#METABOLOMICS WORKBENCH araskind_20150605_9622801_mwtab.txt DATATRACK_ID:273 STUDY_ID:ST000176 ANALYSIS_ID:AN000271 PROJECT_ID:PR000148 VERSION 1 CREATED_ON 01-15-2019 #PROJECT PR:PROJECT_TITLE trcp PR:PROJECT_SUMMARY metabolic phenotypes of a clock mutant mouse PR:INSTITUTE Florida State University PR:DEPARTMENT Biomedical Sciences PR:LABORATORY Lee Lab PR:LAST_NAME Lee PR:FIRST_NAME Choogon PR:ADDRESS Tallahassee, FL PR:EMAIL choogon.lee@med.fsu.edu PR:PHONE 850-645-1478 PR:DOI http://dx.doi.org/10.21228/M8V011 #STUDY ST:STUDY_TITLE cell and liver metabolomics ST:STUDY_SUMMARY (Pending) Liver samples were harvested from wt and ko mice. Quadruplicates and ST:STUDY_SUMMARY triplicates are sent for cells and liver, respectively. ST:INSTITUTE University of Michigan ST:DEPARTMENT Biomedical Research Core Facilities ST:LABORATORY Metabolomics core ST:LAST_NAME Kachman ST:FIRST_NAME Maureen ST:ADDRESS 6300 Brehm Tower, 1000 Wall Street, Ann Arbor, MI 48105-5714 ST:EMAIL mkachman@umich.edu ST:PHONE - #SUBJECT SU:SUBJECT_TYPE Animal SU:SUBJECT_SPECIES Mus musculus SU:TAXONOMY_ID 10090 SU:SPECIES_GROUP Mammal #SUBJECT_SAMPLE_FACTORS: SUBJECT(optional)[tab]SAMPLE[tab]FACTORS(NAME:VALUE pairs separated by |)[tab]Additional sample data SUBJECT_SAMPLE_FACTORS SU0004026 S00014600 genotype:background | Type:liver SUBJECT_SAMPLE_FACTORS SU0004027 S00014601 genotype:background | Type:liver SUBJECT_SAMPLE_FACTORS SU0004028 S00014602 genotype:background | Type:liver SUBJECT_SAMPLE_FACTORS SU0004032 S00014606 genotype:background | Type:MFE Cells SUBJECT_SAMPLE_FACTORS SU0004033 S00014607 genotype:background | Type:MFE Cells SUBJECT_SAMPLE_FACTORS SU0004034 S00014608 genotype:background | Type:MFE Cells SUBJECT_SAMPLE_FACTORS SU0004035 S00014609 genotype:background | Type:MFE Cells SUBJECT_SAMPLE_FACTORS SU0004029 S00014603 genotype:knock-out | Type:liver SUBJECT_SAMPLE_FACTORS SU0004030 S00014604 genotype:knock-out | Type:liver SUBJECT_SAMPLE_FACTORS SU0004031 S00014605 genotype:knock-out | Type:liver SUBJECT_SAMPLE_FACTORS SU0004036 S00014610 genotype:knock-out | Type:MFE Cells SUBJECT_SAMPLE_FACTORS SU0004037 S00014611 genotype:knock-out | Type:MFE Cells SUBJECT_SAMPLE_FACTORS SU0004038 S00014612 genotype:knock-out | Type:MFE Cells SUBJECT_SAMPLE_FACTORS SU0004039 S00014613 genotype:knock-out | Type:MFE Cells #COLLECTION CO:SAMPLE_TYPE Cells CO:COLLECTION_SUMMARY - #TREATMENT TR:TREATMENT_SUMMARY - #SAMPLEPREP SP:SAMPLEPREP_PROTOCOL_FILENAME Gly-TCA-nucleotides_analysis_protocol-2015-03-09.docx SP:SAMPLEPREP_SUMMARY - #CHROMATOGRAPHY CH:METHODS_ID AQM011 CH:METHODS_FILENAME ALPHA_KETO_ACIDS-FULL.M.zip CH:INSTRUMENT_NAME Agilent 7890A CH:COLUMN_NAME Agilent DB5-MS (30m × 0.25mm, 0.25um) CH:CHROMATOGRAPHY_TYPE GC #ANALYSIS AN:LABORATORY_NAME MRC2 (University of Michigan) AN:ANALYSIS_TYPE MS AN:ACQUISITION_PARAMETERS_FILE ALPHA_KETO_ACIDS-FULL.M.zip #MS MS:MS_COMMENTS - MS:INSTRUMENT_NAME Agilent 5975C MS:INSTRUMENT_TYPE Single quadrupole MS:MS_TYPE EI MS:ION_MODE POSITIVE #MS_METABOLITE_DATA MS_METABOLITE_DATA:UNITS SUC MS_METABOLITE_DATA_START Samples S00014600 S00014600 S00014600 S00014600 S00014600 S00014600 S00014600 S00014600 S00014600 S00014600 S00014600 S00014600 S00014600 S00014600 S00014600 S00014600 S00014600 S00014601 S00014601 S00014601 S00014601 S00014601 S00014601 S00014601 S00014601 S00014601 S00014601 S00014601 S00014601 S00014601 S00014601 S00014601 S00014601 S00014601 S00014602 S00014602 S00014602 S00014602 S00014602 S00014602 S00014602 S00014602 S00014602 S00014602 S00014602 S00014602 S00014602 S00014602 S00014602 S00014602 S00014602 S00014606 S00014606 S00014606 S00014606 S00014606 S00014606 S00014606 S00014606 S00014606 S00014606 S00014606 S00014606 S00014606 S00014606 S00014606 S00014606 S00014606 S00014607 S00014607 S00014607 S00014607 S00014607 S00014607 S00014607 S00014607 S00014607 S00014607 S00014607 S00014607 S00014607 S00014607 S00014607 S00014607 S00014607 S00014608 S00014608 S00014608 S00014608 S00014608 S00014608 S00014608 S00014608 S00014608 S00014608 S00014608 S00014608 S00014608 S00014608 S00014608 S00014608 S00014608 S00014609 S00014609 S00014609 S00014609 S00014609 S00014609 S00014609 S00014609 S00014609 S00014609 S00014609 S00014609 S00014609 S00014609 S00014609 S00014609 S00014609 S00014603 S00014603 S00014603 S00014603 S00014603 S00014603 S00014603 S00014603 S00014603 S00014603 S00014603 S00014603 S00014603 S00014603 S00014603 S00014603 S00014603 S00014604 S00014604 S00014604 S00014604 S00014604 S00014604 S00014604 S00014604 S00014604 S00014604 S00014604 S00014604 S00014604 S00014604 S00014604 S00014604 S00014604 S00014605 S00014605 S00014605 S00014605 S00014605 S00014605 S00014605 S00014605 S00014605 S00014605 S00014605 S00014605 S00014605 S00014605 S00014605 S00014605 S00014605 S00014610 S00014610 S00014610 S00014610 S00014610 S00014610 S00014610 S00014610 S00014610 S00014610 S00014610 S00014610 S00014610 S00014610 S00014610 S00014610 S00014610 S00014611 S00014611 S00014611 S00014611 S00014611 S00014611 S00014611 S00014611 S00014611 S00014611 S00014611 S00014611 S00014611 S00014611 S00014611 S00014611 S00014611 S00014612 S00014612 S00014612 S00014612 S00014612 S00014612 S00014612 S00014612 S00014612 S00014612 S00014612 S00014612 S00014612 S00014612 S00014612 S00014612 S00014612 S00014613 S00014613 S00014613 S00014613 S00014613 S00014613 S00014613 S00014613 S00014613 S00014613 S00014613 S00014613 S00014613 S00014613 S00014613 S00014613 S00014613 Factors genotype:background | Type:liver genotype:background | Type:liver genotype:background | Type:liver genotype:background | Type:liver genotype:background | Type:liver genotype:background | Type:liver genotype:background | Type:liver genotype:background | Type:liver genotype:background | Type:liver genotype:background | Type:liver genotype:background | Type:liver genotype:background | Type:liver genotype:background | Type:liver genotype:background | Type:liver genotype:background | Type:liver genotype:background | Type:liver genotype:background | Type:liver genotype:background | Type:liver genotype:background | Type:liver genotype:background | Type:liver genotype:background | Type:liver genotype:background | Type:liver genotype:background | Type:liver genotype:background | Type:liver genotype:background | Type:liver genotype:background | Type:liver genotype:background | Type:liver genotype:background | Type:liver genotype:background | Type:liver genotype:background | Type:liver genotype:background | Type:liver genotype:background | Type:liver genotype:background | Type:liver genotype:background | Type:liver genotype:background | Type:liver genotype:background | Type:liver genotype:background | Type:liver genotype:background | Type:liver genotype:background | Type:liver genotype:background | Type:liver genotype:background | Type:liver genotype:background | Type:liver genotype:background | Type:liver genotype:background | Type:liver genotype:background | Type:liver genotype:background | Type:liver genotype:background | Type:liver genotype:background | Type:liver genotype:background | Type:liver genotype:background | Type:liver genotype:background | Type:liver genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:background | Type:MFE Cells genotype:knock-out | Type:liver genotype:knock-out | Type:liver genotype:knock-out | Type:liver genotype:knock-out | Type:liver genotype:knock-out | Type:liver genotype:knock-out | Type:liver genotype:knock-out | Type:liver genotype:knock-out | Type:liver genotype:knock-out | Type:liver genotype:knock-out | Type:liver genotype:knock-out | Type:liver genotype:knock-out | Type:liver genotype:knock-out | Type:liver genotype:knock-out | Type:liver genotype:knock-out | Type:liver genotype:knock-out | Type:liver genotype:knock-out | Type:liver genotype:knock-out | Type:liver genotype:knock-out | Type:liver genotype:knock-out | Type:liver genotype:knock-out | Type:liver genotype:knock-out | Type:liver genotype:knock-out | Type:liver genotype:knock-out | Type:liver genotype:knock-out | Type:liver genotype:knock-out | Type:liver genotype:knock-out | Type:liver genotype:knock-out | Type:liver genotype:knock-out | Type:liver genotype:knock-out | Type:liver genotype:knock-out | Type:liver genotype:knock-out | Type:liver genotype:knock-out | Type:liver genotype:knock-out | Type:liver genotype:knock-out | Type:liver genotype:knock-out | Type:liver genotype:knock-out | Type:liver genotype:knock-out | Type:liver genotype:knock-out | Type:liver genotype:knock-out | Type:liver genotype:knock-out | Type:liver genotype:knock-out | Type:liver genotype:knock-out | Type:liver genotype:knock-out | Type:liver genotype:knock-out | Type:liver genotype:knock-out | Type:liver genotype:knock-out | Type:liver genotype:knock-out | Type:liver genotype:knock-out | Type:liver genotype:knock-out | Type:liver genotype:knock-out | Type:liver genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells genotype:knock-out | Type:MFE Cells 2 or 3-phosphoglycerate 3.3750 2.6886 2.7026 1.1310 0.6546 0.7770 0.7355 4.2241 8.4486 4.8191 0.3566 0.3448 0.3581 0.3026 6-phosphogluconate 9.9619 9.1336 10.2890 0.7291 0.6231 0.3099 0.8556 14.4604 9.7777 17.4474 0.3878 0.3200 0.4853 0.2620 acetyl-coa 2.2952 1.1871 1.1749 0.0166 0.0234 0.0137 0.0172 0.5009 0.6267 0.7051 0.0048 0.0125 0.0064 0.0143 adenosine diphosphate 38.7268 34.9319 48.1097 6.5977 5.6402 4.6327 5.2377 32.4959 31.6910 34.7153 3.7995 3.7206 4.0165 3.1347 adenosine monophosphate 15335.9372 16088.4845 15339.4135 98.3611 59.2677 63.6334 65.0032 1682.3848 1209.6122 1665.7820 48.3663 48.1497 44.7888 39.0306 adenosine triphosphate 5.5533 4.4062 5.1210 7.5004 7.9436 4.5756 5.6072 5.3737 8.4641 6.0155 4.6461 5.1516 5.4112 4.0068 citrate or isocitrate 140.6182 345.6941 391.7658 10.5141 7.5351 8.2411 8.1638 381.5142 289.5899 588.3109 14.7735 13.7934 13.9790 13.0762 flavin adenine dinucleotide 76.7413 80.3526 92.5883 0.0751 0.0496 0.0520 0.0573 60.8838 44.6274 78.6284 0.0428 0.0405 0.0470 0.0461 fructose 1_6-bisphosphate 12.4260 8.5629 9.5887 32.2164 32.1044 20.6863 23.7126 13.5303 5.9714 5.1211 12.3090 12.5809 10.2809 9.2757 glucose 6-phosphate or fructose-6-phosphate 950.8926 919.9624 223.0251 33.5144 21.5649 23.9312 24.1882 471.0498 279.6316 522.0208 19.2890 19.9573 19.1622 18.0711 malate 928.8443 1140.6890 1069.3088 13.1866 11.2499 11.5625 11.8185 1119.7997 1044.1767 878.3906 7.9177 7.6852 8.1585 8.1721 nicotinamide adenine dinucleotide oxidized 24.7310 23.0387 28.1770 0.5546 0.6750 0.6038 0.6361 16.8331 13.5813 19.1031 0.4183 0.4297 0.4453 0.4823 nicotinamide adenine dinucleotide phosphate oxidized 5.3919 3.4386 6.7161 0.7299 0.6937 0.6547 0.6557 2.9527 4.1969 4.2237 0.3737 0.4499 0.3922 0.4602 nicotinamide adenine dinucleotide phosphate reduced 10.2042 2.0339 7.6384 1.2268 0.0511 0.0695 0.7407 5.1551 7.5003 0.1350 0.0601 nicotinamide adenine dinucleotide reduced 26.1559 16.7157 33.3147 0.0170 0.0057 0.0082 0.0107 16.1374 11.6041 21.2892 0.0072 0.0056 phosphoenolpyruvate 0.5493 1.7805 1.9719 6.8948 2.5286 0.0509 sucrose 1062.3703 1529.9088 1548.6423 7.6333 3.8523 4.1837 4.6011 222.2145 386.7444 281.0897 4.9525 5.2745 4.3699 3.4048 MS_METABOLITE_DATA_END #METABOLITES METABOLITES_START metabolite_name pubchem_id inchi_key kegg_id other_id other_id_type ri ri_type moverz_quant 2 or 3-phosphoglycerate 724 C00597 2PG/3PG UFLORIDA_Lee_Lab 6-phosphogluconate 91493 C00345 6PG UFLORIDA_Lee_Lab acetyl-coa 444493 C00024 aCoA UFLORIDA_Lee_Lab adenosine diphosphate 6022 C00008 ADP UFLORIDA_Lee_Lab adenosine monophosphate 6083 C00020 AMP UFLORIDA_Lee_Lab adenosine triphosphate 5957 C00002 ATP UFLORIDA_Lee_Lab citrate or isocitrate 311 C00158 CIT/ICIT UFLORIDA_Lee_Lab flavin adenine dinucleotide 643975 C00016 FAD UFLORIDA_Lee_Lab fructose 1,6-bisphosphate 172313 C00354 FBP UFLORIDA_Lee_Lab glucose 6-phosphate or fructose-6-phosphate 5958 C00092 G6P/F6P UFLORIDA_Lee_Lab malate 222656 C00149 MAL UFLORIDA_Lee_Lab nicotinamide adenine dinucleotide oxidized 10897651 C00003 NAD UFLORIDA_Lee_Lab nicotinamide adenine dinucleotide phosphate oxidized 5886 C00006 NADP UFLORIDA_Lee_Lab nicotinamide adenine dinucleotide phosphate reduced 5886 C00006 NADPH UFLORIDA_Lee_Lab nicotinamide adenine dinucleotide reduced 439153 C00004 NADH UFLORIDA_Lee_Lab phosphoenolpyruvate 1005 C00074 PEP UFLORIDA_Lee_Lab sucrose 5988 C00089 SUC UFLORIDA_Lee_Lab METABOLITES_END #END