#METABOLOMICS WORKBENCH alhughes3_20210722_081823 DATATRACK_ID:2764 STUDY_ID:ST001901 ANALYSIS_ID:AN003089 VERSION 1 CREATED_ON 02-08-2024 #PROJECT PR:PROJECT_TITLE Mitochondrial-Derived Compartments Facilitate Cellular Adaptation to Amino Acid PR:PROJECT_TITLE Stress PR:PROJECT_SUMMARY Amino acids are essential building blocks of life. However, increasing evidence PR:PROJECT_SUMMARY suggests that elevated amino acids cause cellular toxicity associated with PR:PROJECT_SUMMARY numerous metabolic disorders. How cells cope with elevated amino acids remains PR:PROJECT_SUMMARY poorly understood. Here, we show that a previously identified cellular PR:PROJECT_SUMMARY structure, the mitochondrial-derived compartment (MDC), functions to protect PR:PROJECT_SUMMARY cells from amino acid stress. In response to amino acid elevation, MDCs are PR:PROJECT_SUMMARY generated from mitochondria, where they selectively sequester and deplete SLC25A PR:PROJECT_SUMMARY nutrient carriers and their associated import receptor Tom70 from the organelle. PR:PROJECT_SUMMARY Generation of MDCs promotes amino acid catabolism, and their formation occurs PR:PROJECT_SUMMARY simultaneously with transporter removal at the plasma membrane via the PR:PROJECT_SUMMARY multi-vesicular body (MVB) pathway. Combined loss of vacuolar amino acid PR:PROJECT_SUMMARY storage, MVBs and MDCs renders cells sensitive to high amino acid stress. Thus, PR:PROJECT_SUMMARY we propose that MDCs operate as part of a coordinated cell network that PR:PROJECT_SUMMARY facilitates amino acid homoeostasis through post-translational nutrient PR:PROJECT_SUMMARY transporter remodeling. PR:INSTITUTE University of Utah School of Medicine PR:DEPARTMENT Biochemistry PR:LABORATORY Hughes Lab PR:LAST_NAME Hughes PR:FIRST_NAME Adam PR:ADDRESS 15 N Medical Drive East, RM 4100, Salt Lake City, UT, 84112, USA PR:EMAIL hughes@biochem.utah.edu PR:PHONE 8015812481 PR:DOI http://dx.doi.org/10.21228/M83X4N #STUDY ST:STUDY_TITLE Mitochondrial-Derived Compartments Facilitate Cellular Adaptation to Amino Acid ST:STUDY_TITLE Stress ST:STUDY_SUMMARY Amino acids are essential building blocks of life. However, increasing evidence ST:STUDY_SUMMARY suggests that elevated amino acids cause cellular toxicity associated with ST:STUDY_SUMMARY numerous metabolic disorders. How cells cope with elevated amino acids remains ST:STUDY_SUMMARY poorly understood. Here, we show that a previously identified cellular ST:STUDY_SUMMARY structure, the mitochondrial-derived compartment (MDC), functions to protect ST:STUDY_SUMMARY cells from amino acid stress. In response to amino acid elevation, MDCs are ST:STUDY_SUMMARY generated from mitochondria, where they selectively sequester and deplete SLC25A ST:STUDY_SUMMARY nutrient carriers and their associated import receptor Tom70 from the organelle. ST:STUDY_SUMMARY Generation of MDCs promotes amino acid catabolism, and their formation occurs ST:STUDY_SUMMARY simultaneously with transporter removal at the plasma membrane via the ST:STUDY_SUMMARY multi-vesicular body (MVB) pathway. Combined loss of vacuolar amino acid ST:STUDY_SUMMARY storage, MVBs and MDCs renders cells sensitive to high amino acid stress. Thus, ST:STUDY_SUMMARY we propose that MDCs operate as part of a coordinated cell network that ST:STUDY_SUMMARY facilitates amino acid homoeostasis through post-translational nutrient ST:STUDY_SUMMARY transporter remodeling. ST:INSTITUTE University of Utah School of Medicine ST:DEPARTMENT Biochemistry ST:LABORATORY Hughes Lab ST:LAST_NAME Hughes ST:FIRST_NAME Adam ST:ADDRESS 15 N Medical Drive East, RM 4100, Salt Lake City, UT, 84112, USA ST:EMAIL hughes@biochem.utah.edu ST:PHONE 8015812481 ST:SUBMIT_DATE 2021-07-22 #SUBJECT SU:SUBJECT_TYPE Yeast SU:SUBJECT_SPECIES Saccharomyces cerevisiae SU:TAXONOMY_ID 4932 #SUBJECT_SAMPLE_FACTORS: SUBJECT(optional)[tab]SAMPLE[tab]FACTORS(NAME:VALUE pairs separated by |)[tab]Additional sample data SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_6A Genotype:gem1 knockout | Media:SD+Leucine | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_6A.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_6B Genotype:gem1 knockout | Media:SD+Leucine | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_6B.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_6C Genotype:gem1 knockout | Media:SD+Leucine | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_6C.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_6D Genotype:gem1 knockout | Media:SD+Leucine | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_6D.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_2A Genotype:gem1 knockout | Media:SD+Leucine | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_2A.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_2B Genotype:gem1 knockout | Media:SD+Leucine | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_2B.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_2C Genotype:gem1 knockout | Media:SD+Leucine | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_2C.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_2D Genotype:gem1 knockout | Media:SD+Leucine | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_2D.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_11 Genotype:gem1 knockout | Media:YPAD | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_11.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_17 Genotype:gem1 knockout | Media:YPAD | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_17.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_23 Genotype:gem1 knockout | Media:YPAD | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_23.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_5a Genotype:gem1 knockout | Media:YPAD | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_5a.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_11 Genotype:gem1 knockout | Media:YPAD | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_11.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_17 Genotype:gem1 knockout | Media:YPAD | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_17.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_23 Genotype:gem1 knockout | Media:YPAD | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_23.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_5 Genotype:gem1 knockout | Media:YPAD | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_5.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_10 Genotype:gem1 knockout | Media:YPAD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_10.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_16 Genotype:gem1 knockout | Media:YPAD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_16.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_22 Genotype:gem1 knockout | Media:YPAD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_22.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_4 Genotype:gem1 knockout | Media:YPAD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_4.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_10 Genotype:gem1 knockout | Media:YPAD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_10.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_16 Genotype:gem1 knockout | Media:YPAD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_16.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_22 Genotype:gem1 knockout | Media:YPAD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_22.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_4 Genotype:gem1 knockout | Media:YPAD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_4.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_12 Genotype:gem1 knockout | Media:YPAD | Treatment:Rap RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_12.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_18 Genotype:gem1 knockout | Media:YPAD | Treatment:Rap RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_18.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_24 Genotype:gem1 knockout | Media:YPAD | Treatment:Rap RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_24.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_5 Genotype:gem1 knockout | Media:YPAD | Treatment:Rap RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_5.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_12 Genotype:gem1 knockout | Media:YPAD | Treatment:Rap RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_12.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_18 Genotype:gem1 knockout | Media:YPAD | Treatment:Rap RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_18.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_24 Genotype:gem1 knockout | Media:YPAD | Treatment:Rap RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_24.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_6 Genotype:gem1 knockout | Media:YPAD | Treatment:Rap RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_6.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_4D Genotype:gem1 vps27 double knockout | Media:SD+Leucine | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_4D.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_8A Genotype:gem1 vps27 double knockout | Media:SD+Leucine | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_8A.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_8B Genotype:gem1 vps27 double knockout | Media:SD+Leucine | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_8B.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_8C Genotype:gem1 vps27 double knockout | Media:SD+Leucine | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_8C.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_8D Genotype:gem1 vps27 double knockout | Media:SD+Leucine | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_8D.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_4A Genotype:gem1 vps27 double knockout | Media:SD+Leucine | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_4A.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_4B Genotype:gem1 vps27 double knockout | Media:SD+Leucine | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_4B.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_4C Genotype:gem1 vps27 double knockout | Media:SD+Leucine | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_4C.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20190522_5977b_10to1_Yeast_QC5 Genotype:Pooled QC sample | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20190522_5977b_10to1_Yeast_QC5.cdf; Experiment identifier=MDCY-80; Submission date=05.17.19; Analysis=Whole cell mtabolites; Figures=S3 SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20190522_5977b_10to1_Yeast_QC6 Genotype:Pooled QC sample | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20190522_5977b_10to1_Yeast_QC6.cdf; Experiment identifier=MDCY-80; Submission date=05.17.19; Analysis=Whole cell mtabolites; Figures=S3 SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20190522_5977b_10to1_Yeast_QC7 Genotype:Pooled QC sample | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20190522_5977b_10to1_Yeast_QC7.cdf; Experiment identifier=MDCY-80; Submission date=05.17.19; Analysis=Whole cell mtabolites; Figures=S3 SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20190522_5977b_10to1_Yeast_QC8 Genotype:Pooled QC sample | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20190522_5977b_10to1_Yeast_QC8.cdf; Experiment identifier=MDCY-80; Submission date=05.17.19; Analysis=Whole cell mtabolites; Figures=S3 SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_QC1 Genotype:Pooled QC sample | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_QC1.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_QC2 Genotype:Pooled QC sample | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_QC2.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_QC3 Genotype:Pooled QC sample | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_QC3.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_QC4 Genotype:Pooled QC sample | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_QC4.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_QC1 Genotype:Pooled QC sample | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_QC1.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_QC2 Genotype:Pooled QC sample | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_QC2.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_QC3 Genotype:Pooled QC sample | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_QC3.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_QC4 Genotype:Pooled QC sample | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_QC4.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_QC1 Genotype:Pooled QC sample | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_QC1.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_QC2 Genotype:Pooled QC sample | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_QC2.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_QC3 Genotype:Pooled QC sample | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_QC3.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_QC4 Genotype:Pooled QC sample | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_QC4.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20190522_5977b_10to1_Yeast_PB4 Genotype:Process blank | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20190522_5977b_10to1_Yeast_PB4.cdf; Experiment identifier=MDCY-80; Submission date=05.17.19; Analysis=Whole cell mtabolites; Figures=S3 SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20190522_5977b_10to1_Yeast_PB5 Genotype:Process blank | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20190522_5977b_10to1_Yeast_PB5.cdf; Experiment identifier=MDCY-80; Submission date=05.17.19; Analysis=Whole cell mtabolites; Figures=S3 SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20190522_5977b_10to1_Yeast_PB6 Genotype:Process blank | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20190522_5977b_10to1_Yeast_PB6.cdf; Experiment identifier=MDCY-80; Submission date=05.17.19; Analysis=Whole cell mtabolites; Figures=S3 SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_PB1 Genotype:Process blank | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_PB1.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_PB2 Genotype:Process blank | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_PB2.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_PB3 Genotype:Process blank | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_PB3.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_PB4 Genotype:Process blank | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_PB4.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_PB1 Genotype:Process blank | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_PB1.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_PB2 Genotype:Process blank | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_PB2.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_PB3 Genotype:Process blank | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_PB3.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_PB4 Genotype:Process blank | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_PB4.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_PB1 Genotype:Process blank | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_PB1.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_PB2 Genotype:Process blank | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_PB2.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_PB3 Genotype:Process blank | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_PB3.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_PB4 Genotype:Process blank | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_PB4.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_7A Genotype:vps27 knockout | Media:SD+Leucine | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_7A.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_7B Genotype:vps27 knockout | Media:SD+Leucine | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_7B.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_7C Genotype:vps27 knockout | Media:SD+Leucine | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_7C.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_7D Genotype:vps27 knockout | Media:SD+Leucine | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_7D.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_3A Genotype:vps27 knockout | Media:SD+Leucine | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_3A.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_3B Genotype:vps27 knockout | Media:SD+Leucine | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_3B.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_3C Genotype:vps27 knockout | Media:SD+Leucine | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_3C.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_3D Genotype:vps27 knockout | Media:SD+Leucine | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_3D.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20190522_5977b_10to1_Yeast_34 Genotype:wild-type | Media:MinD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20190522_5977b_10to1_Yeast_34.cdf; Experiment identifier=MDCY-80; Submission date=05.17.19; Analysis=Whole cell mtabolites; Figures=S3 SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20190522_5977b_10to1_Yeast_43 Genotype:wild-type | Media:MinD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20190522_5977b_10to1_Yeast_43.cdf; Experiment identifier=MDCY-80; Submission date=05.17.19; Analysis=Whole cell mtabolites; Figures=S3 SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20190522_5977b_10to1_Yeast_52 Genotype:wild-type | Media:MinD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20190522_5977b_10to1_Yeast_52.cdf; Experiment identifier=MDCY-80; Submission date=05.17.19; Analysis=Whole cell mtabolites; Figures=S3 SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_5A Genotype:wild-type | Media:SD+Leucine | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_5A.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_5B Genotype:wild-type | Media:SD+Leucine | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_5B.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_5C Genotype:wild-type | Media:SD+Leucine | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_5C.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_5D Genotype:wild-type | Media:SD+Leucine | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_5D.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_1A Genotype:wild-type | Media:SD+Leucine | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_1A.D; Experiment identifier=MDCY-205; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_1B Genotype:wild-type | Media:SD+Leucine | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_1B.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_1C Genotype:wild-type | Media:SD+Leucine | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_1C.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_1D Genotype:wild-type | Media:SD+Leucine | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_1D.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20190522_5977b_10to1_Yeast_31 Genotype:wild-type | Media:SD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20190522_5977b_10to1_Yeast_31.cdf; Experiment identifier=MDCY-80; Submission date=05.17.19; Analysis=Whole cell mtabolites; Figures=S3 SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20190522_5977b_10to1_Yeast_40 Genotype:wild-type | Media:SD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20190522_5977b_10to1_Yeast_40.cdf; Experiment identifier=MDCY-80; Submission date=05.17.19; Analysis=Whole cell mtabolites; Figures=S3 SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20190522_5977b_10to1_Yeast_49 Genotype:wild-type | Media:SD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20190522_5977b_10to1_Yeast_49.cdf; Experiment identifier=MDCY-80; Submission date=05.17.19; Analysis=Whole cell mtabolites; Figures=S3 SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_14 Genotype:wild-type | Media:YPAD | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_14.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_2 Genotype:wild-type | Media:YPAD | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_2.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_20 Genotype:wild-type | Media:YPAD | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_20.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_8 Genotype:wild-type | Media:YPAD | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_8.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_14 Genotype:wild-type | Media:YPAD | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_14.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_2 Genotype:wild-type | Media:YPAD | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_2.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_20 Genotype:wild-type | Media:YPAD | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_20.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_8 Genotype:wild-type | Media:YPAD | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_8.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20190522_5977b_10to1_Yeast_28 Genotype:wild-type | Media:YPAD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20190522_5977b_10to1_Yeast_28.cdf; Experiment identifier=MDCY-80; Submission date=05.17.19; Analysis=Whole cell mtabolites; Figures=S3 SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20190522_5977b_10to1_Yeast_37 Genotype:wild-type | Media:YPAD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20190522_5977b_10to1_Yeast_37.cdf; Experiment identifier=MDCY-80; Submission date=05.17.19; Analysis=Whole cell mtabolites; Figures=S3 SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20190522_5977b_10to1_Yeast_46 Genotype:wild-type | Media:YPAD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20190522_5977b_10to1_Yeast_46.cdf; Experiment identifier=MDCY-80; Submission date=05.17.19; Analysis=Whole cell mtabolites; Figures=S3 SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_1 Genotype:wild-type | Media:YPAD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_1.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_13 Genotype:wild-type | Media:YPAD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_13.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_19 Genotype:wild-type | Media:YPAD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_19.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_7 Genotype:wild-type | Media:YPAD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_7.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_1 Genotype:wild-type | Media:YPAD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_1.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_13 Genotype:wild-type | Media:YPAD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_13.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_19 Genotype:wild-type | Media:YPAD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_19.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_7 Genotype:wild-type | Media:YPAD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_7.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_15 Genotype:wild-type | Media:YPAD | Treatment:Rap RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_15.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_21 Genotype:wild-type | Media:YPAD | Treatment:Rap RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_21.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_3 Genotype:wild-type | Media:YPAD | Treatment:Rap RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_3.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_9 Genotype:wild-type | Media:YPAD | Treatment:Rap RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_9.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_15 Genotype:wild-type | Media:YPAD | Treatment:Rap RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_15.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_21 Genotype:wild-type | Media:YPAD | Treatment:Rap RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_21.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_3 Genotype:wild-type | Media:YPAD | Treatment:Rap RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_3.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_9 Genotype:wild-type | Media:YPAD | Treatment:Rap RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_9.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E #COLLECTION CO:COLLECTION_SUMMARY See STAR methods file CO:COLLECTION_PROTOCOL_FILENAME STAR_methods.pdf CO:SAMPLE_TYPE Yeast cells #TREATMENT TR:TREATMENT_SUMMARY See STAR Methods file TR:TREATMENT_PROTOCOL_FILENAME STAR_methods.pdf #SAMPLEPREP SP:SAMPLEPREP_SUMMARY See STAR Methods file SP:SAMPLEPREP_PROTOCOL_FILENAME STAR_methods.pdf #CHROMATOGRAPHY CH:INSTRUMENT_NAME Agilent 5977B CH:COLUMN_NAME Phenomenex Zebron ZB-WAXplus (30m x 0.25mm,0.25um) CH:CHROMATOGRAPHY_TYPE GC #ANALYSIS AN:ANALYSIS_TYPE MS #MS MS:INSTRUMENT_NAME Agilent 5977B MS:INSTRUMENT_TYPE Single quadrupole MS:MS_TYPE EI MS:MS_COMMENTS N/A MS:ION_MODE POSITIVE #MS_METABOLITE_DATA MS_METABOLITE_DATA:UNITS area under the curve MS_METABOLITE_DATA_START Samples Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_11 Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_17 Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_23 Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_5a Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_10 Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_16 Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_22 Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_4 Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_12 Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_18 Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_24 Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_5 Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_QC1 Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_QC2 Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_QC3 Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_QC4 Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_PB1 Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_PB2 Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_PB3 Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_PB4 Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_14 Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_2 Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_20 Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_8 Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_1 Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_13 Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_19 Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_7 Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_15 Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_21 Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_3 Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_9 Factors Genotype:gem1 knockout | Media:YPAD | Treatment:ConcA Genotype:gem1 knockout | Media:YPAD | Treatment:ConcA Genotype:gem1 knockout | Media:YPAD | Treatment:ConcA Genotype:gem1 knockout | Media:YPAD | Treatment:ConcA Genotype:gem1 knockout | Media:YPAD | Treatment:DMSO Genotype:gem1 knockout | Media:YPAD | Treatment:DMSO Genotype:gem1 knockout | Media:YPAD | Treatment:DMSO Genotype:gem1 knockout | Media:YPAD | Treatment:DMSO Genotype:gem1 knockout | Media:YPAD | Treatment:Rap Genotype:gem1 knockout | Media:YPAD | Treatment:Rap Genotype:gem1 knockout | Media:YPAD | Treatment:Rap Genotype:gem1 knockout | Media:YPAD | Treatment:Rap Genotype:Pooled QC sample | Media:N/A | Treatment:N/A Genotype:Pooled QC sample | Media:N/A | Treatment:N/A Genotype:Pooled QC sample | Media:N/A | Treatment:N/A Genotype:Pooled QC sample | Media:N/A | Treatment:N/A Genotype:Process blank | Media:N/A | Treatment:N/A Genotype:Process blank | Media:N/A | Treatment:N/A Genotype:Process blank | Media:N/A | Treatment:N/A Genotype:Process blank | Media:N/A | Treatment:N/A Genotype:wild-type | Media:YPAD | Treatment:ConcA Genotype:wild-type | Media:YPAD | Treatment:ConcA Genotype:wild-type | Media:YPAD | Treatment:ConcA Genotype:wild-type | Media:YPAD | Treatment:ConcA Genotype:wild-type | Media:YPAD | Treatment:DMSO Genotype:wild-type | Media:YPAD | Treatment:DMSO Genotype:wild-type | Media:YPAD | Treatment:DMSO Genotype:wild-type | Media:YPAD | Treatment:DMSO Genotype:wild-type | Media:YPAD | Treatment:Rap Genotype:wild-type | Media:YPAD | Treatment:Rap Genotype:wild-type | Media:YPAD | Treatment:Rap Genotype:wild-type | Media:YPAD | Treatment:Rap 1_6-anhydro-Glucose 26173.0000 13453.0000 26729.0000 20206.0000 10910.0000 9871.0000 10780.0000 10413.0000 29413.0000 19583.0000 21749.0000 26349.0000 25178.0000 21887.0000 20473.0000 17293.0000 1813.0000 453.0000 1968.0000 36809.0000 28239.0000 30476.0000 23051.0000 13450.0000 9795.0000 10149.0000 9368.0000 24468.0000 33279.0000 18820.0000 21772.0000 1-Monomyristin 6402.0000 14255.0000 11511.0000 8072.0000 5073.0000 11485.0000 4710.0000 8156.0000 4635.0000 8336.0000 2061.0000 4126.0000 4140.0000 4296.0000 3619.0000 2238.0000 8849.0000 5847.0000 2799.0000 3719.0000 4425.0000 4703.0000 4216.0000 6237.0000 4492.0000 3552.0000 1-Octadecene 14419.0000 10757.0000 18197.0000 7618.0000 16857.0000 8740.0000 8416.0000 6338.0000 9308.0000 21759.0000 13280.0000 21664.0000 11448.0000 21529.0000 12067.0000 8479.0000 2778.0000 13647.0000 17812.0000 15300.0000 10376.0000 7054.0000 9818.0000 11818.0000 15549.0000 7716.0000 11286.0000 33228.0000 13412.0000 14771.0000 1-Palmitoylglycerol 164679.0000 143756.0000 152458.0000 116389.0000 161590.0000 169893.0000 171395.0000 131294.0000 160951.0000 122780.0000 147564.0000 192401.0000 169300.0000 218034.0000 93514.0000 152927.0000 89089.0000 224827.0000 244290.0000 133120.0000 130140.0000 142018.0000 161146.0000 153135.0000 143081.0000 148760.0000 252007.0000 166273.0000 165719.0000 1-Steroylglycerol 69488.0000 55509.0000 59916.0000 50185.0000 69314.0000 66454.0000 69380.0000 57104.0000 58818.0000 50838.0000 55857.0000 74451.0000 69013.0000 80904.0000 36040.0000 59567.0000 4132.0000 44801.0000 81024.0000 94748.0000 48341.0000 45111.0000 52954.0000 57159.0000 60660.0000 57478.0000 60466.0000 103396.0000 66543.0000 68981.0000 2-Hydroxybutyric acid 73655.0000 56297.0000 64584.0000 51975.0000 51503.0000 56812.0000 66784.0000 57915.0000 54146.0000 51394.0000 51537.0000 48436.0000 61599.0000 42890.0000 61497.0000 65685.0000 24028.0000 46923.0000 60750.0000 83525.0000 71325.0000 75990.0000 65599.0000 75108.0000 86808.0000 85016.0000 76709.0000 53986.0000 39831.0000 51024.0000 51749.0000 2-Hydroxyglutaric acid 12512.0000 20266.0000 12570.0000 9034.0000 18291.0000 20574.0000 19957.0000 16341.0000 6023.0000 6308.0000 6103.0000 5760.0000 17381.0000 18640.0000 15809.0000 16766.0000 533.0000 30272.0000 23124.0000 23779.0000 19680.0000 27531.0000 22520.0000 29313.0000 26484.0000 11047.0000 11155.0000 9161.0000 11278.0000 2-Ketoglutamic acid 1516.0000 1806.0000 427.0000 785.0000 2002.0000 1167.0000 1106.0000 698.0000 1410.0000 1333.0000 2264.0000 1568.0000 188.0000 2878.0000 1656.0000 2461.0000 323.0000 725.0000 1886.0000 364.0000 1294.0000 1610.0000 2-Ketoisocaproic acid 6981.0000 4066.0000 1761.0000 5728.0000 8812.0000 6382.0000 2596.0000 8288.0000 6030.0000 10004.0000 11501.0000 7301.0000 3463.0000 20097.0000 4564.0000 20317.0000 17315.0000 22619.0000 5711.0000 5491.0000 28723.0000 19098.0000 20329.0000 31984.0000 1728.0000 5802.0000 10988.0000 13217.0000 2-Monopalmitoylglycerol 10582.0000 12871.0000 8914.0000 7429.0000 11687.0000 11380.0000 13079.0000 10312.0000 12724.0000 8359.0000 8766.0000 14000.0000 15355.0000 14364.0000 4157.0000 10053.0000 651.0000 6038.0000 13490.0000 14134.0000 10569.0000 7519.0000 8659.0000 8317.0000 12932.0000 9077.0000 11444.0000 16959.0000 12694.0000 13016.0000 2-Steroylglycerol 783.0000 1482.0000 2612.0000 1302.0000 9058.0000 4002.0000 2966.0000 2783.0000 46353.0000 28441.0000 5643.0000 590.0000 3258.0000 3-Hydroxybutyrate 341.0000 159.0000 868.0000 721.0000 937.0000 247.0000 758.0000 1418.0000 605.0000 980.0000 3-Phosphoglyceric acid 1914.0000 695.0000 965.0000 2660.0000 567.0000 650.0000 3330.0000 1350.0000 2244.0000 1327.0000 3237.0000 2606.0000 3712.0000 710.0000 284.0000 113.0000 2161.0000 2862.0000 2956.0000 240.0000 4787.0000 166.0000 4-Hydroxyproline 1 235848.0000 221100.0000 301584.0000 273477.0000 282174.0000 227473.0000 216761.0000 216448.0000 167589.0000 205856.0000 187290.0000 189478.0000 232233.0000 273166.0000 273667.0000 194719.0000 3526.0000 180692.0000 266726.0000 291481.0000 248709.0000 203706.0000 280501.0000 261889.0000 236637.0000 179683.0000 211456.0000 195089.0000 166204.0000 197284.0000 4-Hydroxyproline 2 4657050.0000 3994681.0000 4160804.0000 4220471.0000 3876737.0000 3658548.0000 4138982.0000 3660405.0000 3806700.0000 3982702.0000 4068359.0000 3986138.0000 4479669.0000 5564426.0000 5171991.0000 4743325.0000 5117.0000 15097.0000 5120277.0000 4603655.0000 4482381.0000 4463822.0000 4105323.0000 3435370.0000 3808335.0000 3433852.0000 4546205.0000 4353650.0000 3512570.0000 4254490.0000 Adenine 283953.0000 77556.0000 282413.0000 230104.0000 63729.0000 67900.0000 81055.0000 61290.0000 231528.0000 241393.0000 176366.0000 194911.0000 216273.0000 215932.0000 144565.0000 200449.0000 623.0000 1510.0000 499128.0000 209420.0000 318530.0000 247606.0000 68634.0000 57182.0000 53929.0000 73713.0000 163635.0000 227969.0000 150626.0000 173650.0000 Adenosine 58377.0000 49335.0000 61401.0000 46511.0000 34328.0000 40398.0000 53294.0000 31573.0000 51652.0000 69394.0000 52729.0000 56978.0000 52890.0000 62062.0000 32572.0000 58427.0000 1334.0000 7782.0000 110875.0000 66407.0000 92623.0000 54940.0000 81763.0000 35863.0000 52066.0000 58479.0000 50543.0000 70622.0000 38547.0000 58293.0000 Adenosine monophosphate 599968.0000 618026.0000 520853.0000 297595.0000 372639.0000 489726.0000 420253.0000 404400.0000 244203.0000 303229.0000 105101.0000 298594.0000 180343.0000 72524.0000 851.0000 470508.0000 489.0000 630947.0000 546369.0000 518045.0000 309934.0000 482282.0000 439554.0000 475676.0000 507358.0000 333773.0000 459999.0000 366196.0000 324085.0000 Adipic acid 35667.0000 35669.0000 29437.0000 28294.0000 18107.0000 19988.0000 25828.0000 21566.0000 141140.0000 139326.0000 124988.0000 104584.0000 55655.0000 72417.0000 77501.0000 89125.0000 283.0000 184.0000 40923.0000 27450.0000 30077.0000 33385.0000 35416.0000 32143.0000 41535.0000 40242.0000 125536.0000 127165.0000 127828.0000 130752.0000 Allantoin 3674.0000 3309.0000 1097.0000 1522.0000 2887.0000 3384.0000 429.0000 584.0000 2888.0000 134.0000 2383.0000 2468.0000 2392.0000 1646.0000 380.0000 2319.0000 2437.0000 alpha-D-Glucosamine 1-phosphate 6679.0000 150.0000 727.0000 Arachidic acid 76655.0000 116636.0000 141063.0000 64265.0000 54582.0000 84568.0000 165635.0000 79812.0000 33155.0000 107687.0000 59101.0000 60514.0000 74538.0000 80584.0000 34974.0000 80281.0000 1559.0000 534.0000 12525.0000 100733.0000 63403.0000 74314.0000 84378.0000 62258.0000 60533.0000 95684.0000 52899.0000 56910.0000 146186.0000 60921.0000 63032.0000 Arachidonic Acid 1094.0000 1497.0000 648.0000 634.0000 925.0000 1433.0000 1512.0000 877.0000 1818.0000 343.0000 378.0000 1712.0000 368.0000 1847.0000 1927.0000 669.0000 Azelaic acid 5361.0000 16165.0000 4058.0000 3458.0000 11513.0000 12405.0000 7760.0000 18065.0000 14507.0000 16080.0000 10315.0000 12384.0000 11328.0000 11207.0000 10298.0000 12145.0000 4608.0000 4140.0000 3336.0000 6994.0000 30253.0000 20626.0000 10872.0000 24772.0000 18577.0000 21167.0000 14043.0000 12124.0000 Benzoic acid 126364.0000 96341.0000 104323.0000 109323.0000 111875.0000 90802.0000 121823.0000 83881.0000 79699.0000 86842.0000 106601.0000 94394.0000 137566.0000 112218.0000 100494.0000 97442.0000 4881.0000 71327.0000 121456.0000 117453.0000 105923.0000 120529.0000 110982.0000 112782.0000 124244.0000 96102.0000 103685.0000 108456.0000 78352.0000 95735.0000 Beta-Alanine 4216.0000 4459.0000 3257.0000 3274.0000 2911.0000 1932.0000 3386.0000 3832.0000 3494.0000 3809.0000 3145.0000 2266.0000 2174.0000 3174.0000 2610.0000 4315.0000 369.0000 1199.0000 4889.0000 2795.0000 2188.0000 6546.0000 4801.0000 3367.0000 4050.0000 5236.0000 3176.0000 4550.0000 3131.0000 Beta-Glycerophosphoric acid 25306.0000 34081.0000 24660.0000 18712.0000 16119.0000 19221.0000 21853.0000 17434.0000 18948.0000 11355.0000 8868.0000 11286.0000 10644.0000 14466.0000 8392.0000 9993.0000 854.0000 14716.0000 8008.0000 11631.0000 8286.0000 10820.0000 9618.0000 15444.0000 10989.0000 12636.0000 6583.0000 8110.0000 14310.0000 Capric acid 46655.0000 44079.0000 43242.0000 45595.0000 39603.0000 43756.0000 41847.0000 39354.0000 40589.0000 43722.0000 41034.0000 40125.0000 29711.0000 47597.0000 44150.0000 27052.0000 854.0000 21727.0000 34712.0000 43430.0000 46085.0000 36336.0000 38621.0000 33831.0000 38563.0000 31072.0000 40951.0000 37307.0000 40316.0000 40569.0000 Cellobiose 867013.0000 266324.0000 750110.0000 520847.0000 190533.0000 203406.0000 278119.0000 146828.0000 298800.0000 262234.0000 312834.0000 325138.0000 382059.0000 406001.0000 319475.0000 382638.0000 226.0000 3993.0000 228090.0000 1250125.0000 638581.0000 730913.0000 780436.0000 176626.0000 154767.0000 99388.0000 468031.0000 173669.0000 302715.0000 72555.0000 175891.0000 Cholesterol 393.0000 2958.0000 975.0000 1282.0000 618.0000 3363.0000 1208.0000 644.0000 2252.0000 1192.0000 1097.0000 cis-Aconitic acid 1393.0000 5257.0000 1609.0000 1058.0000 3038.0000 3533.0000 4539.0000 3190.0000 30431.0000 39526.0000 34458.0000 35811.0000 15620.0000 15299.0000 12167.0000 11565.0000 1647.0000 689.0000 8037.0000 3207.0000 3187.0000 2069.0000 35130.0000 47710.0000 41595.0000 47463.0000 Citric acid 274190.0000 410296.0000 266301.0000 199215.0000 321746.0000 383314.0000 421609.0000 311814.0000 2552613.0000 2643805.0000 2436719.0000 2615693.0000 1461539.0000 1404976.0000 1212558.0000 1320578.0000 907.0000 41784.0000 28001.0000 36471.0000 22629.0000 339725.0000 345710.0000 354398.0000 321503.0000 3040255.0000 3336379.0000 3207839.0000 3526968.0000 Creatinine 521.0000 1194.0000 160.0000 3659.0000 677.0000 3617.0000 489.0000 1179.0000 2663.0000 430.0000 2125.0000 1324.0000 1089.0000 1288.0000 Cystathionine 1377.0000 1790.0000 198.0000 993.0000 953.0000 3251.0000 484.0000 1156.0000 2460.0000 1174.0000 3069.0000 1794.0000 2179.0000 d4-succinate 715295.0000 637767.0000 660919.0000 616278.0000 553240.0000 602964.0000 724000.0000 589737.0000 615003.0000 656002.0000 522001.0000 563861.0000 643134.0000 695544.0000 607146.0000 618351.0000 1169.0000 4471.0000 520325.0000 769900.0000 614652.0000 679598.0000 684193.0000 698782.0000 562108.0000 657607.0000 562169.0000 597241.0000 584094.0000 476151.0000 570201.0000 D-Fructose 1 24115.0000 15264.0000 29400.0000 20264.0000 20604.0000 17883.0000 28035.0000 15233.0000 31976.0000 23809.0000 27425.0000 27066.0000 22940.0000 28669.0000 21052.0000 23455.0000 235.0000 244.0000 21594.0000 42572.0000 24440.0000 18018.0000 18097.0000 18134.0000 13811.0000 11344.0000 40417.0000 30577.0000 45112.0000 17903.0000 25310.0000 D-Fructose 2 2614.0000 4246.0000 3383.0000 4876.0000 5440.0000 4267.0000 4045.0000 5190.0000 5002.0000 3215.0000 59.0000 4458.0000 2310.0000 4378.0000 1458.0000 2268.0000 6468.0000 8666.0000 4692.0000 D-Galactose 1505165.0000 5142190.0000 1476455.0000 1194392.0000 3894009.0000 4102209.0000 4758039.0000 4168921.0000 8508753.0000 8257455.0000 7468437.0000 7763100.0000 5067397.0000 5573300.0000 5029732.0000 5032634.0000 7436.0000 413942.0000 150690.0000 228048.0000 181867.0000 3622820.0000 3293249.0000 3851967.0000 3188399.0000 7891657.0000 8076672.0000 7958231.0000 8188316.0000 D-Glucose 1 7391091.0000 4829906.0000 8447803.0000 4813359.0000 5181484.0000 5380047.0000 6318965.0000 4079532.0000 12948034.0000 11966427.0000 10582042.0000 14225703.0000 8611600.0000 9290871.0000 7580542.0000 8129760.0000 785.0000 17609924.0000 12658321.0000 6391950.0000 6517146.0000 4418744.0000 5388148.0000 4004092.0000 2116915.0000 13740795.0000 10326121.0000 15775666.0000 5168071.0000 10774423.0000 D-Glucose 2 999104.0000 626237.0000 1183835.0000 641376.0000 694899.0000 705950.0000 863425.0000 536184.0000 1778378.0000 1564950.0000 1399643.0000 2234632.0000 1128180.0000 1176080.0000 960556.0000 1023890.0000 163.0000 178.0000 3656275.0000 1794488.0000 842551.0000 858200.0000 578999.0000 686563.0000 521331.0000 267490.0000 2088207.0000 1375088.0000 2822339.0000 664930.0000 1381595.0000 D-Malic acid 1186796.0000 1268958.0000 1095819.0000 932046.0000 885003.0000 947393.0000 1172294.0000 924473.0000 423871.0000 457484.0000 365076.0000 328802.0000 822510.0000 906580.0000 788040.0000 807019.0000 436.0000 7289.0000 1591627.0000 1115159.0000 1424134.0000 1221126.0000 709370.0000 667327.0000 857806.0000 574601.0000 418661.0000 445103.0000 339821.0000 466264.0000 D-Mannose 18922.0000 7659.0000 15691.0000 4065.0000 7039.0000 9932.0000 11981.0000 11098.0000 34813.0000 41707.0000 33254.0000 34163.0000 21226.0000 6378.0000 13213.0000 492.0000 27091.0000 5636.0000 16251.0000 5237.0000 9919.0000 28853.0000 50721.0000 28356.0000 21917.0000 D-Ribose-5-phosphate 6007.0000 7585.0000 6950.0000 6790.0000 3553.0000 7115.0000 6944.0000 6671.0000 3354.0000 6188.0000 4285.0000 4339.0000 5740.0000 5625.0000 4497.0000 905.0000 461.0000 14667.0000 6270.0000 9834.0000 10869.0000 13161.0000 11160.0000 10970.0000 9288.0000 6578.0000 8993.0000 4356.0000 1750.0000 D-Threitol 413772.0000 114274.0000 367235.0000 355512.0000 91050.0000 91774.0000 112138.0000 96226.0000 73489.0000 84962.0000 65189.0000 67501.0000 189472.0000 209536.0000 177933.0000 183001.0000 565.0000 827.0000 9658.0000 604864.0000 427308.0000 466205.0000 442389.0000 94005.0000 78604.0000 83483.0000 77406.0000 72758.0000 69346.0000 56962.0000 70813.0000 Eicosane 10658.0000 14212.0000 19249.0000 23916.0000 34481.0000 17128.0000 28233.0000 5920.0000 20177.0000 42009.0000 25151.0000 39031.0000 18135.0000 26143.0000 17808.0000 16355.0000 19658.0000 24091.0000 26081.0000 17763.0000 9030.0000 11077.0000 12418.0000 19472.0000 16444.0000 24078.0000 34347.0000 13163.0000 11820.0000 Elaidic acid 30269.0000 34078.0000 14603.0000 12974.0000 11115.0000 16004.0000 21152.0000 37064.0000 15111.0000 14256.0000 38871.0000 7676.0000 22906.0000 40066.0000 24315.0000 18953.0000 4981.0000 27648.0000 22107.0000 8215.0000 24624.0000 10069.0000 16379.0000 Ergosterol 10148.0000 96801.0000 18624.0000 7267.0000 19708.0000 62341.0000 63266.0000 26507.0000 48638.0000 58767.0000 35627.0000 27397.0000 49718.0000 37570.0000 23291.0000 37287.0000 18055.0000 7610.0000 15039.0000 5674.0000 19616.0000 16352.0000 73188.0000 17319.0000 59903.0000 109578.0000 24425.0000 57595.0000 Ethanolamine 1 1237778.0000 1370277.0000 1134964.0000 1218293.0000 1196028.0000 1139437.0000 1147601.0000 1192255.0000 906934.0000 907614.0000 795210.0000 1264509.0000 906293.0000 602734.0000 423371.0000 988622.0000 1611.0000 1170176.0000 853366.0000 1089664.0000 1045803.0000 783923.0000 1026509.0000 927853.0000 1037871.0000 1135359.0000 1237328.0000 1230927.0000 1110034.0000 1141251.0000 Ethanolamine 2 1995502.0000 2299270.0000 1821965.0000 1656632.0000 2113970.0000 1809628.0000 2050563.0000 1803246.0000 3233717.0000 3420505.0000 3316192.0000 3318849.0000 1820431.0000 2427280.0000 2344101.0000 2444820.0000 592.0000 296.0000 1778506.0000 1853843.0000 1935843.0000 1564068.0000 1861199.0000 2172972.0000 2070545.0000 2330953.0000 2381317.0000 2423823.0000 2537358.0000 2167982.0000 2312076.0000 Fructose 1_6-diphosphate 5262.0000 2814.0000 1831.0000 3117.0000 3596.0000 3210.0000 2985.0000 3706.0000 3183.0000 2185.0000 1086.0000 2698.0000 2975.0000 3400.0000 3675.0000 1884.0000 2284.0000 2731.0000 3598.0000 1302.0000 4223.0000 Fructose 6-phosphate 3383.0000 2143.0000 2679.0000 3197.0000 2066.0000 5081.0000 2353.0000 2147.0000 4299.0000 790.0000 325.0000 2274.0000 2865.0000 2145.0000 4771.0000 8598.0000 4873.0000 5197.0000 Fumaric acid 274967.0000 292845.0000 267974.0000 227051.0000 240643.0000 242402.0000 287208.0000 234804.0000 119673.0000 116048.0000 98002.0000 94920.0000 222580.0000 210052.0000 190379.0000 195428.0000 597.0000 6797.0000 285681.0000 261621.0000 246864.0000 312807.0000 232586.0000 154888.0000 172830.0000 194578.0000 108872.0000 116619.0000 95715.0000 125253.0000 Galactonic acid 175.0000 726.0000 671.0000 305.0000 845.0000 364.0000 912.0000 1045.0000 Glucose 6-phosphate 13345.0000 9623.0000 17372.0000 12311.0000 8996.0000 12189.0000 12389.0000 10106.0000 18460.0000 21209.0000 15744.0000 19314.0000 15186.0000 19575.0000 16845.0000 16060.0000 664.0000 911.0000 13441.0000 32020.0000 13548.0000 14111.0000 14948.0000 10941.0000 8444.0000 6194.0000 18657.0000 23544.0000 40555.0000 23921.0000 25286.0000 Glutamic acid 2581.0000 1384.0000 1639.0000 1251.0000 1614.0000 1508.0000 1626.0000 2796.0000 2355.0000 2488.0000 2028.0000 895.0000 1682.0000 2215.0000 1406.0000 805.0000 1880.0000 3184.0000 1100.0000 2220.0000 788.0000 1843.0000 2404.0000 Glutamine 1187.0000 769.0000 1389.0000 202.0000 1033.0000 1667.0000 3701.0000 719.0000 437.0000 2490.0000 809.0000 4479.0000 2267.0000 2908.0000 1772.0000 2609.0000 1573.0000 1698.0000 Glutathione 23462.0000 60728.0000 29458.0000 25141.0000 25577.0000 31230.0000 23229.0000 23532.0000 3166.0000 18523.0000 4936.0000 17052.0000 14323.0000 3315.0000 3513.0000 15603.0000 133.0000 22792.0000 16793.0000 22101.0000 13367.0000 8238.0000 5432.0000 13063.0000 9466.0000 9081.0000 15588.0000 8568.0000 7436.0000 Glyceraldehyde 3-phosphate 580.0000 1095.0000 760.0000 2672.0000 1693.0000 783.0000 2005.0000 2465.0000 1907.0000 Glycerol 10031978.0000 7165946.0000 9325487.0000 9411290.0000 4498574.0000 5534630.0000 6237474.0000 5291252.0000 4880767.0000 5371920.0000 4730573.0000 5034773.0000 7093696.0000 8670884.0000 8079569.0000 8328515.0000 6120.0000 3414.0000 351151.0000 14115309.0000 11532694.0000 12817739.0000 11778024.0000 4944511.0000 5047678.0000 5262662.0000 5177419.0000 5240181.0000 5071543.0000 4220383.0000 5533563.0000 Glycerol 3-phosphate 26120.0000 35320.0000 24660.0000 18321.0000 16359.0000 19110.0000 23496.0000 19395.0000 22728.0000 12633.0000 12491.0000 12360.0000 11960.0000 15074.0000 10542.0000 12111.0000 275.0000 589.0000 251.0000 17276.0000 9958.0000 12271.0000 9667.0000 9557.0000 10237.0000 15942.0000 13025.0000 13596.0000 7830.0000 6901.0000 13885.0000 Glycine 2205293.0000 2376200.0000 1891350.0000 1862805.0000 1657132.0000 1756951.0000 2081093.0000 1786336.0000 2257492.0000 2503935.0000 1668861.0000 1598715.0000 1992997.0000 2179702.0000 1937800.0000 2017162.0000 76299.0000 2208800.0000 1619973.0000 1824542.0000 1745864.0000 2657089.0000 2302376.0000 2687161.0000 2402919.0000 1448571.0000 1015785.0000 834642.0000 1136541.0000 Glycolic acid 70114.0000 63506.0000 57330.0000 71552.0000 58335.0000 133450.0000 77765.0000 69682.0000 18362.0000 53427.0000 146230.0000 204918.0000 62876.0000 52906.0000 143919.0000 67412.0000 69708.0000 77641.0000 140132.0000 70697.0000 141317.0000 75430.0000 86340.0000 88511.0000 77083.0000 52664.0000 67648.0000 32990.0000 125290.0000 Glyoxylic acid 435112.0000 419496.0000 410923.0000 410929.0000 411536.0000 335881.0000 408223.0000 405831.0000 459381.0000 471819.0000 457335.0000 429870.0000 318783.0000 470889.0000 463982.0000 418337.0000 339.0000 433220.0000 457366.0000 472893.0000 456872.0000 423729.0000 471518.0000 436008.0000 450289.0000 474388.0000 437448.0000 432385.0000 419592.0000 407183.0000 Guanine 6151.0000 26412.0000 9359.0000 4516.0000 13155.0000 19045.0000 22821.0000 16759.0000 18412.0000 16607.0000 13386.0000 12182.0000 16756.0000 14521.0000 7032.0000 16249.0000 572.0000 790.0000 5546.0000 4762.0000 31373.0000 15199.0000 24369.0000 20876.0000 17366.0000 20517.0000 14868.0000 15207.0000 Heptadecanoic acid 588225.0000 773376.0000 833957.0000 536463.0000 444155.0000 626726.0000 1180566.0000 522738.0000 266758.0000 683955.0000 553863.0000 472089.0000 674647.0000 682851.0000 534843.0000 712965.0000 3363.0000 3579.0000 46598.0000 834391.0000 410993.0000 706984.0000 659223.0000 559103.0000 369056.0000 830713.0000 456647.0000 464594.0000 966403.0000 444053.0000 546505.0000 Heptanoic acid 8515.0000 6005.0000 6669.0000 7650.0000 8818.0000 6087.0000 8285.0000 10805.0000 7927.0000 10782.0000 4783.0000 4104.0000 5659.0000 5597.0000 9327.0000 4702.0000 7113.0000 7341.0000 3265.0000 5644.0000 8605.0000 5006.0000 8352.0000 8591.0000 8687.0000 7307.0000 12427.0000 6778.0000 Homoserine 1 Homoserine 2 1121.0000 324.0000 1753.0000 1013.0000 922.0000 1513.0000 362.0000 Hypoxanthine 59016.0000 100287.0000 60716.0000 46023.0000 60357.0000 76688.0000 106403.0000 74309.0000 310835.0000 372169.0000 272237.0000 331794.0000 169320.0000 155679.0000 120511.0000 160357.0000 2044.0000 45274.0000 11551.0000 35331.0000 20260.0000 102297.0000 73679.0000 101061.0000 93105.0000 500186.0000 578959.0000 491438.0000 633797.0000 Iminodiacetic acid 4363.0000 3286.0000 2817.0000 962.0000 16438.0000 5183.0000 5862.0000 12867.0000 7229.0000 11894.0000 3336.0000 1004.0000 4787.0000 9636.0000 3167.0000 3603.0000 6112.0000 12964.0000 18782.0000 10729.0000 15353.0000 Inosine 32215.0000 26490.0000 38579.0000 26684.0000 19348.0000 26401.0000 30880.0000 18810.0000 404676.0000 381592.0000 340367.0000 382112.0000 142476.0000 140114.0000 62701.0000 173568.0000 689.0000 790.0000 42494.0000 34862.0000 34688.0000 23051.0000 20129.0000 18863.0000 29579.0000 21556.0000 441984.0000 596657.0000 450093.0000 562182.0000 Inosine 5-monophosphate 2412.0000 4583.0000 2938.0000 976.0000 241.0000 688.0000 723.0000 1368.0000 1806.0000 300.0000 1750.0000 1530.0000 455.0000 Inositol phosphate 429693.0000 827068.0000 606587.0000 315293.0000 407434.0000 830481.0000 833958.0000 468026.0000 426570.0000 539641.0000 284418.0000 425266.0000 553702.0000 367413.0000 256699.0000 516724.0000 183.0000 4118.0000 708224.0000 268751.0000 445012.0000 320827.0000 490924.0000 495402.0000 500346.0000 348520.0000 487518.0000 767880.0000 422822.0000 435584.0000 Isocitric acid 83970.0000 149205.0000 86541.0000 63421.0000 101491.0000 123742.0000 166544.0000 99085.0000 865022.0000 997900.0000 922983.0000 868925.0000 419864.0000 466120.0000 421455.0000 437182.0000 295.0000 373.0000 22830.0000 12207.0000 15733.0000 11247.0000 119769.0000 113363.0000 133711.0000 87989.0000 948637.0000 1131404.0000 882508.0000 1066911.0000 Itaconic acid 435246.0000 422769.0000 385126.0000 412305.0000 411209.0000 335421.0000 407171.0000 391408.0000 456073.0000 440261.0000 457108.0000 429272.0000 311456.0000 473933.0000 449872.0000 417030.0000 429412.0000 457366.0000 471873.0000 455642.0000 420416.0000 486754.0000 441048.0000 450837.0000 474569.0000 450201.0000 430398.0000 419115.0000 424121.0000 L-Alanine 2889987.0000 2672381.0000 2650890.0000 2427876.0000 2108514.0000 2020482.0000 2661340.0000 1974939.0000 10264126.0000 11328895.0000 9238869.0000 9296604.0000 4543581.0000 5039122.0000 4836377.0000 5490942.0000 1717.0000 222534.0000 1679622.0000 994731.0000 1290986.0000 1004618.0000 2059117.0000 1928755.0000 2383315.0000 2199842.0000 7737955.0000 8755219.0000 7607207.0000 9002662.0000 Lanosterol 532.0000 342.0000 815.0000 703.0000 595.0000 350.0000 1190.0000 797.0000 364.0000 779.0000 303.0000 406.0000 1355.0000 L-Ascorbic acid 3039.0000 2104.0000 3524.0000 2313.0000 3081.0000 3354.0000 3246.0000 2073.0000 7924.0000 5330.0000 595.0000 8316.0000 3425.0000 4140.0000 2840.0000 3135.0000 461.0000 6773.0000 5578.0000 3827.0000 2811.0000 760.0000 2887.0000 2363.0000 638.0000 502.0000 5185.0000 12998.0000 3829.0000 6547.0000 L-Asparagine 175882.0000 208070.0000 160297.0000 127295.0000 143001.0000 168436.0000 274780.0000 150892.0000 1614154.0000 1036570.0000 961074.0000 719874.0000 371745.0000 462766.0000 338230.0000 230553.0000 920.0000 319.0000 142612.0000 87717.0000 115770.0000 104958.0000 186561.0000 128939.0000 139153.0000 128492.0000 1363324.0000 1793033.0000 1913007.0000 2204975.0000 L-Aspartic acid 1 924272.0000 721511.0000 836419.0000 798421.0000 629156.0000 643791.0000 776317.0000 626360.0000 948469.0000 1022667.0000 862465.0000 783863.0000 735822.0000 839352.0000 758798.0000 736046.0000 1245.0000 128.0000 5522.0000 550320.0000 368397.0000 429069.0000 379331.0000 556645.0000 481714.0000 573876.0000 481064.0000 859048.0000 749704.0000 602280.0000 771836.0000 L-Aspartic acid 2 16287553.0000 9199188.0000 15235714.0000 14264817.0000 4831548.0000 8002945.0000 8634770.0000 5921368.0000 14719804.0000 19924429.0000 16679764.0000 14611981.0000 9594383.0000 9323025.0000 7516114.0000 9926489.0000 5033.0000 11006874.0000 5743969.0000 6719730.0000 8109140.0000 6325198.0000 5866443.0000 8056492.0000 5951045.0000 15592901.0000 19202776.0000 16237766.0000 17219905.0000 Lauric Acid 156306.0000 145019.0000 148865.0000 129798.0000 127874.0000 134896.0000 158724.0000 122570.0000 70802.0000 88642.0000 76954.0000 87977.0000 110078.0000 119101.0000 110717.0000 123945.0000 677.0000 1745.0000 7986.0000 132638.0000 119245.0000 130607.0000 118008.0000 113597.0000 99894.0000 147191.0000 113546.0000 92791.0000 102013.0000 70926.0000 103888.0000 L-Glutamic acid 21656583.0000 19945090.0000 21506803.0000 20679232.0000 17591644.0000 19310417.0000 19947333.0000 18545874.0000 24224564.0000 23844089.0000 23469696.0000 22618872.0000 21638148.0000 22085711.0000 20641697.0000 21917643.0000 395.0000 811.0000 4133.0000 21971796.0000 20378460.0000 20514077.0000 21399920.0000 18993460.0000 18598715.0000 19527323.0000 18665536.0000 24651932.0000 32022033.0000 32084659.0000 36199567.0000 L-Gulonic acid gamma-lactone 832.0000 1705.0000 1653.0000 1179.0000 880.0000 1643.0000 1927.0000 2441.0000 2971.0000 3960.0000 2684.0000 2087.0000 2797.0000 1910.0000 172.0000 360.0000 1217.0000 1347.0000 919.0000 1078.0000 940.0000 1790.0000 2735.0000 1609.0000 2717.0000 3700.0000 Linoleic acid 2498.0000 1561.0000 942.0000 362.0000 1064.0000 1053.0000 1964.0000 1168.0000 443.0000 459.0000 1639.0000 1641.0000 1002.0000 1776.0000 L-Isoleucine 1 3606389.0000 3501833.0000 2934035.0000 2918092.0000 2408930.0000 2350758.0000 3135287.0000 2456774.0000 10605681.0000 11795032.0000 8983250.0000 9231095.0000 5007033.0000 5796686.0000 5335056.0000 5297154.0000 14030.0000 513169.0000 3523430.0000 2269521.0000 2451540.0000 2295715.0000 4329136.0000 3209166.0000 3981646.0000 4303301.0000 9646579.0000 10066399.0000 7774213.0000 10403405.0000 L-Isoleucine 2 4914220.0000 3600037.0000 4087218.0000 4110385.0000 2864075.0000 2841648.0000 3824012.0000 2611815.0000 7566170.0000 10101285.0000 6585420.0000 6847626.0000 5141632.0000 5720993.0000 5232881.0000 6203450.0000 472.0000 3434.0000 310869.0000 5309192.0000 3792173.0000 4118889.0000 3633401.0000 4856184.0000 4637874.0000 5096656.0000 5424645.0000 7746863.0000 8426820.0000 6461255.0000 7756793.0000 L-Lactic acid 112206.0000 107650.0000 108319.0000 118064.0000 103700.0000 93619.0000 118587.0000 88654.0000 99214.0000 98542.0000 104653.0000 107331.0000 109168.0000 111464.0000 101345.0000 97363.0000 761.0000 17075.0000 81521.0000 130252.0000 111363.0000 116560.0000 100523.0000 103185.0000 96356.0000 86865.0000 126696.0000 105159.0000 119280.0000 87414.0000 114377.0000 L-Leucine 1 277530.0000 276131.0000 249888.0000 241564.0000 198506.0000 202121.0000 254990.0000 211081.0000 786037.0000 878796.0000 659939.0000 682016.0000 368666.0000 425829.0000 367676.0000 364935.0000 54188.0000 237969.0000 152857.0000 163661.0000 148794.0000 311053.0000 249927.0000 278598.0000 319286.0000 583395.0000 653736.0000 496334.0000 629647.0000 L-Leucine 2 88923.0000 76369.0000 77102.0000 84109.0000 65962.0000 62002.0000 77526.0000 58593.0000 167706.0000 208782.0000 161868.0000 162151.0000 89027.0000 103830.0000 98367.0000 112845.0000 158.0000 6888.0000 76676.0000 57699.0000 59236.0000 47951.0000 92473.0000 87740.0000 99086.0000 119048.0000 145728.0000 176484.0000 137894.0000 138596.0000 L-Lysine 11051822.0000 20584333.0000 10890882.0000 8416058.0000 18340408.0000 18663035.0000 20051779.0000 18641598.0000 24682280.0000 24688500.0000 23763944.0000 24367972.0000 20872895.0000 20750854.0000 19971430.0000 19985709.0000 872.0000 1116.0000 3087213.0000 1111384.0000 1674056.0000 1363341.0000 18061497.0000 17286455.0000 18602718.0000 17433627.0000 23854564.0000 24251332.0000 23695040.0000 24248537.0000 L-Methionine 1 231729.0000 349463.0000 206829.0000 198058.0000 309758.0000 299881.0000 378056.0000 296971.0000 471521.0000 574592.0000 439310.0000 462024.0000 404278.0000 454640.0000 424591.0000 393041.0000 403.0000 335.0000 16113.0000 138041.0000 97676.0000 101518.0000 99522.0000 350118.0000 241889.0000 356532.0000 330400.0000 663290.0000 832613.0000 715370.0000 771872.0000 L-Methionine 2 530252.0000 339193.0000 462320.0000 351216.0000 205387.0000 289782.0000 312830.0000 242351.0000 787377.0000 780107.0000 490227.0000 546021.0000 425518.0000 440426.0000 364011.0000 416616.0000 317.0000 3794.0000 2928.0000 306219.0000 170485.0000 176146.0000 146572.0000 294029.0000 232134.0000 385601.0000 297944.0000 758140.0000 1027967.0000 1078575.0000 1123353.0000 L-Phenylalanine 1 2314826.0000 3059776.0000 2123185.0000 2067727.0000 2566511.0000 2365790.0000 3181210.0000 2546434.0000 6790056.0000 8447726.0000 6411456.0000 6728401.0000 4441333.0000 5122602.0000 4483622.0000 4165253.0000 2077859.0000 1365298.0000 1484606.0000 1260847.0000 3412679.0000 2704950.0000 3153437.0000 3458907.0000 5671463.0000 6461513.0000 4726406.0000 5953067.0000 L-Phenylalanine 2 1330000.0000 1102449.0000 1144995.0000 908403.0000 629648.0000 849717.0000 1052247.0000 751237.0000 7261645.0000 7348399.0000 4685269.0000 5085388.0000 2013541.0000 1955692.0000 1543283.0000 1998660.0000 11611.0000 32703.0000 880363.0000 527158.0000 596523.0000 599271.0000 1094905.0000 945364.0000 1234276.0000 1158849.0000 4937759.0000 7074030.0000 6096336.0000 6860533.0000 L-Proline 1 7113871.0000 4894016.0000 5873676.0000 5559295.0000 4230348.0000 4514100.0000 5217516.0000 3687938.0000 6881654.0000 6746416.0000 5813714.0000 6182501.0000 5613231.0000 6428020.0000 5526051.0000 4916605.0000 16385.0000 48839.0000 31406.0000 6064879.0000 3872729.0000 4355499.0000 4042839.0000 4337735.0000 3423622.0000 4150951.0000 3723336.0000 7873192.0000 9423733.0000 6962729.0000 9068309.0000 L-Proline 2 5721350.0000 3087104.0000 4630741.0000 4298212.0000 2358070.0000 2594949.0000 3588522.0000 2469306.0000 2580458.0000 2924366.0000 2099105.0000 2113986.0000 2864178.0000 3453997.0000 2729578.0000 3437620.0000 2405.0000 3873.0000 19223.0000 5475860.0000 3088323.0000 4335226.0000 3735697.0000 2823801.0000 2723750.0000 2333122.0000 3231849.0000 3338578.0000 4270541.0000 3149018.0000 3383082.0000 L-Serine 1 10056318.0000 9528168.0000 8952096.0000 8236279.0000 7096494.0000 6891395.0000 8856718.0000 7262763.0000 4844357.0000 6233277.0000 4700742.0000 4327022.0000 5200386.0000 6218673.0000 5433004.0000 5565958.0000 16695.0000 18231.0000 278503.0000 4168716.0000 2782095.0000 2986569.0000 2746821.0000 8091715.0000 6963079.0000 8447435.0000 7326429.0000 1857104.0000 1609281.0000 1053984.0000 1436529.0000 L-Serine 2 4107933.0000 2701416.0000 3472795.0000 2882833.0000 1608567.0000 2197996.0000 2566233.0000 1924490.0000 2312893.0000 2722243.0000 1797752.0000 1833784.0000 2045792.0000 2060569.0000 1796247.0000 2242816.0000 184.0000 4006.0000 35914.0000 1973946.0000 911249.0000 877779.0000 1250454.0000 2958880.0000 2467316.0000 3370675.0000 2433351.0000 582925.0000 572200.0000 414440.0000 585985.0000 L-Sorbose 450377.0000 297015.0000 519577.0000 303730.0000 331476.0000 335623.0000 399579.0000 252131.0000 780832.0000 728724.0000 657085.0000 966201.0000 537904.0000 562840.0000 472368.0000 506254.0000 368.0000 1321625.0000 799093.0000 376466.0000 395985.0000 272149.0000 332276.0000 249615.0000 133137.0000 897469.0000 636201.0000 1124728.0000 324027.0000 659064.0000 L-Threonine 1 6388951.0000 5665323.0000 5525173.0000 5517776.0000 4068130.0000 3987250.0000 5081894.0000 4185658.0000 6089086.0000 6684275.0000 4975408.0000 5227643.0000 5404855.0000 6527778.0000 5760014.0000 6081223.0000 129662.0000 6849028.0000 5036969.0000 5534396.0000 5161373.0000 8424371.0000 7172855.0000 7934928.0000 7097582.0000 5331902.0000 5016311.0000 4320525.0000 5274337.0000 L-Threonine 2 1330997.0000 874540.0000 1112028.0000 975552.0000 507037.0000 647129.0000 762162.0000 580084.0000 1057828.0000 1181098.0000 783950.0000 850975.0000 960954.0000 1019535.0000 835084.0000 1008565.0000 204.0000 972.0000 6895.0000 1508644.0000 945254.0000 896927.0000 1067876.0000 1242632.0000 1107524.0000 1457276.0000 1056585.0000 737104.0000 801526.0000 663379.0000 777270.0000 L-Tyrosine 1 175874.0000 357229.0000 170435.0000 142228.0000 190830.0000 272601.0000 256195.0000 257819.0000 1056742.0000 1245372.0000 929515.0000 846847.0000 547297.0000 595605.0000 360215.0000 450018.0000 85148.0000 175504.0000 149800.0000 112954.0000 119977.0000 196911.0000 202880.0000 283456.0000 248521.0000 853372.0000 1005731.0000 700081.0000 883228.0000 L-Tyrosine 2 71868.0000 108192.0000 71721.0000 54546.0000 79260.0000 78540.0000 101501.0000 80749.0000 832916.0000 884216.0000 628635.0000 658428.0000 234256.0000 240697.0000 210867.0000 237196.0000 436.0000 434.0000 38147.0000 19253.0000 27774.0000 21619.0000 106433.0000 81713.0000 106728.0000 100800.0000 631562.0000 683777.0000 576924.0000 717764.0000 L-Valine 1 3319046.0000 5193657.0000 2933730.0000 2851494.0000 3831015.0000 3426453.0000 4030271.0000 3333526.0000 12793791.0000 13937111.0000 11921286.0000 11134046.0000 6938237.0000 7745546.0000 7330406.0000 7544298.0000 108331.0000 288790.0000 680154.0000 4012325.0000 2769724.0000 3079203.0000 2493526.0000 6186715.0000 4350627.0000 5594007.0000 6136010.0000 12937978.0000 12703628.0000 12013100.0000 13627411.0000 L-Valine 2 4645355.0000 6266085.0000 4202663.0000 3838557.0000 3975248.0000 4331827.0000 5602507.0000 3901092.0000 13101212.0000 13691141.0000 11163779.0000 11828472.0000 7750257.0000 8413030.0000 7564764.0000 7801861.0000 2903.0000 827483.0000 6006824.0000 3959928.0000 4187721.0000 3745326.0000 6551044.0000 5769187.0000 7243490.0000 7309491.0000 12640993.0000 13712020.0000 11334245.0000 12641601.0000 Malonic acid 5551.0000 335.0000 3214.0000 4158.0000 3433.0000 2474.0000 5408.0000 3329.0000 4197.0000 3802.0000 5284.0000 523.0000 3019.0000 4413.0000 3930.0000 3706.0000 737.0000 149.0000 3898.0000 4958.0000 3339.0000 5195.0000 3761.0000 5042.0000 3401.0000 6926.0000 5546.0000 3700.0000 342.0000 3460.0000 3618.0000 methyl-beta-D-Galactopyranoside 23578.0000 65779.0000 24966.0000 9898.0000 46018.0000 54698.0000 52463.0000 46740.0000 64467.0000 73974.0000 51185.0000 58199.0000 45273.0000 47887.0000 27422.0000 32380.0000 17347.0000 6537.0000 10517.0000 19154.0000 20990.0000 30483.0000 20837.0000 45336.0000 74180.0000 43958.0000 53047.0000 Methylmalonic acid 40308.0000 32666.0000 37281.0000 35520.0000 28210.0000 25121.0000 43196.0000 31839.0000 14554.0000 36457.0000 34768.0000 35746.0000 37359.0000 35491.0000 35710.0000 33767.0000 285.0000 869.0000 10264.0000 30536.0000 30046.0000 38239.0000 32332.0000 28491.0000 24652.0000 41534.0000 30172.0000 29053.0000 33930.0000 28007.0000 33672.0000 Myoinositol 2933682.0000 2803024.0000 3006338.0000 2320017.0000 2004754.0000 2299179.0000 2862575.0000 2035171.0000 2723301.0000 3271705.0000 2108222.0000 2016745.0000 2309898.0000 2439690.0000 2060965.0000 2178121.0000 325.0000 55251.0000 2667066.0000 2103142.0000 2231699.0000 2043334.0000 1478826.0000 1313790.0000 1715185.0000 1380879.0000 1596061.0000 2016795.0000 1723757.0000 1986796.0000 Myristic acid 1273693.0000 1233514.0000 1388062.0000 1167326.0000 2049734.0000 1041855.0000 1645420.0000 1132823.0000 771183.0000 2581752.0000 1130373.0000 2306540.0000 1371692.0000 2373610.0000 1073046.0000 1237157.0000 1144.0000 626311.0000 2059868.0000 1817276.0000 1165231.0000 1053004.0000 1054826.0000 809395.0000 1275885.0000 971164.0000 1201930.0000 2934703.0000 996258.0000 1370390.0000 Myristic Acid d27 6956.0000 1397.0000 3149.0000 4826.0000 5076.0000 2448.0000 828.0000 3820.0000 1621.0000 1671.0000 3348.0000 2086.0000 2225.0000 1085.0000 907.0000 6312.0000 N-acetyl-L-aspartic acid 1395.0000 632.0000 181.0000 790.0000 347.0000 530.0000 1071.0000 1044.0000 1568.0000 96.0000 266.0000 427.0000 321.0000 516.0000 416.0000 N-acetyl-Lysine 56571.0000 566572.0000 59798.0000 57303.0000 353371.0000 444097.0000 413232.0000 390615.0000 583046.0000 723078.0000 514163.0000 452980.0000 341328.0000 366829.0000 229857.0000 305704.0000 24338.0000 24492.0000 17670.0000 18202.0000 218446.0000 187526.0000 283259.0000 162394.0000 493275.0000 707507.0000 411756.0000 513811.0000 Nicotinamide 519291.0000 640756.0000 530394.0000 449148.0000 484324.0000 506263.0000 615849.0000 493268.0000 375994.0000 444698.0000 372112.0000 378901.0000 523858.0000 644049.0000 579518.0000 595662.0000 477.0000 655526.0000 367999.0000 534493.0000 387520.0000 394300.0000 406812.0000 592766.0000 480039.0000 418224.0000 592421.0000 415442.0000 371164.0000 Nitrous Oxide 1989418.0000 2986023.0000 2084457.0000 2067184.0000 2742466.0000 3120899.0000 2812010.0000 2133918.0000 1269350.0000 1501576.0000 1560715.0000 1674156.0000 2453574.0000 2247004.0000 2155952.0000 2118741.0000 987.0000 1838514.0000 2189556.0000 2137323.0000 1840744.0000 2177776.0000 2593306.0000 2338406.0000 2572133.0000 2394319.0000 2350267.0000 1772682.0000 1689470.0000 1964963.0000 Nonanoic acid 616561.0000 437263.0000 444801.0000 590694.0000 542027.0000 438148.0000 545780.0000 460229.0000 569953.0000 453316.0000 555657.0000 588214.0000 525728.0000 757163.0000 491712.0000 484715.0000 414.0000 993.0000 335039.0000 629595.0000 730467.0000 419377.0000 463917.0000 533175.0000 479981.0000 506135.0000 457963.0000 544730.0000 718690.0000 462742.0000 516273.0000 Oleic acid 73127.0000 126365.0000 79642.0000 54093.0000 128305.0000 131757.0000 83413.0000 68394.0000 50523.0000 119976.0000 68896.0000 76605.0000 37260.0000 92401.0000 36012.0000 63302.0000 396.0000 2680.0000 72508.0000 74924.0000 62368.0000 31922.0000 65716.0000 48235.0000 69746.0000 87163.0000 148270.0000 148344.0000 72546.0000 130633.0000 O-Phosphoethanolamine 3337.0000 1909.0000 1242.0000 2359.0000 1665.0000 2065.0000 1312.0000 3322.0000 1967.0000 1298.0000 3963.0000 2597.0000 1145.0000 1034.0000 883.0000 2981.0000 1261.0000 1955.0000 640.0000 2870.0000 1227.0000 2802.0000 2328.0000 Ornithine 47178.0000 176953.0000 37269.0000 47830.0000 122997.0000 123658.0000 367050.0000 180152.0000 1352365.0000 1425441.0000 1328393.0000 1172995.0000 678952.0000 542195.0000 586438.0000 380933.0000 1011.0000 1407.0000 704.0000 16958.0000 2868.0000 11343.0000 8316.0000 235904.0000 153040.0000 137419.0000 109679.0000 1499547.0000 1725940.0000 1507998.0000 1581522.0000 Orotic acid 164148.0000 202523.0000 166025.0000 120374.0000 94650.0000 124764.0000 146894.0000 119498.0000 135217.0000 79599.0000 64494.0000 69084.0000 84110.0000 94028.0000 58173.0000 96354.0000 983.0000 111290.0000 56277.0000 72769.0000 59413.0000 75298.0000 65876.0000 97549.0000 79694.0000 83544.0000 68949.0000 48591.0000 120003.0000 Oxalic acid 243550.0000 169544.0000 312842.0000 139448.0000 159395.0000 166524.0000 259742.0000 223439.0000 205688.0000 183988.0000 198391.0000 197115.0000 223197.0000 401347.0000 163728.0000 187860.0000 1611.0000 397.0000 310074.0000 241826.0000 207356.0000 180873.0000 292456.0000 170389.0000 257682.0000 441185.0000 224146.0000 135909.0000 128073.0000 170928.0000 171122.0000 Palmitic acid 11463788.0000 14032065.0000 14257934.0000 10311871.0000 10169238.0000 12570136.0000 16271732.0000 11104242.0000 5245157.0000 13628948.0000 10848273.0000 10733644.0000 12731935.0000 13664304.0000 11142161.0000 13165601.0000 1049314.0000 14706210.0000 9259007.0000 13340160.0000 12610115.0000 11229813.0000 8360682.0000 14733638.0000 9799466.0000 9781395.0000 15407206.0000 9084085.0000 11064660.0000 Palmitoleic acid 292814.0000 420572.0000 360112.0000 221679.0000 386575.0000 391661.0000 319987.0000 279793.0000 368669.0000 308311.0000 368905.0000 275678.0000 90238.0000 351799.0000 221785.0000 295821.0000 71621.0000 379668.0000 194675.0000 230082.0000 231534.0000 286473.0000 304296.0000 457528.0000 302986.0000 369760.0000 372920.0000 343545.0000 423002.0000 Phosphate 14804300.0000 16112694.0000 14273831.0000 13815409.0000 13422326.0000 13977532.0000 14451814.0000 13650341.0000 16571996.0000 16805053.0000 16065995.0000 16334815.0000 13667368.0000 15948017.0000 15390367.0000 15041357.0000 1546.0000 305997.0000 14741666.0000 12774672.0000 13798653.0000 12493331.0000 15771066.0000 15198992.0000 16438400.0000 14691494.0000 16017205.0000 16873973.0000 16020994.0000 16054333.0000 Phosphatidyl Glycerol 640.0000 1359.0000 397.0000 1488.0000 612.0000 469.0000 135.0000 917.0000 439.0000 2103.0000 Phosphoenolpyruvate 9010.0000 42478.0000 5421.0000 8634.0000 39117.0000 37235.0000 24738.0000 46355.0000 46024.0000 47158.0000 31427.0000 37446.0000 31809.0000 32023.0000 25278.0000 30514.0000 843.0000 7714.0000 8451.0000 3648.0000 10436.0000 67160.0000 35875.0000 20102.0000 53942.0000 55055.0000 49053.0000 43181.0000 46208.0000 Putrescine 249395.0000 89142.0000 389841.0000 222074.0000 85918.0000 121583.0000 152141.0000 83598.0000 474389.0000 551857.0000 345467.0000 346812.0000 250844.0000 282134.0000 215561.0000 272619.0000 18666.0000 225202.0000 78793.0000 151724.0000 108254.0000 57011.0000 72348.0000 119799.0000 71989.0000 380164.0000 352824.0000 253379.0000 295355.0000 Pyroglutamic acid 205586.0000 128838.0000 184131.0000 171168.0000 84089.0000 96500.0000 107611.0000 91593.0000 1147511.0000 1052252.0000 918038.0000 841648.0000 382136.0000 584116.0000 555131.0000 584750.0000 1350.0000 2023.0000 272359.0000 193369.0000 203232.0000 206431.0000 137104.0000 117309.0000 139436.0000 121344.0000 964064.0000 1051738.0000 1090120.0000 1078850.0000 Pyrophosphate 1061513.0000 2032115.0000 609705.0000 682613.0000 1191697.0000 1637736.0000 705679.0000 1571972.0000 1239810.0000 2256252.0000 607772.0000 3250301.0000 505262.0000 192497.0000 159136.0000 1852322.0000 859.0000 193.0000 547.0000 148668.0000 238279.0000 198375.0000 47405.0000 477933.0000 1073022.0000 1435632.0000 1034262.0000 1439427.0000 2101199.0000 977949.0000 319250.0000 Pyrrolidonecarboxylic acid 148261.0000 111110.0000 134923.0000 166334.0000 91649.0000 86152.0000 110696.0000 80643.0000 631795.0000 793772.0000 597520.0000 668140.0000 243875.0000 414778.0000 332305.0000 344769.0000 248.0000 639.0000 266173.0000 194208.0000 178071.0000 152680.0000 104856.0000 80324.0000 110635.0000 89160.0000 698662.0000 717579.0000 588304.0000 682747.0000 Pyruvic acid 247314.0000 302267.0000 201101.0000 173272.0000 269907.0000 274768.0000 296167.0000 246230.0000 823809.0000 719278.0000 579230.0000 616565.0000 526231.0000 572064.0000 541988.0000 559691.0000 52437.0000 48044.0000 232695.0000 119222.0000 122624.0000 145648.0000 248199.0000 216256.0000 245005.0000 222460.0000 590952.0000 627550.0000 577181.0000 620496.0000 Ribitol 143463.0000 45127.0000 131957.0000 119092.0000 40089.0000 40855.0000 52123.0000 40236.0000 43776.0000 48346.0000 44182.0000 42618.0000 72278.0000 76905.0000 63599.0000 70438.0000 1333.0000 4741.0000 153286.0000 119044.0000 127991.0000 119361.0000 29694.0000 26056.0000 31711.0000 22650.0000 51472.0000 52948.0000 45339.0000 58433.0000 Ribonic acid-gamma-lactone 406.0000 315.0000 597.0000 131.0000 1405.0000 2629.0000 2707.0000 3224.0000 1729.0000 1143.0000 639.0000 414.0000 453.0000 148.0000 3409.0000 3659.0000 3890.0000 4569.0000 Sedoheptulose 7-phosphate 5715.0000 11732.0000 6933.0000 5762.0000 8849.0000 11374.0000 10233.0000 10131.0000 6334.0000 6765.0000 4954.0000 5290.0000 6279.0000 6409.0000 5145.0000 7960.0000 359.0000 262.0000 6604.0000 3783.0000 4085.0000 3694.0000 5458.0000 4754.0000 6132.0000 7121.0000 6917.0000 6798.0000 5816.0000 4589.0000 Sophorose 1587.0000 2680.0000 413.0000 663.0000 904.0000 437.0000 1169.0000 1731.0000 1033.0000 739.0000 4483.0000 1294.0000 2556.0000 3095.0000 692.0000 3686.0000 1935.0000 1256.0000 Sorbitol 1375885.0000 248102.0000 1271086.0000 1124927.0000 176190.0000 229464.0000 307252.0000 202332.0000 269848.0000 292184.0000 259232.0000 227817.0000 681869.0000 683812.0000 596504.0000 607582.0000 7009.0000 1954273.0000 1124774.0000 1322265.0000 1088209.0000 195065.0000 162794.0000 197938.0000 172159.0000 313536.0000 294424.0000 245830.0000 318118.0000 Stearic acid 16197508.0000 18339310.0000 19391441.0000 15868203.0000 13036048.0000 16749010.0000 20382726.0000 15163902.0000 7781014.0000 17758150.0000 15346596.0000 15271776.0000 17926672.0000 18100784.0000 15075775.0000 17641064.0000 787702.0000 19121927.0000 12100226.0000 17338880.0000 17978232.0000 15885451.0000 11886939.0000 19407118.0000 12901329.0000 14256772.0000 19327247.0000 13418925.0000 15454349.0000 Succinic acid 334469.0000 656601.0000 280918.0000 272300.0000 311832.0000 354791.0000 419152.0000 353753.0000 166386.0000 175861.0000 140512.0000 144386.0000 514927.0000 535610.0000 466312.0000 492942.0000 104.0000 50121.0000 1352494.0000 1014970.0000 1078666.0000 987463.0000 1383585.0000 1185055.0000 1391891.0000 1245855.0000 156466.0000 172850.0000 102575.0000 156499.0000 Sucrose 1191.0000 1048.0000 1253.0000 708.0000 918.0000 880.0000 641.0000 539.0000 1215.0000 1660.0000 411.0000 1907.0000 971.0000 1887.0000 2137.0000 876.0000 840.0000 Taurine 5528.0000 8152.0000 4831.0000 5177.0000 4740.0000 6292.0000 4932.0000 6894.0000 10479.0000 10449.0000 9056.0000 11228.0000 5648.0000 6934.0000 8824.0000 8405.0000 242.0000 3517.0000 7867.0000 7695.0000 9260.0000 10484.0000 6961.0000 7017.0000 9358.0000 9018.0000 8912.0000 7342.0000 9484.0000 10500.0000 Threonic acid 7588.0000 5495.0000 5934.0000 5887.0000 3511.0000 3730.0000 6205.0000 4260.0000 4342.0000 4463.0000 7141.0000 3022.0000 4499.0000 4428.0000 5386.0000 3823.0000 1921.0000 11182.0000 8384.0000 7501.0000 6686.0000 6059.0000 5424.0000 5725.0000 5835.0000 2947.0000 5695.0000 4413.0000 3908.0000 Thymine 10267.0000 11612.0000 9096.0000 10546.0000 4167.0000 3542.0000 3919.0000 6664.0000 6187.0000 11097.0000 6598.0000 9704.0000 3494.0000 9244.0000 8766.0000 6254.0000 3735.0000 5255.0000 5244.0000 7939.0000 6533.0000 7858.0000 4007.0000 5587.0000 6123.0000 9115.0000 8361.0000 9346.0000 11473.0000 Trehalose 5018.0000 6335.0000 5269.0000 5392.0000 6571.0000 6554.0000 2708.0000 6779.0000 5566.0000 4087.0000 8935.0000 10119.0000 3526.0000 Turanose 11802.0000 4693.0000 7702.0000 6847.0000 5196.0000 3881.0000 6032.0000 3802.0000 7906.0000 7748.0000 5748.0000 6774.0000 6820.0000 6651.0000 6931.0000 6272.0000 255.0000 2038.0000 10000.0000 2060.0000 4246.0000 7853.0000 6866.0000 7049.0000 3607.0000 7798.0000 8347.0000 7641.0000 4799.0000 5956.0000 Uracil 617285.0000 561450.0000 560207.0000 536688.0000 588070.0000 707631.0000 748619.0000 630507.0000 703880.0000 732551.0000 689298.0000 686198.0000 577273.0000 715978.0000 637131.0000 593035.0000 354.0000 25743.0000 470508.0000 473403.0000 413797.0000 530568.0000 538344.0000 449807.0000 523596.0000 411805.0000 646772.0000 747218.0000 693335.0000 882355.0000 Urea 66762.0000 56828.0000 57248.0000 47942.0000 44542.0000 47383.0000 72701.0000 47305.0000 23769.0000 31091.0000 20976.0000 21299.0000 45450.0000 27653.0000 23212.0000 25382.0000 2528.0000 3529.0000 16894.0000 11359.0000 12061.0000 7107.0000 43200.0000 35075.0000 45670.0000 35236.0000 5073.0000 5806.0000 2543.0000 4991.0000 Xanthurenic acid 820.0000 1085.0000 470.0000 602.0000 1308.0000 504.0000 118.0000 718.0000 539.0000 294.0000 227.0000 121.0000 275.0000 340.0000 2588.0000 606.0000 1003.0000 1081.0000 431.0000 1356.0000 MS_METABOLITE_DATA_END #METABOLITES METABOLITES_START metabolite_name pubchem_id inchi_key kegg_id other_id other_id_type ri ri_type moverz_quant 1,6-anhydro-Glucose 1-Monomyristin 1-Octadecene 1-Palmitoylglycerol 1-Steroylglycerol 2-Hydroxybutyric acid 2-Hydroxyglutaric acid 2-Ketoglutamic acid 2-Ketoisocaproic acid 2-Monopalmitoylglycerol 2-Steroylglycerol 3-Hydroxybutyrate 3-Phosphoglyceric acid 4-Hydroxyproline 1 4-Hydroxyproline 2 Adenine Adenosine Adenosine monophosphate Adipic acid Allantoin alpha-D-Glucosamine 1-phosphate Arachidic acid Arachidonic Acid Azelaic acid Benzoic acid Beta-Alanine Beta-Glycerophosphoric acid Capric acid Cellobiose Cholesterol cis-Aconitic acid Citric acid Creatinine Cystathionine d4-succinate D-Fructose 1 D-Fructose 2 D-Galactose D-Glucose 1 D-Glucose 2 D-Malic acid D-Mannose D-Ribose-5-phosphate D-Threitol Eicosane Elaidic acid Ergosterol Ethanolamine 1 Ethanolamine 2 Fructose 1,6-diphosphate Fructose 6-phosphate Fumaric acid Galactonic acid Glucose 6-phosphate Glutamic acid Glutamine Glutathione Glyceraldehyde 3-phosphate Glycerol Glycerol 3-phosphate Glycine Glycolic acid Glyoxylic acid Guanine Heptadecanoic acid Heptanoic acid Homoserine 1 Homoserine 2 Hypoxanthine Iminodiacetic acid Inosine Inosine 5-monophosphate Inositol phosphate Isocitric acid Itaconic acid L-Alanine Lanosterol L-Ascorbic acid L-Asparagine L-Aspartic acid 1 L-Aspartic acid 2 Lauric Acid L-Glutamic acid L-Gulonic acid gamma-lactone Linoleic acid L-Isoleucine 1 L-Isoleucine 2 L-Lactic acid L-Leucine 1 L-Leucine 2 L-Lysine L-Methionine 1 L-Methionine 2 L-Phenylalanine 1 L-Phenylalanine 2 L-Proline 1 L-Proline 2 L-Serine 1 L-Serine 2 L-Sorbose L-Threonine 1 L-Threonine 2 L-Tyrosine 1 L-Tyrosine 2 L-Valine 1 L-Valine 2 Malonic acid methyl-beta-D-Galactopyranoside Methylmalonic acid Myoinositol Myristic acid Myristic Acid d27 N-acetyl-L-aspartic acid N-acetyl-Lysine Nicotinamide Nitrous Oxide Nonanoic acid Oleic acid O-Phosphoethanolamine Ornithine Orotic acid Oxalic acid Palmitic acid Palmitoleic acid Phosphate Phosphatidyl Glycerol Phosphoenolpyruvate Putrescine Pyroglutamic acid Pyrophosphate Pyrrolidonecarboxylic acid Pyruvic acid Ribitol Ribonic acid-gamma-lactone Sedoheptulose 7-phosphate Sophorose Sorbitol Stearic acid Succinic acid Sucrose Taurine Threonic acid Thymine Trehalose Turanose Uracil Urea Xanthurenic acid METABOLITES_END #END