#METABOLOMICS WORKBENCH hormel101_20170623_122525 DATATRACK_ID:1089 STUDY_ID:ST000640 ANALYSIS_ID:AN000972 PROJECT_ID:PR000458 VERSION 1 CREATED_ON June 25, 2017, 4:49 pm #PROJECT PR:PROJECT_TITLE Biomarkers of diabetes risk in children: role of obesity and exercise PR:PROJECT_SUMMARY This proposal addresses a gap in knowledge about biomarkers for insulin PR:PROJECT_SUMMARY resistance and diabetes. It remains unclear why some populations develop PR:PROJECT_SUMMARY diabetes at higher rates than others and whether prevention and treatment PR:PROJECT_SUMMARY strategies should also differ. The main goal of the current study is to PR:PROJECT_SUMMARY determine the impact of body composition and physical activity on biomarkers for PR:PROJECT_SUMMARY insulin resistance in American Indian adolescents. We propose to use a targeted PR:PROJECT_SUMMARY metabolomic approach to measure amino compounds and fatty acids in plasma. We PR:PROJECT_SUMMARY will address these goals by exploring two Specific Aims: 1. To determine the PR:PROJECT_SUMMARY effects of obesity and physical activity on circulating biomarkers for diabetes PR:PROJECT_SUMMARY and metabolic disease risk in American Indian youth. Plasma samples used for PR:PROJECT_SUMMARY measurements of amino compounds and fatty acids will be acquired from boys and PR:PROJECT_SUMMARY girls 11-21 years old classified as, a) obese, low habitual physical activity PR:PROJECT_SUMMARY and low fitness; b) normal weight, low habitual physical activity and low PR:PROJECT_SUMMARY fitness; or, c) normal weight, high habitual physical activity and high fitness. PR:PROJECT_SUMMARY 2. To determine the impact of exercise training on circulating biomarkers for PR:PROJECT_SUMMARY diabetes and metabolic disease risk in obese American Indian youth. The same PR:PROJECT_SUMMARY obese group tested in the cross-sectional comparison in Aim 1 will complete 16 PR:PROJECT_SUMMARY weeks of aerobic exercise training. Plasma samples acquired before and after PR:PROJECT_SUMMARY training will be used to measure amino compounds and fatty acids. The results of PR:PROJECT_SUMMARY this project will provide novel information about the metabolic changes PR:PROJECT_SUMMARY associated with insulin resistance, obesity, and physical activity in young PR:PROJECT_SUMMARY people who are at risk for, but have not yet developed cardiometabolic disease. PR:PROJECT_SUMMARY The study design takes advantage of, and supports the scientific partnership PR:PROJECT_SUMMARY among investigators at the University of Oklahoma Health Sciences Center, PR:PROJECT_SUMMARY Choctaw Nation of Oklahoma, and Mayo Clinic Rochester. This will set the stage PR:PROJECT_SUMMARY for future lifestyle intervention studies to further explore the concepts PR:PROJECT_SUMMARY outlined in this proposal. PR:INSTITUTE Mayo Clinic PR:LAST_NAME Short PR:FIRST_NAME Kevin PR:ADDRESS University of Oklahoma Health Sciences Center 1200 Children’s Ave, Suite 4500 PR:ADDRESS Oklahoma City, OK 73104 PR:EMAIL kevin-short@ouhsc.edu PR:PHONE 405-271-8001 #STUDY ST:STUDY_TITLE Targeted NEFA in American Indian Adolescents (part I) ST:STUDY_SUMMARY The goal of this study is to determine the effect of physical activity on the ST:STUDY_SUMMARY blood concentrations of several compounds that are proposed to be markers of ST:STUDY_SUMMARY diabetic risk. We will compare results from normal weight and obese American ST:STUDY_SUMMARY Indian adolescents, with high or low habitual physical activity. We will also ST:STUDY_SUMMARY compare the same blood markers in the obese group before and after 4 months of ST:STUDY_SUMMARY exercise to measure the benefit of the program. ST:INSTITUTE Mayo Clinic ST:LAST_NAME Short ST:FIRST_NAME Kevin ST:ADDRESS University of Oklahoma Health Sciences Center 1200 Children’s Ave, Suite 4500 ST:ADDRESS Oklahoma City, OK 73104 ST:EMAIL kevin-short@ouhsc.edu ST:PHONE 405-271-8001 #SUBJECT SU:SUBJECT_TYPE Human SU:SUBJECT_SPECIES Homo sapiens SU:TAXONOMY_ID 9606 #SUBJECT_SAMPLE_FACTORS: SUBJECT(optional)[tab]SAMPLE[tab]FACTORS(NAME:VALUE pairs separated by |)[tab]Additional sample data SUBJECT_SAMPLE_FACTORS 434-001 1 Date of Study:7/24/2013 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=F SUBJECT_SAMPLE_FACTORS 434-001 2 Date of Study:11/26/13 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=F SUBJECT_SAMPLE_FACTORS 434-002 3 Date of Study:7/31/2013 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=F SUBJECT_SAMPLE_FACTORS 434-002 4 Date of Study:11/25/13 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=F SUBJECT_SAMPLE_FACTORS 434-004 7 Date of Study:8/16/2013 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=M SUBJECT_SAMPLE_FACTORS 434-004 8 Date of Study:12/23/13 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=M SUBJECT_SAMPLE_FACTORS 434-005 9 Date of Study:9/27/2013 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=M SUBJECT_SAMPLE_FACTORS 434-005 10 Date of Study:1/31/14 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=M SUBJECT_SAMPLE_FACTORS 434-006 11 Date of Study:10/2/2013 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=F SUBJECT_SAMPLE_FACTORS 434-006 12 Date of Study:1/31/14 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=F SUBJECT_SAMPLE_FACTORS 434-007 13 Date of Study:10/4/2013 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=M SUBJECT_SAMPLE_FACTORS 434-007 14 Date of Study:2/7/14 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=M SUBJECT_SAMPLE_FACTORS 434-008 15 Date of Study:10/11/2013 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=F SUBJECT_SAMPLE_FACTORS 434-008 16 Date of Study:3/17/14 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=F SUBJECT_SAMPLE_FACTORS 434-009 17 Date of Study:10/2/2013 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=M SUBJECT_SAMPLE_FACTORS 434-010 19 Date of Study:9/27/2013 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=F SUBJECT_SAMPLE_FACTORS 434-010 20 Date of Study:2/21/14 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=F SUBJECT_SAMPLE_FACTORS 434-011 21 Date of Study:10/25/2013 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=F SUBJECT_SAMPLE_FACTORS 434-011 22 Date of Study:3/17/14 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=F SUBJECT_SAMPLE_FACTORS 434-013 23 Date of Study:12/23/2014 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=F SUBJECT_SAMPLE_FACTORS 434-013 24 Date of Study:4/28/14 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=F SUBJECT_SAMPLE_FACTORS 434-014 25 Date of Study:3/14/2014 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=M SUBJECT_SAMPLE_FACTORS 434-015 27 Date of Study:5/16/2014 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=F SUBJECT_SAMPLE_FACTORS 434-015 28 Date of Study:9/5/14 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=F SUBJECT_SAMPLE_FACTORS 434-016 29 Date of Study:7/18/2014 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=F SUBJECT_SAMPLE_FACTORS 434-016 30 Date of Study:11/25/14 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=F SUBJECT_SAMPLE_FACTORS 434-017 31 Date of Study:10/30/2014 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=F SUBJECT_SAMPLE_FACTORS 434-018 33 Date of Study:12/12/2014 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=F SUBJECT_SAMPLE_FACTORS 434-018 34 Date of Study:5/8/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=F SUBJECT_SAMPLE_FACTORS 434-019 35 Date of Study:2/20/2015 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=F SUBJECT_SAMPLE_FACTORS 434-019 36 Date of Study:7/20/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=F SUBJECT_SAMPLE_FACTORS 434-020 37 Date of Study:2/20/2015 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=F SUBJECT_SAMPLE_FACTORS 434-020 38 Date of Study:7/20/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=F SUBJECT_SAMPLE_FACTORS 434-021 39 Date of Study:3/13/2015 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=M SUBJECT_SAMPLE_FACTORS 434-021 40 Date of Study:7/21/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=M SUBJECT_SAMPLE_FACTORS 434-022 41 Date of Study:3/13/2015 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=M SUBJECT_SAMPLE_FACTORS 434-022 42 Date of Study:7/21/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=M SUBJECT_SAMPLE_FACTORS 434-023 43 Date of Study:3/27/2015 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=F SUBJECT_SAMPLE_FACTORS 434-023 44 Date of Study:8/7/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=F SUBJECT_SAMPLE_FACTORS 434-024 45 Date of Study:3/27/2015 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=M SUBJECT_SAMPLE_FACTORS 434-024 46 Date of Study:8/4/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=M SUBJECT_SAMPLE_FACTORS 434-025 47 Date of Study:3/27/2015 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=M SUBJECT_SAMPLE_FACTORS 434-025 48 Date of Study:8/4/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=M SUBJECT_SAMPLE_FACTORS 434-026 49 Date of Study:3/16/2015 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=M SUBJECT_SAMPLE_FACTORS 434-026 50 Date of Study:8/11/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=M SUBJECT_SAMPLE_FACTORS 434-027 51 Date of Study:3/16/2015 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=M SUBJECT_SAMPLE_FACTORS 434-027 52 Date of Study:8/11/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=M SUBJECT_SAMPLE_FACTORS 434-028 53 Date of Study:5/5/2015 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=F SUBJECT_SAMPLE_FACTORS 434-029 55 Date of Study:5/22/2015 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=M SUBJECT_SAMPLE_FACTORS 434-029 56 Date of Study:9/25/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=M SUBJECT_SAMPLE_FACTORS 434-030 57 Date of Study:6/11/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=M SUBJECT_SAMPLE_FACTORS 434-030 58 Date of Study:10/28/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=M SUBJECT_SAMPLE_FACTORS 434-031 59 Date of Study:7/14/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=M SUBJECT_SAMPLE_FACTORS 434-031 60 Date of Study:11/6/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=M SUBJECT_SAMPLE_FACTORS 434-032 61 Date of Study:7/14/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=F SUBJECT_SAMPLE_FACTORS 434-032 62 Date of Study:11/6/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=F SUBJECT_SAMPLE_FACTORS 434-033 63 Date of Study:6/30/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=F SUBJECT_SAMPLE_FACTORS 434-033 64 Date of Study:11/23/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=F SUBJECT_SAMPLE_FACTORS 434-034 65 Date of Study:6/30/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=F SUBJECT_SAMPLE_FACTORS 434-034 66 Date of Study:11/17/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=F SUBJECT_SAMPLE_FACTORS 434-038 67 Date of Study:8/17/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=M SUBJECT_SAMPLE_FACTORS 434-038 68 Date of Study:2/9/16 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=M SUBJECT_SAMPLE_FACTORS 434-039 69 Date of Study:8/28/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=M SUBJECT_SAMPLE_FACTORS 434-039 70 Date of Study:2/9/16 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=M SUBJECT_SAMPLE_FACTORS 434-040 71 Date of Study:9/1/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=M SUBJECT_SAMPLE_FACTORS 434-042 73 Date of Study:10/23/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=M SUBJECT_SAMPLE_FACTORS 434-042 74 Date of Study:3/4/16 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=M SUBJECT_SAMPLE_FACTORS 434-044 75 Date of Study:12/18/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=F SUBJECT_SAMPLE_FACTORS 434-045 77 Date of Study:12/18/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=M SUBJECT_SAMPLE_FACTORS 434-047 79 Date of Study:2/8/16 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=F SUBJECT_SAMPLE_FACTORS 434-048 81 Date of Study:2/8/16 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=M SUBJECT_SAMPLE_FACTORS 434-101 83 Date of Study:8/29/14 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=M SUBJECT_SAMPLE_FACTORS 434-101 84 Date of Study:12/16/14 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=M SUBJECT_SAMPLE_FACTORS 434-102 85 Date of Study:9/18/2014 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=F SUBJECT_SAMPLE_FACTORS 434-102 86 Date of Study:1/20/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=F SUBJECT_SAMPLE_FACTORS 434-106 87 Date of Study:10/10/14 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=F SUBJECT_SAMPLE_FACTORS 434-106 88 Date of Study:3/4/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=F SUBJECT_SAMPLE_FACTORS 434-107 89 Date of Study:11/28/2014 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=F SUBJECT_SAMPLE_FACTORS 434-107 90 Date of Study:5/8/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=F SUBJECT_SAMPLE_FACTORS 434-110 91 Date of Study:12/4/2014 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=M SUBJECT_SAMPLE_FACTORS 434-110 92 Date of Study:4/10/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=M SUBJECT_SAMPLE_FACTORS 434-111 93 Date of Study:12/11/14 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=M SUBJECT_SAMPLE_FACTORS 434-111 94 Date of Study:4/30/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=M SUBJECT_SAMPLE_FACTORS 434-112 95 Date of Study:1/5/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=F SUBJECT_SAMPLE_FACTORS 434-112 96 Date of Study:5/8/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=F SUBJECT_SAMPLE_FACTORS 434-113 97 Date of Study:1/5/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=F SUBJECT_SAMPLE_FACTORS 434-113 98 Date of Study:5/8/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=F SUBJECT_SAMPLE_FACTORS 434-115 99 Date of Study:2/13/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=F SUBJECT_SAMPLE_FACTORS 434-118 101 Date of Study:6/8/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=M SUBJECT_SAMPLE_FACTORS 434-118 102 Date of Study:10/5/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=M SUBJECT_SAMPLE_FACTORS 434-120 103 Date of Study:8/4/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=M SUBJECT_SAMPLE_FACTORS 434-120 104 Date of Study:12/29/16 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=M SUBJECT_SAMPLE_FACTORS 434-121 105 Date of Study:8/5/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=M SUBJECT_SAMPLE_FACTORS 434-121 106 Date of Study:12/11/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=M SUBJECT_SAMPLE_FACTORS 434-123 107 Date of Study:8/18/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=F SUBJECT_SAMPLE_FACTORS 434-123 108 Date of Study:1/15/16 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=F SUBJECT_SAMPLE_FACTORS 434-125 109 Date of Study:8/21/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=M SUBJECT_SAMPLE_FACTORS 434-128 111 Date of Study:12/8/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=M SUBJECT_SAMPLE_FACTORS 434-130 113 Date of Study:12/29/16 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=F SUBJECT_SAMPLE_FACTORS 434-131 115 Date of Study:12/29/16 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=F SUBJECT_SAMPLE_FACTORS 434-132 117 Date of Study:1/5/16 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Sex=M SUBJECT_SAMPLE_FACTORS 434-301 119 Date of Study:8/4/15 | Time:baseline | Study Group:normal weight reference group adolescents Sex=M SUBJECT_SAMPLE_FACTORS 434-302 121 Date of Study:8/4/15 | Time:baseline | Study Group:normal weight reference group adolescents Sex=M SUBJECT_SAMPLE_FACTORS 434-303 123 Date of Study:10/19/15 | Time:baseline | Study Group:normal weight reference group adolescents Sex=M SUBJECT_SAMPLE_FACTORS 434-304 125 Date of Study:10/15/15 | Time:baseline | Study Group:normal weight reference group adolescents Sex=F SUBJECT_SAMPLE_FACTORS 434-305 127 Date of Study:12/17/15 | Time:baseline | Study Group:normal weight reference group adolescents Sex=M SUBJECT_SAMPLE_FACTORS 434-306 129 Date of Study:12/17/15 | Time:baseline | Study Group:normal weight reference group adolescents Sex=F SUBJECT_SAMPLE_FACTORS 434-307 131 Date of Study:12/23/15 | Time:baseline | Study Group:normal weight reference group adolescents Sex=F SUBJECT_SAMPLE_FACTORS 434-308 133 Date of Study:1/9/16 | Time:baseline | Study Group:normal weight reference group adolescents Sex=M SUBJECT_SAMPLE_FACTORS 11333 135 Date of Study:6/8/2010 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program Sex=M SUBJECT_SAMPLE_FACTORS 11333 136 Date of Study:7/15/10 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program Sex=M SUBJECT_SAMPLE_FACTORS 11097 137 Date of Study:5/25/2010 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program Sex=M SUBJECT_SAMPLE_FACTORS 11097 138 Date of Study:6/25/10 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program Sex=M SUBJECT_SAMPLE_FACTORS 11327 139 Date of Study:6/1/2010 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program Sex=M SUBJECT_SAMPLE_FACTORS 11327 140 Date of Study:7/14/10 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program Sex=M SUBJECT_SAMPLE_FACTORS 11326 141 Date of Study:6/2/2010 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program Sex=M SUBJECT_SAMPLE_FACTORS 11326 142 Date of Study:7/14/10 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program Sex=M SUBJECT_SAMPLE_FACTORS 11313 143 Date of Study:6/23/2010 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program Sex=F SUBJECT_SAMPLE_FACTORS 11313 144 Date of Study:8/5/10 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program Sex=F SUBJECT_SAMPLE_FACTORS 11314 145 Date of Study:6/23/2010 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program Sex=F SUBJECT_SAMPLE_FACTORS 11314 146 Date of Study:8/5/10 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program Sex=F SUBJECT_SAMPLE_FACTORS 11537 147 Date of Study:8/10/2010 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program Sex=F SUBJECT_SAMPLE_FACTORS 11537 148 Date of Study:9/29/10 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program Sex=F SUBJECT_SAMPLE_FACTORS 11547 149 Date of Study:8/30/2010 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program Sex=M SUBJECT_SAMPLE_FACTORS 11547 150 Date of Study:9/30/2010 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program Sex=M SUBJECT_SAMPLE_FACTORS 11580 151 Date of Study:12/8/10 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program Sex=F SUBJECT_SAMPLE_FACTORS 11580 152 Date of Study:2/15/2011 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program Sex=F SUBJECT_SAMPLE_FACTORS 11588 153 Date of Study:1/6/11 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program Sex=F SUBJECT_SAMPLE_FACTORS 11588 154 Date of Study:2/14/2011 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program Sex=F SUBJECT_SAMPLE_FACTORS 11620 155 Date of Study:2/18/11 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program Sex=M SUBJECT_SAMPLE_FACTORS 11620 156 Date of Study:4/22/2011 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program Sex=M SUBJECT_SAMPLE_FACTORS 11638 157 Date of Study:5/20/2011 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program Sex=M SUBJECT_SAMPLE_FACTORS 11638 158 Date of Study:7/7/11 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program Sex=M SUBJECT_SAMPLE_FACTORS 11635 159 Date of Study:5/3/2011 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program Sex=F SUBJECT_SAMPLE_FACTORS 11635 160 Date of Study:6/8/11 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program Sex=F SUBJECT_SAMPLE_FACTORS 11636 161 Date of Study:5/3/2011 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program Sex=M SUBJECT_SAMPLE_FACTORS 11636 162 Date of Study:6/8/2011 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program Sex=M SUBJECT_SAMPLE_FACTORS 11637 163 Date of Study:5/26/11 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program Sex=M SUBJECT_SAMPLE_FACTORS 11637 164 Date of Study:8/5/2011 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program Sex=M SUBJECT_SAMPLE_FACTORS 11644 165 Date of Study:7/13/11 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program Sex=M SUBJECT_SAMPLE_FACTORS 11644 166 Date of Study:8/25/2011 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program Sex=M SUBJECT_SAMPLE_FACTORS 11675 167 Date of Study:6/23/11 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program Sex=M SUBJECT_SAMPLE_FACTORS 11675 168 Date of Study:8/10/2011 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program Sex=M SUBJECT_SAMPLE_FACTORS 11685 169 Date of Study:7/27/11 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program Sex=M SUBJECT_SAMPLE_FACTORS 11685 170 Date of Study:9/6/2011 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program Sex=M SUBJECT_SAMPLE_FACTORS 11681 171 Date of Study:7/19/11 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program Sex=M SUBJECT_SAMPLE_FACTORS 11681 172 Date of Study:8/24/2011 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program Sex=M SUBJECT_SAMPLE_FACTORS 11683 173 Date of Study:7/20/11 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program Sex=M SUBJECT_SAMPLE_FACTORS 11683 174 Date of Study:8/24/2011 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program Sex=M SUBJECT_SAMPLE_FACTORS 11684 175 Date of Study:7/18/11 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program Sex=M SUBJECT_SAMPLE_FACTORS 11684 176 Date of Study:8/17/2011 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program Sex=M SUBJECT_SAMPLE_FACTORS 11517 177 Date of Study:7/1/10 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program Sex=F SUBJECT_SAMPLE_FACTORS 11517 178 Date of Study:8/6/2010 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program Sex=F #COLLECTION CO:COLLECTION_SUMMARY Male and female American Indians 11-21 years old are being recruited from the CO:COLLECTION_SUMMARY Choctaw Nation Health Service Area of southeast Oklahoma. We use a collaborative CO:COLLECTION_SUMMARY approach as recently described by our American Indian Programs Coordinator (12). CO:COLLECTION_SUMMARY The primary characteristics of the three study groups are shown in Table 1. CO:COLLECTION_SUMMARY Group 1 is obese (Body mass index, BMI, ≥95th percentile for age- and CO:COLLECTION_SUMMARY sex-specific norms based on growth charts from the Centers for Disease Control), CO:COLLECTION_SUMMARY with pubertal maturation level ≥Tanner Stage 2, family history of T2D, and CO:COLLECTION_SUMMARY recent history of low physical activity. Low physical activity, defined as CO:COLLECTION_SUMMARY attaining <30 minutes of structured moderate-to-vigorous intensity exercise on 3 CO:COLLECTION_SUMMARY days/week over the preceding 3 months, is confirmed through questionnaires and CO:COLLECTION_SUMMARY use of an accelerometer. Groups 2 and 3 are both classified as normal weight CO:COLLECTION_SUMMARY (BMI greater than 20th and less than 85th percentile) with maturation level CO:COLLECTION_SUMMARY ≥Tanner Stage 2. Group 2 will have low physical activity (same as Group 1), CO:COLLECTION_SUMMARY while Group 3 will have high physical activity, defined as >30 minutes of CO:COLLECTION_SUMMARY structured moderate-to-vigorous intensity exercise on >3 days/week in the CO:COLLECTION_SUMMARY preceding 3 months. Additional eligibility criteria are: lack of diabetes or CO:COLLECTION_SUMMARY other potentially confounding metabolic disorders, able to safely exercise, CO:COLLECTION_SUMMARY willingness to complete the testing and participation schedule, and not on CO:COLLECTION_SUMMARY medications known to impact the stated outcomes. A medical history and physical CO:COLLECTION_SUMMARY exam is performed to assure suitability for the study during the initial CO:COLLECTION_SUMMARY screening. #TREATMENT TR:TREATMENT_SUMMARY Only Group 1 participants continue on to the exercise training program, which TR:TREATMENT_SUMMARY lasts 48 weeks. Follow-up measurements of the clinical and functional tests are TR:TREATMENT_SUMMARY performed at 16, 32, and 48 weeks; values at 16 weeks will be used for the TR:TREATMENT_SUMMARY current proposal to assure adequate sample size. Exercise sessions are performed TR:TREATMENT_SUMMARY at the Choctaw Wellness Centers, where fitness professionals provide instruction TR:TREATMENT_SUMMARY and supervision. Participants receive incentives for completing 20-60 minutes of TR:TREATMENT_SUMMARY moderate-to-vigorous physical activity (MVPA) on 3 days per week. MVPA is TR:TREATMENT_SUMMARY defined as exercise that elicits a heart rate ≥ 70% of peak heart rate. TR:TREATMENT_SUMMARY Several types of exercise can be selected, including walking, running, cycling, TR:TREATMENT_SUMMARY aerobic dance or other activities. To promote healthy behavior within the TR:TREATMENT_SUMMARY community and foster social support, all participants are invited to exercise TR:TREATMENT_SUMMARY with family members or friends if they choose. Exercise intensity is monitored TR:TREATMENT_SUMMARY by recording heart rate with a chest strap transmitter that outputs to a TR:TREATMENT_SUMMARY computer for quantification and data storage. Training sessions are also TR:TREATMENT_SUMMARY recorded in an exercise log by each participant and confirmed by fitness center TR:TREATMENT_SUMMARY staff. #SAMPLEPREP SP:SAMPLEPREP_SUMMARY Part 1: Longer-term exercise training study: Samples #1-133. Overweight/Obese SP:SAMPLEPREP_SUMMARY adolescents (IDs 434-001 through 434-132) enrolled into a 48-week exercise SP:SAMPLEPREP_SUMMARY program (3 days per week). Samples submitted are from the pre-training SP:SAMPLEPREP_SUMMARY (Baseline) and the end of the first 16 weeks (Post-training) times. Compliance SP:SAMPLEPREP_SUMMARY with the exercise program varies widely among participants. An additional set of SP:SAMPLEPREP_SUMMARY normal weight reference group adolescents (IDs 434-301 through 434-308) are SP:SAMPLEPREP_SUMMARY included. Note that 15 OW/OB participants in the exercise group and all 8 NW SP:SAMPLEPREP_SUMMARY reference group participants have only a single baseline sample. All samples SP:SAMPLEPREP_SUMMARY were collected following overnight fast into EDTA (lavender top) glass tubes for SP:SAMPLEPREP_SUMMARY preparation of plasma, kept on ice 20 minutes, spun, aliquoted and then kept SP:SAMPLEPREP_SUMMARY frozen. None have been previously used. Part 2: Short-term exercise training SP:SAMPLEPREP_SUMMARY study: Samples with ID 11xxx. Overweight/Obese adolescents completed a SP:SAMPLEPREP_SUMMARY short-term exercise program, consisting of 10 sessions over 5 weeks. Samples SP:SAMPLEPREP_SUMMARY were collected following overnight fast, before (Baseline) and after SP:SAMPLEPREP_SUMMARY (Post-training) the training program. These samples are serum since plasma was SP:SAMPLEPREP_SUMMARY used for other analyses. All tubes are marked with a unique ID number (shown in SP:SAMPLEPREP_SUMMARY list below) in black marker. Additional sample details on the labels are listed SP:SAMPLEPREP_SUMMARY in the accompanying Excel spreadsheet. #CHROMATOGRAPHY CH:CHROMATOGRAPHY_TYPE Reversed phase CH:INSTRUMENT_NAME Agilent 1290 Infinity CH:COLUMN_NAME Waters Acquity BEH C18 (150 x 2.1mm, 1.7um) #ANALYSIS AN:ANALYSIS_TYPE MS #MS MS:INSTRUMENT_NAME Agilent 6460 QQQ MS:INSTRUMENT_TYPE Triple quadrupole MS:MS_TYPE ESI MS:ION_MODE NEGATIVE #MS_METABOLITE_DATA MS_METABOLITE_DATA:UNITS uM MS_METABOLITE_DATA_START Samples 1 2 3 4 7 8 9 10 11 12 13 14 15 16 17 19 20 21 22 23 24 25 27 28 29 30 31 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 73 74 75 77 79 81 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 101 102 103 104 105 106 107 108 109 111 113 115 117 119 121 123 125 127 129 131 133 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 Factors Date of Study:7/24/2013 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:11/26/13 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:7/31/2013 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:11/25/13 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:8/16/2013 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:12/23/13 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:9/27/2013 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:1/31/14 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:10/2/2013 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:1/31/14 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:10/4/2013 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:2/7/14 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:10/11/2013 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:3/17/14 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:10/2/2013 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:9/27/2013 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:2/21/14 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:10/25/2013 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:3/17/14 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:12/23/2014 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:4/28/14 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:3/14/2014 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:5/16/2014 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:9/5/14 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:7/18/2014 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:11/25/14 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:10/30/2014 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:12/12/2014 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:5/8/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:2/20/2015 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:7/20/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:2/20/2015 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:7/20/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:3/13/2015 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:7/21/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:3/13/2015 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:7/21/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:3/27/2015 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:8/7/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:3/27/2015 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:8/4/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:3/27/2015 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:8/4/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:3/16/2015 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:8/11/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:3/16/2015 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:8/11/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:5/5/2015 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:5/22/2015 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:9/25/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:6/11/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:10/28/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:7/14/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:11/6/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:7/14/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:11/6/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:6/30/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:11/23/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:6/30/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:11/17/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:8/17/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:2/9/16 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:8/28/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:2/9/16 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:9/1/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:10/23/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:3/4/16 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:12/18/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:12/18/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:2/8/16 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:2/8/16 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:8/29/14 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:12/16/14 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:9/18/2014 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:1/20/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:10/10/14 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:3/4/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:11/28/2014 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:5/8/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:12/4/2014 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:4/10/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:12/11/14 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:4/30/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:1/5/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:5/8/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:1/5/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:5/8/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:2/13/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:6/8/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:10/5/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:8/4/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:12/29/16 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:8/5/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:12/11/15 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:8/18/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:1/15/16 | Time:post-program | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:8/21/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:12/8/15 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:12/29/16 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:12/29/16 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:1/5/16 | Time:baseline | Study Group:Overweight/Obese adolescents 48 week excersise program Date of Study:8/4/15 | Time:baseline | Study Group:normal weight reference group adolescents Date of Study:8/4/15 | Time:baseline | Study Group:normal weight reference group adolescents Date of Study:10/19/15 | Time:baseline | Study Group:normal weight reference group adolescents Date of Study:10/15/15 | Time:baseline | Study Group:normal weight reference group adolescents Date of Study:12/17/15 | Time:baseline | Study Group:normal weight reference group adolescents Date of Study:12/17/15 | Time:baseline | Study Group:normal weight reference group adolescents Date of Study:12/23/15 | Time:baseline | Study Group:normal weight reference group adolescents Date of Study:1/9/16 | Time:baseline | Study Group:normal weight reference group adolescents Date of Study:6/8/2010 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program Date of Study:7/15/10 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program Date of Study:5/25/2010 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program Date of Study:6/25/10 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program Date of Study:6/1/2010 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program Date of Study:7/14/10 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program Date of Study:6/2/2010 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program Date of Study:7/14/10 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program Date of Study:6/23/2010 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program Date of Study:8/5/10 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program Date of Study:6/23/2010 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program Date of Study:8/5/10 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program Date of Study:8/10/2010 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program Date of Study:9/29/10 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program Date of Study:8/30/2010 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program Date of Study:9/30/2010 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program Date of Study:12/8/10 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program Date of Study:2/15/2011 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program Date of Study:1/6/11 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program Date of Study:2/14/2011 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program Date of Study:2/18/11 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program Date of Study:4/22/2011 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program Date of Study:5/20/2011 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program Date of Study:7/7/11 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program Date of Study:5/3/2011 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program Date of Study:6/8/11 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program Date of Study:5/3/2011 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program Date of Study:6/8/2011 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program Date of Study:5/26/11 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program Date of Study:8/5/2011 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program Date of Study:7/13/11 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program Date of Study:8/25/2011 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program Date of Study:6/23/11 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program Date of Study:8/10/2011 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program Date of Study:7/27/11 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program Date of Study:9/6/2011 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program Date of Study:7/19/11 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program Date of Study:8/24/2011 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program Date of Study:7/20/11 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program Date of Study:8/24/2011 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program Date of Study:7/18/11 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program Date of Study:8/17/2011 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program Date of Study:7/1/10 | Time:baseline | Study Group:Overweight/Obese adolescents 5 week exercise program Date of Study:8/6/2010 | Time:post-program | Study Group:Overweight/Obese adolescents 5 week exercise program EPA 0.933950063 1.164219584 1.173683625 2.092721169 1.631062769 3.012672659 1.698679173 2.40875098 2.531547377 2.434227924 1.913765893 1.228552958 1.445146701 3.700809237 1.943034856 1.512747795 2.486815404 2.202751742 1.987091079 1.283629469 1.370345908 1.173639998 1.905017448 1.06635379 1.5452791 1.47151987 2.686142271 0.924594685 1.269364314 1.28070856 1.470978051 1.814294701 1.644380436 2.793846338 4.421402152 1.096828748 2.110715563 1.501905157 1.952372987 3.750077219 6.061520568 2.527762552 1.488366362 2.065752369 1.719090048 9.244945959 9.905636999 2.361703367 2.295658377 1.870867778 2.011900352 3.211111956 1.811305365 1.845314769 1.01566859 0.602328699 1.640187505 0.997911689 2.174654196 1.276107056 1.806099559 1.32786672 3.408504816 1.632441341 2.895861031 1.125974137 0.962867248 2.519680878 1.950618766 1.018227523 0.537784831 1.358828853 1.243592373 1.347773477 0.904364888 1.374408512 0.904912525 1.144432085 1.344752584 1.178361667 1.358955758 0.862500362 0.569986275 1.535860543 1.957800282 1.17933367 1.246972807 0.792708514 1.455095954 1.249100756 2.36530634 1.358075167 1.823011001 0.614631916 2.493339716 1.391377576 1.922070874 0.943313979 2.361384167 2.171572189 1.770443147 3.336098432 3.558816194 1.159209856 5.829943045 0.493507846 0.980092582 2.238717634 0.913898388 3.154687722 3.764819423 2.872003928 1.077312179 1.508362681 1.620043759 2.596293614 2.015036368 1.672433318 1.87178534 1.0371372 1.33296338 1.13788655 1.083738356 3.617619535 9.27573648 1.58745811 9.51830962 7.385802843 1.699491875 2.887711429 2.650949828 0.837737332 0.900902702 2.895590542 1.262811796 1.706107582 1.377039366 1.120741879 1.623106475 1.181296796 0.977562009 1.196151191 1.246562792 5.058074256 5.221843376 2.940732033 1.90157345 3.246603702 3.562060505 0.953616332 37.57067774 4.73468513 3.494117164 linolenic 9.383295606 5.172455377 6.148660281 3.269035054 10.64260409 14.53291793 10.3697851 11.21287342 15.17756596 12.63566211 14.26069214 8.951828383 15.7335161 13.04630393 20.35470947 16.68238424 20.75490945 14.70119418 6.263014219 9.078028926 8.804134414 6.267325207 4.076733213 3.779963748 16.65533482 13.31308525 17.84592867 12.7016537 5.619429378 7.936991434 8.264539358 9.328969705 10.33568982 19.24834777 17.27623949 13.23298944 14.1899139 8.990726434 11.39384457 14.9591503 8.704157737 34.3196204 6.763146172 8.898998772 5.081107967 19.83930465 11.93855431 17.97175748 13.50651472 26.99359286 14.99052265 22.09483309 5.286603272 12.26036633 10.54892404 6.648420646 10.0163398 8.273654857 14.07946082 9.837139008 24.2905518 17.83394871 20.41717892 14.6808523 11.02436071 7.054668174 5.875056088 14.05694371 7.582549273 8.057063774 4.785486426 12.87034103 10.46968971 10.71182723 9.215622654 9.302165441 7.963574802 8.989885203 11.94237506 9.763130393 9.781314567 9.696259047 8.039095396 13.51254242 16.0748959 11.20193642 16.08178859 11.00672756 16.98867869 30.85409709 14.84884518 14.98202764 3.724281326 6.695965022 10.98771294 6.378863371 15.81805986 7.209666511 21.84637857 19.59045402 13.15752224 14.55845714 7.593488285 6.544071624 36.02677643 2.446632117 7.632976086 40.10564665 11.86851263 22.12043272 14.02099075 16.59601932 13.72358652 20.74657551 10.5659986 13.15286624 16.50208936 22.99741591 17.79014544 14.42402978 15.22666859 15.47030565 7.463229591 12.43316658 25.81754305 17.31836821 8.404725367 25.0728555 10.38501916 12.635464 11.74546932 13.56607901 20.14523997 21.11107227 7.575902326 12.08934675 6.188181079 7.378200857 11.36939265 13.16368322 8.298408999 15.45755999 13.6432701 12.14059107 11.17445877 18.60508715 24.5769514 22.92963832 23.46762749 18.82812102 13.95047352 38.65259716 27.26478924 DHA 6.142948873 6.175073565 4.704231605 6.25733619 6.999308553 11.12971285 13.25045253 18.51685565 15.5063686 13.09851985 10.74520646 10.21149609 9.711528221 13.12855819 11.38725909 10.24170988 14.32786083 12.42383926 11.07087287 8.022631807 6.707419304 7.597091932 8.512504752 4.010156764 10.18208741 10.09008382 19.35125257 8.295125299 6.626157002 6.597112743 8.682113279 5.359990283 5.340210305 7.118472885 8.976586421 6.059795866 7.843735025 4.972356318 7.101762082 7.826983746 7.485747729 17.32905449 8.72860848 13.97321991 7.728948799 17.20470788 12.99881331 11.6747514 6.988305409 6.69174064 9.309030752 12.67572903 6.87505642 9.377903534 6.070169653 3.367240336 8.61604494 6.260387776 11.88507972 7.629266871 9.072154277 9.340248157 12.80882491 9.446746197 11.4940748 6.310717688 5.537100016 10.95949361 10.29527356 6.884991837 3.29574872 10.90237753 8.348049166 7.56432959 7.872188943 10.44481662 6.128708702 9.020921083 8.195343132 11.97648405 10.5370919 7.284630585 3.968677724 11.5115202 12.22194483 10.30701355 6.249617783 7.451578415 7.954831809 11.09628256 11.61854814 10.4072044 5.988254274 6.3773188 7.50134572 5.573215352 12.98444753 9.309882907 10.50676357 14.61857032 11.88344925 20.3143541 15.32744523 5.654572628 19.86113145 5.350266814 10.32194372 17.39662653 12.1248076 15.42992048 14.52553856 14.77964418 8.403475676 10.16008118 8.452741377 12.18467327 8.81291164 10.48331625 10.02061905 8.921867651 9.594563486 7.898414585 4.668428963 5.711044861 14.67637248 11.04635701 8.006027108 15.78982351 6.240956681 7.139518003 10.10541577 5.607124521 4.338336501 19.98994785 9.771720115 7.286330894 6.507890497 6.083875601 5.905541369 6.610550458 5.845720838 8.320556766 6.351979906 16.77738646 19.93381111 18.33741566 11.20005339 17.32306158 15.59966667 7.512676437 5.571772981 17.13351691 15.30625441 myristic 7.227192245 3.38267714 3.624475155 2.78873229 6.806190751 11.2511489 7.059874571 7.744985488 14.66157775 10.4733055 12.04505296 9.387254276 9.692493841 9.47261878 13.4162145 10.93472471 17.64940487 11.65569268 5.418988728 5.308483259 5.37495206 5.289375996 6.075986754 3.965011951 7.690587695 8.022676891 10.06993526 6.797516893 3.294314526 4.108071103 3.964428039 4.057882788 3.961477472 11.94905015 11.85713954 7.3063859 11.25636652 3.87765344 4.354500295 10.95969549 6.986158442 8.838871613 3.327524178 6.68348179 5.303141852 13.44475266 9.111648972 10.26305599 3.208474959 6.4262026 9.526019328 12.93278846 5.330036518 7.823480791 6.584890445 4.211517552 7.776714492 5.103078574 6.994796764 3.880152689 12.45372687 8.97226462 12.03128074 9.068967649 6.182131625 4.401180977 3.362726961 11.73246813 6.439765071 5.836421294 3.233818423 7.604391372 5.536608046 7.704424774 5.05529067 8.494970172 7.764670711 6.627237361 7.307129973 7.403588122 4.733565657 8.155993146 3.938645275 11.42370394 12.65472299 6.181695083 11.5127796 8.095663181 15.08324149 13.12181479 8.346617226 8.89329357 4.432025653 2.421599031 8.163761203 4.126854596 7.279501376 5.512383347 16.07934571 16.5673825 7.641706456 9.011547544 6.61783319 4.837190907 29.74006502 1.885042514 10.03679598 19.90308132 11.93619452 10.15938945 13.17596886 11.5369815 7.987955163 8.939885606 7.799983091 9.65440852 12.24172964 18.81469047 13.98455905 13.24309218 12.01256014 12.71126655 5.050872133 11.62256229 16.27379708 9.57243252 6.140341852 23.09269822 8.687775548 13.89937969 11.73524095 6.861746167 6.750112299 19.94821256 13.12973973 9.323427413 7.170795 9.029986268 13.37120138 6.758669382 7.897142501 9.446091829 7.360172527 13.24327713 14.65658913 10.2293479 15.17339149 17.8119417 18.29466743 10.55665066 7.253943769 29.08766036 19.4264834 palmitoleic 17.35876318 10.41546102 6.397536573 3.763679655 16.69748133 29.08421505 17.08036711 16.57881243 37.61695908 32.89047155 28.14247504 19.27061056 32.71157491 25.59247564 43.58560072 28.8458614 44.81517727 44.05023177 21.38303116 6.992613267 8.982451719 15.96356213 8.197110538 6.991653011 25.9113405 25.14867324 24.08125254 20.9603564 9.622720021 13.31780673 11.49726114 13.47335699 13.46927429 29.1577995 26.49138863 21.58520659 26.26515612 8.847890286 8.129917529 37.49801313 19.90006846 19.95190878 9.063053236 16.10469065 11.41275877 41.02840246 31.22077316 19.03608723 8.230333878 26.52920464 24.52195224 35.28232267 9.607670059 17.79913437 14.59707215 10.28313879 13.41553359 12.52902434 24.08189742 12.07707748 24.74175961 19.50337502 24.19207277 18.25760253 14.08951131 13.42655398 8.853103122 23.16755642 12.53505367 15.30572204 6.502513637 19.39041021 9.054142728 22.14018378 16.18129869 19.35757536 13.07353866 12.71842007 14.79246741 16.08669752 8.289077451 18.76662925 6.044579817 23.39618044 32.43161912 11.219478 28.8245233 15.09177836 41.88724454 37.63477923 19.94383499 21.6823911 5.865491681 4.568512818 25.83550439 11.45124323 24.63747031 14.01631568 30.85094402 34.63050383 20.34102023 11.04258239 5.594962502 9.972404773 83.00571108 3.060680433 14.36792919 29.69065801 19.73064609 19.15917593 28.41275499 13.15134412 8.773566172 8.95418269 10.35615848 18.9157275 27.75744746 32.45706178 29.11837554 38.46372768 34.44063334 18.02974087 6.17534437 22.88238705 55.68320365 21.15548119 15.93747296 60.73168975 20.31084679 29.89123249 25.10049219 13.62023453 9.194321871 50.65047119 17.53823773 16.02558043 8.931033117 10.59070959 20.75904442 14.22851047 16.86589963 18.67616864 14.09627589 34.30882731 39.77564823 19.36732448 36.03672632 32.45080749 41.13165192 18.92792391 14.11156302 74.5554406 48.55673696 arachidonic 2.36078479 2.466864481 2.003841957 2.782012796 3.044232709 4.966864701 2.457910608 4.370917494 5.197470115 4.812176417 4.38865262 3.898450533 2.616069078 6.036425005 4.712429896 3.311019171 4.29731843 5.525572173 6.276060272 3.361446092 3.508457151 3.422933992 4.011193492 2.186600732 3.214981749 2.846198989 6.094337607 2.637092176 2.857143634 3.183361461 4.094725426 2.703655541 3.045322491 4.038900656 5.744627497 2.643094783 3.990556217 2.167676033 2.806214518 4.318489627 3.395538862 6.945578417 3.238201834 5.595910817 4.189097277 6.24193031 5.376399983 4.608573379 3.52939387 3.524212849 5.300379074 7.067577235 3.774811914 4.586812513 2.99037534 1.693177701 3.848641251 2.519592636 5.596482025 2.417402111 3.85620945 3.570969804 5.93875195 4.546848475 5.050955552 3.898845159 3.191455595 5.106059965 5.626513269 3.343258122 1.382066453 3.388766303 3.49264282 3.138612429 2.484263941 3.815626403 1.794289073 2.546505164 3.149191128 3.490894803 3.345805417 2.010732932 1.26503596 2.725642788 3.138048801 3.495909697 2.490281954 2.55393893 3.492979176 3.751193388 5.4616818 2.992839618 2.734581152 1.533711383 5.121802843 2.317095971 4.845011649 2.343844567 5.184595151 5.106160386 4.061913691 7.578709918 6.078341766 2.916332001 11.3966743 1.255879416 3.33621133 5.956403447 3.406711558 7.536021479 9.393901737 11.30121375 4.086530259 7.489501257 7.79716134 8.713673513 9.669298419 6.462040896 8.845540297 4.538333881 5.60211158 5.954474964 2.499828784 2.152630043 5.688281501 3.880372293 3.330816707 6.751515881 3.368045527 5.168884203 6.916388932 3.457557677 5.022300716 7.549507029 4.543402164 4.63924384 3.784055946 3.573208249 3.943405813 4.095949289 2.740569956 4.542340745 4.568213025 7.219062137 6.784085976 5.853659943 10.02727654 3.822745192 4.991710487 4.974322922 4.507624241 9.856109349 8.552363942 palmiteladic 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 linoleic 83.99298953 54.57373411 46.04445983 24.66120452 82.4425574 103.5885044 79.12510765 83.01509797 136.376601 124.0977102 134.9802715 97.49415415 123.7822519 105.4304138 166.0143001 117.8707895 157.5146633 134.5514276 78.13996901 62.64200969 64.3749325 66.60538974 39.57553963 33.73234506 114.3617464 94.51165194 135.2916754 103.4249639 51.38026714 62.74841221 62.42134915 69.95140734 72.22457339 127.7218582 118.8899771 94.83904403 108.5455401 58.85148419 71.84445062 142.6068215 84.01188427 171.5966417 53.51224639 95.62461073 49.06568481 157.1645433 105.3998596 150.4375691 86.30195153 189.7825289 133.6328354 169.0680072 45.64831053 88.21397839 78.47795057 52.19202405 65.17258768 63.45227801 104.184541 68.66275384 141.2119441 124.1885353 160.6254806 136.2691059 78.67151817 71.13223263 61.72218444 107.4082911 62.2414394 78.24251814 41.97756557 106.5702383 77.52941026 93.94160152 75.08810554 84.05719953 61.27706167 78.97792669 96.37496634 78.51624687 62.03403103 83.46298391 55.2174563 108.5919467 137.1340209 82.26309064 114.9839767 102.2284734 132.0119947 189.4941567 127.9605155 108.4620516 35.01793595 43.52882665 88.69251027 48.26808608 115.2533562 59.50150814 167.1191568 142.5362356 96.48114174 80.71692871 45.34745927 58.83872411 240.5498288 29.21288137 72.23473571 219.3921134 102.7286568 151.222683 148.2833697 133.044817 101.8022679 94.25486639 84.68402395 108.6567151 140.6651397 193.701135 159.1146725 163.0072719 177.1257937 127.9543285 54.30002623 79.42577168 199.4489118 125.825367 68.09899042 172.0698931 73.20368055 124.8863855 111.661445 120.0816948 151.393801 166.2668176 54.5153214 97.52595787 51.93632012 59.36853485 100.8846422 88.01345967 63.94710869 121.8698833 96.56906565 126.4524384 123.4816884 122.2539941 191.8714021 137.1103485 165.7584294 183.0547352 118.8571286 245.2951827 179.8657414 palmitic 115.8729025 71.67874837 54.22545046 36.74492661 119.028218 155.6755644 127.2069945 143.5375483 205.6010276 191.5403532 192.0283023 149.0859683 149.9743616 139.4187745 239.8141541 160.992302 218.4607604 171.2862364 109.3957811 77.83309831 72.22139161 97.82409796 67.97632236 47.38097424 129.5380951 127.8720256 173.8379706 131.6749425 68.89073439 75.75812821 73.573122 78.00525607 76.85859074 160.7079096 180.4166605 115.2605305 168.7305511 53.3136027 66.39593539 184.526154 116.492082 164.5572359 77.88125886 121.216367 88.16144471 224.1621145 181.1803735 184.4654556 91.8565823 192.5113346 142.1683418 191.380653 84.87660809 113.5316831 96.08476522 62.19840663 90.62919405 88.21178109 127.3908817 98.11473663 172.756203 154.430549 193.9028299 148.0980335 141.4982976 86.57951801 69.3129549 159.0752222 102.5180289 106.7269201 61.32232801 120.5944852 89.26608987 116.7617152 84.01697032 143.505501 95.30879103 104.1577638 112.2542449 105.1308905 75.78764886 145.2208386 73.01425338 145.6008609 202.9946954 102.8247043 143.9959011 133.8159912 203.5301146 211.4162648 116.6316887 124.2445254 55.25050775 49.45159122 148.7942107 78.28317961 136.8738177 74.40169969 212.0016516 195.0860273 124.3159843 96.4071214 73.39397044 78.94851729 304.6568344 36.3836171 102.5426304 217.9492643 147.8706293 150.2178965 187.0033898 132.3038047 95.67424103 111.9877974 102.5615332 132.4750602 146.75321 193.4363346 168.8422142 174.3646098 182.5456598 186.7654281 64.45146888 123.6377076 237.2542097 144.6322746 92.70500974 245.8212712 105.3193896 184.6041851 154.6804915 105.1872431 118.2651361 238.7576533 125.9537552 122.3332177 82.49822685 99.1033858 163.0775125 88.11275481 81.07556997 184.1235 129.009084 154.0561364 169.9313006 140.8023649 212.9446317 199.9942824 228.7435602 192.4975309 141.8101683 283.0469303 216.4473041 oleic 150.8677426 104.2739786 66.45210995 39.03036076 144.7382228 194.3250232 153.5660029 162.5251497 283.9138153 271.3166293 252.3956527 193.4358591 224.299321 190.7698587 335.5284817 211.2074692 299.2193358 281.7528245 172.6498038 82.14220685 92.20251264 131.8277649 77.67398558 60.41847601 212.6430179 188.89274 248.09423 171.8870927 83.06719994 121.4714283 114.9281624 117.9624294 115.6147111 220.8772034 214.2463676 160.6308408 216.1764738 65.70176341 78.1239858 282.7096274 168.5898595 195.5274854 90.90669138 188.2174496 104.677257 307.4251126 251.7262078 251.6451271 93.65543859 241.2811131 212.6830947 261.5595162 92.2413705 143.2931854 118.4048707 79.81203682 101.1643498 107.8458657 189.80588 125.8629394 197.6579264 203.9329716 273.7809036 203.0639297 159.9211133 126.2478767 95.38888013 209.0022824 135.6676186 138.2130153 75.11349372 191.6034888 120.8055434 170.8035047 107.9607692 201.6015265 115.1737773 138.7165709 153.4218607 157.5071922 98.31106104 193.7397432 80.87275229 188.763266 266.5220366 132.1420257 199.7499354 181.081875 293.9208875 273.7742062 165.6594386 194.790408 59.25419763 64.25433527 181.6981607 109.2889136 195.0355732 112.1378902 305.2705546 256.1247848 184.840357 118.8457987 71.5851368 108.3846613 523.6693957 44.32510273 135.7652869 324.0444252 201.3155717 206.811583 280.1024986 178.6849848 123.1858114 144.3654285 141.0215955 173.525617 226.5966415 285.8229754 254.6641004 282.9473105 260.7857897 220.4278125 76.49730288 165.4623374 380.9773727 192.1620275 127.835469 329.8040102 140.6654306 266.282526 214.2670141 147.6544532 161.0860959 316.564564 106.0739604 175.3754957 100.9132752 121.0493433 227.9745952 121.1207638 121.1942949 228.6746784 185.1686138 244.287799 295.601072 206.464475 326.159832 256.8206965 304.4023428 248.2154594 201.7070012 459.6972284 328.5764215 elaidic 10.75664214 6.10449024 5.388344085 8.166821536 10.52695158 13.55769909 10.51890338 10.56291403 21.63661748 17.32900949 16.33306311 14.17445169 15.78051681 12.54432187 22.47352744 17.23997523 24.04613074 16.11380659 9.869372336 7.706354957 7.770707474 9.473771653 7.283161063 4.486546385 12.12642254 13.01770455 15.71460915 10.83888273 5.80502441 6.741691036 5.836062092 8.389999622 6.458053439 19.27709596 16.78939026 11.90147292 14.90264645 4.300014347 5.880855517 19.92348234 11.10756218 12.75867875 5.977892184 13.53666343 8.477867138 22.50752975 18.86900992 18.15401015 5.092183235 18.70165117 10.28789556 15.37415624 10.14866969 11.74885064 8.572670058 5.564234047 7.726639811 5.375278979 7.834850409 6.728334603 14.01943671 12.08442432 16.79800069 12.48134282 9.222929683 6.391948248 4.485152785 15.18595197 9.747553662 14.65942761 13.25939215 13.23168612 7.197742727 9.610554954 9.925996772 14.48859378 10.31761647 10.94149022 11.27400512 14.00815971 6.992366749 22.74439947 5.520306492 12.08588798 18.00940348 9.515366899 10.70020021 12.48109338 14.30668996 409.1305426 10.83585141 9.455082967 5.144011981 6.938413659 10.92415268 5.591859743 10.09161106 7.298168223 26.45749967 22.76411769 12.58133739 10.27752935 10.25114544 10.45841788 41.26918659 2.564027698 9.634844148 34.0618962 11.61557349 49.31179582 22.81002257 22.9704298 12.70937238 17.49205857 12.13987888 19.90629997 17.67051001 29.27749376 25.36482818 23.75618436 21.05686522 20.0855596 8.366094512 14.83028798 21.88018231 17.04873395 16.06577218 28.79620319 12.06833679 19.13503774 15.33421966 14.48249429 13.52941566 27.59551873 12.00195581 13.50940804 11.5318888 14.86539274 20.81737522 9.014645042 9.542085308 32.55662991 13.90262081 18.07028484 15.84776943 18.17739441 22.36252936 20.22026158 24.43483903 18.35677992 20.92311153 40.14606996 29.51439576 stearic 30.44708366 19.79638087 21.14114137 16.48949292 30.44252927 44.13583375 33.70960709 43.68585335 48.46892237 37.12492444 45.45341514 38.67505682 33.51848049 35.31259478 41.66082282 38.6796011 42.38712104 31.74669844 21.12795142 28.77233322 26.51467515 27.37411561 21.42106269 15.18618254 34.51785918 38.53071218 46.06070262 39.22087722 24.53512471 28.95346136 23.82412443 23.13477629 21.94996348 45.21782125 52.32878 32.96167395 46.59974726 19.1994153 22.98726499 39.66909121 34.22065978 48.90999636 22.81893429 48.10936923 32.94449265 50.81098562 45.29432208 53.77027852 28.66623191 41.96132719 37.92930343 44.15266566 32.86274833 36.05016076 27.24282263 17.00465992 29.72048887 29.44579893 29.23431529 30.86192898 48.0606999 48.65994487 51.83779797 45.62372306 38.37651354 21.37375086 26.43685229 42.09714781 33.19318941 40.49818682 28.04930202 38.21666645 35.41775121 30.99633565 22.25863093 48.0602646 25.04501346 31.95745668 33.13147443 34.80822254 27.99930486 40.92803955 25.967663 37.00291381 51.83816951 31.47000536 23.16043426 40.1562459 43.66134213 58.10103581 35.62165889 37.01879693 18.63130107 27.31899732 34.86730814 28.57283105 39.96739195 24.44631243 54.68149483 50.90484187 32.77583942 38.61696741 31.84342823 30.10176118 56.03575478 12.34930382 35.05997104 67.9916401 44.20843193 52.86524679 46.91911944 52.14159891 39.97681978 45.30512225 32.87895435 40.91466794 36.69616538 44.25356053 45.16938063 41.50059708 40.99954917 54.62021204 24.73003507 30.83082152 47.39020071 35.79921079 25.50668541 44.13469344 25.23767046 43.5160625 38.79323895 37.54354452 49.70253202 45.98836119 33.37565029 44.7413837 34.70461066 35.2695823 43.11894094 30.13682544 20.22839633 61.72155708 46.45320575 37.37964052 48.20958673 42.46594091 49.15352867 48.30056815 49.56364576 49.01633895 46.59974341 49.45185998 53.06151449 MS_METABOLITE_DATA_END #METABOLITES METABOLITES_START metabolite_name EPA linolenic DHA myristic palmitoleic arachidonic palmiteladic linoleic palmitic oleic elaidic stearic METABOLITES_END #END