#METABOLOMICS WORKBENCH hormel101_20170623_122525 DATATRACK_ID:1089 STUDY_ID:ST000640 ANALYSIS_ID:AN000972 PROJECT_ID:PR000458
VERSION             	1
CREATED_ON             	June 25, 2017, 4:49 pm
#PROJECT
PR:PROJECT_TITLE                 	Biomarkers of diabetes risk in children: role of obesity and exercise
PR:PROJECT_SUMMARY               	This proposal addresses a gap in knowledge about biomarkers for insulin
PR:PROJECT_SUMMARY               	resistance and diabetes. It remains unclear why some populations develop
PR:PROJECT_SUMMARY               	diabetes at higher rates than others and whether prevention and treatment
PR:PROJECT_SUMMARY               	strategies should also differ. The main goal of the current study is to
PR:PROJECT_SUMMARY               	determine the impact of body composition and physical activity on biomarkers for
PR:PROJECT_SUMMARY               	insulin resistance in American Indian adolescents. We propose to use a targeted
PR:PROJECT_SUMMARY               	metabolomic approach to measure amino compounds and fatty acids in plasma. We
PR:PROJECT_SUMMARY               	will address these goals by exploring two Specific Aims: 1. To determine the
PR:PROJECT_SUMMARY               	effects of obesity and physical activity on circulating biomarkers for diabetes
PR:PROJECT_SUMMARY               	and metabolic disease risk in American Indian youth. Plasma samples used for
PR:PROJECT_SUMMARY               	measurements of amino compounds and fatty acids will be acquired from boys and
PR:PROJECT_SUMMARY               	girls 11-21 years old classified as, a) obese, low habitual physical activity
PR:PROJECT_SUMMARY               	and low fitness; b) normal weight, low habitual physical activity and low
PR:PROJECT_SUMMARY               	fitness; or, c) normal weight, high habitual physical activity and high fitness.
PR:PROJECT_SUMMARY               	2. To determine the impact of exercise training on circulating biomarkers for
PR:PROJECT_SUMMARY               	diabetes and metabolic disease risk in obese American Indian youth. The same
PR:PROJECT_SUMMARY               	obese group tested in the cross-sectional comparison in Aim 1 will complete 16
PR:PROJECT_SUMMARY               	weeks of aerobic exercise training. Plasma samples acquired before and after
PR:PROJECT_SUMMARY               	training will be used to measure amino compounds and fatty acids. The results of
PR:PROJECT_SUMMARY               	this project will provide novel information about the metabolic changes
PR:PROJECT_SUMMARY               	associated with insulin resistance, obesity, and physical activity in young
PR:PROJECT_SUMMARY               	people who are at risk for, but have not yet developed cardiometabolic disease.
PR:PROJECT_SUMMARY               	The study design takes advantage of, and supports the scientific partnership
PR:PROJECT_SUMMARY               	among investigators at the University of Oklahoma Health Sciences Center,
PR:PROJECT_SUMMARY               	Choctaw Nation of Oklahoma, and Mayo Clinic Rochester. This will set the stage
PR:PROJECT_SUMMARY               	for future lifestyle intervention studies to further explore the concepts
PR:PROJECT_SUMMARY               	outlined in this proposal.
PR:INSTITUTE                     	Mayo Clinic
PR:LAST_NAME                     	Short
PR:FIRST_NAME                    	Kevin
PR:ADDRESS                       	University of Oklahoma Health Sciences Center 1200 Children’s Ave, Suite 4500
PR:ADDRESS                       	Oklahoma City, OK 73104
PR:EMAIL                         	kevin-short@ouhsc.edu
PR:PHONE                         	405-271-8001
#STUDY
ST:STUDY_TITLE                   	Targeted NEFA in American Indian Adolescents (part I)
ST:STUDY_SUMMARY                 	The goal of this study is to determine the effect of physical activity on the
ST:STUDY_SUMMARY                 	blood concentrations of several compounds that are proposed to be markers of
ST:STUDY_SUMMARY                 	diabetic risk. We will compare results from normal weight and obese American
ST:STUDY_SUMMARY                 	Indian adolescents, with high or low habitual physical activity. We will also
ST:STUDY_SUMMARY                 	compare the same blood markers in the obese group before and after 4 months of
ST:STUDY_SUMMARY                 	exercise to measure the benefit of the program.
ST:INSTITUTE                     	Mayo Clinic
ST:LAST_NAME                     	Short
ST:FIRST_NAME                    	Kevin
ST:ADDRESS                       	University of Oklahoma Health Sciences Center 1200 Children’s Ave, Suite 4500
ST:ADDRESS                       	Oklahoma City, OK 73104
ST:EMAIL                         	kevin-short@ouhsc.edu
ST:PHONE                         	405-271-8001
#SUBJECT
SU:SUBJECT_TYPE                  	Human
SU:SUBJECT_SPECIES               	Homo sapiens
SU:TAXONOMY_ID                   	9606
#SUBJECT_SAMPLE_FACTORS:         	SUBJECT(optional)[tab]SAMPLE[tab]FACTORS(NAME:VALUE pairs separated by |)[tab]Additional sample data
SUBJECT_SAMPLE_FACTORS           	434-001	1	Date of Study:7/24/2013 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=F
SUBJECT_SAMPLE_FACTORS           	434-001	2	Date of Study:11/26/13 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=F
SUBJECT_SAMPLE_FACTORS           	434-002	3	Date of Study:7/31/2013 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=F
SUBJECT_SAMPLE_FACTORS           	434-002	4	Date of Study:11/25/13 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=F
SUBJECT_SAMPLE_FACTORS           	434-004	7	Date of Study:8/16/2013 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	434-004	8	Date of Study:12/23/13 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	434-005	9	Date of Study:9/27/2013 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	434-005	10	Date of Study:1/31/14 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	434-006	11	Date of Study:10/2/2013 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=F
SUBJECT_SAMPLE_FACTORS           	434-006	12	Date of Study:1/31/14 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=F
SUBJECT_SAMPLE_FACTORS           	434-007	13	Date of Study:10/4/2013 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	434-007	14	Date of Study:2/7/14 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	434-008	15	Date of Study:10/11/2013 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=F
SUBJECT_SAMPLE_FACTORS           	434-008	16	Date of Study:3/17/14 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=F
SUBJECT_SAMPLE_FACTORS           	434-009	17	Date of Study:10/2/2013 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	434-010	19	Date of Study:9/27/2013 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=F
SUBJECT_SAMPLE_FACTORS           	434-010	20	Date of Study:2/21/14 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=F
SUBJECT_SAMPLE_FACTORS           	434-011	21	Date of Study:10/25/2013 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=F
SUBJECT_SAMPLE_FACTORS           	434-011	22	Date of Study:3/17/14 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=F
SUBJECT_SAMPLE_FACTORS           	434-013	23	Date of Study:12/23/2014 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=F
SUBJECT_SAMPLE_FACTORS           	434-013	24	Date of Study:4/28/14 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=F
SUBJECT_SAMPLE_FACTORS           	434-014	25	Date of Study:3/14/2014 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	434-015	27	Date of Study:5/16/2014 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=F
SUBJECT_SAMPLE_FACTORS           	434-015	28	Date of Study:9/5/14 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=F
SUBJECT_SAMPLE_FACTORS           	434-016	29	Date of Study:7/18/2014 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=F
SUBJECT_SAMPLE_FACTORS           	434-016	30	Date of Study:11/25/14 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=F
SUBJECT_SAMPLE_FACTORS           	434-017	31	Date of Study:10/30/2014 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=F
SUBJECT_SAMPLE_FACTORS           	434-018	33	Date of Study:12/12/2014 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=F
SUBJECT_SAMPLE_FACTORS           	434-018	34	Date of Study:5/8/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=F
SUBJECT_SAMPLE_FACTORS           	434-019	35	Date of Study:2/20/2015 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=F
SUBJECT_SAMPLE_FACTORS           	434-019	36	Date of Study:7/20/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=F
SUBJECT_SAMPLE_FACTORS           	434-020	37	Date of Study:2/20/2015 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=F
SUBJECT_SAMPLE_FACTORS           	434-020	38	Date of Study:7/20/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=F
SUBJECT_SAMPLE_FACTORS           	434-021	39	Date of Study:3/13/2015 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	434-021	40	Date of Study:7/21/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	434-022	41	Date of Study:3/13/2015 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	434-022	42	Date of Study:7/21/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	434-023	43	Date of Study:3/27/2015 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=F
SUBJECT_SAMPLE_FACTORS           	434-023	44	Date of Study:8/7/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=F
SUBJECT_SAMPLE_FACTORS           	434-024	45	Date of Study:3/27/2015 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	434-024	46	Date of Study:8/4/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	434-025	47	Date of Study:3/27/2015 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	434-025	48	Date of Study:8/4/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	434-026	49	Date of Study:3/16/2015 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	434-026	50	Date of Study:8/11/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	434-027	51	Date of Study:3/16/2015 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	434-027	52	Date of Study:8/11/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	434-028	53	Date of Study:5/5/2015 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=F
SUBJECT_SAMPLE_FACTORS           	434-029	55	Date of Study:5/22/2015 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	434-029	56	Date of Study:9/25/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	434-030	57	Date of Study:6/11/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	434-030	58	Date of Study:10/28/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	434-031	59	Date of Study:7/14/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	434-031	60	Date of Study:11/6/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	434-032	61	Date of Study:7/14/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=F
SUBJECT_SAMPLE_FACTORS           	434-032	62	Date of Study:11/6/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=F
SUBJECT_SAMPLE_FACTORS           	434-033	63	Date of Study:6/30/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=F
SUBJECT_SAMPLE_FACTORS           	434-033	64	Date of Study:11/23/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=F
SUBJECT_SAMPLE_FACTORS           	434-034	65	Date of Study:6/30/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=F
SUBJECT_SAMPLE_FACTORS           	434-034	66	Date of Study:11/17/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=F
SUBJECT_SAMPLE_FACTORS           	434-038	67	Date of Study:8/17/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	434-038	68	Date of Study:2/9/16 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	434-039	69	Date of Study:8/28/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	434-039	70	Date of Study:2/9/16 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	434-040	71	Date of Study:9/1/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	434-042	73	Date of Study:10/23/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	434-042	74	Date of Study:3/4/16 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	434-044	75	Date of Study:12/18/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=F
SUBJECT_SAMPLE_FACTORS           	434-045	77	Date of Study:12/18/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	434-047	79	Date of Study:2/8/16 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=F
SUBJECT_SAMPLE_FACTORS           	434-048	81	Date of Study:2/8/16 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	434-101	83	Date of Study:8/29/14 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	434-101	84	Date of Study:12/16/14 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	434-102	85	Date of Study:9/18/2014 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=F
SUBJECT_SAMPLE_FACTORS           	434-102	86	Date of Study:1/20/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=F
SUBJECT_SAMPLE_FACTORS           	434-106	87	Date of Study:10/10/14 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=F
SUBJECT_SAMPLE_FACTORS           	434-106	88	Date of Study:3/4/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=F
SUBJECT_SAMPLE_FACTORS           	434-107	89	Date of Study:11/28/2014 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=F
SUBJECT_SAMPLE_FACTORS           	434-107	90	Date of Study:5/8/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=F
SUBJECT_SAMPLE_FACTORS           	434-110	91	Date of Study:12/4/2014 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	434-110	92	Date of Study:4/10/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	434-111	93	Date of Study:12/11/14 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	434-111	94	Date of Study:4/30/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	434-112	95	Date of Study:1/5/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=F
SUBJECT_SAMPLE_FACTORS           	434-112	96	Date of Study:5/8/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=F
SUBJECT_SAMPLE_FACTORS           	434-113	97	Date of Study:1/5/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=F
SUBJECT_SAMPLE_FACTORS           	434-113	98	Date of Study:5/8/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=F
SUBJECT_SAMPLE_FACTORS           	434-115	99	Date of Study:2/13/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=F
SUBJECT_SAMPLE_FACTORS           	434-118	101	Date of Study:6/8/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	434-118	102	Date of Study:10/5/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	434-120	103	Date of Study:8/4/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	434-120	104	Date of Study:12/29/16 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	434-121	105	Date of Study:8/5/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	434-121	106	Date of Study:12/11/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	434-123	107	Date of Study:8/18/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=F
SUBJECT_SAMPLE_FACTORS           	434-123	108	Date of Study:1/15/16 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=F
SUBJECT_SAMPLE_FACTORS           	434-125	109	Date of Study:8/21/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	434-128	111	Date of Study:12/8/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	434-130	113	Date of Study:12/29/16 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=F
SUBJECT_SAMPLE_FACTORS           	434-131	115	Date of Study:12/29/16 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=F
SUBJECT_SAMPLE_FACTORS           	434-132	117	Date of Study:1/5/16 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	434-301	119	Date of Study:8/4/15 | Time:baseline | Study Group:normal weight reference group adolescents	Sex=M
SUBJECT_SAMPLE_FACTORS           	434-302	121	Date of Study:8/4/15 | Time:baseline | Study Group:normal weight reference group adolescents	Sex=M
SUBJECT_SAMPLE_FACTORS           	434-303	123	Date of Study:10/19/15 | Time:baseline | Study Group:normal weight reference group adolescents	Sex=M
SUBJECT_SAMPLE_FACTORS           	434-304	125	Date of Study:10/15/15 | Time:baseline | Study Group:normal weight reference group adolescents	Sex=F
SUBJECT_SAMPLE_FACTORS           	434-305	127	Date of Study:12/17/15 | Time:baseline | Study Group:normal weight reference group adolescents	Sex=M
SUBJECT_SAMPLE_FACTORS           	434-306	129	Date of Study:12/17/15 | Time:baseline | Study Group:normal weight reference group adolescents	Sex=F
SUBJECT_SAMPLE_FACTORS           	434-307	131	Date of Study:12/23/15 | Time:baseline | Study Group:normal weight reference group adolescents	Sex=F
SUBJECT_SAMPLE_FACTORS           	434-308	133	Date of Study:1/9/16 | Time:baseline | Study Group:normal weight reference group adolescents	Sex=M
SUBJECT_SAMPLE_FACTORS           	11333	135	Date of Study:6/8/2010 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	11333	136	Date of Study:7/15/10 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	11097	137	Date of Study:5/25/2010 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	11097	138	Date of Study:6/25/10 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	11327	139	Date of Study:6/1/2010 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	11327	140	Date of Study:7/14/10 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	11326	141	Date of Study:6/2/2010 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	11326	142	Date of Study:7/14/10 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	11313	143	Date of Study:6/23/2010 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program	Sex=F
SUBJECT_SAMPLE_FACTORS           	11313	144	Date of Study:8/5/10 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program	Sex=F
SUBJECT_SAMPLE_FACTORS           	11314	145	Date of Study:6/23/2010 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program	Sex=F
SUBJECT_SAMPLE_FACTORS           	11314	146	Date of Study:8/5/10 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program	Sex=F
SUBJECT_SAMPLE_FACTORS           	11537	147	Date of Study:8/10/2010 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program	Sex=F
SUBJECT_SAMPLE_FACTORS           	11537	148	Date of Study:9/29/10 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program	Sex=F
SUBJECT_SAMPLE_FACTORS           	11547	149	Date of Study:8/30/2010 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	11547	150	Date of Study:9/30/2010 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	11580	151	Date of Study:12/8/10 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program	Sex=F
SUBJECT_SAMPLE_FACTORS           	11580	152	Date of Study:2/15/2011 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program	Sex=F
SUBJECT_SAMPLE_FACTORS           	11588	153	Date of Study:1/6/11 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program	Sex=F
SUBJECT_SAMPLE_FACTORS           	11588	154	Date of Study:2/14/2011 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program	Sex=F
SUBJECT_SAMPLE_FACTORS           	11620	155	Date of Study:2/18/11 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	11620	156	Date of Study:4/22/2011 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	11638	157	Date of Study:5/20/2011 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	11638	158	Date of Study:7/7/11 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	11635	159	Date of Study:5/3/2011 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program	Sex=F
SUBJECT_SAMPLE_FACTORS           	11635	160	Date of Study:6/8/11 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program	Sex=F
SUBJECT_SAMPLE_FACTORS           	11636	161	Date of Study:5/3/2011 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	11636	162	Date of Study:6/8/2011 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	11637	163	Date of Study:5/26/11 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	11637	164	Date of Study:8/5/2011 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	11644	165	Date of Study:7/13/11 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	11644	166	Date of Study:8/25/2011 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	11675	167	Date of Study:6/23/11 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	11675	168	Date of Study:8/10/2011 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	11685	169	Date of Study:7/27/11 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	11685	170	Date of Study:9/6/2011 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	11681	171	Date of Study:7/19/11 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	11681	172	Date of Study:8/24/2011 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	11683	173	Date of Study:7/20/11 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	11683	174	Date of Study:8/24/2011 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	11684	175	Date of Study:7/18/11 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	11684	176	Date of Study:8/17/2011 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program	Sex=M
SUBJECT_SAMPLE_FACTORS           	11517	177	Date of Study:7/1/10 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program	Sex=F
SUBJECT_SAMPLE_FACTORS           	11517	178	Date of Study:8/6/2010 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program	Sex=F
#COLLECTION
CO:COLLECTION_SUMMARY            	Male and female American Indians 11-21 years old are being recruited from the
CO:COLLECTION_SUMMARY            	Choctaw Nation Health Service Area of southeast Oklahoma. We use a collaborative
CO:COLLECTION_SUMMARY            	approach as recently described by our American Indian Programs Coordinator (12).
CO:COLLECTION_SUMMARY            	The primary characteristics of the three study groups are shown in Table 1.
CO:COLLECTION_SUMMARY            	Group 1 is obese (Body mass index, BMI, ≥95th percentile for age- and
CO:COLLECTION_SUMMARY            	sex-specific norms based on growth charts from the Centers for Disease Control),
CO:COLLECTION_SUMMARY            	with pubertal maturation level ≥Tanner Stage 2, family history of T2D, and
CO:COLLECTION_SUMMARY            	recent history of low physical activity. Low physical activity, defined as
CO:COLLECTION_SUMMARY            	attaining <30 minutes of structured moderate-to-vigorous intensity exercise on 3
CO:COLLECTION_SUMMARY            	days/week over the preceding 3 months, is confirmed through questionnaires and
CO:COLLECTION_SUMMARY            	use of an accelerometer. Groups 2 and 3 are both classified as normal weight
CO:COLLECTION_SUMMARY            	(BMI greater than 20th and less than 85th percentile) with maturation level
CO:COLLECTION_SUMMARY            	≥Tanner Stage 2. Group 2 will have low physical activity (same as Group 1),
CO:COLLECTION_SUMMARY            	while Group 3 will have high physical activity, defined as >30 minutes of
CO:COLLECTION_SUMMARY            	structured moderate-to-vigorous intensity exercise on >3 days/week in the
CO:COLLECTION_SUMMARY            	preceding 3 months. Additional eligibility criteria are: lack of diabetes or
CO:COLLECTION_SUMMARY            	other potentially confounding metabolic disorders, able to safely exercise,
CO:COLLECTION_SUMMARY            	willingness to complete the testing and participation schedule, and not on
CO:COLLECTION_SUMMARY            	medications known to impact the stated outcomes. A medical history and physical
CO:COLLECTION_SUMMARY            	exam is performed to assure suitability for the study during the initial
CO:COLLECTION_SUMMARY            	screening.
#TREATMENT
TR:TREATMENT_SUMMARY             	Only Group 1 participants continue on to the exercise training program, which
TR:TREATMENT_SUMMARY             	lasts 48 weeks. Follow-up measurements of the clinical and functional tests are
TR:TREATMENT_SUMMARY             	performed at 16, 32, and 48 weeks; values at 16 weeks will be used for the
TR:TREATMENT_SUMMARY             	current proposal to assure adequate sample size. Exercise sessions are performed
TR:TREATMENT_SUMMARY             	at the Choctaw Wellness Centers, where fitness professionals provide instruction
TR:TREATMENT_SUMMARY             	and supervision. Participants receive incentives for completing 20-60 minutes of
TR:TREATMENT_SUMMARY             	moderate-to-vigorous physical activity (MVPA) on 3 days per week. MVPA is
TR:TREATMENT_SUMMARY             	defined as exercise that elicits a heart rate ≥ 70% of peak heart rate.
TR:TREATMENT_SUMMARY             	Several types of exercise can be selected, including walking, running, cycling,
TR:TREATMENT_SUMMARY             	aerobic dance or other activities. To promote healthy behavior within the
TR:TREATMENT_SUMMARY             	community and foster social support, all participants are invited to exercise
TR:TREATMENT_SUMMARY             	with family members or friends if they choose. Exercise intensity is monitored
TR:TREATMENT_SUMMARY             	by recording heart rate with a chest strap transmitter that outputs to a
TR:TREATMENT_SUMMARY             	computer for quantification and data storage. Training sessions are also
TR:TREATMENT_SUMMARY             	recorded in an exercise log by each participant and confirmed by fitness center
TR:TREATMENT_SUMMARY             	staff.
#SAMPLEPREP
SP:SAMPLEPREP_SUMMARY            	Part 1: Longer-term exercise training study: Samples #1-133. Overweight/Obese
SP:SAMPLEPREP_SUMMARY            	adolescents (IDs 434-001 through 434-132) enrolled into a 48-week exercise
SP:SAMPLEPREP_SUMMARY            	program (3 days per week). Samples submitted are from the pre-training
SP:SAMPLEPREP_SUMMARY            	(Baseline) and the end of the first 16 weeks (Post-training) times. Compliance
SP:SAMPLEPREP_SUMMARY            	with the exercise program varies widely among participants. An additional set of
SP:SAMPLEPREP_SUMMARY            	normal weight reference group adolescents (IDs 434-301 through 434-308) are
SP:SAMPLEPREP_SUMMARY            	included. Note that 15 OW/OB participants in the exercise group and all 8 NW
SP:SAMPLEPREP_SUMMARY            	reference group participants have only a single baseline sample. All samples
SP:SAMPLEPREP_SUMMARY            	were collected following overnight fast into EDTA (lavender top) glass tubes for
SP:SAMPLEPREP_SUMMARY            	preparation of plasma, kept on ice 20 minutes, spun, aliquoted and then kept
SP:SAMPLEPREP_SUMMARY            	frozen. None have been previously used. Part 2: Short-term exercise training
SP:SAMPLEPREP_SUMMARY            	study: Samples with ID 11xxx. Overweight/Obese adolescents completed a
SP:SAMPLEPREP_SUMMARY            	short-term exercise program, consisting of 10 sessions over 5 weeks. Samples
SP:SAMPLEPREP_SUMMARY            	were collected following overnight fast, before (Baseline) and after
SP:SAMPLEPREP_SUMMARY            	(Post-training) the training program. These samples are serum since plasma was
SP:SAMPLEPREP_SUMMARY            	used for other analyses. All tubes are marked with a unique ID number (shown in
SP:SAMPLEPREP_SUMMARY            	list below) in black marker. Additional sample details on the labels are listed
SP:SAMPLEPREP_SUMMARY            	in the accompanying Excel spreadsheet.
#CHROMATOGRAPHY
CH:CHROMATOGRAPHY_TYPE           	Reversed phase
CH:INSTRUMENT_NAME               	Agilent 1290 Infinity
CH:COLUMN_NAME                   	Waters Acquity BEH C18 (150 x 2.1mm, 1.7um)
#ANALYSIS
AN:ANALYSIS_TYPE                 	MS
#MS
MS:INSTRUMENT_NAME               	Agilent 6460 QQQ
MS:INSTRUMENT_TYPE               	Triple quadrupole
MS:MS_TYPE                       	ESI
MS:ION_MODE                      	NEGATIVE
#MS_METABOLITE_DATA
MS_METABOLITE_DATA:UNITS         	uM
MS_METABOLITE_DATA_START
Samples	1	2	3	4	7	8	9	10	11	12	13	14	15	16	17	19	20	21	22	23	24	25	27	28	29	30	31	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	53	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	73	74	75	77	79	81	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	101	102	103	104	105	106	107	108	109	111	113	115	117	119	121	123	125	127	129	131	133	135	136	137	138	139	140	141	142	143	144	145	146	147	148	149	150	151	152	153	154	155	156	157	158	159	160	161	162	163	164	165	166	167	168	169	170	171	172	173	174	175	176	177	178
Factors	Date of Study:7/24/2013 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:11/26/13 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:7/31/2013 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:11/25/13 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:8/16/2013 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:12/23/13 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:9/27/2013 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:1/31/14 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:10/2/2013 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:1/31/14 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:10/4/2013 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:2/7/14 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:10/11/2013 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:3/17/14 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:10/2/2013 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:9/27/2013 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:2/21/14 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:10/25/2013 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:3/17/14 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:12/23/2014 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:4/28/14 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:3/14/2014 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:5/16/2014 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:9/5/14 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:7/18/2014 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:11/25/14 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:10/30/2014 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:12/12/2014 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:5/8/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:2/20/2015 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:7/20/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:2/20/2015 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:7/20/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:3/13/2015 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:7/21/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:3/13/2015 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:7/21/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:3/27/2015 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:8/7/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:3/27/2015 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:8/4/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:3/27/2015 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:8/4/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:3/16/2015 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:8/11/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:3/16/2015 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:8/11/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:5/5/2015 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:5/22/2015 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:9/25/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:6/11/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:10/28/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:7/14/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:11/6/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:7/14/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:11/6/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:6/30/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:11/23/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:6/30/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:11/17/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:8/17/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:2/9/16 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:8/28/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:2/9/16 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:9/1/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:10/23/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:3/4/16 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:12/18/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:12/18/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:2/8/16 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:2/8/16 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:8/29/14 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:12/16/14 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:9/18/2014 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:1/20/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:10/10/14 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:3/4/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:11/28/2014 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:5/8/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:12/4/2014 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:4/10/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:12/11/14 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:4/30/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:1/5/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:5/8/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:1/5/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:5/8/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:2/13/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:6/8/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:10/5/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:8/4/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:12/29/16 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:8/5/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:12/11/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:8/18/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:1/15/16 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:8/21/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:12/8/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:12/29/16 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:12/29/16 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:1/5/16 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program	Date of Study:8/4/15 | Time:baseline | Study Group:normal weight reference group adolescents	Date of Study:8/4/15 | Time:baseline | Study Group:normal weight reference group adolescents	Date of Study:10/19/15 | Time:baseline | Study Group:normal weight reference group adolescents	Date of Study:10/15/15 | Time:baseline | Study Group:normal weight reference group adolescents	Date of Study:12/17/15 | Time:baseline | Study Group:normal weight reference group adolescents	Date of Study:12/17/15 | Time:baseline | Study Group:normal weight reference group adolescents	Date of Study:12/23/15 | Time:baseline | Study Group:normal weight reference group adolescents	Date of Study:1/9/16 | Time:baseline | Study Group:normal weight reference group adolescents	Date of Study:6/8/2010 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program	Date of Study:7/15/10 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program	Date of Study:5/25/2010 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program	Date of Study:6/25/10 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program	Date of Study:6/1/2010 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program	Date of Study:7/14/10 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program	Date of Study:6/2/2010 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program	Date of Study:7/14/10 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program	Date of Study:6/23/2010 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program	Date of Study:8/5/10 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program	Date of Study:6/23/2010 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program	Date of Study:8/5/10 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program	Date of Study:8/10/2010 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program	Date of Study:9/29/10 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program	Date of Study:8/30/2010 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program	Date of Study:9/30/2010 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program	Date of Study:12/8/10 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program	Date of Study:2/15/2011 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program	Date of Study:1/6/11 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program	Date of Study:2/14/2011 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program	Date of Study:2/18/11 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program	Date of Study:4/22/2011 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program	Date of Study:5/20/2011 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program	Date of Study:7/7/11 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program	Date of Study:5/3/2011 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program	Date of Study:6/8/11 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program	Date of Study:5/3/2011 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program	Date of Study:6/8/2011 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program	Date of Study:5/26/11 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program	Date of Study:8/5/2011 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program	Date of Study:7/13/11 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program	Date of Study:8/25/2011 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program	Date of Study:6/23/11 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program	Date of Study:8/10/2011 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program	Date of Study:7/27/11 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program	Date of Study:9/6/2011 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program	Date of Study:7/19/11 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program	Date of Study:8/24/2011 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program	Date of Study:7/20/11 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program	Date of Study:8/24/2011 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program	Date of Study:7/18/11 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program	Date of Study:8/17/2011 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program	Date of Study:7/1/10 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program	Date of Study:8/6/2010 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program
EPA	0.933950063	1.164219584	1.173683625	2.092721169	1.631062769	3.012672659	1.698679173	2.40875098	2.531547377	2.434227924	1.913765893	1.228552958	1.445146701	3.700809237	1.943034856	1.512747795	2.486815404	2.202751742	1.987091079	1.283629469	1.370345908	1.173639998	1.905017448	1.06635379	1.5452791	1.47151987	2.686142271	0.924594685	1.269364314	1.28070856	1.470978051	1.814294701	1.644380436	2.793846338	4.421402152	1.096828748	2.110715563	1.501905157	1.952372987	3.750077219	6.061520568	2.527762552	1.488366362	2.065752369	1.719090048	9.244945959	9.905636999	2.361703367	2.295658377	1.870867778	2.011900352	3.211111956	1.811305365	1.845314769	1.01566859	0.602328699	1.640187505	0.997911689	2.174654196	1.276107056	1.806099559	1.32786672	3.408504816	1.632441341	2.895861031	1.125974137	0.962867248	2.519680878	1.950618766	1.018227523	0.537784831	1.358828853	1.243592373	1.347773477	0.904364888	1.374408512	0.904912525	1.144432085	1.344752584	1.178361667	1.358955758	0.862500362	0.569986275	1.535860543	1.957800282	1.17933367	1.246972807	0.792708514	1.455095954	1.249100756	2.36530634	1.358075167	1.823011001	0.614631916	2.493339716	1.391377576	1.922070874	0.943313979	2.361384167	2.171572189	1.770443147	3.336098432	3.558816194	1.159209856	5.829943045	0.493507846	0.980092582	2.238717634	0.913898388	3.154687722	3.764819423	2.872003928	1.077312179	1.508362681	1.620043759	2.596293614	2.015036368	1.672433318	1.87178534	1.0371372	1.33296338	1.13788655	1.083738356	3.617619535	9.27573648	1.58745811	9.51830962	7.385802843	1.699491875	2.887711429	2.650949828	0.837737332	0.900902702	2.895590542	1.262811796	1.706107582	1.377039366	1.120741879	1.623106475	1.181296796	0.977562009	1.196151191	1.246562792	5.058074256	5.221843376	2.940732033	1.90157345	3.246603702	3.562060505	0.953616332	37.57067774	4.73468513	3.494117164
linolenic	9.383295606	5.172455377	6.148660281	3.269035054	10.64260409	14.53291793	10.3697851	11.21287342	15.17756596	12.63566211	14.26069214	8.951828383	15.7335161	13.04630393	20.35470947	16.68238424	20.75490945	14.70119418	6.263014219	9.078028926	8.804134414	6.267325207	4.076733213	3.779963748	16.65533482	13.31308525	17.84592867	12.7016537	5.619429378	7.936991434	8.264539358	9.328969705	10.33568982	19.24834777	17.27623949	13.23298944	14.1899139	8.990726434	11.39384457	14.9591503	8.704157737	34.3196204	6.763146172	8.898998772	5.081107967	19.83930465	11.93855431	17.97175748	13.50651472	26.99359286	14.99052265	22.09483309	5.286603272	12.26036633	10.54892404	6.648420646	10.0163398	8.273654857	14.07946082	9.837139008	24.2905518	17.83394871	20.41717892	14.6808523	11.02436071	7.054668174	5.875056088	14.05694371	7.582549273	8.057063774	4.785486426	12.87034103	10.46968971	10.71182723	9.215622654	9.302165441	7.963574802	8.989885203	11.94237506	9.763130393	9.781314567	9.696259047	8.039095396	13.51254242	16.0748959	11.20193642	16.08178859	11.00672756	16.98867869	30.85409709	14.84884518	14.98202764	3.724281326	6.695965022	10.98771294	6.378863371	15.81805986	7.209666511	21.84637857	19.59045402	13.15752224	14.55845714	7.593488285	6.544071624	36.02677643	2.446632117	7.632976086	40.10564665	11.86851263	22.12043272	14.02099075	16.59601932	13.72358652	20.74657551	10.5659986	13.15286624	16.50208936	22.99741591	17.79014544	14.42402978	15.22666859	15.47030565	7.463229591	12.43316658	25.81754305	17.31836821	8.404725367	25.0728555	10.38501916	12.635464	11.74546932	13.56607901	20.14523997	21.11107227	7.575902326	12.08934675	6.188181079	7.378200857	11.36939265	13.16368322	8.298408999	15.45755999	13.6432701	12.14059107	11.17445877	18.60508715	24.5769514	22.92963832	23.46762749	18.82812102	13.95047352	38.65259716	27.26478924
DHA	6.142948873	6.175073565	4.704231605	6.25733619	6.999308553	11.12971285	13.25045253	18.51685565	15.5063686	13.09851985	10.74520646	10.21149609	9.711528221	13.12855819	11.38725909	10.24170988	14.32786083	12.42383926	11.07087287	8.022631807	6.707419304	7.597091932	8.512504752	4.010156764	10.18208741	10.09008382	19.35125257	8.295125299	6.626157002	6.597112743	8.682113279	5.359990283	5.340210305	7.118472885	8.976586421	6.059795866	7.843735025	4.972356318	7.101762082	7.826983746	7.485747729	17.32905449	8.72860848	13.97321991	7.728948799	17.20470788	12.99881331	11.6747514	6.988305409	6.69174064	9.309030752	12.67572903	6.87505642	9.377903534	6.070169653	3.367240336	8.61604494	6.260387776	11.88507972	7.629266871	9.072154277	9.340248157	12.80882491	9.446746197	11.4940748	6.310717688	5.537100016	10.95949361	10.29527356	6.884991837	3.29574872	10.90237753	8.348049166	7.56432959	7.872188943	10.44481662	6.128708702	9.020921083	8.195343132	11.97648405	10.5370919	7.284630585	3.968677724	11.5115202	12.22194483	10.30701355	6.249617783	7.451578415	7.954831809	11.09628256	11.61854814	10.4072044	5.988254274	6.3773188	7.50134572	5.573215352	12.98444753	9.309882907	10.50676357	14.61857032	11.88344925	20.3143541	15.32744523	5.654572628	19.86113145	5.350266814	10.32194372	17.39662653	12.1248076	15.42992048	14.52553856	14.77964418	8.403475676	10.16008118	8.452741377	12.18467327	8.81291164	10.48331625	10.02061905	8.921867651	9.594563486	7.898414585	4.668428963	5.711044861	14.67637248	11.04635701	8.006027108	15.78982351	6.240956681	7.139518003	10.10541577	5.607124521	4.338336501	19.98994785	9.771720115	7.286330894	6.507890497	6.083875601	5.905541369	6.610550458	5.845720838	8.320556766	6.351979906	16.77738646	19.93381111	18.33741566	11.20005339	17.32306158	15.59966667	7.512676437	5.571772981	17.13351691	15.30625441
myristic	7.227192245	3.38267714	3.624475155	2.78873229	6.806190751	11.2511489	7.059874571	7.744985488	14.66157775	10.4733055	12.04505296	9.387254276	9.692493841	9.47261878	13.4162145	10.93472471	17.64940487	11.65569268	5.418988728	5.308483259	5.37495206	5.289375996	6.075986754	3.965011951	7.690587695	8.022676891	10.06993526	6.797516893	3.294314526	4.108071103	3.964428039	4.057882788	3.961477472	11.94905015	11.85713954	7.3063859	11.25636652	3.87765344	4.354500295	10.95969549	6.986158442	8.838871613	3.327524178	6.68348179	5.303141852	13.44475266	9.111648972	10.26305599	3.208474959	6.4262026	9.526019328	12.93278846	5.330036518	7.823480791	6.584890445	4.211517552	7.776714492	5.103078574	6.994796764	3.880152689	12.45372687	8.97226462	12.03128074	9.068967649	6.182131625	4.401180977	3.362726961	11.73246813	6.439765071	5.836421294	3.233818423	7.604391372	5.536608046	7.704424774	5.05529067	8.494970172	7.764670711	6.627237361	7.307129973	7.403588122	4.733565657	8.155993146	3.938645275	11.42370394	12.65472299	6.181695083	11.5127796	8.095663181	15.08324149	13.12181479	8.346617226	8.89329357	4.432025653	2.421599031	8.163761203	4.126854596	7.279501376	5.512383347	16.07934571	16.5673825	7.641706456	9.011547544	6.61783319	4.837190907	29.74006502	1.885042514	10.03679598	19.90308132	11.93619452	10.15938945	13.17596886	11.5369815	7.987955163	8.939885606	7.799983091	9.65440852	12.24172964	18.81469047	13.98455905	13.24309218	12.01256014	12.71126655	5.050872133	11.62256229	16.27379708	9.57243252	6.140341852	23.09269822	8.687775548	13.89937969	11.73524095	6.861746167	6.750112299	19.94821256	13.12973973	9.323427413	7.170795	9.029986268	13.37120138	6.758669382	7.897142501	9.446091829	7.360172527	13.24327713	14.65658913	10.2293479	15.17339149	17.8119417	18.29466743	10.55665066	7.253943769	29.08766036	19.4264834
palmitoleic	17.35876318	10.41546102	6.397536573	3.763679655	16.69748133	29.08421505	17.08036711	16.57881243	37.61695908	32.89047155	28.14247504	19.27061056	32.71157491	25.59247564	43.58560072	28.8458614	44.81517727	44.05023177	21.38303116	6.992613267	8.982451719	15.96356213	8.197110538	6.991653011	25.9113405	25.14867324	24.08125254	20.9603564	9.622720021	13.31780673	11.49726114	13.47335699	13.46927429	29.1577995	26.49138863	21.58520659	26.26515612	8.847890286	8.129917529	37.49801313	19.90006846	19.95190878	9.063053236	16.10469065	11.41275877	41.02840246	31.22077316	19.03608723	8.230333878	26.52920464	24.52195224	35.28232267	9.607670059	17.79913437	14.59707215	10.28313879	13.41553359	12.52902434	24.08189742	12.07707748	24.74175961	19.50337502	24.19207277	18.25760253	14.08951131	13.42655398	8.853103122	23.16755642	12.53505367	15.30572204	6.502513637	19.39041021	9.054142728	22.14018378	16.18129869	19.35757536	13.07353866	12.71842007	14.79246741	16.08669752	8.289077451	18.76662925	6.044579817	23.39618044	32.43161912	11.219478	28.8245233	15.09177836	41.88724454	37.63477923	19.94383499	21.6823911	5.865491681	4.568512818	25.83550439	11.45124323	24.63747031	14.01631568	30.85094402	34.63050383	20.34102023	11.04258239	5.594962502	9.972404773	83.00571108	3.060680433	14.36792919	29.69065801	19.73064609	19.15917593	28.41275499	13.15134412	8.773566172	8.95418269	10.35615848	18.9157275	27.75744746	32.45706178	29.11837554	38.46372768	34.44063334	18.02974087	6.17534437	22.88238705	55.68320365	21.15548119	15.93747296	60.73168975	20.31084679	29.89123249	25.10049219	13.62023453	9.194321871	50.65047119	17.53823773	16.02558043	8.931033117	10.59070959	20.75904442	14.22851047	16.86589963	18.67616864	14.09627589	34.30882731	39.77564823	19.36732448	36.03672632	32.45080749	41.13165192	18.92792391	14.11156302	74.5554406	48.55673696
arachidonic	2.36078479	2.466864481	2.003841957	2.782012796	3.044232709	4.966864701	2.457910608	4.370917494	5.197470115	4.812176417	4.38865262	3.898450533	2.616069078	6.036425005	4.712429896	3.311019171	4.29731843	5.525572173	6.276060272	3.361446092	3.508457151	3.422933992	4.011193492	2.186600732	3.214981749	2.846198989	6.094337607	2.637092176	2.857143634	3.183361461	4.094725426	2.703655541	3.045322491	4.038900656	5.744627497	2.643094783	3.990556217	2.167676033	2.806214518	4.318489627	3.395538862	6.945578417	3.238201834	5.595910817	4.189097277	6.24193031	5.376399983	4.608573379	3.52939387	3.524212849	5.300379074	7.067577235	3.774811914	4.586812513	2.99037534	1.693177701	3.848641251	2.519592636	5.596482025	2.417402111	3.85620945	3.570969804	5.93875195	4.546848475	5.050955552	3.898845159	3.191455595	5.106059965	5.626513269	3.343258122	1.382066453	3.388766303	3.49264282	3.138612429	2.484263941	3.815626403	1.794289073	2.546505164	3.149191128	3.490894803	3.345805417	2.010732932	1.26503596	2.725642788	3.138048801	3.495909697	2.490281954	2.55393893	3.492979176	3.751193388	5.4616818	2.992839618	2.734581152	1.533711383	5.121802843	2.317095971	4.845011649	2.343844567	5.184595151	5.106160386	4.061913691	7.578709918	6.078341766	2.916332001	11.3966743	1.255879416	3.33621133	5.956403447	3.406711558	7.536021479	9.393901737	11.30121375	4.086530259	7.489501257	7.79716134	8.713673513	9.669298419	6.462040896	8.845540297	4.538333881	5.60211158	5.954474964	2.499828784	2.152630043	5.688281501	3.880372293	3.330816707	6.751515881	3.368045527	5.168884203	6.916388932	3.457557677	5.022300716	7.549507029	4.543402164	4.63924384	3.784055946	3.573208249	3.943405813	4.095949289	2.740569956	4.542340745	4.568213025	7.219062137	6.784085976	5.853659943	10.02727654	3.822745192	4.991710487	4.974322922	4.507624241	9.856109349	8.552363942
palmiteladic	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
linoleic	83.99298953	54.57373411	46.04445983	24.66120452	82.4425574	103.5885044	79.12510765	83.01509797	136.376601	124.0977102	134.9802715	97.49415415	123.7822519	105.4304138	166.0143001	117.8707895	157.5146633	134.5514276	78.13996901	62.64200969	64.3749325	66.60538974	39.57553963	33.73234506	114.3617464	94.51165194	135.2916754	103.4249639	51.38026714	62.74841221	62.42134915	69.95140734	72.22457339	127.7218582	118.8899771	94.83904403	108.5455401	58.85148419	71.84445062	142.6068215	84.01188427	171.5966417	53.51224639	95.62461073	49.06568481	157.1645433	105.3998596	150.4375691	86.30195153	189.7825289	133.6328354	169.0680072	45.64831053	88.21397839	78.47795057	52.19202405	65.17258768	63.45227801	104.184541	68.66275384	141.2119441	124.1885353	160.6254806	136.2691059	78.67151817	71.13223263	61.72218444	107.4082911	62.2414394	78.24251814	41.97756557	106.5702383	77.52941026	93.94160152	75.08810554	84.05719953	61.27706167	78.97792669	96.37496634	78.51624687	62.03403103	83.46298391	55.2174563	108.5919467	137.1340209	82.26309064	114.9839767	102.2284734	132.0119947	189.4941567	127.9605155	108.4620516	35.01793595	43.52882665	88.69251027	48.26808608	115.2533562	59.50150814	167.1191568	142.5362356	96.48114174	80.71692871	45.34745927	58.83872411	240.5498288	29.21288137	72.23473571	219.3921134	102.7286568	151.222683	148.2833697	133.044817	101.8022679	94.25486639	84.68402395	108.6567151	140.6651397	193.701135	159.1146725	163.0072719	177.1257937	127.9543285	54.30002623	79.42577168	199.4489118	125.825367	68.09899042	172.0698931	73.20368055	124.8863855	111.661445	120.0816948	151.393801	166.2668176	54.5153214	97.52595787	51.93632012	59.36853485	100.8846422	88.01345967	63.94710869	121.8698833	96.56906565	126.4524384	123.4816884	122.2539941	191.8714021	137.1103485	165.7584294	183.0547352	118.8571286	245.2951827	179.8657414
palmitic	115.8729025	71.67874837	54.22545046	36.74492661	119.028218	155.6755644	127.2069945	143.5375483	205.6010276	191.5403532	192.0283023	149.0859683	149.9743616	139.4187745	239.8141541	160.992302	218.4607604	171.2862364	109.3957811	77.83309831	72.22139161	97.82409796	67.97632236	47.38097424	129.5380951	127.8720256	173.8379706	131.6749425	68.89073439	75.75812821	73.573122	78.00525607	76.85859074	160.7079096	180.4166605	115.2605305	168.7305511	53.3136027	66.39593539	184.526154	116.492082	164.5572359	77.88125886	121.216367	88.16144471	224.1621145	181.1803735	184.4654556	91.8565823	192.5113346	142.1683418	191.380653	84.87660809	113.5316831	96.08476522	62.19840663	90.62919405	88.21178109	127.3908817	98.11473663	172.756203	154.430549	193.9028299	148.0980335	141.4982976	86.57951801	69.3129549	159.0752222	102.5180289	106.7269201	61.32232801	120.5944852	89.26608987	116.7617152	84.01697032	143.505501	95.30879103	104.1577638	112.2542449	105.1308905	75.78764886	145.2208386	73.01425338	145.6008609	202.9946954	102.8247043	143.9959011	133.8159912	203.5301146	211.4162648	116.6316887	124.2445254	55.25050775	49.45159122	148.7942107	78.28317961	136.8738177	74.40169969	212.0016516	195.0860273	124.3159843	96.4071214	73.39397044	78.94851729	304.6568344	36.3836171	102.5426304	217.9492643	147.8706293	150.2178965	187.0033898	132.3038047	95.67424103	111.9877974	102.5615332	132.4750602	146.75321	193.4363346	168.8422142	174.3646098	182.5456598	186.7654281	64.45146888	123.6377076	237.2542097	144.6322746	92.70500974	245.8212712	105.3193896	184.6041851	154.6804915	105.1872431	118.2651361	238.7576533	125.9537552	122.3332177	82.49822685	99.1033858	163.0775125	88.11275481	81.07556997	184.1235	129.009084	154.0561364	169.9313006	140.8023649	212.9446317	199.9942824	228.7435602	192.4975309	141.8101683	283.0469303	216.4473041
oleic	150.8677426	104.2739786	66.45210995	39.03036076	144.7382228	194.3250232	153.5660029	162.5251497	283.9138153	271.3166293	252.3956527	193.4358591	224.299321	190.7698587	335.5284817	211.2074692	299.2193358	281.7528245	172.6498038	82.14220685	92.20251264	131.8277649	77.67398558	60.41847601	212.6430179	188.89274	248.09423	171.8870927	83.06719994	121.4714283	114.9281624	117.9624294	115.6147111	220.8772034	214.2463676	160.6308408	216.1764738	65.70176341	78.1239858	282.7096274	168.5898595	195.5274854	90.90669138	188.2174496	104.677257	307.4251126	251.7262078	251.6451271	93.65543859	241.2811131	212.6830947	261.5595162	92.2413705	143.2931854	118.4048707	79.81203682	101.1643498	107.8458657	189.80588	125.8629394	197.6579264	203.9329716	273.7809036	203.0639297	159.9211133	126.2478767	95.38888013	209.0022824	135.6676186	138.2130153	75.11349372	191.6034888	120.8055434	170.8035047	107.9607692	201.6015265	115.1737773	138.7165709	153.4218607	157.5071922	98.31106104	193.7397432	80.87275229	188.763266	266.5220366	132.1420257	199.7499354	181.081875	293.9208875	273.7742062	165.6594386	194.790408	59.25419763	64.25433527	181.6981607	109.2889136	195.0355732	112.1378902	305.2705546	256.1247848	184.840357	118.8457987	71.5851368	108.3846613	523.6693957	44.32510273	135.7652869	324.0444252	201.3155717	206.811583	280.1024986	178.6849848	123.1858114	144.3654285	141.0215955	173.525617	226.5966415	285.8229754	254.6641004	282.9473105	260.7857897	220.4278125	76.49730288	165.4623374	380.9773727	192.1620275	127.835469	329.8040102	140.6654306	266.282526	214.2670141	147.6544532	161.0860959	316.564564	106.0739604	175.3754957	100.9132752	121.0493433	227.9745952	121.1207638	121.1942949	228.6746784	185.1686138	244.287799	295.601072	206.464475	326.159832	256.8206965	304.4023428	248.2154594	201.7070012	459.6972284	328.5764215
elaidic	10.75664214	6.10449024	5.388344085	8.166821536	10.52695158	13.55769909	10.51890338	10.56291403	21.63661748	17.32900949	16.33306311	14.17445169	15.78051681	12.54432187	22.47352744	17.23997523	24.04613074	16.11380659	9.869372336	7.706354957	7.770707474	9.473771653	7.283161063	4.486546385	12.12642254	13.01770455	15.71460915	10.83888273	5.80502441	6.741691036	5.836062092	8.389999622	6.458053439	19.27709596	16.78939026	11.90147292	14.90264645	4.300014347	5.880855517	19.92348234	11.10756218	12.75867875	5.977892184	13.53666343	8.477867138	22.50752975	18.86900992	18.15401015	5.092183235	18.70165117	10.28789556	15.37415624	10.14866969	11.74885064	8.572670058	5.564234047	7.726639811	5.375278979	7.834850409	6.728334603	14.01943671	12.08442432	16.79800069	12.48134282	9.222929683	6.391948248	4.485152785	15.18595197	9.747553662	14.65942761	13.25939215	13.23168612	7.197742727	9.610554954	9.925996772	14.48859378	10.31761647	10.94149022	11.27400512	14.00815971	6.992366749	22.74439947	5.520306492	12.08588798	18.00940348	9.515366899	10.70020021	12.48109338	14.30668996	409.1305426	10.83585141	9.455082967	5.144011981	6.938413659	10.92415268	5.591859743	10.09161106	7.298168223	26.45749967	22.76411769	12.58133739	10.27752935	10.25114544	10.45841788	41.26918659	2.564027698	9.634844148	34.0618962	11.61557349	49.31179582	22.81002257	22.9704298	12.70937238	17.49205857	12.13987888	19.90629997	17.67051001	29.27749376	25.36482818	23.75618436	21.05686522	20.0855596	8.366094512	14.83028798	21.88018231	17.04873395	16.06577218	28.79620319	12.06833679	19.13503774	15.33421966	14.48249429	13.52941566	27.59551873	12.00195581	13.50940804	11.5318888	14.86539274	20.81737522	9.014645042	9.542085308	32.55662991	13.90262081	18.07028484	15.84776943	18.17739441	22.36252936	20.22026158	24.43483903	18.35677992	20.92311153	40.14606996	29.51439576
stearic	30.44708366	19.79638087	21.14114137	16.48949292	30.44252927	44.13583375	33.70960709	43.68585335	48.46892237	37.12492444	45.45341514	38.67505682	33.51848049	35.31259478	41.66082282	38.6796011	42.38712104	31.74669844	21.12795142	28.77233322	26.51467515	27.37411561	21.42106269	15.18618254	34.51785918	38.53071218	46.06070262	39.22087722	24.53512471	28.95346136	23.82412443	23.13477629	21.94996348	45.21782125	52.32878	32.96167395	46.59974726	19.1994153	22.98726499	39.66909121	34.22065978	48.90999636	22.81893429	48.10936923	32.94449265	50.81098562	45.29432208	53.77027852	28.66623191	41.96132719	37.92930343	44.15266566	32.86274833	36.05016076	27.24282263	17.00465992	29.72048887	29.44579893	29.23431529	30.86192898	48.0606999	48.65994487	51.83779797	45.62372306	38.37651354	21.37375086	26.43685229	42.09714781	33.19318941	40.49818682	28.04930202	38.21666645	35.41775121	30.99633565	22.25863093	48.0602646	25.04501346	31.95745668	33.13147443	34.80822254	27.99930486	40.92803955	25.967663	37.00291381	51.83816951	31.47000536	23.16043426	40.1562459	43.66134213	58.10103581	35.62165889	37.01879693	18.63130107	27.31899732	34.86730814	28.57283105	39.96739195	24.44631243	54.68149483	50.90484187	32.77583942	38.61696741	31.84342823	30.10176118	56.03575478	12.34930382	35.05997104	67.9916401	44.20843193	52.86524679	46.91911944	52.14159891	39.97681978	45.30512225	32.87895435	40.91466794	36.69616538	44.25356053	45.16938063	41.50059708	40.99954917	54.62021204	24.73003507	30.83082152	47.39020071	35.79921079	25.50668541	44.13469344	25.23767046	43.5160625	38.79323895	37.54354452	49.70253202	45.98836119	33.37565029	44.7413837	34.70461066	35.2695823	43.11894094	30.13682544	20.22839633	61.72155708	46.45320575	37.37964052	48.20958673	42.46594091	49.15352867	48.30056815	49.56364576	49.01633895	46.59974341	49.45185998	53.06151449
MS_METABOLITE_DATA_END
#METABOLITES
METABOLITES_START
metabolite_name
EPA
linolenic
DHA
myristic
palmitoleic
arachidonic
palmiteladic
linoleic
palmitic
oleic
elaidic
stearic
METABOLITES_END
#END