{
"METABOLOMICS WORKBENCH":{"STUDY_ID":"ST002505","ANALYSIS_ID":"AN004126","VERSION":"1","CREATED_ON":"March 20, 2023, 7:16 am"},

"PROJECT":{"PROJECT_TITLE":"A Mammalian Conserved Circular RNA CircLARP2 Regulates Hepatocellular Carcinoma Metastasis and Lipid Metabolism","PROJECT_SUMMARY":"Circular RNAs (circRNAs) have emerged as crucial regulators in physiology and human diseases. However, evolutionarily conserved circRNAs with potent functions in cancers are rarely reported. Here, we identified a mammalian conserved circRNA circLARP2 that played critical roles in hepatocellular carcinoma (HCC). With clinical specimens, we found that patients with high circLARP2 levels in HCC had advanced prognostic stage and poor overall survival. CircLARP2 facilitated HCC metastasis and lipid accumulation in HCC cell lines. CircLARP2 was one of the rare ones that were identified in HCC metastasis and conserved in mammals, which enabled further studies with animal models. CircLARP2-deficient mice exhibited reduced metastasis and less lipid accumulation in an induced HCC model. We provided lines of evidence at molecular, cellular, and whole organismal levels, to support that circLARP2 functioned as a protein sponge of AUF1. CircLARP2 sequestered AUF1 from binding to LKB1 mRNA, which led to decreased LKB1 mRNA stability and lower LKB1 protein levels. LKB1 as a kinase promoted the phosphorylation of AMPK and then the phosphorylation of ACC, the rate limiting enzyme of fatty acid synthesis. Knockdown of Lkb1 with AAV8-shLkb1 in mice HCC model also proved that Lkb1 was a key element in the regulation. Through this AUF1-LKB1-AMPK-ACC pathway, circLARP2 promoted HCC metastasis and lipid accumulation.","INSTITUTE":"University of Science and Technology of China","LAST_NAME":"Li","FIRST_NAME":"Jingxin","ADDRESS":"443 Huangshan Road","EMAIL":"ljx0418@mail.ustc.edu.cn","PHONE":"00-86-0551-63600137"},

"STUDY":{"STUDY_TITLE":"A Mammalian Conserved Circular RNA CircLARP2 Regulates Hepatocellular Carcinoma Metastasis and Lipid Metabolism (Part 1)","STUDY_SUMMARY":"Circular RNAs (circRNAs) have emerged as crucial regulators in physiology and human diseases. However, evolutionarily conserved circRNAs with potent functions in cancers are rarely reported. Here, we identified a mammalian conserved circRNA circLARP2 that played critical roles in hepatocellular carcinoma (HCC). With clinical specimens, we found that patients with high circLARP2 levels in HCC had advanced prognostic stage and poor overall survival. CircLARP2 facilitated HCC metastasis and lipid accumulation in HCC cell lines. CircLARP2 was one of the rare ones that were identified in HCC metastasis and conserved in mammals, which enabled further studies with animal models. CircLARP2-deficient mice exhibited reduced metastasis and less lipid accumulation in an induced HCC model. We provided lines of evidence at molecular, cellular, and whole organismal levels, to support that circLARP2 functioned as a protein sponge of AUF1. CircLARP2 sequestered AUF1 from binding to LKB1 mRNA, which led to decreased LKB1 mRNA stability and lower LKB1 protein levels. LKB1 as a kinase promoted the phosphorylation of AMPK and then the phosphorylation of ACC, the rate limiting enzyme of fatty acid synthesis. Knockdown of Lkb1 with AAV8-shLkb1 in mice HCC model also proved that Lkb1 was a key element in the regulation. Through this AUF1-LKB1-AMPK-ACC pathway, circLARP2 promoted HCC metastasis and lipid accumulation.","INSTITUTE":"University of Science and Technology of China","LAST_NAME":"Li","FIRST_NAME":"Jingxin","ADDRESS":"443 Huangshan Road","EMAIL":"ljx0418@mail.ustc.edu.cn","PHONE":"00-86-0551-63600137"},

"SUBJECT":{"SUBJECT_TYPE":"Cultured cells","SUBJECT_SPECIES":"Homo sapiens","TAXONOMY_ID":"9606"},
"SUBJECT_SAMPLE_FACTORS":[
{
"Subject ID":"-",
"Sample ID":"PLC-WT-1_POS",
"Factors":{"Genotype":"Wild-type"},
"Additional sample data":{"RAW_FILE_NAME":"PLC-WT-1_POS-PLC-WT-1.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"PLC-WT-2_POS",
"Factors":{"Genotype":"Wild-type"},
"Additional sample data":{"RAW_FILE_NAME":"PLC-WT-2_POS-PLC-WT-2.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"PLC-WT-3_POS",
"Factors":{"Genotype":"Wild-type"},
"Additional sample data":{"RAW_FILE_NAME":"PLC-WT-3_POS-PLC-WT-3.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"PLC-WT-4_POS",
"Factors":{"Genotype":"Wild-type"},
"Additional sample data":{"RAW_FILE_NAME":"PLC-WT-4_POS-PLC-WT-4.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"PLC-WT-5_POS",
"Factors":{"Genotype":"Wild-type"},
"Additional sample data":{"RAW_FILE_NAME":"PLC-WT-5_POS-PLC-WT-5.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"PLC-WT-1_NEG",
"Factors":{"Genotype":"Wild-type"},
"Additional sample data":{"RAW_FILE_NAME":"PLC-WT-1_NEG-PLC-WT-1.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"PLC-WT-2_NEG",
"Factors":{"Genotype":"Wild-type"},
"Additional sample data":{"RAW_FILE_NAME":"PLC-WT-2_NEG-PLC-WT-2.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"PLC-WT-3_NEG",
"Factors":{"Genotype":"Wild-type"},
"Additional sample data":{"RAW_FILE_NAME":"PLC-WT-3_NEG-PLC-WT-3.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"PLC-WT-4_NEG",
"Factors":{"Genotype":"Wild-type"},
"Additional sample data":{"RAW_FILE_NAME":"PLC-WT-4_NEG-PLC-WT-4.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"PLC-WT-5_NEG",
"Factors":{"Genotype":"Wild-type"},
"Additional sample data":{"RAW_FILE_NAME":"PLC-WT-5_NEG-PLC-WT-5.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"L-WT-1_POS",
"Factors":{"Genotype":"Wild-type"},
"Additional sample data":{"RAW_FILE_NAME":"L-WT-1_POS.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"L-WT-2_POS",
"Factors":{"Genotype":"Wild-type"},
"Additional sample data":{"RAW_FILE_NAME":"L-WT-2_POS.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"L-WT-3_POS",
"Factors":{"Genotype":"Wild-type"},
"Additional sample data":{"RAW_FILE_NAME":"L-WT-3_POS.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"L-WT-4_POS",
"Factors":{"Genotype":"Wild-type"},
"Additional sample data":{"RAW_FILE_NAME":"L-WT-4_POS.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"L-WT-5_POS",
"Factors":{"Genotype":"Wild-type"},
"Additional sample data":{"RAW_FILE_NAME":"L-WT-5_POS.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"L-WT-1_NEG",
"Factors":{"Genotype":"Wild-type"},
"Additional sample data":{"RAW_FILE_NAME":"L-WT-1_NEG.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"L-WT-2_NEG",
"Factors":{"Genotype":"Wild-type"},
"Additional sample data":{"RAW_FILE_NAME":"L-WT-2_NEG.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"L-WT-3_NEG",
"Factors":{"Genotype":"Wild-type"},
"Additional sample data":{"RAW_FILE_NAME":"L-WT-3_NEG.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"L-WT-4_NEG",
"Factors":{"Genotype":"Wild-type"},
"Additional sample data":{"RAW_FILE_NAME":"L-WT-4_NEG.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"L-WT-5_NEG",
"Factors":{"Genotype":"Wild-type"},
"Additional sample data":{"RAW_FILE_NAME":"L-WT-5_NEG.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"PLC-KO-1_NEG",
"Factors":{"Genotype":"circLARP2-deficient"},
"Additional sample data":{"RAW_FILE_NAME":"PLC-KO-1_NEG-PLC-KO-1.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"PLC-KO-2_NEG",
"Factors":{"Genotype":"circLARP2-deficient"},
"Additional sample data":{"RAW_FILE_NAME":"PLC-KO-2_NEG-PLC-KO-2.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"PLC-KO-3_NEG",
"Factors":{"Genotype":"circLARP2-deficient"},
"Additional sample data":{"RAW_FILE_NAME":"PLC-KO-3_NEG-PLC-KO-3.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"PLC-KO-4_NEG",
"Factors":{"Genotype":"circLARP2-deficient"},
"Additional sample data":{"RAW_FILE_NAME":"PLC-KO-4_NEG-PLC-KO-4.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"PLC-KO-5_NEG",
"Factors":{"Genotype":"circLARP2-deficient"},
"Additional sample data":{"RAW_FILE_NAME":"PLC-KO-5_NEG-PLC-KO-5.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"PLC-KO-1_POS",
"Factors":{"Genotype":"circLARP2-deficient"},
"Additional sample data":{"RAW_FILE_NAME":"PLC-KO-1_POS-PLC-KO-1.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"PLC-KO-2_POS",
"Factors":{"Genotype":"circLARP2-deficient"},
"Additional sample data":{"RAW_FILE_NAME":"PLC-KO-2_POS-PLC-KO-2.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"PLC-KO-3_POS",
"Factors":{"Genotype":"circLARP2-deficient"},
"Additional sample data":{"RAW_FILE_NAME":"PLC-KO-3_POS-PLC-KO-3.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"PLC-KO-4_POS",
"Factors":{"Genotype":"circLARP2-deficient"},
"Additional sample data":{"RAW_FILE_NAME":"PLC-KO-4_POS-PLC-KO-4.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"PLC-KO-5_POS",
"Factors":{"Genotype":"circLARP2-deficient"},
"Additional sample data":{"RAW_FILE_NAME":"PLC-KO-5_POS-PLC-KO-5.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"L-KO-1_POS",
"Factors":{"Genotype":"circLARP2-deficient"},
"Additional sample data":{"RAW_FILE_NAME":"L-KO-1_POS.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"L-KO-2_POS",
"Factors":{"Genotype":"circLARP2-deficient"},
"Additional sample data":{"RAW_FILE_NAME":"L-KO-2_POS.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"L-KO-3_POS",
"Factors":{"Genotype":"circLARP2-deficient"},
"Additional sample data":{"RAW_FILE_NAME":"L-KO-3_POS.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"L-KO-4_POS",
"Factors":{"Genotype":"circLARP2-deficient"},
"Additional sample data":{"RAW_FILE_NAME":"L-KO-4_POS.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"L-KO-5_POS",
"Factors":{"Genotype":"circLARP2-deficient"},
"Additional sample data":{"RAW_FILE_NAME":"L-KO-5_POS.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"L-KO-1_NEG",
"Factors":{"Genotype":"circLARP2-deficient"},
"Additional sample data":{"RAW_FILE_NAME":"L-KO-1_NEG.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"L-KO-2_NEG",
"Factors":{"Genotype":"circLARP2-deficient"},
"Additional sample data":{"RAW_FILE_NAME":"L-KO-2_NEG.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"L-KO-3_NEG",
"Factors":{"Genotype":"circLARP2-deficient"},
"Additional sample data":{"RAW_FILE_NAME":"L-KO-3_NEG.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"L-KO-4_NEG",
"Factors":{"Genotype":"circLARP2-deficient"},
"Additional sample data":{"RAW_FILE_NAME":"L-KO-4_NEG.mzXML"}
},
{
"Subject ID":"-",
"Sample ID":"L-KO-5_NEG",
"Factors":{"Genotype":"circLARP2-deficient"},
"Additional sample data":{"RAW_FILE_NAME":"L-KO-5_NEG.mzXML"}
}
],
"COLLECTION":{"COLLECTION_SUMMARY":"Cells were counted, washed with cold PBS abd then flash-frozen in liquid N2","SAMPLE_TYPE":"Cultured cells"},

"TREATMENT":{"TREATMENT_SUMMARY":"Wild-type and circLARP2-deficient PLC cells with no Special treatment"},

"SAMPLEPREP":{"SAMPLEPREP_SUMMARY":"The cells were washed with PBS under 37°C and the PBS was removed. 800 μL of cold methanol/acetonitrile (1:1, v/v) to remove the protein and extract the metabolites. The mixture was collected into a new centrifuge tube, and centrifuged at 14000g for 20 min to collect the supernatant. The supernatant was dried in a vacuum centri fuge. For LC MS analysis, the samples were redissolved in 100 μL acetonitrile/water (1:1, v/v) solvent and centrifuged at 14000 g at 4 ℃ for 15 min, then the supernatant was injected."},

"CHROMATOGRAPHY":{"CHROMATOGRAPHY_TYPE":"HILIC","INSTRUMENT_NAME":"Agilent 1290 Infinity","COLUMN_NAME":"Waters ACQUITY UPLC BEH Amide (100 x 2.1mm,1.7um)","SOLVENT_A":"100% water; 25 mM ammonium acetate; 25 mM ammonium hydroxide","SOLVENT_B":"100% acetonitrile","FLOW_GRADIENT":"The gradient was 95% B for 0.5 min and was linearly reduced to 65% in 6.5 min, and then was reduced to 40% in 1 min and kept for 1 min, and then increased to 95% in 0.1 min, with a 3 min","FLOW_RATE":"0.5 mL/min","COLUMN_TEMPERATURE":"25℃"},

"ANALYSIS":{"ANALYSIS_TYPE":"MS"},

"MS":{"INSTRUMENT_NAME":"ABI Sciex 6600 TripleTOF","INSTRUMENT_TYPE":"Triple TOF","MS_TYPE":"ESI","ION_MODE":"POSITIVE","MS_COMMENTS":"The mobile phase contained A=25 mM ammonium acetate and 25 mM ammonium hydroxide in water and B= acetonitrile. The gr adient was 95% B for 0.5 min and was linearly reduced to 65% in 6.5 min, and then was reduced to 40% in 1 min and kept for 1 min, and then increased to 95% in 0.1 min, with a 3 min reequilibration period employed.","MS_RESULTS_FILE":"ST002505_AN004126_Results.txt UNITS:peak area Has m/z:No Has RT:No RT units:No RT data"},

"MS_METABOLITE_DATA":{
"Units":"Peak area",

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G(16:1e_17:1_18:1)+NH4"},{"metabolite_name":"TG(16:1e_14:0_16:1)+NH4"},{"metabolite_name":"TG(16:1e_14:0_16:0)+NH4"},{"metabolite_name":"TG(16:1e_10:4_19:1)+H"},{"metabolite_name":"TG(16:1_20:1_22:2)+NH4"},{"metabolite_name":"TG(16:1_18:2_22:6)+NH4"},{"metabolite_name":"TG(16:1_18:1_22:6)+NH4"},{"metabolite_name":"TG(16:1_18:1_20:3)+H"},{"metabolite_name":"TG(16:1_18:1_18:3)+NH4"},{"metabolite_name":"TG(16:1_18:1_18:2)+NH4"},{"metabolite_name":"TG(16:1_18:1_18:1)+NH4"},{"metabolite_name":"TG(16:1_17:1_18:2)+NH4"},{"metabolite_name":"TG(16:1_17:1_18:1)+NH4"},{"metabolite_name":"TG(16:1_16:1_22:6)+NH4"},{"metabolite_name":"TG(16:1_16:1_22:0)+NH4"},{"metabolite_name":"TG(16:1_16:1_18:2)+NH4"},{"metabolite_name":"TG(16:1_16:1_18:1)+NH4"},{"metabolite_name":"TG(16:1_16:1_17:1)+NH4"},{"metabolite_name":"TG(16:1_14:1_18:1)+NH4"},{"metabolite_name":"TG(16:1_14:1_17:1)+NH4"},{"metabolite_name":"TG(16:1_14:0_22:6)+NH4"},{"metabolite_name":"TG(16:1_14:0_20:4)+NH4"},{"metabolite_name":"TG(16:1_14:0_18:1)+NH4"},{"metabolite_name":"TG(16:1_13:0_18:1)+NH4"},{"metabolite_name":"TG(16:1_12:0_18:1)+NH4"},{"metabolite_name":"TG(16:1_12:0_17:1)+NH4"},{"metabolite_name":"TG(16:1_11:2_22:6)+H"},{"metabolite_name":"TG(16:0e_22:6_22:6)+NH4"},{"metabolite_name":"TG(16:0e_22:5_22:6)+NH4"},{"metabolite_name":"TG(16:0e_19:1_22:6)+NH4"},{"metabolite_name":"TG(16:0e_18:1_22:5)+NH4"},{"metabolite_name":"TG(16:0e_18:1_22:4)+NH4"},{"metabolite_name":"TG(16:0e_17:1_22:6)+NH4"},{"metabolite_name":"TG(16:0e_17:1_18:1)+NH4"},{"metabolite_name":"TG(16:0e_16:1_22:6)+NH4"},{"metabolite_name":"TG(16:0e_16:1_18:1)+NH4"},{"metabolite_name":"TG(16:0e_16:1_17:1)+NH4"},{"metabolite_name":"TG(16:0e_16:0_22:6)+H"},{"metabolite_name":"TG(16:0e_16:0_22:4)+H"},{"metabolite_name":"TG(16:0e_16:0_18:1)+NH4"},{"metabolite_name":"TG(16:0e_16:0_17:1)+NH4"},{"metabolite_name":"TG(16:0e_15:0_16:0)+NH4"},{"metabolite_name":"TG(16:0e_14:0_22:6)+NH4"},{"metabolite_name":"TG(16:0e_14:0_16:0)+NH4"},{"metabolite_name":"TG(16:0e_11:0_12:0)+NH4"},{"metabolite_name":"TG(16:0_9:0_18:1)+NH4"},{"metabolite_name":"TG(16:0_6:0_18:1)+NH4"},{"metabolite_name":"TG(16:0_22:6_24:1)+NH4"},{"metabolite_name":"TG(16:0_22:6_22:6)+NH4"},{"metabolite_name":"TG(16:0_22:5_22:6)+NH4"},{"metabolite_name":"TG(16:0_20:4_22:6)+NH4"},{"metabolite_name":"TG(16:0_20:4_20:4)+H"},{"metabolite_name":"TG(16:0_18:3_22:6)+H"},{"metabolite_name":"TG(16:0_18:1_24:0)+NH4"},{"metabolite_name":"TG(16:0_18:1_22:6)+NH4"},{"metabolite_name":"TG(16:0_18:1_22:5)+NH4"},{"metabolite_name":"TG(16:0_18:1_20:1)+NH4"},{"metabolite_name":"TG(16:0_18:1_19:0)+NH4"},{"metabolite_name":"TG(16:0_18:1_18:1)+NH4"},{"metabolite_name":"TG(16:0_17:1_22:6)+NH4"},{"metabolite_name":"TG(16:0_17:1_18:1)+NH4"},{"metabolite_name":"TG(16:0_17:0_22:6)+NH4"},{"metabolite_name":"TG(16:0_17:0_18:1)+NH4"},{"metabolite_name":"TG(16:0_16:1_22:6)+NH4"},{"metabolite_name":"TG(16:0_16:1_22:6)+H"},{"metabolite_name":"TG(16:0_16:1_22:5)+NH4"},{"metabolite_name":"TG(16:0_16:1_18:1)+NH4"},{"metabolite_name":"TG(16:0_16:0_18:1)+NH4"},{"metabolite_name":"TG(16:0_16:0_18:1)+Na"},{"metabolite_name":"TG(16:0_16:0_17:0)+NH4"},{"metabolite_name":"TG(16:0_16:0_16:0)+NH4"},{"metabolite_name":"TG(16:0_16:0_16:0)+Na"},{"metabolite_name":"TG(16:0_14:1_16:1)+NH4"},{"metabolite_name":"TG(16:0_14:0_22:6)+NH4"},{"metabolite_name":"TG(16:0_14:0_18:1)+NH4"},{"metabolite_name":"TG(16:0_14:0_17:1)+Na"},{"metabolite_name":"TG(16:0_14:0_16:1)+NH4"},{"metabolite_name":"TG(16:0_14:0_16:0)+NH4"},{"metabolite_name":"TG(16:0_14:0_14:0)+NH4"},{"metabolite_name":"TG(16:0_13:0_16:1)+NH4"},{"metabolite_name":"TG(16:0_13:0_14:0)+NH4"},{"metabolite_name":"TG(16:0_12:0_22:6)+NH4"},{"metabolite_name":"TG(16:0_12:0_18:1)+NH4"},{"metabolite_name":"TG(16:0_12:0_12:0)+NH4"},{"metabolite_name":"TG(16:0_10:3_11:1)+NH4"},{"metabolite_name":"TG(16:0_10:2_10:4)+NH4"},{"metabolite_name":"TG(16:0_10:0_18:2)+NH4"},{"metabolite_name":"TG(16:0_10:0_18:1)+NH4"},{"metabolite_name":"TG(16:0_10:0_12:0)+NH4"},{"metabolite_name":"TG(15:0_20:3_22:6)+NH4"},{"metabolite_name":"TG(15:0_16:1_18:1)+NH4"},{"metabolite_name":"TG(15:0_16:1_16:1)+NH4"},{"metabolite_name":"TG(15:0_16:0_22:6)+NH4"},{"metabolite_name":"TG(15:0_16:0_22:4)+H"},{"metabolite_name":"TG(15:0_16:0_20:5)+NH4"},{"metabolite_name":"TG(15:0_16:0_18:1)+NH4"},{"metabolite_name":"TG(15:0_16:0_16:0)+NH4"},{"metabolite_name":"TG(15:0_16:0_16:0)+Na"},{"metabolite_name":"TG(15:0_14:0_18:1)+NH4"},{"metabolite_name":"TG(15:0_14:0_16:1)+NH4"},{"metabolite_name":"TG(15:0_14:0_16:0)+NH4"},{"metabolite_name":"TG(14:1e_22:5_22:5)+H"},{"metabolite_name":"TG(14:1e_20:0_22:6)+H"},{"metabolite_name":"TG(14:1e_20:0_20:4)+H"},{"metabolite_name":"TG(14:1e_17:1_22:5)+Na"},{"metabolite_name":"TG(14:1_10:4_10:4)+Na"},{"metabolite_name":"TG(14:1_10:1_12:2)+NH4"},{"metabolite_name":"TG(14:0e_6:0_15:0)+H"},{"metabolite_name":"TG(14:0e_14:0_16:0)+NH4"},{"metabolite_name":"TG(13:0_12:3_12:3)+NH4"},{"metabolite_name":"TG(12:1e_6:0_22:6)+H"},{"metabolite_name":"TG(12:1e_6:0_20:3)+H"},{"metabolite_name":"TG(12:1e_6:0_18:1)+H"},{"metabolite_name":"TG(12:1e_22:5_22:6)+H"},{"metabolite_name":"TG(12:1e_22:5_22:5)+H"},{"metabolite_name":"TG(12:1e_20:5_22:5)+H"},{"metabolite_name":"TG(12:1e_20:3_22:3)+Na"},{"metabolite_name":"TG(12:1e_18:1_18:1)+NH4"},{"metabolite_name":"TG(12:1e_16:1_21:1)+NH4"},{"metabolite_name":"TG(12:0e_8:0_22:5)+NH4"},{"metabolite_name":"TG(12:0e_8:0_12:0)+Na"},{"metabolite_name":"TG(12:0e_6:0_22:6)+H"},{"metabolite_name":"TG(12:0e_6:0_20:4)+H"},{"metabolite_name":"TG(12:0e_22:5_22:5)+H"},{"metabolite_name":"TG(12:0e_22:3_22:5)+Na"},{"metabolite_name":"TG(12:0e_20:5_20:5)+H"},{"metabolite_name":"TG(12:0e_20:3_22:6)+Na"},{"metabolite_name":"TG(12:0e_20:3_22:5)+Na"},{"metabolite_name":"TG(12:0e_18:2_22:5)+Na"},{"metabolite_name":"TG(12:0e_18:2_20:5)+Na"},{"metabolite_name":"TG(12:0e_18:1_22:1)+Na"},{"metabolite_name":"TG(12:0e_16:0_22:1)+Na"},{"metabolite_name":"TG(12:0_14:0_18:2)+NH4"},{"metabolite_name":"TG(12:0_14:0_14:0)+NH4"},{"metabolite_name":"TG(12:0_12:0_18:2)+NH4"},{"metabolite_name":"TG(12:0_12:0_14:0)+NH4"},{"metabolite_name":"TG(12:0_12:0_12:0)+NH4"},{"metabolite_name":"TG(11:0_10:3_10:4)+NH4"},{"metabolite_name":"TG(10:0_18:2_18:2)+NH4"},{"metabolite_name":"TG(10:0_18:1_18:2)+NH4"},{"metabolite_name":"TG(10:0_12:0_18:1)+NH4"},{"metabolite_name":"TG(10:0_12:0_14:0)+NH4"},{"metabolite_name":"TG(10:0_11:2_11:2)+H"},{"metabolite_name":"Tetrandrine"},{"metabolite_name":"Tetramethrin"},{"metabolite_name":"Tetrahydrofolate"},{"metabolite_name":"Tetrahydrocurcumin"},{"metabolite_name":"Tetraethylene 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acid"},{"metabolite_name":"Hc toxin"},{"metabolite_name":"Harringtonine"},{"metabolite_name":"Harmaline"},{"metabolite_name":"Halofantrine"},{"metabolite_name":"Guanosine diphosphate"},{"metabolite_name":"Guanosine 5'-monophosphate"},{"metabolite_name":"Guanosine 5'-diphospho-.alpha.-d-mannose"},{"metabolite_name":"Guanosine 5'-diphosphate (GDP)"},{"metabolite_name":"Guanine"},{"metabolite_name":"Guanidoacetic acid"},{"metabolite_name":"Guanidine"},{"metabolite_name":"Gramine"},{"metabolite_name":"Gomisin 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.beta.-d-glucuronide"},{"metabolite_name":"4-ketopimelic acid"},{"metabolite_name":"4-imidazoleacrylic acid"},{"metabolite_name":"4-hydroxy-l-isoleucine"},{"metabolite_name":"4-hydroxydebrisoquine"},{"metabolite_name":"4-hydroxy-3-methoxyphenethyl alcohol"},{"metabolite_name":"4-hydroxy-1-(2-hydroxyethyl)-2,2,6,6-tetramethylpiperidine"},{"metabolite_name":"4-Hexen-1-ol, (E)-"},{"metabolite_name":"4h-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine-4-acetamide, 6-(4-chlorophenyl)-n-ethyl-8-methoxy-1-methyl-, (4s)-"},{"metabolite_name":"4-fluoroamphetamine"},{"metabolite_name":"4-fluoro-.alpha.-pyrrolidinobutiophenone"},{"metabolite_name":"4-deoxypyridoxine"},{"metabolite_name":"4'-benzyloxycarvedilol"},{"metabolite_name":"4-androsten-17.beta.-ol-3-one glucosiduronate"},{"metabolite_name":"4-Aminobutyric acid(GABA)"},{"metabolite_name":"4-acetoxy-n,n-diisopropyltryptamine"},{"metabolite_name":"4-acetamidobutanoate"},{"metabolite_name":"4,4-dimethyl-l-glutamic acid"},{"metabolite_name":"4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone"},{"metabolite_name":"4-(methylamino)-4-(3-pyridyl)butyric acid"},{"metabolite_name":"4-(1-piperazinyl)-1h-indole"},{"metabolite_name":"3-ureidopropionic acid"},{"metabolite_name":"3'-sialyllactose"},{"metabolite_name":"3'-o-methylguanosine"},{"metabolite_name":"3'-O-methyladenosine"},{"metabolite_name":"3-methyl-2-buten-1-ol"},{"metabolite_name":"3-methoxyprostaglandin f1.alpha."},{"metabolite_name":"3-hydroxypyridine"},{"metabolite_name":"3-Hydroxykynurenine"},{"metabolite_name":"3-hydroxyisovaleric acid"},{"metabolite_name":"3-hydroxyhexadecanoylcarnitine"},{"metabolite_name":"3-hydroxyanthranilic acid"},{"metabolite_name":"3-epilupeol"},{"metabolite_name":"3-deacetylsalannin"},{"metabolite_name":"3-aminoquinoline"},{"metabolite_name":"3-amino-2-(4-chlorophenyl)-2-hydroxypropanesulfonic acid"},{"metabolite_name":"3-alahpda [dmed-fahfa]"},{"metabolite_name":"3-acetoxypyridine"},{"metabolite_name":"3-[1-[3-(dimethylamino)propyl]-5-methoxy-1h-indol-3-yl]-4-(1h-indol-3-yl)-1h-pyrrole-2,5-dione"},{"metabolite_name":"3,6,9,12-tetraoxatetracosan-1-ol"},{"metabolite_name":"3',5'-cyclic damp"},{"metabolite_name":"3,5,9-trioxa-4-phosphatetracosan-1-aminium, 7-(acetyloxy)-24-carboxy-4-hydroxy-n,n,n-trimethyl-, inner salt, 4-oxide, (r)-"},{"metabolite_name":"3-(2-Hydroxyethyl)indole"},{"metabolite_name":"3-(1h-indol-3-ylmethyl)-6,18-dimethyl-12-(1-phenylethyl)-9,15-di(propan-2-yl)-1,4,7,10,13,16,19-heptazacyclotricosane-2,5,8,11,14,17,20-heptone"},{"metabolite_name":"2-sdahpda [dmed-fahfa]"},{"metabolite_name":"2-sdahma [dmed-fahfa]"},{"metabolite_name":"2-pivaloyl-1,3-indandione"},{"metabolite_name":"2-piperidinecarboxylic acid, 1-(3,3-dimethyl-1,2-dioxopentyl)-, (1r)-1-(3-aminophenyl)-3-(3,4-dimethoxyphenyl)propyl ester, (2s)-"},{"metabolite_name":"2-palmitoyl-rac-glycerol"},{"metabolite_name":"2-oxiraneacetic acid, 3-phenyl-, cyano(6-methoxy-2-naphthalenyl)methyl ester"},{"metabolite_name":"2-o-rhamnosylvitexin"},{"metabolite_name":"2'-o-methylcytidine"},{"metabolite_name":"2'-o-methyladenosine"},{"metabolite_name":"2-oleoyl-1-stearoyl-sn-glycero-3-phosphoserine"},{"metabolite_name":"2-oleoyl-1-palmitoyl-sn-glycero-3-phosphocholine"},{"metabolite_name":"2-methylindole"},{"metabolite_name":"2-methylbutyryl-l-carnitine"},{"metabolite_name":"2-methylamino-1-phenylbutane"},{"metabolite_name":"2-Methoxybenzoic acid"},{"metabolite_name":"2-hydroxyphenethyl alcohol"},{"metabolite_name":"2-hydroxybenzyl alcohol"},{"metabolite_name":"2-Hydroxyadenine"},{"metabolite_name":"2-hydroxyacetophenone"},{"metabolite_name":"2-hydroxy-4-methylbenzoic acid"},{"metabolite_name":"2-hexadecanoylthio-1-ethylphosphorylcholine"},{"metabolite_name":"2'-fucosyllactose"},{"metabolite_name":"2-epahpda [dmed-fahfa]"},{"metabolite_name":"2-epahpa [dmed-fahfa]"},{"metabolite_name":"2-docosahexaenoyl-1-stearoyl-sn-glycero-3-phosphoserine"},{"metabolite_name":"2-dhahma [dmed-fahfa]"},{"metabolite_name":"2-butylaniline"},{"metabolite_name":"2-butenamide, n-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3s)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-"},{"metabolite_name":"2-benzothiazolsulfonic acid"},{"metabolite_name":"2-arachidonoylglycerol"},{"metabolite_name":"2-Amino-2-methyl-1,3-propanediol"},{"metabolite_name":"2-amino-1-phenylethanol"},{"metabolite_name":"2-alahhda [dmed-fahfa]"},{"metabolite_name":"2-acetamido-2-deoxy-3-o-(.beta.-d-galactopyranosyl)-d-glucopyranose"},{"metabolite_name":"21-deacetoxy-11-oxodeflazacort-3,20-hydrazinecarboxamide"},{"metabolite_name":"2-[[7-hydroxy-1-(4-hydroxy-3,5-dimethoxyphenyl)-3-(hydroxymethyl)-6,8-dimethoxy-1,2,3,4-tetrahydronaphthalen-2-yl]methoxy]oxane-3,4,5-triol"},{"metabolite_name":"2,6-di-tert-butyl-4-hydroxymethylphenol"},{"metabolite_name":"2,4-thiazolidinedione, 3-(2-aminoethyl)-5-[(4-ethoxyphenyl)methylene]-"},{"metabolite_name":"2',4'-Dihydroxyacetophenone"},{"metabolite_name":"2,4,6-tri-tert-butylaniline"},{"metabolite_name":"2,3-dinor-8-isoprostaglandin-f2.alpha."},{"metabolite_name":"2',3'-dideoxyadenosine"},{"metabolite_name":"2,3,9,10,11,12-hexahydro-10s-hydroxy-9-methyl-1-oxo-9r,12s-epoxy-1h-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid, hexyl ester"},{"metabolite_name":"2,2-bis[hydroxymethyl]-2,2',2''-nitrilotriethanol"},{"metabolite_name":"2,2,6,6-tetramethyl-4 piperidone"},{"metabolite_name":"2-(n-morpholino)ethanesulfonic acid"},{"metabolite_name":"2-(n-ethyl-n-m-toluidino)ethanol"},{"metabolite_name":"2-(5-oxovaleryl)phosphatidylcholine"},{"metabolite_name":"2(1H)-Pyridinone"},{"metabolite_name":"1-Stearoyl-sn-glycerol 3-phosphocholine"},{"metabolite_name":"1-stearoyl-rac-glycerol"},{"metabolite_name":"1-Stearoyl-2-oleoyl-sn-glycerol 3-phosphocholine (SOPC)"},{"metabolite_name":"1-stearoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine"},{"metabolite_name":"1-stearoyl-2-hydroxy-sn-glycero-3-phosphocholine"},{"metabolite_name":"1-stearoyl-2-docosahexaenoyl-sn-glycerol"},{"metabolite_name":"1-stearoyl-2-docosahexaenoyl-sn-glycero-3-phosphocholine"},{"metabolite_name":"1-stearoyl-2-arachidonoyl-sn-glycero-3-phospho-(1'-myo-inositol)"},{"metabolite_name":"1-pentadecanoyl-sn-glycero-3-phosphocholine"},{"metabolite_name":"1-palmitoyl-sn-glycero-3-phosphocholine"},{"metabolite_name":"1-Palmitoyllysophosphatidylcholine"},{"metabolite_name":"1-Palmitoylglycerol"},{"metabolite_name":"1-palmitoyl-2-stearoyl-sn-glycero-3-phosphocholine"},{"metabolite_name":"1-palmitoyl-2-oleoyl-sn-glycerol"},{"metabolite_name":"1-palmitoyl-2-oleoyl-3-linoleoyl-rac-glycerol"},{"metabolite_name":"1-palmitoyl-2-myristoyl-sn-glycero-3-phosphocholine"},{"metabolite_name":"1-palmitoyl-2-lauroyl-sn-glycero-3-phosphorylcholine"},{"metabolite_name":"1-palmitoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine"},{"metabolite_name":"1-palmitoyl-2-glutaryl phosphatidylcholine"},{"metabolite_name":"1-palmitoyl-2-docosahexaenoyl-sn-glycero-3-phosphocholine"},{"metabolite_name":"1-palmitoyl-2-azelaoylphosphatidylcholine"},{"metabolite_name":"1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphoserine"},{"metabolite_name":"1-o-octadecyl-sn-glyceryl-3-phosphorylcholine"},{"metabolite_name":"1-oleoyl-sn-glycero-3-phosphoethanolamine"},{"metabolite_name":"1-oleoyl-sn-glycero-3-phosphocholine"},{"metabolite_name":"1-oleoyl-2-myristoyl-sn-glycero-3-phosphocholine"},{"metabolite_name":"1-o-hexadecyl-2-o-(2e-butenoyl)-sn-glyceryl-3-phosphocholine"},{"metabolite_name":"1-o-hexadecyl-2-deoxy-2-thio-s-acetyl-sn-glyceryl-3-phosphorylcholine"},{"metabolite_name":"1-octadecyl-2-acetyl-sn-glycero-3-phosphocholine"},{"metabolite_name":"1-myristoyl-sn-glycero-3-phosphocholine"},{"metabolite_name":"1-methyl-l-histidine"},{"metabolite_name":"1-methylhistidine"},{"metabolite_name":"1-methyladenosine"},{"metabolite_name":"1h-indole-5-sulfonamide, n-(3-chlorophenyl)-3-[[3,5-dimethyl-4-[(4-methyl-1-piperazinyl)carbonyl]-1h-pyrrol-2-yl]methylene]-2,3-dihydro-n-methyl-2-oxo-, (3z)-"},{"metabolite_name":"1h-indole-1-pentanoic acid, 3-[2-(2-chlorophenyl)acetyl]-"},{"metabolite_name":"1h-indazole-4-carboxamide, n-[(1,2-dihydro-6-methyl-2-oxo-4-propyl-3-pyridinyl)methyl]-1-(1-methylethyl)-6-[2-(4-methyl-1-piperazinyl)-4-pyridinyl]-"},{"metabolite_name":"1h-indazole-4-carboxamide, n- [(1,2-dihydro-6-methyl-2-oxo-4-propyl-3-pyridinyl)methyl]- 1-(1-methylethyl)-6-[6-[4-(1-methylethyl)-1-piperazinyl]-3- pyridinyl]-"},{"metabolite_name":"1-hexadecyl-sn-glycero-3-phosphocholine"},{"metabolite_name":"1-hexadecylamine"},{"metabolite_name":"1-hexadecyl-2-azelaoyl-sn-glycero-3-phosphocholine"},{"metabolite_name":"1-hexadecyl-2-(9z-octadecenoyl)-sn-glycero-3-phosphocholine"},{"metabolite_name":"1-hexadecyl-2-(8z,11z,14z-eicosatrienoyl)-sn-glycero-3-phosphocholine"},{"metabolite_name":"1-hexadecyl-2-(5z,8z,11z,14z-eicosatetraenoyl)-sn-glycero-3-phosphocholine"},{"metabolite_name":"1-hexadecanoyl-2-sn-glycero-3-phosphate"},{"metabolite_name":"1-hexadecanoyl-2-octadecadienoyl-sn-glycero-3-phosphocholine"},{"metabolite_name":"1-heptadecanoyl-sn-glycero-3-phosphocholine"},{"metabolite_name":"1-ethyl-4-(4-piperidinyl)piperazine"},{"metabolite_name":"1-Eicosatrienoyl-sn-glycero-3-phosphoethanolamine"},{"metabolite_name":"1-decanoyl-2-hydroxy-sn-glycero-3-phosphocholine"},{"metabolite_name":"1-Aminocyclopropanecarboxylic acid"},{"metabolite_name":"19-noretiocholanolone glucuronide"},{"metabolite_name":"17-trifluoromethylphenyltrinorprostaglandin f2.alpha. methyl ester"},{"metabolite_name":"17-trifluoromethylphenyltrinorprostaglandin f2.alpha. isopropyl ester"},{"metabolite_name":"17alpha-ethynylestradiol"},{"metabolite_name":"16-oxocafestol"},{"metabolite_name":"15-deoxy-goyazensolide"},{"metabolite_name":"15(s)-15-methylprostaglandin f2.alpha. ethylamide"},{"metabolite_name":"15(s)-15-methylprostaglandin e1"},{"metabolite_name":"10-formyl-7,8-dihydrofolic acid"},{"metabolite_name":"10-deacetylbaccatin iii"},{"metabolite_name":"1-[1-(1-methylcyclooctyl)-4-piperidinyl]-2-[(3r)-3-piperidinyl]-1h-benzimidazole"},{"metabolite_name":"1-[(4-chlorophenyl)methyl]-3-[(1,1-dimethylethyl)thio]-.alpha.,.alpha.- dimethyl-5-(1-methylethyl)-1h-indole-2-propanoic acid"},{"metabolite_name":"1,3-propanediol, 2-amino-2-[2-[4-[[6-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]hexyl]oxy]phenyl]ethyl]-"},{"metabolite_name":"1,3-diphenylguanidine"},{"metabolite_name":"1,3,4,6-tetra-o-acetyl-.beta.-d-mannopyranose"},{"metabolite_name":"1,2-dithiolane-3-pentanamide, n,n'-1,3-propanediylbis-"},{"metabolite_name":"1,2-ditetradecanoyl-sn-glycero-3-phosphocholine"},{"metabolite_name":"1,2-dipentadecanoyl-sn-glycero-3-phosphocholine"},{"metabolite_name":"1,2-dipalmitoleoyl-sn-glycero-3-phosphocholine"},{"metabolite_name":"1,2-dioleoyl-sn-glycerol"},{"metabolite_name":"1,2-dioleoyl-sn-glycero-3-phospho-(1'-myo-inositol)"},{"metabolite_name":"1,2-dioleoyl-sn-glycero-3-phosphatidylcholine"},{"metabolite_name":"1,2-dimyristoyl-sn-glycero-3-phosphate"},{"metabolite_name":"1,2-dilinoleoylglycerol"},{"metabolite_name":"1,2-diamino-2-methylpropane"},{"metabolite_name":"1,2-bis(heptanoylthio) glycerophosphocholine"},{"metabolite_name":"1,2,3-Benzenetriol"},{"metabolite_name":"1-(4-piperidinyl)-1,3-dihydro-2h-indol-2-one"},{"metabolite_name":"1-(3-chlorophenyl)piperazine"},{"metabolite_name":"1-(2-pyridinyl)-4-piperidinylamine"},{"metabolite_name":"1-(1z-octadecenyl)-sn-glycero-3-phosphocholine"},{"metabolite_name":"1-(1z-octadecenyl)-2-(5z,8z,11z,14z-eicosatetraenoyl)-sn-glycero-3-phosphocholine"},{"metabolite_name":"1-(1z-octadecenyl)-2-(4z,7z,10z,13z,16z,19z-docosahexaenoyl)-sn-glycero-3-phosphocholine"},{"metabolite_name":"1-(1z-hexadecenyl)-sn-glycero-3-phosphocholine"},{"metabolite_name":"[5-acetyloxy-3-(hydroxymethyl)-2-oxo-6-propan-2-ylcyclohex-3-en-1-yl] 3-methylpentanoate"},{"metabolite_name":".tau.-fluvalinate"},{"metabolite_name":".gamma.-l-glu-.epsilon.-l-lys"},{"metabolite_name":".gamma.-aminobutyric acid"},{"metabolite_name":".beta.-nicotinamide adenine dinucleotide, reduced(NADH)"},{"metabolite_name":".beta.-nicotinamide adenine dinucleotide phosphate"},{"metabolite_name":".beta.-homoproline"},{"metabolite_name":".beta.-estradiol 17-valerate"},{"metabolite_name":".beta.-chloro-d-alanine"},{"metabolite_name":".beta.-carboline-1-propionic acid"},{"metabolite_name":".alpha.-tocopherol nicotinate"},{"metabolite_name":".alpha.-methyltryptamine"},{"metabolite_name":".alpha.-L-Glu-L-Tyr"},{"metabolite_name":".alpha.-L-Glu-L-Asp"},{"metabolite_name":".alpha.-L-Glu-Gly"},{"metabolite_name":".alpha.-guanidinoglutaric acid"},{"metabolite_name":".alpha.-cyperone"},{"metabolite_name":"(r)-(+)-arachidonyl-1'-hydroxy-2'-propylamide"},{"metabolite_name":"(4ar,5r,6as,6br,10s,12ar)-10-[(2r,3r,4r,5s,6r)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-5-hydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid"},{"metabolite_name":"(3s)-vestitol"},{"metabolite_name":"(3r,5r,6r,7s,9s,10r,13r,17r)-17-((r)-5-methoxy-5-oxopentan-2-yl)-10,13-dimethylhexadecahydro-1h-cyclopenta[a]phenanthrene-3,6,7-triyl triacetate"},{"metabolite_name":"(2s,3s)-3,5,7-trihydroxy-6-methyl-2-(3,4,5-trihydroxyphenyl)-2,3-dihydrochromen-4-one"},{"metabolite_name":"(2s,3r,4s,5s,6r)-2-[(2r,3r,4s,5s,6r)-2-[[(3s,6s,8r,10r,12r,13r,14r,17s)-3,12-dihydroxy-4,4,8,10,14-pentamethyl-17-[(2s)-6-methyl-2-[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhept-5-en-2-yl]-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1h-cyclopenta[a]phenanthren-6-yl]oxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol"},{"metabolite_name":"(2r,3s,4s,5r,6r)-6-[1,7-bis(4-hydroxyphenyl)heptan-3-yloxy]-5-[(2s,3r,4r)-3,4-dihydroxy-4-(hydroxymethyl)oxolan-2-yl]oxy-2-(hydroxymethyl)oxane-3,4-diol"},{"metabolite_name":"(2r,3s,4s,5r,6r)-5-[(2s,3r,4r)-3,4-dihydroxy-4-(hydroxymethyl)oxolan-2-yl]oxy-2-(hydroxymethyl)-6-(2-phenylethoxy)oxane-3,4-diol"},{"metabolite_name":"(2r,3s,4s,5r,6r)-2-[[(2s,3r,4r)-3,4-dihydroxy-4-(hydroxymethyl)oxolan-2-yl]oxymethyl]-6-[4-(4-hydroxyphenyl)butan-2-yloxy]oxane-3,4,5-triol"},{"metabolite_name":"(2e,4e)-hexa-2,4-dienoic acid"},{"metabolite_name":"(+)-costunolide"},{"metabolite_name":"(+-)8,9-DHET"},{"metabolite_name":"(.+/-.)-ethylphenidate"},{"metabolite_name":"(.+/-.)-dropropizine"},{"metabolite_name":"(-)-norepinephrine"},{"metabolite_name":"(-)-corey lactone diol"}]
}

}