0308 0.0246 0.0215 0.0240 0.0314 0.0152 0.0146 0.0302 0.0210 0.0362 0.0178 0.0189 0.0317 0.0202 0.0291 0.0300 0.0359 0.0200 0.0432 0.0180 0.0293 0.0126 0.0219 0.0222 0.0161 0.0236 0.0234 0.0173 0.0258 0.0233 0.0211 0.0275 0.0377 0.0196 0.0194 0.0309 0.0283 0.0241 0.0239 0.0097 0.0288 0.0397 0.0278 CoA(20:4) 0.1695 0.1653 0.1758 0.1841 0.1904 0.1528 0.2365 0.2148 0.2386 0.2406 0.2469 0.2323 0.2406 0.2197 0.2595 0.2679 0.2825 0.3055 0.2720 0.1862 0.2281 0.2176 0.2720 0.2163 0.3056 0.2867 0.2323 0.2616 0.2072 0.2030 0.2427 0.3076 0.2239 0.2532 0.1611 0.2323 0.2009 0.1946 0.2386 0.1904 0.1507 0.1988 0.2595 0.1967 0.1841 0.2930 0.2151 0.2940 0.1800 0.2281 0.2051 0.1779 0.1779 0.2260 0.0984 0.2825 0.3411 0.3055 CoA(20:5) 0.0209 0.0565 0.0146 0.0188 0.1004 CoA(2:0-COOH)_and_CoA(4:0-OH) 0.0503 0.0402 0.0244 0.0287 0.0216 0.0316 0.0273 0.0431 0.0316 0.0230 0.0287 0.0244 0.0216 0.0331 0.0201 0.0158 0.0316 0.0187 0.0287 0.0287 0.0374 0.0446 0.0431 0.0359 0.0474 0.0345 0.0273 0.0474 0.0216 0.0359 0.0417 0.0259 0.0302 0.0489 0.0431 0.0302 0.0316 0.0359 0.0187 0.0144 0.0201 0.0431 0.0230 0.0144 0.0345 0.0446 0.0388 0.0287 0.0345 0.0230 0.0230 0.0302 0.0201 0.0388 0.0302 0.0474 0.0417 0.0374 CoA(21:0) 0.0084 0.0084 0.0042 0.0042 0.0033 0.0063 0.0021 0.0042 0.0033 0.0125 0.0064 0.0021 0.0105 0.0105 0.0042 0.0084 0.0064 0.0084 0.0102 0.0126 0.0057 0.0063 0.0042 0.0050 0.0084 0.0084 0.0063 0.0008 0.0053 0.0042 0.0063 0.0042 0.0057 0.0063 0.0042 0.0057 0.0042 0.0063 0.0042 0.0084 0.0042 0.0105 0.0060 0.0037 0.0084 0.0064 0.0105 0.0021 CoA(21:1) 0.0001 0.0063 0.0063 0.0000 0.0042 0.0021 0.0042 0.0084 0.0085 0.0063 0.0039 0.0042 0.0000 0.0126 0.0018 0.0036 CoA(21:2) 0.0021 0.0063 0.0042 0.0018 0.0021 0.0018 0.0021 0.0042 0.0042 0.0021 CoA(21:3) 0.0042 0.0021 0.0021 0.0042 0.0021 0.0021 CoA(22:1) 0.0042 0.0233 0.0106 0.0083 0.0228 0.0148 0.0104 0.0001 0.0167 0.0083 0.0041 0.0056 0.0105 0.0167 0.0209 0.0147 0.0105 0.0252 0.0140 0.0147 0.0335 0.0314 0.0185 0.0271 0.0104 0.0042 0.0394 0.0228 0.0246 0.0145 0.0209 0.0147 0.0001 0.0126 0.0102 0.0081 0.0104 0.0081 0.0063 0.0105 0.0186 0.0084 0.0167 0.0189 0.0104 0.0244 0.0252 0.0161 0.0189 0.0078 0.0125 0.0126 0.0104 0.0105 0.0116 CoA(22:2) 0.0105 0.0001 0.0020 0.0001 0.0000 0.0001 0.0042 0.0000 0.0000 0.0042 0.0021 0.0000 0.0000 0.0063 0.0021 0.0020 0.0041 0.0001 0.0000 0.0000 0.0020 0.0021 0.0000 0.0021 0.0020 0.0000 0.0000 0.0001 0.0042 0.0042 0.0041 0.0001 0.0001 0.0063 CoA(22:3) 0.0025 0.0109 0.0057 0.0032 0.0063 0.0053 0.0002 0.0034 0.0046 0.0011 0.0019 0.0014 0.0027 0.0014 0.0012 0.0029 0.0064 0.0030 0.0011 0.0068 0.0027 0.0030 0.0016 0.0003 0.0020 0.0019 0.0055 0.0025 0.0025 0.0030 0.0028 0.0032 0.0030 0.0010 CoA(22:4) 0.0144 0.0113 0.0112 0.0178 0.0230 0.0210 0.0142 0.0290 0.0210 0.0267 0.0225 0.0256 0.0266 0.0198 0.0291 0.0169 0.0256 0.0207 0.0294 0.0205 0.0185 0.0243 0.0186 0.0203 0.0334 0.0238 0.0228 0.0287 0.0240 0.0277 0.0220 0.0327 0.0203 0.0350 0.0392 0.0241 0.0156 0.0361 0.0313 0.0222 0.0262 0.0286 0.0155 0.0193 0.0045 0.0187 0.0256 0.0438 0.0195 0.0252 0.0116 0.0221 0.0238 0.0280 0.0208 0.0406 0.0366 0.0215 CoA(22:5) 0.0444 0.0366 0.0515 0.0637 0.0564 0.0422 0.0737 0.0584 0.0704 0.0739 0.1028 0.0959 0.0750 0.1068 0.0863 0.0837 0.0956 0.1003 0.0421 0.0454 0.0446 0.0480 0.0582 0.0611 0.0427 0.0515 0.0722 0.0605 0.0500 0.0393 0.0494 0.0618 0.0322 0.0885 0.0462 0.0490 0.0500 0.0528 0.0712 0.0624 0.0636 0.0332 0.0370 0.0674 0.0544 0.0573 0.0533 0.0861 0.0380 0.0560 0.0632 0.0627 0.0513 0.0652 0.0432 0.0650 0.0778 0.0670 CoA(22:6) 0.0816 0.0636 0.0762 0.1208 0.0852 0.0686 0.1100 0.1001 0.1040 0.1088 0.1962 0.1865 0.1716 0.1832 0.1524 0.1554 0.1742 0.1563 0.1118 0.0753 0.0660 0.0859 0.1013 0.0822 0.1216 0.1184 0.1204 0.1145 0.1143 0.0741 0.0762 0.1339 0.0932 0.1233 0.0976 0.0789 0.0723 0.0956 0.1130 0.1017 0.1079 0.1151 0.0894 0.1101 0.0852 0.1079 0.1208 0.1536 0.0684 0.0884 0.0819 0.0996 0.0774 0.1250 0.0615 0.1267 0.1387 0.1127 CoA(3:0) 0.0399 0.0642 0.0625 0.1337 0.0486 0.0590 0.0521 0.0590 0.0538 0.0278 0.0312 0.0503 0.0399 0.0365 0.0278 0.0382 0.0208 0.0156 0.0677 0.0417 0.0417 0.0555 0.0312 0.0330 0.0781 0.0503 0.0295 0.0365 0.0365 0.0469 0.0469 0.0365 0.0243 0.0469 0.0382 0.0382 0.0486 0.0608 0.0555 0.0434 0.0382 0.0382 0.0382 0.0278 0.0590 0.0746 0.0417 0.0469 0.0625 0.1041 0.1041 0.0642 0.0555 0.0417 0.0365 0.0260 0.0555 CoA(3:0_ 3-OH) 0.0088 0.0117 0.0176 0.0279 0.0147 0.0132 0.0220 0.0044 0.0235 0.0044 0.0059 0.0103 0.0088 0.0029 0.0191 0.0162 0.0191 0.0088 0.0117 0.0308 0.0176 0.0059 0.0206 0.0147 0.0044 0.0176 0.0162 0.0044 0.0220 0.0191 0.0088 0.0117 0.0088 0.0088 0.0147 0.0088 0.0059 0.0206 0.0147 0.0308 0.0323 0.0206 0.0323 0.0191 0.0176 0.0176 0.0250 0.0117 CoA(3:0-COOH) 0.1902 0.1263 0.1508 0.1304 0.0964 0.0448 0.1317 0.1684 0.4740 0.1779 0.5732 0.4632 0.4713 0.4740 0.2703 0.2418 0.1874 0.1779 0.1222 0.1834 0.1059 0.1671 0.1643 0.1073 0.3545 0.2635 0.3491 0.3844 0.1671 0.0489 0.0883 0.3409 0.1385 0.2187 0.0747 0.1005 0.1127 0.0801 0.1480 0.1440 0.1480 0.1372 0.3260 0.1290 0.1059 0.1684 0.1616 0.2024 0.1480 0.1413 0.1942 0.1929 0.1426 0.1508 0.0421 0.1657 0.2554 0.3233 CoA(4:0) 0.0073 0.0176 0.0558 0.1953 0.0793 0.0896 0.1160 0.0059 0.0147 0.0088 0.0220 0.0176 0.0162 0.0147 0.0088 0.0132 0.0073 0.0176 0.1894 0.0308 0.0587 0.1101 0.1233 0.0117 0.0088 0.0073 0.0073 0.0103 0.1277 0.0573 0.0294 0.0088 0.0117 0.0103 0.1527 0.1116 0.0852 0.1909 0.0705 0.0132 0.0073 0.0103 0.0059 0.0631 0.0485 0.0440 0.0485 0.0073 0.1806 0.1615 0.1571 0.2261 0.1571 0.1131 0.0073 0.0162 0.0132 0.0162 CoA(4:0-CH3) 0.0086 0.0115 0.0187 0.1150 0.0144 0.0172 0.0287 0.0086 0.0101 0.0029 0.0101 0.0101 0.0072 0.0144 0.0043 0.0043 0.0029 0.0101 0.0402 0.0359 0.0129 0.0230 0.0273 0.0115 0.0158 0.0043 0.0072 0.0057 0.0216 0.0187 0.0201 0.0115 0.0029 0.0101 0.0259 0.0273 0.0129 0.0287 0.0101 0.0057 0.0072 0.0086 0.0057 0.0115 0.0172 0.0230 0.0417 0.0086 0.0259 0.0331 0.0446 0.0891 0.0345 0.0287 0.0029 0.0043 0.0057 CoA(4:0-COOH) 0.0026 0.0026 0.0013 0.0013 0.0026 0.0026 0.0013 0.0026 0.0038 0.0013 0.0013 0.0064 0.0013 0.0026 0.0026 0.0013 0.0013 0.0051 0.0038 0.0038 0.0013 0.0051 0.0026 0.0026 0.0026 0.0038 0.0013 0.0013 0.0038 0.0026 0.0026 0.0026 0.0026 0.0013 0.0026 CoA(4:1) 0.0059 0.0176 0.0162 0.0103 0.0132 0.0191 0.0147 0.0162 0.0073 0.0176 0.0176 0.0162 0.0132 0.0117 0.0132 0.0117 0.0147 0.0147 0.0162 0.0088 0.0132 0.0073 0.0191 0.0147 0.0191 0.0132 0.0206 0.0103 0.0103 0.0147 0.0162 0.0191 0.0117 0.0132 0.0103 0.0117 0.0073 0.0132 0.0073 0.0132 0.0059 0.0117 0.0088 0.0117 0.0059 0.0059 0.0103 0.0147 0.0117 0.0162 0.0117 0.0132 0.0117 0.0088 0.0132 CoA(4:1-CH3) 0.0029 0.0129 0.0101 0.0359 0.0302 0.0287 0.0446 0.0072 0.0072 0.0115 0.0158 0.0129 0.0144 0.0115 0.0072 0.0115 0.0489 0.0029 0.0302 0.0517 0.0560 0.0057 0.0043 0.0359 0.0287 0.0072 0.0014 0.0029 0.0057 0.0417 0.0359 0.0331 0.0575 0.0230 0.0057 0.0158 0.0072 0.0029 0.0172 0.0187 0.0230 0.0029 0.0632 0.0460 0.0532 0.0575 0.0575 0.0517 0.0086 0.0043 0.0129 0.0043 CoA(4:1-COOH) 0.0013 0.0013 0.0026 0.0013 0.0038 0.0051 0.0026 0.0026 0.0013 0.0026 0.0013 0.0026 0.0026 0.0038 0.0013 0.0038 0.0013 0.0013 0.0038 0.0026 0.0013 0.0026 0.0013 0.0013 0.0026 0.0038 0.0013 0.0051 0.0013 0.0051 0.0013 0.0013 0.0013 0.0115 0.0064 0.0013 0.0026 CoA(6:0) 0.0163 0.0326 0.0326 0.1195 0.0489 0.0231 0.0407 0.0190 0.0258 0.0258 0.0503 0.0380 0.0421 0.0557 0.0503 0.0367 0.0312 0.0448 0.0666 0.0530 0.0258 0.0435 0.0407 0.0217 0.0244 0.0244 0.0258 0.0149 0.0312 0.0326 0.0394 0.0380 0.0204 0.0475 0.0394 0.0204 0.0475 0.0244 0.0149 0.0217 0.0407 0.0340 0.0258 0.0312 0.0761 0.0136 0.0448 0.0462 0.0774 0.0937 0.0475 0.0394 0.0177 0.0149 0.0204 0.0312 CoA(6:1) 0.0014 0.0054 0.0027 0.0054 0.0014 0.0041 0.0027 0.0041 0.0027 0.0068 0.0054 0.0054 0.0041 0.0027 0.0041 0.0054 0.0054 0.0014 0.0014 0.0081 0.0027 0.0027 0.0109 0.0041 0.0054 0.0027 0.0027 0.0054 0.0027 0.0027 0.0014 0.0041 0.0041 0.0027 0.0014 0.0027 0.0014 0.0014 0.0081 0.0014 0.0014 0.0014 0.0054 0.0027 0.0014 0.0014 0.0014 0.0014 CoA(8:0) 0.0035 0.0110 0.0225 0.1214 0.0128 0.0121 0.0077 0.0122 0.0114 0.0075 0.0343 0.0228 0.0290 0.0189 0.0125 0.0101 0.0074 0.0125 0.0490 0.0486 0.0075 0.0165 0.0176 0.0098 0.0226 0.0028 0.0077 0.0074 0.0160 0.0111 0.0230 0.0048 0.0075 0.0060 0.0076 0.0163 0.0124 0.0072 0.0062 0.0037 0.0141 0.0131 0.0140 0.0100 0.0099 0.0510 0.0101 0.0127 0.0378 0.0535 0.0154 0.0059 0.0037 0.0113 0.0061 0.0187 CoA(8:1) 0.0051 0.0077 0.0077 0.0064 0.0103 0.0090 0.0026 0.0026 0.0051 0.0038 0.0064 0.0051 0.0051 0.0026 0.0038 0.0051 0.0141 0.0026 0.0026 0.0026 0.0051 0.0064 0.0064 0.0141 0.0038 0.0090 0.0064 0.0013 0.0051 0.0026 0.0026 0.0051 0.0013 0.0051 0.0064 0.0064 0.0026 0.0026 0.0141 0.0013 0.0038 0.0051 0.0038 0.0090 0.0026 0.0013 0.0090 0.0051 0.0064 0.0026 0.0038 0.0038 0.0077 CoA(9:0) 0.0141 0.0195 0.0076 0.0092 0.0157 0.0129 0.0298 0.0181 0.0128 0.0083 0.0194 0.0089 0.0118 0.0063 0.0124 0.0023 0.0116 0.0104 0.0118 0.0117 0.0115 0.0479 0.0089 0.0124 0.0092 0.0062 0.0091 0.0154 0.0062 0.0117 0.0064 0.0038 0.0073 0.0092 0.0101 0.0218 0.0181 0.0076 0.0208 0.0192 0.0118 0.0141 0.0039 0.0077 0.0105 0.0261 0.0155 0.0077 0.0072 0.0208 CoA(9:1) 0.0039 0.0013 0.0026 0.0052 0.0026 0.0026 0.0039 0.0026 0.0039 0.0105 0.0026 0.0065 0.0026 0.0026 0.0079 0.0039 0.0026 0.0013 0.0013 0.0039 0.0065 0.0026 0.0079 0.0039 0.0013 0.0039 0.0039 0.0013 0.0039 0.0039 0.0013 0.0013 0.0065 0.0039 0.0052 0.0026 0.0039 0.0026 0.0013 0.0052 0.0026 0.0039 0.0013 0.0013 0.0026 0.0013 0.0079 0.0013 coenzyme A 5.3455 5.9847 5.8441 6.3533 5.1453 5.1985 6.4918 5.7823 7.3504 5.3157 6.4364 6.2766 6.0997 6.5642 5.6353 5.9847 6.2233 5.6971 8.2047 6.1423 5.8952 6.3639 7.2438 5.9868 7.5911 8.5605 7.1267 8.0726 7.1245 5.8398 6.3085 6.5663 5.6246 8.0875 7.7403 6.7176 5.5394 7.8383 6.7986 5.6033 5.4244 6.1125 7.9107 6.4044 6.2638 7.2417 6.3682 7.0649 8.0385 6.6942 7.7552 7.8319 7.4548 6.9392 4.7618 7.1032 6.9072 8.0044 MS_METABOLITE_DATA_END #METABOLITES METABOLITES_START metabolite_name pubchem_id inchi_key kegg_id other_id other_id_type ri ri_type moverz_quant CoA(10:0) CoA(10:1) CoA(10:2) CoA(10:3) CoA(11:0) CoA(11:1) CoA(11:2) CoA(12:0) CoA(12:0-OH) CoA(12:1) CoA(12:2) CoA(12:3) CoA(13:0) CoA(14:0) CoA(14:0-OH) CoA(14:1) CoA(14:2) CoA(15:0)_and_CoA(C14:1-OH) CoA(15:1) CoA(15:2) CoA(16:0) CoA(16:1) CoA(16:2) CoA(16:3) CoA(17:1) CoA(18:0) CoA(18:1) CoA(18:2) CoA(18:3) CoA(19:0) CoA(19:1) CoA(19:2) CoA(19:3) CoA(2:0) CoA(20:0) CoA(20:1) CoA(20:2) CoA(20:3) CoA(20:4) CoA(20:5) CoA(2:0-COOH)_and_CoA(4:0-OH) CoA(21:0) CoA(21:1) CoA(21:2) CoA(21:3) CoA(22:1) CoA(22:2) CoA(22:3) CoA(22:4) CoA(22:5) CoA(22:6) CoA(3:0) CoA(3:0, 3-OH) CoA(3:0-COOH) CoA(4:0) CoA(4:0-CH3) CoA(4:0-COOH) CoA(4:1) CoA(4:1-CH3) CoA(4:1-COOH) CoA(6:0) CoA(6:1) CoA(8:0) CoA(8:1) CoA(9:0) CoA(9:1) coenzyme A METABOLITES_END #END