#METABOLOMICS WORKBENCH hormel101_20170623_112854 DATATRACK_ID:1084 STUDY_ID:ST000635 ANALYSIS_ID:AN000967 PROJECT_ID:PR000457
VERSION             	1
CREATED_ON             	June 25, 2017, 9:17 am
#PROJECT
PR:PROJECT_TITLE                 	Metabolomic Mechanisms of Dietary Salt Effects on Blood Pressure
PR:PROJECT_SUMMARY               	Enhanced sensitivity of blood pressure to salt intake is observed in
PR:PROJECT_SUMMARY               	approximately 50% of hypertensive patients, reaching 75% in African American
PR:PROJECT_SUMMARY               	hypertensive patients. We recently discovered a novel role of abnormal cellular
PR:PROJECT_SUMMARY               	intermediary metabolism in hypertension in the Dahl salt-sensitive (SS) rat, the
PR:PROJECT_SUMMARY               	most commonly used polygenic, hereditary model of human salt-sensitive
PR:PROJECT_SUMMARY               	hypertension. We propose to test the hypothesis that blood pressure sensitivity
PR:PROJECT_SUMMARY               	to dietary salt intake in human is associated with metabolite changes in the
PR:PROJECT_SUMMARY               	urine. Leveraging the expertise and resources at the Mayo Clinic Metabolomics
PR:PROJECT_SUMMARY               	Resources Core, we propose to perform targeted LC/MS analysis and NMR spectra
PR:PROJECT_SUMMARY               	generation in urine samples obtained from a subset of subjects from the Dietary
PR:PROJECT_SUMMARY               	Approaches to Stop Hypertension – Sodium (DASH2) clinical trial and kidney
PR:PROJECT_SUMMARY               	tissue extract and urine samples from SS rats and a newly generated transgenic
PR:PROJECT_SUMMARY               	rat that overexpresses fumarase (SS.Fh1+). The study will be the first to
PR:PROJECT_SUMMARY               	systematically characterize urinary metabolite profiles associated with blood
PR:PROJECT_SUMMARY               	pressure response to salt in humans. The study is anticipated to generate new
PR:PROJECT_SUMMARY               	insight into the mechanisms (particularly renal mechanisms) underlying
PR:PROJECT_SUMMARY               	salt-sensitive hypertension. Findings of the proposed study could lead to an
PR:PROJECT_SUMMARY               	expanded clinical study as well as mechanistic studies in animal models.
PR:INSTITUTE                     	Mayo Clinic
PR:LAST_NAME                     	Liang
PR:FIRST_NAME                    	Mingyu
PR:ADDRESS                       	Medical College of Wisconsin 8701 Watertown Plank Road Milwaukee, WI 53226
PR:EMAIL                         	mliang@mcw.edu
PR:PHONE                         	414-955-8539
#STUDY
ST:STUDY_TITLE                   	Amino Acid Metabolites of Dietary Salt Effects on Blood Pressure in Human Urine
ST:STUDY_TITLE                   	from DASH2 Clinical Trial (part VIII)
ST:STUDY_SUMMARY                 	The objective of the study is to identify changes of urinary metabolite profiles
ST:STUDY_SUMMARY                 	associated with different responses to blood pressure to salt. Subjects are
ST:STUDY_SUMMARY                 	derived from The Dietary approaches to stop hypertension (DASH) diet, Sodium
ST:STUDY_SUMMARY                 	Intake and Blood Pressure Trial (Sacks FM et al PMID: 11136953,N Engl J Med.
ST:STUDY_SUMMARY                 	2001).We choose two groups subjects who meet the following conditions(the two
ST:STUDY_SUMMARY                 	groups are separately named A and B). We chose subjects on the Control diet
ST:STUDY_SUMMARY                 	.These subjects meet the blood pressure criteria described below:Group A
ST:STUDY_SUMMARY                 	subjects conditions: 1) On Control diet. 2) Normotensive subjects: systolic
ST:STUDY_SUMMARY                 	blood pressure from the low sodium visit is less than 140 and the diastolic
ST:STUDY_SUMMARY                 	blood pressure from low sodium visit is less than 90; 3) For group A: Either the
ST:STUDY_SUMMARY                 	systolic blood pressure from the high sodium visit was greater than 10 mmHg
ST:STUDY_SUMMARY                 	higher than the systolic blood pressure from the low sodium visit, or the
ST:STUDY_SUMMARY                 	diastolic blood pressure from the high sodium visit was greater than 10 mmHg
ST:STUDY_SUMMARY                 	higher than the diastolic blood pressure from the low sodium visit; 3) For group
ST:STUDY_SUMMARY                 	B: The systolic blood pressure from the high sodium visit is within 5 mmHg (i.e.
ST:STUDY_SUMMARY                 	+/- 5) from the systolic blood pressure from the low sodium visit, and the
ST:STUDY_SUMMARY                 	diastolic blood pressure from the high sodium visit is within 5 mmHg from the
ST:STUDY_SUMMARY                 	diastolic blood pressure from the low sodium visit. Use gas chromatography/mass
ST:STUDY_SUMMARY                 	spectrometry (GC/MS) analysis, and liquid chromatography/mass spectrometry
ST:STUDY_SUMMARY                 	(LC/MS)analysis to find the differences of metabolic profiles between the high
ST:STUDY_SUMMARY                 	sodium level and the low sodium level, and compare the metabolic profiles of A
ST:STUDY_SUMMARY                 	with the metabolic profiles of B at the low and high sodium level.
ST:INSTITUTE                     	Mayo Clinic
ST:LAST_NAME                     	Liang
ST:FIRST_NAME                    	Mingyu
ST:ADDRESS                       	Medical College of Wisconsin 8701 Watertown Plank Road Milwaukee, WI 53226
ST:EMAIL                         	mliang@mcw.edu
ST:PHONE                         	414-955-8539
#SUBJECT
SU:SUBJECT_TYPE                  	Human
SU:SUBJECT_SPECIES               	Homo sapiens
SU:TAXONOMY_ID                   	9606
#SUBJECT_SAMPLE_FACTORS:         	SUBJECT(optional)[tab]SAMPLE[tab]FACTORS(NAME:VALUE pairs separated by |)[tab]Additional sample data
SUBJECT_SAMPLE_FACTORS           	DASH200394	ms5956-1	Sodium level:L | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200113	ms5956-2	Sodium level:L | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200214	ms5956-3	Sodium level:L | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200143	ms5956-4	Sodium level:H | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200324	ms5956-5	Sodium level:L | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200373	ms5956-6	Sodium level:L | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200309	ms5956-7	Sodium level:L | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200283	ms5956-8	Sodium level:H | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200222	ms5956-9	Sodium level:H | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200169	ms5956-10	Sodium level:L | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200191	ms5956-11	Sodium level:H | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200149	ms5956-12	Sodium level:L | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200267	ms5956-13	Sodium level:H | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200088	ms5956-14	Sodium level:L | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200230	ms5956-15	Sodium level:H | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200065	ms5956-16	Sodium level:H | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200069	ms5956-17	Sodium level:L | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200084	ms5956-18	Sodium level:H | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200058	ms5956-19	Sodium level:H | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200192	ms5956-20	Sodium level:H | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200057	ms5956-21	Sodium level:L | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200278	ms5956-22	Sodium level:L | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200029	ms5956-23	Sodium level:L | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200119	ms5956-24	Sodium level:L | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200057	ms5956-25	Sodium level:H | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200029	ms5956-26	Sodium level:H | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200037	ms5956-27	Sodium level:H | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200037	ms5956-28	Sodium level:L | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200220	ms5956-29	Sodium level:L | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200271	ms5956-30	Sodium level:L | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200045	ms5956-31	Sodium level:H | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200040	ms5956-32	Sodium level:H | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200128	ms5956-33	Sodium level:L | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200406	ms5956-34	Sodium level:L | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200398	ms5956-35	Sodium level:L | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200160	ms5956-36	Sodium level:H | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200031	ms5956-37	Sodium level:H | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200407	ms5956-38	Sodium level:L | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200105	ms5956-39	Sodium level:L | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200020	ms5956-40	Sodium level:H | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200046	ms5956-41	Sodium level:H | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200338	ms5956-42	Sodium level:H | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200149	ms5956-43	Sodium level:H | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200264	ms5956-44	Sodium level:H | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200067	ms5956-45	Sodium level:H | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200150	ms5956-46	Sodium level:L | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200084	ms5956-47	Sodium level:L | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200264	ms5956-48	Sodium level:L | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200267	ms5956-49	Sodium level:L | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200150	ms5956-50	Sodium level:H | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200381	ms5956-51	Sodium level:L | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200222	ms5956-52	Sodium level:L | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200087	ms5956-53	Sodium level:L | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200067	ms5956-54	Sodium level:L | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200142	ms5956-55	Sodium level:L | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200119	ms5956-56	Sodium level:H | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200346	ms5956-57	Sodium level:L | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200185	ms5956-58	Sodium level:H | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200371	ms5956-59	Sodium level:H | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200290	ms5956-60	Sodium level:H | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200220	ms5956-61	Sodium level:H | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200071	ms5956-62	Sodium level:H | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200024	ms5956-63	Sodium level:H | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200370	ms5956-64	Sodium level:H | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200250	ms5956-65	Sodium level:L | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200333	ms5956-66	Sodium level:L | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200186	ms5956-67	Sodium level:H | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200128	ms5956-68	Sodium level:H | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200258	ms5956-69	Sodium level:L | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200398	ms5956-70	Sodium level:H | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200406	ms5956-71	Sodium level:H | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200142	ms5956-72	Sodium level:L | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200309	ms5956-73	Sodium level:H | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200407	ms5956-74	Sodium level:H | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200233	ms5956-75	Sodium level:L | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200158	ms5956-76	Sodium level:L | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200339	ms5956-77	Sodium level:L | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200020	ms5956-78	Sodium level:L | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200381	ms5956-79	Sodium level:H | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200046	ms5956-80	Sodium level:L | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200346	ms5956-81	Sodium level:H | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200371	ms5956-82	Sodium level:L | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200087	ms5956-83	Sodium level:H | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200185	ms5956-84	Sodium level:L | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200043	ms5956-85	Sodium level:L | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200245	ms5956-86	Sodium level:H | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200186	ms5956-87	Sodium level:L | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200043	ms5956-88	Sodium level:H | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200040	ms5956-89	Sodium level:L | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200088	ms5956-90	Sodium level:H | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200058	ms5956-91	Sodium level:L | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200233	ms5956-92	Sodium level:H | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200250	ms5956-93	Sodium level:H | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200192	ms5956-94	Sodium level:L | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200252	ms5956-95	Sodium level:L | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200045	ms5956-96	Sodium level:L | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200283	ms5956-97	Sodium level:L | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200353	ms5956-98	Sodium level:H | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200230	ms5956-99	Sodium level:L | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200386	ms5956-100	Sodium level:L | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200368	ms5956-101	Sodium level:L | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200227	ms5956-102	Sodium level:L | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200249	ms5956-103	Sodium level:H | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200069	ms5956-104	Sodium level:H | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200334	ms5956-105	Sodium level:L | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200198	ms5956-106	Sodium level:L | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200334	ms5956-107	Sodium level:H | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200252	ms5956-108	Sodium level:H | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200261	ms5956-109	Sodium level:L | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200174	ms5956-110	Sodium level:L | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200065	ms5956-111	Sodium level:L | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200245	ms5956-112	Sodium level:L | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200214	ms5956-113	Sodium level:H | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200031	ms5956-114	Sodium level:L | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200368	ms5956-115	Sodium level:H | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200386	ms5956-116	Sodium level:H | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200237	ms5956-117	Sodium level:H | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200227	ms5956-118	Sodium level:H | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200237	ms5956-119	Sodium level:L | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200249	ms5956-120	Sodium level:L | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200198	ms5956-121	Sodium level:H | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200353	ms5956-122	Sodium level:L | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200174	ms5956-123	Sodium level:H | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200373	ms5956-124	Sodium level:H | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200324	ms5956-125	Sodium level:H | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200142	ms5956-126	Sodium level:H | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200105	ms5956-127	Sodium level:H | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200113	ms5956-128	Sodium level:H | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200158	ms5956-129	Sodium level:H | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200394	ms5956-130	Sodium level:H | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200333	ms5956-131	Sodium level:H | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200338	ms5956-132	Sodium level:L | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200261	ms5956-133	Sodium level:H | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200278	ms5956-134	Sodium level:H | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200258	ms5956-135	Sodium level:H | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200271	ms5956-136	Sodium level:H | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200290	ms5956-137	Sodium level:L | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200169	ms5956-138	Sodium level:H | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200191	ms5956-139	Sodium level:L | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200071	ms5956-140	Sodium level:L | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200370	ms5956-141	Sodium level:L | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200024	ms5956-142	Sodium level:L | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200143	ms5956-143	Sodium level:L | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200339	ms5956-144	Sodium level:H | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200042	ms5956-145	Sodium level:L | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200077	ms5956-146	Sodium level:L | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200085	ms5956-147	Sodium level:L | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200179	ms5956-148	Sodium level:L | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200325	ms5956-149	Sodium level:L | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200403	ms5956-150	Sodium level:L | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200013	ms5956-151	Sodium level:L | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200171	ms5956-152	Sodium level:L | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200276	ms5956-153	Sodium level:L | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200282	ms5956-154	Sodium level:L | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200409	ms5956-155	Sodium level:L | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200042	ms5956-156	Sodium level:H | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200077	ms5956-157	Sodium level:H | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200085	ms5956-158	Sodium level:H | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200179	ms5956-159	Sodium level:H | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200325	ms5956-160	Sodium level:H | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200403	ms5956-161	Sodium level:H | grouping:A	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200013	ms5956-162	Sodium level:H | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200171	ms5956-163	Sodium level:H | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200276	ms5956-164	Sodium level:H | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200282	ms5956-165	Sodium level:H | grouping:B	Sample type=urine; Species=human
SUBJECT_SAMPLE_FACTORS           	DASH200409	ms5956-166	Sodium level:H | grouping:B	Sample type=urine; Species=human
#COLLECTION
CO:COLLECTION_SUMMARY            	The urine samples we have were 24-hour collections occurring in the fourth week
CO:COLLECTION_SUMMARY            	on either the low- or the high-sodium intake level. In total, 120 human samples
CO:COLLECTION_SUMMARY            	(60 subjects, a low-sodium sample and a high-sodium sample for each subject)
CO:COLLECTION_SUMMARY            	will be analyzed.
#TREATMENT
TR:TREATMENT_SUMMARY             	We will analyze urine specimens collected during the Dietary Approaches to Stop
TR:TREATMENT_SUMMARY             	Hypertension – Sodium Study (DASH-Sodium or DASH2) clinical trial. More than
TR:TREATMENT_SUMMARY             	400 participants in the study were divided into two groups. One followed a
TR:TREATMENT_SUMMARY             	common Western diet, while the other group followed the “healthier” DASH
TR:TREATMENT_SUMMARY             	diet. Then each group had three 30 day periods, in random orders, that
TR:TREATMENT_SUMMARY             	corresponded to high, intermediate, or low sodium intakes while eating their
TR:TREATMENT_SUMMARY             	designated diet. The participants had all of their meals prepared and provided
TR:TREATMENT_SUMMARY             	for them during the entire study. It was found that reducing sodium intake
TR:TREATMENT_SUMMARY             	significantly reduced blood pressure especially when on the common Western diet.
TR:TREATMENT_SUMMARY             	We have obtained urine samples and phenotypic data for a subset of the
TR:TREATMENT_SUMMARY             	participants of the DASH2 trial form the NHLBI biospecimen and data repository
TR:TREATMENT_SUMMARY             	BioLINCC. We selected two sub-groups of participants on the Western diet. Group
TR:TREATMENT_SUMMARY             	A (n=31) exhibited large (>12 mmHg) differences in systolic or diastolic
TR:TREATMENT_SUMMARY             	pressure between low- and high-sodium intakes (“salt-sensitive” group).
TR:TREATMENT_SUMMARY             	Group B (n=29) showed similar blood pressure (differences <5 mmHg for both
TR:TREATMENT_SUMMARY             	systolic and diastolic pressures) between low- and high-sodium intakes
TR:TREATMENT_SUMMARY             	(“saltinsensitive” group).
#SAMPLEPREP
SP:SAMPLEPREP_SUMMARY            	2 drops of 6 N HCl was added in every 8 ml urine samples when the 24 hour urine
SP:SAMPLEPREP_SUMMARY            	was collected. All urine samples were stored in -80℃ freezer.
#CHROMATOGRAPHY
CH:CHROMATOGRAPHY_TYPE           	Reversed phase
CH:INSTRUMENT_NAME               	Waters Acquity
CH:COLUMN_NAME                   	Waters Acquity BEH C18 (150 x 2.1mm, 1.7um)
#ANALYSIS
AN:ANALYSIS_TYPE                 	MS
#MS
MS:MS_COMMENTS                   	-
MS:INSTRUMENT_NAME               	Thermo Quantum Ultra
MS:INSTRUMENT_TYPE               	Triple quadrupole
MS:MS_TYPE                       	ESI
MS:ION_MODE                      	POSITIVE
#MS_METABOLITE_DATA
MS_METABOLITE_DATA:UNITS         	uM
MS_METABOLITE_DATA_START
Samples	ms5956-1	ms5956-2	ms5956-3	ms5956-4	ms5956-5	ms5956-6	ms5956-7	ms5956-8	ms5956-9	ms5956-10	ms5956-11	ms5956-12	ms5956-13	ms5956-14	ms5956-15	ms5956-16	ms5956-17	ms5956-18	ms5956-19	ms5956-20	ms5956-21	ms5956-22	ms5956-23	ms5956-24	ms5956-25	ms5956-26	ms5956-27	ms5956-28	ms5956-29	ms5956-30	ms5956-31	ms5956-32	ms5956-33	ms5956-34	ms5956-35	ms5956-36	ms5956-37	ms5956-38	ms5956-39	ms5956-40	ms5956-41	ms5956-42	ms5956-43	ms5956-44	ms5956-45	ms5956-46	ms5956-47	ms5956-48	ms5956-49	ms5956-50	ms5956-51	ms5956-52	ms5956-53	ms5956-54	ms5956-55	ms5956-56	ms5956-57	ms5956-58	ms5956-59	ms5956-60	ms5956-61	ms5956-62	ms5956-63	ms5956-64	ms5956-65	ms5956-66	ms5956-67	ms5956-68	ms5956-69	ms5956-70	ms5956-71	ms5956-72	ms5956-73	ms5956-74	ms5956-75	ms5956-76	ms5956-77	ms5956-78	ms5956-79	ms5956-80	ms5956-81	ms5956-82	ms5956-83	ms5956-84	ms5956-85	ms5956-86	ms5956-87	ms5956-88	ms5956-89	ms5956-90	ms5956-91	ms5956-92	ms5956-93	ms5956-94	ms5956-95	ms5956-96	ms5956-97	ms5956-98	ms5956-99	ms5956-100	ms5956-101	ms5956-102	ms5956-103	ms5956-104	ms5956-105	ms5956-106	ms5956-107	ms5956-108	ms5956-109	ms5956-110	ms5956-111	ms5956-112	ms5956-113	ms5956-114	ms5956-115	ms5956-116	ms5956-117	ms5956-118	ms5956-119	ms5956-120	ms5956-121	ms5956-122	ms5956-123	ms5956-124	ms5956-125	ms5956-126	ms5956-127	ms5956-128	ms5956-129	ms5956-130	ms5956-131	ms5956-132	ms5956-133	ms5956-134	ms5956-135	ms5956-136	ms5956-137	ms5956-138	ms5956-139	ms5956-140	ms5956-141	ms5956-142	ms5956-143	ms5956-144	ms5956-145	ms5956-146	ms5956-147	ms5956-148	ms5956-149	ms5956-150	ms5956-151	ms5956-152	ms5956-153	ms5956-154	ms5956-155	ms5956-156	ms5956-157	ms5956-158	ms5956-159	ms5956-160	ms5956-161	ms5956-162	ms5956-163	ms5956-164	ms5956-165	ms5956-166
Factors	Sodium level:L | grouping:B	Sodium level:L | grouping:B	Sodium level:L | grouping:A	Sodium level:H | grouping:A	Sodium level:L | grouping:B	Sodium level:L | grouping:B	Sodium level:L | grouping:A	Sodium level:H | grouping:A	Sodium level:H | grouping:A	Sodium level:L | grouping:B	Sodium level:H | grouping:A	Sodium level:L | grouping:B	Sodium level:H | grouping:B	Sodium level:L | grouping:A	Sodium level:H | grouping:A	Sodium level:H | grouping:B	Sodium level:L | grouping:A	Sodium level:H | grouping:A	Sodium level:H | grouping:B	Sodium level:H | grouping:A	Sodium level:L | grouping:A	Sodium level:L | grouping:B	Sodium level:L | grouping:A	Sodium level:L | grouping:A	Sodium level:H | grouping:A	Sodium level:H | grouping:A	Sodium level:H | grouping:B	Sodium level:L | grouping:B	Sodium level:L | grouping:A	Sodium level:L | grouping:B	Sodium level:H | grouping:A	Sodium level:H | grouping:A	Sodium level:L | grouping:B	Sodium level:L | grouping:A	Sodium level:L | grouping:A	Sodium level:H | grouping:B	Sodium level:H | grouping:A	Sodium level:L | grouping:B	Sodium level:L | grouping:B	Sodium level:H | grouping:B	Sodium level:H | grouping:B	Sodium level:H | grouping:B	Sodium level:H | grouping:B	Sodium level:H | grouping:A	Sodium level:H | grouping:B	Sodium level:L | grouping:B	Sodium level:L | grouping:A	Sodium level:L | grouping:A	Sodium level:L | grouping:B	Sodium level:H | grouping:B	Sodium level:L | grouping:A	Sodium level:L | grouping:A	Sodium level:L | grouping:B	Sodium level:L | grouping:B	Sodium level:L | grouping:B	Sodium level:H | grouping:A	Sodium level:L | grouping:B	Sodium level:H | grouping:B	Sodium level:H | grouping:B	Sodium level:H | grouping:B	Sodium level:H | grouping:A	Sodium level:H | grouping:A	Sodium level:H | grouping:A	Sodium level:H | grouping:B	Sodium level:L | grouping:B	Sodium level:L | grouping:A	Sodium level:H | grouping:A	Sodium level:H | grouping:B	Sodium level:L | grouping:A	Sodium level:H | grouping:A	Sodium level:H | grouping:A	Sodium level:L | grouping:B	Sodium level:H | grouping:A	Sodium level:H | grouping:B	Sodium level:L | grouping:A	Sodium level:L | grouping:A	Sodium level:L | grouping:B	Sodium level:L | grouping:B	Sodium level:H | grouping:A	Sodium level:L | grouping:B	Sodium level:H | grouping:B	Sodium level:L | grouping:B	Sodium level:H | grouping:B	Sodium level:L | grouping:B	Sodium level:L | grouping:B	Sodium level:H | grouping:A	Sodium level:L | grouping:A	Sodium level:H | grouping:B	Sodium level:L | grouping:A	Sodium level:H | grouping:A	Sodium level:L | grouping:B	Sodium level:H | grouping:A	Sodium level:H | grouping:B	Sodium level:L | grouping:A	Sodium level:L | grouping:B	Sodium level:L | grouping:A	Sodium level:L | grouping:A	Sodium level:H | grouping:A	Sodium level:L | grouping:A	Sodium level:L | grouping:A	Sodium level:L | grouping:A	Sodium level:L | grouping:B	Sodium level:H | grouping:B	Sodium level:H | grouping:A	Sodium level:L | grouping:A	Sodium level:L | grouping:A	Sodium level:H | grouping:A	Sodium level:H | grouping:B	Sodium level:L | grouping:B	Sodium level:L | grouping:B	Sodium level:L | grouping:B	Sodium level:L | grouping:A	Sodium level:H | grouping:A	Sodium level:L | grouping:A	Sodium level:H | grouping:A	Sodium level:H | grouping:A	Sodium level:H | grouping:B	Sodium level:H | grouping:B	Sodium level:L | grouping:B	Sodium level:L | grouping:B	Sodium level:H | grouping:A	Sodium level:L | grouping:A	Sodium level:H | grouping:B	Sodium level:H | grouping:B	Sodium level:H | grouping:B	Sodium level:H | grouping:B	Sodium level:H | grouping:B	Sodium level:H | grouping:B	Sodium level:H | grouping:A	Sodium level:H | grouping:B	Sodium level:H | grouping:A	Sodium level:L | grouping:B	Sodium level:H | grouping:B	Sodium level:H | grouping:B	Sodium level:H | grouping:A	Sodium level:H | grouping:B	Sodium level:L | grouping:B	Sodium level:H | grouping:B	Sodium level:L | grouping:A	Sodium level:L | grouping:A	Sodium level:L | grouping:B	Sodium level:L | grouping:A	Sodium level:L | grouping:A	Sodium level:H | grouping:B	Sodium level:L | grouping:A	Sodium level:L | grouping:A	Sodium level:L | grouping:A	Sodium level:L | grouping:A	Sodium level:L | grouping:A	Sodium level:L | grouping:A	Sodium level:L | grouping:B	Sodium level:L | grouping:B	Sodium level:L | grouping:B	Sodium level:L | grouping:B	Sodium level:L | grouping:B	Sodium level:H | grouping:A	Sodium level:H | grouping:A	Sodium level:H | grouping:A	Sodium level:H | grouping:A	Sodium level:H | grouping:A	Sodium level:H | grouping:A	Sodium level:H | grouping:B	Sodium level:H | grouping:B	Sodium level:H | grouping:B	Sodium level:H | grouping:B	Sodium level:H | grouping:B
Histidine	671.2	1021.5	918.2	1116.6	580.4	390.3	517.4	809.4	2769.6	510.2	341.0	1147.3	1541.6	147.5	1189.6	978.3	144.0	485.5	899.7	67.3	1475.1	257.3	1326.0	2560.7	2111.9	1194.7	407.3	408.9	339.6	527.7	406.5	588.9	434.8	154.3	655.7	2133.7	460.9	200.6	545.4	1577.5	1378.7	368.2	2036.8	1016.5	5889.5	848.3	297.2	613.5	3071.0	977.1	219.4	5370.8	654.4	4349.7	142.0	3313.8	1131.1	706.4	1450.5	1286.4	764.0	434.7	435.9	621.0	425.0	539.6	349	737	265	290	208	1061	275	482	190	1267	425	636	132	266	678	788	424	918	487	938	692	157	416	51	108	205	168	330	264	84	138	778	1157	156	382	801	826	133	167	693	242	436	344	725	1238	451	436	214	141	404	312	522	479	841	514	594	348	179	276	91	14	464	1062	83	409	107	88	177	650	540	598	373	122	117	317	182	1071	526	919	42	57	505	419	1177	812	1230	398	1179	1440	1680	23	76	2128	177	1154	555	2703	71	888	2301
Hydroxyproline	2.1	2.1	8.0	5.2	1.9	0.5	3.1	4.3	11.3	3.2	0.7	4.9	15.3	9.6	2.4	3.9	3.3	3.1	6.2	0.1	9.4	8.4	6.5	34.6	6.8	7.8	1.7	1.4	3.0	1.0	1.7	8.9	1.6	0.5	2.2	685.3	2.1	1.8	1.8	19.4	3.3	3.0	4.0	4.6	21.9	4.2	1.0	3.6	12.5	6.3	2.1	14.7	2.3	5.3	0.5	87.8	8.1	17.4	15.3	2.2	6.3	11.2	5.8	1.3	1.1	1.1	2.5	2.3	3.0	1.2	0.5	275.1	0.2	2.6	3.8	10.7	1.5	18.2	3.7	0.5	1.8	7.1	2.1	14.7	1.7	20.9	0.8	1.6	0.5	17.3	20.1	7.3	1.5	3.4	2.1	0.8	1.0	15.9	4.9	5.3	12.0	1.0	7.7	4.6	0.8	2.1	0.8	2.2	9.9	18.8	0.0	2.5	2.8	1.4	7.1	3.8	1.6	1.0	0.9	3.8	2.5	8.8	7.0	0.1	4.6	2.2	5.3	2.2	5.2	1.6	1.0	0.2	12.9	2.6	8.4	2.2	1.5	2.6	0.9	9.7	1.7	2.5	6.0	1.3	2.6	3.2	3.0	3.0	4.6	2.5	2.9	4.4	11.3	5.5	7.9	9.6	15.9	3.8	10.1	18.6	1.9	3.2	13.5	28.9	4.3	11.0
1-Methylhistidine	822.3	387.3	1507.5	1703.2	1745.7	634.1	2055.7	1547.7	3201.3	2394.8	753.6	1727.1	1659.7	758.5	497.5	1987.8	991.2	1096.9	2273.4	303.5	2795.3	2373.3	7536.5	7174.4	2592.1	4455.3	1003.6	1760.7	2179.9	1551.3	919.8	1994.3	664.1	421.4	1137.7	2464.9	1777.8	1550.1	436.7	117.6	1173.0	951.7	1492.7	1522.6	1879.0	2148.4	663.3	1286.9	324.4	4911.4	1495.2	8243.1	822.0	1167.3	305.6	2990.9	3454.5	549.0	2471.9	3306.3	1986.1	1519.3	1384.8	1220.2	1893.5	1464.7	252.0	1565.9	1335.3	1004.4	780.9	2705.2	1382.4	1848.7	880.4	3577.1	668.4	1069.2	780.2	2511.4	2549.6	1533.6	1250.5	1105.7	2014.6	4054.2	1880.4	567.3	2761.4	1212.3	1932.1	1317.6	1206.4	228.0	1586.4	880.2	3101.8	3636.6	3815.4	2197.3	1990.1	1366.1	1990.6	985.0	224.8	2131.0	119.3	1181.6	1844.1	3084.3	2409.3	2311.5	825.4	479.4	419.3	1570.3	1463.0	1082.7	1975.7	3241.1	1778.5	7607.3	1354.5	225.7	296.7	756.8	476.4	1180.8	2267.2	565.1	1003.1	793.6	736.3	1144.0	1806.2	1248.4	2171.9	1422.5	629.7	1361.6	1154.3	2185.1	4710.0	1016.2	2438.9	1124.6	1523.1	1179.2	616.5	432.1	1231.7	844.8	2015.6	4094.4	2411.7	1391.5	655.9	838.4	4865.0	1119.0	1689.6	1049.3	3409.8	295.3	1426.8	2954.9
3-Methylhistidine	131.5	192.1	389.6	339.6	333.1	94.2	267.8	368.2	943.2	346.4	90.6	202.5	352.9	95.0	480.5	271.5	113.1	5.5	402.8	38.9	585.5	242.1	919.6	837.6	438.5	937.5	249.4	237.0	205.5	212.8	164.0	350.7	254.2	78.9	305.1	424.3	161.3	172.7	65.3	67.2	327.2	145.8	309.9	217.1	329.8	261.6	158.7	195.8	392.6	300.8	178.1	630.6	130.7	403.5	79.1	458.5	442.3	121.3	276.8	377.7	152.6	175.9	99.8	117.1	124.1	186.7	105.1	247.7	127.6	133.7	117.6	410.8	228.9	326.6	125.9	325.9	150.2	222.1	86.6	253.7	395.4	273.8	211.1	360.7	359.0	429.0	285.4	90.7	420.5	148.0	209.8	212.9	181.6	209.5	422.2	132.3	457.3	570.6	843.0	366.7	336.1	251.9	323.2	140.0	112.2	245.0	73.8	210.4	211.7	319.3	370.2	329.5	121.4	154.5	597.0	171.7	164.0	198.5	313.7	417.3	196.6	744.9	411.4	97.8	187.4	112.8	91.5	157.1	278.6	56.8	179.1	120.8	124.2	163.3	207.8	261.8	339.6	291.9	120.0	223.8	155.3	206.3	651.4	191.7	342.0	272.1	211.5	224.8	254.4	173.0	239.3	280.7	346.3	537.2	398.7	499.9	168.2	253.3	728.1	174.3	194.9	196.9	871.2	90.2	341.7	587.1
Asparagine	52.6	46.5	15.4	31.0	56.8	21.9	52.7	73.2	302.3	46.2	18.1	75.0	216.0	14.7	41.8	102.7	11.8	58.3	105.3	13.1	133.0	14.6	153.3	157.2	240.9	155.2	30.9	33.1	43.4	34.6	20.4	15.7	35.9	8.4	56.7	248.0	48.7	29.6	20.1	9.6	66.7	27.3	80.4	91.5	300.9	67.2	35.5	51.0	194.5	76.9	18.3	380.4	37.0	272.9	0.0	22.7	71.3	76.4	42.3	90.0	62.9	20.8	79.3	41.9	42.7	35.2	43.0	83.5	11.9	33.2	19.4	141.9	46.3	61.3	9.5	125.5	53.2	69.5	22.0	47.7	49.9	33.3	51.0	140.1	83.7	149.1	110.1	30.9	68.7	37.1	16.7	11.5	12.5	72.2	57.1	41.3	56.1	43.1	152.8	31.2	79.2	67.3	24.4	23.1	25.9	80.7	33.4	23.1	14.0	143.6	147.5	63.7	24.9	38.0	27.8	18.4	69.6	47.1	60.3	99.9	87.0	127.6	36.0	25.0	45.1	8.6	11.8	46.3	191.0	37.8	46.9	18.3	6.2	31.9	11.2	44.8	63.4	44.2	21.5	18.7	28.1	32.1	89.0	47.8	75.8	18.0	24.9	56.6	53.5	123.0	78.1	143.2	57.1	109.7	119.9	65.2	21.1	33.2	255.4	12.5	112.1	50.0	282.8	5.6	71.4	246.7
Phosphoethanolamine	0.37	2.44	6.21	4.00	2.14	1.18	2.61	3.71	2.65	2.83	0.85	3.67	1.19	0.69	1.32	0.27	1.97	0.94	6.09	0.00	7.41	4.48	20.64	4.86	6.80	9.12	0.65	0.38	3.23	2.31	1.52	2.54	1.83	0.59	1.75	3.85	0.00	0.82	2.25	2.05	2.85	1.68	6.95	0.22	2.32	2.11	0.96	0.91	2.51	5.39	1.06	3.00	1.22	5.51	0.49	2.20	2.18	0.72	3.28	3.62	3.95	1.87	0.03	1.75	0.57	1.48	0.7	0.7	0.3	0.5	0.5	3.9	1.6	1.3	0.4	0.6	1.7	1.9	1.0	1.1	2.1	1.6	0.4	1.9	1.1	2.0	0.3	0.7	2.2	0.2	1.6	0.7	1.5	1.3	1.5	0.6	2.3	5.2	4.2	2.1	1.2	2.8	2.1	2.5	1.8	2.1	0.6	1.6	0.9	1.8	0.3	1.2	1.7	0.5	1.2	0.3	0.8	2.6	3.2	4.0	1.3	7.8	0.3	0.2	0.9	0.0	0.0	1.5	1.0	0.0	0.4	0.1	0.3	3.4	2.5	1.8	2.7	3.5	1.4	1.2	1.9	0.4	5.3	2.1	2.5	1.5	1.7	1.0	2.3	1.7	1.4	3.4	4.7	4.9	2.0	5.3	1.6	3.9	3.4	1.3	0.5	0.6	9.4	1.5	3.3	5.4
Arginine	5.8	4.5	8.0	7.3	13.5	4.7	12.7	13.4	64.4	9.8	3.0	21.7	24.5	5.1	13.9	7.7	4.5	10.4	17.8	2.4	26.0	6.7	23.7	21.4	40.4	15.4	6.5	4.5	12.4	5.2	8.6	3.8	1.8	3.6	22.1	18.2	4.0	4.9	1.8	3.6	19.6	3.5	17.7	10.4	13.9	15.5	4.7	12.8	21.5	24.5	2.2	43.1	5.5	25.1	699.4	4.6	34.0	8.8	34.2	20.1	15.5	4.1	12.9	13.6	3.1	8.4	6.0	13.4	1.4	19.3	4.1	18.6	11.1	10.8	2.4	1.8	3.2	2.5	2.8	7.0	22.1	3.0	10.2	27.3	5.8	36.5	15.5	4.7	12.1	2.9	20.6	3.6	1.1	12.6	15.4	14.3	7.3	10.8	47.8	7.4	20.3	9.1	4.7	2.5	8.7	9.6	6.5	7.0	4.2	18.3	16.8	27.3	3.1	5.1	5.4	4.8	19.0	5.4	14.6	41.3	4.8	28.9	10.2	2.0	8.5	1.3	1.4	3.4	8.5	4.4	10.1	2.4	2.2	7.8	3.3	8.0	12.7	11.7	6.1	9.3	12.7	7.4	29.3	6.1	17.0	5.4	8.9	11.5	12.2	12.2	9.9	15.8	5.4	18.5	7.4	20.9	4.7	12.9	39.4	3.2	6.4	4.6	30.7	1.3	10.8	19.7
Carnosine	0.0	0.0	0.0	0.0	27.5	16.6	38.3	25.3	35.0	21.2	0.0	0.0	32.4	18.2	18.8	45.7	0.0	19.3	0.0	0.0	0.0	69.9	0.0	0.0	0.0	32.1	0.0	19.1	17.2	19.9	0.0	20.1	0.0	0.0	17.8	66.3	43.1	36.7	21.1	26.3	19.0	18.2	48.2	39.9	0.0	0.0	0.0	0.0	53.0	44.0	0.0	49.7	0.0	0.0	0.0	81.5	54.5	0.0	20.8	0.0	0.0	0.0	13.1	0.0	0.0	0.0	20.7	0.0	6.9	4.4	0.0	24.1	29.5	36.0	0.0	0.0	0.0	10.8	0.0	2.9	16.5	19.6	9.5	9.3	5.8	7.2	15.2	2.6	0.0	2.9	0.0	0.0	0.0	0.0	1.9	0.0	0.0	44.4	0.0	18.3	3.2	5.7	31.4	10.7	12.7	48.6	7.9	14.8	31.5	39.8	29.9	25.0	6.0	21.8	6.7	9.9	12.1	4.8	10.1	18.4	58.3	0.0	0.6	2.4	5.6	6.4	5.2	3.8	1.7	0.3	18.1	3.8	5.1	90.2	13.3	18.9	43.1	14.3	6.4	8.4	6.7	26.4	30.3	25.4	27.7	13.8	14.4	20.6	26.9	9.1	57.8	46.0	35.8	37.2	24.7	54.7	4.6	19.6	35.8	29.9	11.4	6.4	116.0	1.5	22.4	28.6
Taurine	894.7	150.3	816.9	1363.2	154.7	188.9	950.7	969.0	799.8	84.3	91.1	514.4	1131.7	169.0	691.6	410.2	76.3	937.0	1244.6	74.4	779.6	393.4	1592.4	1096.6	1217.4	1345.3	556.0	445.8	303.6	658.0	279.1	750.6	760.3	227.2	208.2	1094.2	260.1	400.1	53.5	233.8	642.3	549.7	624.3	890.8	1235.1	548.1	601.5	516.4	1244.7	655.1	431.6	170.5	374.1	836.5	242.2	1022.5	1136.9	534.5	496.1	1183.9	459.1	183.0	631.4	308.0	59.0	511.3	367	571	222	69	179	952	549	601	610	608	185	221	489	237	511	268	379	1583	254	1331	589	222	612	138	813	593	253	312	1984	129	936	1439	2842	315	844	624	460	166	383	392	170	572	300	1731	428	1017	702	72	444	368	919	426	866	861	456	1224	995	299	113	279	246	155	516	371	507	248	402	440.6	659.9	327.8	777.2	145.7	62.7	208.5	254.8	327.5	1485.2	481.0	1869.5	215.6	456.6	330.6	887.7	270.6	373.3	1170.8	1235.4	689.1	1271.6	2828.0	396.7	524.0	1580.4	468.7	369.1	649.1	1706.7	291.3	816.9	1996.2
Anserine	19.2	0.0	10.9	23.5	39.5	12.2	20.4	13.4	28.0	24.7	31.6	75.4	55.9	28.4	0.0	13.9	11.0	18.5	42.8	10.5	11.5	479.4	1383.5	353.5	73.9	36.8	11.7	18.9	12.8	61.8	19.6	181.1	10.5	0.0	0.0	24.0	66.4	108.6	41.9	0.0	27.0	30.9	30.6	37.2	25.6	60.4	23.6	32.3	0.0	415.6	25.1	59.2	0.0	0.0	0.0	32.5	121.4	0.0	66.1	30.2	24.4	26.6	26.5	25.0	23.9	42.8	8.3	38.0	36.8	44.6	15.2	60.5	75.5	76.4	82.9	141.9	6.3	69.7	20.7	127.4	26.7	21.5	19.6	43.6	58.6	97.6	59.4	8.6	259.8	28.0	115.3	127.3	9.7	7.6	21.5	29.3	70.0	30.5	93.7	101.0	92.2	79.6	188.8	7.3	5.8	254.8	6.9	100.9	116.2	182.6	210.5	113.6	18.2	68.6	9.6	152.5	180.9	40.4	194.8	301.9	317.5	447.2	91.0	18.0	3.2	78.6	3.7	23.0	53.8	26.6	103.8	47.7	19.0	177.8	119.3	21.5	166.7	25.3	1.2	82.2	49.5	206.0	274.1	80.5	197.2	68.7	149.3	102.0	59.0	4.0	183.4	99.1	111.1	388.8	77.9	77.6	13.5	26.0	392.2	87.5	93.0	8.7	264.8	0.0	36.8	36.8
Serine	211.7	177.1	0.0	4.9	219.3	48.6	172.8	240.9	962.9	200.3	98.8	204.2	591.3	89.6	198.5	230.4	28.8	185.7	465.4	35.4	473.4	75.1	465.4	771.3	664.3	612.0	123.7	109.0	158.1	94.5	68.1	130.5	93.6	43.3	174.2	529.0	132.3	158.5	31.5	4.5	207.5	113.7	210.5	345.9	1301.5	204.3	85.6	239.5	595.6	181.4	74.2	865.1	110.9	1167.2	5.1	161.5	259.8	178.2	83.6	260.4	206.7	5.1	209.4	128.1	100.7	169.7	132.2	161.3	1.9	109.9	67.7	327.0	147.4	293.6	1.6	130.4	83.3	130.9	72.7	143.7	214.6	97.6	143.5	376.0	145.8	398.0	183.7	81.9	259.8	98.6	22.3	1.1	1.2	155.4	221.6	101.7	149.7	79.3	400.9	89.6	17.3	185.5	5.6	101.8	133.3	242.2	116.9	159.5	3.0	379.5	368.4	190.6	2.7	90.7	7.2	4.7	176.0	157.8	155.7	417.3	245.3	558.4	92.5	45.6	155.6	0.7	0.5	149.8	424.0	168.7	174.7	58.5	1.9	100.9	103.4	149.1	174.1	147.1	94.1	31.8	108.7	160.9	249.8	81.4	217.1	4.9	70.7	213.1	219.8	340.3	209.5	382.0	244.0	292.9	261.9	424.0	4.7	99.0	786.3	3.6	226.5	157.6	777.6	1.8	218.0	798.3
Glutamine	256.5	257.4	265.5	303.6	429.3	101.7	256.4	386.1	1684.2	242.4	150.2	485.8	782.2	118.0	336.2	422.6	91.2	282.1	815.9	62.8	764.5	226.8	452.6	928.4	1163.6	578.6	179.8	145.3	223.9	153.9	140.5	257.8	125.9	54.4	271.7	644.7	141.7	231.6	83.7	298.4	346.9	198.3	556.2	448.5	1412.3	225.5	163.3	291.6	742.5	242.7	88.9	1558.7	153.4	1241.4	33.0	718.3	393.5	307.4	475.4	361.6	290.8	98.2	190.7	212.2	161.3	212.5	148.5	267.5	91.3	177.1	78.8	347.1	219.3	390.6	114.7	539.9	172.5	442.5	92.1	218.0	290.6	327.5	235.9	666.1	253.2	616.0	287.9	82.4	293.4	132.0	261.9	154.9	149.6	231.2	449.9	190.0	240.1	740.1	669.9	181.8	287.2	259.6	290.2	116.0	120.4	309.8	171.0	270.6	151.9	623.3	571.5	310.2	198.1	141.7	265.2	124.6	338.5	243.5	303.4	631.7	302.7	656.7	332.6	96.8	352.9	24.2	98.8	255.7	577.7	204.1	239.1	87.4	98.9	172.2	315.4	275.5	306.1	262.7	155.4	85.3	174.1	132.5	360.6	187.4	325.0	155.5	84.7	235.7	228.8	482.2	309.8	638.1	337.6	606.0	703.5	699.7	226.0	124.8	1207.3	134.2	424.4	191.2	1225.1	14.4	451.4	1224.3
Ethanolamine	126.0	212.7	236.8	299.9	375.9	91.2	260.1	264.4	479.0	308.7	107.1	272.0	258.3	82.9	312.4	356.2	119.7	231.6	495.9	78.3	456.6	226.7	398.5	503.7	423.9	453.9	163.0	159.3	192.5	148.3	179.1	238.9	149.9	86.7	276.4	293.1	165.5	117.0	58.7	174.3	192.6	107.9	306.3	237.1	633.9	300.1	119.8	191.1	273.1	357.0	106.4	608.4	155.2	736.9	37.2	298.5	195.4	159.8	291.9	324.2	231.4	191.6	58.1	130.6	128.8	127.4	169	177	112	127	92	244	239	234	0	197	111	251	68	132	225	281	201	421	152	297	166	112	282	121	193	117	159	202	393	164	249	494	692	268	374.6	236.7	220.3	205.8	132.3	198.0	146.2	172.4	199.1	427.4	544.0	273.7	140.5	142.4	269.5	150.7	203.4	169.3	229.9	280.7	181.8	366.9	304.5	82.6	298.7	49.5	19.4	219.0	241.7	77.4	118.1	53.7	164.0	198.4	196.3	295.3	207.4	324.1	161.8	154.1	158.0	108.5	403.0	122.5	371.1	250.0	72.5	166.2	260.1	136.9	194.1	267.9	399.7	377.7	389.8	514.4	0.0	130.4	611.8	203.6	135.1	173.4	725.1	118.3	255.0	690.0
Glycine	1706.6	1238.4	582.4	1781.1	899.5	175.4	465.8	754.8	4280.8	364.3	436.2	467.0	2327.3	810.5	399.1	1846.4	209.5	688.8	2580.3	112.9	1986.7	460.4	1652.8	7772.7	2195.4	2815.1	649.3	468.0	430.0	376.3	322.3	841.3	422.4	155.6	811.7	5370.6	450.4	853.5	148.3	846.1	826.3	417.6	475.5	2653.2	6803.1	855.3	325.1	2268.7	2709.1	850.4	258.5	3710.6	430.4	5834.1	258.1	4687.3	941.3	1426.2	2181.2	779.1	707.6	474.9	945.3	437.3	477.2	274.8	433	654	823	407	202	4215	414	1516	250	1778	282	1733	341	547	604	1256	489	2922	593	874	649	273	843	1254	1317	390	535	630	1044	387	465	1361	854	995	1782.7	368.6	1020	433	366	857	690	829	1442	1837	1705	327	378	293	1419	605	700	310	592	839	1742	1386	880	172	820	254	286	917	1894	1484	309	185	969	308.4	1766.3	1039.8	586.4	359.5	468.2	468.2	415.1	793.6	2923.6	235.4	1146.4	428.8	192.6	1041.1	1146.2	1380.0	1120.4	1141.6	2051.4	1148.3	5544.7	2683.4	964.6	320.6	3733.7	664.7	1299.2	673.0	2311.8	719.1	908.3	7381.2
Aspartic Acid	3.5	1.4	1.1	5.4	1.7	0.0	1.7	1.9	3.9	6.4	0.0	0.0	4.0	0.4	4.3	15.3	1.2	1.9	2.0	0.0	4.9	0.3	3.6	93.4	6.6	2.7	0.7	0.9	1.5	0.2	2.6	0.7	0.7	0.1	3.4	1.3	1.5	0.4	0.0	1.7	2.3	0.4	1.3	2.2	39.9	2.2	1.4	1.6	2.8	2.7	0.7	7.5	2.7	29.1	0.4	55.3	1.3	0.4	2.0	2.7	2.5	4.5	2.1	3.9	1.9	6.9	0.9	1.8	1.9	2.1	0.5	1.3	1.0	1.1	1.1	2.7	0.7	4.9	1.2	1.1	1.5	1.3	1.2	2.0	1.3	0.8	1.1	1.8	1.9	1.9	71.2	2.7	0.7	0.8	19.2	0.6	1.3	15.3	6.5	13.4	57.7	0.8	2.2	5.4	1.4	2.8	2.3	23.5	11.0	3.6	4.7	0.9	1.1	0.5	6.0	5.1	1.7	0.4	2.1	4.6	4.2	41.7	5.9	0.6	1.3	0.6	4.1	7.5	2.2	1.3	2.4	0.3	7.4	0.6	4.6	4.7	0.4	2.8	0.1	1.2	2.6	2.6	1.2	0.0	3.1	2.3	1.1	2.6	3.6	29.1	0.9	1.0	2.7	1.9	27.4	73.3	1.9	1.7	11.8	5.0	1.6	0.9	3.7	3.4	0.9	13.2
Sarcosine	0.9	0.4	0.3	0.5	0.5	0.0	0.3	0.3	5.0	0.5	0.0	2.9	0.7	0.4	0.0	0.0	0.8	0.0	2.1	0.0	1.6	0.8	0.0	4.1	1.5	0.8	0.2	0.5	0.9	0.0	0.0	0.0	0.0	0.0	0.6	17.1	0.4	0.0	0.0	1.2	0.0	0.3	2.4	0.7	2.1	0.3	0.0	0.3	1.0	0.9	0.0	4.6	0.3	1.8	0.0	3.8	1.9	0.0	1.3	1.0	0.9	0.0	0.0	0.0	0.0	0.3	1.1	0.1	0.8	0.2	0.1	10.2	0.5	0.6	0.1	0.5	0.3	2.7	0.4	0.0	0.3	0.8	0.3	0.7	0.2	3.1	0.0	0.7	0.0	0.5	1.0	0.4	0.4	1.1	2.7	0.2	0.6	1.7	1.6	0.3	0.2	0.0	2.0	0.4	0.0	0.0	0.0	1.4	0.7	1.3	0.0	1.4	0.2	0.8	0.2	0.0	0.0	0.0	0.0	1.9	0.2	1.6	0.4	0.0	0.4	0.0	0.0	0.0	0.2	0.2	0.1	0.0	0.2	0.7	2.5	0.3	0.8	0.7	0.2	0.1	0.3	0.0	0.3	0.3	0.6	0.2	0.1	0.6	0.3	0.1	0.5	0.8	1.7	2.5	0.9	1.9	0.5	0.9	2.9	2.4	0.2	0.0	1.7	0.0	2.2	1.7
Citrulline	2.7	7.5	0.1	0.5	5.2	1.7	7.5	12.3	51.1	4.2	2.5	14.9	9.8	2.8	8.9	8.2	0.0	8.2	6.4	0.1	22.8	9.1	20.9	33.5	55.0	20.2	1.5	1.5	5.4	2.6	5.5	0.0	2.4	0.8	5.2	30.9	2.6	1.7	5.3	4.0	3.9	3.0	20.6	4.4	28.8	6.5	2.7	1.1	9.9	8.3	0.9	35.7	3.0	19.2	0.0	34.3	6.7	6.6	25.8	6.5	12.5	0.0	12.4	5.3	2.3	9.4	3.2	4.9	0.0	1.8	1.1	21.5	5.3	3.1	0.0	25.0	2.3	8.2	1.3	2.3	4.1	11.4	4.5	15.4	7.3	51.7	13.3	1.0	1.7	1.9	4.7	1.1	0.0	5.6	6.7	6.0	2.0	11.5	9.9	1.5	5.1	2.5	21.2	0.0	1.0	3.8	1.4	5.4	0.0	10.9	7.0	14.5	3.0	0.9	4.1	0.0	10.7	1.4	8.7	16.1	2.3	21.7	2.9	0.0	1.8	0.0	5.5	7.9	24.0	0.4	11.1	0.0	0.0	4.0	0.2	5.8	4.0	3.2	2.3	-0.2	2.4	4.5	9.1	4.9	7.0	2.1	1.3	3.4	5.4	7.2	3.8	12.6	6.5	13.9	14.5	18.3	6.8	6.7	33.8	2.7	9.9	4.1	23.7	0.0	11.4	29.3
Glutamic Acid	11.6	15.1	13.3	29.1	20.5	6.3	15.7	18.6	32.3	12.9	8.3	14.3	30.6	4.1	40.5	53.1	18.8	13.1	26.7	7.6	58.3	18.4	32.2	82.1	50.4	33.7	10.4	12.2	15.7	11.3	29.7	42.7	10.9	5.3	25.0	19.9	12.0	5.8	3.1	19.8	21.8	17.3	18.7	17.6	31.8	16.7	11.1	17.5	26.3	18.8	10.5	51.5	28.9	27.3	5.1	90.4	18.1	13.9	15.1	22.4	14.3	24.5	12.0	10.2	13.0	13.3	19.5	12.4	41.1	9.0	5.5	13.9	9.6	11.7	121.8	17.3	7.3	22.1	13.5	15.2	14.7	22.4	13.4	21.7	18.9	18.7	16.8	29.2	17.2	6.0	20.2	125.6	11.7	14.1	20.3	7.1	15.5	64.7	52.6	38.3	69.4	16.0	182.4	31.8	10.6	33.9	12.5	15.7	36.1	26.1	47.1	13.1	8.6	11.8	24.7	77.6	29.3	11.5	28.9	33.2	31.7	44.0	71.3	6.5	12.7	3.7	8.6	40.6	25.1	7.9	11.9	10.5	27.2	11.9	109.9	27.2	12.6	14.8	9.9	26.4	25.4	22.8	16.4	7.3	29.2	13.3	12.1	36.4	15.8	20.9	17.2	14.2	13.8	19.6	40.4	40.5	11.0	32.4	31.6	11.5	24.1	15.4	28.3	11.4	15.8	69.0
beta-Alanine	13.1	0.9	21.5	8.3	2.1	3.8	36.5	39.6	14.7	2.6	5.5	32.5	40.9	24.7	3.5	9.6	1.0	24.4	46.6	0.4	19.7	35.6	218.6	80.8	45.5	38.2	10.2	10.1	9.8	22.0	12.1	32.9	8.7	6.4	3.4	62.9	12.2	24.8	2.2	2.8	10.4	11.7	40.9	36.1	19.4	16.6	11.8	15.6	26.0	56.6	16.4	8.5	13.1	5.8	4.3	40.7	50.0	4.7	9.5	42.5	18.8	7.4	14.6	10.1	5.3	16.5	4.9	18.4	8.9	1.1	6.3	37.8	10.5	11.1	11.7	13.9	3.6	3.7	14.1	4.8	4.1	3.4	8.5	22.8	17.9	75.7	40.5	6.0	35.8	10.1	74.0	16.9	9.4	12.1	8.8	8.0	50.4	45.1	19.4	6.6	16.2	11.6	3.8	1.7	1.2	18.0	0.5	25.6	17.6	22.9	6.0	38.8	17.3	1.1	3.5	8.3	24.1	11.4	27.9	9.5	20.0	81.9	5.5	7.0	0.3	5.2	2.0	3.9	8.8	6.4	12.8	4.8	13.7	21.5	19.2	2.7	52.8	5.7	0.1	6.7	5.3	7.0	12.7	22.5	42.6	6.6	30.2	31.6	7.9	2.8	12.0	39.1	38.0	36.5	28.7	62.4	5.0	19.6	107.5	2.7	8.8	4.1	48.5	3.0	15.1	30.3
Threonine	129.7	71.4	77.0	71.0	161.6	27.9	62.1	129.6	811.1	98.5	37.1	120.5	350.1	44.1	126.5	164.2	17.1	99.9	202.2	16.6	325.9	87.5	204.0	421.7	445.5	243.7	55.0	48.9	62.6	58.4	57.8	83.5	49.5	16.0	112.5	356.9	66.0	60.4	19.6	68.6	94.3	50.3	155.3	190.0	554.8	88.4	46.5	136.0	266.5	103.2	21.5	749.1	45.8	445.2	9.3	527.8	115.5	133.8	248.3	114.0	112.1	7.5	85.4	69.9	102.5	55.8	61.8	80.3	34.8	70.4	23.1	185.6	46.0	95.6	0.0	379.7	41.8	153.7	20.7	52.8	79.9	134.3	58.0	216.9	65.0	240.7	126.1	35.5	73.4	43.8	90.8	0.0	81.7	93.6	77.9	62.3	45.6	233.8	161.5	51.0	72.4	83.5	142.7	27.6	27.4	149.2	38.3	63.4	60.9	189.0	205.3	76.9	51.7	34.9	68.1	20.8	83.1	77.3	67.5	246.2	116.8	276.9	70.2	22.3	96.0	0.8	0.0	55.8	382.5	97.6	61.2	22.8	35.6	53.6	89.5	108.8	83.4	81.8	35.7	13.5	45.5	47.6	110.7	49.3	100.0	1.2	33.0	103.6	90.4	157.3	102.3	254.0	102.0	174.6	289.9	248.1	1.3	44.0	425.3	31.1	131.7	77.7	477.2	1.0	147.6	431.1
Alanine	226.5	145.4	209.8	349.2	225.6	57.6	244.9	237.8	541.1	126.2	50.2	179.5	452.5	55.3	127.0	266.2	42.9	179.9	307.2	54.3	363.8	147.4	214.2	521.3	438.9	231.3	117.4	94.6	113.3	89.8	106.8	150.7	98.1	34.8	178.8	751.4	85.4	124.1	92.3	113.9	221.9	73.1	253.5	214.3	694.3	120.5	94.9	149.4	474.0	140.5	65.2	671.2	111.7	529.5	31.8	696.9	212.5	203.7	343.2	328.6	167.2	93.6	76.4	91.3	111.2	114.0	80.9	173.2	93.9	104.3	41.1	521.7	173.5	195.8	67.5	289.6	66.1	354.7	56.5	140.8	171.0	232.4	108.1	300.2	113.8	349.1	188.1	88.4	142.5	75.5	205.8	87.2	114.6	132.7	294.2	107.7	138.9	413.6	349.4	122.9	224.3	173.6	220.4	64.4	53.2	134.6	96.1	155.2	203.0	391.4	407.9	118.0	127.4	41.1	143.7	80.5	150.8	121.1	141.6	242.3	130.9	303.1	218.7	50.7	173.9	39.5	112.2	183.7	279.0	103.8	135.3	30.1	113.1	104.3	269.0	169.3	235.8	149.1	60.9	116.3	101.9	67.8	471.7	77.8	160.6	136.9	53.9	152.5	138.7	175.4	175.4	256.2	296.1	469.1	497.8	320.8	137.6	91.8	564.1	115.2	133.9	111.7	603.2	67.1	260.9	620.1
gamma-Amino-N-butyric-acid	1.03	0.95	1.35	2.63	2.12	0.35	0.77	1.10	1.34	2.18	0.08	1.81	1.54	0.45	0.07	2.49	0.97	1.01	3.24	0.00	4.10	1.95	2.84	5.08	2.81	2.70	0.43	0.16	0.50	0.55	0.36	0.40	0.75	0.05	1.85	0.90	0.22	0.83	1.00	0.31	0.84	0.09	2.04	0.72	1.77	1.73	0.77	0.91	2.07	1.02	0.32	1.17	0.83	2.49	0.24	80.95	0.34	1.10	1.81	0.00	0.72	0.60	0.39	0.40	0.85	0.32	0.72	1.04	3.38	1.04	0.39	1.95	1.38	1.92	0.35	2.30	0.31	3.19	0.53	0.99	2.35	2.26	1.40	3.38	1.14	1.89	1.64	1.05	1.44	0.59	1.40	0.35	3.37	0.66	5.46	0.82	2.76	3.00	4.88	1.95	2.56	1.47	1.20	23.47	0.52	3.03	0.33	0.95	2.44	3.26	2.93	1.28	0.58	0.95	2.00	1.54	1.71	0.70	0.90	1.34	1.75	6.39	3.61	0.51	1.41	0.48	1.89	0.47	1.10	0.41	0.50	0.11	4.51	1.72	7.42	1.60	1.55	3.33	1.33	1.75	1.23	2.26	6.90	0.53	3.45	3.43	0.84	1.45	2.13	1.55	2.43	2.43	5.23	3.98	3.46	4.69	1.81	2.86	7.39	1.10	1.32	1.16	6.21	1.15	2.12	4.59
alpha-Aminoadipic-acid	8.2	16.2	26.9	24.3	25.3	18.2	22.8	24.5	47.3	17.5	4.2	37.9	49.6	5.7	7.8	31.1	5.2	19.7	42.3	1.1	80.9	34.4	60.5	78.1	77.0	48.5	13.6	13.9	15.0	18.6	23.6	20.0	10.5	4.9	19.7	60.8	19.8	13.3	4.0	21.2	26.6	11.4	30.8	27.6	45.4	15.2	12.8	19.6	25.9	33.3	6.5	54.2	17.7	38.7	6.4	52.4	55.5	11.9	22.2	34.8	14.1	7.5	8.5	10.3	9.7	15.4	13.2	19.5	12.0	8.7	7.2	63.4	17.9	35.6	12.5	42.7	17.2	21.0	7.0	16.5	36.8	19.6	23.5	30.7	17.2	72.5	23.0	8.7	18.8	7.9	28.2	16.2	10.9	16.0	14.3	17.4	22.7	56.3	24.6	25.8	24.5	29.0	18.2	6.7	15.2	28.8	6.1	10.9	19.7	47.9	45.2	42.7	17.6	20.2	10.3	15.7	21.8	22.8	30.2	21.4	30.5	56.3	14.4	21.5	18.9	8.6	6.1	19.4	44.6	5.5	17.3	7.0	9.5	14.7	23.3	16.2	28.6	13.3	5.5	8.0	12.0	9.0	29.6	20.1	29.9	21.9	9.1	17.8	15.4	12.4	31.9	29.4	29.8	61.0	25.9	47.9	26.5	17.1	42.2	7.0	15.1	17.9	83.5	5.9	37.4	51.4
beta-Aminoisobutyric-acid	141.0	36.4	57.3	20.6	76.7	26.6	21.8	184.9	60.9	707.9	3.3	437.5	966.4	12.2	77.0	34.9	173.6	35.6	253.2	73.1	75.3	55.7	101.9	104.9	115.0	137.8	26.6	34.8	9.7	18.5	20.6	121.9	48.3	12.9	43.4	65.4	17.0	24.5	1.9	20.6	15.0	33.0	379.7	61.3	82.5	56.8	24.0	42.2	1245.8	59.3	19.5	78.9	31.3	144.0	9.9	54.2	68.2	47.4	24.0	74.5	11.6	48.1	9.4	25.5	43.1	377.0	37.1	56.4	6.5	7.8	20.6	50.0	19.0	55.5	19.2	58.5	14.4	26.5	16.3	13.3	42.9	21.7	51.4	186.0	76.3	52.7	76.8	20.8	172.3	16.4	125.3	82.7	56.6	228.0	49.9	16.4	247.5	97.4	239.5	18.0	12.6	19.6	7.6	366.9	2.7	73.4	1.6	33.4	80.8	30.1	55.4	53.5	28.6	9.1	6.0	12.4	31.2	21.1	41.3	13.5	68.5	118.6	13.9	26.9	65.1	19.3	2.1	27.5	64.8	114.7	352.7	18.3	54.0	36.2	15.2	22.8	57.9	828.4	3.9	28.3	23.3	21.1	20.0	15.2	23.1	24.2	455.2	77.5	118.9	85.0	88.1	82.2	85.2	64.4	87.7	43.6	33.6	536.1	275.3	53.8	122.4	58.7	174.7	13.9	47.5	138.5
Proline	5.4	6.0	7.9	10.2	7.6	1.8	8.4	9.0	22.4	8.3	1.8	7.2	18.2	2.7	9.6	15.7	2.9	9.0	10.8	1.4	20.2	10.5	20.8	37.0	16.0	21.5	4.1	5.0	5.3	4.2	4.2	6.3	4.5	1.4	8.0	763.0	4.9	3.4	1.7	2.5	9.2	3.2	7.1	7.9	16.3	7.2	5.4	6.6	16.8	7.6	5.8	28.6	4.9	18.9	0.7	23.8	7.7	5.6	26.1	9.5	6.2	7.1	4.6	2.6	3.8	4.8	3.6	7.2	4.0	4.6	2.9	480.2	7.1	8.4	3.8	8.8	3.3	12.3	6.1	5.8	9.7	23.8	6.7	11.6	7.3	14.7	7.9	2.6	7.6	3.8	12.7	10.7	3.0	4.5	13.3	5.3	8.8	19.7	30.7	9.1	11.6	6.5	7.1	6.3	3.8	7.8	4.7	6.9	4.8	12.6	21.4	9.5	4.3	2.5	9.2	6.0	7.9	4.1	7.4	17.9	4.5	25.9	16.2	1.8	5.5	0.9	2.1	7.3	11.3	3.3	8.2	1.1	4.4	7.3	2.9	7.6	5.8	8.6	3.3	7.6	3.5	6.5	12.7	2.9	8.1	8.1	5.1	6.5	8.6	6.9	5.8	8.1	13.8	7.5	16.1	15.6	6.3	5.9	17.7	7.3	4.8	4.7	22.0	4.1	6.7	24.0
Hydroxylysine 1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.1	0.0	0.0	0.1	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.2
Hydroxylysine 2	1.6	3.0	8.5	6.1	1.8	0.2	5.9	1.6	7.3	0.9	1.2	9.5	9.7	0.4	2.3	2.2	0.1	1.0	2.1	-0.2	5.6	2.4	2.5	2.6	7.8	10.6	1.3	0.5	1.4	1.0	1.1	0.4	0.5	1.8	1.5	9.7	4.0	3.6	3.0	7.2	2.5	0.7	3.5	2.1	7.3	1.9	1.1	2.0	6.2	2.1	0.0	7.8	2.6	1.1	1.9	9.0	14.6	3.5	11.3	2.2	2.7	7.8	5.3	2.9	0.4	2.0	1.0	1.5	6.4	0.6	0.5	3.5	2.0	1.5	3.4	2.5	2.2	3.3	0.1	0.9	2.8	4.9	3.4	2.9	1.9	5.0	1.5	0.4	0.3	1.2	1.9	2.1	4.3	2.3	2.0	1.2	0.5	7.9	1.9	3.0	2.6	0.9	4.5	2.5	3.5	0.5	1.9	2.0	4.8	12.8	0.8	1.4	4.7	4.2	3.0	2.3	0.9	0.4	1.3	1.9	0.5	1.3	1.2	0.1	1.9	0.6	2.9	1.7	1.4	0.5	0.6	0.0	1.7	1.9	9.4	0.5	2.2	1.1	1.0	1.3	2.8	0.8	0.8	1.7	1.6	2.3	1.7	1.1	2.0	1.7	1.9	4.0	2.1	2.8	3.1	3.7	36.6	2.1	4.2	0.6	1.3	2.0	4.2	8.0	2.6	5.8
alpha-Amino-N-butyric-acid	2.1	4.7	7.3	3.7	5.6	1.6	4.3	10.1	11.5	4.1	2.2	5.3	9.1	1.5	3.7	4.3	1.5	4.2	12.2	0.9	11.5	10.2	8.1	13.9	12.4	11.7	3.0	3.2	3.5	3.2	3.2	4.1	1.6	1.0	4.3	10.9	4.0	3.7	0.9	3.0	6.6	3.2	5.9	5.5	12.6	3.4	2.6	4.7	6.0	3.8	1.5	11.9	2.4	16.5	0.9	10.1	10.0	6.2	8.4	6.7	3.8	2.6	2.5	3.5	2.6	3.8	2.8	3.2	2.7	2.5	1.4	7.8	3.8	6.4	0.8	7.5	2.0	4.5	1.0	4.1	5.8	6.0	3.4	13.5	5.7	8.2	4.7	2.4	4.7	2.0	4.8	4.2	3.3	3.4	6.3	2.3	8.8	12.2	13.2	3.6	8.0	5.1	9.3	2.9	2.4	5.2	1.8	5.4	3.8	9.7	6.7	4.5	4.2	2.4	2.5	2.4	4.0	3.5	4.0	6.6	20.1	8.5	7.3	1.4	4.1	0.5	1.4	3.4	6.1	1.4	3.2	1.3	3.5	2.7	8.4	4.1	4.4	3.7	2.0	1.8	3.0	2.7	5.9	1.7	5.0	3.8	1.3	3.2	2.8	4.8	6.4	8.0	5.7	10.7	10.1	7.7	4.2	2.8	13.3	3.8	5.5	3.5	17.6	0.3	6.9	21.5
Ornithine	1.8	7.1	2.0	4.7	4.2	1.6	8.0	7.1	37.0	6.4	1.8	14.3	9.5	2.9	11.3	7.7	0.0	7.7	5.9	0.6	8.9	5.5	37.8	20.8	16.9	13.4	3.5	2.1	2.9	3.9	1.8	2.1	3.9	1.6	7.2	7.4	1.2	5.5	4.7	0.5	5.9	3.9	28.9	5.9	13.1	2.3	0.4	2.1	14.4	3.4	2.3	17.8	7.1	15.0	0.0	21.7	19.4	5.9	25.2	5.9	7.3	1.6	9.1	8.5	4.1	8.5	3.6	7.4	0.7	3.5	3.0	11.2	7.6	4.2	0.0	11.9	4.3	8.6	1.1	5.7	10.5	13.3	7.0	16.7	3.2	23.5	9.2	3.6	1.0	5.9	4.4	0.4	2.9	2.5	11.9	4.5	5.5	10.9	30.8	0.1	6.8	5.6	24.2	0.5	4.5	5.9	4.4	9.0	3.6	13.8	8.9	13.2	6.8	5.8	4.9	0.5	18.4	3.7	4.0	11.6	7.2	31.3	7.3	1.3	4.6	0.6	0.6	5.6	7.7	2.5	5.4	0.6	1.6	5.7	5.6	6.5	7.0	8.2	2.5	2.7	6.3	6.6	10.9	3.6	7.4	5.6	4.7	4.0	7.0	4.1	4.4	11.0	8.6	11.8	9.7	14.9	0.7	8.7	19.3	3.6	9.4	3.2	23.9	0.2	7.8	22.6
Cystathionine 1	1.5	2.9	7.2	4.0	5.2	1.5	13.4	6.1	9.1	4.8	2.8	7.7	10.3	4.5	4.1	3.5	0.7	5.7	8.3	0.2	14.0	9.2	9.3	7.0	10.9	9.1	4.7	3.0	2.5	2.5	5.3	1.6	3.3	2.8	2.4	10.8	5.5	8.4	2.1	2.6	4.2	1.3	8.7	4.6	7.0	2.8	2.0	2.7	8.0	5.9	1.8	5.2	2.2	7.6	2.0	7.5	7.7	3.1	9.3	3.5	2.8	3.9	5.3	4.4	1.8	4.4	2.4	4.6	2.1	1.4	3.7	9.2	10.4	11.4	1.8	3.5	2.0	2.9	1.5	3.5	5.0	5.5	5.6	4.2	2.4	5.6	2.2	1.2	1.6	1.6	3.6	3.2	1.3	1.9	2.7	3.2	2.2	5.3	4.8	4.3	3.1	7.2	6.5	0.4	4.0	3.4	1.8	4.8	9.4	5.7	4.2	6.6	4.2	5.3	1.8	4.0	5.6	6.3	6.5	6.3	5.1	11.8	2.1	0.9	1.6	1.8	3.5	2.2	3.6	0.8	3.6	0.9	2.9	3.9	5.5	1.7	6.9	3.8	1.2	3.7	2.7	3.6	5.2	2.8	3.0	4.9	2.9	2.0	3.9	1.6	2.0	6.7	20.1	8.2	5.8	6.1	4.4	3.3	7.7	1.7	1.5	2.4	10.8	7.3	5.7	10.4
Cystathionine 2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.4	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Lysine	57.2	137.0	96.9	60.1	74.9	19.3	94.1	162.5	1026.8	49.1	58.8	476.9	346.2	23.9	422.7	143.8	10.2	76.3	112.5	14.9	347.6	131.0	182.8	271.6	1043.2	140.5	35.4	39.0	74.0	38.0	78.5	35.8	26.7	17.1	41.7	280.1	111.8	91.2	139.2	82.4	111.4	20.2	622.4	133.3	259.0	138.4	29.5	48.3	289.3	193.0	7.6	1529.3	54.3	250.6	0.5	410.8	375.9	293.0	43.5	193.3	196.6	27.5	261.2	379.4	33.9	156.1	43.9	94.1	33.5	24.1	45.2	209.4	81.9	182.7	122.2	322.6	86.0	188.9	26.7	54.1	146.0	174.7	92.0	653.3	122.3	498.1	244.1	32.9	48.1	21.5	45.8	189.1	37.0	90.9	68.6	124.0	98.2	762.9	392.3	101.0	110.1	84.5	444.0	12.1	80.7	40.6	85.4	39.4	62.4	126.7	175.5	147.4	40.4	53.0	114.2	86.3	243.8	69.1	208.3	547.3	60.1	840.1	54.2	15.6	37.0	8.1	156.9	107.3	363.3	33.1	167.2	8.8	35.5	65.0	461.3	54.1	113.3	35.0	39.5	17.2	189.6	104.3	84.8	96.1	141.7	14.4	14.1	60.3	42.7	51.2	76.0	408.9	35.2	124.6	506.6	320.0	71.2	38.7	381.1	7.1	75.6	67.3	782.6	1.9	119.6	1097.2
Cystine	10.5	25.0	38.5	11.0	24.1	5.9	40.8	29.0	169.7	21.4	15.5	95.3	43.5	11.5	63.7	23.7	7.3	23.2	22.8	5.0	35.7	18.7	36.2	65.2	39.8	41.9	15.1	15.7	17.3	10.8	18.0	14.2	18.7	9.8	19.6	70.8	16.1	21.8	24.6	25.9	19.8	9.9	108.0	24.5	46.8	21.0	13.6	14.4	45.0	21.5	6.7	134.8	13.7	39.0	3.2	42.2	45.0	40.8	47.5	28.2	35.3	15.4	18.9	35.3	10.1	43.6	14.7	25.3	6.7	12.4	11.2	57.7	36.0	31.5	1.2	37.0	14.0	35.3	5.7	20.1	30.3	32.4	24.0	102.6	14.8	62.2	16.1	6.3	11.8	5.3	1.7	2.6	7.0	10.5	24.6	10.6	13.9	38.8	105.2	21.4	9.6	32.4	107.9	12.5	25.1	23.0	30.5	24.5	3.8	35.2	36.8	34.5	36.3	12.5	2.1	21.9	28.7	21.2	32.9	83.3	23.8	70.2	25.2	4.8	17.1	4.5	28.3	22.5	38.3	6.9	44.9	6.1	6.6	7.4	8.0	7.2	9.0	11.3	7.1	7.2	9.2	7.7	9.1	8.1	8.0	9.5	7.1	6.6	8.4	7.6	8.0	9.7	8.3	10.0	11.4	10.0	8.2	7.5	11.7	5.7	7.1	7.5	12.5	7.2	9.6	19.1
Tyrosine	28.7	107.8	2.2	82.0	52.6	37.4	85.1	96.7	190.5	42.6	15.8	76.6	118.9	16.8	56.2	27.5	20.3	51.0	69.7	13.2	102.9	53.4	93.5	202.0	160.5	99.9	39.2	40.8	39.6	40.3	28.6	28.0	35.0	12.1	58.8	181.5	37.1	19.9	19.4	72.7	81.8	24.6	71.9	85.3	216.9	61.1	28.1	55.5	97.1	76.5	21.9	170.3	49.7	248.5	6.7	151.8	90.7	60.9	94.8	81.2	50.4	9.2	22.6	28.6	35.6	44.6	49.2	67.8	0.3	32.2	16.5	154.6	67.3	38.4	3.3	77.0	26.8	86.3	18.8	44.5	62.8	60.1	53.6	98.7	31.6	79.9	36.1	24.7	31.7	14.6	17.4	15.8	16.5	37.9	73.2	26.4	49.9	109.3	111.5	30.5	26.8	79.6	41.3	20.7	28.2	37.4	27.6	65.1	25.6	108.3	137.0	52.5	2.3	24.8	33.2	3.6	72.6	69.5	83.4	71.5	34.8	142.3	65.0	34.0	33.0	7.6	11.1	130.1	107.1	18.5	40.8	17.0	16.8	41.2	2.7	62.5	53.3	38.6	18.1	19.0	22.7	30.4	90.7	28.4	65.0	41.8	11.3	40.3	44.1	49.5	45.0	120.3	64.0	100.7	12.7	88.7	41.4	23.8	129.9	21.0	53.9	29.3	265.1	5.0	88.7	111.9
Methionine	3.2	5.4	0.1	0.7	9.2	2.0	6.1	8.6	24.9	7.9	2.5	7.5	14.7	2.8	6.5	5.2	0.0	5.6	12.0	1.1	13.1	5.8	21.1	13.8	15.0	17.8	4.1	4.2	5.5	3.8	2.6	0.2	2.0	1.6	7.6	13.7	1.2	3.8	1.6	0.8	7.5	3.2	6.8	8.4	16.7	6.1	2.5	6.3	11.2	7.6	2.3	26.4	3.4	17.7	0.0	0.9	8.8	4.7	0.3	5.9	4.4	0.2	4.1	4.2	2.9	3.5	3.0	4.7	0.0	3.7	1.6	12.3	3.9	5.8	0.1	4.2	2.7	4.5	1.5	4.5	6.2	0.3	4.9	11.8	4.3	12.7	4.1	1.6	6.8	3.0	2.7	0.3	0.1	4.7	10.5	3.9	4.9	2.9	16.4	2.8	4.1	6.5	0.4	0.1	3.5	5.3	3.0	6.7	0.4	12.6	12.8	7.5	0.1	0.5	3.4	0.6	5.9	5.2	6.2	11.0	4.3	15.4	0.6	1.7	5.6	0.0	0.0	4.2	10.8	1.8	4.0	1.5	0.1	4.4	2.7	3.5	5.8	4.9	2.4	0.1	2.8	4.1	3.4	2.6	8.4	0.0	2.1	4.6	4.4	3.9	3.7	7.2	3.9	9.9	2.1	12.9	0.2	3.1	17.6	0.8	3.8	2.2	20.8	0.0	6.6	8.4
Valine	13.9	22.8	13.2	2.1	42.4	12.2	25.8	32.1	54.8	34.0	9.7	30.3	57.1	11.0	23.3	27.4	2.7	25.5	49.3	4.7	55.0	19.3	54.8	68.2	59.7	54.7	16.2	18.4	20.4	17.7	12.3	4.0	9.2	7.4	32.0	75.8	13.6	14.1	11.0	2.8	23.3	12.0	23.6	27.4	64.9	27.7	14.6	18.8	36.7	33.7	9.0	64.1	15.3	71.6	1.6	14.5	36.2	19.4	14.1	31.2	22.2	0.6	12.2	12.6	16.2	17.8	14.7	17.1	0.9	16.6	10.1	62.2	18.1	25.3	0.8	12.3	8.7	16.9	7.5	15.3	22.9	14.7	17.0	40.3	15.6	36.5	15.0	10.3	23.3	10.7	12.7	1.6	7.3	14.4	29.3	13.9	25.7	10.5	55.4	13.0	16.4	19.6	12.7	9.4	16.6	21.5	11.8	21.0	0.4	42.4	54.0	27.3	9.6	11.5	8.7	0.7	24.9	17.4	28.7	36.0	11.2	38.3	15.3	9.7	25.3	0.2	4.3	25.4	35.1	8.7	19.8	6.4	0.2	19.2	0.6	19.8	21.1	21.4	11.6	4.9	10.9	15.9	22.0	8.2	31.6	10.4	9.5	19.4	19.7	17.2	17.7	30.0	24.3	50.9	13.0	38.0	8.5	11.7	59.4	5.2	13.0	15.1	74.4	0.0	31.7	43.5
Isoleucine	4.5	7.4	0.1	0.3	11.3	2.9	7.6	9.2	18.1	8.4	2.8	8.4	16.5	2.7	6.0	5.4	0.7	6.8	17.1	1.0	12.3	1.7	18.7	23.6	17.8	16.5	4.8	5.6	6.1	6.5	3.3	0.0	1.7	2.0	11.7	22.7	3.1	4.6	2.4	2.3	8.1	3.7	5.8	9.4	17.7	9.0	3.7	6.7	13.2	10.9	2.8	21.6	4.2	19.6	0.0	7.8	13.4	5.2	4.9	10.1	7.5	0.0	4.0	3.8	4.5	5.3	4.6	6.3	0.5	7.3	2.7	18.1	6.0	9.4	0.0	0.1	2.8	3.1	2.5	7.4	8.7	7.2	5.2	14.0	5.4	12.8	5.2	3.1	7.3	3.2	2.8	0.4	0.1	4.8	11.5	4.4	9.5	7.9	20.1	1.0	4.4	7.1	1.3	2.5	5.6	3.4	4.6	7.5	3.6	14.0	18.5	9.2	0.9	4.2	2.7	0.2	7.4	6.7	8.3	10.5	0.2	14.4	0.4	2.7	8.6	0.0	0.7	8.6	11.9	3.2	6.6	1.9	4.7	6.5	1.5	7.9	7.3	6.2	3.7	0.2	3.9	5.3	4.7	2.9	10.2	0.0	2.8	6.9	7.9	7.1	6.7	10.5	3.8	15.2	2.4	11.9	0.0	3.4	19.3	0.4	2.7	3.5	23.9	0.0	9.8	9.8
allo-Isoleucine	0.0	0.1	0.6	0.6	0.4	0.0	0.5	0.5	0.8	0.9	0.0	0.3	0.7	0.0	0.7	1.0	0.1	0.1	0.3	0.0	1.6	0.3	1.4	1.1	0.5	1.2	0.2	0.3	0.3	0.2	0.1	0.1	0.1	0.0	2.2	0.9	0.1	0.0	0.1	0.2	0.6	0.0	0.3	0.1	0.4	0.2	0.0	0.1	0.7	0.3	0.0	1.0	0.4	0.8	0.0	1.0	1.5	0.5	0.4	0.5	0.3	0.1	0.0	0.0	0.5	0.1	0.6	1.1	0.1	3.8	0.2	1.0	0.7	0.4	0.2	0.4	0.2	0.6	0.2	0.5	0.8	0.8	0.4	1.0	0.4	1.2	0.5	0.3	0.0	0.2	0.3	0.3	0.5	0.5	1.3	0.4	0.9	0.6	3.0	0.6	0.4	0.3	0.4	0.7	0.3	0.2	0.4	0.2	0.3	1.3	1.0	0.6	0.2	0.2	0.5	0.0	0.2	0.4	0.6	0.4	0.1	1.8	1.3	0.0	0.3	0.0	0.0	0.2	1.0	0.0	0.1	0.0	0.2	0.2	0.1	0.4	0.5	0.7	0.0	0.1	0.0	0.2	1.2	0.0	0.3	0.4	0.0	0.1	0.3	0.0	0.4	0.3	1.2	0.8	1.0	0.8	0.1	0.3	0.6	0.3	0.0	0.0	1.5	0.0	0.6	1.7
Homocystine	0.0	0.0	0.1	0.2	0.0	0.0	0.1	0.1	0.3	0.1	0.0	0.4	0.1	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.5	0.2	0.3	0.4	0.5	0.2	0.0	0.0	0.0	0.0	0.1	0.0	0.1	0.0	0.0	0.2	0.2	0.1	0.0	0.0	0.0	0.0	0.3	0.1	0.0	0.2	0.0	0.0	0.3	0.1	0.0	0.7	0.1	0.0	0.0	0.2	0.1	0.1	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.1	0.0	0.0	0.0	0.2	0.2	0.2	0.0	0.1	0.0	0.1	0.0	0.1	0.1	0.3	0.1	0.3	0.1	0.3	0.0	0.1	0.0	0.1	0.0	0.0	0.1	0.1	0.0	0.1	0.0	0.0	0.5	0.1	0.0	0.0	0.2	0.0	0.1	0.0	0.0	0.0	0.0	0.1	0.0	0.1	0.0	0.1	0.0	0.1	0.0	0.0	0.0	0.4	0.0	0.2	0.1	0.0	0.1	0.0	0.0	0.1	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Leucine	8.7	21.3	5.2	0.5	24.5	7.7	20.2	24.1	58.1	20.0	6.8	23.2	39.5	5.9	23.4	19.3	0.3	17.7	38.5	2.9	37.3	13.6	58.2	57.1	47.6	47.8	12.1	14.5	16.0	14.2	9.1	0.1	6.5	5.5	24.0	50.3	10.5	11.7	8.2	1.2	23.2	9.3	21.5	21.7	40.4	21.9	10.3	16.4	32.4	27.7	7.3	70.1	11.9	45.2	0.0	7.6	42.5	14.1	5.0	24.6	20.0	0.1	12.2	12.1	12.7	14.5	11.8	19.2	0.2	16.5	8.0	45.0	16.3	22.3	0.1	15.4	8.5	13.6	6.1	19.3	23.6	3.4	14.4	37.1	15.3	36.6	16.9	7.8	19.3	7.2	7.6	0.7	1.5	12.8	27.7	12.8	24.3	11.3	64.4	7.3	6.0	20.9	6.0	2.7	12.6	13.0	9.8	18.0	0.3	39.5	44.7	23.0	0.9	11.2	4.6	0.5	22.7	17.7	25.0	36.3	2.2	48.4	6.8	7.8	17.0	0.0	0.0	22.3	33.8	6.1	15.4	5.0	0.0	15.4	0.3	13.5	18.7	15.4	8.5	0.2	11.1	14.3	17.7	8.4	28.2	2.4	7.7	15.6	12.9	14.6	16.0	24.9	12.9	37.7	5.7	35.1	3.5	7.6	51.6	1.7	8.1	10.0	57.9	0.1	25.1	32.7
Phenylalanine	17.7	49.8	31.6	32.7	35.0	15.7	41.0	36.8	87.5	28.7	9.9	30.7	67.4	11.1	25.4	44.5	8.8	25.1	56.6	5.6	65.7	23.3	68.8	96.8	71.5	69.1	19.1	20.9	21.5	23.3	14.7	18.9	18.9	6.3	37.0	87.5	15.3	18.2	13.5	26.3	44.1	15.3	30.1	39.5	100.9	34.3	14.4	28.0	62.8	42.9	12.9	88.4	22.3	127.9	3.9	45.1	40.5	27.5	31.9	35.9	24.2	11.9	14.6	16.0	20.9	23.6	21.6	29.3	7.6	20.1	8.9	80.1	35.3	36.8	4.3	29.6	15.3	48.0	11.4	29.5	34.4	25.3	27.6	73.7	18.6	48.4	20.7	12.3	27.4	9.9	11.8	8.5	12.5	16.2	49.9	14.1	23.2	41.5	69.9	20.8	20.0	38.3	27.7	19.6	21.4	30.5	17.9	38.5	6.6	68.8	84.5	36.4	17.5	11.8	20.7	12.9	39.2	30.0	43.1	52.8	28.9	77.2	40.4	15.9	26.2	3.9	13.3	61.9	43.9	14.2	24.1	10.3	4.4	17.2	16.0	28.7	23.5	21.4	11.8	11.7	13.8	22.0	43.3	13.8	38.6	19.7	8.4	22.1	28.6	25.3	17.4	36.2	39.1	46.8	41.2	56.3	21.3	14.9	73.9	14.1	26.0	14.7	95.6	0.1	36.9	84.8
Tryptophan	18.9	78.7	44.3	62.9	52.7	26.3	60.5	69.9	165.8	22.3	12.1	59.4	90.2	10.8	38.5	72.6	16.7	36.4	61.9	9.6	83.7	21.1	75.5	156.0	111.2	85.9	24.9	25.6	26.0	28.7	22.3	33.6	31.6	7.6	45.9	115.9	24.3	16.0	13.9	48.1	59.6	17.9	50.6	50.3	170.8	48.9	18.3	32.3	74.7	54.4	16.7	159.6	26.1	187.2	6.3	97.3	88.3	37.9	52.7	56.3	32.0	22.5	19.2	16.0	29.5	35.7	28.0	43.7	17.1	25.0	11.1	100.8	50.6	32.6	14.0	64.9	21.5	56.5	13.6	34.9	66.2	36.7	31.6	102.2	25.1	46.8	27.3	13.0	30.0	10.1	11.2	21.7	26.9	29.4	85.0	16.5	32.3	47.2	86.9	29.2	16.8	65.7	43.3	31.5	19.9	48.7	20.1	62.0	18.8	90.7	105.1	37.5	30.5	18.0	23.9	28.8	49.8	58.3	59.2	54.3	53.5	77.3	60.0	21.4	34.5	10.3	18.7	96.6	78.1	13.6	35.8	11.9	12.7	13.6	35.3	45.6	31.0	15.6	11.7	13.6	13.0	23.6	56.4	19.5	45.8	28.4	5.4	25.5	37.1	57.5	29.2	76.6	42.8	80.8	85.8	70.1	29.7	16.3	106.8	17.5	43.9	27.3	173.3	0.0	61.8	172.7
MS_METABOLITE_DATA_END
#METABOLITES
METABOLITES_START
metabolite_name
Histidine
Hydroxyproline
1-Methylhistidine
3-Methylhistidine
Asparagine
Phosphoethanolamine
Arginine
Carnosine
Taurine
Anserine
Serine
Glutamine
Ethanolamine
Glycine
Aspartic Acid
Sarcosine
Citrulline
Glutamic Acid
beta-Alanine
Threonine
Alanine
gamma-Amino-N-butyric-acid
alpha-Aminoadipic-acid
beta-Aminoisobutyric-acid
Proline
Hydroxylysine 1
Hydroxylysine 2
alpha-Amino-N-butyric-acid
Ornithine
Cystathionine 1
Cystathionine 2
Lysine
Cystine
Tyrosine
Methionine
Valine
Isoleucine
allo-Isoleucine
Homocystine
Leucine
Phenylalanine
Tryptophan
METABOLITES_END
#END