{
"METABOLOMICS WORKBENCH":{"STUDY_ID":"ST001620","ANALYSIS_ID":"AN002655","VERSION":"1","CREATED_ON":"December 11, 2020, 9:53 am"},

"PROJECT":{"PROJECT_TITLE":"Dietary composition analysis studies","PROJECT_TYPE":"Untargeted metabolomics analysis with two diets","PROJECT_SUMMARY":"Dietary patterns and psychosocial factors, ubiquitous part of modern lifestyle, critically shape the gut microbiota and human health. However, it remains obscure how dietary and psychosocial inputs coordinately modulate the gut microbiota and host impact. Here, we show that dietary raffinose metabolism to fructose couples stress-induced gut microbial remodeling to intestinal stem cells (ISC) renewal and epithelial homeostasis. Chow diet (CD) and purified diet (PD) confer distinct vulnerability to gut epithelial injury, microbial alternation and ISC dysfunction in chronically restrained mice. CD preferably enriches Lactobacillus reuteri, and its colonization is sufficient to rescue stress-triggered epithelial injury.","INSTITUTE":"China Pharmaceutical University","DEPARTMENT":"School of Medicine","LABORATORY":"metabonomics","LAST_NAME":"Yunalong","FIRST_NAME":"Hou","ADDRESS":"Nanjing, Jiangsu","EMAIL":"jian2103@163.com","PHONE":"18851105337"},

"STUDY":{"STUDY_TITLE":"Dietary composition analysis of chow diet and purified diet using untargeted metabonomics","STUDY_SUMMARY":"Dietary patterns and psychosocial factors, ubiquitous part of modern lifestyle, critically shape the gut microbiota and human health. However, it remains obscure how dietary and psychosocial inputs coordinately modulate the gut microbiota and host impact. Here, we show that dietary raffinose metabolism to fructose couples stress-induced gut microbial remodeling to intestinal stem cells (ISC) renewal and epithelial homeostasis. Chow diet (CD) and purified diet (PD) confer distinct vulnerability to gut epithelial injury, microbial alternation and ISC dysfunction in chronically restrained mice. CD preferably enriches Lactobacillus reuteri, and its colonization is sufficient to rescue stress-triggered epithelial injury.","INSTITUTE":"China Pharmaceutical University","DEPARTMENT":"School of Medicine","LABORATORY":"metabonomics","LAST_NAME":"Yuanlong","FIRST_NAME":"Hou","ADDRESS":"Nanjing, Jiangsu","EMAIL":"jian2103@163.com","PHONE":"86-18851105337"},

"SUBJECT":{"SUBJECT_TYPE":"Food item"},
"SUBJECT_SAMPLE_FACTORS":[
{
"Subject ID":"-",
"Sample ID":"PD1",
"Factors":{"Diet":"Purified"},
"Additional sample data":{"RAW_FILE_NAME":"PD1"}
},
{
"Subject ID":"-",
"Sample ID":"PD2",
"Factors":{"Diet":"Purified"},
"Additional sample data":{"RAW_FILE_NAME":"PD2"}
},
{
"Subject ID":"-",
"Sample ID":"PD3",
"Factors":{"Diet":"Purified"},
"Additional sample data":{"RAW_FILE_NAME":"PD3"}
},
{
"Subject ID":"-",
"Sample ID":"PD4",
"Factors":{"Diet":"Purified"},
"Additional sample data":{"RAW_FILE_NAME":"PD4"}
},
{
"Subject ID":"-",
"Sample ID":"CD1",
"Factors":{"Diet":"Chow"},
"Additional sample data":{"RAW_FILE_NAME":"CD1"}
},
{
"Subject ID":"-",
"Sample ID":"CD2",
"Factors":{"Diet":"Chow"},
"Additional sample data":{"RAW_FILE_NAME":"CD2"}
},
{
"Subject ID":"-",
"Sample ID":"CD3",
"Factors":{"Diet":"Chow"},
"Additional sample data":{"RAW_FILE_NAME":"CD3"}
}
],
"COLLECTION":{"COLLECTION_SUMMARY":"Purified diet and chow diet","SAMPLE_TYPE":"Diet","STORAGE_CONDITIONS":"4℃"},

"TREATMENT":{"TREATMENT_SUMMARY":"Diet pellets (30 mg) were weighted by adding 400 µL of methanol (pre-cooled at -20℃), vortexed for 60 s, and then centrifuged for 10 min at 13,000 g, 4℃. The supernatant was evaporated to dryness under vacuum, reconstituted with 150 μL of 2-chlorophenyalanine (4ppm) methanol aqueous solution."},

"SAMPLEPREP":{"SAMPLEPREP_SUMMARY":"Diet pellets (30 mg) come from lab","PROCESSING_STORAGE_CONDITIONS":"4℃","EXTRACT_STORAGE":"4℃"},

"CHROMATOGRAPHY":{"CHROMATOGRAPHY_TYPE":"Reversed phase","INSTRUMENT_NAME":"UltiMate 3000","COLUMN_NAME":"Waters Acquity UPLC HSS T3 (150×2.1 mm,1.8 µm)"},

"ANALYSIS":{"ANALYSIS_TYPE":"MS"},

"MS":{"INSTRUMENT_NAME":"Q Exactive Focus","INSTRUMENT_TYPE":"Orbitrap","MS_TYPE":"ESI","ION_MODE":"UNSPECIFIED","MS_COMMENTS":"Data dependent acquisition The Progenesis QI MetaboAnalyst 3.0"},

"MS_METABOLITE_DATA":{
"Units":"peak area",

"Data":[{"Metabolite":"Alanine","PD1":"3738351.177","PD2":"4107228.975","PD3":"3297035.981","PD4":"4215511.609","CD1":"47561055.41","CD2":"47150449.19","CD3":"44168781.33"},{"Metabolite":"Valerolactam","PD1":"10572517.86","PD2":"9452215.072","PD3":"10639758.29","PD4":"10071073.82","CD1":"459256213.7","CD2":"456358058.6","CD3":"445241753.8"},{"Metabolite":"2-Ketobutyrate","PD1":"2835833.256","PD2":"1228233.467","PD3":"3572553.483","PD4":"3372488.827","CD1":"15050121.17","CD2":"16774622.88","CD3":"18175033.75"},{"Metabolite":"Cadaverine","PD1":"504672.3525","PD2":"452697.8617","PD3":"488199.6649","PD4":"617791.5369","CD1":"19799623.44","CD2":"21196971.16","CD3":"23497347.28"},{"Metabolite":"Gamma-Aminobutyrate","PD1":"8393844.568","PD2":"7962231.293","PD3":"8262938.906","PD4":"7582228.926","CD1":"81125551.06","CD2":"80041169.47","CD3":"72273282.94"},{"Metabolite":"3-Hydroxybutyrate","PD1":"180015144.2","PD2":"171821964.3","PD3":"195805564.4","PD4":"170185394.9","CD1":"241594119.1","CD2":"237387324.8","CD3":"237437037.1"},{"Metabolite":"Benzaldehyde","PD1":"1916033.188","PD2":"1796364.323","PD3":"1786544.244","PD4":"1740931.046","CD1":"11365625.5","CD2":"11535317.12","CD3":"11668767.67"},{"Metabolite":"Pyrrole-2-Carboxylate","PD1":"46148301.53","PD2":"46131191.02","PD3":"48532972.62","PD4":"42973446.77","CD1":"36703299.17","CD2":"37535400.91","CD3":"36875004.67"},{"Metabolite":"Cytosine","PD1":"2272583.497","PD2":"2140945.566","PD3":"1985489.836","PD4":"1974970.083","CD1":"58690632.07","CD2":"56944298.15","CD3":"55460404.63"},{"Metabolite":"Pantolactone","PD1":"1936375.584","PD2":"1811088.838","PD3":"1933854.233","PD4":"2031960.995","CD1":"6176766.033","CD2":"6745474.019","CD3":"6750175.001"},{"Metabolite":"Valine","PD1":"6722347.31","PD2":"1209524.048","PD3":"1467997.046","PD4":"1219850.115","CD1":"45926257.59","CD2":"44624092.82","CD3":"45270445.17"},{"Metabolite":"Fumarate","PD1":"3091292.307","PD2":"2781903.828","PD3":"3012013.697","PD4":"2893644.792","CD1":"18195495.2","CD2":"17141390.45","CD3":"17785319.06"},{"Metabolite":"Indole","PD1":"41843385.39","PD2":"40295171.91","PD3":"43581797.06","PD4":"40933065.72","CD1":"488738581.4","CD2":"506533218.2","CD3":"508030673.1"},{"Metabolite":"Niacinamide","PD1":"57323284.5","PD2":"33732407.49","PD3":"7890248.612","PD4":"8936853.621","CD1":"4256698120","CD2":"3760904093","CD3":"3456707759"},{"Metabolite":"Thymine","PD1":"48856325.57","PD2":"8011894.51","PD3":"46593947.1","PD4":"7895646.688","CD1":"128223735.3","CD2":"126953482.7","CD3":"124433217.4"},{"Metabolite":"Pyroglutamate","PD1":"16505943.51","PD2":"16048475.98","PD3":"18442871.4","PD4":"15733873.03","CD1":"783682960.4","CD2":"731409644","CD3":"758096381.1"},{"Metabolite":"Quinoline","PD1":"16395408.74","PD2":"24578848.01","PD3":"9774006.57","PD4":"19875068.08","CD1":"28119862.35","CD2":"33369392.62","CD3":"32172338.71"},{"Metabolite":"Pipecolate","PD1":"17838303.09","PD2":"11102918.96","PD3":"11483917.63","PD4":"13777313.54","CD1":"2273885102","CD2":"2291653849","CD3":"1602440470"},{"Metabolite":"Leucine","PD1":"72642593.59","PD2":"28604772.12","PD3":"17619819.66","PD4":"48607148.72","CD1":"206046582.2","CD2":"298693965.9","CD3":"289401869"},{"Metabolite":"Cinnamate","PD1":"2089444.46","PD2":"2077121.648","PD3":"2065600.211","PD4":"1834315.785","CD1":"26548186.4","CD2":"24581413.26","CD3":"24730737.56"},{"Metabolite":"4-Hydroxy-D-Proline","PD1":"9460114.425","PD2":"10615851.59","PD3":"11862202.47","PD4":"9609508.413","CD1":"6311712.52","CD2":"4641765.781","CD3":"4312303.757"},{"Metabolite":"N-Acetyl-L-Alanine","PD1":"2811374.955","PD2":"2746175.632","PD3":"2682514.152","PD4":"2566526.011","CD1":"11181938.52","CD2":"11781052.28","CD3":"10490474.74"},{"Metabolite":"Isoleucine","PD1":"71788325.23","PD2":"81641149.8","PD3":"59746671.1","PD4":"122824647.7","CD1":"2102230001","CD2":"1995144161","CD3":"1988269663"},{"Metabolite":"Malate","PD1":"655284.3273","PD2":"564353.0709","PD3":"499591.5853","PD4":"556664.1453","CD1":"27954690.04","CD2":"27579221.36","CD3":"31154849.46"},{"Metabolite":"Adenine","PD1":"108751108.7","PD2":"115529485.2","PD3":"105002031.2","PD4":"106904123.2","CD1":"246226341","CD2":"259624244.4","CD3":"204492669.6"},{"Metabolite":"Threonate","PD1":"7380628.963","PD2":"7828704.331","PD3":"6402994.877","PD4":"7102813.955","CD1":"149464676.7","CD2":"181673226.5","CD3":"168140459"},{"Metabolite":"Urocanate","PD1":"3521760.597","PD2":"4363044.502","PD3":"3957324.748","PD4":"5162677.261","CD1":"5990322.252","CD2":"6802906.003","CD3":"5626597.676"},{"Metabolite":"Hypoxanthine","PD1":"9024286.014","PD2":"8665449.689","PD3":"8798006.196","PD4":"9930382.995","CD1":"1301867742","CD2":"1165946255","CD3":"1174883656"},{"Metabolite":"2-Methoxyhydroquinone","PD1":"6278608.642","PD2":"5968127.117","PD3":"1627874.742","PD4":"1479579.455","CD1":"18586645.4","CD2":"18148443.68","CD3":"17823614.67"},{"Metabolite":"Caprylate","PD1":"3569605.467","PD2":"3639728.214","PD3":"3833184.402","PD4":"3662206.339","CD1":"1773561.731","CD2":"1190923.27","CD3":"1183962.703"},{"Metabolite":"Coumarin","PD1":"28464526.18","PD2":"29364393.07","PD3":"33569056.1","PD4":"29675459.7","CD1":"527101644.6","CD2":"483742002.2","CD3":"553963886.6"},{"Metabolite":"Glutamate","PD1":"3166125.015","PD2":"4514682.567","PD3":"3036720.484","PD4":"3361319.604","CD1":"3658004340","CD2":"3820384108","CD3":"2761821457"},{"Metabolite":"Lysine","PD1":"4360303.166","PD2":"3451052.01","PD3":"4318364.826","PD4":"3723268.778","CD1":"117102988.9","CD2":"116667826","CD3":"89322553.5"},{"Metabolite":"Ribose","PD1":"24998684.54","PD2":"32023103.31","PD3":"37005960.44","PD4":"23979361.42","CD1":"144793670.7","CD2":"118537380.1","CD3":"98950109.25"},{"Metabolite":"Methionine","PD1":"1160898.4","PD2":"1201612.93","PD3":"1451206.997","PD4":"1276247.083","CD1":"65667629.91","CD2":"76153669.23","CD3":"73036299.04"},{"Metabolite":"Guanine","PD1":"4237756.033","PD2":"4234101.554","PD3":"4761603.568","PD4":"4302172.645","CD1":"63070388.08","CD2":"72490237.51","CD3":"66353454.32"},{"Metabolite":"Lyxose","PD1":"60797111.85","PD2":"64138150.26","PD3":"61406297.27","PD4":"58136927.96","CD1":"43940222.07","CD2":"45543971.8","CD3":"44896378.2"},{"Metabolite":"Arabitol","PD1":"3542946.152","PD2":"3321101.606","PD3":"3086274.553","PD4":"3749602.951","CD1":"68833324.39","CD2":"73649134.73","CD3":"70420424.34"},{"Metabolite":"Xanthine","PD1":"14222998.13","PD2":"15544133.44","PD3":"16243581.29","PD4":"14762851.34","CD1":"522842286.2","CD2":"480155000.4","CD3":"494484903.3"},{"Metabolite":"Gentisate","PD1":"60.29200215","PD2":"60.29200215","PD3":"60.29200215","PD4":"60.29200215","CD1":"258321094.3","CD2":"276742801.6","CD3":"65997648.03"},{"Metabolite":"Oxoadipate","PD1":"138059257.6","PD2":"139951597.8","PD3":"111471619.9","PD4":"154348975.7","CD1":"91605979.03","CD2":"59389926.99","CD3":"71646439.43"},{"Metabolite":"Tryptamine","PD1":"6536332.495","PD2":"6470254.666","PD3":"6675788.934","PD4":"6494557.621","CD1":"34288884.49","CD2":"34645002.01","CD3":"33413727.99"},{"Metabolite":"Carnitine","PD1":"12943149.61","PD2":"13023682.69","PD3":"13293973.64","PD4":"13234883.5","CD1":"58275282.24","CD2":"59349122.3","CD3":"52687196.42"},{"Metabolite":"Pterin","PD1":"13105146.42","PD2":"14248703.89","PD3":"16349110.45","PD4":"14403532.45","CD1":"6879515.06","CD2":"7016439.807","CD3":"6922277.637"},{"Metabolite":"7-Methylguanine","PD1":"172086.6304","PD2":"156319.377","PD3":"187481.8327","PD4":"217537.2394","CD1":"3867111.476","CD2":"3802639.977","CD3":"3794755.973"},{"Metabolite":"Beta-Homomethionine","PD1":"1162489.326","PD2":"1104800.585","PD3":"5559120.148","PD4":"1123000.363","CD1":"18923357.71","CD2":"20850211.95","CD3":"18592494.63"},{"Metabolite":"Coumarate","PD1":"8912113.374","PD2":"9261330.303","PD3":"10036673.89","PD4":"9095491.382","CD1":"7198996.001","CD2":"7469340.423","CD3":"7621757.267"},{"Metabolite":"Methionine S-Oxide","PD1":"15146313.23","PD2":"8162029.001","PD3":"28034906.78","PD4":"11570937.86","CD1":"212711253.8","CD2":"196674745.4","CD3":"246040268.6"},{"Metabolite":"Phenylalanine","PD1":"190714908.5","PD2":"197199123.4","PD3":"204171993.4","PD4":"196803406.3","CD1":"3098768897","CD2":"2888155627","CD3":"2886758738"},{"Metabolite":"Vanillate","PD1":"2715751.383","PD2":"2571501.244","PD3":"3034873.961","PD4":"2711326.722","CD1":"9047976.84","CD2":"8986605.197","CD3":"9281045.54"},{"Metabolite":"4-Hydroxyphenylglycine","PD1":"602499.2479","PD2":"1185946.87","PD3":"1921310.794","PD4":"1225966.113","CD1":"11628908.99","CD2":"12922640.62","CD3":"15072060.76"},{"Metabolite":"Stachyose","PD1":"66475308.77","PD2":"56106385.25","PD3":"70654751.81","PD4":"64645949.06","CD1":"136962579.6","CD2":"98642021.93","CD3":"107652508.7"},{"Metabolite":"Quinaldate","PD1":"1943094.702","PD2":"1337998.155","PD3":"1607383.079","PD4":"1541496.592","CD1":"4527414.998","CD2":"3931208.461","CD3":"3493063.386"},{"Metabolite":"N-Formyl-L-Methionine","PD1":"411747.4814","PD2":"375741.5149","PD3":"308566.342","PD4":"391800.9367","CD1":"4649448.514","CD2":"5158689.399","CD3":"5046063.895"},{"Metabolite":"Guanidinosuccinate","PD1":"52446553.23","PD2":"21784077.76","PD3":"14852871.84","PD4":"29956293.93","CD1":"105181862.4","CD2":"102930150.1","CD3":"102026604.3"},{"Metabolite":"Coniferyl Aldehyde","PD1":"1584879.132","PD2":"1564929.584","PD3":"1650837.242","PD4":"1443209.007","CD1":"3067067.614","CD2":"3638252.924","CD3":"3597957.162"},{"Metabolite":"Theophylline","PD1":"14209363.21","PD2":"12843105.39","PD3":"13184510.11","PD4":"12969522.7","CD1":"7950943.884","CD2":"1918299.075","CD3":"1874013.395"},{"Metabolite":"Tyrosine","PD1":"17383952.38","PD2":"16187984.47","PD3":"18383441.9","PD4":"16967206.26","CD1":"177995517.8","CD2":"179668803.1","CD3":"168799473.6"},{"Metabolite":"Sorbitol","PD1":"297026868","PD2":"164683604.8","PD3":"219554817.8","PD4":"262855072.8","CD1":"913353616.2","CD2":"993514887","CD3":"907491720.2"},{"Metabolite":"Sebacate","PD1":"3530483.989","PD2":"2253051.096","PD3":"2406387.587","PD4":"2126310.149","CD1":"6936735.632","CD2":"11117931.71","CD3":"10216004.51"},{"Metabolite":"Indoleacrylate","PD1":"365175.2615","PD2":"304530.7331","PD3":"289521.8834","PD4":"321948.1542","CD1":"10788490.55","CD2":"11430759.26","CD3":"10906696.11"},{"Metabolite":"Azelaic acid","PD1":"22383843.62","PD2":"24583850.42","PD3":"22203905.61","PD4":"24959056.48","CD1":"85615740.21","CD2":"84634075.62","CD3":"83024247.99"},{"Metabolite":"Alpha-Acetyllysine","PD1":"80333351.54","PD2":"83131406.86","PD3":"91506486.4","PD4":"83283447.26","CD1":"17968905212","CD2":"18531686515","CD3":"18542487513"},{"Metabolite":"Glycylleucine","PD1":"1322673.997","PD2":"1561324.219","PD3":"1082332.338","PD4":"1190817.348","CD1":"46113458.25","CD2":"43238428.56","CD3":"40444326.43"},{"Metabolite":"N-Acetylglutamate","PD1":"17760612.16","PD2":"20267361.68","PD3":"24633249.59","PD4":"18976317.61","CD1":"11703855.14","CD2":"11482966.47","CD3":"11921447.02"},{"Metabolite":"N-Acetyl-DL-Methionine","PD1":"658771.8917","PD2":"821832.9789","PD3":"151446.8679","PD4":"940615.1564","CD1":"20494286.68","CD2":"17929896.02","CD3":"19277392.14"},{"Metabolite":"Daidzin","PD1":"263582.0268","PD2":"247055.9071","PD3":"234615.8994","PD4":"2403.396568","CD1":"832577.8493","CD2":"594589.2556","CD3":"584831.942"},{"Metabolite":"Citrate","PD1":"1369684825","PD2":"1430630733","PD3":"1500360580","PD4":"1456216580","CD1":"424545372.3","CD2":"318429884.9","CD3":"379555088.4"},{"Metabolite":"Phenylacetylglycine","PD1":"5531173.17","PD2":"5661916.073","PD3":"5096500.327","PD4":"5885321.371","CD1":"20937475.79","CD2":"17963330.48","CD3":"19868880.1"},{"Metabolite":"Ferulate","PD1":"5453169.969","PD2":"5147177.827","PD3":"5854033.303","PD4":"5320100.243","CD1":"71539318.92","CD2":"71431914.61","CD3":"65454671.33"},{"Metabolite":"Gluconate","PD1":"379609.339","PD2":"440364.769","PD3":"338838.4115","PD4":"387103.6208","CD1":"190248196.1","CD2":"229161988.3","CD3":"203960443.9"},{"Metabolite":"Gulonate","PD1":"466329.0863","PD2":"498470.5615","PD3":"501093.3769","PD4":"609324.4229","CD1":"2620443.547","CD2":"2880523.686","CD3":"2258337.949"},{"Metabolite":"Mannonate","PD1":"516444.2179","PD2":"527328.2034","PD3":"707215.5761","PD4":"504053.3769","CD1":"1041837.582","CD2":"959874.0126","CD3":"936744.4253"},{"Metabolite":"Dopa","PD1":"14944423.29","PD2":"15304719.57","PD3":"21418424.88","PD4":"15972014.07","CD1":"1944309.434","CD2":"6113568.149","CD3":"6006136.627"},{"Metabolite":"Ala-Ile","PD1":"373997.9665","PD2":"411835.241","PD3":"195739.6998","PD4":"523360.9292","CD1":"6346175.171","CD2":"7110190.095","CD3":"6116684.304"},{"Metabolite":"Maltotriose","PD1":"95313988.87","PD2":"74906620.27","PD3":"110008205.2","PD4":"91903490.73","CD1":"266757084.4","CD2":"255797737.8","CD3":"257320561.7"},{"Metabolite":"Leucyl-Alanine","PD1":"2068572.318","PD2":"2296566.841","PD3":"2420555.642","PD4":"2219353.155","CD1":"13475747.6","CD2":"11589698.99","CD3":"13823111.87"},{"Metabolite":"Tryptophan","PD1":"67107.63133","PD2":"46000.05766","PD3":"55098.99218","PD4":"111209.3157","CD1":"25024912.47","CD2":"25517250.46","CD3":"25164776.64"},{"Metabolite":"Kynurenine","PD1":"32060051.38","PD2":"40170010.86","PD3":"32547759.41","PD4":"37898981.94","CD1":"15885834.48","CD2":"15851401.92","CD3":"16861395.05"},{"Metabolite":"Sinapate","PD1":"3578277.454","PD2":"3713859.607","PD3":"3273895.193","PD4":"3558501.665","CD1":"10359433.93","CD2":"9419276.399","CD3":"10047870.94"},{"Metabolite":"Astragalin","PD1":"31015.85688","PD2":"1918237.978","PD3":"2599.218857","PD4":"1881380.722","CD1":"4935676.328","CD2":"3764039.816","CD3":"3244725.889"},{"Metabolite":"Myristoleate","PD1":"19446464.46","PD2":"21804953.43","PD3":"19069160.33","PD4":"21457777.74","CD1":"6006743.17","CD2":"957712.1798","CD3":"4784783.595"},{"Metabolite":"Dodecanedioate","PD1":"115027.0343","PD2":"103259.4288","PD3":"103568.815","PD4":"113645.0048","CD1":"3839342.818","CD2":"3697296.558","CD3":"4111757.982"},{"Metabolite":"Myristic acid","PD1":"8387078.863","PD2":"8724236.77","PD3":"9063625.984","PD4":"8496805.648","CD1":"6927132.021","CD2":"7145829.876","CD3":"6930174.62"},{"Metabolite":"Butyryl-L-Carnitine","PD1":"1200678.429","PD2":"1271381.131","PD3":"1223670.179","PD4":"1241855.671","CD1":"8128544.028","CD2":"7583699.412","CD3":"7953078.804"},{"Metabolite":"N-Lactoyl-Phenylalanine","PD1":"722236.0418","PD2":"1006710.693","PD3":"950973.7308","PD4":"943692.9746","CD1":"12281555.19","CD2":"11409692.09","CD3":"11205785.48"},{"Metabolite":"Uridine","PD1":"498567.5283","PD2":"443610.0136","PD3":"450468.02","PD4":"474968.3142","CD1":"131872982.4","CD2":"119271011.3","CD3":"117904011.3"},{"Metabolite":"4-Oxododecanedioic acid","PD1":"1041138.686","PD2":"1087074.571","PD3":"992758.409","PD4":"1096173.09","CD1":"9643837.803","CD2":"9237292.804","CD3":"9265129.846"},{"Metabolite":"3-Hydroxy-Tetradecanoic 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acid"},{"metabolite_name":"Alpha-Acetyllysine"},{"metabolite_name":"Glycylleucine"},{"metabolite_name":"N-Acetylglutamate"},{"metabolite_name":"N-Acetyl-DL-Methionine"},{"metabolite_name":"Daidzin"},{"metabolite_name":"Citrate"},{"metabolite_name":"Phenylacetylglycine"},{"metabolite_name":"Ferulate"},{"metabolite_name":"Gluconate"},{"metabolite_name":"Gulonate"},{"metabolite_name":"Mannonate"},{"metabolite_name":"Dopa"},{"metabolite_name":"Ala-Ile"},{"metabolite_name":"Maltotriose"},{"metabolite_name":"Leucyl-Alanine"},{"metabolite_name":"Tryptophan"},{"metabolite_name":"Kynurenine"},{"metabolite_name":"Sinapate"},{"metabolite_name":"Astragalin"},{"metabolite_name":"Myristoleate"},{"metabolite_name":"Dodecanedioate"},{"metabolite_name":"Myristic acid"},{"metabolite_name":"Butyryl-L-Carnitine"},{"metabolite_name":"N-Lactoyl-Phenylalanine"},{"metabolite_name":"Uridine"},{"metabolite_name":"4-Oxododecanedioic acid"},{"metabolite_name":"3-Hydroxy-Tetradecanoic acid"},{"metabolite_name":"Cytidine"},{"metabolite_name":"N-Acetyl-DL-Tryptophan"},{"metabolite_name":"Phe-Pro"},{"metabolite_name":"Glycitin"},{"metabolite_name":"2-Deoxyadenosine"},{"metabolite_name":"5,7-Dihydroxyflavone"},{"metabolite_name":"Palmitoleic acid"},{"metabolite_name":"Naringenin"},{"metabolite_name":"Glu-Leu"},{"metabolite_name":"Thiamine"},{"metabolite_name":"Valyl-Phenylalanine"},{"metabolite_name":"2-Deoxyguanosine"},{"metabolite_name":"Adenosine"},{"metabolite_name":"Hesperetin"},{"metabolite_name":"Inosine"},{"metabolite_name":"12-OPDA"},{"metabolite_name":"Stearidonic acid"},{"metabolite_name":"Linoleic acid"},{"metabolite_name":"Guanosine"},{"metabolite_name":"Hexadecanedioic acid"},{"metabolite_name":"13-L-Hydroperoxylinoleic acid"},{"metabolite_name":"Gingerol"},{"metabolite_name":"13S-Hydroxyoctadecadienoic acid"},{"metabolite_name":"9,10-Epoxyoctadecenoic acid"},{"metabolite_name":"Nonadecanoic acid"},{"metabolite_name":"2-O-Methylguanosine"},{"metabolite_name":"Arachidonic acid"},{"metabolite_name":"dCMP"},{"metabolite_name":"Ribose-1,5-Bisphosphate"},{"metabolite_name":"9,10-DHOME"},{"metabolite_name":"Malvidin"},{"metabolite_name":"15-Deoxy-D-12,14-PGJ2"},{"metabolite_name":"Alpha-Linolenoyl Ethanolamide"},{"metabolite_name":"Cellobiose"},{"metabolite_name":"Cyclic AMP"},{"metabolite_name":"3-AMP"},{"metabolite_name":"5-O-Beta-D-Glucosylpyridoxine"},{"metabolite_name":"5,6-DiHETE"},{"metabolite_name":"5,6-DHET"},{"metabolite_name":"Trehalose"},{"metabolite_name":"MG(18:2/0:0/0:0)"},{"metabolite_name":"2-Linoleoyl Glycerol"},{"metabolite_name":"Rosmarinate"},{"metabolite_name":"N-Oleoyl-Serine"},{"metabolite_name":"N-Arachidonoyl-Alanine"},{"metabolite_name":"S-Adenosylhomocysteine"},{"metabolite_name":"Acetyl-Maltose"},{"metabolite_name":"Deoxycholic acid"},{"metabolite_name":"Cosmosiin"},{"metabolite_name":"Oleanoic acid"},{"metabolite_name":"Folic acid"},{"metabolite_name":"PC(14:0/0:0)"},{"metabolite_name":"Raffinose"},{"metabolite_name":"1-Heptadecanoyl-sn-Glycero-3-Phosphocholine"},{"metabolite_name":"6-Malonylgenistin"},{"metabolite_name":"Syringaresinol O-Beta-D-Glucoside"},{"metabolite_name":"Maltotetraose"},{"metabolite_name":"Maltohexaose"}]
}

}