{
"METABOLOMICS WORKBENCH":{"STUDY_ID":"ST001206","ANALYSIS_ID":"AN002008","VERSION":"1","CREATED_ON":"July 1, 2019, 12:05 pm"},

"PROJECT":{"PROJECT_TITLE":"12-LOX metabolites in cold adaptation","PROJECT_SUMMARY":"The goal of this project is to understand the role of the enzyme 12-lipoxygenase in the adaptive thermogenesis. We found this enzyme is activated by cold stimulation, then producing lipid metabolites in adipose tissue and releasing them into the circulation to regulate fuel utilisation and thermogenic pathways required for the cold adaptation.","INSTITUTE":"Joslin Diabetes Center - Harvard medical School","DEPARTMENT":"Integrative Physiology and Metabolism","LABORATORY":"Yu-Hua Tseng lab","LAST_NAME":"Leiria","FIRST_NAME":"Luiz","ADDRESS":"One Joslin Place, Boston, MA-USA, 02215","EMAIL":"luiz.leiri@joslin.harvard.edu","PHONE":"1 6173091967"},

"STUDY":{"STUDY_TITLE":"Effects of cold exposure on serum lipidomic in mice","STUDY_SUMMARY":"We aimed to identify lipids released during cold exposure from adipose tissue, with a role in adaptive thermogenesis.","INSTITUTE":"Joslin Diabetes Center - Harvard medical School","DEPARTMENT":"Integrative Physiology and Metabolism","LABORATORY":"Yu-Hua Tseng lab","LAST_NAME":"Leiria","FIRST_NAME":"Luiz","ADDRESS":"One Joslin Place, Boston-MA, USA, 02215","EMAIL":"luiz.leiria@joslin.harvard.edu","PHONE":"1 6173091967"},

"SUBJECT":{"SUBJECT_TYPE":"Mammal","SUBJECT_SPECIES":"Mus musculus","TAXONOMY_ID":"10090"},
"SUBJECT_SAMPLE_FACTORS":[
{
"Subject ID":"-",
"Sample ID":"Control 1",
"Factors":{"Temperature":"22C","Time of exposure":"1 hour"}
},
{
"Subject ID":"-",
"Sample ID":"Control 2",
"Factors":{"Temperature":"22C","Time of exposure":"1 hour"}
},
{
"Subject ID":"-",
"Sample ID":"Control 3",
"Factors":{"Temperature":"22C","Time of exposure":"1 hour"}
},
{
"Subject ID":"-",
"Sample ID":"Control 4",
"Factors":{"Temperature":"22C","Time of exposure":"1 hour"}
},
{
"Subject ID":"-",
"Sample ID":"Control 5",
"Factors":{"Temperature":"22C","Time of exposure":"1 hour"}
},
{
"Subject ID":"-",
"Sample ID":"Control 6",
"Factors":{"Temperature":"22C","Time of exposure":"1 hour"}
},
{
"Subject ID":"-",
"Sample ID":"1-hr cold 1",
"Factors":{"Temperature":"5C","Time of exposure":"1 hour"}
},
{
"Subject ID":"-",
"Sample ID":"1-hr cold 2",
"Factors":{"Temperature":"5C","Time of exposure":"1 hour"}
},
{
"Subject ID":"-",
"Sample ID":"1-hr cold 3",
"Factors":{"Temperature":"5C","Time of exposure":"1 hour"}
},
{
"Subject ID":"-",
"Sample ID":"1-hr cold 4",
"Factors":{"Temperature":"5C","Time of exposure":"1 hour"}
},
{
"Subject ID":"-",
"Sample ID":"1-hr cold 5",
"Factors":{"Temperature":"5C","Time of exposure":"1 hour"}
},
{
"Subject ID":"-",
"Sample ID":"Thermoneutral 1 male",
"Factors":{"Temperature":"30C","Time of exposure":"7 days"}
},
{
"Subject ID":"-",
"Sample ID":"Thermoneutral 2 male",
"Factors":{"Temperature":"30C","Time of exposure":"7 days"}
},
{
"Subject ID":"-",
"Sample ID":"Thermoneutral 3 male",
"Factors":{"Temperature":"30C","Time of exposure":"7 days"}
},
{
"Subject ID":"-",
"Sample ID":"Thermoneutral 4 male",
"Factors":{"Temperature":"30C","Time of exposure":"7 days"}
},
{
"Subject ID":"-",
"Sample ID":"Thermoneutral 5 male",
"Factors":{"Temperature":"30C","Time of exposure":"7 days"}
},
{
"Subject ID":"-",
"Sample ID":"Thermoneutral 6 male",
"Factors":{"Temperature":"30C","Time of exposure":"7 days"}
},
{
"Subject ID":"-",
"Sample ID":"Thermoneutral 1 female",
"Factors":{"Temperature":"30C","Time of exposure":"7 days"}
},
{
"Subject ID":"-",
"Sample ID":"Thermoneutral 2 female",
"Factors":{"Temperature":"30C","Time of exposure":"7 days"}
},
{
"Subject ID":"-",
"Sample ID":"Thermoneutral 3 female",
"Factors":{"Temperature":"30C","Time of exposure":"7 days"}
},
{
"Subject ID":"-",
"Sample ID":"Thermoneutral 4 female",
"Factors":{"Temperature":"30C","Time of exposure":"7 days"}
},
{
"Subject ID":"-",
"Sample ID":"Thermoneutral 5 female",
"Factors":{"Temperature":"30C","Time of exposure":"7 days"}
},
{
"Subject ID":"-",
"Sample ID":"Thermoneutral 6 female",
"Factors":{"Temperature":"30C","Time of exposure":"7 days"}
},
{
"Subject ID":"-",
"Sample ID":"Cold 1 male",
"Factors":{"Temperature":"5C","Time of exposure":"7 days"}
},
{
"Subject ID":"-",
"Sample ID":"Cold 2 male",
"Factors":{"Temperature":"5C","Time of exposure":"7 days"}
},
{
"Subject ID":"-",
"Sample ID":"Cold 3 male",
"Factors":{"Temperature":"5C","Time of exposure":"7 days"}
},
{
"Subject ID":"-",
"Sample ID":"Cold 4 male",
"Factors":{"Temperature":"5C","Time of exposure":"7 days"}
},
{
"Subject ID":"-",
"Sample ID":"Cold 5 male",
"Factors":{"Temperature":"5C","Time of exposure":"7 days"}
},
{
"Subject ID":"-",
"Sample ID":"Cold 1 female",
"Factors":{"Temperature":"5C","Time of exposure":"7 days"}
},
{
"Subject ID":"-",
"Sample ID":"Cold 2 female",
"Factors":{"Temperature":"5C","Time of exposure":"7 days"}
},
{
"Subject ID":"-",
"Sample ID":"Cold 3 female",
"Factors":{"Temperature":"5C","Time of exposure":"7 days"}
},
{
"Subject ID":"-",
"Sample ID":"Cold 4 female",
"Factors":{"Temperature":"5C","Time of exposure":"7 days"}
},
{
"Subject ID":"-",
"Sample ID":"Cold 5 female",
"Factors":{"Temperature":"5C","Time of exposure":"7 days"}
}
],
"COLLECTION":{"COLLECTION_SUMMARY":"Mice were anaesthethized with isoflurane, the blood collected through cardiac puncture, and left under room temperature for 30 minutes. After that, the blood was centrifuged for 3 minutes at 14,000 rpm. Then, serum was transferred for a clean 1.5ml microbe and frost.","SAMPLE_TYPE":"Blood (serum)","STORAGE_CONDITIONS":"-20℃"},

"TREATMENT":{"TREATMENT_SUMMARY":"We divided the C57BL6/J mice in 6 groups: females housed in 30C degree for 1 week and females housed in 5C degree for 1 week; Males housed in 30C degree for 1 week and females housed in 5C degree for 1 week; males housed in 22C for 1 hour and males housed in 5C for 1 hour."},

"SAMPLEPREP":{"SAMPLEPREP_SUMMARY":"Aliquots of 100 µL serum or were taken. A mixture of deuterium-labeled internal standards was added to each aliquot, followed by 3x volume of sample of cold methanol (MeOH). Samples were vortexed for 5 minutes and stored at −20 °C overnight. Cold samples were centrifuged at 14,000g for 10 minutes, and the supernatant was then transferred to a new tube and 3 mL of acidified H2O (pH 3.5) was added to each sample prior to C18 SPE. The methyl formate fractions were collected, dried under nitrogen, and reconstituted in 50 µL MeOH:H2O (1:1, by vol). Samples were transferred to 0.5 mL tubes and centrifuged at 20,000g at 4 °C for 10 minutes. (35ul) of supernatant was transferred to LC–MS/MS vials for analysis using the BERG LC–MS/MS mediator lipidomics platform."},

"CHROMATOGRAPHY":{"CHROMATOGRAPHY_TYPE":"UHPLC","INSTRUMENT_NAME":"Ekspert MicroLC 200 system","COLUMN_NAME":"Synergi™ Fusion-RP capillary C18 column (150 × 0.5 mm, 4 µm; Phenomenex Inc., Torrance, CA, USA) Inc., Torrance, CA, USA)"},

"ANALYSIS":{"ANALYSIS_TYPE":"MS"},

"MS":{"INSTRUMENT_NAME":"ABI Sciex 5600+ TripleTOF","INSTRUMENT_TYPE":"QTOF","MS_TYPE":"ESI","ION_MODE":"NEGATIVE","MS_COMMENTS":"MS spectra were acquired in high-resolution mode (>30,000) using a 100-ms accumulation time per spectrum. Full-scan MS/MS was acquired in high sensitivity mode, with an accumulation time optimized per cycle. Collision energy was set using rolling collision energy with a spread of 15V. The identity of a component was confirmed using PeakView® software (SCIEX), and quantification was performed using MultiQuant™ software (SCIEX)."},

"MS_METABOLITE_DATA":{
"Units":"Peak Area",

"Data":[{"Metabolite":"Tetranor-12-HETE","Control 1":"0.103361624","Control 2":"0.13084113","Control 3":"0.132209497","Control 4":"0.099052739","Control 5":"0.232061591","Control 6":"0.060153185","1-hr cold 1":"0.375497846","1-hr cold 2":"0.275582031","1-hr cold 3":"0.11050684","1-hr cold 4":"0.160087266","1-hr cold 5":"0.08055373","Thermoneutral 1 male":"0.187518773","Thermoneutral 2 male":"0.096276242","Thermoneutral 3 male":"0.073347491","Thermoneutral 4 male":"0.07785385","Thermoneutral 5 male":"0.054273817","Thermoneutral 6 male":"0.04336849","Thermoneutral 1 female":"0.190362029","Thermoneutral 2 female":"0.079343185","Thermoneutral 3 female":"0.101073707","Thermoneutral 4 female":"0.187009603","Thermoneutral 5 female":"0.177612232","Thermoneutral 6 female":"0.025267902","Cold 1 male":"0.049561418","Cold 2 male":"0.177184754","Cold 3 male":"0.216764486","Cold 4 male":"0.356143128","Cold 5 male":"0.268737333","Cold 1 female":"0.186690847","Cold 2 female":"0.088434634","Cold 3 female":"0.142817292","Cold 4 female":"0.162586125","Cold 5 female":"0.117024178"},{"Metabolite":"9-oxoODE","Control 1":"1.364433328","Control 2":"0.424171502","Control 3":"0.472343471","Control 4":"0.420319644","Control 5":"0.599998186","Control 6":"0.504545473","1-hr cold 1":"0.915235927","1-hr cold 2":"0.898296754","1-hr cold 3":"0.714979584","1-hr cold 4":"0.723914602","1-hr cold 5":"0.715808057","Thermoneutral 1 male":"0.919287688","Thermoneutral 2 male":"0.611905857","Thermoneutral 3 male":"0.545277599","Thermoneutral 4 male":"0.345329831","Thermoneutral 5 male":"0.70891417","Thermoneutral 6 male":"0.415792101","Thermoneutral 1 female":"3.391181312","Thermoneutral 2 female":"0.765251814","Thermoneutral 3 female":"0.598185085","Thermoneutral 4 female":"1.027177089","Thermoneutral 5 female":"0.639393702","Thermoneutral 6 female":"0.907677388","Cold 1 male":"0.505463236","Cold 2 male":"1.216442975","Cold 3 male":"1.520452823","Cold 4 male":"0.860975686","Cold 5 male":"0.596079537","Cold 1 female":"0.434146544","Cold 2 female":"0.726386779","Cold 3 female":"0.726362961","Cold 4 female":"0.673676798","Cold 5 female":"0.572454327"},{"Metabolite":"13-oxoODE","Control 1":"3.082239267","Control 2":"0.874135126","Control 3":"0.994515134","Control 4":"1.020325298","Control 5":"1.213929321","Control 6":"1.120508544","1-hr cold 1":"1.719628787","1-hr cold 2":"1.799266551","1-hr cold 3":"1.213287547","1-hr cold 4":"1.608715149","1-hr cold 5":"1.48854004","Thermoneutral 1 male":"1.866794207","Thermoneutral 2 male":"1.222882509","Thermoneutral 3 male":"1.453450696","Thermoneutral 4 male":"0.617882011","Thermoneutral 5 male":"1.091745823","Thermoneutral 6 male":"0.870161057","Thermoneutral 1 female":"9.257728982","Thermoneutral 2 female":"1.474547667","Thermoneutral 3 female":"1.466393575","Thermoneutral 4 female":"2.045701026","Thermoneutral 5 female":"1.307146138","Thermoneutral 6 female":"1.697085235","Cold 1 male":"1.383693567","Cold 2 male":"3.058465779","Cold 3 male":"3.238981042","Cold 4 male":"1.877372506","Cold 5 male":"1.426172576","Cold 1 female":"0.864581863","Cold 2 female":"1.564656761","Cold 3 female":"1.055300901","Cold 4 female":"1.345034203","Cold 5 female":"1.059417265"},{"Metabolite":"9-HOTrE","Control 1":"1.941578481","Control 2":"1.147622017","Control 3":"1.17835718","Control 4":"0.712565897","Control 5":"1.016704156","Control 6":"1.144005826","1-hr cold 1":"1.991546412","1-hr cold 2":"2.35174825","1-hr cold 3":"2.063893871","1-hr cold 4":"2.025657359","1-hr cold 5":"1.597269947","Thermoneutral 1 male":"1.584103452","Thermoneutral 2 male":"1.334069337","Thermoneutral 3 male":"0.965236078","Thermoneutral 4 male":"0.855119657","Thermoneutral 5 male":"1.279406492","Thermoneutral 6 male":"0.945751624","Thermoneutral 1 female":"2.893581347","Thermoneutral 2 female":"2.004129579","Thermoneutral 3 female":"1.242537674","Thermoneutral 4 female":"1.143763891","Thermoneutral 5 female":"1.782648087","Thermoneutral 6 female":"1.702126217","Cold 1 male":"1.366197884","Cold 2 male":"1.712842446","Cold 3 male":"1.708407463","Cold 4 male":"1.712632943","Cold 5 male":"1.1501211","Cold 1 female":"1.22730276","Cold 2 female":"1.468056571","Cold 3 female":"1.625211017","Cold 4 female":"1.470806145","Cold 5 female":"1.249964544"},{"Metabolite":"13-HOTrE/13-HOTrE(r)","Control 1":"0.770542362","Control 2":"0.050461757","Control 3":"0.16867443","Control 4":"0.088493089","Control 5":"0.130842199","Control 6":"0.180213487","1-hr cold 1":"0.56273246","1-hr cold 2":"0.296935755","1-hr cold 3":"0.210689159","1-hr cold 4":"0.286577101","1-hr cold 5":"0.211841743","Thermoneutral 1 male":"0.317567744","Thermoneutral 2 male":"0.182384384","Thermoneutral 3 male":"0.222875903","Thermoneutral 4 male":"0.100490313","Thermoneutral 5 male":"0.191170057","Thermoneutral 6 male":"0.062876139","Thermoneutral 1 female":"1.603088726","Thermoneutral 2 female":"0.201661296","Thermoneutral 3 female":"0.254988433","Thermoneutral 4 female":"0.36166162","Thermoneutral 5 female":"0.202443127","Thermoneutral 6 female":"0.281854241","Cold 1 male":"0.2285455","Cold 2 male":"0.55144749","Cold 3 male":"0.541262439","Cold 4 male":"0.145796948","Cold 5 male":"0.125559998","Cold 1 female":"0.073382014","Cold 2 female":"0.224362279","Cold 3 female":"0.16089717","Cold 4 female":"0.16212871","Cold 5 female":"0.012427784"},{"Metabolite":"9-HODE","Control 1":"2.241549823","Control 2":"1.253951833","Control 3":"1.233370334","Control 4":"1.351300445","Control 5":"1.77089986","Control 6":"1.534060626","1-hr cold 1":"1.918163881","1-hr cold 2":"2.493617743","1-hr cold 3":"2.275503472","1-hr cold 4":"2.336030078","1-hr cold 5":"1.947940414","Thermoneutral 1 male":"3.367767576","Thermoneutral 2 male":"2.943001667","Thermoneutral 3 male":"1.502468055","Thermoneutral 4 male":"1.888733169","Thermoneutral 5 male":"2.410412683","Thermoneutral 6 male":"2.734692261","Thermoneutral 1 female":"6.977244406","Thermoneutral 2 female":"2.764134125","Thermoneutral 3 female":"2.012396661","Thermoneutral 4 female":"2.844922718","Thermoneutral 5 female":"3.595739124","Thermoneutral 6 female":"3.285774489","Cold 1 male":"1.487479022","Cold 2 male":"2.295774518","Cold 3 male":"4.249168668","Cold 4 male":"2.369277385","Cold 5 male":"2.727535925","Cold 1 female":"1.781294509","Cold 2 female":"3.105111558","Cold 3 female":"2.674811649","Cold 4 female":"3.150464807","Cold 5 female":"2.217220718"},{"Metabolite":"13-HODE","Control 1":"3.32121357","Control 2":"1.728473838","Control 3":"1.687219935","Control 4":"1.97338975","Control 5":"2.75880711","Control 6":"2.400989412","1-hr cold 1":"3.203430319","1-hr cold 2":"3.722984146","1-hr cold 3":"3.535762553","1-hr cold 4":"3.982092132","1-hr cold 5":"3.045686643","Thermoneutral 1 male":"6.019952175","Thermoneutral 2 male":"4.940778464","Thermoneutral 3 male":"4.891799706","Thermoneutral 4 male":"3.028468707","Thermoneutral 5 male":"4.041210465","Thermoneutral 6 male":"4.526236401","Thermoneutral 1 female":"12.13256058","Thermoneutral 2 female":"5.335367056","Thermoneutral 3 female":"3.452698037","Thermoneutral 4 female":"4.852815817","Thermoneutral 5 female":"7.804959273","Thermoneutral 6 female":"6.141250709","Cold 1 male":"3.846667572","Cold 2 male":"9.265223815","Cold 3 male":"8.807482026","Cold 4 male":"2.497431931","Cold 5 male":"6.093110311","Cold 1 female":"3.201671756","Cold 2 female":"5.784744769","Cold 3 female":"4.803420645","Cold 4 female":"5.599625048","Cold 5 female":"3.760778295"},{"Metabolite":"9(10)-EpOME","Control 1":"27.23281836","Control 2":"17.70589097","Control 3":"16.67189578","Control 4":"9.047784099","Control 5":"15.29250715","Control 6":"19.40981352","1-hr cold 1":"29.76651141","1-hr cold 2":"47.36815542","1-hr cold 3":"32.63038106","1-hr cold 4":"23.36744236","1-hr cold 5":"25.04019836","Thermoneutral 1 male":"16.10640716","Thermoneutral 2 male":"19.43571869","Thermoneutral 3 male":"14.64236844","Thermoneutral 4 male":"8.650525617","Thermoneutral 5 male":"15.05647194","Thermoneutral 6 male":"13.08015053","Thermoneutral 1 female":"43.46170656","Thermoneutral 2 female":"26.42531808","Thermoneutral 3 female":"20.86614109","Thermoneutral 4 female":"18.85896789","Thermoneutral 5 female":"28.45969817","Thermoneutral 6 female":"22.25370786","Cold 1 male":"28.86397131","Cold 2 male":"31.18633605","Cold 3 male":"40.97656081","Cold 4 male":"30.02675288","Cold 5 male":"19.52815714","Cold 1 female":"16.39287713","Cold 2 female":"28.28033361","Cold 3 female":"29.33294373","Cold 4 female":"27.8931487","Cold 5 female":"22.3356238"},{"Metabolite":"12(13)-EpOME","Control 1":"3.243874862","Control 2":"1.674273271","Control 3":"1.630307031","Control 4":"1.916455523","Control 5":"2.694326492","Control 6":"2.365860144","1-hr cold 1":"3.185810973","1-hr cold 2":"3.659734405","1-hr cold 3":"3.432306412","1-hr cold 4":"3.918378247","1-hr cold 5":"3.02094785","Thermoneutral 1 male":"5.862490424","Thermoneutral 2 male":"4.875434014","Thermoneutral 3 male":"4.763467061","Thermoneutral 4 male":"2.939782683","Thermoneutral 5 male":"3.925732004","Thermoneutral 6 male":"4.423978367","Thermoneutral 1 female":"11.71220763","Thermoneutral 2 female":"5.18161894","Thermoneutral 3 female":"3.35182021","Thermoneutral 4 female":"4.766154918","Thermoneutral 5 female":"7.623075731","Thermoneutral 6 female":"5.961290252","Cold 1 male":"3.751698869","Cold 2 male":"9.049930958","Cold 3 male":"8.65046648","Cold 4 male":"2.446487284","Cold 5 male":"5.893487424","Cold 1 female":"3.133927067","Cold 2 female":"5.614783665","Cold 3 female":"4.665974011","Cold 4 female":"5.496580905","Cold 5 female":"3.683600111"},{"Metabolite":"9,10-diHOME","Control 1":"3.511910864","Control 2":"6.858641644","Control 3":"5.988926882","Control 4":"4.347983593","Control 5":"3.901431275","Control 6":"5.295549274","1-hr cold 1":"6.653094586","1-hr cold 2":"9.282562671","1-hr cold 3":"6.200418977","1-hr cold 4":"11.86480814","1-hr cold 5":"10.65611048","Thermoneutral 1 male":"3.651305945","Thermoneutral 2 male":"8.513936521","Thermoneutral 3 male":"1.53216015","Thermoneutral 4 male":"2.901693875","Thermoneutral 5 male":"2.533264574","Thermoneutral 6 male":"3.157623164","Thermoneutral 1 female":"8.485239832","Thermoneutral 2 female":"4.467241767","Thermoneutral 3 female":"3.338469219","Thermoneutral 4 female":"5.453840498","Thermoneutral 5 female":"5.86285556","Thermoneutral 6 female":"3.731328035","Cold 1 male":"4.888263889","Cold 2 male":"8.42948938","Cold 3 male":"6.137122757","Cold 4 male":"8.633084428","Cold 5 male":"8.315516125","Cold 1 female":"2.775459571","Cold 2 female":"9.145745017","Cold 3 female":"8.560451941","Cold 4 female":"10.77083311","Cold 5 female":"5.845446562"},{"Metabolite":"12,13-diHOME","Control 1":"8.165083195","Control 2":"16.60376917","Control 3":"13.45176973","Control 4":"10.87471869","Control 5":"10.20242397","Control 6":"12.84068777","1-hr cold 1":"12.75507711","1-hr cold 2":"19.05456722","1-hr cold 3":"12.64872239","1-hr cold 4":"26.88487917","1-hr cold 5":"24.47405973","Thermoneutral 1 male":"9.676653919","Thermoneutral 2 male":"19.23485816","Thermoneutral 3 male":"3.203332622","Thermoneutral 4 male":"6.613200584","Thermoneutral 5 male":"7.388816965","Thermoneutral 6 male":"12.03713108","Thermoneutral 1 female":"19.73059757","Thermoneutral 2 female":"12.58720911","Thermoneutral 3 female":"6.741113416","Thermoneutral 4 female":"14.82877427","Thermoneutral 5 female":"17.06289467","Thermoneutral 6 female":"9.78478305","Cold 1 male":"10.89291657","Cold 2 male":"17.52186879","Cold 3 male":"14.10012525","Cold 4 male":"22.14484385","Cold 5 male":"21.26101206","Cold 1 female":"6.233036901","Cold 2 female":"21.58941718","Cold 3 female":"19.65025736","Cold 4 female":"24.7544285","Cold 5 female":"13.50035583"},{"Metabolite":"15-deoxy-delta12,14-PGJ2","Control 1":"0.039757294","Control 2":"0.038908614","Control 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ID":"16759351"},{"Metabolite":"8-HETrE","PUBCHEM ID":"71306337 "},{"Metabolite":"15-HETrE","PUBCHEM ID":"44322431"},{"Metabolite":"2,3-dinor-11beta-PGF2a","PUBCHEM ID":""},{"Metabolite":"tetranor-PGFM","PUBCHEM ID":"3246853"},{"Metabolite":"12-oxoLTB4","PUBCHEM ID":""},{"Metabolite":"PGA2/PGJ2","PUBCHEM ID":"5280880"},{"Metabolite":"PGB2","PUBCHEM ID":"5280881"},{"Metabolite":"15-deoxy-delta12,14-PGD2","PUBCHEM ID":"5283052"},{"Metabolite":"13,14-dihydro-15-keto PGA2","PUBCHEM ID":"5283042"},{"Metabolite":"Bicyclo PGE2","PUBCHEM ID":"5283043"},{"Metabolite":"delta12-PGJ2","PUBCHEM ID":"5280885"},{"Metabolite":"LTB4","PUBCHEM ID":"5280492 "},{"Metabolite":"5,6-diHETE","PUBCHEM ID":"14429105"},{"Metabolite":"5,15-diHETE","PUBCHEM ID":"5283158"},{"Metabolite":"Hepoxilin A3","PUBCHEM ID":"5283211"},{"Metabolite":"14,15-diHETE","PUBCHEM ID":"16061119"},{"Metabolite":"17,18-diHETE","PUBCHEM ID":"16061120"},{"Metabolite":"PGA1","PUBCHEM ID":"5281912"},{"Metabolite":"5,6-diHETrE","PUBCHEM ID":"5283142"},{"Metabolite":"8,9-diHETrE","PUBCHEM ID":"5283144"},{"Metabolite":"11,12-diHETrE","PUBCHEM ID":"5283146"},{"Metabolite":"14,15-diHETrE","PUBCHEM ID":"5283147"},{"Metabolite":"2,3-dinor TxB2","PUBCHEM ID":"6438342"},{"Metabolite":"17-HDHA","PUBCHEM ID":"132282537"},{"Metabolite":"14-HDHA","PUBCHEM ID":"52921998"},{"Metabolite":"7-HDHA","PUBCHEM ID":"132472337"},{"Metabolite":"4-HDHA","PUBCHEM ID":""},{"Metabolite":"8-HDHA","PUBCHEM ID":""},{"Metabolite":"10-HDHA","PUBCHEM ID":""},{"Metabolite":"11-HDHA","PUBCHEM ID":""},{"Metabolite":"13-HDHA","PUBCHEM ID":"102571766"},{"Metabolite":"16-HDHA","PUBCHEM ID":""},{"Metabolite":"20-HDHA","PUBCHEM ID":""},{"Metabolite":"19(20)-EpDPE","PUBCHEM ID":"11631565"},{"Metabolite":"16(17)-EpDPE","PUBCHEM ID":"14392758"},{"Metabolite":"PGD3/PGE3","PUBCHEM ID":"5282260"},{"Metabolite":"15-keto-PGE2","PUBCHEM ID":"5280719"},{"Metabolite":"PGK2","PUBCHEM ID":"5283037"},{"Metabolite":"13,14-dihydro-15-keto PGE2","PUBCHEM ID":"5280711"},{"Metabolite":"13,14-dihydro-15-keto PGD2","PUBCHEM ID":"5283036"},{"Metabolite":"15-keto-PGF2a","PUBCHEM ID":"5280887"},{"Metabolite":"PGE2/PGD2","PUBCHEM ID":"5280360"},{"Metabolite":"PGD2","PUBCHEM ID":"448457"},{"Metabolite":"LXA4","PUBCHEM ID":"5280914"},{"Metabolite":"LXB4","PUBCHEM ID":"5280915"},{"Metabolite":"PGF2a","PUBCHEM ID":"5280363"},{"Metabolite":"8-iso PGF2a","PUBCHEM ID":"5282263"},{"Metabolite":"5-iPF2a-VI","PUBCHEM ID":""},{"Metabolite":"PGE1/PGD1","PUBCHEM ID":"5280723"},{"Metabolite":"11-beta-PGF2a/PGF2b","PUBCHEM ID":"5280506"},{"Metabolite":"13,14-dihydro-15-keto PGF2a","PUBCHEM ID":"5283039"},{"Metabolite":"Maresin1","PUBCHEM ID":"60201795"},{"Metabolite":"PD1","PUBCHEM ID":"71508666"},{"Metabolite":"19,20-diHDPA","PUBCHEM ID":"16061148"},{"Metabolite":"20-carboxy LTB4","PUBCHEM ID":"5280877"},{"Metabolite":"TxB3","PUBCHEM ID":"5283140"},{"Metabolite":"11-dehydro TxB2","PUBCHEM ID":"1409"},{"Metabolite":"19/20-OH PGE2","PUBCHEM ID":""},{"Metabolite":"6-keto PGE1","PUBCHEM ID":"5280889"},{"Metabolite":"TxB2","PUBCHEM ID":"5283137"},{"Metabolite":"6-keto-PGF1a","PUBCHEM ID":"5280888"},{"Metabolite":"19/20-OH PGF2a","PUBCHEM ID":""},{"Metabolite":"6,15-diketo-13,14-dihydro PGF1a","PUBCHEM ID":"5283033"},{"Metabolite":"RvD1","PUBCHEM ID":"44251266"},{"Metabolite":"RvD2","PUBCHEM ID":"11383310"},{"Metabolite":"LTE4","PUBCHEM ID":"5280879"},{"Metabolite":"LTD4","PUBCHEM ID":"5280878"},{"Metabolite":"LTC4","PUBCHEM ID":"5280493"},{"Metabolite":"d4-9-HODE","PUBCHEM ID":""},{"Metabolite":"d8-5S-HETE","PUBCHEM ID":"5283153"},{"Metabolite":"d4-LTB4","PUBCHEM ID":"16061113"},{"Metabolite":"d4-PGE2","PUBCHEM ID":"5283031"},{"Metabolite":"PGF1a","PUBCHEM ID":"6473774"},{"Metabolite":"13,14-dihydro PGE1","PUBCHEM ID":"161273"}]
}

}