{
"METABOLOMICS WORKBENCH":{"STUDY_ID":"ST002452","ANALYSIS_ID":"AN004008","VERSION":"1","CREATED_ON":"January 30, 2023, 7:02 am"},

"PROJECT":{"PROJECT_TITLE":"Frontotemporal Dementia Human Brain Lipidomics","PROJECT_SUMMARY":"Frontotemporal dementia (FTD) lipidomic study of human brain from cases with GRN or C9orf72 mutations or controls. We aimed to determine how inherited mutations that cause FTD affect the brain lipidome. Both heterozygous GRN mutations and C9orf72 repeat expansions cause FTD with TDP-43 pathology, but GRN mutation carriers appear to have significant white matter pathology as seen by MRI. Our study uncovered significant loss of myelin sphingolipids in the heavily affected superior frontal white matter in both FTD groups, but GRN carriers show more severe myelin attrition than C9orf72 repeat expansion carriers. GRN carriers also showed selective increase in cholesterol esters and sphingosine in the less affected superior parietal white matter.","INSTITUTE":"The University of Sydney","LAST_NAME":"Don","FIRST_NAME":"Anthony","ADDRESS":"Office 3217, D17 Charles Perkins Centre, Camperdown, NSW, 2006, Australia","EMAIL":"anthony.don@sydney.edu.au","PHONE":"+61286275578"},

"STUDY":{"STUDY_TITLE":"Lipidomic analysis of human brain from frontotemporal dementia cases of with GRN and C9orf72 mutations","STUDY_SUMMARY":"Lipidomic analysis carried out on postmortem human brain tissue from cases with FTD carrying inherited mutations in the GRN gene, or repeat expansions in the C9orf72 gene, and age-matched control cases. Tissue was sampled from the heavily affected superior frontal grey and white matter, and less heavily affected superior parietal grey and white matter.","INSTITUTE":"The University of Sydney","LAST_NAME":"Don","FIRST_NAME":"Anthony","ADDRESS":"Office 3217, D17 Charles Perkins Centre, Camperdown, NSW, 2006, Australia","EMAIL":"anthony.don@sydney.edu.au","PHONE":"+61286275578","NUM_GROUPS":"3","TOTAL_SUBJECTS":"28","NUM_MALES":"13","NUM_FEMALES":"15"},

"SUBJECT":{"SUBJECT_TYPE":"Human","SUBJECT_SPECIES":"Homo sapiens","TAXONOMY_ID":"9606"},
"SUBJECT_SAMPLE_FACTORS":[
{
"Subject ID":"-",
"Sample ID":"366_SFG_GM",
"Factors":{"Genotype":"Control","Brain region":"SFG_GM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"366_SFG-GM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"384_SFG_GM",
"Factors":{"Genotype":"Control","Brain region":"SFG_GM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"384_SFG-GM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"393_SFG_GM",
"Factors":{"Genotype":"Control","Brain region":"SFG_GM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"393_SFG-GM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"518_SFG_GM",
"Factors":{"Genotype":"Control","Brain region":"SFG_GM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"518_SFG-GM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"613_SFG_GM",
"Factors":{"Genotype":"Control","Brain region":"SFG_GM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"613_SFG-GM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"662_SFG_GM",
"Factors":{"Genotype":"Control","Brain region":"SFG_GM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"662_SFG-GM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"688_SFG_GM",
"Factors":{"Genotype":"Control","Brain region":"SFG_GM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"688_SFG-GM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"758_SFG_GM",
"Factors":{"Genotype":"Control","Brain region":"SFG_GM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"758_SFG-GM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"831_SFG_GM",
"Factors":{"Genotype":"Control","Brain region":"SFG_GM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"831_SFG-GM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"851_SFG_GM",
"Factors":{"Genotype":"Control","Brain region":"SFG_GM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"851_SFG-GM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"925_SFG_GM",
"Factors":{"Genotype":"Control","Brain region":"SFG_GM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"925_SFG-GM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"436_SFG_GM",
"Factors":{"Genotype":"C9orf72","Brain region":"SFG_GM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"436_SFG-GM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"448_SFG_GM",
"Factors":{"Genotype":"C9orf72","Brain region":"SFG_GM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"448_SFG-GM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"526_SFG_GM",
"Factors":{"Genotype":"C9orf72","Brain region":"SFG_GM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"526_SFG-GM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"625_SFG_GM",
"Factors":{"Genotype":"C9orf72","Brain region":"SFG_GM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"625_SFG-GM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"729_SFG_GM",
"Factors":{"Genotype":"C9orf72","Brain region":"SFG_GM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"729_SFG-GM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"732_SFG_GM",
"Factors":{"Genotype":"C9orf72","Brain region":"SFG_GM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"732_SFG-GM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"736_SFG_GM",
"Factors":{"Genotype":"C9orf72","Brain region":"SFG_GM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"736_SFG-GM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"754_SFG_GM",
"Factors":{"Genotype":"C9orf72","Brain region":"SFG_GM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"754_SFG-GM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"785_SFG_GM",
"Factors":{"Genotype":"C9orf72","Brain region":"SFG_GM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"785_SFG-GM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"806_SFG_GM",
"Factors":{"Genotype":"C9orf72","Brain region":"SFG_GM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"806_SFG-GM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"918_SFG_GM",
"Factors":{"Genotype":"C9orf72","Brain region":"SFG_GM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"918_SFG-GM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"486_SFG_GM",
"Factors":{"Genotype":"GRN","Brain region":"SFG_GM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"486_SFG-GM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"531_SFG_GM",
"Factors":{"Genotype":"GRN","Brain region":"SFG_GM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"531_SFG-GM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"540_SFG_GM",
"Factors":{"Genotype":"GRN","Brain region":"SFG_GM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"540_SFG-GM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"677_SFG_GM",
"Factors":{"Genotype":"GRN","Brain region":"SFG_GM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"677_SFG-GM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"731_SFG_GM",
"Factors":{"Genotype":"GRN","Brain region":"SFG_GM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"731_SFG-GM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"738_SFG_GM",
"Factors":{"Genotype":"GRN","Brain region":"SFG_GM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"738_SFG-GM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"366_n_SFG_GM",
"Factors":{"Genotype":"Control","Brain region":"SFG_GM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"366_SFG-GM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"384_n_SFG_GM",
"Factors":{"Genotype":"Control","Brain region":"SFG_GM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"384_SFG-GM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"393_n_SFG_GM",
"Factors":{"Genotype":"Control","Brain region":"SFG_GM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"393_SFG-GM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"518_n_SFG_GM",
"Factors":{"Genotype":"Control","Brain region":"SFG_GM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"518_SFG-GM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"613_n_SFG_GM",
"Factors":{"Genotype":"Control","Brain region":"SFG_GM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"613_SFG-GM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"662_n_SFG_GM",
"Factors":{"Genotype":"Control","Brain region":"SFG_GM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"662_SFG-GM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"688_n_SFG_GM",
"Factors":{"Genotype":"Control","Brain region":"SFG_GM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"688_SFG-GM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"758_n_SFG_GM",
"Factors":{"Genotype":"Control","Brain region":"SFG_GM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"758_SFG-GM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"831_n_SFG_GM",
"Factors":{"Genotype":"Control","Brain region":"SFG_GM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"831_SFG-GM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"851_n_SFG_GM",
"Factors":{"Genotype":"Control","Brain region":"SFG_GM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"851_SFG-GM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"925_n_SFG_GM",
"Factors":{"Genotype":"Control","Brain region":"SFG_GM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"925_SFG-GM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"436_n_SFG_GM",
"Factors":{"Genotype":"C9orf72","Brain region":"SFG_GM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"436_SFG-GM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"448_n_SFG_GM",
"Factors":{"Genotype":"C9orf72","Brain region":"SFG_GM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"448_SFG-GM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"526_n_SFG_GM",
"Factors":{"Genotype":"C9orf72","Brain region":"SFG_GM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"526_SFG-GM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"625_n_SFG_GM",
"Factors":{"Genotype":"C9orf72","Brain region":"SFG_GM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"625_SFG-GM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"729_n_SFG_GM",
"Factors":{"Genotype":"C9orf72","Brain region":"SFG_GM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"729_SFG-GM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"732_n_SFG_GM",
"Factors":{"Genotype":"C9orf72","Brain region":"SFG_GM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"732_SFG-GM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"736_n_SFG_GM",
"Factors":{"Genotype":"C9orf72","Brain region":"SFG_GM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"736_SFG-GM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"754_n_SFG_GM",
"Factors":{"Genotype":"C9orf72","Brain region":"SFG_GM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"754_SFG-GM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"785_n_SFG_GM",
"Factors":{"Genotype":"C9orf72","Brain region":"SFG_GM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"785_SFG-GM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"806_n_SFG_GM",
"Factors":{"Genotype":"C9orf72","Brain region":"SFG_GM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"806_SFG-GM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"918_n_SFG_GM",
"Factors":{"Genotype":"C9orf72","Brain region":"SFG_GM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"918_SFG-GM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"486_n_SFG_GM",
"Factors":{"Genotype":"GRN","Brain region":"SFG_GM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"486_SFG-GM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"531_n_SFG_GM",
"Factors":{"Genotype":"GRN","Brain region":"SFG_GM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"531_SFG-GM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"540_n_SFG_GM",
"Factors":{"Genotype":"GRN","Brain region":"SFG_GM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"540_SFG-GM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"677_n_SFG_GM",
"Factors":{"Genotype":"GRN","Brain region":"SFG_GM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"677_SFG-GM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"731_n_SFG_GM",
"Factors":{"Genotype":"GRN","Brain region":"SFG_GM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"731_SFG-GM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"738_n_SFG_GM",
"Factors":{"Genotype":"GRN","Brain region":"SFG_GM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"738_SFG-GM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"366_SFG_WM",
"Factors":{"Genotype":"Control","Brain region":"SFG_WM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"366_SFG-WM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"384_SFG_WM",
"Factors":{"Genotype":"Control","Brain region":"SFG_WM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"384_SFG-WM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"393_SFG_WM",
"Factors":{"Genotype":"Control","Brain region":"SFG_WM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"393_SFG-WM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"518_SFG_WM",
"Factors":{"Genotype":"Control","Brain region":"SFG_WM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"518_SFG-WM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"613_SFG_WM",
"Factors":{"Genotype":"Control","Brain region":"SFG_WM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"613_SFG-WM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"662_SFG_WM",
"Factors":{"Genotype":"Control","Brain region":"SFG_WM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"662_SFG-WM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"688_SFG_WM",
"Factors":{"Genotype":"Control","Brain region":"SFG_WM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"688_SFG-WM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"758_SFG_WM",
"Factors":{"Genotype":"Control","Brain region":"SFG_WM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"758_SFG-WM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"831_SFG_WM",
"Factors":{"Genotype":"Control","Brain region":"SFG_WM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"831_SFG-WM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"851_SFG_WM",
"Factors":{"Genotype":"Control","Brain region":"SFG_WM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"851_SFG-WM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"925_SFG_WM",
"Factors":{"Genotype":"Control","Brain region":"SFG_WM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"925_SFG-WM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"436_SFG_WM",
"Factors":{"Genotype":"C9orf72","Brain region":"SFG_WM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"436_SFG-WM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"448_SFG_WM",
"Factors":{"Genotype":"C9orf72","Brain region":"SFG_WM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"448_SFG-WM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"526_SFG_WM",
"Factors":{"Genotype":"C9orf72","Brain region":"SFG_WM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"526_SFG-WM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"625_SFG_WM",
"Factors":{"Genotype":"C9orf72","Brain region":"SFG_WM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"625_SFG-WM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"729_SFG_WM",
"Factors":{"Genotype":"C9orf72","Brain region":"SFG_WM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"729_SFG-WM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"732_SFG_WM",
"Factors":{"Genotype":"C9orf72","Brain region":"SFG_WM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"732_SFG-WM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"736_SFG_WM",
"Factors":{"Genotype":"C9orf72","Brain region":"SFG_WM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"736_SFG-WM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"754_SFG_WM",
"Factors":{"Genotype":"C9orf72","Brain region":"SFG_WM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"754_SFG-WM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"785_SFG_WM",
"Factors":{"Genotype":"C9orf72","Brain region":"SFG_WM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"785_SFG-WM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"806_SFG_WM",
"Factors":{"Genotype":"C9orf72","Brain region":"SFG_WM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"806_SFG-WM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"918_SFG_WM",
"Factors":{"Genotype":"C9orf72","Brain region":"SFG_WM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"918_SFG-WM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"486_SFG_WM",
"Factors":{"Genotype":"GRN","Brain region":"SFG_WM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"486_SFG-WM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"531_SFG_WM",
"Factors":{"Genotype":"GRN","Brain region":"SFG_WM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"531_SFG-WM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"540_SFG_WM",
"Factors":{"Genotype":"GRN","Brain region":"SFG_WM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"540_SFG-WM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"677_SFG_WM",
"Factors":{"Genotype":"GRN","Brain region":"SFG_WM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"677_SFG-WM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"731_SFG_WM",
"Factors":{"Genotype":"GRN","Brain region":"SFG_WM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"731_SFG-WM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"738_SFG_WM",
"Factors":{"Genotype":"GRN","Brain region":"SFG_WM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"738_SFG-WM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"366_n_SFG_WM",
"Factors":{"Genotype":"Control","Brain region":"SFG_WM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"366_SFG-WM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"384_n_SFG_WM",
"Factors":{"Genotype":"Control","Brain region":"SFG_WM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"384_SFG-WM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"393_n_SFG_WM",
"Factors":{"Genotype":"Control","Brain region":"SFG_WM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"393_SFG-WM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"518_n_SFG_WM",
"Factors":{"Genotype":"Control","Brain region":"SFG_WM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"518_SFG-WM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"613_n_SFG_WM",
"Factors":{"Genotype":"Control","Brain region":"SFG_WM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"613_SFG-WM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"662_n_SFG_WM",
"Factors":{"Genotype":"Control","Brain region":"SFG_WM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"662_SFG-WM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"688_n_SFG_WM",
"Factors":{"Genotype":"Control","Brain region":"SFG_WM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"688_SFG-WM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"758_n_SFG_WM",
"Factors":{"Genotype":"Control","Brain region":"SFG_WM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"758_SFG-WM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"831_n_SFG_WM",
"Factors":{"Genotype":"Control","Brain region":"SFG_WM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"831_SFG-WM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"851_n_SFG_WM",
"Factors":{"Genotype":"Control","Brain region":"SFG_WM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"851_SFG-WM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"925_n_SFG_WM",
"Factors":{"Genotype":"Control","Brain region":"SFG_WM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"925_SFG-WM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"436_n_SFG_WM",
"Factors":{"Genotype":"C9orf72","Brain region":"SFG_WM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"436_SFG-WM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"448_n_SFG_WM",
"Factors":{"Genotype":"C9orf72","Brain region":"SFG_WM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"448_SFG-WM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"526_n_SFG_WM",
"Factors":{"Genotype":"C9orf72","Brain region":"SFG_WM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"526_SFG-WM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"625_n_SFG_WM",
"Factors":{"Genotype":"C9orf72","Brain region":"SFG_WM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"625_SFG-WM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"729_n_SFG_WM",
"Factors":{"Genotype":"C9orf72","Brain region":"SFG_WM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"729_SFG-WM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"732_n_SFG_WM",
"Factors":{"Genotype":"C9orf72","Brain region":"SFG_WM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"732_SFG-WM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"736_n_SFG_WM",
"Factors":{"Genotype":"C9orf72","Brain region":"SFG_WM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"736_SFG-WM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"754_n_SFG_WM",
"Factors":{"Genotype":"C9orf72","Brain region":"SFG_WM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"754_SFG-WM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"785_n_SFG_WM",
"Factors":{"Genotype":"C9orf72","Brain region":"SFG_WM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"785_SFG-WM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"806_n_SFG_WM",
"Factors":{"Genotype":"C9orf72","Brain region":"SFG_WM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"806_SFG-WM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"918_n_SFG_WM",
"Factors":{"Genotype":"C9orf72","Brain region":"SFG_WM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"918_SFG-WM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"486_n_SFG_WM",
"Factors":{"Genotype":"GRN","Brain region":"SFG_WM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"486_SFG-WM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"531_n_SFG_WM",
"Factors":{"Genotype":"GRN","Brain region":"SFG_WM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"531_SFG-WM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"540_n_SFG_WM",
"Factors":{"Genotype":"GRN","Brain region":"SFG_WM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"540_SFG-WM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"677_n_SFG_WM",
"Factors":{"Genotype":"GRN","Brain region":"SFG_WM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"677_SFG-WM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"731_n_SFG_WM",
"Factors":{"Genotype":"GRN","Brain region":"SFG_WM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"731_SFG-WM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"738_n_SFG_WM",
"Factors":{"Genotype":"GRN","Brain region":"SFG_WM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"738_SFG-WM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"366_SPC_GM",
"Factors":{"Genotype":"Control","Brain region":"SPC_GM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"366_SPC-GM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"384_SPC_GM",
"Factors":{"Genotype":"Control","Brain region":"SPC_GM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"384_SPC-GM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"393_SPC_GM",
"Factors":{"Genotype":"Control","Brain region":"SPC_GM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"393_SPC-GM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"518_SPC_GM",
"Factors":{"Genotype":"Control","Brain region":"SPC_GM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"518_SPC-GM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"613_SPC_GM",
"Factors":{"Genotype":"Control","Brain region":"SPC_GM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"613_SPC-GM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"662_SPC_GM",
"Factors":{"Genotype":"Control","Brain region":"SPC_GM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"662_SPC-GM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"688_SPC_GM",
"Factors":{"Genotype":"Control","Brain region":"SPC_GM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"688_SPC-GM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"758_SPC_GM",
"Factors":{"Genotype":"Control","Brain region":"SPC_GM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"758_SPC-GM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"831_SPC_GM",
"Factors":{"Genotype":"Control","Brain region":"SPC_GM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"831_SPC-GM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"851_SPC_GM",
"Factors":{"Genotype":"Control","Brain region":"SPC_GM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"851_SPC-GM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"925_SPC_GM",
"Factors":{"Genotype":"Control","Brain region":"SPC_GM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"925_SPC-GM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"436_SPC_GM",
"Factors":{"Genotype":"C9orf72","Brain region":"SPC_GM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"436_SPC-GM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"448_SPC_GM",
"Factors":{"Genotype":"C9orf72","Brain region":"SPC_GM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"448_SPC-GM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"526_SPC_GM",
"Factors":{"Genotype":"C9orf72","Brain region":"SPC_GM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"526_SPC-GM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"625_SPC_GM",
"Factors":{"Genotype":"C9orf72","Brain region":"SPC_GM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"625_SPC-GM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"729_SPC_GM",
"Factors":{"Genotype":"C9orf72","Brain region":"SPC_GM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"729_SPC-GM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"732_SPC_GM",
"Factors":{"Genotype":"C9orf72","Brain region":"SPC_GM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"732_SPC-GM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"736_SPC_GM",
"Factors":{"Genotype":"C9orf72","Brain region":"SPC_GM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"736_SPC-GM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"754_SPC_GM",
"Factors":{"Genotype":"C9orf72","Brain region":"SPC_GM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"754_SPC-GM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"785_SPC_GM",
"Factors":{"Genotype":"C9orf72","Brain region":"SPC_GM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"785_SPC-GM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"806_SPC_GM",
"Factors":{"Genotype":"C9orf72","Brain region":"SPC_GM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"806_SPC-GM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"918_SPC_GM",
"Factors":{"Genotype":"C9orf72","Brain region":"SPC_GM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"918_SPC-GM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"486_SPC_GM",
"Factors":{"Genotype":"GRN","Brain region":"SPC_GM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"486_SPC-GM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"531_SPC_GM",
"Factors":{"Genotype":"GRN","Brain region":"SPC_GM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"531_SPC-GM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"540_SPC_GM",
"Factors":{"Genotype":"GRN","Brain region":"SPC_GM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"540_SPC-GM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"677_SPC_GM",
"Factors":{"Genotype":"GRN","Brain region":"SPC_GM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"677_SPC-GM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"731_SPC_GM",
"Factors":{"Genotype":"GRN","Brain region":"SPC_GM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"731_SPC-GM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"738_SPC_GM",
"Factors":{"Genotype":"GRN","Brain region":"SPC_GM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"738_SPC-GM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"366_n_SPC_GM",
"Factors":{"Genotype":"Control","Brain region":"SPC_GM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"366_SPC-GM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"384_n_SPC_GM",
"Factors":{"Genotype":"Control","Brain region":"SPC_GM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"384_SPC-GM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"393_n_SPC_GM",
"Factors":{"Genotype":"Control","Brain region":"SPC_GM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"393_SPC-GM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"518_n_SPC_GM",
"Factors":{"Genotype":"Control","Brain region":"SPC_GM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"518_SPC-GM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"613_n_SPC_GM",
"Factors":{"Genotype":"Control","Brain region":"SPC_GM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"613_SPC-GM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"662_n_SPC_GM",
"Factors":{"Genotype":"Control","Brain region":"SPC_GM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"662_SPC-GM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"688_n_SPC_GM",
"Factors":{"Genotype":"Control","Brain region":"SPC_GM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"688_SPC-GM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"758_n_SPC_GM",
"Factors":{"Genotype":"Control","Brain region":"SPC_GM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"758_SPC-GM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"831_n_SPC_GM",
"Factors":{"Genotype":"Control","Brain region":"SPC_GM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"831_SPC-GM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"851_n_SPC_GM",
"Factors":{"Genotype":"Control","Brain region":"SPC_GM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"851_SPC-GM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"925_n_SPC_GM",
"Factors":{"Genotype":"Control","Brain region":"SPC_GM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"925_SPC-GM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"436_n_SPC_GM",
"Factors":{"Genotype":"C9orf72","Brain region":"SPC_GM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"436_SPC-GM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"448_n_SPC_GM",
"Factors":{"Genotype":"C9orf72","Brain region":"SPC_GM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"448_SPC-GM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"526_n_SPC_GM",
"Factors":{"Genotype":"C9orf72","Brain region":"SPC_GM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"526_SPC-GM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"625_n_SPC_GM",
"Factors":{"Genotype":"C9orf72","Brain region":"SPC_GM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"625_SPC-GM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"729_n_SPC_GM",
"Factors":{"Genotype":"C9orf72","Brain region":"SPC_GM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"729_SPC-GM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"732_n_SPC_GM",
"Factors":{"Genotype":"C9orf72","Brain region":"SPC_GM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"732_SPC-GM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"736_n_SPC_GM",
"Factors":{"Genotype":"C9orf72","Brain region":"SPC_GM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"736_SPC-GM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"754_n_SPC_GM",
"Factors":{"Genotype":"C9orf72","Brain region":"SPC_GM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"754_SPC-GM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"785_n_SPC_GM",
"Factors":{"Genotype":"C9orf72","Brain region":"SPC_GM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"785_SPC-GM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"806_n_SPC_GM",
"Factors":{"Genotype":"C9orf72","Brain region":"SPC_GM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"806_SPC-GM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"918_n_SPC_GM",
"Factors":{"Genotype":"C9orf72","Brain region":"SPC_GM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"918_SPC-GM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"486_n_SPC_GM",
"Factors":{"Genotype":"GRN","Brain region":"SPC_GM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"486_SPC-GM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"531_n_SPC_GM",
"Factors":{"Genotype":"GRN","Brain region":"SPC_GM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"531_SPC-GM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"540_n_SPC_GM",
"Factors":{"Genotype":"GRN","Brain region":"SPC_GM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"540_SPC-GM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"677_n_SPC_GM",
"Factors":{"Genotype":"GRN","Brain region":"SPC_GM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"677_SPC-GM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"731_n_SPC_GM",
"Factors":{"Genotype":"GRN","Brain region":"SPC_GM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"731_SPC-GM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"738_n_SPC_GM",
"Factors":{"Genotype":"GRN","Brain region":"SPC_GM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"738_SPC-GM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"366_SPC_WM",
"Factors":{"Genotype":"Control","Brain region":"SPC_WM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"366_SPC-WM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"384_SPC_WM",
"Factors":{"Genotype":"Control","Brain region":"SPC_WM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"384_SPC-WM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"393_SPC_WM",
"Factors":{"Genotype":"Control","Brain region":"SPC_WM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"393_SPC-WM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"518_SPC_WM",
"Factors":{"Genotype":"Control","Brain region":"SPC_WM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"518_SPC-WM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"613_SPC_WM",
"Factors":{"Genotype":"Control","Brain region":"SPC_WM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"613_SPC-WM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"662_SPC_WM",
"Factors":{"Genotype":"Control","Brain region":"SPC_WM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"662_SPC-WM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"688_SPC_WM",
"Factors":{"Genotype":"Control","Brain region":"SPC_WM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"688_SPC-WM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"758_SPC_WM",
"Factors":{"Genotype":"Control","Brain region":"SPC_WM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"758_SPC-WM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"831_SPC_WM",
"Factors":{"Genotype":"Control","Brain region":"SPC_WM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"831_SPC-WM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"851_SPC_WM",
"Factors":{"Genotype":"Control","Brain region":"SPC_WM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"851_SPC-WM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"925_SPC_WM",
"Factors":{"Genotype":"Control","Brain region":"SPC_WM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"925_SPC-WM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"436_SPC_WM",
"Factors":{"Genotype":"C9orf72","Brain region":"SPC_WM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"436_SPC-WM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"448_SPC_WM",
"Factors":{"Genotype":"C9orf72","Brain region":"SPC_WM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"448_SPC-WM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"526_SPC_WM",
"Factors":{"Genotype":"C9orf72","Brain region":"SPC_WM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"526_SPC-WM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"625_SPC_WM",
"Factors":{"Genotype":"C9orf72","Brain region":"SPC_WM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"625_SPC-WM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"729_SPC_WM",
"Factors":{"Genotype":"C9orf72","Brain region":"SPC_WM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"729_SPC-WM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"732_SPC_WM",
"Factors":{"Genotype":"C9orf72","Brain region":"SPC_WM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"732_SPC-WM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"736_SPC_WM",
"Factors":{"Genotype":"C9orf72","Brain region":"SPC_WM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"736_SPC-WM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"754_SPC_WM",
"Factors":{"Genotype":"C9orf72","Brain region":"SPC_WM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"754_SPC-WM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"785_SPC_WM",
"Factors":{"Genotype":"C9orf72","Brain region":"SPC_WM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"785_SPC-WM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"806_SPC_WM",
"Factors":{"Genotype":"C9orf72","Brain region":"SPC_WM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"806_SPC-WM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"918_SPC_WM",
"Factors":{"Genotype":"C9orf72","Brain region":"SPC_WM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"918_SPC-WM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"486_SPC_WM",
"Factors":{"Genotype":"GRN","Brain region":"SPC_WM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"486_SPC-WM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"531_SPC_WM",
"Factors":{"Genotype":"GRN","Brain region":"SPC_WM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"531_SPC-WM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"540_SPC_WM",
"Factors":{"Genotype":"GRN","Brain region":"SPC_WM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"540_SPC-WM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"677_SPC_WM",
"Factors":{"Genotype":"GRN","Brain region":"SPC_WM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"677_SPC-WM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"731_SPC_WM",
"Factors":{"Genotype":"GRN","Brain region":"SPC_WM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"731_SPC-WM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"738_SPC_WM",
"Factors":{"Genotype":"GRN","Brain region":"SPC_WM"},
"Additional sample data":{"MS Polarity":"Positive","RAW_FILE_NAME":"738_SPC-WM.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"366_n_SPC_WM",
"Factors":{"Genotype":"Control","Brain region":"SPC_WM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"366_SPC-WM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"384_n_SPC_WM",
"Factors":{"Genotype":"Control","Brain region":"SPC_WM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"384_SPC-WM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"393_n_SPC_WM",
"Factors":{"Genotype":"Control","Brain region":"SPC_WM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"393_SPC-WM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"518_n_SPC_WM",
"Factors":{"Genotype":"Control","Brain region":"SPC_WM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"518_SPC-WM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"613_n_SPC_WM",
"Factors":{"Genotype":"Control","Brain region":"SPC_WM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"613_SPC-WM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"662_n_SPC_WM",
"Factors":{"Genotype":"Control","Brain region":"SPC_WM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"662_SPC-WM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"688_n_SPC_WM",
"Factors":{"Genotype":"Control","Brain region":"SPC_WM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"688_SPC-WM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"758_n_SPC_WM",
"Factors":{"Genotype":"Control","Brain region":"SPC_WM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"758_SPC-WM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"831_n_SPC_WM",
"Factors":{"Genotype":"Control","Brain region":"SPC_WM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"831_SPC-WM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"851_n_SPC_WM",
"Factors":{"Genotype":"Control","Brain region":"SPC_WM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"851_SPC-WM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"925_n_SPC_WM",
"Factors":{"Genotype":"Control","Brain region":"SPC_WM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"925_SPC-WM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"436_n_SPC_WM",
"Factors":{"Genotype":"C9orf72","Brain region":"SPC_WM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"436_SPC-WM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"448_n_SPC_WM",
"Factors":{"Genotype":"C9orf72","Brain region":"SPC_WM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"448_SPC-WM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"526_n_SPC_WM",
"Factors":{"Genotype":"C9orf72","Brain region":"SPC_WM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"526_SPC-WM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"625_n_SPC_WM",
"Factors":{"Genotype":"C9orf72","Brain region":"SPC_WM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"625_SPC-WM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"729_n_SPC_WM",
"Factors":{"Genotype":"C9orf72","Brain region":"SPC_WM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"729_SPC-WM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"732_n_SPC_WM",
"Factors":{"Genotype":"C9orf72","Brain region":"SPC_WM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"732_SPC-WM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"736_n_SPC_WM",
"Factors":{"Genotype":"C9orf72","Brain region":"SPC_WM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"736_SPC-WM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"754_n_SPC_WM",
"Factors":{"Genotype":"C9orf72","Brain region":"SPC_WM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"754_SPC-WM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"785_n_SPC_WM",
"Factors":{"Genotype":"C9orf72","Brain region":"SPC_WM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"785_SPC-WM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"806_n_SPC_WM",
"Factors":{"Genotype":"C9orf72","Brain region":"SPC_WM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"806_SPC-WM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"918_n_SPC_WM",
"Factors":{"Genotype":"C9orf72","Brain region":"SPC_WM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"918_SPC-WM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"486_n_SPC_WM",
"Factors":{"Genotype":"GRN","Brain region":"SPC_WM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"486_SPC-WM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"531_n_SPC_WM",
"Factors":{"Genotype":"GRN","Brain region":"SPC_WM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"531_SPC-WM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"540_n_SPC_WM",
"Factors":{"Genotype":"GRN","Brain region":"SPC_WM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"540_SPC-WM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"677_n_SPC_WM",
"Factors":{"Genotype":"GRN","Brain region":"SPC_WM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"677_SPC-WM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"731_n_SPC_WM",
"Factors":{"Genotype":"GRN","Brain region":"SPC_WM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"731_SPC-WM_n.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"738_n_SPC_WM",
"Factors":{"Genotype":"GRN","Brain region":"SPC_WM"},
"Additional sample data":{"MS Polarity":"Negative","RAW_FILE_NAME":"738_SPC-WM_n.mzXML"}
}
],
"COLLECTION":{"COLLECTION_SUMMARY":"Frozen brain tissue was homogenised by bead beating at 4°C in ice cold HEPES buffer (50mM, pH 7.4) plus 5 mM NaF, 2 mM Na3VO4, 10 mM KCl and cOmplete Mini EDTA-free Protease Inhibitor Cocktail","SAMPLE_TYPE":"Brain","STORAGE_CONDITIONS":"-80℃"},

"TREATMENT":{"TREATMENT_SUMMARY":"Samples were obtained from frontotemporal dementia cases with inherited gene mutations in either GRN, or C9orf72 gene repeat expansion carriers and controls."},

"SAMPLEPREP":{"SAMPLEPREP_SUMMARY":"Lipids were extracted from 100uL of brain homogenate using a two-phase methyl-tert-butyl ether (MTBE)/methanol/water protocol as described by Matyash et al. (2008), with the addition of the following internal standards: 2000 pmoles SM(d18:1_12:0), 2000 pmoles GluCer(d18:1_12:0), 500 pmoles LacCer(d18:1_12:0), 500 pmoles ST(18:1_17:0), 500 pmoles Cer(18:1/17:0), 200 pmoles C17:0 Sph, 200 pmoles C17:1 S1P, 200 pmoles d3-C16 AcCa, 500 pmoles C17:1 LPE, 500 pmoles C17:1 LPS, 200 pmoles C17:0 LPA, 500 pmoles C17:0 LPC, 5000 pmoles PC(19:0_19:0), 2000 pmoles PS(17:0_17:0), 2000 pmoles C17:0 PE, 2000 pmoles C17:0 PG, 1000 pmoles C17:0 PA, 1000 pmoles d7-18:1_15:0 PI, 2000 pmoles CL(14:0_14:0_14:0_14:0), 2000 pmoles TAG(17:0_17:0_17:0), 500 pmoles DAG d7- 18:1/15:0), 500 pmoles d7- 18:1 MAG, 2000 pmoles C17:0 CholE, 1000 pmoles d7 Chol. Lipids were reconstituted in 400uL of 100% HPLC methanol, then diluted 1/5 in 80% v/v HPLC methanol, containing 1 mM ammonium formate and 0.2% formic acid."},

"CHROMATOGRAPHY":{"CHROMATOGRAPHY_TYPE":"Reversed phase","INSTRUMENT_NAME":"Thermo Vanquish","COLUMN_NAME":"Waters ACQUITY UPLC CSH C18 (100 x 2.1mm,1.7um)","SOLVENT_A":"60% acetonitrile/40% water; 0.1% formic acid; 10 mM ammonium formate","SOLVENT_B":"90% isopropanol/ 10% acetonitrile; 0.1% formic acid; 10 mM ammonium formate","FLOW_GRADIENT":"0 min, 80:20 A/B; 3 min, 80:20 A/B; 5.5 min, 55:45 A/B; 8 min, 36:65 A/B; 13 min, 15:85 A/B; 14 min, 0:100 A/B; 20 min, 0:100 A/B; 20.2 min, 70:30 A/B; 27 min, 70:30 A/B","FLOW_RATE":"0.28 mL/min","COLUMN_TEMPERATURE":"45"},

"ANALYSIS":{"ANALYSIS_TYPE":"MS"},

"MS":{"INSTRUMENT_NAME":"Thermo Q Exactive HF-X Orbitrap","INSTRUMENT_TYPE":"Orbitrap","MS_TYPE":"ESI","ION_MODE":"NEGATIVE","MS_COMMENTS":"MS data was acquired in full scan/data-dependent MS2 (full scan resolution 60,000 FWHM, scan range 220–1600 m/z) in both positive and negative ionization modes. The ten most abundant ions in each cycle were subjected to MS2, with an isolation window of 1.4 m/z, collision energy 30 eV, resolution 17,500 FWHM, maximum integration time 110 ms and dynamic exclusion window 10 s. An exclusion list of background ions was used based on a solvent blank. An inclusion list of the [M+H]+ and [M-H]- ions was used for all internal standards. LipidSearch software v4.2 (Thermo Fisher) was used for lipid annotation, chromatogram alignment, and peak integration from extracted ion chromatograms. Lipid annotation was based on precursor and product ions in both positive and negative ion mode. Individual lipids were expressed as ratios to an internal standard specific for each lipid class, then multiplied by the amount of internal standard added to produce a molar amount of each lipid per sample, which was normalised to protein amount in each sample."},

"MS_METABOLITE_DATA":{
"Units":"pmoles/mg protein",

"Data":[{"Metabolite":"PE(16:0_16:0)-H","925_n_SFG_GM":"319.121","851_n_SFG_GM":"340.293","831_n_SFG_GM":"896.490","758_n_SFG_GM":"301.220","688_n_SFG_GM":"745.985","662_n_SFG_GM":"672.367","613_n_SFG_GM":"547.618","518_n_SFG_GM":"177.080","393_n_SFG_GM":"478.063","384_n_SFG_GM":"677.632","366_n_SFG_GM":"263.435","918_n_SFG_GM":"396.601","806_n_SFG_GM":"738.642","785_n_SFG_GM":"252.632","754_n_SFG_GM":"417.073","736_n_SFG_GM":"512.044","732_n_SFG_GM":"867.651","729_n_SFG_GM":"200.050","625_n_SFG_GM":"358.832","526_n_SFG_GM":"752.938","448_n_SFG_GM":"353.490","436_n_SFG_GM":"842.359","738_n_SFG_GM":"707.260","731_n_SFG_GM":"366.762","677_n_SFG_GM":"939.052","540_n_SFG_GM":"400.047","531_n_SFG_GM":"437.381","486_n_SFG_GM":"447.690","925_n_SFG_WM":"380.402","851_n_SFG_WM":"407.065","831_n_SFG_WM":"2527.884","758_n_SFG_WM":"235.032","688_n_SFG_WM":"217.105","662_n_SFG_WM":"450.385","613_n_SFG_WM":"603.531","518_n_SFG_WM":"514.564","393_n_SFG_WM":"881.117","384_n_SFG_WM":"1154.140","366_n_SFG_WM":"517.315","918_n_SFG_WM":"632.323","806_n_SFG_WM":"282.652","785_n_SFG_WM":"392.056","754_n_SFG_WM":"512.482","736_n_SFG_WM":"756.217","732_n_SFG_WM":"210.255","729_n_SFG_WM":"954.047","625_n_SFG_WM":"1119.508","526_n_SFG_WM":"557.956","448_n_SFG_WM":"883.243","436_n_SFG_WM":"320.040","738_n_SFG_WM":"168.765","731_n_SFG_WM":"217.198","677_n_SFG_WM":"456.457","540_n_SFG_WM":"283.590","531_n_SFG_WM":"378.326","486_n_SFG_WM":"210.638","925_n_SPC_GM":"378.897","851_n_SPC_GM":"642.576","831_n_SPC_GM":"1007.174","758_n_SPC_GM":"356.623","688_n_SPC_GM":"450.569","662_n_SPC_GM":"447.338","613_n_SPC_GM":"442.757","518_n_SPC_GM":"358.964","393_n_SPC_GM":"365.210","384_n_SPC_GM":"397.542","366_n_SPC_GM":"247.544","918_n_SPC_GM":"399.948","806_n_SPC_GM":"414.853","785_n_SPC_GM":"554.757","754_n_SPC_GM":"334.495","736_n_SPC_GM":"328.444","732_n_SPC_GM":"408.064","729_n_SPC_GM":"290.232","625_n_SPC_GM":"321.027","526_n_SPC_GM":"314.921","448_n_SPC_GM":"285.313","436_n_SPC_GM":"360.043","738_n_SPC_GM":"481.655","731_n_SPC_GM":"344.219","677_n_SPC_GM":"425.215","540_n_SPC_GM":"410.651","531_n_SPC_GM":"502.285","486_n_SPC_GM":"275.805","925_n_SPC_WM":"401.733","851_n_SPC_WM":"558.981","831_n_SPC_WM":"445.067","758_n_SPC_WM":"440.415","688_n_SPC_WM":"668.793","662_n_SPC_WM":"381.028","613_n_SPC_WM":"1564.910","518_n_SPC_WM":"1136.188","393_n_SPC_WM":"1088.012","384_n_SPC_WM":"2254.667","366_n_SPC_WM":"381.694","918_n_SPC_WM":"773.654","806_n_SPC_WM":"325.226","785_n_SPC_WM":"1042.131","754_n_SPC_WM":"391.629","736_n_SPC_WM":"519.969","732_n_SPC_WM":"563.225","729_n_SPC_WM":"539.870","625_n_SPC_WM":"895.569","526_n_SPC_WM":"342.867","448_n_SPC_WM":"984.695","436_n_SPC_WM":"351.099","738_n_SPC_WM":"761.755","731_n_SPC_WM":"695.723","677_n_SPC_WM":"584.358","540_n_SPC_WM":"534.325","531_n_SPC_WM":"472.558","486_n_SPC_WM":"374.587"},{"Metabolite":"PE(34:0)-H","925_n_SFG_GM":"1343.486","851_n_SFG_GM":"1599.167","831_n_SFG_GM":"4511.342","758_n_SFG_GM":"2822.209","688_n_SFG_GM":"5565.429","662_n_SFG_GM":"2844.172","613_n_SFG_GM":"4755.208","518_n_SFG_GM":"1556.648","393_n_SFG_GM":"2311.409","384_n_SFG_GM":"2321.649","366_n_SFG_GM":"1553.394","918_n_SFG_GM":"1635.992","806_n_SFG_GM":"4764.708","785_n_SFG_GM":"1376.407","754_n_SFG_GM":"1885.026","736_n_SFG_GM":"2072.884","732_n_SFG_GM":"4518.663","729_n_SFG_GM":"1067.777","625_n_SFG_GM":"1278.538","526_n_SFG_GM":"3877.252","448_n_SFG_GM":"1618.756","436_n_SFG_GM":"3162.028","738_n_SFG_GM":"6281.013","731_n_SFG_GM":"1459.459","677_n_SFG_GM":"3981.059","540_n_SFG_GM":"1891.678","531_n_SFG_GM":"1710.688","486_n_SFG_GM":"4024.083","925_n_SFG_WM":"543.797","851_n_SFG_WM":"561.797","831_n_SFG_WM":"2358.289","758_n_SFG_WM":"421.225","688_n_SFG_WM":"418.721","662_n_SFG_WM":"630.295","613_n_SFG_WM":"944.781","518_n_SFG_WM":"775.330","393_n_SFG_WM":"1233.224","384_n_SFG_WM":"1211.353","366_n_SFG_WM":"881.120","918_n_SFG_WM":"937.137","806_n_SFG_WM":"455.011","785_n_SFG_WM":"752.941","754_n_SFG_WM":"722.833","736_n_SFG_WM":"811.705","732_n_SFG_WM":"439.728","729_n_SFG_WM":"1740.532","625_n_SFG_WM":"1425.054","526_n_SFG_WM":"1137.945","448_n_SFG_WM":"1284.946","436_n_SFG_WM":"702.333","738_n_SFG_WM":"405.072","731_n_SFG_WM":"467.436","677_n_SFG_WM":"570.035","540_n_SFG_WM":"482.693","531_n_SFG_WM":"1122.535","486_n_SFG_WM":"373.587","925_n_SPC_GM":"2215.506","851_n_SPC_GM":"4465.732","831_n_SPC_GM":"7765.452","758_n_SPC_GM":"3361.367","688_n_SPC_GM":"3135.421","662_n_SPC_GM":"3080.613","613_n_SPC_GM":"3711.996","518_n_SPC_GM":"3178.494","393_n_SPC_GM":"1948.051","384_n_SPC_GM":"2021.251","366_n_SPC_GM":"1902.026","918_n_SPC_GM":"2635.043","806_n_SPC_GM":"3457.131","785_n_SPC_GM":"5388.621","754_n_SPC_GM":"1838.725","736_n_SPC_GM":"1894.488","732_n_SPC_GM":"2659.458","729_n_SPC_GM":"2841.455","625_n_SPC_GM":"2023.172","526_n_SPC_GM":"1665.345","448_n_SPC_GM":"1870.433","436_n_SPC_GM":"2416.853","738_n_SPC_GM":"3334.421","731_n_SPC_GM":"2387.492","677_n_SPC_GM":"2291.203","540_n_SPC_GM":"3760.207","531_n_SPC_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}

}