{
"METABOLOMICS WORKBENCH":{"STUDY_ID":"ST001349","ANALYSIS_ID":"AN002243","VERSION":"1","CREATED_ON":"April 7, 2020, 12:44 pm"},

"PROJECT":{"PROJECT_TITLE":"Serum Metabolome of Simmental Dairy Cows Switched to High-Grain Diet during Early Lactation","PROJECT_SUMMARY":"In dairy cows, early lactation is associated with an energy deficit that is counteracted by increasing the amounts of grains in the diet. Yet, such diet often increases the odds for cows to develop digestive and systemic metabolic derailments, which can likely be detected as undesirable shifts in the serum metabolome. The present study aimed to identify the metabolic signatures of the serum metabolome of early lactation dairy cows fed high-grain diet.","INSTITUTE":"Institute of Animal Nutrition and Functional Plant Compounds","DEPARTMENT":"Department for Farm Animals and Veterinary Public Health","LABORATORY":"Christian Doppler Laboratory for Innovative Gut Health Concepts of Livestock","LAST_NAME":"Pacífico","FIRST_NAME":"Cátia","ADDRESS":"Veterinaerplatz 1","EMAIL":"catia.pacifico@vetmeduni.ac.at","PHONE":"+436608389796"},

"STUDY":{"STUDY_TITLE":"Multiparous and Primiparous Simmental Dairy Cows","STUDY_SUMMARY":"Targeted ESI-LC-MS/MS-based metabolomics was used to characterize metabolic alterations in the serum of cows, according to parities and feeding phase.","INSTITUTE":"Institute of Animal Nutrition and Functional Plant Compounds","DEPARTMENT":"Department for Farm Animals and Veterinary Public Health","LABORATORY":"Christian Doppler Laboratory for Innovative Gut Health Concepts of Livestock","LAST_NAME":"Pacífico","FIRST_NAME":"Cátia","ADDRESS":"Veterinaerplatz 1","EMAIL":"catia.pacifico@vetmeduni.ac.at","PHONE":"06608389796","TOTAL_SUBJECTS":"24","NUM_MALES":"-","NUM_FEMALES":"24"},

"SUBJECT":{"SUBJECT_TYPE":"Mammal","SUBJECT_SPECIES":"Bos taurus","TAXONOMY_ID":"9913","GENDER":"Female"},
"SUBJECT_SAMPLE_FACTORS":[
{
"Subject ID":"-",
"Sample ID":"cow 11_Day 7",
"Factors":{"Day":"7","Group":"control","Parity":"primiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.05.18"}
},
{
"Subject ID":"-",
"Sample ID":"cow 14_Day 7",
"Factors":{"Day":"7","Group":"control","Parity":"primiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.06.28"}
},
{
"Subject ID":"-",
"Sample ID":"cow 2_Day 7",
"Factors":{"Day":"7","Group":"control","Parity":"primiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.05.09"}
},
{
"Subject ID":"-",
"Sample ID":"cow 21_Day 7",
"Factors":{"Day":"7","Group":"control","Parity":"primiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.08.20"}
},
{
"Subject ID":"-",
"Sample ID":"cow 1_Day 14",
"Factors":{"Day":"14","Group":"control","Parity":"multiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.05.08"}
},
{
"Subject ID":"-",
"Sample ID":"cow 11_Day 14",
"Factors":{"Day":"14","Group":"control","Parity":"primiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.05.18"}
},
{
"Subject ID":"-",
"Sample ID":"cow 12_Day 14",
"Factors":{"Day":"14","Group":"control","Parity":"multiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.05.16"}
},
{
"Subject ID":"-",
"Sample ID":"cow 13_Day 14",
"Factors":{"Day":"14","Group":"control","Parity":"multiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.06.20"}
},
{
"Subject ID":"-",
"Sample ID":"cow 14_Day 14",
"Factors":{"Day":"14","Group":"control","Parity":"primiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.06.28"}
},
{
"Subject ID":"-",
"Sample ID":"cow 15_Day 14",
"Factors":{"Day":"14","Group":"control","Parity":"multiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.04.28"}
},
{
"Subject ID":"-",
"Sample ID":"cow 2_Day 14",
"Factors":{"Day":"14","Group":"control","Parity":"primiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.05.09"}
},
{
"Subject ID":"-",
"Sample ID":"cow 21_Day 14",
"Factors":{"Day":"14","Group":"control","Parity":"primiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.08.20"}
},
{
"Subject ID":"-",
"Sample ID":"cow 22_Day 14",
"Factors":{"Day":"14","Group":"control","Parity":"multiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.06.22"}
},
{
"Subject ID":"-",
"Sample ID":"cow 3_Day 14",
"Factors":{"Day":"14","Group":"control","Parity":"multiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.04.27"}
},
{
"Subject ID":"-",
"Sample ID":"cow 4_Day 14",
"Factors":{"Day":"14","Group":"control","Parity":"multiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.02.28"}
},
{
"Subject ID":"-",
"Sample ID":"cow 5_Day 14",
"Factors":{"Day":"14","Group":"control","Parity":"multiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.04.20"}
},
{
"Subject ID":"-",
"Sample ID":"cow 1_Day 21",
"Factors":{"Day":"21","Group":"control","Parity":"multiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.05.08"}
},
{
"Subject ID":"-",
"Sample ID":"cow 11_Day 21",
"Factors":{"Day":"21","Group":"control","Parity":"primiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.05.18"}
},
{
"Subject ID":"-",
"Sample ID":"cow 12_Day 21",
"Factors":{"Day":"21","Group":"control","Parity":"multiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.05.16"}
},
{
"Subject ID":"-",
"Sample ID":"cow 13_Day 21",
"Factors":{"Day":"21","Group":"control","Parity":"multiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.06.20"}
},
{
"Subject ID":"-",
"Sample ID":"cow 14_Day 21",
"Factors":{"Day":"21","Group":"control","Parity":"primiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.06.28"}
},
{
"Subject ID":"-",
"Sample ID":"cow 15_Day 21",
"Factors":{"Day":"21","Group":"control","Parity":"multiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.04.28"}
},
{
"Subject ID":"-",
"Sample ID":"cow 2_Day 21",
"Factors":{"Day":"21","Group":"control","Parity":"primiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.05.09"}
},
{
"Subject ID":"-",
"Sample ID":"cow 21_Day 21",
"Factors":{"Day":"21","Group":"control","Parity":"primiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.08.20"}
},
{
"Subject ID":"-",
"Sample ID":"cow 22_Day 21",
"Factors":{"Day":"21","Group":"control","Parity":"multiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.06.22"}
},
{
"Subject ID":"-",
"Sample ID":"cow 3_Day 21",
"Factors":{"Day":"21","Group":"control","Parity":"multiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.04.27"}
},
{
"Subject ID":"-",
"Sample ID":"cow 4_Day 21",
"Factors":{"Day":"21","Group":"control","Parity":"multiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.02.28"}
},
{
"Subject ID":"-",
"Sample ID":"cow 5_Day 21",
"Factors":{"Day":"21","Group":"control","Parity":"multiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.04.20"}
},
{
"Subject ID":"-",
"Sample ID":"cow 1_Day 42",
"Factors":{"Day":"42","Group":"control","Parity":"multiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.05.08"}
},
{
"Subject ID":"-",
"Sample ID":"cow 11_Day 42",
"Factors":{"Day":"42","Group":"control","Parity":"primiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.05.18"}
},
{
"Subject ID":"-",
"Sample ID":"cow 12_Day 42",
"Factors":{"Day":"42","Group":"control","Parity":"multiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.05.16"}
},
{
"Subject ID":"-",
"Sample ID":"cow 13_Day 42",
"Factors":{"Day":"42","Group":"control","Parity":"multiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.06.20"}
},
{
"Subject ID":"-",
"Sample ID":"cow 14_Day 42",
"Factors":{"Day":"42","Group":"control","Parity":"primiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.06.28"}
},
{
"Subject ID":"-",
"Sample ID":"cow 15_Day 42",
"Factors":{"Day":"42","Group":"control","Parity":"multiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.04.28"}
},
{
"Subject ID":"-",
"Sample ID":"cow 2_Day 42",
"Factors":{"Day":"42","Group":"control","Parity":"primiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.05.09"}
},
{
"Subject ID":"-",
"Sample ID":"cow 21_Day 42",
"Factors":{"Day":"42","Group":"control","Parity":"primiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.08.20"}
},
{
"Subject ID":"-",
"Sample ID":"cow 22_Day 42",
"Factors":{"Day":"42","Group":"control","Parity":"multiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.06.22"}
},
{
"Subject ID":"-",
"Sample ID":"cow 3_Day 42",
"Factors":{"Day":"42","Group":"control","Parity":"multiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.04.27"}
},
{
"Subject ID":"-",
"Sample ID":"cow 4_Day 42",
"Factors":{"Day":"42","Group":"control","Parity":"multiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.02.28"}
},
{
"Subject ID":"-",
"Sample ID":"cow 5_Day 42",
"Factors":{"Day":"42","Group":"control","Parity":"multiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.04.20"}
},
{
"Subject ID":"-",
"Sample ID":"cow 16_Day 7",
"Factors":{"Day":"7","Group":"treatment","Parity":"primiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2019.05.27"}
},
{
"Subject ID":"-",
"Sample ID":"cow 17_Day 7",
"Factors":{"Day":"7","Group":"treatment","Parity":"primiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.07.03"}
},
{
"Subject ID":"-",
"Sample ID":"cow 23_Day 7",
"Factors":{"Day":"7","Group":"treatment","Parity":"primiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.08.04"}
},
{
"Subject ID":"-",
"Sample ID":"cow 8_Day 7",
"Factors":{"Day":"7","Group":"treatment","Parity":"primiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.03.02"}
},
{
"Subject ID":"-",
"Sample ID":"cow 10_Day 14",
"Factors":{"Day":"14","Group":"treatment","Parity":"multiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.04.11"}
},
{
"Subject ID":"-",
"Sample ID":"cow 16_Day 14",
"Factors":{"Day":"14","Group":"treatment","Parity":"primiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.05.27"}
},
{
"Subject ID":"-",
"Sample ID":"cow 17_Day 14",
"Factors":{"Day":"14","Group":"treatment","Parity":"primiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.07.03"}
},
{
"Subject ID":"-",
"Sample ID":"cow 18_Day 14",
"Factors":{"Day":"14","Group":"treatment","Parity":"multiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.06.13"}
},
{
"Subject ID":"-",
"Sample ID":"cow 19_Day 14",
"Factors":{"Day":"14","Group":"treatment","Parity":"multiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.06.07"}
},
{
"Subject ID":"-",
"Sample ID":"cow 20_Day 14",
"Factors":{"Day":"14","Group":"treatment","Parity":"multiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.05.28"}
},
{
"Subject ID":"-",
"Sample ID":"cow 23_Day 14",
"Factors":{"Day":"14","Group":"treatment","Parity":"primiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.08.04"}
},
{
"Subject ID":"-",
"Sample ID":"cow 24_Day 14",
"Factors":{"Day":"14","Group":"treatment","Parity":"multiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.07.16"}
},
{
"Subject ID":"-",
"Sample ID":"cow 6_Day 14",
"Factors":{"Day":"14","Group":"treatment","Parity":"multiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.04.23"}
},
{
"Subject ID":"-",
"Sample ID":"cow 7_Day 14",
"Factors":{"Day":"14","Group":"treatment","Parity":"multiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.03.13"}
},
{
"Subject ID":"-",
"Sample ID":"cow 8_Day 14",
"Factors":{"Day":"14","Group":"treatment","Parity":"primiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.03.02"}
},
{
"Subject ID":"-",
"Sample ID":"cow 9_Day 14",
"Factors":{"Day":"14","Group":"treatment","Parity":"multiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.05.11"}
},
{
"Subject ID":"-",
"Sample ID":"cow 10_Day 21",
"Factors":{"Day":"21","Group":"treatment","Parity":"multiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.04.11"}
},
{
"Subject ID":"-",
"Sample ID":"cow 16_Day 21",
"Factors":{"Day":"21","Group":"treatment","Parity":"primiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.05.27"}
},
{
"Subject ID":"-",
"Sample ID":"cow 17_Day 21",
"Factors":{"Day":"21","Group":"treatment","Parity":"primiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.07.03"}
},
{
"Subject ID":"-",
"Sample ID":"cow 18_Day 21",
"Factors":{"Day":"21","Group":"treatment","Parity":"multiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.06.13"}
},
{
"Subject ID":"-",
"Sample ID":"cow 19_Day 21",
"Factors":{"Day":"21","Group":"treatment","Parity":"multiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.06.07"}
},
{
"Subject ID":"-",
"Sample ID":"cow 20_Day 21",
"Factors":{"Day":"21","Group":"treatment","Parity":"multiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.05.28"}
},
{
"Subject ID":"-",
"Sample ID":"cow 23_Day 21",
"Factors":{"Day":"21","Group":"treatment","Parity":"primiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.08.04"}
},
{
"Subject ID":"-",
"Sample ID":"cow 24_Day 21",
"Factors":{"Day":"21","Group":"treatment","Parity":"multiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.07.16"}
},
{
"Subject ID":"-",
"Sample ID":"cow 6_Day 21",
"Factors":{"Day":"21","Group":"treatment","Parity":"multiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.04.23"}
},
{
"Subject ID":"-",
"Sample ID":"cow 7_Day 21",
"Factors":{"Day":"21","Group":"treatment","Parity":"multiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.03.13"}
},
{
"Subject ID":"-",
"Sample ID":"cow 8_Day 21",
"Factors":{"Day":"21","Group":"treatment","Parity":"primiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.03.02"}
},
{
"Subject ID":"-",
"Sample ID":"cow 9_Day 21",
"Factors":{"Day":"21","Group":"treatment","Parity":"multiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.05.11"}
},
{
"Subject ID":"-",
"Sample ID":"cow 10_Day 42",
"Factors":{"Day":"42","Group":"treatment","Parity":"multiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.04.11"}
},
{
"Subject ID":"-",
"Sample ID":"cow 16_Day 42",
"Factors":{"Day":"42","Group":"treatment","Parity":"primiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.05.27"}
},
{
"Subject ID":"-",
"Sample ID":"cow 17_Day 42",
"Factors":{"Day":"42","Group":"treatment","Parity":"primiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.07.03"}
},
{
"Subject ID":"-",
"Sample ID":"cow 18_Day 42",
"Factors":{"Day":"42","Group":"treatment","Parity":"multiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.06.13"}
},
{
"Subject ID":"-",
"Sample ID":"cow 19_Day 42",
"Factors":{"Day":"42","Group":"treatment","Parity":"multiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.06.07"}
},
{
"Subject ID":"-",
"Sample ID":"cow 20_Day 42",
"Factors":{"Day":"42","Group":"treatment","Parity":"multiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.05.28"}
},
{
"Subject ID":"-",
"Sample ID":"cow 23_Day 42",
"Factors":{"Day":"42","Group":"treatment","Parity":"primiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.08.04"}
},
{
"Subject ID":"-",
"Sample ID":"cow 24_Day 42",
"Factors":{"Day":"42","Group":"treatment","Parity":"multiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.07.16"}
},
{
"Subject ID":"-",
"Sample ID":"cow 6_Day 42",
"Factors":{"Day":"42","Group":"treatment","Parity":"multiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.04.23"}
},
{
"Subject ID":"-",
"Sample ID":"cow 7_Day 42",
"Factors":{"Day":"42","Group":"treatment","Parity":"multiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.03.13"}
},
{
"Subject ID":"-",
"Sample ID":"cow 8_Day 42",
"Factors":{"Day":"42","Group":"treatment","Parity":"primiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.03.02"}
},
{
"Subject ID":"-",
"Sample ID":"cow 9_Day 42",
"Factors":{"Day":"42","Group":"treatment","Parity":"multiparous"},
"Additional sample data":{"Species":"cow","Calving date":"2018.05.11"}
}
],
"COLLECTION":{"COLLECTION_SUMMARY":"Blood samples were collected before the morning feeding from the jugular vein of all animals using vacutainer tubes. Samples were allowed to clot at 25°C for 2 h and all tubes were then centrifuged at 2000 × g at 4°C for 15 min to separate serum. Serum was pipetted into 2 mL tubes and stored at -80°C for further analysis.","SAMPLE_TYPE":"Blood (serum)"},

"TREATMENT":{"TREATMENT_SUMMARY":"The feed contained either no additive as a control (CON) or a mineral-based endotoxin binder (EB)."},

"SAMPLEPREP":{"SAMPLEPREP_SUMMARY":"Determination of the serum metabolome was carried out using a targeted metabolomics approach based on the Biocrates MxP® Quant 500 kit. Ten μL aliquots of the serum samples were processed according to the manufacturer’s instructions."},

"CHROMATOGRAPHY":{"CHROMATOGRAPHY_SUMMARY":"RP-LC-MS/MS","CHROMATOGRAPHY_TYPE":"Reversed phase","INSTRUMENT_NAME":"Agilent 1290","COLUMN_NAME":"-","COLUMN_TEMPERATURE":"50 °C","SOLVENT_A":"1 L of water + 2 mL of formic acid","SOLVENT_B":"1 L of acetonitrile + 2 ml of formic acid"},

"ANALYSIS":{"ANALYSIS_TYPE":"MS","DETECTOR_TYPE":"pulse counting detector","SOFTWARE_VERSION":"Analyst 1.6.3.","ACQUISITION_DATE":"12.6.2019-14.6.2019"},

"MS":{"INSTRUMENT_NAME":"Sciex 6500+ QTrap","INSTRUMENT_TYPE":"Triple quadrupole","MS_TYPE":"ESI","ION_MODE":"POSITIVE","MS_COMMENTS":"-"},

"MS_METABOLITE_DATA":{
"Units":"µM",

"Data":[{"Metabolite":"Ala","cow 11_Day 7":"260","cow 14_Day 7":"307","cow 2_Day 7":"253","cow 21_Day 7":"160","cow 1_Day 14":"153","cow 11_Day 14":"248","cow 12_Day 14":"193","cow 13_Day 14":"305","cow 14_Day 14":"333","cow 15_Day 14":"267","cow 2_Day 14":"252","cow 21_Day 14":"224","cow 22_Day 14":"180","cow 3_Day 14":"194","cow 4_Day 14":"212","cow 5_Day 14":"264","cow 1_Day 21":"236","cow 11_Day 21":"213","cow 12_Day 21":"150","cow 13_Day 21":"259","cow 14_Day 21":"279","cow 15_Day 21":"256","cow 2_Day 21":"182","cow 21_Day 21":"201","cow 22_Day 21":"224","cow 3_Day 21":"175","cow 4_Day 21":"214","cow 5_Day 21":"241","cow 1_Day 42":"282","cow 11_Day 42":"238","cow 12_Day 42":"143","cow 13_Day 42":"248","cow 14_Day 42":"300","cow 15_Day 42":"225","cow 2_Day 42":"292","cow 21_Day 42":"204","cow 22_Day 42":"229","cow 3_Day 42":"262","cow 4_Day 42":"223","cow 5_Day 42":"162","cow 16_Day 7":"363","cow 17_Day 7":"203","cow 23_Day 7":"190","cow 8_Day 7":"257","cow 10_Day 14":"210","cow 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1_Day 42":"12.1","cow 11_Day 42":"14.7","cow 12_Day 42":"48.2","cow 13_Day 42":"5.06","cow 14_Day 42":"11.8","cow 15_Day 42":"18.1","cow 2_Day 42":"26.9","cow 21_Day 42":"29.3","cow 22_Day 42":"7.25","cow 3_Day 42":"43.2","cow 4_Day 42":"19.9","cow 5_Day 42":"23.6","cow 16_Day 7":"14.7","cow 17_Day 7":"6.97","cow 23_Day 7":"8.21","cow 8_Day 7":"14.5","cow 10_Day 14":"16.8","cow 16_Day 14":"6.68","cow 17_Day 14":"6.59","cow 18_Day 14":"44.2","cow 19_Day 14":"13.9","cow 20_Day 14":"16.2","cow 23_Day 14":"25","cow 24_Day 14":"11.9","cow 6_Day 14":"15.2","cow 7_Day 14":"112","cow 8_Day 14":"27.7","cow 9_Day 14":"11","cow 10_Day 21":"19.7","cow 16_Day 21":"20.4","cow 17_Day 21":"13.9","cow 18_Day 21":"30.9","cow 19_Day 21":"15.5","cow 20_Day 21":"15.1","cow 23_Day 21":"15.8","cow 24_Day 21":"42.1","cow 6_Day 21":"84.5","cow 7_Day 21":"50","cow 8_Day 21":"26.8","cow 9_Day 21":"27.2","cow 10_Day 42":"16.8","cow 16_Day 42":"10.9","cow 17_Day 42":"18.9","cow 18_Day 42":"22","cow 19_Day 42":"11.9","cow 20_Day 42":"11.5","cow 23_Day 42":"40.9","cow 24_Day 42":"22.1","cow 6_Day 42":"32.2","cow 7_Day 42":"31.4","cow 8_Day 42":"18","cow 9_Day 42":"17.6"}],

"Metabolites":[{"metabolite_name":"Ala"},{"metabolite_name":"Arg"},{"metabolite_name":"Asn"},{"metabolite_name":"Asp"},{"metabolite_name":"Cys"},{"metabolite_name":"Gln"},{"metabolite_name":"Glu"},{"metabolite_name":"Gly"},{"metabolite_name":"His"},{"metabolite_name":"Ile"},{"metabolite_name":"Leu"},{"metabolite_name":"Lys"},{"metabolite_name":"Met"},{"metabolite_name":"Phe"},{"metabolite_name":"Pro"},{"metabolite_name":"Ser"},{"metabolite_name":"Thr"},{"metabolite_name":"Trp"},{"metabolite_name":"Tyr"},{"metabolite_name":"Val"},{"metabolite_name":"beta-Ala"},{"metabolite_name":"GABA"},{"metabolite_name":"Histamine"},{"metabolite_name":"Putrescine"},{"metabolite_name":"Serotonin"},{"metabolite_name":"Spermidine"},{"metabolite_name":"Spermine"},{"metabolite_name":"3-IAA"},{"metabolite_name":"3-IPA"},{"metabolite_name":"1-Met-His"},{"metabolite_name":"3-Met-His"},{"metabolite_name":"5-AVA"},{"metabolite_name":"AABA"},{"metabolite_name":"ADMA"},{"metabolite_name":"alpha-AAA"},{"metabolite_name":"Anserine"},{"metabolite_name":"BABA"},{"metabolite_name":"Betaine"},{"metabolite_name":"c4-OH-Pro"},{"metabolite_name":"Carnosine"},{"metabolite_name":"Cit"},{"metabolite_name":"Creatinine"},{"metabolite_name":"Cystine"},{"metabolite_name":"DOPA"},{"metabolite_name":"HArg"},{"metabolite_name":"HCys"},{"metabolite_name":"Kynurenine"},{"metabolite_name":"Met-SO"},{"metabolite_name":"Orn"},{"metabolite_name":"PAG"},{"metabolite_name":"ProBetaine"},{"metabolite_name":"Sarcosine"},{"metabolite_name":"SDMA"},{"metabolite_name":"t4-OH-Pro"},{"metabolite_name":"Taurine"},{"metabolite_name":"TrpBetaine"},{"metabolite_name":"Cortisol"},{"metabolite_name":"Cortisone"},{"metabolite_name":"Choline"},{"metabolite_name":"TMAO"}]
}

}